| Year |
Citation |
Score |
| 2023 |
Lefkowitz RJ, Rockman HA, Shim PJ, Liu S, Ahn S, Pani B, Rajagopal S, Shenoy SK, Bouvier M, Benovic JL, Liggett SB, Ruffolo RR, Bristow MR, Packer M. How carvedilol does not activate β-adrenoceptors. Nature Communications. 14: 7866. PMID 38036531 DOI: 10.1038/s41467-023-42848-5 |
0.761 |
|
| 2023 |
Eiger DS, Hicks C, Gardner J, Pham U, Rajagopal S. Location bias: A "Hidden Variable" in GPCR pharmacology. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2300123. PMID 37625014 DOI: 10.1002/bies.202300123 |
0.834 |
|
| 2023 |
Ghadimi K, Cappiello JL, Wright MC, Levy JH, Bryner BS, DeVore AD, Schroder JN, Patel CB, Rajagopal S, Shah SH, Milano CA. Inhaled Epoprostenol Compared With Nitric Oxide for Right Ventricular Support After Major Cardiac Surgery. Circulation. PMID 37401479 DOI: 10.1161/CIRCULATIONAHA.122.062464 |
0.362 |
|
| 2023 |
Eiger DS, Smith JS, Shi T, Stepniewski TM, Tsai CF, Honeycutt C, Boldizsar N, Gardner J, Nicora CD, Moghieb AM, Kawakami K, Choi I, Hicks C, Zheng K, Warman A, ... ... Rajagopal S, et al. Phosphorylation barcodes direct biased chemokine signaling at CXCR3. Cell Chemical Biology. PMID 37030291 DOI: 10.1016/j.chembiol.2023.03.006 |
0.831 |
|
| 2023 |
Eiger DS, Smith JS, Shi T, Stepniewski TM, Tsai CF, Honeycutt C, Boldizsar N, Gardner J, Nicora CD, Moghieb AM, Kawakami K, Choi I, Zheng K, Warman A, Alagesan P, ... ... Rajagopal S, et al. Phosphorylation barcodes direct biased chemokine signaling at CXCR3. Biorxiv : the Preprint Server For Biology. PMID 36993369 DOI: 10.1101/2023.03.14.532634 |
0.834 |
|
| 2022 |
Eiger DS, Boldizsar N, Honeycutt CC, Gardner J, Kirchner S, Hicks C, Choi I, Pham U, Zheng K, Warman A, Smith JS, Zhang JY, Rajagopal S. Location bias contributes to functionally selective responses of biased CXCR3 agonists. Nature Communications. 13: 5846. PMID 36195635 DOI: 10.1038/s41467-022-33569-2 |
0.834 |
|
| 2022 |
Pham U, Chundi A, Rajagopal S. Distinct Spatial Conformations and Trafficking Patterns of β-arrestin Isoforms in AT1R Signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35559563 DOI: 10.1096/fasebj.2022.36.S1.L7742 |
0.324 |
|
| 2022 |
Gardner J, Eiger D, Boldizsar N, Honeycutt CC, Kirchner S, Hicks C, Choi I, Zheng K, Warman A, Smith J, Zhang J, Rajagopal S. Location Bias Contributes to Functionally Selective Responses of Biased CXCR3 Agonists to Regulate Inflammation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35555971 DOI: 10.1096/fasebj.2022.36.S1.0R865 |
0.415 |
|
| 2022 |
Kohlmann T, Lee C, Rajagopal S. Determining the Requirements for Gαi:β-arrestin Complex Formation at G Protein-Coupled Receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35554641 DOI: 10.1096/fasebj.2022.36.S1.R5812 |
0.374 |
|
| 2022 |
Eiger DS, Smith J, Shi T, Stepniewski TM, Honeycutt C, Boldizsar N, Gardner J, Tsai CF, Nicora C, Moghieb A, Kawakami K, Choi I, Smith R, Inoue A, Selent J, ... ... Rajagopal S, et al. Phosphorylation barcode ensembles encoded by biased CXCR3 agonists direct non-redundant chemokine signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35554623 DOI: 10.1096/fasebj.2022.36.S1.0R486 |
0.42 |
|
| 2022 |
Lee C, Kohlmann T, Xiong X, Rajagopal S. Regulation of Endothelial Cell function by Integration of Gαi and β-arrestin signaling at Atypical Chemokine Receptor 3. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35554058 DOI: 10.1096/fasebj.2022.36.S1.R6324 |
0.381 |
|
| 2022 |
Hicks CN, Eiger D, Gardner J, Boldizsar N, Honeycutt C, Choi I, Rajagopal S. Location Bias of G Protein-Coupled Receptor Kinases Promotes Biased Signaling at CXCR3. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35554028 DOI: 10.1096/fasebj.2022.36.S1.R2182 |
0.428 |
|
| 2022 |
Zheng K, Smith JS, Eiger DS, Warman A, Choi I, Honeycutt CC, Boldizsar N, Gundry JN, Pack TF, Inoue A, Caron MG, Rajagopal S. Biased agonists of the chemokine receptor CXCR3 differentially signal through Gα:β-arrestin complexes. Science Signaling. 15: eabg5203. PMID 35316095 DOI: 10.1126/scisignal.abg5203 |
0.82 |
|
| 2022 |
Eiger DS, Pham U, Gardner J, Hicks C, Rajagopal S. GPCR Systems Pharmacology: A Different Perspective on the Development of Biased Therapeutics. American Journal of Physiology. Cell Physiology. PMID 35196164 DOI: 10.1152/ajpcell.00449.2021 |
0.814 |
|
| 2022 |
Kolb P, Kenakin T, Alexander SPH, Bermudez M, Bohn LM, Breinholt CS, Bouvier M, Hill SJ, Kostenis E, Martemyanov K, Neubig RR, Onaran HO, Rajagopal S, Roth BL, Selent J, et al. Community Guidelines for GPCR Ligand Bias: IUPHAR Review XX. British Journal of Pharmacology. PMID 35106752 DOI: 10.1111/bph.15811 |
0.632 |
|
| 2021 |
Xiong X, Nazo N, Revoori R, Rajagopal S, Sparks MA. G protein- and -arrestin Signaling Profiles of Endothelin Derivatives at the Type A Endothelin Receptor. Kidney360. 2: 1124-1131. PMID 35368349 DOI: 10.34067/KID.0005462020 |
0.343 |
|
| 2021 |
Suwanpradid J, Lee MJ, Hoang P, Kwock J, Floyd LP, Smith JS, Yin Z, Atwater AR, Rajagopal S, Kedl RM, Corcoran DL, Zhang JY, MacLeod AS. IL-27 Derived From Macrophages Facilitates IL-15 Production and T Cell Maintenance Following Allergic Hypersensitivity Responses. Frontiers in Immunology. 12: 713304. PMID 34659203 DOI: 10.3389/fimmu.2021.713304 |
0.467 |
|
| 2021 |
Nathan SD, Waxman A, Rajagopal S, Case A, Johri S, DuBrock H, De La Zerda DJ, Sahay S, King C, Melendres-Groves L, Smith P, Shen E, Edwards LD, Nelsen A, Tapson VF. Inhaled treprostinil and forced vital capacity in patients with interstitial lung disease and associated pulmonary hypertension: a post-hoc analysis of the INCREASE study. The Lancet. Respiratory Medicine. PMID 34214475 DOI: 10.1016/S2213-2600(21)00165-X |
0.486 |
|
| 2021 |
Colebank MJ, Qureshi MU, Rajagopal S, Krasuski RA, Olufsen MS. A multiscale model of vascular function in chronic thromboembolic pulmonary hypertension. American Journal of Physiology. Heart and Circulatory Physiology. PMID 34142886 DOI: 10.1152/ajpheart.00086.2021 |
0.491 |
|
| 2021 |
Wang Z, Rankine L, Bier EA, Mummy D, Lu J, Church A, Tighe RM, Swaminathan A, Huang YT, Que LG, Mammarappallil JG, Rajagopal S, Driehuys B. Using Hyperpolarized Xe Gas Exchange MRI to Model the Regional Airspace, Membrane and Capillary Contributions to Diffusing Capacity. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 33734831 DOI: 10.1152/japplphysiol.00702.2020 |
0.48 |
|
| 2021 |
Tsai CF, Smith JS, Eiger DS, Martin K, Liu T, Smith RD, Shi T, Rajagopal S, Jacobs JM. Mass Spectrometry-Based Proteomics for Analysis of Hydrophilic Phosphopeptides. Methods in Molecular Biology (Clifton, N.J.). 2259: 247-257. PMID 33687720 DOI: 10.1007/978-1-0716-1178-4_16 |
0.791 |
|
| 2021 |
Alenezi F, Rajagopal S. The right atrium, more than a storehouse. International Journal of Cardiology. PMID 33548383 DOI: 10.1016/j.ijcard.2021.01.069 |
0.454 |
|
| 2021 |
Alba GA, Samokhin AO, Wang RS, Zhang YY, Wertheim BM, Arons E, Greenfield EA, Lundberg Slingsby MH, Ceglowski JR, Haley KJ, Bowman FP, Yu YR, Haney JC, Eng G, Mitchell RN, ... Rajagopal S, et al. NEDD9 is a Novel and Modifiable Mediator of Platelet-Endothelial Adhesion in the Pulmonary Circulation. American Journal of Respiratory and Critical Care Medicine. PMID 33523764 DOI: 10.1164/rccm.202003-0719OC |
0.523 |
|
| 2021 |
Smith JS, Pack TF, Inoue A, Lee C, Zheng K, Choi I, Eiger DS, Warman A, Xiong X, Ma Z, Viswanathan G, Levitan IM, Rochelle LK, Staus DP, Snyder JC, ... Rajagopal S, et al. Noncanonical scaffolding of G and β-arrestin by G protein-coupled receptors. Science (New York, N.Y.). PMID 33479120 DOI: 10.1126/science.aay1833 |
0.807 |
|
| 2020 |
Lee C, Viswanathan G, Choi I, Jassal C, Kohlmann T, Rajagopal S. Beta-Arrestins and Receptor Signaling in the Vascular Endothelium. Biomolecules. 11. PMID 33374806 DOI: 10.3390/biom11010009 |
0.652 |
|
| 2020 |
Edmonston DL, Rajagopal S, Wolf M. Echocardiography to Screen for Pulmonary Hypertension in CKD. Kidney International Reports. 5: 2275-2283. PMID 33305121 DOI: 10.1016/j.ekir.2020.09.033 |
0.483 |
|
| 2020 |
Eiger DS, Boldizsar N, Honeycutt CC, Gardner J, Rajagopal S. Biased agonism at chemokine receptors. Cellular Signalling. 78: 109862. PMID 33249087 DOI: 10.1016/j.cellsig.2020.109862 |
0.822 |
|
| 2020 |
Snyder JC, Rajagopal S. Isoforms of GPCR proteins combine for diverse signalling. Nature. PMID 33149314 DOI: 10.1038/d41586-020-03001-0 |
0.605 |
|
| 2020 |
Virgincar RS, Nouls JC, Wang Z, Degan S, Qi Y, Xiong X, Rajagopal S, Driehuys B. Quantitative Xe MRI detects early impairment of gas-exchange in a rat model of pulmonary hypertension. Scientific Reports. 10: 7385. PMID 32355256 DOI: 10.1038/S41598-020-64361-1 |
0.549 |
|
| 2020 |
Yu YA, Malakhau Y, Yu CA, Phelan SJ, Cumming RI, Kan MJ, Mao L, Rajagopal S, Piantadosi CA, Gunn MD. Nonclassical Monocytes Sense Hypoxia, Regulate Pulmonary Vascular Remodeling, and Promote Pulmonary Hypertension. Journal of Immunology (Baltimore, Md. : 1950). PMID 31996456 DOI: 10.4049/Jimmunol.1900239 |
0.561 |
|
| 2020 |
Parikh KS, Doerfler S, Shelburne N, Kennedy K, Whitson J, Dahhan T, Fortin T, Rajagopal S. Experience in Transitioning from Parenteral Prostacyclins to Selexipag in Pulmonary Arterial Hypertension. Journal of Cardiovascular Pharmacology. PMID 31934912 DOI: 10.1097/Fjc.0000000000000800 |
0.552 |
|
| 2020 |
Alenezi F, Rajagopal S, Kutty S. Assessing right atrial function in pulmonary hypertension: window to the soul of the right heart? American Journal of Physiology. Heart and Circulatory Physiology. 318: H154-H155. PMID 31858830 DOI: 10.1152/Ajpheart.00739.2019 |
0.54 |
|
| 2020 |
Zheng K, Smith JS, Choi I, Warman A, Gundry JN, Pack TF, Inoue A, Caron M, Rajagopal S. Biased agonists of the chemokine receptor CXCR3 differentially drive formation of Gαi and β‐arrestin complexes The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03543 |
0.675 |
|
| 2020 |
Lee CY, Decker AM, Xiong X, Viswanathan G, Kohlmann T, Smith JS, Inoue A, Namjoshi OA, Rajagopal S. ACKR3 Regulates Endothelial Cell Function with Non‐canonical Integration of Gαi and β‐arrestin The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03328 |
0.538 |
|
| 2020 |
Eiger DS, Smith J, Tsai C, Jacobs J, Shi T, Rajagopal S. Biased Agonism at CXCR3 Drives Differential Phosphoproteomic and Transcriptomic Profiles and Cellular Outputs The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.00292 |
0.547 |
|
| 2020 |
Arps K, Rajagopal S. Extra Volume: Pulmonary Hypertension Caused By Extra-Cardiac And Intra-Cardiac Shunting Journal of the American College of Cardiology. 75: 2804. DOI: 10.1016/S0735-1097(20)33431-8 |
0.538 |
|
| 2020 |
Suwanpradid J, Lee M, Hoang P, Kwock J, Floyd L, Smith J, Yin Z, Atwater A, Rajagopal S, Kedl R, Corcoran D, MacLeod AS. 014 IL-27 induces IL-15 production to facilitate T cell survival in allergic contact dermatitis Journal of Investigative Dermatology. 140. DOI: 10.1016/J.Jid.2020.03.016 |
0.508 |
|
| 2019 |
Narayanan S, Vasukuttan V, Rajagopal S, Maitra R, Runyon SP. Identification of potent pyrazole based APELIN receptor (APJ) agonists. Bioorganic & Medicinal Chemistry. 115237. PMID 31948845 DOI: 10.1016/J.Bmc.2019.115237 |
0.629 |
|
| 2019 |
Edmonston DL, Parikh KS, Rajagopal S, Shaw LK, Abraham D, Grabner A, Sparks MA, Wolf M. Pulmonary Hypertension Subtypes and Mortality in CKD. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 31732231 DOI: 10.1053/J.Ajkd.2019.08.027 |
0.537 |
|
| 2019 |
Wang Z, Bier EA, Swaminathan A, Parikh K, Nouls J, He M, Mammarappallil JG, Luo S, Driehuys B, Rajagopal S. Diverse Cardiopulmonary Diseases are Associated with Distinct Xenon MRI Signatures. The European Respiratory Journal. PMID 31619473 DOI: 10.1183/13993003.00831-2019 |
0.55 |
|
| 2019 |
Shelburne NJ, Parikh KS, Chiswell K, Shaw LK, Sivak J, Arges K, Tomfohr J, Velazquez EJ, Kisslo J, Samad Z, Rajagopal S. Echocardiographic Assessment of Right Ventricular Function and Response to Therapy in Pulmonary Arterial Hypertension. The American Journal of Cardiology. PMID 31481176 DOI: 10.1016/J.Amjcard.2019.07.026 |
0.54 |
|
| 2019 |
Antonia AL, Gibbs KD, Trahair ED, Pittman KJ, Martin AT, Schott BH, Smith JS, Rajagopal S, Thompson JW, Reinhardt RL, Ko DC. Pathogen Evasion of Chemokine Response Through Suppression of CXCL10. Frontiers in Cellular and Infection Microbiology. 9: 280. PMID 31440475 DOI: 10.3389/Fcimb.2019.00280 |
0.706 |
|
| 2019 |
Tsai CF, Smith J, Krajewski K, Zhao R, Moghieb AM, Nicora CD, Xiong X, Moore RJ, Liu T, Smith RD, Jacobs JM, Rajagopal S, Shi T. TMT labeling facilitates RPLC-MS analysis of hydrophilic phosphopeptides. Analytical Chemistry. PMID 31418558 DOI: 10.1021/Acs.Analchem.9B01814 |
0.688 |
|
| 2019 |
Mamazhakypov A, Viswanathan G, Lawrie A, Schermuly RT, Rajagopal S. The role of chemokines and chemokine receptors in pulmonary arterial hypertension. British Journal of Pharmacology. PMID 31399998 DOI: 10.1111/Bph.14826 |
0.616 |
|
| 2019 |
Benza RL, Doyle M, Lasorda D, Parikh KS, Correa-Jaque P, Badie N, Ginn G, Airhart S, Franco V, Kanwar M, Murali S, Raina A, Agarwal R, Rajagopal S, White J, et al. Monitoring Pulmonary Arterial Hypertension Using an Implantable Hemodynamic Sensor. Chest. PMID 31265832 DOI: 10.1016/J.Chest.2019.06.010 |
0.541 |
|
| 2019 |
Clapham KR, Singh I, Capuano IS, Rajagopal S, Chun HJ. MEF2 and the Right Ventricle: From Development to Disease. Frontiers in Cardiovascular Medicine. 6: 29. PMID 30984767 DOI: 10.3389/Fcvm.2019.00029 |
0.561 |
|
| 2019 |
Parikh KS, Dahhan T, Nicholl L, Ruopp N, Pomann GM, Fortin T, Tapson VF, Rajagopal S. Clinical Features and Outcomes of Patients with Sarcoidosis-associated Pulmonary Hypertension. Scientific Reports. 9: 4061. PMID 30858405 DOI: 10.1038/S41598-019-40030-W |
0.554 |
|
| 2019 |
Suwanpradid J, Hoang P, Kwock J, Floyd L, Smith J, Kedl R, Atwater A, Rajagopal S, Corcoran D, MacLeod A. 010 IL-27 in macrophages mediates T cell survival and dermal cluster formation in allergic contact hypersensitivity Journal of Investigative Dermatology. 139: S2. DOI: 10.1016/J.Jid.2019.03.086 |
0.52 |
|
| 2018 |
Viswanathan G, Mamazhakypov A, Schermuly RT, Rajagopal S. The Role of G Protein-Coupled Receptors in the Right Ventricle in Pulmonary Hypertension. Frontiers in Cardiovascular Medicine. 5: 179. PMID 30619886 DOI: 10.3389/Fcvm.2018.00179 |
0.658 |
|
| 2018 |
Ma Z, Yu YR, Badea CT, Kovacs JJ, Xiong X, Comhair S, Piantadosi CA, Rajagopal S. Vascular Endothelial Growth Factor Receptor 3 Regulates Endothelial Function Through β-Arrestin 1. Circulation. PMID 30586762 DOI: 10.1161/Circulationaha.118.034961 |
0.809 |
|
| 2018 |
Alenezi F, Mandawat A, Il'Giovine ZJ, Shaw LK, Siddiqui I, Tapson VF, Arges K, Rivera D, Romano MMD, Velazquez EJ, Douglas PS, Samad Z, Rajagopal S. Clinical Utility and Prognostic Value of Right Atrial Function in Pulmonary Hypertension. Circulation. Cardiovascular Imaging. 11: e006984. PMID 30571314 DOI: 10.1161/Circimaging.117.006984 |
0.533 |
|
| 2018 |
Rajarathnam K, Schnoor M, Richardson RM, Rajagopal S. How do chemokines navigate neutrophils to the target site: Dissecting the structural mechanisms and signaling pathways. Cellular Signalling. PMID 30465827 DOI: 10.1016/J.Cellsig.2018.11.004 |
0.695 |
|
| 2018 |
Bier EA, Robertson SH, Schrank GM, Rackley C, Mammarappallil JG, Rajagopal S, McAdams HP, Driehuys B. A protocol for quantifying cardiogenic oscillations in dynamic Xe gas exchange spectroscopy: The effects of idiopathic pulmonary fibrosis. Nmr in Biomedicine. e4029. PMID 30457202 DOI: 10.1002/Nbm.4029 |
0.537 |
|
| 2018 |
Ghadimi K, Rajagopal S. Nasally Inhaled Nitric Oxide for Sudden Right-Sided Heart Failure in the Intensive Care Unit: NO Time Like the Present. Journal of Cardiothoracic and Vascular Anesthesia. PMID 30420312 DOI: 10.1053/J.Jvca.2018.10.008 |
0.517 |
|
| 2018 |
Smith JS, Nicholson LT, Suwanpradid J, Glenn RA, Knape NM, Alagesan P, Gundry JN, Wehrman TS, Atwater AR, Gunn MD, MacLeod AS, Rajagopal S. Biased agonists of the chemokine receptor CXCR3 differentially control chemotaxis and inflammation. Science Signaling. 11. PMID 30401786 DOI: 10.1126/Scisignal.Aaq1075 |
0.76 |
|
| 2018 |
Luttrell LM, Wang J, Plouffe B, Smith JS, Yamani L, Kaur S, Jean-Charles PY, Gauthier C, Lee MH, Pani B, Kim J, Ahn S, Rajagopal S, Reiter E, Bouvier M, et al. Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9. Science Signaling. 11. PMID 30254056 DOI: 10.1126/Scisignal.Aat7650 |
0.812 |
|
| 2018 |
Siddiqui I, Rajagopal S, Brucker A, Chiswell K, Christopher B, Alenezi F, Mandawat A, Rivera D, Arges K, Tapson V, Kisslo J, Velazquez E, Douglas PS, Samad Z. Clinical and Echocardiographic Predictors of Outcomes in Patients With Pulmonary Hypertension. The American Journal of Cardiology. PMID 30093068 DOI: 10.1016/J.Amjcard.2018.05.019 |
0.537 |
|
| 2018 |
Wang Z, He M, Bier E, Rankine L, Schrank G, Rajagopal S, Huang YC, Kelsey C, Womack S, Mammarappallil J, Driehuys B. Hyperpolarized Xe gas transfer MRI: the transition from 1.5T to 3T. Magnetic Resonance in Medicine. PMID 30024058 DOI: 10.1002/Mrm.27377 |
0.523 |
|
| 2018 |
Loyalka P, Ansari MZ, Cheema FH, Miller CC, Rajagopal S, Rajagopal K. Surgical pulmonary embolectomy and catheter-based therapies for acute pulmonary embolism: A contemporary systematic review. The Journal of Thoracic and Cardiovascular Surgery. PMID 30005883 DOI: 10.1016/J.Jtcvs.2018.05.085 |
0.672 |
|
| 2018 |
Smith JS, Rajagopal S, Atwater AR. Chemokine Signaling in Allergic Contact Dermatitis: Toward Targeted Therapies. Dermatitis : Contact, Atopic, Occupational, Drug. PMID 29939854 DOI: 10.1097/Der.0000000000000391 |
0.748 |
|
| 2018 |
Il'Giovine ZJ, Mulder H, Chiswell K, Arges K, Tomfohr J, Hashmi A, Velazquez EJ, Kisslo JA, Samad Z, Rajagopal S. Right Ventricular Longitudinal Strain Reproducibility Using Vendor-Dependent and Vendor-Independent Software. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. PMID 29525250 DOI: 10.1016/J.Echo.2018.01.008 |
0.537 |
|
| 2018 |
Smith JS, Lefkowitz RJ, Rajagopal S. Biased signalling: from simple switches to allosteric microprocessors. Nature Reviews. Drug Discovery. PMID 29302067 DOI: 10.1038/Nrd.2017.229 |
0.798 |
|
| 2017 |
Luo N, Craig D, Ilkayeva O, Muehlbauer M, Kraus WE, Newgard CB, Shah SH, Rajagopal S. Plasma acylcarnitines are associated with pulmonary hypertension. Pulmonary Circulation. 7: 211-218. PMID 28680580 DOI: 10.1086/690554 |
0.53 |
|
| 2017 |
Parikh KS, Rao Y, Ahmad T, Shen K, Felker GM, Rajagopal S. Novel approach to classifying patients with pulmonary arterial hypertension using cluster analysis. Pulmonary Circulation. 7: 486-493. PMID 28597780 DOI: 10.1177/2045893217705891 |
0.522 |
|
| 2017 |
Smith JS, Alagesan P, Desai NK, Pack TF, Wu JH, Inoue A, Freedman NJ, Rajagopal S. C-X-C Motif Chemokine Receptor 3 Splice Variants Differentially Activate Beta-Arrestins to Regulate Downstream Signaling Pathways. Molecular Pharmacology. PMID 28559424 DOI: 10.1124/Mol.117.108522 |
0.827 |
|
| 2017 |
Wang Z, Robertson SH, Wang J, He M, Virgincar RS, Schrank GM, Bier EA, Rajagopal S, Huang YC, O'Riordan TG, Rackley CR, McAdams HP, Driehuys B. Quantitative Analysis of Hyperpolarized (129) Xe Gas Transfer MRI. Medical Physics. PMID 28382694 DOI: 10.1002/Mp.12264 |
0.529 |
|
| 2017 |
Broderick-Forsgren K, Davenport CA, Sivak JA, Hargett CW, Foster MC, Monteagudo A, Armour A, Rajagopal S, Arges K, Velazquez EJ, Samad Z. Improving on the diagnostic characteristics of echocardiography for pulmonary hypertension. The International Journal of Cardiovascular Imaging. PMID 28337558 DOI: 10.1007/S10554-017-1114-2 |
0.542 |
|
| 2017 |
Onaran HO, Ambrosio C, Uğur Ö, Madaras Koncz E, Grò MC, Vezzi V, Rajagopal S, Costa T. Systematic errors in detecting biased agonism: Analysis of current methods and development of a new model-free approach. Scientific Reports. 7: 44247. PMID 28290478 DOI: 10.1038/Srep44247 |
0.642 |
|
| 2017 |
Dahhan T, Alenezi F, Samad Z, Rajagopal S. Echocardiography in the Risk Assessment of Acute Pulmonary Embolism. Seminars in Respiratory and Critical Care Medicine. 38: 18-28. PMID 28208195 DOI: 10.1055/S-0036-1597563 |
0.538 |
|
| 2017 |
Gundry J, Glenn R, Alagesan P, Rajagopal S. A Practical Guide to Approaching Biased Agonism at G Protein Coupled Receptors. Frontiers in Neuroscience. 11: 17. PMID 28174517 DOI: 10.3389/Fnins.2017.00017 |
0.676 |
|
| 2017 |
Rajagopal S, Shenoy SK. GPCR desensitization: Acute and prolonged phases. Cellular Signalling. PMID 28137506 DOI: 10.1016/J.Cellsig.2017.01.024 |
0.793 |
|
| 2017 |
Smith J, Nicholson L, Suwanpradid J, Glenn R, Gundry J, Alagesan P, Knape N, Atwater A, Gunn M, MacLeod A, Lefkowitz R, Rajagopal S. 678 Biased CXCR3 ligands differentially alter allergic contact hypersensitivity and chemotaxis Journal of Investigative Dermatology. 137: S117. DOI: 10.1016/J.Jid.2017.02.701 |
0.624 |
|
| 2016 |
Dahhan T, Siddiqui I, Tapson VF, Velazquez EJ, Sun S, Davenport CA, Samad Z, Rajagopal S. Clinical and echocardiographic predictors of mortality in acute pulmonary embolism. Cardiovascular Ultrasound. 14: 44. PMID 27793158 DOI: 10.1186/S12947-016-0087-Y |
0.535 |
|
| 2016 |
Ma Z, Mao L, Rajagopal S. Hemodynamic Characterization of Rodent Models of Pulmonary Arterial Hypertension. Journal of Visualized Experiments : Jove. PMID 27167679 DOI: 10.3791/53335 |
0.55 |
|
| 2016 |
Dahhan T, Kaushik SS, He M, Mammarappallil JG, Tapson VF, McAdams HP, Sporn TA, Driehuys B, Rajagopal S. Abnormalities in hyperpolarized (129)Xe magnetic resonance imaging and spectroscopy in two patients with pulmonary vascular disease. Pulmonary Circulation. 6: 126-31. PMID 27162620 DOI: 10.1086/685110 |
0.536 |
|
| 2016 |
Smith JS, Rajagopal S. The β-arrestins: Multifunctional regulators of G protein-coupled receptors. The Journal of Biological Chemistry. PMID 26984408 DOI: 10.1074/Jbc.R115.713313 |
0.77 |
|
| 2016 |
Parikh KS, Rajagopal S, Fortin T, Tapson VF, Poms AD. Safety and Tolerability of High-dose Inhaled Treprostinil in Pulmonary Hypertension. Journal of Cardiovascular Pharmacology. PMID 26828324 DOI: 10.1097/Fjc.0000000000000357 |
0.543 |
|
| 2015 |
Forsha D, Risum N, Rajagopal S, Dolgner S, Hornik C, Barnhart H, Kisslo J, Barker P. The influence of angle of insonation and target depth on speckle-tracking strain. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 28: 580-6. PMID 25655402 DOI: 10.1016/J.Echo.2014.12.015 |
0.516 |
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| 2015 |
Parikh KS, Rajagopal S, Arges K, Ahmad T, Sivak J, Kaul P, Shah SH, Tapson V, Velazquez EJ, Douglas PS, Samad Z. Use of outcome measures in pulmonary hypertension clinical trials American Heart Journal. DOI: 10.1016/j.ahj.2015.06.010 |
0.476 |
|
| 2014 |
Onaran HO, Rajagopal S, Costa T. What is biased efficacy? Defining the relationship between intrinsic efficacy and free energy coupling. Trends in Pharmacological Sciences. 35: 639-47. PMID 25448316 DOI: 10.1016/J.Tips.2014.09.010 |
0.66 |
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| 2014 |
Kahsai AW, Rajagopal S, Sun J, Xiao K. Monitoring protein conformational changes and dynamics using stable-isotope labeling and mass spectrometry. Nature Protocols. 9: 1301-19. PMID 24810039 DOI: 10.1038/Nprot.2014.075 |
0.707 |
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| 2014 |
Rajagopal S, Forsha DE, Risum N, Hornik CP, Poms AD, Fortin TA, Tapson VF, Velazquez EJ, Kisslo J, Samad Z. Comprehensive assessment of right ventricular function in patients with pulmonary hypertension with global longitudinal peak systolic strain derived from multiple right ventricular views. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 27: 657-665.e3. PMID 24656881 DOI: 10.1016/J.Echo.2014.02.001 |
0.547 |
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| 2014 |
Forsha D, Risum N, Kropf PA, Rajagopal S, Smith PB, Kanter RJ, Samad Z, Sogaard P, Barker P, Kisslo J. Right ventricular mechanics using a novel comprehensive three-view echocardiographic strain analysis in a normal population. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 27: 413-22. PMID 24508364 DOI: 10.1016/J.Echo.2013.12.018 |
0.529 |
|
| 2014 |
Rajagopal S, Bassoni D, Campbell J, Gerard N, Gerard C, Wehrman T. Understanding the mechanism of biased agonism at chemokine receptors (1066.17) The Faseb Journal. 28. DOI: 10.1096/Fasebj.28.1_Supplement.1066.17 |
0.671 |
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| 2014 |
Krishnamoorthy A, Vakamudi S, Watson MH, Byrns JS, Rajagopal S, Felker GM, Rogers JG, Patel CB. Hemodynamic Response to Continuous Outpatient Milrinone Infusion in Advanced Heart Failure Patients with Mixed Pulmonary Hypertension Journal of Cardiac Failure. 20. DOI: 10.1016/J.Cardfail.2014.06.118 |
0.537 |
|
| 2013 |
Rajagopal S, Bassoni DL, Campbell JJ, Gerard NP, Gerard C, Wehrman TS. Biased agonism as a mechanism for differential signaling by chemokine receptors. The Journal of Biological Chemistry. 288: 35039-48. PMID 24145037 DOI: 10.1074/Jbc.M113.479113 |
0.697 |
|
| 2013 |
Rajagopal S. Quantifying biased agonism: understanding the links between affinity and efficacy. Nature Reviews. Drug Discovery. 12: 483. PMID 23681006 DOI: 10.1038/Nrd3954-C1 |
0.538 |
|
| 2012 |
Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, et al. Global phosphorylation analysis of β-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR) (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 34 (15299-15304) doi:10.1073/pnas.1008461107) Proceedings of the National Academy of Sciences of the United States of America. 109: 13464. DOI: 10.1073/Pnas.1211889109 |
0.794 |
|
| 2011 |
Nobles KN, Xiao K, Ahn S, Shukla AK, Lam CM, Rajagopal S, Strachan RT, Huang TY, Bressler EA, Hara MR, Shenoy SK, Gygi SP, Lefkowitz RJ. Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin. Science Signaling. 4: ra51. PMID 21868357 DOI: 10.1126/Scisignal.2001707 |
0.78 |
|
| 2011 |
Hara MR, Kovacs JJ, Whalen EJ, Rajagopal S, Strachan RT, Grant W, Towers AJ, Williams B, Lam CM, Xiao K, Shenoy SK, Gregory SG, Ahn S, Duckett DR, Lefkowitz RJ. A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1. Nature. 477: 349-53. PMID 21857681 DOI: 10.1038/Nature10368 |
0.755 |
|
| 2011 |
Kahsai AW, Xiao K, Rajagopal S, Ahn S, Shukla AK, Sun J, Oas TG, Lefkowitz RJ. Multiple ligand-specific conformations of the β2-adrenergic receptor. Nature Chemical Biology. 7: 692-700. PMID 21857662 DOI: 10.1038/Nchembio.634 |
0.828 |
|
| 2011 |
Rajagopal S, Ahn S, Rominger DH, Gowen-MacDonald W, Lam CM, Dewire SM, Violin JD, Lefkowitz RJ. Quantifying ligand bias at seven-transmembrane receptors. Molecular Pharmacology. 80: 367-77. PMID 21610196 DOI: 10.1124/Mol.111.072801 |
0.816 |
|
| 2011 |
Whalen EJ, Rajagopal S, Lefkowitz RJ. Therapeutic potential of β-arrestin- and G protein-biased agonists. Trends in Molecular Medicine. 17: 126-39. PMID 21183406 DOI: 10.1016/J.Molmed.2010.11.004 |
0.815 |
|
| 2011 |
Rajagopal S, Kovacs J, Badea C, Johnson GA, Rockman HA, Piantadosi CA, Lefkowitz RJ. BETA-ARRESTINS REGULATE SIGNALING BY BONE MORPHOGENETIC PROTEIN TYPE II RECEPTOR IN PULMONARY ARTERIAL HYPERTENSION Journal of the American College of Cardiology. 57: E2046. DOI: 10.1016/S0735-1097(11)62046-9 |
0.674 |
|
| 2010 |
Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, et al. Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR). Proceedings of the National Academy of Sciences of the United States of America. 107: 15299-304. PMID 20686112 DOI: 10.1073/Pnas.1008461107 |
0.794 |
|
| 2010 |
Rajagopal S, Rajagopal K, Lefkowitz RJ. Teaching old receptors new tricks: biasing seven-transmembrane receptors. Nature Reviews. Drug Discovery. 9: 373-86. PMID 20431569 DOI: 10.1038/Nrd3024 |
0.8 |
|
| 2010 |
Rajagopal S, Kim J, Ahn S, Craig S, Lam CM, Gerard NP, Gerard C, Lefkowitz RJ. Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7. Proceedings of the National Academy of Sciences of the United States of America. 107: 628-32. PMID 20018651 DOI: 10.1073/Pnas.0912852107 |
0.776 |
|
| 2007 |
Rajagopal S, Kent SB. Total chemical synthesis and biophysical characterization of the minimal isoform of the KChIP2 potassium channel regulatory subunit. Protein Science : a Publication of the Protein Society. 16: 2056-64. PMID 17660260 DOI: 10.1110/Ps.072876107 |
0.541 |
|
| 2005 |
Ihee H, Rajagopal S, Srajer V, Pahl R, Anderson S, Schmidt M, Schotte F, Anfinrud PA, Wulff M, Moffat K. Visualizing reaction pathways in photoactive yellow protein from nanoseconds to seconds. Proceedings of the National Academy of Sciences of the United States of America. 102: 7145-50. PMID 15870207 DOI: 10.1073/Pnas.0409035102 |
0.788 |
|
| 2005 |
Rajagopal S, Anderson S, Srajer V, Schmidt M, Pahl R, Moffat K. A structural pathway for signaling in the E46Q mutant of photoactive yellow protein. Structure (London, England : 1993). 13: 55-63. PMID 15642261 DOI: 10.1016/J.Str.2004.10.016 |
0.772 |
|
| 2005 |
Moffat K, Anderson S, Rajagopal S, Srajer V, Pahl R, Ihee H, Schmidt M, Key J. How do signaling photoreceptors respond to light? Acta Crystallographica Section a Foundations of Crystallography. 61: c72-c72. DOI: 10.1107/S0108767305096947 |
0.773 |
|
| 2004 |
Rajagopal S, Key JM, Purcell EB, Boerema DJ, Moffat K. Purification and initial characterization of a putative blue light-regulated phosphodiesterase from Escherichia coli. Photochemistry and Photobiology. 80: 542-7. PMID 15453820 DOI: 10.1562/0031-8655(2004)080<0542:Paicoa>2.0.Co;2 |
0.744 |
|
| 2004 |
Rajagopal S, Kostov KS, Moffat K. Analytical trapping: extraction of time-independent structures from time-dependent crystallographic data. Journal of Structural Biology. 147: 211-22. PMID 15450291 DOI: 10.1016/J.Jsb.2004.04.007 |
0.657 |
|
| 2004 |
Anderson S, Srajer V, Pahl R, Rajagopal S, Schotte F, Anfinrud P, Wulff M, Moffat K. Chromophore conformation and the evolution of tertiary structural changes in photoactive yellow protein. Structure (London, England : 1993). 12: 1039-45. PMID 15274923 DOI: 10.1016/J.Str.2004.04.008 |
0.751 |
|
| 2004 |
Rajagopal S, Schmidt M, Anderson S, Ihee H, Moffat K. Analysis of experimental time-resolved crystallographic data by singular value decomposition. Acta Crystallographica. Section D, Biological Crystallography. 60: 860-71. PMID 15103131 DOI: 10.1107/S0907444904004160 |
0.771 |
|
| 2004 |
Schmidt M, Pahl R, Srajer V, Anderson S, Ren Z, Ihee H, Rajagopal S, Moffat K. Protein kinetics: structures of intermediates and reaction mechanism from time-resolved x-ray data. Proceedings of the National Academy of Sciences of the United States of America. 101: 4799-804. PMID 15041745 DOI: 10.1073/Pnas.0305983101 |
0.767 |
|
| 2004 |
Schmidt M, Rajagopal S, Anderson S, Moffat K. Protein kinetics: relaxations on atomic length scales Acta Crystallographica Section a Foundations of Crystallography. 60: s19-s19. DOI: 10.1107/S0108767304099647 |
0.723 |
|
| 2003 |
Schmidt M, Rajagopal S, Ren Z, Moffat K. Application of singular value decomposition to the analysis of time-resolved macromolecular x-ray data. Biophysical Journal. 84: 2112-29. PMID 12609912 DOI: 10.1016/S0006-3495(03)75018-8 |
0.661 |
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| 2003 |
Rajagopal S, Moffat K. Crystal structure of a photoactive yellow protein from a sensor histidine kinase: conformational variability and signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 100: 1649-54. PMID 12563032 DOI: 10.1073/Pnas.0336353100 |
0.696 |
|
| 2003 |
Crosson S, Rajagopal S, Moffat K. The LOV domain family: photoresponsive signaling modules coupled to diverse output domains. Biochemistry. 42: 2-10. PMID 12515534 DOI: 10.1021/Bi026978L |
0.74 |
|
| 2002 |
Schmidt M, Pahl R, Srajer V, Anderson S, Brister K, Ruan S, Rajagopal S, Ren Z, Moffat K. Application of singular value decomposition to time-resolved X-ray data; simulations and experiments Acta Crystallographica Section a Foundations of Crystallography. 58: c374-c374. DOI: 10.1107/S0108767302099956 |
0.709 |
|
| 2002 |
Moffat K, Srajer V, Pahl R, Ren Z, Schmidt M, Anderson S, Crosson S, Perman B, Rajagopal S, Ihee H, Bourgeois D, Wulff M. Time-resolved macromolecular crystallography: molecular movies? Acta Crystallographica Section a Foundations of Crystallography. 58: c27-c27. DOI: 10.1107/S0108767302086166 |
0.751 |
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