| Year |
Citation |
Score |
| 2023 |
Vilbois S, Xu Y, Ho PC. Metabolic interplay: tumor macrophages and regulatory T cells. Trends in Cancer. PMID 38135571 DOI: 10.1016/j.trecan.2023.11.007 |
0.342 |
|
| 2023 |
Park J, Hsueh PC, Li Z, Ho PC. Microenvironment-driven metabolic adaptations guiding CD8 T cell anti-tumor immunity. Immunity. 56: 32-42. PMID 36630916 DOI: 10.1016/j.immuni.2022.12.008 |
0.301 |
|
| 2022 |
Raines LN, Zhao H, Wang Y, Chen HY, Gallart-Ayala H, Hsueh PC, Cao W, Koh Y, Alamonte-Loya A, Liu PS, Ivanisevic J, Lio CJ, Ho PC, Huang SC. PERK is a critical metabolic hub for immunosuppressive function in macrophages. Nature Immunology. 23: 431-445. PMID 35228694 DOI: 10.1038/s41590-022-01145-x |
0.356 |
|
| 2021 |
Guo Y, Xie YQ, Gao M, Zhao Y, Franco F, Wenes M, Siddiqui I, Bevilacqua A, Wang H, Yang H, Feng B, Xie X, Sabatel CM, Tschumi B, Chaiboonchoe A, ... ... Ho PC, et al. Metabolic reprogramming of terminally exhausted CD8 T cells by IL-10 enhances anti-tumor immunity. Nature Immunology. PMID 34031618 DOI: 10.1038/s41590-021-00940-2 |
0.318 |
|
| 2021 |
Zappasodi R, Serganova I, Cohen IJ, Maeda M, Shindo M, Senbabaoglu Y, Watson MJ, Leftin A, Maniyar R, Verma S, Lubin M, Ko M, Mane MM, Zhong H, Liu C, ... ... Ho PC, et al. CTLA-4 blockade drives loss of T stability in glycolysis-low tumours. Nature. PMID 33588426 DOI: 10.1038/s41586-021-03326-4 |
0.307 |
|
| 2021 |
Xin G, Chen Y, Topchyan P, Kasmani MY, Burns R, Volberding PJ, Wu X, Cohn A, Chen Y, Lin CW, Ho PC, Silverstein R, Dwinell M, Cui W. Targeting PIM1-Mediated Metabolism in Myeloid Suppressor Cells to Treat Cancer. Cancer Immunology Research. PMID 33579728 DOI: 10.1158/2326-6066.CIR-20-0433 |
0.332 |
|
| 2020 |
Franco F, Jaccard A, Romero P, Yu YR, Ho PC. Metabolic and epigenetic regulation of T-cell exhaustion. Nature Metabolism. PMID 32958939 DOI: 10.1038/s42255-020-00280-9 |
0.301 |
|
| 2020 |
Rath JA, Bajwa G, Carreres B, Hoyer E, Gruber I, Martínez-Paniagua MA, Yu YR, Nouraee N, Sadeghi F, Wu M, Wang T, Hebeisen M, Rufer N, Varadarajan N, Ho PC, et al. Single-cell transcriptomics identifies multiple pathways underlying antitumor function of TCR- and CD8αβ-engineered human CD4 T cells. Science Advances. 6: eaaz7809. PMID 32923584 DOI: 10.1126/Sciadv.Aaz7809 |
0.37 |
|
| 2020 |
Di Conza G, Ho PC. ER Stress Responses: An Emerging Modulator for Innate Immunity. Cells. 9. PMID 32178254 DOI: 10.3390/Cells9030695 |
0.334 |
|
| 2020 |
Wang H, Lu CH, Ho PC. Metabolic adaptation orchestrates tissue context-dependent behavior in regulatory T cells. Immunological Reviews. PMID 32147869 DOI: 10.1111/Imr.12844 |
0.398 |
|
| 2020 |
Wang H, Franco F, Tsui YC, Xie X, Trefny MP, Zappasodi R, Mohmood SR, Fernández-García J, Tsai CH, Schulze I, Picard F, Meylan E, Silverstein R, Goldberg I, Fendt SM, ... ... Ho PC, et al. CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors. Nature Immunology. PMID 32066953 DOI: 10.1038/S41590-019-0589-5 |
0.418 |
|
| 2020 |
Dumauthioz N, Tschumi B, Wenes M, Marti B, Wang H, Franco F, Li W, Lopez-Mejia IC, Fajas L, Ho PC, Donda A, Romero P, Zhang L. Enforced PGC-1α expression promotes CD8 T cell fitness, memory formation and antitumor immunity. Cellular & Molecular Immunology. PMID 32055005 DOI: 10.1038/S41423-020-0365-3 |
0.375 |
|
| 2020 |
Monnot GC, Martinez-Usatorre A, Lanitis E, Lopes SF, Cheng WC, Ho PC, Irving M, Coukos G, Donda A, Romero P. miR-155 Overexpression in OT-1 CD8 T Cells Improves Anti-Tumor Activity against Low-Affinity Tumor Antigen. Molecular Therapy Oncolytics. 16: 111-123. PMID 32021906 DOI: 10.1016/J.Omto.2019.12.008 |
0.337 |
|
| 2020 |
Zappasodi R, Serganova I, Cohen I, Maeda M, Shindo M, Senbabaoglu Y, Leftin A, Maniyar R, Verma S, Lubin M, Ko MK, Mane MM, Ghosh A, Ackerstaff E, Koutcher JA, ... Ho P, et al. Abstract 3257: CTLA-4 blockade drives loss of regulatory T cell functional stability in glycolysis defective tumors Immunology. 80: 3257-3257. DOI: 10.1158/1538-7445.Am2020-3257 |
0.424 |
|
| 2019 |
Salomé B, Gomez-Cadena A, Loyon R, Suffiotti M, Salvestrini V, Wyss T, Vanoni G, Ruan DF, Rossi M, Tozzo A, Tentorio P, Bruni E, Riether C, Jacobsen EM, Jandus P, ... ... Ho PC, et al. CD56 as a marker of an ILC1-like population with NK cell properties that is functionally impaired in AML. Blood Advances. 3: 3674-3687. PMID 31765481 DOI: 10.1182/Bloodadvances.2018030478 |
0.337 |
|
| 2019 |
Mastelic-Gavillet B, Navarro Rodrigo B, Décombaz L, Wang H, Ercolano G, Ahmed R, Lozano LE, Ianaro A, Derré L, Valerio M, Tawadros T, Jichlinski P, Nguyen-Ngoc T, Speiser DE, Verdeil G, ... ... Ho PC, et al. Adenosine mediates functional and metabolic suppression of peripheral and tumor-infiltrating CD8 T cells. Journal For Immunotherapy of Cancer. 7: 257. PMID 31601268 DOI: 10.1186/S40425-019-0719-5 |
0.381 |
|
| 2019 |
Di Conza G, Tsai CH, Ho PC. Fifty Shades of α-Ketoglutarate on Cellular Programming. Molecular Cell. 76: 1-3. PMID 31585100 DOI: 10.1016/J.Molcel.2019.09.002 |
0.377 |
|
| 2019 |
Cheng WC, Ho PC. Firing Up Cold Tumors. Trends in Cancer. 5: 528-530. PMID 31474357 DOI: 10.1016/J.Trecan.2019.06.005 |
0.342 |
|
| 2019 |
Riera-Domingo C, Audigé A, Granja S, Cheng WC, Ho PC, Baltazar F, Stockmann C, Mazzone M. Immunity, Hypoxia and Metabolism - the ménage à trois of cancer: implications for immunotherapy. Physiological Reviews. PMID 31414610 DOI: 10.1152/Physrev.00018.2019 |
0.362 |
|
| 2019 |
Ayeni D, Miller B, Kuhlmann A, Ho PC, Robles-Oteiza C, Gaefele M, Levy S, de Miguel FJ, Perry C, Guan T, Krystal G, Lockwood W, Zelterman D, Homer R, Liu Z, et al. Tumor regression mediated by oncogene withdrawal or erlotinib stimulates infiltration of inflammatory immune cells in EGFR mutant lung tumors. Journal For Immunotherapy of Cancer. 7: 172. PMID 31291990 DOI: 10.1186/S40425-019-0643-8 |
0.32 |
|
| 2019 |
Niogret C, Miah SMS, Rota G, Fonta NP, Wang H, Held W, Birchmeier W, Sexl V, Yang W, Vivier E, Ho PC, Brossay L, Guarda G. Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells. Nature Communications. 10: 1444. PMID 30926899 DOI: 10.1038/S41467-019-09431-3 |
0.316 |
|
| 2019 |
Li X, Wenes M, Romero P, Huang SC, Fendt SM, Ho PC. Navigating metabolic pathways to enhance antitumour immunity and immunotherapy. Nature Reviews. Clinical Oncology. PMID 30914826 DOI: 10.1038/S41571-019-0203-7 |
0.402 |
|
| 2019 |
Cheng WC, Tsui YC, Ragusa S, Koelzer VH, Mina M, Franco F, Läubli H, Tschumi B, Speiser D, Romero P, Zippelius A, Petrova TV, Mertz K, Ciriello G, Ho PC. Uncoupling protein 2 reprograms the tumor microenvironment to support the anti-tumor immune cycle. Nature Immunology. 20: 206-217. PMID 30664764 DOI: 10.1038/S41590-018-0290-0 |
0.386 |
|
| 2019 |
Liu PS, Ho PC. Determining Macrophage Polarization upon Metabolic Perturbation. Methods in Molecular Biology (Clifton, N.J.). 1862: 173-186. PMID 30315468 DOI: 10.1007/978-1-4939-8769-6_13 |
0.342 |
|
| 2019 |
Rath JA, Bajwa G, Carreres B, Gruber I, Hoyer E, Wu M, Yu Y, Ho P, Brenner MK, Gfeller D, Arber C. Single Cell RNA Sequencing Identifies Transcriptional Programs That Enhance Anti-Tumor Function of Transgenic CD4+ T Cells Redirected with TCR and CD8αβ Blood. 134: 250-250. DOI: 10.1182/Blood-2019-124714 |
0.335 |
|
| 2019 |
Wang H, Ho P. Abstract A223: CD36-mediated metabolic adaptation guides regulatory T-cells in tumors Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A223 |
0.378 |
|
| 2018 |
Franco F, Wenes M, Ho PC. Sparks Fly in PGE2-Modulated Macrophage Polarization. Immunity. 49: 987-989. PMID 30566885 DOI: 10.1016/J.Immuni.2018.12.002 |
0.357 |
|
| 2018 |
Castro W, Chelbi ST, Niogret C, Ramon-Barros C, Welten SPM, Osterheld K, Wang H, Rota G, Morgado L, Vivier E, Raeber ME, Boyman O, Delorenzi M, Barras D, Ho PC, et al. The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity. Nature Immunology. PMID 29967452 DOI: 10.1038/S41590-018-0144-9 |
0.407 |
|
| 2018 |
Di Conza G, Ho PC. Metabolic adaptation of macrophages in chronic diseases. Cancer Letters. 414: 250-256. PMID 29175462 DOI: 10.1016/J.Canlet.2017.11.023 |
0.364 |
|
| 2018 |
Vannini N, Campos V, Girotra M, Rojas-Sutterlin S, Tratwal J, Ragusa S, Stefanidis E, Ryu D, Rainer PY, Nikitin G, Giger S, Li Terytty Y, Semilietof A, Oggier AL, Yersin Y, ... ... Ho P, et al. The NAD+ Salvage Pathway Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance and Asymmetric Division Blood. 132: 641-641. DOI: 10.1182/Blood-2018-99-117388 |
0.309 |
|
| 2017 |
Liu PS, Ho PC. Mitochondria: A master regulator in macrophage and T cell immunity. Mitochondrion. PMID 29146487 DOI: 10.1016/J.Mito.2017.11.002 |
0.409 |
|
| 2017 |
Ho PC, Hess C. Editorial: Immunometabolic Regulations in Adaptive and Innate Immune Cells Shapes and Re-Directs Host Immunity. Frontiers in Immunology. 8: 852. PMID 28791013 DOI: 10.3389/Fimmu.2017.00852 |
0.309 |
|
| 2017 |
Wang H, Franco F, Ho PC. Metabolic Regulation of Tregs in Cancer: Opportunities for Immunotherapy. Trends in Cancer. 3: 583-592. PMID 28780935 DOI: 10.1016/J.Trecan.2017.06.005 |
0.379 |
|
| 2017 |
Liu PS, Wang H, Li X, Chao T, Teav T, Christen S, Di Conza G, Cheng WC, Chou CH, Vavakova M, Muret C, Debackere K, Mazzone M, Huang HD, Fendt SM, ... ... Ho PC, et al. α-ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming. Nature Immunology. PMID 28714978 DOI: 10.1038/Ni.3796 |
0.359 |
|
| 2017 |
Chao T, Wang H, Ho PC. Mitochondrial Control and Guidance of Cellular Activities of T Cells. Frontiers in Immunology. 8: 473. PMID 28484465 DOI: 10.3389/Fimmu.2017.00473 |
0.43 |
|
| 2017 |
Ho PC, Kaech SM. Reenergizing T cell anti-tumor immunity by harnessing immunometabolic checkpoints and machineries. Current Opinion in Immunology. 46: 38-44. PMID 28458087 DOI: 10.1016/J.Coi.2017.04.003 |
0.417 |
|
| 2016 |
Coutaz M, Hurrell BP, Auderset F, Wang H, Siegert S, Eberl G, Ho PC, Radtke F, Tacchini-Cottier F. Notch regulates Th17 differentiation and controls trafficking of IL-17 and metabolic regulators within Th17 cells in a context-dependent manner. Scientific Reports. 6: 39117. PMID 27974744 DOI: 10.1038/Srep39117 |
0.387 |
|
| 2016 |
Speiser DE, Ho PC, Verdeil G. Regulatory circuits of T cell function in cancer. Nature Reviews. Immunology. PMID 27526640 DOI: 10.1038/Nri.2016.80 |
0.352 |
|
| 2016 |
Cheng WC, Ho PC. Metabolic tug-of-war in tumors results in diminished T cell antitumor immunity. Oncoimmunology. 5: e1119355. PMID 27141402 DOI: 10.1080/2162402X.2015.1119355 |
0.388 |
|
| 2016 |
Ho PC, Liu PS. Metabolic communication in tumors: a new layer of immunoregulation for immune evasion. Journal For Immunotherapy of Cancer. 4: 4. PMID 26885366 DOI: 10.1186/S40425-016-0109-1 |
0.376 |
|
| 2016 |
Cui G, Ho P, Amezquita R, Kaech SM. Abstract IA03: Anti-tumor T cells: You are what you eat Cancer Immunology Research. 5. DOI: 10.1158/2326-6074.Tumimm16-Ia03 |
0.406 |
|
| 2016 |
Ayeni D, Ho P, Perry C, Kaech S, Politi K. Abstract A083: Modulation of the immune system as a strategy to treat EGFR mutant lung adenocarcinoma Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A083 |
0.344 |
|
| 2015 |
Ray JP, Staron MM, Shyer JA, Ho PC, Marshall HD, Gray SM, Laidlaw BJ, Araki K, Ahmed R, Kaech SM, Craft J. The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. Immunity. PMID 26410627 DOI: 10.1016/J.Immuni.2015.08.017 |
0.42 |
|
| 2015 |
Ho PC, Bihuniak JD, Macintyre AN, Staron M, Liu X, Amezquita R, Tsui YC, Cui G, Micevic G, Perales JC, Kleinstein SH, Abel ED, Insogna KL, Feske S, Locasale JW, et al. Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses. Cell. PMID 26321681 DOI: 10.1016/J.Cell.2015.08.012 |
0.302 |
|
| 2015 |
Cui G, Staron MM, Gray SM, Ho PC, Amezquita RA, Wu J, Kaech SM. IL-7-Induced Glycerol Transport and TAG Synthesis Promotes Memory CD8+ T Cell Longevity. Cell. 161: 750-61. PMID 25957683 DOI: 10.1016/J.Cell.2015.03.021 |
0.319 |
|
| 2015 |
Feng M, Chen JY, Weissman-Tsukamoto R, Volkmer JP, Ho PY, McKenna KM, Cheshier S, Zhang M, Guo N, Gip P, Mitra SS, Weissman IL. Macrophages eat cancer cells using their own calreticulin as a guide: roles of TLR and Btk. Proceedings of the National Academy of Sciences of the United States of America. 112: 2145-50. PMID 25646432 DOI: 10.1073/Pnas.1424907112 |
0.303 |
|
| 2014 |
Ho PC, Kaech SM. BRAF-targeted therapy alters the functions of intratumoral CD4(+) T cells to inhibit melanoma progression. Oncoimmunology. 3: e29126. PMID 25083331 DOI: 10.4161/Onci.29126 |
0.382 |
|
| 2014 |
Ho PC, Meeth KM, Tsui YC, Srivastava B, Bosenberg MW, Kaech SM. Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ. Cancer Research. 74: 3205-17. PMID 24736544 DOI: 10.1158/0008-5472.Can-13-3461 |
0.374 |
|
| 2012 |
Ho PC, Wei LN. Biological activities of receptor-interacting protein 140 in adipocytes and metabolic diseases. Current Diabetes Reviews. 8: 452-7. PMID 22934550 DOI: 10.2174/157339912803529922 |
0.488 |
|
| 2012 |
Ho PC, Tsui YC, Feng X, Greaves DR, Wei LN. NF-κB-mediated degradation of the coactivator RIP140 regulates inflammatory responses and contributes to endotoxin tolerance. Nature Immunology. 13: 379-86. PMID 22388040 DOI: 10.1038/Ni.2238 |
0.455 |
|
| 2012 |
Ho PC, Tsui YC, Lin YW, Persaud SD, Wei LN. Endothelin-1 promotes cytoplasmic accumulation of RIP140 through a ET(A)-PLCβ-PKCε pathway. Molecular and Cellular Endocrinology. 351: 176-83. PMID 22209746 DOI: 10.1016/j.mce.2011.12.003 |
0.461 |
|
| 2012 |
Ho PC, Wei LN. Negative regulation of adiponectin secretion by receptor interacting protein 140 (RIP140). Cellular Signalling. 24: 71-6. PMID 21872658 DOI: 10.1016/J.Cellsig.2011.07.018 |
0.516 |
|
| 2011 |
Ho PC, Chuang YS, Hung CH, Wei LN. Cytoplasmic receptor-interacting protein 140 (RIP140) interacts with perilipin to regulate lipolysis. Cellular Signalling. 23: 1396-403. PMID 21504789 DOI: 10.1016/j.cellsig.2011.03.023 |
0.486 |
|
| 2011 |
Chuang YS, Huang WH, Park SW, Persaud SD, Hung CH, Ho PC, Wei LN. Promyelocytic leukemia protein in retinoic acid-induced chromatin remodeling of Oct4 gene promoter. Stem Cells (Dayton, Ohio). 29: 660-9. PMID 21360626 DOI: 10.1002/Stem.623 |
0.449 |
|
| 2011 |
Ho PC, Chang KC, Chuang YS, Wei LN. Cholesterol regulation of receptor-interacting protein 140 via microRNA-33 in inflammatory cytokine production. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1758-66. PMID 21285396 DOI: 10.1096/fj.10-179267 |
0.416 |
|
| 2009 |
Ho PC, Lin YW, Tsui YC, Gupta P, Wei LN. A negative regulatory pathway of GLUT4 trafficking in adipocyte: new function of RIP140 in the cytoplasm via AS160. Cell Metabolism. 10: 516-23. PMID 19945409 DOI: 10.1016/j.cmet.2009.09.012 |
0.45 |
|
| 2009 |
Gupta P, Ho PC, Ha SG, Lin YW, Wei LN. HDAC3 as a molecular chaperone for shuttling phosphorylated TR2 to PML: a novel deacetylase activity-independent function of HDAC3. Plos One. 4: e4363. PMID 19204783 DOI: 10.1371/journal.pone.0004363 |
0.45 |
|
| 2008 |
Gupta P, Ho PC, Huq MM, Ha SG, Park SW, Khan AA, Tsai NP, Wei LN. Retinoic acid-stimulated sequential phosphorylation, PML recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 expression. Proceedings of the National Academy of Sciences of the United States of America. 105: 11424-9. PMID 18682553 DOI: 10.1073/Pnas.0710561105 |
0.653 |
|
| 2008 |
Ho PC, Gupta P, Tsui YC, Ha SG, Huq M, Wei LN. Modulation of lysine acetylation-stimulated repressive activity by Erk2-mediated phosphorylation of RIP140 in adipocyte differentiation. Cellular Signalling. 20: 1911-9. PMID 18655826 DOI: 10.1016/J.Cellsig.2008.07.001 |
0.497 |
|
| 2008 |
Gupta P, Ho PC, Huq MD, Khan AA, Tsai NP, Wei LN. PKCepsilon stimulated arginine methylation of RIP140 for its nuclear-cytoplasmic export in adipocyte differentiation. Plos One. 3: e2658. PMID 18628823 DOI: 10.1371/journal.pone.0002658 |
0.613 |
|
| 2008 |
Tsai NP, Ho PC, Wei LN. Regulation of stress granule dynamics by Grb7 and FAK signalling pathway. The Embo Journal. 27: 715-26. PMID 18273060 DOI: 10.1038/emboj.2008.19 |
0.628 |
|
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