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Garth A. Kinberger, Ph.D. - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
peptides
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17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Nikan M, Li W, Kinberger GA, Seth PP, Swayze EE, Prakash TP. -Acyl-2-Thioethyl: A Convenient Base-Labile Protecting Group for the Synthesis of siRNAs Containing 5'-Vinylphosphonate. Molecules (Basel, Switzerland). 24. PMID 30634486 DOI: 10.3390/Molecules24020225  0.35
2018 Prakash TP, Yu J, Kinberger GA, Low A, Jackson M, Rigo F, Swayze EE, Seth PP. Evaluation of the effect of 2'-O-methyl, fluoro hexitol, bicyclo and Morpholino nucleic acid modifications on potency of GalNAc conjugated antisense oligonucleotides in mice. Bioorganic & Medicinal Chemistry Letters. PMID 30342955 DOI: 10.1016/J.Bmcl.2018.10.011  0.331
2017 Schmidt K, Prakash TP, Donner AJ, Kinberger GA, Gaus HJ, Low A, Østergaard ME, Bell M, Swayze EE, Seth PP. Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor. Nucleic Acids Research. PMID 28158620 DOI: 10.1093/Nar/Gkx060  0.337
2016 Schirle NT, Kinberger GA, Murray HF, Lima WF, Prakash TP, MacRae IJ. Structural analysis of human Argonaute-2 bound to a modified siRNA guide. Journal of the American Chemical Society. PMID 27380263 DOI: 10.1021/Jacs.6B04454  0.376
2016 Kinberger GA, Prakash TP, Yu J, Vasquez G, Low A, Chappell A, Schmidt K, Murray HM, Gaus H, Swayze EE, Seth PP. Conjugation of mono and di-GalNAc sugars enhances the potency of antisense oligonucleotides via ASGR mediated delivery to hepatocytes. Bioorganic & Medicinal Chemistry Letters. PMID 27268307 DOI: 10.1016/J.Bmcl.2016.05.084  0.331
2016 Prakash TP, Kinberger GA, Murray HM, Chappell A, Riney S, Graham MJ, Lima WF, Swayze EE, Seth PP. Synergistic effect of phosphorothioate, 5'-vinylphosphonate and GalNAc modifications for enhancing activity of synthetic siRNA. Bioorganic & Medicinal Chemistry Letters. PMID 27161280 DOI: 10.1016/J.Bmcl.2016.04.063  0.372
2016 Migawa MT, Prakash TP, Vasquez G, Wan WB, Yu J, Kinberger GA, Østergaard ME, Swayze EE, Seth PP. A convenient synthesis of 5'-triantennary N-acetyl-galactosamine clusters based on nitromethanetrispropionic acid. Bioorganic & Medicinal Chemistry Letters. PMID 27025342 DOI: 10.1016/J.Bmcl.2016.03.070  0.372
2016 Prakash TP, Yu J, Migawa MT, Kinberger GA, Wan WB, Østergaard ME, Carty RL, Vasquez G, Low A, Chappell A, Schmidt K, Aghajan M, Crosby J, Murray HM, Booten SL, et al. Comprehensive Structure Activity Relationship of Triantennary N-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes. Journal of Medicinal Chemistry. PMID 26914862 DOI: 10.1021/Acs.Jmedchem.5B01948  0.423
2015 Prakash TP, Brad Wan W, Low A, Yu J, Chappell AE, Gaus H, Kinberger GA, Østergaard ME, Migawa MT, Swayze EE, Seth PP. Solid-phase synthesis of 5'-triantennary N-acetylgalactosamine conjugated antisense oligonucleotides using phosphoramidite chemistry. Bioorganic & Medicinal Chemistry Letters. PMID 26299345 DOI: 10.1016/j.bmcl.2015.08.019  0.315
2010 Seth PP, Vasquez G, Allerson CA, Berdeja A, Gaus H, Kinberger GA, Prakash TP, Migawa MT, Bhat B, Swayze EE. Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analogues. The Journal of Organic Chemistry. 75: 1569-81. PMID 20136157 DOI: 10.1021/Jo902560F  0.372
2007 Cai W, Wong D, Kinberger GA, Kwok SW, Taulane JP, Goodman M. Facile and efficient assembly of collagen-like triple helices on a TRIS scaffold. Bioorganic Chemistry. 35: 327-37. PMID 17368718 DOI: 10.1016/J.Bioorg.2007.01.003  0.571
2006 Maier MA, Esau CC, Siwkowski AM, Wancewicz EV, Albertshofer K, Kinberger GA, Kadaba NS, Watanabe T, Manoharan M, Bennett CF, Griffey RH, Swayze EE. Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acids. Journal of Medicinal Chemistry. 49: 2534-42. PMID 16610796 DOI: 10.1021/jm051275y  0.314
2006 Kinberger GA, Taulane JP, Goodman M. Fe(III)-binding collagen mimetics. Inorganic Chemistry. 45: 961-3. PMID 16441100 DOI: 10.1021/Ic0520059  0.521
2006 Kinberger GA, Taulane JP, Goodman M. The design, synthesis, and characterization of a PAMAM-based triple helical collagen mimetic dendrimer Tetrahedron. 62: 5280-5286. DOI: 10.1016/J.Tet.2006.01.107  0.523
2005 Albertshofer K, Siwkowski AM, Wancewicz EV, Esau CC, Watanabe T, Nishihara KC, Kinberger GA, Malik L, Eldrup AB, Manoharan M, Geary RS, Monia BP, Swayze EE, Griffey RH, Bennett CF, et al. Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid. Journal of Medicinal Chemistry. 48: 6741-9. PMID 16220989 DOI: 10.1021/jm050490b  0.307
2003 Goodman M, Cai W, Kinberger GA. The New Science of Protein Mimetics Macromolecular Symposia. 201: 223-236. DOI: 10.1002/Masy.200351125  0.611
2002 Kinberger GA, Cai W, Goodman M. Collagen mimetic dendrimers. Journal of the American Chemical Society. 124: 15162-3. PMID 12487577 DOI: 10.1021/Ja021203L  0.604
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