Larry Goldstein - Publications

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52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Young JE, Boulanger-Weill J, Williams DA, Woodruff G, Buen F, Revilla AC, Herrera C, Israel MA, Yuan SH, Edland SD, Goldstein LS. Elucidating molecular phenotypes caused by the SORL1 Alzheimer's disease genetic risk factor using human induced pluripotent stem cells. Cell Stem Cell. 16: 373-85. PMID 25772071 DOI: 10.1016/J.Stem.2015.02.004  0.489
2014 Liu Q, Waltz S, Woodruff G, Ouyang J, Israel MA, Herrera C, Sarsoza F, Tanzi RE, Koo EH, Ringman JM, Goldstein LS, Wagner SL, Yuan SH. Effect of potent γ-secretase modulator in human neurons derived from multiple presenilin 1-induced pluripotent stem cell mutant carriers. Jama Neurology. 71: 1481-9. PMID 25285942 DOI: 10.1001/Jamaneurol.2014.2482  0.488
2014 Encalada SE, Goldstein LS. Biophysical challenges to axonal transport: motor-cargo deficiencies and neurodegeneration. Annual Review of Biophysics. 43: 141-69. PMID 24702007 DOI: 10.1146/Annurev-Biophys-051013-022746  0.321
2014 Otero MG, Alloatti M, Cromberg LE, Almenar-Queralt A, Encalada SE, Pozo Devoto VM, Bruno L, Goldstein LS, Falzone TL. Fast axonal transport of the proteasome complex depends on membrane interaction and molecular motor function. Journal of Cell Science. 127: 1537-49. PMID 24522182 DOI: 10.1242/Jcs.140780  0.317
2013 Duncan JE, Lytle NK, Zuniga A, Goldstein LS. The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila. Plos One. 8: e68324. PMID 23840848 DOI: 10.1371/journal.pone.0068324  0.338
2013 Gunawardena S, Yang G, Goldstein LS. Presenilin controls kinesin-1 and dynein function during APP-vesicle transport in vivo. Human Molecular Genetics. 22: 3828-43. PMID 23710041 DOI: 10.1093/Hmg/Ddt237  0.596
2013 Weaver C, Leidel C, Szpankowski L, Farley NM, Shubeita GT, Goldstein LS. Endogenous GSK-3/shaggy regulates bidirectional axonal transport of the amyloid precursor protein. Traffic (Copenhagen, Denmark). 14: 295-308. PMID 23279138 DOI: 10.1111/Tra.12037  0.351
2012 Szpankowski L, Encalada SE, Goldstein LS. Subpixel colocalization reveals amyloid precursor protein-dependent kinesin-1 and dynein association with axonal vesicles. Proceedings of the National Academy of Sciences of the United States of America. 109: 8582-7. PMID 22582169 DOI: 10.1073/Pnas.1120510109  0.35
2012 Reis GF, Yang G, Szpankowski L, Weaver C, Shah SB, Robinson JT, Hays TS, Danuser G, Goldstein LS. Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila. Molecular Biology of the Cell. 23: 1700-14. PMID 22398725 DOI: 10.1091/Mbc.E11-11-0938  0.347
2012 Israel MA, Yuan SH, Bardy C, Reyna SM, Mu Y, Herrera C, Hefferan MP, Van Gorp S, Nazor KL, Boscolo FS, Carson CT, Laurent LC, Marsala M, Gage FH, Remes AM, ... ... Goldstein LS, et al. Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. Nature. 482: 216-20. PMID 22278060 DOI: 10.1038/Nature10821  0.498
2011 Henthorn KS, Roux MS, Herrera C, Goldstein LS. A role for kinesin heavy chain in controlling vesicle transport into dendrites in Drosophila. Molecular Biology of the Cell. 22: 4038-46. PMID 21880894 DOI: 10.1091/mbc.E10-07-0572  0.326
2011 Israel MA, Goldstein LS. Capturing Alzheimer's disease genomes with induced pluripotent stem cells: prospects and challenges. Genome Medicine. 3: 49. PMID 21867573 DOI: 10.1186/Gm265  0.489
2011 Yuan SH, Martin J, Elia J, Flippin J, Paramban RI, Hefferan MP, Vidal JG, Mu Y, Killian RL, Israel MA, Emre N, Marsala S, Marsala M, Gage FH, Goldstein LS, et al. Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells. Plos One. 6: e17540. PMID 21407814 DOI: 10.1371/Journal.Pone.0017540  0.465
2011 Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J, Canto I, Giorgetti A, Israel MA, Kiskinis E, Lee JH, Loh YH, Manos PD, Montserrat N, Panopoulos AD, ... ... Goldstein LS, et al. Somatic coding mutations in human induced pluripotent stem cells. Nature. 471: 63-7. PMID 21368825 DOI: 10.1038/Nature09805  0.487
2011 Encalada SE, Szpankowski L, Xia CH, Goldstein LS. Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles. Cell. 144: 551-65. PMID 21335237 DOI: 10.1016/J.Cell.2011.01.021  0.314
2011 Kim JE, O'Sullivan ML, Sanchez CA, Hwang M, Israel MA, Brennand K, Deerinck TJ, Goldstein LS, Gage FH, Ellisman MH, Ghosh A. Investigating synapse formation and function using human pluripotent stem cell-derived neurons. Proceedings of the National Academy of Sciences of the United States of America. 108: 3005-10. PMID 21278334 DOI: 10.1073/Pnas.1007753108  0.482
2010 Falzone TL, Gunawardena S, McCleary D, Reis GF, Goldstein LS. Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies. Human Molecular Genetics. 19: 4399-408. PMID 20817925 DOI: 10.1093/Hmg/Ddq363  0.574
2010 Lian I, Kim J, Okazawa H, Zhao J, Zhao B, Yu J, Chinnaiyan A, Israel MA, Goldstein LS, Abujarour R, Ding S, Guan KL. The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation. Genes & Development. 24: 1106-18. PMID 20516196 DOI: 10.1101/Gad.1903310  0.48
2009 Abe N, Almenar-Queralt A, Lillo C, Shen Z, Lozach J, Briggs SP, Williams DS, Goldstein LS, Cavalli V. Sunday driver interacts with two distinct classes of axonal organelles. The Journal of Biological Chemistry. 284: 34628-39. PMID 19801628 DOI: 10.1074/Jbc.M109.035022  0.3
2008 Her LS, Goldstein LS. Enhanced sensitivity of striatal neurons to axonal transport defects induced by mutant huntingtin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13662-72. PMID 19074039 DOI: 10.1523/JNEUROSCI.4144-08.2008  0.306
2008 Stokin GB, Almenar-Queralt A, Gunawardena S, Rodrigues EM, Falzone T, Kim J, Lillo C, Mount SL, Roberts EA, McGowan E, Williams DS, Goldstein LS. Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides. Human Molecular Genetics. 17: 3474-86. PMID 18694898 DOI: 10.1093/Hmg/Ddn240  0.564
2007 Haghnia M, Cavalli V, Shah SB, Schimmelpfeng K, Brusch R, Yang G, Herrera C, Pilling A, Goldstein LS. Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment. Molecular Biology of the Cell. 18: 2081-9. PMID 17360970 DOI: 10.1091/Mbc.E06-08-0695  0.305
2006 Stokin GB, Goldstein LS. Axonal transport and Alzheimer's disease. Annual Review of Biochemistry. 75: 607-27. PMID 16756504 DOI: 10.1146/Annurev.Biochem.75.103004.142637  0.317
2006 Gunawardena S, Goldstein L. O4-02-02 Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.301  0.478
2005 Stokin GB, Lillo C, Falzone TL, Brusch RG, Rockenstein E, Mount SL, Raman R, Davies P, Masliah E, Williams DS, Goldstein LS. Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease. Science (New York, N.Y.). 307: 1282-8. PMID 15731448 DOI: 10.1126/Science.1105681  0.301
2005 Gunawardena S, Goldstein LS. Polyglutamine diseases and transport problems: deadly traffic jams on neuronal highways. Archives of Neurology. 62: 46-51. PMID 15642849 DOI: 10.1001/archneur.62.1.46  0.549
2004 Gunawardena S, Goldstein LS. Cargo-carrying motor vehicles on the neuronal highway: transport pathways and neurodegenerative disease. Journal of Neurobiology. 58: 258-71. PMID 14704957 DOI: 10.1002/neu.10319  0.592
2003 Gunawardena S, Her LS, Brusch RG, Laymon RA, Niesman IR, Gordesky-Gold B, Sintasath L, Bonini NM, Goldstein LS. Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron. 40: 25-40. PMID 14527431 DOI: 10.1016/S0896-6273(03)00594-4  0.591
2001 Gunawardena S, Goldstein LS. Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila. Neuron. 32: 389-401. PMID 11709151 DOI: 10.1016/S0896-6273(01)00496-2  0.604
2001 Almenar-Queralt A, Goldstein LS. Linkers, packages and pathways: new concepts in axonal transport. Current Opinion in Neurobiology. 11: 550-7. PMID 11595487  0.322
2001 Yang Z, Roberts EA, Goldstein LS. Functional analysis of mouse kinesin motor Kif3C. Molecular and Cellular Biology. 21: 5306-11. PMID 11463814 DOI: 10.1128/MCB.21.16.5306-5311.2001  0.3
2001 Yang Z, Roberts EA, Goldstein LS. Functional analysis of mouse C-terminal kinesin motor KifC2. Molecular and Cellular Biology. 21: 2463-6. PMID 11259594 DOI: 10.1128/MCB.21.7.2463-2466.2001  0.356
2001 Yang Z, Xia Ch, Roberts EA, Bush K, Nigam SK, Goldstein LS. Molecular cloning and functional analysis of mouse C-terminal kinesin motor KifC3. Molecular and Cellular Biology. 21: 765-70. PMID 11154264 DOI: 10.1128/Mcb.21.3.765-770.2001  0.313
2000 Bowman AB, Kamal A, Ritchings BW, Philp AV, McGrail M, Gindhart JG, Goldstein LS. Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein. Cell. 103: 583-94. PMID 11106729 DOI: 10.1016/S0092-8674(00)00162-8  0.748
2000 Goldstein LS, Gunawardena S. Flying through the drosophila cytoskeletal genome. The Journal of Cell Biology. 150: F63-8. PMID 10908588 DOI: 10.1083/Jcb.150.2.F63  0.493
2000 Yucel JK, Marszalek JD, McIntosh JR, Goldstein LS, Cleveland DW, Philp AV. CENP-meta, an essential kinetochore kinesin required for the maintenance of metaphase chromosome alignment in Drosophila. The Journal of Cell Biology. 150: 1-11. PMID 10893249 DOI: 10.1083/Jcb.150.1.1  0.563
1999 Goldstein LS, Philp AV. The road less traveled: emerging principles of kinesin motor utilization. Annual Review of Cell and Developmental Biology. 15: 141-83. PMID 10611960 DOI: 10.1146/annurev.cellbio.15.1.141  0.588
1999 Ray K, Perez SE, Yang Z, Xu J, Ritchings BW, Steller H, Goldstein LS. Kinesin-II is required for axonal transport of choline acetyltransferase in Drosophila. The Journal of Cell Biology. 147: 507-18. PMID 10545496 DOI: 10.1083/jcb.147.3.507  0.552
1999 Bowman AB, Patel-King RS, Benashski SE, McCaffery JM, Goldstein LS, King SM. Drosophila roadblock and Chlamydomonas LC7: a conserved family of dynein-associated proteins involved in axonal transport, flagellar motility, and mitosis. The Journal of Cell Biology. 146: 165-80. PMID 10402468 DOI: 10.1083/jcb.146.1.165  0.54
1999 Marszalek JR, Weiner JA, Farlow SJ, Chun J, Goldstein LS. Novel dendritic kinesin sorting identified by different process targeting of two related kinesins: KIF21A and KIF21B. The Journal of Cell Biology. 145: 469-79. PMID 10225949 DOI: 10.1083/jcb.145.3.469  0.325
1998 Gindhart JG, Desai CJ, Beushausen S, Zinn K, Goldstein LS. Kinesin light chains are essential for axonal transport in Drosophila. The Journal of Cell Biology. 141: 443-54. PMID 9548722 DOI: 10.1083/Jcb.141.2.443  0.757
1998 Sakowicz R, Berdelis MS, Ray K, Blackburn CL, Hopmann C, Faulkner DJ, Goldstein LS. A marine natural product inhibitor of kinesin motors. Science (New York, N.Y.). 280: 292-5. PMID 9535660 DOI: 10.1126/Science.280.5361.292  0.523
1997 Hanlon DW, Yang Z, Goldstein LS. Characterization of KIFC2, a neuronal kinesin superfamily member in mouse. Neuron. 18: 439-51. PMID 9115737  0.353
1997 Pereira AJ, Dalby B, Stewart RJ, Doxsey SJ, Goldstein LS. Mitochondrial association of a plus end-directed microtubule motor expressed during mitosis in Drosophila. The Journal of Cell Biology. 136: 1081-90. PMID 9060472 DOI: 10.1083/Jcb.136.5.1081  0.756
1996 Gindhart JG, Goldstein LS. Armadillo repeats in the SpKAP115 subunit of kinesin-II. Trends in Cell Biology. 6: 415-6. PMID 15157510 DOI: 10.1016/S0962-8924(96)20037-6  0.695
1996 Gindhart JG, Goldstein LS. Tetratrico peptide repeats are present in the kinesin light chain. Trends in Biochemical Sciences. 21: 52-3. PMID 8851660 DOI: 10.1016/0968-0004(96)80865-6  0.694
1996 Desai CJ, Gindhart JG, Goldstein LS, Zinn K. Receptor tyrosine phosphatases are required for motor axon guidance in the Drosophila embryo. Cell. 84: 599-609. PMID 8598046 DOI: 10.1016/S0092-8674(00)81035-1  0.752
1995 Barton NR, Pereira AJ, Goldstein LS. Motor activity and mitotic spindle localization of the Drosophila kinesin-like protein KLP61F. Molecular Biology of the Cell. 6: 1563-74. PMID 8589456  0.512
1995 Dalby B, Pereira AJ, Goldstein LS. An inverse PCR screen for the detection of P element insertions in cloned genomic intervals in Drosophila melanogaster. Genetics. 139: 757-66. PMID 7713430  0.718
1994 Pesavento PA, Stewart RJ, Goldstein LS. Characterization of the KLP68D kinesin-like protein in Drosophila: possible roles in axonal transport. The Journal of Cell Biology. 127: 1041-8. PMID 7525600 DOI: 10.1083/Jcb.127.4.1041  0.332
1993 Heck MM, Pereira A, Pesavento P, Yannoni Y, Spradling AC, Goldstein LS. The kinesin-like protein KLP61F is essential for mitosis in Drosophila. The Journal of Cell Biology. 123: 665-79. PMID 8227131  0.493
1992 Pereira A, Doshen J, Tanaka E, Goldstein LS. Genetic analysis of a Drosophila microtubule-associated protein. The Journal of Cell Biology. 116: 377-83. PMID 1309812  0.401
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