Debra L. Silver, Ph.D. - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Cell migration, Drosophila genetics and cell biology

39/145 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Jowhar Z, Xu A, Venkataramanan S, Dossena F, Hoye ML, Silver DL, Floor SN, Calviello L. A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X. Molecular Systems Biology. PMID 38273160 DOI: 10.1038/s44320-024-00013-0  0.397
2023 Jowhar Z, Xu A, Venkataramanan S, Hoye ML, Silver DL, Floor SN, Calviello L. A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X. Biorxiv : the Preprint Server For Biology. PMID 37214951 DOI: 10.1101/2023.05.11.540322  0.397
2023 Pilaz LJ, Liu J, Joshi K, Tsunekawa Y, Musso CM, D'Arcy BR, Suzuki IK, Alsina FC, Kc P, Sethi S, Vanderhaeghen P, Polleux F, Silver DL. Subcellular mRNA localization and local translation of Arhgap11a in radial glial progenitors regulates cortical development. Neuron. 111: 839-856.e5. PMID 36924763 DOI: 10.1016/j.neuron.2023.02.023  0.381
2022 Hoye ML, Calviello L, Poff AJ, Ejimogu NE, Newman CR, Montgomery MD, Ou J, Floor SN, Silver DL. Aberrant cortical development is driven by impaired cell cycle and translational control in a syndrome model. Elife. 11. PMID 35762573 DOI: 10.7554/eLife.78203  0.301
2020 Hoye ML, Silver DL. Decoding mixed messages in the developing cortex: translational regulation of neural progenitor fate. Current Opinion in Neurobiology. 66: 93-102. PMID 33130411 DOI: 10.1016/j.conb.2020.10.001  0.309
2020 D'Arcy BR, Silver DL. Local gene regulation in radial glia: Lessons from across the nervous system. Traffic (Copenhagen, Denmark). PMID 33058331 DOI: 10.1111/tra.12769  0.373
2020 Mitchell-Dick A, Chalem A, Pilaz LJ, Silver DL. Acute Lengthening of Progenitor Mitosis Influences Progeny Fate during Cortical Development in vivo. Developmental Neuroscience. 1-18. PMID 32541147 DOI: 10.1159/000507113  0.339
2020 Huang Q, Cohen MA, Alsina FC, Devlin G, Garrett A, McKey J, Havlik P, Rakhilin N, Wang E, Xiang K, Mathews P, Wang L, Bock C, Ruthig V, Wang Y, ... ... Silver DL, et al. Intravital imaging of mouse embryos. Science (New York, N.Y.). 368: 181-186. PMID 32273467 DOI: 10.1126/Science.Aba0210  0.338
2020 Lennox AL, Hoye ML, Jiang R, Johnson-Kerner BL, Suit LA, Venkataramanan S, Sheehan CJ, Alsina FC, Fregeau B, Aldinger KA, Moey C, Lobach I, Afenjar A, Babovic-Vuksanovic D, Bézieau S, ... ... Silver DL, et al. Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development. Neuron. PMID 32135084 DOI: 10.1016/J.Neuron.2020.01.042  0.412
2019 Sheehan CJ, McMahon JJ, Serdar LD, Silver DL. Dosage dependent requirements of for cortical interneuron generation and survival. Development (Cambridge, England). PMID 31857347 DOI: 10.1242/Dev.182295  0.365
2018 Vitali I, Fièvre S, Telley L, Oberst P, Bariselli S, Frangeul L, Baumann N, McMahon JJ, Klingler E, Bocchi R, Kiss JZ, Bellone C, Silver DL, Jabaudon D. Progenitor Hyperpolarization Regulates the Sequential Generation of Neuronal Subtypes in the Developing Neocortex. Cell. PMID 30057116 DOI: 10.1016/J.Cell.2018.06.036  0.305
2017 Mitchell C, Silver DL. Enhancing our brains: Genomic mechanisms underlying cortical evolution. Seminars in Cell & Developmental Biology. PMID 28864345 DOI: 10.1016/J.Semcdb.2017.08.045  0.321
2017 Lennox AL, Mao H, Silver DL. RNA on the brain: emerging layers of post-transcriptional regulation in cerebral cortex development. Wiley Interdisciplinary Reviews. Developmental Biology. PMID 28837264 DOI: 10.1002/Wdev.290  0.434
2017 Miller EE, Kobayashi GS, Musso CM, Allen M, Ishiy FA, de Caires Junior LC, Guimarães ES, Griesi-Oliveira K, Zechi-Ceide RM, Richieri-Costa A, Bertola DR, Passos-Bueno MR, Silver DL. EIF4A3 deficient human iPSCs and mouse models demonstrate neural crest defects that underlie Richieri-Costa-Pereira Syndrome. Human Molecular Genetics. PMID 28334780 DOI: 10.1093/Hmg/Ddx078  0.386
2017 Pilaz LJ, Silver DL. Moving messages in the developing brain: Emerging roles for mRNA transport and local translation in neural stem cells. Febs Letters. PMID 28304078 DOI: 10.1002/1873-3468.12626  0.473
2016 Roko Rasin M, Silver D. The crossroads of RNA regulation and function in neurodevelopment. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 55: 101. PMID 27932086 DOI: 10.1016/J.Ijdevneu.2016.11.002  0.397
2016 Pilaz LJ, Lennox AL, Rouanet JP, Silver DL. Dynamic mRNA Transport and Local Translation in Radial Glial Progenitors of the Developing Brain. Current Biology : Cb. PMID 27916527 DOI: 10.1016/J.Cub.2016.10.040  0.463
2016 Mao H, Brown HE, Silver DL. Mouse models of Casc3 reveal developmental functions distinct from other components of the exon junction complex. Rna (New York, N.Y.). PMID 27780844 DOI: 10.1261/Rna.058826.116  0.407
2016 Mao H, McMahon JJ, Tsai YH, Wang Z, Silver DL. Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly. Plos Genetics. 12: e1006282. PMID 27618312 DOI: 10.1371/Journal.Pgen.1006282  0.448
2016 McMahon JJ, Miller EE, Silver DL. The exon junction complex in neural development and neurodevelopmental disease. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. PMID 27071691 DOI: 10.1016/J.Ijdevneu.2016.03.006  0.45
2016 Pilaz LJ, McMahon JJ, Miller EE, Lennox AL, Suzuki A, Salmon E, Silver DL. Prolonged Mitosis of Neural Progenitors Alters Cell Fate in the Developing Brain. Neuron. 89: 83-99. PMID 26748089 DOI: 10.1016/J.Neuron.2015.12.007  0.34
2015 Silver DL. Genomic divergence and brain evolution: How regulatory DNA influences development of the cerebral cortex. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 26642006 DOI: 10.1002/Bies.201500108  0.304
2015 Pilaz LJ, Silver DL. Post-transcriptional regulation in corticogenesis: how RNA-binding proteins help build the brain. Wiley Interdisciplinary Reviews. Rna. 6: 501-15. PMID 26088328 DOI: 10.1002/Wrna.1289  0.456
2015 Mao H, Pilaz LJ, McMahon JJ, Golzio C, Wu D, Shi L, Katsanis N, Silver DL. Rbm8a haploinsufficiency disrupts embryonic cortical development resulting in microcephaly. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 7003-18. PMID 25948253 DOI: 10.1523/Jneurosci.0018-15.2015  0.328
2015 Boyd JL, Skove SL, Rouanet JP, Pilaz LJ, Bepler T, Gordân R, Wray GA, Silver DL. Human-chimpanzee differences in a FZD8 enhancer alter cell-cycle dynamics in the developing neocortex. Current Biology : Cb. 25: 772-9. PMID 25702574 DOI: 10.1016/J.Cub.2015.01.041  0.337
2014 McMahon JJ, Shi L, Silver DL. Generation of a Magoh conditional allele in mice. Genesis (New York, N.Y. : 2000). 52: 752-8. PMID 24771530 DOI: 10.1002/Dvg.22788  0.39
2013 Ruzzo EK, Capo-Chichi JM, Ben-Zeev B, Chitayat D, Mao H, Pappas AL, Hitomi Y, Lu YF, Yao X, Hamdan FF, Pelak K, Reznik-Wolf H, Bar-Joseph I, Oz-Levi D, Lev D, ... ... Silver DL, et al. Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy. Neuron. 80: 429-41. PMID 24139043 DOI: 10.1016/J.Neuron.2013.08.013  0.318
2013 Geisbrecht ER, Sawant K, Su Y, Liu ZC, Silver DL, Burtscher A, Wang X, Zhu AJ, McDonald JA. Genetic interaction screens identify a role for hedgehog signaling in Drosophila border cell migration. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 242: 414-31. PMID 23335293 DOI: 10.1002/Dvdy.23926  0.713
2013 Silver DL, Leeds KE, Hwang HW, Miller EE, Pavan WJ. The EJC component Magoh regulates proliferation and expansion of neural crest-derived melanocytes. Developmental Biology. 375: 172-81. PMID 23333945 DOI: 10.1016/J.Ydbio.2013.01.004  0.409
2010 Silver DL, Watkins-Chow DE, Schreck KC, Pierfelice TJ, Larson DM, Burnetti AJ, Liaw HJ, Myung K, Walsh CA, Gaiano N, Pavan WJ. The exon junction complex component Magoh controls brain size by regulating neural stem cell division. Nature Neuroscience. 13: 551-8. PMID 20364144 DOI: 10.1038/Nn.2527  0.364
2008 Silver DL, Hou L, Somerville R, Young ME, Apte SS, Pavan WJ. The secreted metalloprotease ADAMTS20 is required for melanoblast survival. Plos Genetics. 4: e1000003. PMID 18454205 DOI: 10.1371/Journal.Pgen.1000003  0.384
2008 Matera I, Watkins-Chow DE, Loftus SK, Hou L, Incao A, Silver DL, Rivas C, Elliott EC, Baxter LL, Pavan WJ. A sensitized mutagenesis screen identifies Gli3 as a modifier of Sox10 neurocristopathy. Human Molecular Genetics. 17: 2118-31. PMID 18397875 DOI: 10.1093/Hmg/Ddn110  0.361
2006 Silver DL, Hou L, Pavan WJ. The genetic regulation of pigment cell development. Advances in Experimental Medicine and Biology. 589: 155-69. PMID 17076280 DOI: 10.1007/978-0-387-46954-6_9  0.399
2005 Silver DL, Geisbrecht ER, Montell DJ. Requirement for JAK/STAT signaling throughout border cell migration in Drosophila. Development (Cambridge, England). 132: 3483-92. PMID 16000386 DOI: 10.1242/Dev.01910  0.725
2004 Silver DL, Naora H, Liu J, Cheng W, Montell DJ. Activated signal transducer and activator of transcription (STAT) 3: localization in focal adhesions and function in ovarian cancer cell motility. Cancer Research. 64: 3550-8. PMID 15150111 DOI: 10.1158/0008-5472.Can-03-3959  0.604
2003 Silver DL, Montell DJ. A new trick for Cyclin-Cdk: activation of STAT. Developmental Cell. 4: 148-9. PMID 12586057 DOI: 10.1016/S1534-5807(03)00028-5  0.585
2001 Silver DL, Montell DJ. Paracrine signaling through the JAK/STAT pathway activates invasive behavior of ovarian epithelial cells in Drosophila. Cell. 107: 831-41. PMID 11779460 DOI: 10.1016/S0092-8674(01)00607-9  0.631
1998 Tinker R, Silver D, Montell DJ. Requirement for the vasa RNA helicase in gurken mRNA localization. Developmental Biology. 199: 1-10. PMID 9676188 DOI: 10.1006/Dbio.1998.8941  0.478
1996 Silver DL, Pinaev A, Chen R, De Bruijn FJ. Posttranscriptional Regulation of the Sesbania rostrata Early Nodulin Gene SrEnod2 by Cytokinin. Plant Physiology. 112: 559-567. PMID 12226409  0.343
Low-probability matches (unlikely to be authored by this person)
2009 McCulloch DR, Nelson CM, Dixon LJ, Silver DL, Wylie JD, Lindner V, Sasaki T, Cooley MA, Argraves WS, Apte SS. ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression. Developmental Cell. 17: 687-98. PMID 19922873 DOI: 10.1016/J.Devcel.2009.09.008  0.299
1997 Ford HL, Silver DL, Kachar B, Sellers JR, Zain SB. Effect of Mts1 on the structure and activity of nonmuscle myosin II. Biochemistry. 36: 16321-7. PMID 9405067 DOI: 10.1021/Bi971182L  0.297
2018 Risher WC, Kim N, Koh S, Choi JE, Mitev P, Spence EF, Pilaz LJ, Wang D, Feng G, Silver DL, Soderling SH, Yin HH, Eroglu C. Thrombospondin receptor α2δ-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1. The Journal of Cell Biology. PMID 30054448 DOI: 10.1083/Jcb.201802057  0.295
2014 Pilaz LJ, Silver DL. Live imaging of mitosis in the developing mouse embryonic cortex. Journal of Visualized Experiments : Jove. PMID 24961595 DOI: 10.3791/51298  0.289
1997 Silver DL, Vorotnikov AV, Watterson DM, Shirinsky VP, Sellers JR. Sites of interaction between kinase-related protein and smooth muscle myosin. The Journal of Biological Chemistry. 272: 25353-9. PMID 9312155 DOI: 10.1074/Jbc.272.40.25353  0.269
2023 Lupan BM, Solecki RA, Musso CM, Alsina FC, Silver DL. The exon junction complex component EIF4A3 is essential for mouse and human cortical progenitor mitosis and neurogenesis. Biorxiv : the Preprint Server For Biology. PMID 36711736 DOI: 10.1101/2023.01.13.524010  0.267
2023 Lupan BM, Solecki RA, Musso CM, Alsina FC, Silver DL. The exon junction complex component EIF4A3 is essential for mouse and human cortical progenitor mitosis and neurogenesis. Development (Cambridge, England). PMID 37139782 DOI: 10.1242/dev.201619  0.267
2018 McFadden MJ, Mitchell-Dick A, Vazquez C, Roder AE, Labagnara KF, McMahon JJ, Silver DL, Horner SM. A Fluorescent Cell-Based System for Imaging Zika Virus Infection in Real-Time. Viruses. 10. PMID 29495257 DOI: 10.3390/V10020095  0.264
2016 Singh SK, Stogsdill JA, Pulimood NS, Dingsdale H, Kim YH, Pilaz LJ, Kim IH, Manhaes AC, Rodrigues WS, Pamukcu A, Enustun E, Ertuz Z, Scheiffele P, Soderling SH, Silver DL, et al. Astrocytes Assemble Thalamocortical Synapses by Bridging NRX1α and NL1 via Hevin. Cell. 164: 183-196. PMID 26771491 DOI: 10.1016/J.Cell.2015.11.034  0.263
2020 Fishell G, Silver DL. Decision letter: Clustered gamma-protocadherins regulate cortical interneuron programmed cell death Elife. DOI: 10.7554/Elife.55374.Sa1  0.26
2023 D'Arcy BR, Lennox AL, Manso Musso C, Bracher A, Escobar-Tomlienovich C, Perez-Sanchez S, Silver DL. Non-muscle myosins control radial glial basal endfeet to mediate interneuron organization. Plos Biology. 21: e3001926. PMID 36854011 DOI: 10.1371/journal.pbio.3001926  0.253
2014 Risher WC, Patel S, Kim IH, Uezu A, Bhagat S, Wilton DK, Pilaz LJ, Singh Alvarado J, Calhan OY, Silver DL, Stevens B, Calakos N, Soderling SH, Eroglu C. Astrocytes refine cortical connectivity at dendritic spines. Elife. 3. PMID 25517933 DOI: 10.7554/Elife.04047  0.252
2019 Alsina FC, Silver DL. Damage Control in the Developing Brain: Tradeoffs and Consequences. Trends in Neurosciences. PMID 31447171 DOI: 10.1016/J.Tins.2019.08.004  0.228
2019 Silver D. A window into cortical development through the lens of RNA dynamics Ibro Reports. 6: S7-S8. DOI: 10.1016/j.ibror.2019.07.007  0.221
2012 Moir RD, Gross DA, Silver DL, Willis IM. SCS3 and YFT2 link transcription of phospholipid biosynthetic genes to ER stress and the UPR. Plos Genetics. 8: e1002890. PMID 22927826 DOI: 10.1371/Journal.Pgen.1002890  0.219
1998 Chen R, Silver DL, de Bruijn FJ. Nodule parenchyma-specific expression of the sesbania rostrata early nodulin gene SrEnod2 is mediated by its 3' untranslated region The Plant Cell. 10: 1585-602. PMID 9761788 DOI: 10.1105/tpc.10.10.1585  0.202
2010 Gross DA, Snapp EL, Silver DL. Structural insights into triglyceride storage mediated by fat storage-inducing transmembrane (FIT) protein 2. Plos One. 5: e10796. PMID 20520733 DOI: 10.1371/Journal.Pone.0010796  0.198
2014 Risher WC, Patel S, Kim IH, Uezu A, Bhagat S, Wilton DK, Pilaz L, Alvarado JS, Calhan OY, Silver DL, Stevens B, Calakos N, Soderling SH, Eroglu C. Author response: Astrocytes refine cortical connectivity at dendritic spines Elife. DOI: 10.7554/Elife.04047.022  0.191
2011 Gross DA, Zhan C, Silver DL. Direct binding of triglyceride to fat storage-inducing transmembrane proteins 1 and 2 is important for lipid droplet formation. Proceedings of the National Academy of Sciences of the United States of America. 108: 19581-6. PMID 22106267 DOI: 10.1073/Pnas.1110817108  0.19
2011 Shimizu T, Sugiura T, Wakayama T, Kijima A, Nakamichi N, Iseki S, Silver DL, Kato Y. PDZK1 regulates breast cancer resistance protein in small intestine. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 2148-54. PMID 21816982 DOI: 10.1124/dmd.111.040295  0.19
2008 Zhu W, Saddar S, Seetharam D, Chambliss KL, Longoria C, Silver DL, Yuhanna IS, Shaul PW, Mineo C. The scavenger receptor class B type I adaptor protein PDZK1 maintains endothelial monolayer integrity. Circulation Research. 102: 480-7. PMID 18174467 DOI: 10.1161/CIRCRESAHA.107.159079  0.189
2021 Liu J, Mosti F, Silver DL. Human brain evolution: Emerging roles for regulatory DNA and RNA. Current Opinion in Neurobiology. 71: 170-177. PMID 34861533 DOI: 10.1016/j.conb.2021.11.005  0.187
2002 Silver DL. A carboxyl-terminal PDZ-interacting domain of scavenger receptor B, type I is essential for cell surface expression in liver. The Journal of Biological Chemistry. 277: 34042-7. PMID 12119305 DOI: 10.1074/jbc.M206584200  0.181
2003 Wang N, Chen W, Linsel-Nitschke P, Martinez LO, Agerholm-Larsen B, Silver DL, Tall AR. A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I. The Journal of Clinical Investigation. 111: 99-107. PMID 12511593 DOI: 10.1172/JCI16808  0.18
2012 Berger JH, Charron MJ, Silver DL. Major facilitator superfamily domain-containing protein 2a (MFSD2A) has roles in body growth, motor function, and lipid metabolism. Plos One. 7: e50629. PMID 23209793 DOI: 10.1371/journal.pone.0050629  0.179
2012 Nguyen LN, Cesar GV, Le GT, Silver DL, Nimrichter L, Nosanchuk JD. Inhibition of Candida parapsilosis fatty acid synthase (Fas2) induces mitochondrial cell death in serum. Plos Pathogens. 8: e1002879. PMID 22952445 DOI: 10.1371/journal.ppat.1002879  0.171
2011 Nguyen LN, Hamari Z, Kadereit B, Trofa D, Agovino M, Martinez LR, Gacser A, Silver DL, Nosanchuk JD. Candida parapsilosis fat storage-inducing transmembrane (FIT) protein 2 regulates lipid droplet formation and impacts virulence. Microbes and Infection / Institut Pasteur. 13: 663-72. PMID 21396481 DOI: 10.1016/J.Micinf.2011.02.009  0.17
2005 Wang P, Wang JJ, Xiao Y, Murray JW, Novikoff PM, Angeletti RH, Orr GA, Lan D, Silver DL, Wolkoff AW. Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface. The Journal of Biological Chemistry. 280: 30143-9. PMID 15994332 DOI: 10.1074/Jbc.M503969200  0.166
2013 Gross DA, Silver DL. Purification of integral membrane proteins and lipid-binding assays. Methods in Cell Biology. 116: 191-211. PMID 24099294 DOI: 10.1016/B978-0-12-408051-5.00010-3  0.161
2014 Siddiqi S, Foo JN, Vu A, Azim S, Silver DL, Mansoor A, Tay SK, Abbasi S, Hashmi AH, Janjua J, Khalid S, Tai ES, Yeo GW, Khor CC. A novel splice-site mutation in ALS2 establishes the diagnosis of juvenile amyotrophic lateral sclerosis in a family with early onset anarthria and generalized dystonias. Plos One. 9: e113258. PMID 25474699 DOI: 10.1371/Journal.Pone.0113258  0.159
2015 Alakbarzade V, Hameed A, Quek DQ, Chioza BA, Baple EL, Cazenave-Gassiot A, Nguyen LN, Wenk MR, Ahmad AQ, Sreekantan-Nair A, Weedon MN, Rich P, Patton MA, Warner TT, Silver DL, et al. A partially inactivating mutation in the sodium-dependent lysophosphatidylcholine transporter MFSD2A causes a non-lethal microcephaly syndrome. Nature Genetics. 47: 814-7. PMID 26005865 DOI: 10.1038/ng.3313  0.157
2008 Sugiura T, Kato Y, Wakayama T, Silver DL, Kubo Y, Iseki S, Tsuji A. PDZK1 regulates two intestinal solute carriers (Slc15a1 and Slc22a5) in mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 1181-8. PMID 18322073 DOI: 10.1124/dmd.107.020321  0.156
2003 Silver DL, Wang N, Vogel S. Identification of small PDZK1-associated protein, DD96/MAP17, as a regulator of PDZK1 and plasma high density lipoprotein levels. The Journal of Biological Chemistry. 278: 28528-32. PMID 12754212 DOI: 10.1074/jbc.M304109200  0.153
2015 Goh VJ, Tan JS, Tan BC, Seow C, Ong WY, Lim YC, Sun L, Ghosh S, Silver DL. Postnatal deletion of Fat storage-inducing Transmembrane Protein 2 (FIT2/FITM2) causes lethal enteropathy. The Journal of Biological Chemistry. PMID 26304121 DOI: 10.1074/jbc.M115.676700  0.151
2014 Tan JS, Seow CJ, Goh VJ, Silver DL. Recent advances in understanding proteins involved in lipid droplet formation, growth and fusion. Journal of Genetics and Genomics = Yi Chuan Xue Bao. 41: 251-9. PMID 24894352 DOI: 10.1016/j.jgg.2014.03.003  0.144
2000 Silver DL, Wang N, Tall AR. Defective HDL particle uptake in ob/ob hepatocytes causes decreased recycling, degradation, and selective lipid uptake. The Journal of Clinical Investigation. 105: 151-9. PMID 10642593 DOI: 10.1172/JCI8087  0.141
2015 Guemez-Gamboa A, Nguyen LN, Yang H, Zaki MS, Kara M, Ben-Omran T, Akizu N, Rosti RO, Rosti B, Scott E, Schroth J, Copeland B, Vaux KK, Cazenave-Gassiot A, Quek DQ, ... ... Silver DL, et al. Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome. Nature Genetics. 47: 809-13. PMID 26005868 DOI: 10.1038/Ng.3311  0.14
1999 Silver DL, Jiang XC, Tall AR. Increased high density lipoprotein (HDL), defective hepatic catabolism of ApoA-I and ApoA-II, and decreased ApoA-I mRNA in ob/ob mice. Possible role of leptin in stimulation of HDL turnover. The Journal of Biological Chemistry. 274: 4140-6. PMID 9933608 DOI: 10.1074/jbc.274.7.4140  0.14
2005 Assanasen C, Mineo C, Seetharam D, Yuhanna IS, Marcel YL, Connelly MA, Williams DL, de la Llera-Moya M, Shaul PW, Silver DL. Cholesterol binding, efflux, and a PDZ-interacting domain of scavenger receptor-BI mediate HDL-initiated signaling. The Journal of Clinical Investigation. 115: 969-77. PMID 15841181 DOI: 10.1172/Jci200523858  0.14
2005 Lan D, Silver DL. Fenofibrate induces a novel degradation pathway for scavenger receptor B-I independent of PDZK1. The Journal of Biological Chemistry. 280: 23390-6. PMID 15837786 DOI: 10.1074/jbc.M502777200  0.139
2015 Lu GD, Ang YH, Zhou J, Tamilarasi J, Yan B, Lim YC, Srivastava S, Salto-Tellez M, Hui KM, Shen HM, Nguyen LN, Tan BC, Silver DL, Hooi SC. CCAAT/enhancer binding protein α predicts poorer prognosis and prevents energy starvation-induced cell death in hepatocellular carcinoma. Hepatology (Baltimore, Md.). 61: 965-78. PMID 25363290 DOI: 10.1002/hep.27593  0.138
2010 Sugiura T, Otake T, Shimizu T, Wakayama T, Silver DL, Utsumi R, Nishimura T, Iseki S, Nakamichi N, Kubo Y, Tsuji A, Kato Y. PDZK1 regulates organic anion transporting polypeptide Oatp1a in mouse small intestine. Drug Metabolism and Pharmacokinetics. 25: 588-98. PMID 21084765 DOI: JST.JSTAGE/dmpk/DMPK-10-RG-074  0.138
2022 Mangan RJ, Alsina FC, Mosti F, Sotelo-Fonseca JE, Snellings DA, Au EH, Carvalho J, Sathyan L, Johnson GD, Reddy TE, Silver DL, Lowe CB. Adaptive sequence divergence forged new neurodevelopmental enhancers in humans. Cell. 185: 4587-4603.e23. PMID 36423581 DOI: 10.1016/j.cell.2022.10.016  0.136
2014 Miranda DA, Kim JH, Nguyen LN, Cheng W, Tan BC, Goh VJ, Tan JS, Yaligar J, Kn BP, Velan SS, Wang H, Silver DL. Fat storage-inducing transmembrane protein 2 is required for normal fat storage in adipose tissue. The Journal of Biological Chemistry. 289: 9560-72. PMID 24519944 DOI: 10.1074/Jbc.M114.547687  0.134
2003 Sun Y, Hao M, Luo Y, Liang CP, Silver DL, Cheng C, Maxfield FR, Tall AR. Stearoyl-CoA desaturase inhibits ATP-binding cassette transporter A1-mediated cholesterol efflux and modulates membrane domain structure. The Journal of Biological Chemistry. 278: 5813-20. PMID 12482877 DOI: 10.1074/Jbc.M208687200  0.128
2000 Wang N, Silver DL, Costet P, Tall AR. Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1. The Journal of Biological Chemistry. 275: 33053-8. PMID 10918065 DOI: 10.1074/jbc.M005438200  0.127
2005 Ganesan S, Richardson AL, Wang ZC, Iglehart JD, Miron A, Feunteun J, Silver D, Livingston DM. Abnormalities of the inactive X chromosome are a common feature of BRCA1 mutant and sporadic basal-like breast cancer. Cold Spring Harbor Symposia On Quantitative Biology. 70: 93-7. PMID 16869742 DOI: 10.1101/Sqb.2005.70.045  0.127
2008 Kadereit B, Kumar P, Wang WJ, Miranda D, Snapp EL, Severina N, Torregroza I, Evans T, Silver DL. Evolutionarily conserved gene family important for fat storage. Proceedings of the National Academy of Sciences of the United States of America. 105: 94-9. PMID 18160536 DOI: 10.1073/Pnas.0708579105  0.123
2014 Siddiqi S, Foo JN, Vu A, Azim S, Silver DL, Mansoor A, Tay SKH, Abbasi S, Hashmi AH, Janjua J, Khalid S, Tai ES, Yeo GW, Khor CC. A novel splice-site mutation in ALS establishes the diagnosis of juvenile amyotrophic lateral sclerosis in a family with early onset anarthria and generalized dystonias Plos One. 9. DOI: 10.1371/journal.pone.011325  0.123
2001 Nakae J, Kitamura T, Silver DL, Accili D. The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. The Journal of Clinical Investigation. 108: 1359-67. PMID 11696581 DOI: 10.1172/Jci12876  0.119
2000 Silver DL, Jiang XC, Arai T, Bruce C, Tall AR. Receptors and lipid transfer proteins in HDL metabolism. Annals of the New York Academy of Sciences. 902: 103-11; discussion 1. PMID 10865830  0.118
2000 Chen W, Silver DL, Smith JD, Tall AR. Scavenger receptor-BI inhibits ATP-binding cassette transporter 1- mediated cholesterol efflux in macrophages. The Journal of Biological Chemistry. 275: 30794-800. PMID 10896940 DOI: 10.1074/jbc.M004552200  0.114
2001 Silver DL, Wang N, Xiao X, Tall AR. High density lipoprotein (HDL) particle uptake mediated by scavenger receptor class B type 1 results in selective sorting of HDL cholesterol from protein and polarized cholesterol secretion. The Journal of Biological Chemistry. 276: 25287-93. PMID 11301333 DOI: 10.1074/jbc.M101726200  0.113
2021 Liu J, Silver DL. Founder cells shape brain evolution. Cell. 184: 1965-1967. PMID 33861961 DOI: 10.1016/j.cell.2021.03.045  0.112
2011 Nagajyothi F, Weiss LM, Silver DL, Desruisseaux MS, Scherer PE, Herz J, Tanowitz HB. Trypanosoma cruzi utilizes the host low density lipoprotein receptor in invasion. Plos Neglected Tropical Diseases. 5: e953. PMID 21408103 DOI: 10.1371/Journal.Pntd.0000953  0.11
2001 Wang N, Silver DL, Thiele C, Tall AR. ATP-binding cassette transporter A1 (ABCA1) functions as a cholesterol efflux regulatory protein. The Journal of Biological Chemistry. 276: 23742-7. PMID 11309399 DOI: 10.1074/jbc.M102348200  0.109
2020 Lupan BM, Silver DL. Evolution: Does More Time Buy More Neurons? Current Biology : Cb. 30: R1316-R1318. PMID 33142101 DOI: 10.1016/j.cub.2020.08.098  0.105
2021 Mosti F, Silver DL. Uncovering the HARbingers of human brain evolution. Neuron. 109: 3231-3233. PMID 34672980 DOI: 10.1016/j.neuron.2021.09.022  0.105
2008 Hussain S, Peters R, Silver DL. Using received signal strength variation for surveillance in residential areas Proceedings of Spie - the International Society For Optical Engineering. 6973. DOI: 10.1117/12.778008  0.103
2006 Zhou H, Li Z, Silver DL, Jiang XC. Cholesteryl ester transfer protein (CETP) expression enhances HDL cholesteryl ester liver delivery, which is independent of scavenger receptor BI, LDL receptor related protein and possibly LDL receptor. Biochimica Et Biophysica Acta. 1761: 1482-8. PMID 17055779 DOI: 10.1016/j.bbalip.2006.09.008  0.1
2013 Goh VJ, Silver DL. The lipid droplet as a potential therapeutic target in NAFLD. Seminars in Liver Disease. 33: 312-20. PMID 24222089 DOI: 10.1055/s-0033-1358521  0.099
2014 Kim HJ, Cho H, Alexander R, Patterson HC, Gu M, Lo KA, Xu D, Goh VJ, Nguyen LN, Chai X, Huang CX, Kovalik JP, Ghosh S, Trajkovski M, Silver DL, et al. MicroRNAs are required for the feature maintenance and differentiation of brown adipocytes. Diabetes. 63: 4045-56. PMID 25008181 DOI: 10.2337/Db14-0466  0.098
2014 Nguyen LN, Ma D, Shui G, Wong P, Cazenave-Gassiot A, Zhang X, Wenk MR, Goh EL, Silver DL. Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid. Nature. 509: 503-6. PMID 24828044 DOI: 10.1038/nature13241  0.096
2001 Silver DL, Tall AR. The cellular biology of scavenger receptor class B type I. Current Opinion in Lipidology. 12: 497-504. PMID 11561168 DOI: 10.1097/00041433-200110000-00004  0.089
2014 Gross DA, Silver DL. Cytosolic lipid droplets: from mechanisms of fat storage to disease. Critical Reviews in Biochemistry and Molecular Biology. 49: 304-26. PMID 25039762 DOI: 10.3109/10409238.2014.931337  0.079
2011 Miranda DA, Koves TR, Gross DA, Chadt A, Al-Hasani H, Cline GW, Schwartz GJ, Muoio DM, Silver DL. Re-patterning of skeletal muscle energy metabolism by fat storage-inducing transmembrane protein 2. The Journal of Biological Chemistry. 286: 42188-99. PMID 22002063 DOI: 10.1074/Jbc.M111.297127  0.078
2006 Silver DL, Pavan WJ. The origin and development of neural crest-derived melanocytes From Melanocytes to Melanoma: the Progression to Malignancy. 3-26. DOI: 10.1007/978-1-59259-994-3_1  0.078
2004 Silver DL. SR-BI and protein-protein interactions in hepatic high density lipoprotein metabolism. Reviews in Endocrine & Metabolic Disorders. 5: 327-33. PMID 15486465 DOI: 10.1023/B:REMD.0000045104.38104.8e  0.071
2021 Baldwin KT, Silver DL. Expanding gliogenesis. Science (New York, N.Y.). 372: 1151-1152. PMID 34112682 DOI: 10.1126/science.abj1139  0.064
2023 Sozen B, Flavell RA, Lamming DW, Silver DL, Parrinello S, Abate-Shen C, Michor F, Sankaran VG. What approaches are needed to understand human development and disease? Developmental Cell. 58: 2822-2825. PMID 38113848 DOI: 10.1016/j.devcel.2023.11.026  0.058
2011 Takeuchi K, Sugiura T, Umeda S, Matsubara K, Horikawa M, Nakamichi N, Silver DL, Ishiwata N, Kato Y. Pharmacokinetics and hepatic uptake of eltrombopag, a novel platelet-increasing agent. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1088-96. PMID 21422191 DOI: 10.1124/dmd.110.037960  0.049
1996 Hurwitz GA, Weingert ME, Silver DL, MacDonald AC, Finnie KJ, Powe JE, Dawdy JA. The usefulness of stress tests performed in the nuclear medicine department: mathematical methods to assess efficacy at various angiographic endpoints. Nuclear Medicine Communications. 17: 463-74. PMID 8822743  0.046
2005 Roy S, Hyogo H, Yadav SK, Wu MK, Jelicks LA, Locker JD, Frank PG, Lisanti MP, Silver DL, Cohen DE. A biphasic response of hepatobiliary cholesterol metabolism to dietary fat at the onset of obesity in the mouse. Hepatology (Baltimore, Md.). 41: 887-95. PMID 15793852 DOI: 10.1002/Hep.20643  0.042
2008 Silver DL, Poirier R, Currie D. Inductive transfer with context-sensitive neural networks Machine Learning. 73: 313-336. DOI: 10.1007/s10994-008-5088-0  0.036
1997 Silver DL, Hurwitz GA. The predictive and explanatory power of inductive decision trees: a comparison with artificial neural network learning as applied to the noninvasive diagnosis of coronary artery disease. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 45: 99-108. PMID 9084580  0.033
2005 Blustein J, Silver DL, Fu CL. Information visualization for an intrusion detection system Pst 2005 - 3rd Annual Conference On Privacy, Security and Trust, Conference Proceedings. DOI: 10.1145/1083356.1083419  0.029
2007 Silver DL, Poirier R. Requirements for machine lifelong learning Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4527: 313-319.  0.028
2015 Silver DL, Mason G, Eljabu L. Consolidation using sweep task rehearsal: Overcoming the stability-plasticity problem Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 9091: 307-322. DOI: 10.1007/978-3-319-18356-5_27  0.027
2010 Tu L, Fowler B, Silver DL. CsMTL MLP for WEKA: Neural network learning with inductive transfer Proceedings of the 23rd International Florida Artificial Intelligence Research Society Conference, Flairs-23. 128-133.  0.024
2013 Wang T, Iqbal MS, Silver DL. An unsupervised deep-learning architecture that can reconstruct paired images Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 8170: 388-396. DOI: 10.1007/978-3-642-41218-9_42  0.024
2005 Poirier R, Silver DL. Effect of curriculum on the consolidation of neural network task knowledge Proceedings of the International Joint Conference On Neural Networks. 4: 2123-2128. DOI: 10.1109/IJCNN.2005.1556228  0.021
2012 Guyon I, Dror G, Lemaire V, Silver DL, Taylor G, Aha DW. Analysis of the IJCNN 2011 UTL challenge. Neural Networks : the Official Journal of the International Neural Network Society. 32: 174-8. PMID 22374109 DOI: 10.1016/J.Neunet.2012.02.010  0.02
2007 Silver DL, Poirier R. Context-sensitive MTL networks for machine lifelong learning Proceedings of the Twentieth International Florida Artificial Intelligence Research Society Conference, Flairs 2007. 628-633.  0.019
1996 Schweitzer MA, Sweiss I, Silver DL, Stellato TA. The clinical spectrum of Clostridium difficile colitis in immunocompromised patients. The American Surgeon. 62: 603-7; discussion 60. PMID 8651560  0.017
2008 Silver DL, Bennett KP. Guest editor's introduction: Special issue on inductive transfer learning Machine Learning. 73: 215-220. DOI: 10.1007/s10994-008-5087-1  0.017
2010 Ma Z, Silver DL, Shakshuki EM. User profile management: Reference model and web services implementation International Journal of Web and Grid Services. 6: 1-34. DOI: 10.1504/Ijwgs.2010.032189  0.015
2011 Fowler B, Silver DL. Consolidation using context-sensitive multiple task learning Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6657: 128-139. DOI: 10.1007/978-3-642-21043-3-16  0.014
2011 Silver DL. Machine lifelong learning: Challenges and benefits for artificial general intelligence Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 6830: 370-375. DOI: 10.1007/978-3-642-22887-2_45  0.014
2007 Silver DL, Mercer RE. Sequential inductive transfer for coronary artery disease diagnosis Ieee International Conference On Neural Networks - Conference Proceedings. 2635-2641. DOI: 10.1109/IJCNN.2007.4371374  0.013
2015 Wang T, Silver DL. Learning paired-associate images with an unsupervised deep learning architecture Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 9091: 250-263. DOI: 10.1007/978-3-319-18356-5_22  0.013
2007 Silver DL, Gaudette L, Spooner I. Inductive transfer applied to stream discharge modeling Conference Proceedings - Ieee International Conference On Systems, Man and Cybernetics. 528-534. DOI: 10.1109/ICSMC.2007.4414103  0.013
2013 Silver DL. The consolidation of task knowledge for lifelong machine learning Aaai Spring Symposium - Technical Report. 46-48.  0.012
2015 Gomes JE, Silver DL. Learning to reason in a Probably Approximately Correct manner Canadian Conference On Electrical and Computer Engineering. 2015: 1475-1478. DOI: 10.1109/CCECE.2015.7129498  0.012
2014 Silver DL, Poirier R. Sequential consolidation of learned task knowledge Lecture Notes in Artificial Intelligence (Subseries of Lecture Notes in Computer Science). 3060: 217-232.  0.01
2013 Silver DL, Yang Q, Li L. Lifelong machine learning systems: Beyond learning algorithms Aaai Spring Symposium - Technical Report. 49-55.  0.01
2012 Silver DL, Tu L. Image morphing: Transfer learning between tasks that have multiple outputs Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 7310: 194-205. DOI: 10.1007/978-3-642-30353-1_17  0.01
2009 Silver DL. Hepatic Fatty Acid Metabolism and Dysfunction The Liver: Biology and Pathobiology: Fifth Edition. 257-270. DOI: 10.1002/9780470747919.ch18  0.01
2008 Silver DL, Tu L. Image transformation: Inductive transfer between multiple tasks having multiple outputs Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5032: 296-307. DOI: 10.1007/978-3-540-68825-9_28  0.01
2007 Xiaoyan P, Silver DL. Interface adaptation based on user expectation Proceedings - 21st International Conference On Advanced Information Networking and Applications Workshops/Symposia, Ainaw'07. 1: 264-269. DOI: 10.1109/AINAW.2007.211  0.01
2006 Silver DL, Biggs AJ. Keystroke and eye-tracking biometrics for user identification Proceedings of the 2006 International Conference On Artificial Intelligence, Icai'06. 2: 344-348.  0.01
2005 Peng X, Silver DL. User control over user adaptation: A case study Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 3538: 443-447. DOI: 10.1016/j.matchemphys.2005.01.045  0.01
2005 Silver DL, Alisch R. A measure of relatedness for selecting consolidated task knowledge Proceedings of the Eighteenth International Florida Artificial Intelligence Research Society Conference, Flairs 2005 - Recent Advances in Artifical Intelligence. 399-404.  0.01
2003 Silver DL, McCracken P. Selective transfer of task knowledge using stochastic noise Lecture Notes in Artificial Intelligence (Subseries of Lecture Notes in Computer Science). 2671: 190-205. DOI: 10.1007/3-540-44886-1_16  0.01
1996 Silver DL, Mercer RE. The Parallel Transfer of Task Knowledge Using Dynamic Learning Rates Based on a Measure of Relatedness Connection Science. 8: 277-294. DOI: 10.1080/095400996116929  0.01
1972 Tseng HC, Silver DL, Finlayson BA. Application of the continuum theory to nematic liquid crystals Physics of Fluids. 15: 1213-1222.  0.01
1969 Silver DL. A look at evaluation of VR counselor performance. Journal of Rehabilitation. 35: 13-4. PMID 4242554  0.01
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