Year |
Citation |
Score |
2023 |
Crompton LA, McComish SF, Steward TGJ, Whitcomb DJ, Lane JD, Caldwell MA. Human stem cell-derived ventral midbrain astrocytes exhibit a region-specific secretory profile. Brain Communications. 5: fcad114. PMID 37124945 DOI: 10.1093/braincomms/fcad114 |
0.319 |
|
2021 |
Crompton LA, McComish SF, Stathakos P, Cordero-Llana O, Lane JD, Caldwell MA. Efficient and Scalable Generation of Human Ventral Midbrain Astrocytes from Human-Induced Pluripotent Stem Cells. Journal of Visualized Experiments : Jove. PMID 34661566 DOI: 10.3791/62095 |
0.779 |
|
2021 |
MacMahon Copas AN, McComish SF, Fletcher JM, Caldwell MA. The Pathogenesis of Parkinson's Disease: A Complex Interplay Between Astrocytes, Microglia, and T Lymphocytes? Frontiers in Neurology. 12: 666737. PMID 34122308 DOI: 10.3389/fneur.2021.666737 |
0.32 |
|
2020 |
Stathakos P, Jiménez-Moreno N, Crompton LA, Nistor PA, Badger JL, Barbuti PA, Kerrigan TL, Randall AD, Caldwell MA, Lane JD. A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons. Autophagy. 1-17. PMID 32286126 DOI: 10.1080/15548627.2020.1739441 |
0.486 |
|
2019 |
Stathakos P, Jimenez-Moreno N, Crompton L, Nistor P, Caldwell MA, Lane JD. Imaging Autophagy in hiPSC-Derived Midbrain Dopaminergic Neuronal Cultures for Parkinson's Disease Research. Methods in Molecular Biology (Clifton, N.J.). 1880: 257-280. PMID 30610703 DOI: 10.1007/978-1-4939-8873-0_17 |
0.51 |
|
2018 |
Kelly CM, Caldwell MA. Derivation of Neural Stem Cells from the Developing and Adult Human Brain. Results and Problems in Cell Differentiation. 66: 3-20. PMID 30209653 DOI: 10.1007/978-3-319-93485-3_1 |
0.339 |
|
2018 |
McComish SF, Caldwell MA. Generation of defined neural populations from pluripotent stem cells. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29786550 DOI: 10.1098/rstb.2017.0214 |
0.36 |
|
2018 |
Hawkins SJ, Crompton LA, Sood A, Saunders M, Boyle NT, Buckley A, Minogue AM, McComish SF, Jiménez-Moreno N, Cordero-Llana O, Stathakos P, Gilmore CE, Kelly S, Lane JD, Case CP, ... Caldwell MA, et al. Nanoparticle-induced neuronal toxicity across placental barriers is mediated by autophagy and dependent on astrocytes. Nature Nanotechnology. PMID 29610530 DOI: 10.1038/S41565-018-0085-3 |
0.742 |
|
2017 |
McMillan KJ, Murray TK, Bengoa-Vergniory N, Cordero-Llana O, Cooper J, Buckley A, Wade-Martins R, Uney JB, O'Neill MJ, Wong LF, Caldwell MA. Loss of MicroRNA-7 Regulation Leads to α-Synuclein Accumulation and Dopaminergic Neuronal Loss In Vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28927576 DOI: 10.1016/J.Ymthe.2017.08.017 |
0.731 |
|
2017 |
Jiménez-Moreno N, Stathakos P, Caldwell MA, Lane JD. Induced Pluripotent Stem Cell Neuronal Models for the Study of Autophagy Pathways in Human Neurodegenerative Disease. Cells. 6. PMID 28800101 DOI: 10.3390/cells6030024 |
0.413 |
|
2017 |
Crompton LA, Cordero-Llana O, Caldwell MA. Astrocytes in a dish: Using pluripotent stem cells to model neurodegenerative and neurodevelopmental disorders. Brain Pathology (Zurich, Switzerland). 27: 530-544. PMID 28585380 DOI: 10.1111/Bpa.12522 |
0.774 |
|
2016 |
Zhu B, Caldwell M, Song B. Development of stem cell-based therapies for Parkinson's disease. The International Journal of Neuroscience. 1-13. PMID 26824870 DOI: 10.3109/00207454.2016.1148034 |
0.409 |
|
2015 |
Nistor PA, May PW, Tamagnini F, Randall AD, Caldwell MA. Long-term culture of pluripotent stem-cell-derived human neurons on diamond--A substrate for neurodegeneration research and therapy. Biomaterials. 61: 139-49. PMID 26002787 DOI: 10.1016/J.Biomaterials.2015.04.050 |
0.393 |
|
2015 |
Cordero-Llana Ó, Houghton BC, Rinaldi F, Taylor H, Yáñez-Muñoz RJ, Uney JB, Wong LF, Caldwell MA. Enhanced efficacy of the CDNF/MANF family by combined intranigral overexpression in the 6-OHDA rat model of Parkinson's disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 244-54. PMID 25369767 DOI: 10.1038/Mt.2014.206 |
0.736 |
|
2015 |
Nistor PA, May PW, Tamagnini F, Randall AD, Caldwell MA. Long-term culture of pluripotent stem-cell-derived human neurons on diamond - A substrate for neurodegeneration research and therapy Biomaterials. 61: 139-149. DOI: 10.1016/j.biomaterials.2015.04.050 |
0.353 |
|
2014 |
Cordero-Llana O, Rinaldi F, Brennan PA, Wynick D, Caldwell MA. Galanin promotes neuronal differentiation from neural progenitor cells in vitro and contributes to the generation of new olfactory neurons in the adult mouse brain. Experimental Neurology. 256: 93-104. PMID 24726665 DOI: 10.1016/J.Expneurol.2014.04.001 |
0.775 |
|
2014 |
Rinaldi F, Hartfield EM, Crompton LA, Badger JL, Glover CP, Kelly CM, Rosser AE, Uney JB, Caldwell MA. Cross-regulation of Connexin43 and β-catenin influences differentiation of human neural progenitor cells. Cell Death & Disease. 5: e1017. PMID 24457961 DOI: 10.1038/Cddis.2013.546 |
0.387 |
|
2013 |
Rinaldi F, Caldwell MA. Modeling astrocytic contribution toward neurodegeneration with pluripotent stem cells: focus on Alzheimer's and Parkinson's diseases. Neuroreport. 24: 1053-7. PMID 24201446 DOI: 10.1097/WNR.0000000000000064 |
0.381 |
|
2013 |
Crompton LA, Byrne ML, Taylor H, Kerrigan TL, Bru-Mercier G, Badger JL, Barbuti PA, Jo J, Tyler SJ, Allen SJ, Kunath T, Cho K, Caldwell MA. Stepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signaling. Stem Cell Research. 11: 1206-21. PMID 24013066 DOI: 10.1016/J.Scr.2013.08.002 |
0.401 |
|
2012 |
Badger JL, Byrne ML, Veraitch FS, Mason C, Wall IB, Caldwell MA. Hypoxic culture of human pluripotent stem cell lines is permissible using mouse embryonic fibroblasts. Regenerative Medicine. 7: 675-83. PMID 22954438 DOI: 10.2217/rme.12.55 |
0.301 |
|
2011 |
Hartfield EM, Rinaldi F, Glover CP, Wong LF, Caldwell MA, Uney JB. Connexin 36 expression regulates neuronal differentiation from neural progenitor cells. Plos One. 6: e14746. PMID 21408068 DOI: 10.1371/Journal.Pone.0014746 |
0.432 |
|
2011 |
Cordero-Llana O, Scott SA, Maslen SL, Anderson JM, Boyle J, Chowhdury RR, Tyers P, Barker RA, Kelly CM, Rosser AE, Stephens E, Chandran S, Caldwell MA. Clusterin secreted by astrocytes enhances neuronal differentiation from human neural precursor cells. Cell Death and Differentiation. 18: 907-13. PMID 21212797 DOI: 10.1038/Cdd.2010.169 |
0.793 |
|
2009 |
O'Keeffe GC, Barker RA, Caldwell MA. Dopaminergic modulation of neurogenesis in the subventricular zone of the adult brain. Cell Cycle (Georgetown, Tex.). 8: 2888-94. PMID 19713754 DOI: 10.4161/cc.8.18.9512 |
0.307 |
|
2009 |
Kelly S, Caldwell M, Keasey MP, Cooke JA, Uney JB. Identifying neural progenitor cells in the adult brain. Methods in Molecular Biology (Clifton, N.J.). 549: 217-30. PMID 19378206 DOI: 10.1007/978-1-60327-931-4_15 |
0.386 |
|
2008 |
Hall PE, Lathia JD, Caldwell MA, Ffrench-Constant C. Laminin enhances the growth of human neural stem cells in defined culture media. Bmc Neuroscience. 9: 71. PMID 18651950 DOI: 10.1186/1471-2202-9-71 |
0.337 |
|
2008 |
Barraud P, He X, Caldwell MA, Franklin RJ. Secreted factors from olfactory mucosa cells expanded as free-floating spheres increase neurogenesis in olfactory bulb neurosphere cultures. Bmc Neuroscience. 9: 24. PMID 18282276 DOI: 10.1186/1471-2202-9-24 |
0.304 |
|
2008 |
O'Keeffe FE, Scott SA, Tyers P, O'Keeffe GW, Dalley JW, Zufferey R, Caldwell MA. Induction of A9 dopaminergic neurons from neural stem cells improves motor function in an animal model of Parkinson's disease. Brain : a Journal of Neurology. 131: 630-41. PMID 18202103 DOI: 10.1093/brain/awm340 |
0.457 |
|
2008 |
Ormerod BK, Palmer TD, Caldwell MA. Neurodegeneration and cell replacement. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 363: 153-70. PMID 17331894 DOI: 10.1098/rstb.2006.2018 |
0.334 |
|
2008 |
Chandran S, Caldwell M, Allen N. Introduction: stem cells and brain repair. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 363: 5-7. PMID 17282994 DOI: 10.1098/rstb.2006.2008 |
0.41 |
|
2007 |
Prosser HM, Bradley A, Caldwell MA. Olfactory bulb hypoplasia in Prokr2 null mice stems from defective neuronal progenitor migration and differentiation. The European Journal of Neuroscience. 26: 3339-44. PMID 18052978 DOI: 10.1111/j.1460-9568.2007.05958.x |
0.366 |
|
2007 |
Anderson L, Caldwell MA. Human neural progenitor cell transplants into the subthalamic nucleus lead to functional recovery in a rat model of Parkinson's disease. Neurobiology of Disease. 27: 133-40. PMID 17587588 DOI: 10.1016/j.nbd.2007.03.015 |
0.345 |
|
2007 |
Lim JC, Wolpaw AJ, Caldwell MA, Hladky SB, Barrand MA. Neural precursor cell influences on blood-brain barrier characteristics in rat brain endothelial cells. Brain Research. 1159: 67-76. PMID 17583679 DOI: 10.1016/J.Brainres.2007.05.032 |
0.338 |
|
2007 |
Joannides AJ, Webber DJ, Raineteau O, Kelly C, Irvine KA, Watts C, Rosser AE, Kemp PJ, Blakemore WF, Compston A, Caldwell MA, Allen ND, Chandran S. Environmental signals regulate lineage choice and temporal maturation of neural stem cells from human embryonic stem cells. Brain : a Journal of Neurology. 130: 1263-75. PMID 17472984 DOI: 10.1093/Brain/Awm070 |
0.361 |
|
2007 |
Anderson L, Burnstein RM, He X, Luce R, Furlong R, Foltynie T, Sykacek P, Menon DK, Caldwell MA. Gene expression changes in long term expanded human neural progenitor cells passaged by chopping lead to loss of neurogenic potential in vivo. Experimental Neurology. 204: 512-24. PMID 17306795 DOI: 10.1016/J.Expneurol.2006.12.025 |
0.363 |
|
2006 |
Gaughwin PM, Caldwell MA, Anderson JM, Schwiening CJ, Fawcett JW, Compston DA, Chandran S. Astrocytes promote neurogenesis from oligodendrocyte precursor cells. The European Journal of Neuroscience. 23: 945-56. PMID 16519659 DOI: 10.1111/J.1460-9568.2006.04625.X |
0.552 |
|
2006 |
Joannides A, Fiore-Hériché C, Westmore K, Caldwell M, Compston A, Allen N, Chandran S. Automated mechanical passaging: a novel and efficient method for human embryonic stem cell expansion. Stem Cells (Dayton, Ohio). 24: 230-5. PMID 16510428 DOI: 10.1634/Stemcells.2005-0243 |
0.355 |
|
2005 |
Caldwell MA, He X, Svendsen CN. 5-Bromo-2'-deoxyuridine is selectively toxic to neuronal precursors in vitro. The European Journal of Neuroscience. 22: 2965-70. PMID 16324131 DOI: 10.1111/j.1460-9568.2005.04504.x |
0.547 |
|
2005 |
Watts C, McConkey H, Anderson L, Caldwell M. Anatomical perspectives on adult neural stem cells. Journal of Anatomy. 207: 197-208. PMID 16185244 DOI: 10.1111/J.1469-7580.2005.00448.X |
0.419 |
|
2004 |
Caldwell MA, Garcion E, terBorg MG, He X, Svendsen CN. Heparin stabilizes FGF-2 and modulates striatal precursor cell behavior in response to EGF. Experimental Neurology. 188: 408-20. PMID 15246840 DOI: 10.1016/j.expneurol.2004.05.007 |
0.567 |
|
2004 |
Le Belle JE, Caldwell MA, Svendsen CN. Improving the survival of human CNS precursor-derived neurons after transplantation. Journal of Neuroscience Research. 76: 174-83. PMID 15048915 DOI: 10.1002/jnr.20035 |
0.777 |
|
2004 |
Burnstein RM, Foltynie T, He X, Menon DK, Svendsen CN, Caldwell MA. Differentiation and migration of long term expanded human neural progenitors in a partial lesion model of Parkinson's disease. The International Journal of Biochemistry & Cell Biology. 36: 702-13. PMID 15010333 DOI: 10.1016/J.Biocel.2003.11.011 |
0.583 |
|
2003 |
Wright LS, Li J, Caldwell MA, Wallace K, Johnson JA, Svendsen CN. Gene expression in human neural stem cells: effects of leukemia inhibitory factor. Journal of Neurochemistry. 86: 179-95. PMID 12807438 DOI: 10.1046/j.1471-4159.2003.01826.x |
0.544 |
|
2002 |
Ostenfeld T, Joly E, Tai YT, Peters A, Caldwell M, Jauniaux E, Svendsen CN. Regional specification of rodent and human neurospheres. Brain Research. Developmental Brain Research. 134: 43-55. PMID 11947936 DOI: 10.1016/S0165-3806(01)00291-7 |
0.672 |
|
2002 |
Bahn S, Mimmack M, Ryan M, Caldwell MA, Jauniaux E, Starkey M, Svendsen CN, Emson P. Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study. Lancet. 359: 310-5. PMID 11830198 DOI: 10.1016/S0140-6736(02)07497-4 |
0.585 |
|
2001 |
Caldwell MA, He X, Wilkie N, Pollack S, Marshall G, Wafford KA, Svendsen CN. Growth factors regulate the survival and fate of cells derived from human neurospheres. Nature Biotechnology. 19: 475-9. PMID 11329020 DOI: 10.1038/88158 |
0.656 |
|
2000 |
Svendsen CN, Caldwell MA. Neural stem cells in the developing central nervous system: implications for cell therapy through transplantation. Progress in Brain Research. 127: 13-34. PMID 11142026 DOI: 10.1016/S0079-6123(00)27003-9 |
0.592 |
|
2000 |
Ostenfeld T, Caldwell MA, Prowse KR, Linskens MH, Jauniaux E, Svendsen CN. Human neural precursor cells express low levels of telomerase in vitro and show diminishing cell proliferation with extensive axonal outgrowth following transplantation. Experimental Neurology. 164: 215-26. PMID 10877932 DOI: 10.1006/exnr.2000.7427 |
0.581 |
|
1999 |
Ostenfeld T, Horn P, Aardal C, Orpen I, Caldwell MA, Svendsen CN. Mouse epidermal growth factor-responsive neural precursor cells increase the survival and functional capacity of embryonic rat dopamine neurons in vitro. Neuroreport. 10: 1985-92. PMID 10501545 DOI: 10.1097/00001756-199906230-00035 |
0.627 |
|
1999 |
Svendsen CN, Caldwell MA, Ostenfeld T. Human neural stem cells: isolation, expansion and transplantation. Brain Pathology (Zurich, Switzerland). 9: 499-513. PMID 10416990 DOI: 10.1111/J.1750-3639.1999.Tb00538.X |
0.631 |
|
1998 |
Svendsen CN, ter Borg MG, Armstrong RJ, Rosser AE, Chandran S, Ostenfeld T, Caldwell MA. A new method for the rapid and long term growth of human neural precursor cells. Journal of Neuroscience Methods. 85: 141-52. PMID 9874150 DOI: 10.1016/S0165-0270(98)00126-5 |
0.579 |
|
1998 |
Watts C, Caldwell MA, Dunnett SB. The development of intracerebral cell-suspension implants is influenced by the grafting medium. Cell Transplantation. 7: 573-83. PMID 9853586 DOI: 10.1016/S0963-6897(98)00034-7 |
0.326 |
|
1998 |
Caldwell MA, Svendsen CN. Heparin, but not other proteoglycans potentiates the mitogenic effects of FGF-2 on mesencephalic precursor cells. Experimental Neurology. 152: 1-10. PMID 9682007 DOI: 10.1006/exnr.1998.6815 |
0.556 |
|
1997 |
Svendsen CN, Caldwell MA, Shen J, ter Borg MG, Rosser AE, Tyers P, Karmiol S, Dunnett SB. Long-term survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson's disease. Experimental Neurology. 148: 135-46. PMID 9398456 DOI: 10.1006/Exnr.1997.6634 |
0.622 |
|
1995 |
O'Neill M, Caldwell M, Earley B, Canney M, O'Halloran A, Kelly J, Leonard BE, Junien JL. The sigma receptor ligand JO 1784 (igmesine hydrochloride) is neuroprotective in the gerbil model of global cerebral ischaemia. European Journal of Pharmacology. 283: 217-25. PMID 7498313 DOI: 10.1016/0014-2999(95)00356-P |
0.307 |
|
1994 |
Caldwell M, O'Neill M, Earley B, Leonard B. NG-Nitro-L-arginine protects against ischaemia-induced increases in nitric oxide and hippocampal neuro-degeneration in the gerbil European Journal of Pharmacology. 260: 191-200. PMID 7527344 DOI: 10.1016/0014-2999(94)90337-9 |
0.315 |
|
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