Stefan Aigner, Ph.D. - Publications

Affiliations: 
University of Colorado, Boulder, Boulder, CO, United States 
Area:
RNA (ribozyme) catalysis

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Enustun E, Armbruster EG, Lee J, Zhang S, Yee BA, Gu Y, Deep A, Naritomi JT, Liang Q, Aigner S, Adler BA, Cress BF, Doudna JA, Chaikeeratisak V, Cleveland DW, et al. A phage nucleus-associated RNA-binding protein is required for jumbo phage infection. Biorxiv : the Preprint Server For Biology. PMID 37790334 DOI: 10.1101/2023.09.22.559000  0.487
2020 Okholm TLH, Sathe S, Park SS, Kamstrup AB, Rasmussen AM, Shankar A, Chua ZM, Fristrup N, Nielsen MM, Vang S, Dyrskjøt L, Aigner S, Damgaard CK, Yeo GW, Pedersen JS. Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression. Genome Medicine. 12: 112. PMID 33287884 DOI: 10.1186/s13073-020-00812-8  0.325
2020 Lasman L, Krupalnik V, Viukov S, Mor N, Aguilera-Castrejon A, Schneir D, Bayerl J, Mizrahi O, Peles S, Tawil S, Sathe S, Nachshon A, Shani T, Zerbib M, Kilimnik I, ... Aigner S, et al. Context-dependent functional compensation between Ythdf mA reader proteins. Genes & Development. PMID 32943573 DOI: 10.1101/Gad.340695.120  0.385
2020 Batra R, Nelles DA, Roth DM, Krach F, Nutter CA, Tadokoro T, Thomas JD, Sznajder ŁJ, Blue SM, Gutierrez HL, Liu P, Aigner S, Platoshyn O, Miyanohara A, Marsala M, et al. The sustained expression of Cas9 targeting toxic RNAs reverses disease phenotypes in mouse models of myotonic dystrophy type 1. Nature Biomedical Engineering. PMID 32929188 DOI: 10.1038/S41551-020-00607-7  0.423
2020 Tavares CDJ, Aigner S, Sharabi K, Sathe S, Mutlu B, Yeo GW, Puigserver P. Transcriptome-wide analysis of PGC-1α-binding RNAs identifies genes linked to glucagon metabolic action. Proceedings of the National Academy of Sciences of the United States of America. PMID 32848060 DOI: 10.1073/Pnas.2000643117  0.378
2020 Luo EC, Nathanson JL, Tan FE, Schwartz JL, Schmok JC, Shankar A, Markmiller S, Yee BA, Sathe S, Pratt GA, Scaletta DB, Ha Y, Hill DE, Aigner S, Yeo GW. Large-scale tethered function assays identify factors that regulate mRNA stability and translation. Nature Structural & Molecular Biology. PMID 32807991 DOI: 10.1038/S41594-020-0477-6  0.427
2020 Van Nostrand EL, Freese P, Pratt GA, Wang X, Wei X, Xiao R, Blue SM, Chen JY, Cody NAL, Dominguez D, Olson S, Sundararaman B, Zhan L, Bazile C, Bouvrette LPB, ... ... Aigner S, et al. A large-scale binding and functional map of human RNA-binding proteins. Nature. 583: 711-719. PMID 32728246 DOI: 10.1038/S41586-020-2077-3  0.427
2020 Coyne AN, Zaepfel BL, Hayes L, Fitchman B, Salzberg Y, Luo EC, Bowen K, Trost H, Aigner S, Rigo F, Yeo GW, Harel A, Svendsen CN, Sareen D, Rothstein JD. GC Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD. Neuron. PMID 32673563 DOI: 10.1016/J.Neuron.2020.06.027  0.395
2020 Donsbach P, Yee BA, Sanchez-Hevia D, Berenguer J, Aigner S, Yeo GW, Klostermeier D. The Thermus thermophilus DEAD-box protein Hera is a general RNA binding protein and plays a key role in tRNA metabolism. Rna (New York, N.Y.). PMID 32669294 DOI: 10.1261/Rna.075580.120  0.435
2019 Di Stefano B, Luo EC, Haggerty C, Aigner S, Charlton J, Brumbaugh J, Ji F, Rabano Jiménez I, Clowers KJ, Huebner AJ, Clement K, Lipchina I, de Kort MAC, Anselmo A, Pulice J, et al. The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis. Cell Stem Cell. PMID 31588046 DOI: 10.1016/J.Stem.2019.08.018  0.419
2017 Kathuria A, Nowosiad P, Jagasia R, Aigner S, Taylor RD, Andreae LC, Gatford NJF, Lucchesi W, Srivastava DP, Price J. Stem cell-derived neurons from autistic individuals with SHANK3 mutation show morphogenetic abnormalities during early development. Molecular Psychiatry. PMID 28948968 DOI: 10.1038/Mp.2017.185  0.323
2017 Gündner AL, Meyer CA, Aigner S, Christensen K, Patsch C, Jagasia R, Baumann K, Burcin M. Generation of a homozygous GBA deletion human embryonic stem cell line. Stem Cell Research. 23: 122-126. PMID 28925361 DOI: 10.1016/J.Scr.2017.07.009  0.317
2017 Batra R, Nelles DA, Pirie E, Blue SM, Marina RJ, Wang H, Chaim IA, Thomas JD, Zhang N, Nguyen V, Aigner S, Markmiller S, Xia G, Corbett KD, Swanson MS, et al. Elimination of Toxic Microsatellite Repeat Expansion RNA by RNA-Targeting Cas9. Cell. PMID 28803727 DOI: 10.1016/J.Cell.2017.07.010  0.422
2017 Kakaradov B, Arsenio J, Widjaja CE, He Z, Aigner S, Metz PJ, Yu B, Wehrens EJ, Lopez J, Kim SH, Zuniga EI, Goldrath AW, Chang JT, Yeo GW. Early transcriptional and epigenetic regulation of CD8(+) T cell differentiation revealed by single-cell RNA sequencing. Nature Immunology. PMID 28218746 DOI: 10.1038/Ni.3688  0.342
2016 Batra R, Stark TJ, Clark E, Belzile JP, Wheeler EC, Yee BA, Huang H, Gelboin-Burkhart C, Huelga SC, Aigner S, Roberts BT, Bos TJ, Sathe S, Donohue JP, Rigo F, et al. RNA-binding protein CPEB1 remodels host and viral RNA landscapes. Nature Structural & Molecular Biology. PMID 27775709 DOI: 10.1038/Nsmb.3310  0.372
2016 Bos TJ, Nussbacher JK, Aigner S, Yeo GW. Tethered Function Assays as Tools to Elucidate the Molecular Roles of RNA-Binding Proteins. Advances in Experimental Medicine and Biology. 907: 61-88. PMID 27256382 DOI: 10.1007/978-3-319-29073-7_3  0.442
2016 Conway AE, Van Nostrand EL, Pratt GA, Aigner S, Wilbert ML, Sundararaman B, Freese P, Lambert NJ, Sathe S, Liang TY, Essex A, Landais S, Burge CB, Jones DL, Yeo GW. Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival. Cell Reports. PMID 27068461 DOI: 10.1016/J.Celrep.2016.03.052  0.439
2016 Costa V, Aigner S, Vukcevic M, Sauter E, Behr K, Ebeling M, Dunkley T, Friedlein A, Zoffmann S, Meyer CA, Knoflach F, Lugert S, Patsch C, Fjeldskaar F, Chicha-Gaudimier L, et al. mTORC1 Inhibition Corrects Neurodevelopmental and Synaptic Alterations in a Human Stem Cell Model of Tuberous Sclerosis. Cell Reports. 15: 86-95. PMID 27052171 DOI: 10.1016/J.Celrep.2016.02.090  0.302
2015 Nelles DA, Fang MY, Aigner S, Yeo GW. Applications of Cas9 as an RNA-programmed RNA-binding protein. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 37: 732-9. PMID 25880497 DOI: 10.1002/Bies.201500001  0.433
2015 Dunkley T, Costa V, Friedlein A, Lugert S, Aigner S, Ebeling M, Miller MT, Patsch C, Piraino P, Cutler P, Jagasia R. Characterization of a human pluripotent stem cell-derived model of neuronal development using multiplexed targeted proteomics. Proteomics. Clinical Applications. 9: 684-94. PMID 25684324 DOI: 10.1002/Prca.201400150  0.357
2014 Havlicek S, Kohl Z, Mishra HK, Prots I, Eberhardt E, Denguir N, Wend H, Plötz S, Boyer L, Marchetto MC, Aigner S, Sticht H, Groemer TW, Hehr U, Lampert A, et al. Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons. Human Molecular Genetics. 23: 2527-41. PMID 24381312 DOI: 10.1093/Hmg/Ddt644  0.314
2014 Aigner S, Heckel T, Zhang JD, Andreae LC, Jagasia R. Human pluripotent stem cell models of autism spectrum disorder: emerging frontiers, opportunities, and challenges towards neuronal networks in a dish. Psychopharmacology. 231: 1089-104. PMID 24232378 DOI: 10.1007/S00213-013-3332-1  0.303
2008 Jessberger S, Aigner S, Clemenson GD, Toni N, Lie DC, Karalay O, Overall R, Kempermann G, Gage FH. Cdk5 regulates accurate maturation of newborn granule cells in the adult hippocampus. Plos Biology. 6: e272. PMID 18998770 DOI: 10.1371/Journal.Pbio.0060272  0.304
2008 Yeo GW, Coufal N, Aigner S, Winner B, Scolnick JA, Marchetto MC, Muotri AR, Carson C, Gage FH. Multiple layers of molecular controls modulate self-renewal and neuronal lineage specification of embryonic stem cells. Human Molecular Genetics. 17: R67-75. PMID 18632700 DOI: 10.1093/Hmg/Ddn065  0.346
2007 Aigner S, Denli AM, Gage FH. A novel model for an older remodeler: the BAF swap in neurogenesis. Neuron. 55: 171-3. PMID 17640518 DOI: 10.1016/J.Neuron.2007.07.004  0.302
2005 Aigner S, Gage FH. A small gem with great powers: geminin keeps neural progenitors thriving. Developmental Cell. 9: 171-2. PMID 16054024 DOI: 10.1016/J.Devcel.2005.07.005  0.31
2004 Aigner S, Cech TR. The Euplotes telomerase subunit p43 stimulates enzymatic activity and processivity in vitro. Rna (New York, N.Y.). 10: 1108-18. PMID 15208446 DOI: 10.1261/Rna.7400704  0.552
2003 Aigner S, Postberg J, Lipps HJ, Cech TR. The Euplotes La motif protein p43 has properties of a telomerase-specific subunit. Biochemistry. 42: 5736-47. PMID 12741831 DOI: 10.1021/Bi034121Y  0.586
2000 Seiwert SD, Stines Nahreini T, Aigner S, Ahn NG, Uhlenbeck OC. RNA aptamers as pathway-specific MAP kinase inhibitors. Chemistry & Biology. 7: 833-43. PMID 11094337 DOI: 10.1016/S1074-5521(00)00032-6  0.329
2000 Aigner S, Lingner J, Goodrich KJ, Grosshans CA, Shevchenko A, Mann M, Cech TR. Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting. The Embo Journal. 19: 6230-9. PMID 11080168 DOI: 10.1093/Emboj/19.22.6230  0.645
1997 Jabri E, Aigner S, Cech TR. Kinetic and secondary structure analysis of Naegleria andersoni GIR1, a group I ribozyme whose putative biological function is site-specific hydrolysis. Biochemistry. 36: 16345-54. PMID 9405070 DOI: 10.1021/Bi9718595  0.474
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