| Year |
Citation |
Score |
| 2023 |
Hill SE, Beaulieu-Abdelahad D, Lemus A, Webster JM, Ospina SR, Darling AL, Martin MD, Patel S, Bridenstine L, Swonger R, Paul S, Blackburn R, Calcul L, Dickey CA, Leahy JW, et al. . Acs Chemical Biology. PMID 37144894 DOI: 10.1021/acschembio.2c00919 |
0.84 |
|
| 2022 |
Hill SE, Esquivel AR, Ospina SR, Rahal LM, Dickey CA, Blair LJ. Chaperoning activity of the cyclophilin family prevents tau aggregation. Protein Science : a Publication of the Protein Society. 31: e4448. PMID 36305768 DOI: 10.1002/pro.4448 |
0.834 |
|
| 2022 |
Rodriguez Ospina S, Blazier DM, Criado-Marrero M, Gould LA, Gebru NT, Beaulieu-Abdelahad D, Wang X, Remily-Wood E, Chaput D, Stevens S, Uversky VN, Bickford PC, Dickey CA, Blair LJ. Small Heat Shock Protein 22 Improves Cognition and Learning in the Tauopathic Brain. International Journal of Molecular Sciences. 23. PMID 35055033 DOI: 10.3390/ijms23020851 |
0.843 |
|
| 2021 |
Criado-Marrero M, Gebru NT, Gould LA, Blazier DM, Vidal-Aguiar Y, Smith TM, Abdelmaboud SS, Shelton LB, Wang X, Dahrendorff J, Beaulieu-Abdelahad D, Dickey CA, Blair LJ. FKBP52 overexpression accelerates hippocampal-dependent memory impairments in a tau transgenic mouse model. Npj Aging and Mechanisms of Disease. 7: 9. PMID 33941782 DOI: 10.1038/s41514-021-00062-x |
0.823 |
|
| 2021 |
Darling AL, Dahrendorff J, Creodore SG, Dickey CA, Blair LJ, Uversky VN. Small heat shock protein 22kDa can modulate the aggregation and liquid-liquid phase separation behavior of Tau. Protein Science : a Publication of the Protein Society. PMID 33686711 DOI: 10.1002/pro.4060 |
0.825 |
|
| 2021 |
Sandusky-Beltran LA, Kovalenko A, Placides DS, Ratnasamy K, Ma C, Hunt JB, Liang H, Calahatian JIT, Michalski C, Fahnestock M, Blair LJ, Darling AL, Baker JD, Fontaine SN, Dickey CA, et al. Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology. The Journal of Clinical Investigation. 131. PMID 33586680 DOI: 10.1172/JCI126299 |
0.82 |
|
| 2020 |
Criado-Marrero M, Smith TM, Gould LA, Kim S, Penny HJ, Sun Z, Gulick D, Dickey CA, Blair LJ. FKBP5 and early life stress affect the hippocampus by an age-dependent mechanism. Brain, Behavior, & Immunity - Health. 9: 100143. PMID 34589890 DOI: 10.1016/j.bbih.2020.100143 |
0.757 |
|
| 2020 |
Webster JM, Darling AL, Sanders TA, Blazier DM, Vidal-Aguiar Y, Beaulieu-Abdelahad D, Plemmons DG, Hill SE, Uversky VN, Bickford PC, Dickey CA, Blair LJ. Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels. International Journal of Molecular Sciences. 21. PMID 32751642 DOI: 10.3390/Ijms21155442 |
0.843 |
|
| 2020 |
Singh JK, Hutt DM, Tait B, Guy NC, Sivils JC, Ortiz NR, Payan AN, Komaragiri SK, Owens JJ, Culbertson D, Blair LJ, Dickey C, Kuo SY, Finley D, Dyson HJ, et al. Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone. Cell Chemical Biology. PMID 32017918 DOI: 10.1016/J.Chembiol.2020.01.008 |
0.806 |
|
| 2020 |
Criado-Marrero M, Sabbagh JJ, Jones MR, Chaput D, Dickey CA, Blair ALJ. Hippocampal Neurogenesis Is Enhanced in Adult Tau Deficient Mice. Cells. 9. PMID 31947657 DOI: 10.3390/cells9010210 |
0.51 |
|
| 2019 |
Hill SE, Kwon MS, Martin MD, Suntharalingam A, Hazel A, Dickey CA, Gumbart JC, Lieberman RL. Stable calcium-free myocilin olfactomedin domain variants reveal challenges in differentiating between benign and glaucoma-causing mutations. The Journal of Biological Chemistry. PMID 31270212 DOI: 10.1074/Jbc.Ra119.009419 |
0.407 |
|
| 2019 |
Sandusky-Beltran LA, Kovalenko A, Ma C, Calahatian JIT, Placides DS, Watler MD, Hunt JB, Darling AL, Baker JD, Blair LJ, Martin MD, Fontaine SN, Dickey CA, Lussier AL, Weeber EJ, et al. Spermidine/spermine-N-acetyltransferase ablation impacts tauopathy-induced polyamine stress response. Alzheimer's Research & Therapy. 11: 58. PMID 31253191 DOI: 10.1186/S13195-019-0507-Y |
0.812 |
|
| 2019 |
Criado-Marrero M, Gebru NT, Gould LA, Smith TM, Kim S, Blackburn RJ, Dickey CA, Blair LJ. Early Life Stress and High FKBP5 Interact to Increase Anxiety-Like Symptoms through Altered AKT Signaling in the Dorsal Hippocampus. International Journal of Molecular Sciences. 20. PMID 31167373 DOI: 10.3390/ijms20112738 |
0.778 |
|
| 2019 |
Blair LJ, Criado-Marrero M, Zheng D, Wang X, Kamath S, Nordhues BA, Weeber EJ, Dickey CA. The Disease-Associated Chaperone FKBP51 Impairs Cognitive Function by Accelerating AMPA Receptor Recycling. Eneuro. 6. PMID 30963102 DOI: 10.1523/ENEURO.0242-18.2019 |
0.765 |
|
| 2019 |
Darling AL, Breydo L, Rivas EG, Gebru NT, Zheng D, Baker JD, Blair LJ, Dickey CA, Koren J, Uversky VN. Repeated repeat problems: Combinatorial effect of C9orf72-derived dipeptide repeat proteins. International Journal of Biological Macromolecules. PMID 30639592 DOI: 10.1016/J.Ijbiomac.2019.01.035 |
0.787 |
|
| 2018 |
Oroz J, Chang BJ, Wysoczanski P, Lee CT, Pérez-Lara Á, Chakraborty P, Hofele RV, Baker JD, Blair LJ, Biernat J, Urlaub H, Mandelkow E, Dickey CA, Zweckstetter M. Structure and pro-toxic mechanism of the human Hsp90/PPIase/Tau complex. Nature Communications. 9: 4532. PMID 30382094 DOI: 10.1038/s41467-018-06880-0 |
0.814 |
|
| 2018 |
Sabbagh JJ, Cordova RA, Zheng D, Criado-Marrero M, Lemus A, Li P, Baker JD, Nordhues BA, Darling AL, Martinez-Licha C, Rutz DA, Patel S, Buchner J, Leahy JW, Koren J, ... Dickey CA, et al. Targeting the FKBP51/GR/Hsp90 complex to identify functionally relevant treatments for depression and PTSD. Acs Chemical Biology. PMID 29893552 DOI: 10.1021/Acschembio.8B00454 |
0.804 |
|
| 2018 |
Mok SA, Condello C, Freilich R, Gillies A, Arhar T, Oroz J, Kadavath H, Julien O, Assimon VA, Rauch JN, Dunyak BM, Lee J, Tsai FTF, Wilson MR, Zweckstetter M, ... Dickey CA, et al. Mapping interactions with the chaperone network reveals factors that protect against tau aggregation. Nature Structural & Molecular Biology. 25: 384-393. PMID 29728653 DOI: 10.1038/S41594-018-0057-1 |
0.523 |
|
| 2018 |
Huard DJ, Crowley VM, Du Y, Cordova RA, Sun Z, Tomlin MO, Dickey CA, Koren J, Blair L, Fu H, Blagg BSJ, Lieberman RL. Trifunctional high-throughput screen identifies promising scaffold to inhibit Grp94 and treat myocilin-associated glaucoma. Acs Chemical Biology. PMID 29402077 DOI: 10.1021/Acschembio.7B01083 |
0.803 |
|
| 2017 |
Stothert AR, Suntharalingam A, Tang X, Crowley VM, Mishra SJ, Webster JM, Nordhues BA, Huard DJE, Passaglia CL, Lieberman RL, Blagg BSJ, Blair LJ, Koren J, Dickey CA. Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma. Scientific Reports. 7: 17951. PMID 29263415 DOI: 10.1038/S41598-017-18344-4 |
0.81 |
|
| 2017 |
Woo JA, Liu T, Zhao X, Trotter C, Yrigoin K, Cazzaro S, Narvaez E, Khan H, Witas R, Bukhari A, Makati K, Wang X, Dickey C, Kang DE. Enhanced tau pathology via RanBP9 and Hsp90/Hsc70 chaperone complexes. Human Molecular Genetics. 26: 3973-3988. PMID 29016855 DOI: 10.1093/Hmg/Ddx284 |
0.571 |
|
| 2017 |
Shelton LB, Baker JD, Zheng D, Sullivan LE, Solanki PK, Webster JM, Sun Z, Sabbagh JJ, Nordhues BA, Koren J, Ghosh S, Blagg BSJ, Blair LJ, Dickey CA. Hsp90 activator Aha1 drives production of pathological tau aggregates. Proceedings of the National Academy of Sciences of the United States of America. PMID 28827321 DOI: 10.1073/Pnas.1707039114 |
0.864 |
|
| 2017 |
Baker JD, Shelton LB, Zheng D, Favretto F, Nordhues BA, Darling A, Sullivan LE, Sun Z, Solanki PK, Martin MD, Suntharalingam A, Sabbagh JJ, Becker S, Mandelkow E, Uversky VN, ... ... Dickey CA, et al. Human cyclophilin 40 unravels neurotoxic amyloids. Plos Biology. 15: e2001336. PMID 28654636 DOI: 10.1371/Journal.Pbio.2001336 |
0.85 |
|
| 2017 |
Shelton LB, Baker JD, Zheng D, Ghosh S, Blagg BSJ, Dickey CA, Blair LJ. Aha1 Accelerates Hsp90 Atpase Activity To Drive Tau Aggregation Alzheimers & Dementia. 13: 556. DOI: 10.1016/J.Jalz.2017.07.159 |
0.475 |
|
| 2017 |
Baker JD, Shelton LB, Zheng D, Blair LJ, Koren J, Zweckstetter M, Dickey CA. [P2-168]: PPID CONTROLS TOXIC AMYLOID FORMATION THROUGH PROLINE ISOMERIZATION Alzheimer's & Dementia. 13: P671-P671. DOI: 10.1016/J.Jalz.2017.06.819 |
0.62 |
|
| 2017 |
Baker JD, Breydo L, Dickey CA, Blair LJ, Koren J. [P4-103]: PROLINE ISOMERIZATION CONTROLS TOXIC AMYLOID FORMATION Alzheimer's & Dementia. 13: P1297-P1297. DOI: 10.1016/J.Jalz.2017.06.1969 |
0.62 |
|
| 2016 |
Mishra SJ, Ghosh S, Stothert AR, Dickey CA, Blagg BS. Transformation of the Non-Selective Aminocyclohexanol-Based Hsp90 Inhibitor into a Grp94-Seletive Scaffold. Acs Chemical Biology. PMID 27959508 DOI: 10.1021/Acschembio.6B00747 |
0.37 |
|
| 2016 |
Young ZT, Rauch JN, Assimon VA, Jinwal UK, Ahn M, Li X, Dunyak BM, Ahmad A, Carlson GA, Srinivasan SR, Zuiderweg ER, Dickey CA, Gestwicki JE. Stabilizing the Hsp70-Tau Complex Promotes Turnover in Models of Tauopathy. Cell Chemical Biology. PMID 27499529 DOI: 10.1016/J.Chembiol.2016.04.014 |
0.498 |
|
| 2016 |
Ouimet CM, Shao H, Rauch JN, Dawod M, Nordhues BA, Dickey CA, Gestwicki JE, Kennedy RT. Protein Cross-linking Capillary Electrophoresis (PXCE) for Protein-Protein Interaction Analysis. Analytical Chemistry. PMID 27434096 DOI: 10.1021/Acs.Analchem.6B02126 |
0.326 |
|
| 2016 |
Zheng D, Sabbagh JJ, Blair LJ, Darling AL, Wen X, Dickey CA. MicroRNA-511 binds to FKBP5 mRNA, which encodes a chaperone protein, and regulates neuronal differentiation. The Journal of Biological Chemistry. PMID 27334923 DOI: 10.1074/Jbc.M116.727941 |
0.763 |
|
| 2016 |
Fontaine SN, Zheng D, Sabbagh JJ, Martin MD, Chaput D, Darling A, Trotter JH, Stothert AR, Nordhues BA, Lussier A, Baker J, Shelton L, Kahn M, Blair LJ, Stevens SM, ... Dickey CA, et al. DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins. The Embo Journal. PMID 27261198 DOI: 10.15252/Embj.201593489 |
0.818 |
|
| 2016 |
Martin MD, Baker JD, Suntharalingam A, Nordhues BA, Shelton LB, Zheng D, Sabbagh JJ, Haystead TA, Gestwicki JE, Dickey CA. Inhibition of Both Hsp70 Activity and Tau Aggregation In Vitro Best Predicts Tau Lowering Activity of Small Molecules. Acs Chemical Biology. PMID 27177119 DOI: 10.1021/Acschembio.6B00223 |
0.553 |
|
| 2016 |
Fontaine SN, Martin MD, Dickey CA. Neurodegeneration and the Heat Shock Protein 70 Machinery: Implications for Therapeutic Development. Current Topics in Medicinal Chemistry. PMID 27072702 DOI: 10.2174/1568026616666160413140741 |
0.435 |
|
| 2016 |
Crowley VM, Khandelwal A, Mishra S, Stothert AR, Huard DJ, Zhao J, Muth A, Duerfeldt AS, Kizziah JL, Lieberman RL, Dickey CA, Blagg BS. Development of Glucose Regulated Protein 94-Selective Inhibitors based on the BnIm and Radamide Scaffold. Journal of Medicinal Chemistry. PMID 27003516 DOI: 10.1021/Acs.Jmedchem.6B00085 |
0.376 |
|
| 2016 |
Zhang YJ, Gendron TF, Grima JC, Sasaguri H, Jansen-West K, Xu YF, Katzman RB, Gass J, Murray ME, Shinohara M, Lin WL, Garrett A, Stankowski JN, Daughrity L, Tong J, ... ... Dickey CA, et al. C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins. Nature Neuroscience. PMID 26998601 DOI: 10.1038/Nn.4272 |
0.535 |
|
| 2016 |
Sabbagh JJ, Dickey CA. The Metamorphic Nature of the Tau Protein: Dynamic Flexibility Comes at a Cost. Frontiers in Neuroscience. 10: 3. PMID 26834532 DOI: 10.3389/fnins.2016.00003 |
0.507 |
|
| 2016 |
Sabbagh JJ, Fontaine SN, Shelton LB, Blair LJ, Hunt JB, Zhang B, Lee DC, Lloyd JD, Dickey CA. Non-contact rotational head injury produces transient cognitive deficits but lasting neuropathological changes. Journal of Neurotrauma. PMID 26739819 DOI: 10.1089/neu.2015.4288 |
0.772 |
|
| 2015 |
Hunt JB, Nash KR, Placides D, Moran P, Selenica ML, Abuqalbeen F, Ratnasamy K, Slouha N, Rodriguez-Ospina S, Savlia M, Ranaweera Y, Reid P, Dickey CA, Uricia R, Yang CG, et al. Sustained Arginase 1 Expression Modulates Pathological Tau Deposits in a Mouse Model of Tauopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 14842-60. PMID 26538654 DOI: 10.1523/Jneurosci.3959-14.2015 |
0.771 |
|
| 2015 |
Lindberg I, Shorter J, Wiseman RL, Chiti F, Dickey CA, McLean PJ. Chaperones in Neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13853-9. PMID 26468185 DOI: 10.1523/Jneurosci.2600-15.2015 |
0.402 |
|
| 2015 |
Stothert AR, Fontaine SN, Sabbagh JJ, Dickey CA. Targeting the ER-autophagy system in the trabecular meshwork to treat glaucoma. Experimental Eye Research. PMID 26302411 DOI: 10.1016/j.exer.2015.08.017 |
0.348 |
|
| 2015 |
Fontaine SN, Martin MD, Akoury E, Assimon VA, Borysov S, Nordhues BA, Sabbagh JJ, Cockman M, Gestwicki JE, Zweckstetter M, Dickey CA. The active Hsc70/tau complex can be exploited to enhance tau turnover without damaging microtubule dynamics. Human Molecular Genetics. 24: 3971-81. PMID 25882706 DOI: 10.1093/Hmg/Ddv135 |
0.546 |
|
| 2015 |
Fontaine SN, Rauch JN, Nordhues BA, Assimon VA, Stothert AR, Jinwal UK, Sabbagh JJ, Chang L, Stevens SM, Zuiderweg ER, Gestwicki JE, Dickey CA. Isoform-selective Genetic Inhibition of Constitutive Cytosolic Hsp70 Activity Promotes Client Tau Degradation Using an Altered Co-chaperone Complement. The Journal of Biological Chemistry. 290: 13115-27. PMID 25864199 DOI: 10.1074/Jbc.M115.637595 |
0.501 |
|
| 2015 |
Blair LJ, Frauen HD, Zhang B, Nordhues BA, Bijan S, Lin YC, Zamudio F, Hernandez LD, Sabbagh JJ, Selenica ML, Dickey CA. Tau depletion prevents progressive blood-brain barrier damage in a mouse model of tauopathy. Acta Neuropathologica Communications. 3: 8. PMID 25775028 DOI: 10.1186/s40478-015-0186-2 |
0.809 |
|
| 2015 |
Fontaine SN, Sabbagh JJ, Baker J, Martinez-Licha CR, Darling A, Dickey CA. Cellular factors modulating the mechanism of tau protein aggregation. Cellular and Molecular Life Sciences : Cmls. 72: 1863-79. PMID 25666877 DOI: 10.1007/S00018-015-1839-9 |
0.539 |
|
| 2015 |
Blair LJ, Baker JD, Sabbagh JJ, Dickey CA. The emerging role of peptidyl-prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease. Journal of Neurochemistry. 133: 1-13. PMID 25628064 DOI: 10.1111/jnc.13033 |
0.84 |
|
| 2015 |
Martin MD, Calcul L, Smith C, Jinwal UK, Fontaine SN, Darling A, Seeley K, Wojtas L, Narayan M, Gestwicki JE, Smith GR, Reitz AB, Baker BJ, Dickey CA. Synthesis, stereochemical analysis, and derivatization of myricanol provide new probes that promote autophagic tau clearance. Acs Chemical Biology. 10: 1099-109. PMID 25588114 DOI: 10.1021/Cb501013W |
0.465 |
|
| 2014 |
Sabbagh JJ, O'Leary JC, Blair LJ, Klengel T, Nordhues BA, Fontaine SN, Binder EB, Dickey CA. Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency. Plos One. 9: e107241. PMID 25191701 DOI: 10.1371/journal.pone.0107241 |
0.772 |
|
| 2014 |
Selenica ML, Davtyan H, Housley SB, Blair LJ, Gillies A, Nordhues BA, Zhang B, Liu J, Gestwicki JE, Lee DC, Gordon MN, Morgan D, Dickey CA. Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis. Journal of Neuroinflammation. 11: 152. PMID 25183004 DOI: 10.1186/S12974-014-0152-0 |
0.827 |
|
| 2014 |
Blair LJ, Sabbagh JJ, Dickey CA. Targeting Hsp90 and its co-chaperones to treat Alzheimer's disease. Expert Opinion On Therapeutic Targets. 18: 1219-32. PMID 25069659 DOI: 10.1517/14728222.2014.943185 |
0.833 |
|
| 2014 |
Stothert AR, Suntharalingam A, Huard DJ, Fontaine SN, Crowley VM, Mishra S, Blagg BS, Lieberman RL, Dickey CA. Exploiting the interaction between Grp94 and aggregated myocilin to treat glaucoma. Human Molecular Genetics. 23: 6470-80. PMID 25027323 DOI: 10.1093/Hmg/Ddu367 |
0.406 |
|
| 2014 |
Karagöz GE, Duarte AM, Akoury E, Ippel H, Biernat J, Morán Luengo T, Radli M, Didenko T, Nordhues BA, Veprintsev DB, Dickey CA, Mandelkow E, Zweckstetter M, Boelens R, Madl T, et al. Hsp90-Tau complex reveals molecular basis for specificity in chaperone action. Cell. 156: 963-74. PMID 24581495 DOI: 10.1016/J.Cell.2014.01.037 |
0.44 |
|
| 2014 |
Orwig SD, Chi PV, Du Y, Hill SE, Cavitt MA, Suntharalingam A, Turnage KC, Dickey CA, France S, Fu H, Lieberman RL. Ligands for glaucoma-associated myocilin discovered by a generic binding assay. Acs Chemical Biology. 9: 517-25. PMID 24279319 DOI: 10.1021/Cb4007776 |
0.34 |
|
| 2013 |
Blair LJ, Zhang B, Dickey CA. Potential synergy between tau aggregation inhibitors and tau chaperone modulators. Alzheimer's Research & Therapy. 5: 41. PMID 24041111 DOI: 10.1186/alzrt207 |
0.84 |
|
| 2013 |
O'Leary JC, Zhang B, Koren J, Blair L, Dickey CA. The role of FKBP5 in mood disorders: action of FKBP5 on steroid hormone receptors leads to questions about its evolutionary importance. Cns & Neurological Disorders Drug Targets. 12: 1157-62. PMID 24040820 DOI: 10.2174/187152731131200121 |
0.781 |
|
| 2013 |
Blair LJ, Nordhues BA, Hill SE, Scaglione KM, O'Leary JC, Fontaine SN, Breydo L, Zhang B, Li P, Wang L, Cotman C, Paulson HL, Muschol M, Uversky VN, Klengel T, ... ... Dickey CA, et al. Accelerated neurodegeneration through chaperone-mediated oligomerization of tau. The Journal of Clinical Investigation. 123: 4158-69. PMID 23999428 DOI: 10.1172/Jci69003 |
0.848 |
|
| 2013 |
Smith MC, Scaglione KM, Assimon VA, Patury S, Thompson AD, Dickey CA, Southworth DR, Paulson HL, Gestwicki JE, Zuiderweg ER. The E3 ubiquitin ligase CHIP and the molecular chaperone Hsc70 form a dynamic, tethered complex. Biochemistry. 52: 5354-64. PMID 23865999 DOI: 10.1021/Bi4009209 |
0.301 |
|
| 2013 |
Jinwal UK, Koren J, Dickey CA. Reconstructing the Hsp90/Tau Machine. Current Enzyme Inhibition. 9: 41-45. PMID 23798910 DOI: 10.2174/1573408011309010006 |
0.737 |
|
| 2013 |
Abisambra JF, Jinwal UK, Blair LJ, O'Leary JC, Li Q, Brady S, Wang L, Guidi CE, Zhang B, Nordhues BA, Cockman M, Suntharalingham A, Li P, Jin Y, Atkins CA, ... Dickey CA, et al. Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9498-507. PMID 23719816 DOI: 10.1523/Jneurosci.5397-12.2013 |
0.852 |
|
| 2013 |
Abisambra J, Jinwal UK, Miyata Y, Rogers J, Blair L, Li X, Seguin SP, Wang L, Jin Y, Bacon J, Brady S, Cockman M, Guidi C, Zhang J, Koren J, ... ... Dickey CA, et al. Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau. Biological Psychiatry. 74: 367-74. PMID 23607970 DOI: 10.1016/J.Biopsych.2013.02.027 |
0.84 |
|
| 2013 |
Lee DC, Ruiz CR, Lebson L, Selenica ML, Rizer J, Hunt JB, Rojiani R, Reid P, Kammath S, Nash K, Dickey CA, Gordon M, Morgan D. Aging enhances classical activation but mitigates alternative activation in the central nervous system. Neurobiology of Aging. 34: 1610-20. PMID 23481567 DOI: 10.1016/J.Neurobiolaging.2012.12.014 |
0.638 |
|
| 2013 |
Miyata Y, Li X, Lee HF, Jinwal UK, Srinivasan SR, Seguin SP, Young ZT, Brodsky JL, Dickey CA, Sun D, Gestwicki JE. Synthesis and initial evaluation of YM-08, a blood-brain barrier permeable derivative of the heat shock protein 70 (Hsp70) inhibitor MKT-077, which reduces tau levels. Acs Chemical Neuroscience. 4: 930-9. PMID 23472668 DOI: 10.1021/Cn300210G |
0.441 |
|
| 2013 |
Chiosis G, Dickey CA, Johnson JL. A global view of Hsp90 functions. Nature Structural & Molecular Biology. 20: 1-4. PMID 23288357 DOI: 10.1038/Nsmb.2481 |
0.316 |
|
| 2013 |
Jinwal UK, Akoury E, Abisambra JF, O'Leary JC, Thompson AD, Blair LJ, Jin Y, Bacon J, Nordhues BA, Cockman M, Zhang J, Li P, Zhang B, Borysov S, Uversky VN, ... ... Dickey CA, et al. Imbalance of Hsp70 family variants fosters tau accumulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1450-9. PMID 23271055 DOI: 10.1096/Fj.12-220889 |
0.847 |
|
| 2013 |
Selenica ML, Brownlow M, Jimenez JP, Lee DC, Pena G, Dickey CA, Gordon MN, Morgan D. Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy. Neuro-Degenerative Diseases. 11: 165-81. PMID 22796753 DOI: 10.1159/000337230 |
0.734 |
|
| 2013 |
Nakamura M, Kaneko S, Ito H, Jiang S, Fujita K, Wate R, Nakano S, Fujisawa J, Kusaka H, Flunkert S, Hierzer M, Löffler T, Rabl R, Neddens J, Duller S, ... ... Dickey CA, et al. Contents Vol. 11, 2013 Neurodegenerative Diseases. 11. DOI: 10.1159/000350668 |
0.497 |
|
| 2013 |
Blair L, Nordhues B, Hill S, Scaglione KM, O'Leary J, Breydo L, Bo Z, Li P, Wang L, Cotman C, Paulson H, Muschol M, Uversky V, Klengel T, Binder E, ... ... Dickey C, et al. The Hsp90 co-chaperone FKBP51 produces neurotoxic tau oligomers: Implication for aging and Alzheimer's disease Alzheimers & Dementia. 9: 173. DOI: 10.1016/J.Jalz.2013.05.279 |
0.498 |
|
| 2013 |
Zhang B, Blair L, Wang L, Dickey C. Blood-brain barrier permeability observed in rTg4510 tau mouse model Alzheimers & Dementia. 9: 719. DOI: 10.1016/J.Jalz.2013.05.1434 |
0.341 |
|
| 2013 |
Selenica M, Housley S, Blair L, Davtyan H, Sanneh A, Mouse T, Lee D, Gordon MN, Morgan D, Dickey C. P2-415: Immunotherapy targeting human wild type and P301L tau results in an immune response and changes in tau levels in an rTG4510 mouse model Alzheimer's & Dementia. 9: P509-P510. DOI: 10.1016/J.Jalz.2013.05.1065 |
0.39 |
|
| 2013 |
Fontaine S, Jinwal U, Thompson A, Gestwicki J, Dickey C. O2-01-06: The nucleotide binding domain of heat shock cognate protein 70 (Hsc70) regulates tau clearance and stability Alzheimer's & Dementia. 9: P315-P315. DOI: 10.1016/J.Jalz.2013.04.140 |
0.388 |
|
| 2012 |
Miyata Y, Rauch JN, Jinwal UK, Thompson AD, Srinivasan S, Dickey CA, Gestwicki JE. Cysteine reactivity distinguishes redox sensing by the heat-inducible and constitutive forms of heat shock protein 70. Chemistry & Biology. 19: 1391-9. PMID 23177194 DOI: 10.1016/J.Chembiol.2012.07.026 |
0.426 |
|
| 2012 |
Suntharalingam A, Abisambra JF, O'Leary JC, Koren J, Zhang B, Joe MK, Blair LJ, Hill SE, Jinwal UK, Cockman M, Duerfeldt AS, Tomarev S, Blagg BS, Lieberman RL, Dickey CA. Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism. The Journal of Biological Chemistry. 287: 40661-9. PMID 23035116 DOI: 10.1074/Jbc.M112.384800 |
0.797 |
|
| 2012 |
Calcul L, Zhang B, Jinwal UK, Dickey CA, Baker BJ. Natural products as a rich source of tau-targeting drugs for Alzheimer's disease. Future Medicinal Chemistry. 4: 1751-61. PMID 22924511 DOI: 10.4155/Fmc.12.124 |
0.46 |
|
| 2012 |
Thompson AD, Scaglione KM, Prensner J, Gillies AT, Chinnaiyan A, Paulson HL, Jinwal UK, Dickey CA, Gestwicki JE. Analysis of the tau-associated proteome reveals that exchange of Hsp70 for Hsp90 is involved in tau degradation. Acs Chemical Biology. 7: 1677-86. PMID 22769591 DOI: 10.1021/Cb3002599 |
0.564 |
|
| 2012 |
Jinwal UK, Abisambra JF, Zhang J, Dharia S, O'Leary JC, Patel T, Braswell K, Jani T, Gestwicki JE, Dickey CA. Cdc37/Hsp90 protein complex disruption triggers an autophagic clearance cascade for TDP-43 protein. The Journal of Biological Chemistry. 287: 24814-20. PMID 22674575 DOI: 10.1074/Jbc.M112.367268 |
0.758 |
|
| 2012 |
Koren J, Miyata Y, Kiray J, O'Leary JC, Nguyen L, Guo J, Blair LJ, Li X, Li X, Jinwal UK, Cheng JQ, Gestwicki JE, Dickey CA. Rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistance. Plos One. 7: e35566. PMID 22563386 DOI: 10.1371/Journal.Pone.0035566 |
0.771 |
|
| 2012 |
Congdon EE, Wu JW, Myeku N, Figueroa YH, Herman M, Marinec PS, Gestwicki JE, Dickey CA, Yu WH, Duff KE. Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivo. Autophagy. 8: 609-22. PMID 22361619 DOI: 10.4161/Auto.19048 |
0.515 |
|
| 2012 |
Abisambra JF, Jinwal UK, Suntharalingam A, Arulselvam K, Brady S, Cockman M, Jin Y, Zhang B, Dickey CA. DnaJA1 antagonizes constitutive Hsp70-mediated stabilization of tau. Journal of Molecular Biology. 421: 653-61. PMID 22343013 DOI: 10.1016/J.Jmb.2012.02.003 |
0.789 |
|
| 2012 |
Koren J, Miyata Y, Kiray J, O'Leary JC, Nguyen L, Guo J, Blair LJ, Li X, Jinwal UK, Cheng JQ, Gestwicki JE, Dickey CA. Correction: Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance Plos One. 7. DOI: 10.1371/Annotation/7493E5D2-4C1A-43Eb-A83F-16814861Ff13 |
0.552 |
|
| 2012 |
Abisambra J, Brady S, Wang L, Arulselvam K, Cockman M, Blair L, Guidi C, Dickey C. O2-09-01: Endoplasmic reticulum (ER) stress and abnormal tau converge in a ubiquitin-related vicious cycle: Early events in neuronal damage Alzheimer's & Dementia. 8: P252-P252. DOI: 10.1016/J.Jalz.2012.05.672 |
0.677 |
|
| 2012 |
Voss K, Abisambra J, O'Leary J, Blair L, Jinwal U, Dickey C. O1-07-01: FKBP51 connects tau to the systemic stress response network through Hsp90 Alzheimer's & Dementia. 8: P97-P97. DOI: 10.1016/J.Jalz.2012.05.239 |
0.667 |
|
| 2011 |
Abisambra JF, Jinwal UK, Jones JR, Blair LJ, Koren J, Dickey CA. Exploiting the diversity of the heat-shock protein family for primary and secondary tauopathy therapeutics. Current Neuropharmacology. 9: 623-31. PMID 22654720 DOI: 10.2174/157015911798376226 |
0.837 |
|
| 2011 |
Daily JL, Nash K, Jinwal U, Golde T, Rogers J, Peters MM, Burdine RD, Dickey C, Banko JL, Weeber EJ. Adeno-associated virus-mediated rescue of the cognitive defects in a mouse model for Angelman syndrome. Plos One. 6: e27221. PMID 22174738 DOI: 10.1371/Journal.Pone.0027221 |
0.354 |
|
| 2011 |
Trotter JH, Klein M, Jinwal UK, Abisambra JF, Dickey CA, Tharkur J, Masiulis I, Ding J, Locke KG, Rickman CB, Birch DG, Weeber EJ, Herz J. ApoER2 function in the establishment and maintenance of retinal synaptic connectivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14413-23. PMID 21976526 DOI: 10.1523/Jneurosci.3135-11.2011 |
0.634 |
|
| 2011 |
Voss K, Koren J, Dickey CA. The earliest tau dysfunction in Alzheimer's disease? Tau phosphorylated at s422 as a toxic seed. The American Journal of Pathology. 179: 2148-51. PMID 21964186 DOI: 10.1016/J.Ajpath.2011.08.020 |
0.721 |
|
| 2011 |
O'Leary JC, Dharia S, Blair LJ, Brady S, Johnson AG, Peters M, Cheung-Flynn J, Cox MB, de Erausquin G, Weeber EJ, Jinwal UK, Dickey CA. A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51. Plos One. 6: e24840. PMID 21935478 DOI: 10.1371/journal.pone.0024840 |
0.765 |
|
| 2011 |
Storer CL, Dickey CA, Galigniana MD, Rein T, Cox MB. FKBP51 and FKBP52 in signaling and disease. Trends in Endocrinology and Metabolism: Tem. 22: 481-90. PMID 21889356 DOI: 10.1016/j.tem.2011.08.001 |
0.363 |
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| 2011 |
Miyata Y, Koren J, Kiray J, Dickey CA, Gestwicki JE. Molecular chaperones and regulation of tau quality control: strategies for drug discovery in tauopathies. Future Medicinal Chemistry. 3: 1523-37. PMID 21882945 DOI: 10.4155/Fmc.11.88 |
0.735 |
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| 2011 |
Rousaki A, Miyata Y, Jinwal UK, Dickey CA, Gestwicki JE, Zuiderweg ER. Allosteric drugs: the interaction of antitumor compound MKT-077 with human Hsp70 chaperones. Journal of Molecular Biology. 411: 614-32. PMID 21708173 DOI: 10.1016/J.Jmb.2011.06.003 |
0.427 |
|
| 2011 |
O'Leary JC, Koren J, Dickey CA. Neuronal life span versus health span: principles of natural selection at work in the degenerating brain. Journal of Molecular Neuroscience : Mn. 45: 467-72. PMID 21559875 DOI: 10.1007/S12031-011-9540-4 |
0.685 |
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| 2011 |
Koren J, Jinwal UK, Davey Z, Kiray J, Arulselvam K, Dickey CA. Bending tau into shape: the emerging role of peptidyl-prolyl isomerases in tauopathies. Molecular Neurobiology. 44: 65-70. PMID 21523562 DOI: 10.1007/S12035-011-8182-4 |
0.741 |
|
| 2011 |
Jinwal UK, Trotter JH, Abisambra JF, Koren J, Lawson LY, Vestal GD, O'Leary JC, Johnson AG, Jin Y, Jones JR, Li Q, Weeber EJ, Dickey CA. The Hsp90 kinase co-chaperone Cdc37 regulates tau stability and phosphorylation dynamics. The Journal of Biological Chemistry. 286: 16976-83. PMID 21367866 DOI: 10.1074/Jbc.M110.182493 |
0.832 |
|
| 2011 |
Jones JR, Lebar MD, Jinwal UK, Abisambra JF, Koren J, Blair L, O'Leary JC, Davey Z, Trotter J, Johnson AG, Weeber E, Eckman CB, Baker BJ, Dickey CA. The diarylheptanoid (+)-aR,11S-myricanol and two flavones from bayberry (Myrica cerifera) destabilize the microtubule-associated protein tau. Journal of Natural Products. 74: 38-44. PMID 21141876 DOI: 10.1021/Np100572Z |
0.84 |
|
| 2011 |
Evans CG, Jinwal UK, Makley LN, Dickey CA, Gestwicki JE. Identification of dihydropyridines that reduce cellular tau levels. Chemical Communications (Cambridge, England). 47: 529-31. PMID 21082080 DOI: 10.1039/C0Cc02253E |
0.474 |
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| 2011 |
Jinwal UK, Dickey CA. Cell-based assays for regulators of tau biology. Methods in Molecular Biology (Clifton, N.J.). 670: 93-108. PMID 20967586 DOI: 10.1007/978-1-60761-744-0_8 |
0.44 |
|
| 2011 |
Koren J, Miyata Y, Kiray J, Guo J, Gestwicki J, Cheng JQ, Dickey C. Abstract 2094: Hsp70 inhibitors overcome tamoxifen resistance, in cell culture model Cancer Research. 71: 2094-2094. DOI: 10.1158/1538-7445.Am2011-2094 |
0.619 |
|
| 2011 |
Abisambra J, Cannon A, O'Leary J, Brady S, Espinosa A, Jinwal U, Koren J, Blair L, Lewis J, Dickey C. O4-04-08: Neuronal tau-specific stress induction of molecular chaperones: The failure of a coping mechanism Alzheimer's & Dementia. 7: S691-S691. DOI: 10.1016/J.Jalz.2011.05.1996 |
0.796 |
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| 2011 |
Jinwal U, Abisambra J, Koren J, O'Leary J, Blair L, Hill S, Trotter J, Mushcol M, Weeber E, Gestwicki J, Dickey C. P3-124: Exploiting the diversity of the chaperone repertoire to treat tauopathies Alzheimer's & Dementia. 7: S554-S554. DOI: 10.1016/J.Jalz.2011.05.1565 |
0.736 |
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| 2011 |
Hill SE, Miti T, Jones J, Davey Z, Abisambra JF, Dickey C, Muschol M. Modulation of Tau Fibril Growth in Vitro by Hsp27 vs FKBP51 and their Mutants Biophysical Journal. 100: 540a. DOI: 10.1016/J.Bpj.2010.12.3147 |
0.76 |
|
| 2010 |
Abisambra JF, Blair LJ, Hill SE, Jones JR, Kraft C, Rogers J, Koren J, Jinwal UK, Lawson L, Johnson AG, Wilcock D, O'Leary JC, Jansen-West K, Muschol M, Golde TE, ... ... Dickey CA, et al. Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15374-82. PMID 21084594 DOI: 10.1523/Jneurosci.3155-10.2010 |
0.841 |
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| 2010 |
O'Leary JC, Li Q, Marinec P, Blair LJ, Congdon EE, Johnson AG, Jinwal UK, Koren J, Jones JR, Kraft C, Peters M, Abisambra JF, Duff KE, Weeber EJ, Gestwicki JE, ... Dickey CA, et al. Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden. Molecular Neurodegeneration. 5: 45. PMID 21040568 DOI: 10.1186/1750-1326-5-45 |
0.839 |
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| 2010 |
Carty N, Lee D, Dickey C, Ceballos-Diaz C, Jansen-West K, Golde TE, Gordon MN, Morgan D, Nash K. Convection-enhanced delivery and systemic mannitol increase gene product distribution of AAV vectors 5, 8, and 9 and increase gene product in the adult mouse brain. Journal of Neuroscience Methods. 194: 144-53. PMID 20951738 DOI: 10.1016/J.Jneumeth.2010.10.010 |
0.636 |
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| 2010 |
Lee DC, Rizer J, Selenica ML, Reid P, Kraft C, Johnson A, Blair L, Gordon MN, Dickey CA, Morgan D. LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice. Journal of Neuroinflammation. 7: 56. PMID 20846376 DOI: 10.1186/1742-2094-7-56 |
0.816 |
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| 2010 |
Lebson L, Nash K, Kamath S, Herber D, Carty N, Lee DC, Li Q, Szekeres K, Jinwal U, Koren J, Dickey CA, Gottschall PE, Morgan D, Gordon MN. Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9651-8. PMID 20660248 DOI: 10.1523/Jneurosci.0329-10.2010 |
0.765 |
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| 2010 |
Jinwal UK, Koren J, O'Leary JC, Jones JR, Abisambra JF, Dickey CA. Hsp70 ATPase Modulators as Therapeutics for Alzheimer's and other Neurodegenerative Diseases. Molecular and Cellular Pharmacology. 2: 43-46. PMID 20523917 DOI: 10.4255/mcpharmacol.10.06 |
0.827 |
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| 2010 |
Jinwal UK, O'Leary JC, Borysov SI, Jones JR, Li Q, Koren J, Abisambra JF, Vestal GD, Lawson LY, Johnson AG, Blair LJ, Jin Y, Miyata Y, Gestwicki JE, Dickey CA. Hsc70 rapidly engages tau after microtubule destabilization. The Journal of Biological Chemistry. 285: 16798-805. PMID 20308058 DOI: 10.1074/Jbc.M110.113753 |
0.842 |
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| 2010 |
Jinwal UK, Koren J, Borysov SI, Schmid AB, Abisambra JF, Blair LJ, Johnson AG, Jones JR, Shults CL, O'Leary JC, Jin Y, Buchner J, Cox MB, Dickey CA. The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 591-9. PMID 20071522 DOI: 10.1523/Jneurosci.4815-09.2010 |
0.849 |
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| 2010 |
Azorsa DO, Robeson RH, Frost D, Meec hoovet B, Brautigam GR, Dickey C, Beaudry C, Basu GD, Holz DR, Hernandez JA, Bisanz KM, Gwinn L, Grover A, Rogers J, Reiman EM, et al. High-content siRNA screening of the kinome identifies kinases involved in Alzheimer's disease-related tau hyperphosphorylation. Bmc Genomics. 11: 25. PMID 20067632 DOI: 10.1186/1471-2164-11-25 |
0.609 |
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| 2010 |
Koren J, Jinwal UK, Jin Y, O'Leary J, Jones JR, Johnson AG, Blair LJ, Abisambra JF, Chang L, Miyata Y, Cheng AM, Guo J, Cheng JQ, Gestwicki JE, Dickey CA. Facilitating Akt clearance via manipulation of Hsp70 activity and levels. The Journal of Biological Chemistry. 285: 2498-505. PMID 19889640 DOI: 10.1074/Jbc.M109.057208 |
0.798 |
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| 2010 |
Dickey CA, O'Leary JC, Borysov S, Koren J, Jones J, Lawson L, Blair L, Jin Y, Lawson L, Abisambra JF, Li Q, Jinwal UK. P1-370: The early involvement of chaperones in tau pathogenesis Alzheimer's & Dementia. 6: S280-S280. DOI: 10.1016/J.Jalz.2010.05.924 |
0.786 |
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| 2010 |
Abisambra JF, Blair LJ, Jones JR, Kraft C, Hill S, Rogers J, Koren J, Jinwal UK, Lawson L, Johnson AG, Jansen-West K, Muschol M, Banko J, Golde T, Weeber EJ, ... Dickey CA, et al. P3-425: Chaperone-mediated modulation of tau aggregation correlates with modifications in tau pathology and synaptic plasticity Alzheimer's & Dementia. 6: S577-S577. DOI: 10.1016/J.Jalz.2010.05.1968 |
0.797 |
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| 2009 |
Jinwal UK, Miyata Y, Koren J, Jones JR, Trotter JH, Chang L, O'Leary J, Morgan D, Lee DC, Shults CL, Rousaki A, Weeber EJ, Zuiderweg ER, Gestwicki JE, Dickey CA. Chemical manipulation of hsp70 ATPase activity regulates tau stability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12079-88. PMID 19793966 DOI: 10.1523/Jneurosci.3345-09.2009 |
0.769 |
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| 2009 |
Koren J, Jinwal UK, Lee DC, Jones JR, Shults CL, Johnson AG, Anderson LJ, Dickey CA. Chaperone signalling complexes in Alzheimer's disease. Journal of Cellular and Molecular Medicine. 13: 619-30. PMID 19449461 DOI: 10.1111/J.1582-4934.2008.00557.X |
0.763 |
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| 2009 |
Dickey C, Kraft C, Jinwal U, Koren J, Johnson A, Anderson L, Lebson L, Lee D, Dickson D, de Silva R, Binder LI, Morgan D, Lewis J. Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy. The American Journal of Pathology. 174: 228-38. PMID 19074615 DOI: 10.2353/Ajpath.2009.080764 |
0.835 |
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| 2009 |
Dickey CA, Jinwal UK, Koren J, O'Leary J, Anderson L, Jones J, Shults C, Jin Y, Johnson A, Abisambra J, Morgan D, Lee DC, Chang L, Miyata Y, Thompson A, et al. P2-198: Chemical manipulation of Hsp70 activity regulates tau processing Alzheimer's & Dementia. 5: P319-P319. DOI: 10.1016/J.Jalz.2009.04.510 |
0.813 |
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| 2008 |
Dickey CA, Koren J, Zhang YJ, Xu YF, Jinwal UK, Birnbaum MJ, Monks B, Sun M, Cheng JQ, Patterson C, Bailey RM, Dunmore J, Soresh S, Leon C, Morgan D, et al. Akt and CHIP coregulate tau degradation through coordinated interactions. Proceedings of the National Academy of Sciences of the United States of America. 105: 3622-7. PMID 18292230 DOI: 10.1073/Pnas.0709180105 |
0.807 |
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| 2008 |
Dickey CA, Koren J, Zhang Y, Xu Y, Jinwal U, Bailey R, Dunmore J, Birnbaum M, Morgan D, Petrucelli L. O1-06-03: Akt functions to regulate the chaperone complex and attenuate Tau degradation Alzheimer's & Dementia. 4: T120-T120. DOI: 10.1016/J.Jalz.2008.05.258 |
0.734 |
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| 2008 |
Robeson RH, Brautigam GR, Frost D, Azorsa D, Dickey C, Beaudry C, Basu G, Holz D, Hernandez J, Bisanz K, Gwinn L, Meechoovet B, Grover A, Rogers J, Reiman EM, et al. P2-141: Unraveling the process of tau hyperphosphorylation one gene at a time Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1214 |
0.349 |
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| 2007 |
Dickey CA, Petrucelli L. Commentary on "Cytoskeletal modulators and pleiotropic strategies for Alzheimer drug discovery." The last stand: the dichotomy of chaperone function in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 3: 3-6. PMID 19595909 DOI: 10.1016/J.Jalz.2006.09.001 |
0.536 |
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| 2007 |
Zhang YJ, Xu YF, Dickey CA, Buratti E, Baralle F, Bailey R, Pickering-Brown S, Dickson D, Petrucelli L. Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10530-4. PMID 17898224 DOI: 10.1523/Jneurosci.3421-07.2007 |
0.356 |
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| 2007 |
Dickey CA, Kamal A, Lundgren K, Klosak N, Bailey RM, Dunmore J, Ash P, Shoraka S, Zlatkovic J, Eckman CB, Patterson C, Dickson DW, Nahman NS, Hutton M, Burrows F, et al. The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins. The Journal of Clinical Investigation. 117: 648-58. PMID 17304350 DOI: 10.1172/Jci29715 |
0.672 |
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| 2007 |
Dickey CA, Patterson C, Dickson D, Petrucelli L. Brain CHIP: removing the culprits in neurodegenerative disease. Trends in Molecular Medicine. 13: 32-8. PMID 17127096 DOI: 10.1016/J.Molmed.2006.11.003 |
0.477 |
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| 2007 |
Karlnoski R, Wilcock D, Dickey C, Ronan V, Gordon MN, Zhang W, Morgan D, Taglialatela G. Up-regulation of Bcl-2 in APP transgenic mice is associated with neuroprotection Neurobiology of Disease. 25: 179-188. PMID 17067805 DOI: 10.1016/J.Nbd.2006.09.007 |
0.722 |
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| 2006 |
Dickey CA, Petrucelli L. Current strategies for the treatment of Alzheimer's disease and other tauopathies. Expert Opinion On Therapeutic Targets. 10: 665-76. PMID 16981824 DOI: 10.1517/14728222.10.5.665 |
0.525 |
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| 2006 |
Dickey CA, Ash P, Klosak N, Lee WC, Petrucelli L, Hutton M, Eckman CB. Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression. Molecular Neurodegeneration. 1: 6. PMID 16930453 DOI: 10.1186/1750-1326-1-6 |
0.637 |
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| 2006 |
Baker M, Mackenzie IR, Pickering-Brown SM, Gass J, Rademakers R, Lindholm C, Snowden J, Adamson J, Sadovnick AD, Rollinson S, Cannon A, Dwosh E, Neary D, Melquist S, Richardson A, ... ... Dickey CA, et al. Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17. Nature. 442: 916-9. PMID 16862116 DOI: 10.1038/Nature05016 |
0.806 |
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| 2006 |
Dickey CA, Yue M, Lin WL, Dickson DW, Dunmore JH, Lee WC, Zehr C, West G, Cao S, Clark AM, Caldwell GA, Caldwell KA, Eckman C, Patterson C, Hutton M, et al. Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6985-96. PMID 16807328 DOI: 10.1523/Jneurosci.0746-06.2006 |
0.676 |
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| 2006 |
Lee WC, Tsoi YK, Dickey CA, Delucia MW, Dickson DW, Eckman CB. Suppression of galactosylceramidase (GALC) expression in the twitcher mouse model of globoid cell leukodystrophy (GLD) is caused by nonsense-mediated mRNA decay (NMD). Neurobiology of Disease. 23: 273-80. PMID 16759875 DOI: 10.1016/J.Nbd.2006.03.005 |
0.344 |
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| 2006 |
Dickey CA, Dunmore J, Lu B, Wang JW, Lee WC, Kamal A, Burrows F, Eckman C, Hutton M, Petrucelli L. HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sites. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 753-5. PMID 16464956 DOI: 10.1096/Fj.05-5343Fje |
0.666 |
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| 2006 |
Baker JD, Shelton LB, Zheng D, Dickey CA, Blair LJ. P1-231: PROLYL-ISOMERASES UNTANGLE TAU AGGREGATES AND PREVENT TAU PATHOLOGY Alzheimer's & Dementia. 14: P367-P367. DOI: 10.1016/j.jalz.2018.06.236 |
0.478 |
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| 2006 |
Price BR, Sudduth TL, Dickey CA, Wilcock DM. P3-205: AN EMERGING ROLE FOR HSP27 IN VASCULAR COGNITIVE IMPAIRMENT AND DEMENTIA (VCID) Alzheimer's & Dementia. 14: P1146-P1146. DOI: 10.1016/j.jalz.2018.06.1564 |
0.57 |
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| 2006 |
Dickey CA, Petrucelli L, Hutton M, Eckman CB, Kamal A. P3-319: Manipulating components of the heat shock response as a therapeutic strategy for tauopathies Alzheimer's & Dementia. 2: S468-S469. DOI: 10.1016/J.Jalz.2006.05.1589 |
0.497 |
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| 2006 |
Petrucelli L, Dickey C, Dickson D, Hutton M, Patterson C, Caldwell G. P3-294: The impact of chip on neurodegenerative diseases Alzheimer's & Dementia. 2: S462-S462. DOI: 10.1016/J.Jalz.2006.05.1563 |
0.508 |
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| 2005 |
Lee WC, Courtenay A, Troendle FJ, Stallings-Mann ML, Dickey CA, DeLucia MW, Dickson DW, Eckman CB. Enzyme replacement therapy results in substantial improvements in early clinical phenotype in a mouse model of globoid cell leukodystrophy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1549-51. PMID 15987783 DOI: 10.1096/Fj.05-3826Fje |
0.341 |
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| 2005 |
Dickey CA, Eriksen J, Kamal A, Burrows F, Kasibhatla S, Eckman CB, Hutton M, Petrucelli L. Development of a high throughput drug screening assay for the detection of changes in tau levels -- proof of concept with HSP90 inhibitors. Current Alzheimer Research. 2: 231-8. PMID 15974923 DOI: 10.2174/1567205053585927 |
0.656 |
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| 2005 |
Dickey CA, Gordon MN, Wilcock DM, Herber DL, Freeman MJ, Morgan D. Dysregulation of Na+/K+ ATPase by amyloid in APP+PS1 transgenic mice. Bmc Neuroscience. 6: 7. PMID 15689237 DOI: 10.1186/1471-2202-6-7 |
0.736 |
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| 2004 |
Dickey CA, De Mesquita DD, Morgan D, Pennypacker KR. Induction of memory-associated immediate early genes by nerve growth factor in rat primary cortical neurons and differentiated mouse Neuro2A cells. Neuroscience Letters. 366: 10-4. PMID 15265580 DOI: 10.1016/J.Neulet.2004.04.089 |
0.562 |
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| 2004 |
Garcia MF, Gordon MN, Hutton M, Lewis J, McGowan E, Dickey CA, Morgan D, Arendash GW. The retinal degeneration (rd) gene seriously impairs spatial cognitive performance in normal and Alzheimer's transgenic mice. Neuroreport. 15: 73-7. PMID 15106834 DOI: 10.1097/00001756-200401190-00015 |
0.735 |
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| 2004 |
Dickey CA, Gordon MN, Mason JE, Wilson NJ, Diamond DM, Guzowski JF, Morgan D. Amyloid suppresses induction of genes critical for memory consolidation in APP + PS1 transgenic mice. Journal of Neurochemistry. 88: 434-42. PMID 14690531 DOI: 10.1111/J.1471-4159.2004.02185.X |
0.644 |
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| 2003 |
Dickey CA, Loring JF, Montgomery J, Gordon MN, Eastman PS, Morgan D. Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5219-26. PMID 12832546 DOI: 10.1523/Jneurosci.23-12-05219.2003 |
0.653 |
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| 2003 |
Austin L, Arendash GW, Gordon MN, Diamond DM, DiCarlo G, Dickey C, Ugen K, Morgan D. Short-term beta-amyloid vaccinations do not improve cognitive performance in cognitively impaired APP + PS1 mice. Behavioral Neuroscience. 117: 478-84. PMID 12802876 DOI: 10.1037/0735-7044.117.3.478 |
0.598 |
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| 2001 |
Wilcock DM, Gordon MN, Ugen KE, Gottschall PE, DiCarlo G, Dickey C, Boyett KW, Jantzen PT, Connor KE, Melachrino J, Hardy J, Morgan D. Number of Abeta inoculations in APP+PS1 transgenic mice influences antibody titers, microglial activation, and congophilic plaque levels. Dna and Cell Biology. 20: 731-6. PMID 11788051 DOI: 10.1089/10445490152717596 |
0.752 |
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| 2001 |
Dickey CA, Morgan DG, Kudchodkar S, Weiner DB, Bai Y, Cao C, Gordon MN, Ugen KE. Duration and specificity of humoral immune responses in mice vaccinated with the Alzheimer's disease-associated beta-amyloid 1-42 peptide. Dna and Cell Biology. 20: 723-9. PMID 11788050 DOI: 10.1089/10445490152717587 |
0.361 |
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| 2001 |
Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, Duff K, Jantzen P, DiCarlo G, Wilcock D, Connor K, Hatcher J, Hope C, Gordon M, Arendash GW. Erratum: correction: Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease Nature. 412: 660-660. DOI: 10.1038/35088102 |
0.729 |
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| 2000 |
Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, Duff K, Jantzen P, DiCarlo G, Wilcock D, Connor K, Hatcher J, Hope C, Gordon M, Arendash GW. A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease. Nature. 408: 982-5. PMID 11140686 DOI: 10.1038/35050116 |
0.731 |
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