Year |
Citation |
Score |
2011 |
Szu PH, Govindarajan S, Meehan MJ, Das A, Nguyen DD, Dorrestein PC, Minshull J, Khosla C. Analysis of the ketosynthase-chain length factor heterodimer from the fredericamycin polyketide synthase. Chemistry & Biology. 18: 1021-31. PMID 21867917 DOI: 10.1016/J.Chembiol.2011.07.015 |
0.476 |
|
2011 |
Javidpour P, Das A, Khosla C, Tsai SC. Structural and biochemical studies of the hedamycin type II polyketide ketoreductase (HedKR): molecular basis of stereo- and regiospecificities. Biochemistry. 50: 7426-39. PMID 21776967 DOI: 10.1021/Bi2006866 |
0.48 |
|
2010 |
Das A, Szu PH, Fitzgerald JT, Khosla C. Mechanism and engineering of polyketide chain initiation in fredericamycin biosynthesis. Journal of the American Chemical Society. 132: 8831-3. PMID 20540492 DOI: 10.1021/Ja102517Q |
0.482 |
|
2010 |
Tahanian E, Lord-Dufour S, Das A, Khosla C, Roy R, Annabi B. Inhibition of tubulogenesis and of carcinogen-mediated signaling in brain endothelial cells highlight the antiangiogenic properties of a mumbaistatin analog. Chemical Biology & Drug Design. 75: 481-8. PMID 20486934 DOI: 10.1111/J.1747-0285.2010.00961.X |
0.463 |
|
2009 |
Das A, Khosla C. In vivo and in vitro analysis of the hedamycin polyketide synthase. Chemistry & Biology. 16: 1197-207. PMID 19942143 DOI: 10.1016/J.Chembiol.2009.11.005 |
0.477 |
|
2009 |
Das A, Khosla C. Biosynthesis of aromatic polyketides in bacteria. Accounts of Chemical Research. 42: 631-9. PMID 19292437 DOI: 10.1021/Ar8002249 |
0.493 |
|
2009 |
Lord-Dufour S, Copland IB, Levros LC, Post M, Das A, Khosla C, Galipeau J, Rassart E, Annabi B. Evidence for transcriptional regulation of the glucose-6-phosphate transporter by HIF-1alpha: Targeting G6PT with mumbaistatin analogs in hypoxic mesenchymal stromal cells. Stem Cells (Dayton, Ohio). 27: 489-97. PMID 19074414 DOI: 10.1634/Stemcells.2008-0855 |
0.45 |
|
2007 |
Lee TS, Das A, Khosla C. Structure-activity relationships of semisynthetic mumbaistatin analogs. Bioorganic & Medicinal Chemistry. 15: 5207-18. PMID 17524653 DOI: 10.1016/J.Bmc.2007.05.019 |
0.56 |
|
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