Zhaolan Zhou, Ph.D. - Publications

Harvard University, Cambridge, MA, United States 
Gene Regulation

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Connolly DR, Zhou Z. Genomic insights into MeCP2 function: A role for the maintenance of chromatin architecture. Current Opinion in Neurobiology. 59: 174-179. PMID 31430649 DOI: 10.1016/J.Conb.2019.07.002  0.359
2019 Tang S, Terzic B, Wang IJ, Sarmiento N, Sizov K, Cui Y, Takano H, Marsh ED, Zhou Z, Coulter DA. Altered NMDAR signaling underlies autistic-like features in mouse models of CDKL5 deficiency disorder. Nature Communications. 10: 2655. PMID 31201320 DOI: 10.1038/S41467-019-10689-W  0.306
2018 Zhao YT, Kwon DY, Johnson BS, Fasolino M, Lamonica JM, Kim YJ, Zhao BS, He C, Vahedi G, Kim TH, Zhou Z. Long genes linked to autism spectrum disorders harbor broad enhancer-like chromatin domains. Genome Research. PMID 29848492 DOI: 10.1101/Gr.233775.117  0.407
2018 Gulinello M, Mitchell HA, Chang Q, Timothy O'Brien W, Zhou Z, Abel T, Wang L, Corbin JG, Veeraragavan S, Samaco RC, Andrews NA, Fagiolini M, Cole TB, Burbacher TM, Crawley JN. Rigor and Reproducibility in Rodent Behavioral Research. Neurobiology of Learning and Memory. PMID 29307548 DOI: 10.1016/J.Nlm.2018.01.001  0.373
2017 Hu P, Fabyanic E, Kwon DY, Tang S, Zhou Z, Wu H. Dissecting Cell-Type Composition and Activity-Dependent Transcriptional State in Mammalian Brains by Massively Parallel Single-Nucleus RNA-Seq. Molecular Cell. 68: 1006-1015.e7. PMID 29220646 DOI: 10.1016/J.Molcel.2017.11.017  0.318
2017 Iwase S, Bérubé NG, Zhou Z, Kasri NN, Battaglioli E, Scandaglia M, Barco A. Epigenetic Etiology of Intellectual Disability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 10773-10782. PMID 29118205 DOI: 10.1523/Jneurosci.1840-17.2017  0.345
2017 Johnson BS, Zhao YT, Fasolino M, Lamonica JM, Kim YJ, Georgakilas G, Wood KH, Bu D, Cui Y, Goffin D, Vahedi G, Kim TH, Zhou Z. Biotin tagging of MeCP2 in mice reveals contextual insights into the Rett syndrome transcriptome. Nature Medicine. PMID 28920956 DOI: 10.1038/Nm.4406  0.424
2017 Tang S, Wang IJ, Yue C, Takano H, Terzic B, Pance K, Lee JY, Cui Y, Coulter DA, Zhou Z. Loss of CDKL5 in glutamatergic neurons disrupts hippocampal microcircuitry and leads to memory impairment in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28674172 DOI: 10.1523/Jneurosci.0539-17.2017  0.3
2017 Fasolino M, Zhou Z. The Crucial Role of DNA Methylation and MeCP2 in Neuronal Function. Genes. 8. PMID 28505093 DOI: 10.3390/Genes8050141  0.314
2017 Lamonica JM, Kwon DY, Goffin D, Fenik P, Johnson BS, Cui Y, Guo H, Veasey S, Zhou Z. Elevating expression of MeCP2 T158M rescues DNA binding and Rett syndrome-like phenotypes. The Journal of Clinical Investigation. PMID 28394263 DOI: 10.1172/Jci90967  0.344
2016 Wood KH, Zhou Z. Emerging Molecular and Biological Functions of MBD2, a Reader of DNA Methylation. Frontiers in Genetics. 7: 93. PMID 27303433 DOI: 10.3389/Fgene.2016.00093  0.358
2016 Wood KH, Johnson BS, Welsh SA, Lee JY, Cui Y, Krizman E, Brodkin ES, Blendy JA, Robinson MB, Bartolomei MS, Zhou Z. Tagging methyl-CpG-binding domain proteins reveals different spatiotemporal expression and supports distinct functions. Epigenomics. PMID 27066839 DOI: 10.2217/Epi-2015-0004  0.331
2013 Zhao YT, Goffin D, Johnson BS, Zhou Z. Loss of MeCP2 function is associated with distinct gene expression changes in the striatum. Neurobiology of Disease. 59: 257-66. PMID 23948639 DOI: 10.1016/J.Nbd.2013.08.001  0.346
2013 Wang IT, Reyes AR, Zhou Z. Neuronal morphology in MeCP2 mouse models is intrinsically variable and depends on age, cell type, and Mecp2 mutation. Neurobiology of Disease. 58: 3-12. PMID 23659895 DOI: 10.1016/J.Nbd.2013.04.020  0.348
2012 Wang IT, Allen M, Goffin D, Zhu X, Fairless AH, Brodkin ES, Siegel SJ, Marsh ED, Blendy JA, Zhou Z. Loss of CDKL5 disrupts kinome profile and event-related potentials leading to autistic-like phenotypes in mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 21516-21. PMID 23236174 DOI: 10.1073/Pnas.1216988110  0.314
2012 Goffin D, Allen M, Zhang L, Amorim M, Wang IT, Reyes AR, Mercado-Berton A, Ong C, Cohen S, Hu L, Blendy JA, Carlson GC, Siegel SJ, Greenberg ME, Zhou Z. Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses. Nature Neuroscience. 15: 274-83. PMID 22119903 DOI: 10.1038/Nn.2997  0.32
2011 Cohen S, Gabel HW, Hemberg M, Hutchinson AN, Sadacca LA, Ebert DH, Harmin DA, Greenberg RS, Verdine VK, Zhou Z, Wetsel WC, West AE, Greenberg ME. Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function. Neuron. 72: 72-85. PMID 21982370 DOI: 10.1016/J.Neuron.2011.08.022  0.326
2009 Bracaglia G, Conca B, Bergo A, Rusconi L, Zhou Z, Greenberg ME, Landsberger N, Soddu S, Kilstrup-Nielsen C. Methyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosis. Embo Reports. 10: 1327-33. PMID 19820693 DOI: 10.1038/Embor.2009.217  0.318
2009 Wood L, Gray NW, Zhou Z, Greenberg ME, Shepherd GM. Synaptic circuit abnormalities of motor-frontal layer 2/3 pyramidal neurons in an RNA interference model of methyl-CpG-binding protein 2 deficiency. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12440-8. PMID 19812320 DOI: 10.1523/Jneurosci.3321-09.2009  0.301
2006 Zhou Z, Hong EJ, Cohen S, Zhao WN, Ho HY, Schmidt L, Chen WG, Lin Y, Savner E, Griffith EC, Hu L, Steen JA, Weitz CJ, Greenberg ME. Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation. Neuron. 52: 255-69. PMID 17046689 DOI: 10.1016/J.Neuron.2006.09.037  0.343
2003 Zhou Z, Reed R. Purification of functional RNA-protein complexes using MS2-MBP. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 27.3. PMID 18265330 DOI: 10.1002/0471142727.Mb2703S63  0.5
2002 Zhou Z, Licklider LJ, Gygi SP, Reed R. Comprehensive proteomic analysis of the human spliceosome. Nature. 419: 182-5. PMID 12226669 DOI: 10.1038/Nature01031  0.527
2002 Zhou Z, Sim J, Griffith J, Reed R. Purification and electron microscopic visualization of functional human spliceosomes. Proceedings of the National Academy of Sciences of the United States of America. 99: 12203-7. PMID 12215496 DOI: 10.1073/Pnas.182427099  0.492
2002 Chung S, Zhou Z, Huddleston KA, Harrison DA, Reed R, Coleman TA, Rymond BC. Crooked neck is a component of the human spliceosome and implicated in the splicing process. Biochimica Et Biophysica Acta. 1576: 287-97. PMID 12084575 DOI: 10.1016/S0167-4781(02)00368-8  0.528
2001 Luo ML, Zhou Z, Magni K, Christoforides C, Rappsilber J, Mann M, Reed R. Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly. Nature. 413: 644-7. PMID 11675789 DOI: 10.1038/35098106  0.513
2001 Clouse KN, Luo MJ, Zhou Z, Reed R. A Ran-independent pathway for export of spliced mRNA. Nature Cell Biology. 3: 97-9. PMID 11146633 DOI: 10.1038/35050625  0.494
2000 Zhou Z, Luo MJ, Straesser K, Katahira J, Hurt E, Reed R. The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans. Nature. 407: 401-5. PMID 11014198 DOI: 10.1038/35030160  0.51
2000 Das R, Zhou Z, Reed R. Functional association of U2 snRNP with the ATP-independent spliceosomal complex E. Molecular Cell. 5: 779-87. PMID 10882114 DOI: 10.1016/S1097-2765(00)80318-4  0.457
1998 Zhou Z, Reed R. Human homologs of yeast prp16 and prp17 reveal conservation of the mechanism for catalytic step II of pre-mRNA splicing. The Embo Journal. 17: 2095-106. PMID 9524131 DOI: 10.1093/Emboj/17.7.2095  0.501
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