Year |
Citation |
Score |
2021 |
Siddiq MM, Hannila SS, Zorina Y, Nikulina E, Rabinovich V, Hou J, Huq R, Richman EL, Tolentino RE, Hansen J, Velenosi A, Kwon BK, Tsirka SE, Maze I, Sebra R, et al. Extracellular histones, a new class of inhibitory molecules of CNS axonal regeneration. Brain Communications. 3: fcab271. PMID 34993473 DOI: 10.1093/braincomms/fcab271 |
0.593 |
|
2020 |
Victor TR, Tsirka SE. Microglial contributions to aberrant neurogenesis and pathophysiology of epilepsy. Neuroimmunology and Neuroinflammation. 7: 234-247. PMID 33154976 DOI: 10.20517/2347-8659.2020.02 |
0.327 |
|
2020 |
Torres L, Tsirka S. . The Journal of Pharmacology and Experimental Therapeutics. PMID 32817207 DOI: 10.1124/Jpet.120.000261 |
0.529 |
|
2019 |
Kyle J, Wu M, Gourzi S, Tsirka SE. Proliferation and Differentiation in the Adult Subventricular Zone Are Not Affected by CSF1R Inhibition. Frontiers in Cellular Neuroscience. 13: 97. PMID 31001085 DOI: 10.3389/Fncel.2019.00097 |
0.529 |
|
2019 |
Thompson KK, Tsirka SE. Guanabenz Modulates Microglia and Macrophages in EAE The Faseb Journal. 33. DOI: 10.1096/Fasebj.2019.33.1_Supplement.501.6 |
0.331 |
|
2018 |
Thompson KK, Nissen JC, Pretory A, Tsirka SE. Tuftsin Combines With Remyelinating Therapy and Improves Outcomes in Models of CNS Demyelinating Disease. Frontiers in Immunology. 9: 2784. PMID 30555470 DOI: 10.3389/Fimmu.2018.02784 |
0.313 |
|
2018 |
Caponegro MD, Torres LF, Rastegar C, Rath N, Anderson ME, Robinson JK, Tsirka SE. Pifithrin-μ modulates microglial activation and promotes histological recovery following spinal cord injury. Cns Neuroscience & Therapeutics. PMID 29962076 DOI: 10.1111/Cns.13000 |
0.627 |
|
2018 |
Nissen JC, Thompson KK, West BL, Tsirka SE. Csf1R inhibition attenuates experimental autoimmune encephalomyelitis and promotes recovery. Experimental Neurology. PMID 29803827 DOI: 10.1016/J.Expneurol.2018.05.021 |
0.374 |
|
2018 |
Preston AN, Farr JD, O'Neill BK, Thompson KK, Tsirka SE, Laughlin ST. Visualizing the brain's astrocytes with diverse chemical scaffolds. Acs Chemical Biology. PMID 29733639 DOI: 10.1021/Acschembio.8B00391 |
0.36 |
|
2017 |
Miyauchi JT, Caponegro MD, Chen D, Choi MK, Li M, Tsirka SE. Deletion of neuropilin 1 from microglia or bone marrow-derived macrophages slows glioma progression. Cancer Research. PMID 29097606 DOI: 10.1158/0008-5472.Can-17-1435 |
0.321 |
|
2017 |
Bronstein R, Kyle J, Abraham AB, Tsirka SE. Neurogenic to Gliogenic Fate Transition Perturbed by Loss of HMGB2. Frontiers in Molecular Neuroscience. 10: 153. PMID 28588451 DOI: 10.3389/Fnmol.2017.00153 |
0.776 |
|
2017 |
Thompson KK, Tsirka SE. The Diverse Roles of Microglia in the Neurodegenerative Aspects of Central Nervous System (CNS) Autoimmunity. International Journal of Molecular Sciences. 18. PMID 28245617 DOI: 10.3390/Ijms18030504 |
0.377 |
|
2017 |
Bronstein R, Tsirka SE. Tissue Plasminogen Activator Signaling in the Normal and Diseased Brain Primer On Cerebrovascular Diseases. 288-291. DOI: 10.1016/B978-0-12-803058-5.00060-6 |
0.684 |
|
2016 |
Lewis CS, Torres L, Miyauchi JT, Rastegar C, Patete JM, Smith JM, Wong SS, Tsirka SE. Absence of Cytotoxicity towards Microglia of Iron Oxide (α-Fe2O3) Nanorhombohedra. Toxicology Research. 5: 836-847. PMID 27274811 DOI: 10.1039/C5Tx00421G |
0.579 |
|
2016 |
Nissen JC, Tsirka SE. Tuftsin-driven experimental autoimmune encephalomyelitis recovery requires neuropilin-1. Glia. PMID 26880314 DOI: 10.1002/Glia.22972 |
0.36 |
|
2016 |
Miyauchi JT, Chen D, Choi M, Nissen JC, Shroyer KR, Djordevic S, Zachary IC, Selwood D, Tsirka SE. Ablation of neuropilin 1 from glioma-associated microglia and macrophages slows tumor progression. Oncotarget. PMID 26755653 DOI: 10.18632/Oncotarget.6877 |
0.364 |
|
2016 |
Miyauchi JT, Chen D, Choi M, Nissen J, Shroyer K, Selwood D, Tsirka SE. Abstract A129: Ablation of neuropilin 1 from glioma associated macrophages and microglia slows tumor progression Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A129 |
0.353 |
|
2015 |
Bukhari N, Burman PN, Hussein A, Demars MP, Sadahiro M, Brady DM, Tsirka SE, Russo SJ, Morishita H. Unmasking Proteolytic Activity for Adult Visual Cortex Plasticity by the Removal of Lynx1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 12693-702. PMID 26377459 DOI: 10.1523/Jneurosci.4315-14.2015 |
0.634 |
|
2015 |
Torres L, Danver J, Ji K, Miyauchi JT, Chen D, Anderson ME, L West B, Robinson JK, Tsirka SE. Dynamic microglial modulation of spatial learning and social behavior. Brain, Behavior, and Immunity. PMID 26348580 DOI: 10.1016/J.Bbi.2015.09.001 |
0.59 |
|
2015 |
Gao Z, Nissen JC, Legakis L, Tsirka SE. Nicotine modulates neurogenesis in the central canal during experimental autoimmune encephalomyelitis. Neuroscience. 297: 11-21. PMID 25813705 DOI: 10.1016/J.Neuroscience.2015.03.031 |
0.493 |
|
2014 |
Gao Z, Nissen JC, Ji K, Tsirka SE. The experimental autoimmune encephalomyelitis disease course is modulated by nicotine and other cigarette smoke components Plos One. 9. PMID 25250777 DOI: 10.1371/Journal.Pone.0107979 |
0.423 |
|
2014 |
Yao Y, Tsirka SE. Mouse monocyte chemoattractant protein 1 (MCP1) functions as a monomer. The International Journal of Biochemistry & Cell Biology. 55: 51-9. PMID 25130440 DOI: 10.1016/J.Biocel.2014.08.002 |
0.345 |
|
2014 |
He Y, Yao Y, Tsirka SE, Cao Y. Cell-culture models of the blood-brain barrier Stroke. 45: 2514-2526. PMID 24938839 DOI: 10.1161/Strokeaha.114.005427 |
0.334 |
|
2014 |
Yao Y, Tsirka SE. Monocyte chemoattractant protein-1 and the blood-brain barrier Cellular and Molecular Life Sciences. 71: 683-697. PMID 24051980 DOI: 10.1007/S00018-013-1459-1 |
0.343 |
|
2013 |
Abraham AB, Bronstein R, Reddy AS, Maletic-Savatic M, Aguirre A, Tsirka SE. Aberrant neural stem cell proliferation and increased adult neurogenesis in mice lacking chromatin protein HMGB2. Plos One. 8: e84838. PMID 24391977 DOI: 10.1371/Journal.Pone.0084838 |
0.79 |
|
2013 |
Ji K, Miyauchi J, Tsirka SE. Microglia: An active player in the regulation of synaptic activity Neural Plasticity. 2013. PMID 24303218 DOI: 10.1155/2013/627325 |
0.34 |
|
2013 |
Bronstein R, Torres L, Nissen JC, Tsirka SE. Culturing microglia from the neonatal and adult central nervous system. Journal of Visualized Experiments : Jove. PMID 23962915 DOI: 10.3791/50647 |
0.77 |
|
2013 |
Abraham AB, Bronstein R, Chen EI, Koller A, Ronfani L, Maletic-Savatic M, Tsirka SE. Members of the high mobility group B protein family are dynamically expressed in embryonic neural stem cells. Proteome Science. 11: 18. PMID 23621913 DOI: 10.1186/1477-5956-11-18 |
0.773 |
|
2013 |
Ji K, Akgul G, Wollmuth LP, Tsirka SE. Microglia actively regulate the number of functional synapses. Plos One. 8: e56293. PMID 23393609 DOI: 10.1371/Journal.Pone.0056293 |
0.352 |
|
2013 |
Louie E, Chen XF, Coomes A, Ji K, Tsirka S, Chen EI. Neurotrophin-3 modulates breast cancer cells and the microenvironment to promote the growth of breast cancer brain metastasis Oncogene. 32: 4064-4077. PMID 23001042 DOI: 10.1038/Onc.2012.417 |
0.739 |
|
2012 |
Yao Y, Tsirka SE. Chemokines and their receptors in intracerebral hemorrhage. Translational Stroke Research. 3: 70-9. PMID 24323863 DOI: 10.1007/S12975-012-0155-Z |
0.37 |
|
2012 |
Hedhli N, Falcone DJ, Huang B, Cesarman-Maus G, Kraemer R, Zhai H, Tsirka SE, Santambrogio L, Hajjar KA. The annexin A2/S100A10 system in health and disease: Emerging paradigms Journal of Biomedicine and Biotechnology. 2012. PMID 23193360 DOI: 10.1155/2012/406273 |
0.529 |
|
2012 |
Ji K, Tsirka SE. Inflammation modulates expression of laminin in the central nervous system following ischemic injury Journal of Neuroinflammation. 9. PMID 22759265 DOI: 10.1186/1742-2094-9-159 |
0.392 |
|
2012 |
Emmetsberger J, Tsirka SE. Microglial inhibitory factor (MIF/TKP) mitigates secondary damage following spinal cord injury Neurobiology of Disease. 47: 295-309. PMID 22613732 DOI: 10.1016/J.Nbd.2012.05.001 |
0.795 |
|
2012 |
Wu M, Nissen JC, Chen EI, Tsirka SE. Tuftsin promotes an anti-inflammatory switch and attenuates symptoms in experimental autoimmune encephalomyelitis Plos One. 7. PMID 22529957 DOI: 10.1371/Journal.Pone.0034933 |
0.485 |
|
2012 |
Yao Y, Tsirka SE. The CCL2-CCR2 system affects the progression and clearance of intracerebral hemorrhage Glia. 60: 908-918. PMID 22419223 DOI: 10.1002/Glia.22323 |
0.414 |
|
2011 |
Gao Z, Tsirka SE. Animal Models of MS Reveal Multiple Roles of Microglia in Disease Pathogenesis. Neurology Research International. 2011: 383087. PMID 22203900 DOI: 10.1155/2011/383087 |
0.49 |
|
2011 |
Bukhari N, Torres L, Robinson JK, Tsirka SE. Axonal regrowth after spinal cord injury via chondroitinase and the tissue plasminogen activator (tPA)/plasmin system Journal of Neuroscience. 31: 14931-14943. PMID 22016526 DOI: 10.1523/Jneurosci.3339-11.2011 |
0.745 |
|
2011 |
Zhai H, Acharya S, Gravanis I, Mehmood S, Seidman RJ, Shroyer KR, Hajjar KA, Tsirka SE. Annexin A2 promotes glioma cell invasion and tumor progression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14346-60. PMID 21976520 DOI: 10.1523/Jneurosci.3299-11.2011 |
0.536 |
|
2011 |
Yao Y, Tsirka SE. Mouse MCP1 C-terminus inhibits human MCP1-induced chemotaxis and BBB compromise Journal of Neurochemistry. 118: 215-223. PMID 21615737 DOI: 10.1111/J.1471-4159.2011.07319.X |
0.322 |
|
2011 |
Yao Y, Tsirka SE. Truncation of monocyte chemoattractant protein 1 by plasmin promotes blood-brain barrier disruption Journal of Cell Science. 124: 1486-1495. PMID 21486949 DOI: 10.1242/Jcs.082834 |
0.396 |
|
2011 |
Zhai H, Heppner FL, Tsirka SE. Microglia/macrophages promote glioma progression Glia. 59: 472-485. PMID 21264953 DOI: 10.1002/Glia.21117 |
0.546 |
|
2011 |
Louie E, Coomes A, Chen XF, Schmidt M, Ji K, Tsirka S, Chen EI. Abstract A1: NT-3 modulates HER2 signaling to promote the metastatic growth of HER2-positive breast cancer brain metastasis Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-A1 |
0.731 |
|
2011 |
Gao Z, Tsirka SE. Animal models of MS reveal multiple roles of microglia in disease pathogenesis Neurology Research International. 2011. DOI: 10.1155/2011/383087 |
0.369 |
|
2010 |
Talos F, Abraham A, Vaseva AV, Holembowski L, Tsirka SE, Scheel A, Bode D, Dobbelstein M, Brück W, Moll UM. P73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis Cell Death and Differentiation. 17: 1816-1829. PMID 21076477 DOI: 10.1038/Cdd.2010.131 |
0.784 |
|
2010 |
Sierra A, Encinas JM, Deudero JJ, Chancey JH, Enikolopov G, Overstreet-Wadiche LS, Tsirka SE, Maletic-Savatic M. Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis. Cell Stem Cell. 7: 483-95. PMID 20887954 DOI: 10.1016/J.Stem.2010.08.014 |
0.358 |
|
2010 |
Yao Y, Tsirka SE. The C terminus of Mouse Monocyte Chemoattractant Protein 1 (MCP1) mediates MCP1 dimerization while blocking its chemotactic potency Journal of Biological Chemistry. 285: 31509-31516. PMID 20682771 DOI: 10.1074/Jbc.M110.124891 |
0.359 |
|
2010 |
Emmetsberger J, Mirrione MM, Zhou C, Fernandez-Monreal M, Siddiq MM, Ji K, Tsirka SE. Tissue plasminogen activator alters intracellular sequestration of zinc through interaction with the transporter ZIP4 Journal of Neuroscience. 30: 6538-6547. PMID 20463217 DOI: 10.1523/Jneurosci.6250-09.2010 |
0.787 |
|
2010 |
Pothakos K, Robinson JK, Gravanis I, Marsteller DA, Dewey SL, Tsirka SE. Decreased serotonin levels associated with behavioral disinhibition in tissue plasminogen activator deficient (tPA-/-) mice Brain Research. 1326: 135-142. PMID 20156421 DOI: 10.1016/J.Brainres.2009.12.095 |
0.313 |
|
2009 |
Wu M, Tsirka SE. Endothelial NOS-deficient mice reveal dual roles for nitric oxide during experimental autoimmune encephalomyelitis Glia. 57: 1204-1215. PMID 19170181 DOI: 10.1002/Glia.20842 |
0.497 |
|
2008 |
Gao Z, Wang J, Thiex R, Rogove AD, Heppner FL, Tsirka SE. Microglial activation and intracerebral hemorrhage Acta Neurochirurgica, Supplementum. 51-53. PMID 19066082 DOI: 10.1007/978-3-211-09469-3_11 |
0.429 |
|
2008 |
Nolin WB, Emmetsberger J, Bukhari N, Zhang Y, Levine JM, Tsirka SE. tPA-mediated generation of plasmin is catalyzed by the proteoglycan NG2 Glia. 56: 177-189. PMID 18000864 DOI: 10.1002/Glia.20603 |
0.711 |
|
2007 |
Mirrione MM, Schiffer WK, Fowler JS, Alexoff DL, Dewey SL, Tsirka SE. A novel approach for imaging brain-behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator. Neuroimage. 38: 34-42. PMID 17707126 DOI: 10.1016/J.Neuroimage.2007.06.032 |
0.315 |
|
2007 |
Bhasin M, Wu M, Tsirka SE. Modulation of microglial/macrophage activation by macrophage inhibitory factor (TKP) or tuftsin (TKPR) attenuates the disease course of experimental autoimmune encephalomyelitis Bmc Immunology. 8. PMID 17634104 DOI: 10.1186/1471-2172-8-10 |
0.675 |
|
2007 |
Thiex R, Tsirka SE. Brain edema after intracerebral hemorrhage: mechanisms, treatment options, management strategies, and operative indications. Neurosurgical Focus. 22: E6. PMID 17613237 DOI: 10.3171/Foc.2007.22.5.7 |
0.32 |
|
2007 |
Parathath SR, Gravanis I, Tsirka SE. Nitric oxide synthase isoforms undertake unique roles during excitotoxicity Stroke. 38: 1938-1945. PMID 17446423 DOI: 10.1161/Strokeaha.106.478826 |
0.788 |
|
2007 |
Sheehan JJ, Zhou C, Gravanis I, Rogove AD, Wu YP, Bogenhagen DF, Tsirka SE. Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1738-45. PMID 17301181 DOI: 10.1523/Jneurosci.4987-06.2007 |
0.639 |
|
2006 |
Parathath SR, Parathath S, Tsirka SE. Nitric oxide mediates neurodegeneration and breakdown of the blood-brain barrier in tPA-dependent excitotoxic injury in mice Journal of Cell Science. 119: 339-349. PMID 16410551 DOI: 10.1242/Jcs.02734 |
0.803 |
|
2006 |
Mirrione MM, Schiffer WK, Siddiq M, Dewey SL, Tsirka SE. PET imaging of glucose metabolism in a mouse model of temporal lobe epilepsy Synapse. 59: 119-121. PMID 16320304 DOI: 10.1002/Syn.20216 |
0.571 |
|
2006 |
Tsirka S, Gravanis I, Sheehan J, Zhou C, Parathath S. ID: 218 Tissue plasminogen activator and the interplay between neurons and microglia Journal of Thrombosis and Haemostasis. 4: 60-60. DOI: 10.1111/j.1538-7836.2006.00218.x |
0.58 |
|
2005 |
Wang J, Tsirka SE. Contribution of extracellular proteolysis and microglia to intracerebral hemorrhage Neurocritical Care. 3: 77-85. PMID 16159103 DOI: 10.1385/Ncc:3:1:077 |
0.427 |
|
2005 |
Xanthopoulos K, Paspaltsis I, Apostolidou V, Petrakis S, Siao CJ, Kalpatsanidis A, Grigoriadis N, Tsaftaris A, Tsirka SE, Sklaviadis T. Tissue plasminogen activator in brain tissues infected with transmissible spongiform encephalopathies Neurobiology of Disease. 20: 519-527. PMID 15922607 DOI: 10.1016/J.Nbd.2005.04.008 |
0.732 |
|
2005 |
Sheehan JJ, Tsirka SE. Fibrin-modifying serine proteases thrombin, tPA, and plasmin in ischemic stroke: A review Glia. 50: 340-350. PMID 15846799 DOI: 10.1002/Glia.20150 |
0.573 |
|
2005 |
Wang J, Tsirka SE. Neuroprotection by inhibition of matrix metalloproteinases in a mouse model of intracerebral haemorrhage Brain. 128: 1622-1633. PMID 15800021 DOI: 10.1093/Brain/Awh489 |
0.391 |
|
2005 |
Zhang Y, Kanaho Y, Frohman MA, Tsirka SE. Phospholipase D1-promoted release of tissue plasminogen activator facilitates neurite outgrowth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 1797-805. PMID 15716416 DOI: 10.1523/Jneurosci.4850-04.2005 |
0.364 |
|
2005 |
Wang J, Tsirka SE. Tuftsin fragment 1-3 is beneficial when delivered after the induction of intracerebral hemorrhage Stroke. 36: 613-618. PMID 15692122 DOI: 10.1161/01.Str.0000155729.12931.8F |
0.424 |
|
2005 |
Gravanis I, Tsirka SE. Tissue plasminogen activator and glial function Glia. 49: 177-183. PMID 15494978 DOI: 10.1002/Glia.20115 |
0.412 |
|
2005 |
Wang J, Gravanis I, Sheehan J, Tsirka S. tPA as an effector of microglial activation Journal of Cerebral Blood Flow & Metabolism. 25: S686-S686. DOI: 10.1038/Sj.Jcbfm.9591524.0686 |
0.638 |
|
2004 |
Zhang Y, Huang P, Du G, Kanaho Y, Frohman MA, Tsirka SE. Increased expression of two phospholipase D isoforms during experimentally induced hippocampal mossy fiber outgrowth. Glia. 46: 74-83. PMID 14999815 DOI: 10.1002/Glia.10322 |
0.406 |
|
2004 |
Siddiq MM, Tsirka SE. Modulation of zinc toxicity by tissue plasminogen activator Molecular and Cellular Neuroscience. 25: 162-171. PMID 14962749 DOI: 10.1016/J.Mcn.2003.10.007 |
0.654 |
|
2003 |
Wang J, Rogove AD, Tsirka AE, Tsirka SE. Protective Role of Tuftsin Fragment 1-3 in an Animal Model of Intracerebral Hemorrhage Annals of Neurology. 54: 655-664. PMID 14595655 DOI: 10.1002/Ana.10750 |
0.458 |
|
2003 |
Siao CJ, Fernandez SR, Tsirka SE. Cell type-specific roles for tissue plasminogen activator released by neurons or microglia after excitotoxic injury Journal of Neuroscience. 23: 3234-3242. PMID 12716930 DOI: 10.1523/Jneurosci.23-08-03234.2003 |
0.779 |
|
2003 |
Indyk JA, Chen ZL, Tsirka SE, Strickland S. Laminin chain expression suggests that laminin-10 is a major isoform in the mouse hippocampus and is degraded by the tissue plasminogen activator/plasmin protease cascade during excitotoxic injury Neuroscience. 116: 359-371. PMID 12559092 DOI: 10.1016/S0306-4522(02)00704-2 |
0.785 |
|
2002 |
Lu W, Bhasin M, Tsirka SE. Involvement of tissue plasminogen activator in onset and effector phases of experimental allergic encephalomyelitis Journal of Neuroscience. 22: 10781-10789. PMID 12486171 DOI: 10.1523/Jneurosci.22-24-10781.2002 |
0.716 |
|
2002 |
Rogove AD, Lu W, Tsirka SE. Microglial activation and recruitment, but not proliferation, suffice to mediate neurodegeneration Cell Death and Differentiation. 9: 801-806. PMID 12107823 DOI: 10.1038/Sj.Cdd.4401041 |
0.629 |
|
2002 |
Tsirka SE. Tissue plasminogen activator as a modulator of neuronal survival and function. Biochemical Society Transactions. 30: 222-225. PMID 12023855 DOI: 10.1042/Bst0300222 |
0.481 |
|
2002 |
Siao CJ, Tsirka SE. Extracellular proteases and neuronal cell death. Cellular and Molecular Biology. 48: 151-161. PMID 11990450 |
0.729 |
|
2002 |
Siao CJ, Tsirka SE. Tissue Plasminogen Activator Mediates Microglial Activation via Its Finger Domain through Annexin II Journal of Neuroscience. 22: 3352-3358. PMID 11978811 DOI: 10.1523/Jneurosci.22-09-03352.2002 |
0.766 |
|
2002 |
Lu W, Tsirka SE. Partial rescue of neural apoptosis in the Lurcher mutant mouse through elimination of tissue plasminogen activator Development. 129: 2043-2050. PMID 11934869 |
0.588 |
|
2002 |
Tsirka SE. tPA as a modulator of neuronal survival and function Biochemical Society Transactions. 30. DOI: 10.1042/Bst030A015B |
0.328 |
|
2001 |
Mori T, Wang X, Kline AE, Siao CJ, Dixon CE, Tsirka SE, Lo EH. Reduced cortical injury and edema in tissue plasminogen activator knockout mice after brain trauma. Neuroreport. 12: 4117-20. PMID 11742249 DOI: 10.1097/00001756-200112210-00051 |
0.72 |
|
2000 |
Wu YP, Siao CJ, Lu W, Sung TC, Frohman MA, Milev P, Bugge TH, Degen JL, Levine JM, Margolis RU, Tsirka SE. The tissue plasminogen activator (tPA)/plasmin extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber outgrowth through a proteoglycan substrate. The Journal of Cell Biology. 148: 1295-304. PMID 10725341 DOI: 10.1083/Jcb.148.6.1295 |
0.752 |
|
1999 |
Rogove AD, Siao CJ, Keyt B, Strickland S, Tsirka SE. Activation of microglia reveals a non-proteolytic cytokine function for tissue plasminogen activator in the central nervous system Journal of Cell Science. 112: 4007-4016. PMID 10547361 |
0.788 |
|
1998 |
Wang YF, Tsirka SE, Strickland S, Stieg PE, Soriano SG, Lipton SA. Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice. Nature Medicine. 4: 228-31. PMID 9461198 DOI: 10.1038/Nm0298-228 |
0.587 |
|
1998 |
Rogove AD, Tsirka SE. Neurotoxic responses by microglia elicited by excitotoxic injury in the mouse hippocampus Current Biology. 8: 19-25. PMID 9427623 DOI: 10.1016/S0960-9822(98)70016-8 |
0.485 |
|
1997 |
Mecenas PE, Tsirka SE, Sallés F, Strickland S. Removal of tissue plasminogen activator does not protect against neuronal degeneration in the cerebellum of the weaver mouse Brain Research. 772: 233-238. PMID 9406977 DOI: 10.1016/S0006-8993(97)00864-0 |
0.634 |
|
1997 |
Tsirka SE, Bugge TH, Degen JL, Strickland S. Neuronal death in the central nervous system demonstrates a non-fibrin substrate for plasmin Proceedings of the National Academy of Sciences of the United States of America. 94: 9779-9781. PMID 9275201 DOI: 10.1073/Pnas.94.18.9779 |
0.598 |
|
1997 |
Tsirka SE. Clinical implications of the involvement of tPA in neuronal cell death Journal of Molecular Medicine. 75: 341-347. PMID 9181475 DOI: 10.1007/S001090050119 |
0.487 |
|
1997 |
Tsirka SE, Rogove AD, Bugge TH, Degen JL, Strickland S. An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus Journal of Neuroscience. 17: 543-552. PMID 8987777 DOI: 10.1523/Jneurosci.17-02-00543.1997 |
0.645 |
|
1997 |
Tsirka SE, Chen Z, Strickland S. 54 A tPA/plasmin proteolytic cascade promotes neuronal degeneration in the mammalian hippocampus Fibrinolysis and Proteolysis. 11: 15. DOI: 10.1016/S0268-9499(97)80169-5 |
0.597 |
|
1996 |
Strickland S, Gualandris A, Rogove AD, Tsirka SE. Extracellular proteases in neuronal function and degeneration Cold Spring Harbor Symposia On Quantitative Biology. 61: 739-745. PMID 9246499 DOI: 10.1101/Sqb.1996.061.01.073 |
0.577 |
|
1996 |
Tsirka SE, Rogove AD, Strickland S. Neuronal cell death and tPA [4] Nature. 384: 123-124. PMID 8906786 DOI: 10.1038/384123B0 |
0.581 |
|
1996 |
West MF, Verrotti AC, Sallés FJ, Tsirka SE, Strickland S. Isolation and characterization of two novel, cytoplasmically polyadenylated, oocyte-specific, mouse maternal RNAs Developmental Biology. 175: 132-141. PMID 8608859 DOI: 10.1006/Dbio.1996.0101 |
0.514 |
|
1996 |
Gualandris A, Jones TE, Strickland S, Tsirka SE. Membrane depolarization induces calcium-dependent secretion of tissue plasminogen activator Journal of Neuroscience. 16: 2220-2225. PMID 8601802 DOI: 10.1523/Jneurosci.16-07-02220.1996 |
0.615 |
|
1995 |
Tsirka SE, Gualandris A, Amaral DG, Strickland S. Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator. Nature. 377: 340-4. PMID 7566088 DOI: 10.1038/377340A0 |
0.637 |
|
1994 |
Carroll PM, Tsirka SE, Richards WG, Frohman MA, Strickland S. The mouse tissue plasminogen activator gene 5′ flanking region directs appropriate expression in development and a seizure-enhanced response in the CNS Development. 120: 3173-3183. PMID 7720560 |
0.54 |
|
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