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Justin T. Ernst, Ph.D. - Publications

Affiliations: 
2002 Yale University, New Haven, CT 
Area:
chemical biology
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10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Montalban AG, Boman E, Chang CD, Ceide SC, Dahl R, Dalesandro D, Delaet NG, Erb E, Ernst JT, Gibbs A, Kahl J, Kessler L, Kucharski J, Lum C, Lundström J, et al. Optimization of alpha-ketoamide based p38 inhibitors through modifications to the region that binds to the allosteric site. Bioorganic & Medicinal Chemistry Letters. 20: 4819-24. PMID 20663667 DOI: 10.1016/J.Bmcl.2010.06.102  0.404
2010 Montalban AG, Boman E, Chang CD, Ceide SC, Dahl R, Dalesandro D, Delaet NG, Erb E, Ernst J, Gibbs A, Kahl J, Kessler L, Lundström J, Miller S, Nakanishi H, et al. KR-003048, a potent, orally active inhibitor of p38 mitogen-activated protein kinase. European Journal of Pharmacology. 632: 93-102. PMID 20132813 DOI: 10.1016/J.Ejphar.2010.01.011  0.303
2008 Montalban AG, Boman E, Chang CD, Ceide SC, Dahl R, Dalesandro D, Delaet NG, Erb E, Ernst JT, Gibbs A, Kahl J, Kessler L, Lundström J, Miller S, Nakanishi H, et al. The design and synthesis of novel alpha-ketoamide-based p38 MAP kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 1772-7. PMID 18325768 DOI: 10.1016/J.Bmcl.2008.02.033  0.301
2005 Yin H, Lee GI, Sedey KA, Kutzki O, Park HS, Orner BP, Ernst JT, Wang HG, Sebti SM, Hamilton AD. Terphenyl-Based Bak BH3 alpha-helical proteomimetics as low-molecular-weight antagonists of Bcl-xL. Journal of the American Chemical Society. 127: 10191-6. PMID 16028929 DOI: 10.1021/Ja050122X  0.679
2004 Jain R, Ernst JT, Kutzki O, Park HS, Hamilton AD. Protein recognition using synthetic surface-targeted agents. Molecular Diversity. 8: 89-100. PMID 15209160 DOI: 10.1023/B:Modi.0000025652.55320.16  0.59
2003 Ernst JT, Becerril J, Park HS, Yin H, Hamilton AD. Design and application of an alpha-helix-mimetic scaffold based on an oligoamide-foldamer strategy: antagonism of the Bak BH3/Bcl-xL complex. Angewandte Chemie (International Ed. in English). 42: 535-9. PMID 12569483 DOI: 10.1002/Anie.200390154  0.684
2002 Ernst JT, Kutzki O, Debnath AK, Jiang S, Lu H, Hamilton AD. Design of a protein surface antagonist based on alpha-helix mimicry: inhibition of gp41 assembly and viral fusion. Angewandte Chemie (International Ed. in English). 41: 278-81. PMID 12491408 DOI: 10.1002/1521-3773(20020118)41:2<278::Aid-Anie278>3.0.Co;2-A  0.635
2002 Zhao Q, Ernst JT, Hamilton AD, Debnath AK, Jiang S. XTT formazan widely used to detect cell viability inhibits HIV type 1 infection in vitro by targeting gp41. Aids Research and Human Retroviruses. 18: 989-97. PMID 12396451 DOI: 10.1089/08892220260235353  0.464
2002 Kutzki O, Park HS, Ernst JT, Orner BP, Yin H, Hamilton AD. Development of a potent Bcl-x(L) antagonist based on alpha-helix mimicry. Journal of the American Chemical Society. 124: 11838-9. PMID 12358513 DOI: 10.1021/Ja026861K  0.687
2001 Orner BP, Ernst JT, Hamilton AD. Toward proteomimetics: terphenyl derivatives as structural and functional mimics of extended regions of an alpha-helix. Journal of the American Chemical Society. 123: 5382-3. PMID 11457415 DOI: 10.1021/Ja0025548  0.677
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