Steven L. McKnight - Publications

Affiliations: 
Biochemistry University of Texas Southwestern Medical Center, Dallas, TX, United States 
Area:
regulation of gene expression
Website:
http://profiles.utsouthwestern.edu/profile/14812/steven-mcknight.html

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Year Citation  Score
2021 Kato M, Tu BP, McKnight SL. Redox-mediated regulation of low complexity domain self-association. Current Opinion in Genetics & Development. 67: 111-118. PMID 33454579 DOI: 10.1016/j.gde.2020.12.006  0.596
2020 Lin Y, Zhou X, Kato M, Liu D, Ghaemmaghami S, Tu BP, McKnight SL. Redox-mediated regulation of an evolutionarily conserved cross-β structure formed by the TDP43 low complexity domain. Proceedings of the National Academy of Sciences of the United States of America. PMID 33144500 DOI: 10.1073/pnas.2012216117  0.586
2020 Sysoev VO, Kato M, Sutherland L, Hu R, McKnight SL, Murray DT. Dynamic structural order of a low-complexity domain facilitates assembly of intermediate filaments. Proceedings of the National Academy of Sciences of the United States of America. PMID 32907935 DOI: 10.1073/pnas.2010000117  0.313
2019 Kato M, Yang YS, Sutter BM, Wang Y, McKnight SL, Tu BP. Redox State Controls Phase Separation of the Yeast Ataxin-2 Protein via Reversible Oxidation of Its Methionine-Rich Low-Complexity Domain. Cell. PMID 30982603 DOI: 10.1016/J.Cell.2019.02.044  0.623
2019 Pieper AA, McKnight SL. Benefits of Enhancing Nicotinamide Adenine Dinucleotide Levels in Damaged or Diseased Nerve Cells. Cold Spring Harbor Symposia On Quantitative Biology. PMID 30787047 DOI: 10.1101/sqb.2018.83.037622  0.585
2018 Huang Z, Zhang M, Plec AA, Estill SJ, Cai L, Repa JJ, McKnight SL, Tu BP. ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolism. Proceedings of the National Academy of Sciences of the United States of America. PMID 30228117 DOI: 10.1073/Pnas.1806635115  0.612
2017 Kato M, McKnight SL. A Solid-State Conceptualization of Information Transfer from Gene to Message to Protein. Annual Review of Biochemistry. PMID 29195049 DOI: 10.1146/annurev-biochem-061516-044700  0.361
2017 Murray DT, Kato M, Lin Y, Thurber KR, Hung I, McKnight SL, Tycko R. Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains. Cell. PMID 28942918 DOI: 10.1016/j.cell.2017.08.048  0.344
2017 Kato M, Lin Y, McKnight SL. Cross-β polymerization and hydrogel formation by low-complexity sequence proteins. Methods (San Diego, Calif.). PMID 28624540 DOI: 10.1016/j.ymeth.2017.06.011  0.335
2017 Shi KY, Mori E, Nizami ZF, Lin Y, Kato M, Xiang S, Wu LC, Ding M, Yu Y, Gall JG, McKnight SL. Toxic PRn poly-dipeptides encoded by the C9orf72 repeat expansion block nuclear import and export. Proceedings of the National Academy of Sciences of the United States of America. PMID 28069952 DOI: 10.1073/Pnas.1620293114  0.551
2016 Kato M, McKnight SL. Cross-β Polymerization of Low Complexity Sequence Domains. Cold Spring Harbor Perspectives in Biology. PMID 27836835 DOI: 10.1101/cshperspect.a023598  0.37
2016 Lin Y, Mori E, Kato M, Xiang S, Wu L, Kwon I, McKnight SL. Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers. Cell. 167: 789-802.e12. PMID 27768897 DOI: 10.1016/j.cell.2016.10.003  0.336
2015 Xiang S, Kato M, Wu LC, Lin Y, Ding M, Zhang Y, Yu Y, McKnight SL. The LC Domain of hnRNPA2 Adopts Similar Conformations in Hydrogel Polymers, Liquid-like Droplets, and Nuclei. Cell. 163: 829-39. PMID 26544936 DOI: 10.1016/J.Cell.2015.10.040  0.351
2014 Comerford SA, Huang Z, Du X, Wang Y, Cai L, Witkiewicz AK, Walters H, Tantawy MN, Fu A, Manning HC, Horton JD, Hammer RE, McKnight SL, Tu BP. Acetate dependence of tumors. Cell. 159: 1591-602. PMID 25525877 DOI: 10.1016/J.Cell.2014.11.020  0.597
2014 Yin TC, Britt JK, De Jesús-Cortés H, Lu Y, Genova RM, Khan MZ, Voorhees JR, Shao J, Katzman AC, Huntington PJ, Wassink C, McDaniel L, Newell EA, Dutca LM, Naidoo J, ... ... McKnight SL, et al. P7C3 neuroprotective chemicals block axonal degeneration and preserve function after traumatic brain injury. Cell Reports. 8: 1731-40. PMID 25220467 DOI: 10.1016/J.Celrep.2014.08.030  0.742
2014 Wang G, Han T, Nijhawan D, Theodoropoulos P, Naidoo J, Yadavalli S, Mirzaei H, Pieper AA, Ready JM, McKnight SL. P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage. Cell. 158: 1324-34. PMID 25215490 DOI: 10.1016/J.Cell.2014.07.040  0.576
2014 Kwon I, Xiang S, Kato M, Wu L, Theodoropoulos P, Wang T, Kim J, Yun J, Xie Y, McKnight SL. Poly-dipeptides encoded by the C9orf72 repeats bind nucleoli, impede RNA biogenesis, and kill cells. Science (New York, N.Y.). 345: 1139-45. PMID 25081482 DOI: 10.1126/science.1254917  0.369
2014 McKnight SL. Please keep me 2uned to PKM2. Molecular Cell. 53: 683-4. PMID 24606916 DOI: 10.1016/j.molcel.2014.02.022  0.304
2014 Pieper AA, McKnight SL, Ready JM. P7C3 and an unbiased approach to drug discovery for neurodegenerative diseases. Chemical Society Reviews. 43: 6716-26. PMID 24514864 DOI: 10.1039/C3Cs60448A  0.557
2014 Laxman S, Tu BP, McKnight SL. Concerted effort: oscillations in global gene expression during nematode development. Molecular Cell. 53: 363-4. PMID 24507713 DOI: 10.1016/J.Molcel.2014.01.023  0.714
2014 Kwon I, Kato M, Xiang S, Wu L, Theodoropoulos P, Mirzaei H, Han T, Xie S, Corden J, McKnight S. Phosphorylation-Regulated Binding of RNA Polymerase II to Fibrous Polymers of Low-Complexity Domains Cell. 156: 374. DOI: 10.1016/J.Cell.2014.01.002  0.679
2013 Kwon I, Kato M, Xiang S, Wu L, Theodoropoulos P, Mirzaei H, Han T, Xie S, Corden JL, McKnight SL. Phosphorylation-regulated binding of RNA polymerase II to fibrous polymers of low-complexity domains. Cell. 155: 1049-60. PMID 24267890 DOI: 10.1016/J.Cell.2013.10.033  0.709
2012 De Jesús-Cortés H, Xu P, Drawbridge J, Estill SJ, Huntington P, Tran S, Britt J, Tesla R, Morlock L, Naidoo J, Melito LM, Wang G, Williams NS, Ready JM, McKnight SL, et al. Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. 109: 17010-5. PMID 23027934 DOI: 10.1073/Pnas.1213956109  0.56
2012 Tesla R, Wolf HP, Xu P, Drawbridge J, Estill SJ, Huntington P, McDaniel L, Knobbe W, Burket A, Tran S, Starwalt R, Morlock L, Naidoo J, Williams NS, Ready JM, ... McKnight SL, et al. Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 109: 17016-21. PMID 23027932 DOI: 10.1073/Pnas.1213960109  0.562
2012 Han TW, Kato M, Xie S, Wu LC, Mirzaei H, Pei J, Chen M, Xie Y, Allen J, Xiao G, McKnight SL. Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies. Cell. 149: 768-79. PMID 22579282 DOI: 10.1016/J.Cell.2012.04.016  0.696
2012 Kato M, Han TW, Xie S, Shi K, Du X, Wu LC, Mirzaei H, Goldsmith EJ, Longgood J, Pei J, Grishin NV, Frantz DE, Schneider JW, Chen S, Li L, ... ... McKnight SL, et al. Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels. Cell. 149: 753-67. PMID 22579281 DOI: 10.1016/J.Cell.2012.04.017  0.693
2012 McKnight S, Beyer A, Gall J. Retrospective. Oscar Miller (1925-2012). Science (New York, N.Y.). 335: 1457. PMID 22442474 DOI: 10.1126/science.1220681  0.627
2011 McKnight SL. Back to the future: molecular biology meets metabolism. Cold Spring Harbor Symposia On Quantitative Biology. 76: 403-11. PMID 22510749 DOI: 10.1101/sqb.2012.76.013722  0.362
2011 Wang J, Alexander P, McKnight SL. Metabolic specialization of mouse embryonic stem cells. Cold Spring Harbor Symposia On Quantitative Biology. 76: 183-93. PMID 22071264 DOI: 10.1101/sqb.2011.76.010835  0.309
2011 Alexander PB, Wang J, McKnight SL. Targeted killing of a mammalian cell based upon its specialized metabolic state. Proceedings of the National Academy of Sciences of the United States of America. 108: 15828-33. PMID 21896756 DOI: 10.1073/pnas.1111312108  0.315
2011 MacMillan KS, Naidoo J, Liang J, Melito L, Williams NS, Morlock L, Huntington PJ, Estill SJ, Longgood J, Becker GL, McKnight SL, Pieper AA, De Brabander JK, Ready JM. Development of proneurogenic, neuroprotective small molecules. Journal of the American Chemical Society. 133: 1428-37. PMID 21210688 DOI: 10.1021/Ja108211M  0.573
2010 Pieper AA, Xie S, Capota E, Estill SJ, Zhong J, Long JM, Becker GL, Huntington P, Goldman SE, Shen CH, Capota M, Britt JK, Kotti T, Ure K, Brat DJ, ... ... McKnight SL, et al. Discovery of a proneurogenic, neuroprotective chemical. Cell. 142: 39-51. PMID 20603013 DOI: 10.1016/J.Cell.2010.06.018  0.576
2009 Tu BP, McKnight SL. Evidence of carbon monoxide-mediated phase advancement of the yeast metabolic cycle. Proceedings of the National Academy of Sciences of the United States of America. 106: 14293-6. PMID 19706514 DOI: 10.1073/Pnas.0907786106  0.62
2009 Wang J, Alexander P, Wu L, Hammer R, Cleaver O, McKnight SL. Dependence of mouse embryonic stem cells on threonine catabolism. Science (New York, N.Y.). 325: 435-9. PMID 19589965 DOI: 10.1126/science.1173288  0.309
2009 McKnight SL. Abstract IA-18: Mouse embryonic stem cells exist in a unique metabolic state Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-Ia-18  0.338
2007 Tu BP, McKnight SL. The yeast metabolic cycle: insights into the life of a eukaryotic cell. Cold Spring Harbor Symposia On Quantitative Biology. 72: 339-43. PMID 18419291 DOI: 10.1101/Sqb.2007.72.019  0.624
2007 Chen Z, McKnight SL. A conserved DNA damage response pathway responsible for coupling the cell division cycle to the circadian and metabolic cycles. Cell Cycle (Georgetown, Tex.). 6: 2906-12. PMID 18000400 DOI: 10.4161/Cc.6.23.5041  0.321
2007 Tu BP, Mohler RE, Liu JC, Dombek KM, Young ET, Synovec RE, McKnight SL. Cyclic changes in metabolic state during the life of a yeast cell. Proceedings of the National Academy of Sciences of the United States of America. 104: 16886-91. PMID 17940006 DOI: 10.1073/Pnas.0708365104  0.608
2007 Chen Z, Odstrcil EA, Tu BP, McKnight SL. Restriction of DNA replication to the reductive phase of the metabolic cycle protects genome integrity. Science (New York, N.Y.). 316: 1916-9. PMID 17600220 DOI: 10.1126/Science.1140958  0.62
2006 Tu BP, McKnight SL. Metabolic cycles as an underlying basis of biological oscillations. Nature Reviews. Molecular Cell Biology. 7: 696-701. PMID 16823381 DOI: 10.1038/Nrm1980  0.596
2006 Tu BP, Kudlicki A, Rowicka M, McKnight SL. Let the data speak [3] Nature Reviews Molecular Cell Biology. 7: 1-2. DOI: 10.1038/Nrm1980-C3  0.537
2005 Tu BP, Kudlicki A, Rowicka M, McKnight SL. Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes. Science (New York, N.Y.). 310: 1152-8. PMID 16254148 DOI: 10.1126/Science.1120499  0.634
2005 Pieper AA, Wu X, Han TW, Estill SJ, Dang Q, Wu LC, Reece-Fincanon S, Dudley CA, Richardson JA, Brat DJ, McKnight SL. The neuronal PAS domain protein 3 transcription factor controls FGF-mediated adult hippocampal neurogenesis in mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 14052-7. PMID 16172381 DOI: 10.1073/Pnas.0506713102  0.747
2004 Erbel-Sieler C, Dudley C, Zhou Y, Wu X, Estill SJ, Han T, Diaz-Arrastia R, Brunskill EW, Potter SS, McKnight SL. Behavioral and regulatory abnormalities in mice deficient in the NPAS1 and NPAS3 transcription factors. Proceedings of the National Academy of Sciences of the United States of America. 101: 13648-53. PMID 15347806 DOI: 10.1073/Pnas.0405310101  0.687
2003 McKnight S. Gene switching by metabolic enzymes--how did you get on the invitation list? Cell. 114: 150-2. PMID 12887915 DOI: 10.1016/S0092-8674(03)00563-4  0.36
2003 Dudley CA, Erbel-Sieler C, Estill SJ, Reick M, Franken P, Pitts S, McKnight SL. Altered patterns of sleep and behavioral adaptability in NPAS2-deficient mice. Science (New York, N.Y.). 301: 379-83. PMID 12843397 DOI: 10.1126/Science.1082795  0.305
2002 Dioum EM, Rutter J, Tuckerman JR, Gonzalez G, Gilles-Gonzalez MA, McKnight SL. NPAS2: a gas-responsive transcription factor. Science (New York, N.Y.). 298: 2385-7. PMID 12446832 DOI: 10.1126/Science.1078456  0.612
2002 Rutter J, Probst BL, McKnight SL. Coordinate regulation of sugar flux and translation by PAS kinase. Cell. 111: 17-28. PMID 12372297 DOI: 10.1016/S0092-8674(02)00974-1  0.568
2002 Rutter J, Reick M, McKnight SL. Metabolism and the control of circadian rhythms. Annual Review of Biochemistry. 71: 307-31. PMID 12045099 DOI: 10.1146/Annurev.Biochem.71.090501.142857  0.568
2001 McKnight SL. McBindall--a better name for CCAAT/enhancer binding proteins? Cell. 107: 259-61. PMID 11701103 DOI: 10.1016/S0092-8674(01)00543-8  0.37
2001 Bruick RK, McKnight SL. A conserved family of prolyl-4-hydroxylases that modify HIF. Science (New York, N.Y.). 294: 1337-40. PMID 11598268 DOI: 10.1126/science.1066373  0.313
2001 Rutter J, Michnoff CH, Harper SM, Gardner KH, McKnight SL. PAS kinase: an evolutionarily conserved PAS domain-regulated serine/threonine kinase. Proceedings of the National Academy of Sciences of the United States of America. 98: 8991-6. PMID 11459942 DOI: 10.1073/Pnas.161284798  0.592
2001 Reick M, Garcia JA, Dudley C, McKnight SL. NPAS2: an analog of clock operative in the mammalian forebrain. Science (New York, N.Y.). 293: 506-9. PMID 11441147 DOI: 10.1126/science.1060699  0.391
2001 Rutter J, Reick M, Wu LC, McKnight SL. Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors. Science (New York, N.Y.). 293: 510-4. PMID 11441146 DOI: 10.1126/Science.1060698  0.599
2000 Garcia JA, Zhang D, Estill SJ, Michnoff C, Rutter J, Reick M, Scott K, Diaz-Arrastia R, McKnight SL. Impaired cued and contextual memory in NPAS2-deficient mice. Science (New York, N.Y.). 288: 2226-30. PMID 10864874 DOI: 10.1126/Science.288.5474.2226  0.595
1998 Tian H, Hammer RE, Matsumoto AM, Russell DW, McKnight SL. The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development. Genes & Development. 12: 3320-4. PMID 9808618 DOI: 10.1101/Gad.12.21.3320  0.302
1998 Batchelor AH, Piper DE, de la Brousse FC, McKnight SL, Wolberger C. The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNA. Science (New York, N.Y.). 279: 1037-41. PMID 9461436 DOI: 10.1126/Science.279.5353.1037  0.334
1997 Zhou YD, Barnard M, Tian H, Li X, Ring HZ, Francke U, Shelton J, Richardson J, Russell DW, McKnight SL. Molecular characterization of two mammalian bHLH-PAS domain proteins selectively expressed in the central nervous system. Proceedings of the National Academy of Sciences of the United States of America. 94: 713-8. PMID 9012850 DOI: 10.1073/Pnas.94.2.713  0.34
1997 Tian H, McKnight SL, Russell DW. Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes & Development. 11: 72-82. PMID 9000051 DOI: 10.1101/Gad.11.1.72  0.377
1996 Schindler U, Hoey T, McKnight SL. Differentiation of T-helper lymphocytes: selective regulation by members of the STAT family of transcription factors. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 1: 507-15. PMID 9078381 DOI: 10.1046/J.1365-2443.1996.D01-263.X  0.333
1996 Yeh WC, Hou J, McKnight SL. Purification and characterization of gene-specific transcription factors: C/EBP, GABP, and IL-4 stat. Methods in Enzymology. 274: 101-12. PMID 8902798 DOI: 10.1016/S0076-6879(96)74010-7  0.369
1996 McKnight SL. Transcription revisited: a commentary on the 1995 Cold Spring Harbor Laboratory meeting, "Mechanisms of Eukaryotic Transcription". Genes & Development. 10: 367-81. PMID 8600022 DOI: 10.1101/Gad.10.4.367  0.31
1995 Yeh WC, Cao Z, Classon M, McKnight SL. Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins. Genes & Development. 9: 168-81. PMID 7531665 DOI: 10.1101/Gad.9.2.168  0.303
1995 Yeh WC, Li TK, Bierer BE, McKnight SL. Identification and characterization of an immunophilin expressed during the clonal expansion phase of adipocyte differentiation. Proceedings of the National Academy of Sciences of the United States of America. 92: 11081-5. PMID 7479941 DOI: 10.1073/Pnas.92.24.11081  0.32
1995 McKnight S, Schibler U. Differentiation and gene regulation Current Opinion in Genetics and Development. 5: 549-551. DOI: 10.1016/0959-437X(95)80021-2  0.317
1993 de la Brousse FC, McKnight SL. Glimpses of allostery in the control of eukaryotic gene expression. Trends in Genetics : Tig. 9: 151-4. PMID 8337748 DOI: 10.1016/0168-9525(93)90149-C  0.385
1992 Brown TA, McKnight SL. Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins. Genes & Development. 6: 2502-12. PMID 1340465 DOI: 10.1101/Gad.6.12B.2502  0.307
1992 Thompson CC, McKnight SL. Anatomy of an enhancer Trends in Genetics. 8: 232-236. DOI: 10.1016/0168-9525(92)90392-H  0.645
1991 Umek RM, Friedman AD, McKnight SL. CCAAT-enhancer binding protein: a component of a differentiation switch. Science (New York, N.Y.). 251: 288-92. PMID 1987644 DOI: 10.1126/Science.1987644  0.311
1991 LaMarco K, Thompson CC, Byers BP, Walton EM, McKnight SL. Identification of Ets- and notch-related subunits in GA binding protein. Science (New York, N.Y.). 253: 789-92. PMID 1876836 DOI: 10.1126/Science.1876836  0.634
1991 Thompson CC, Brown TA, McKnight SL. Convergence of Ets- and notch-related structural motifs in a heteromeric DNA binding complex. Science (New York, N.Y.). 253: 762-8. PMID 1876833 DOI: 10.1126/Science.1876833  0.623
1991 McKnight SL. Molecular zippers in gene regulation. Scientific American. 264: 54-64. PMID 1876825 DOI: 10.1038/Scientificamerican0491-54  0.32
1991 Lamb P, McKnight SL. Diversity and specificity in transcriptional regulation: the benefits of heterotypic dimerization. Trends in Biochemical Sciences. 16: 417-22. PMID 1776171 DOI: 10.1016/0968-0004(91)90167-T  0.342
1990 Friedman AD, McKnight SL. Identification of two polypeptide segments of CCAAT/enhancer-binding protein required for transcriptional activation of the serum albumin gene. Genes & Development. 4: 1416-26. PMID 2227417 DOI: 10.1101/Gad.4.8.1416  0.386
1990 Shuman JD, Vinson CR, McKnight SL. Evidence of changes in protease sensitivity and subunit exchange rate on DNA binding by C/EBP. Science (New York, N.Y.). 249: 771-4. PMID 2202050 DOI: 10.1126/Science.2202050  0.311
1989 Birkenmeier EH, Gwynn B, Howard S, Jerry J, Gordon JI, Landschulz WH, McKnight SL. Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein. Genes & Development. 3: 1146-56. PMID 2792758 DOI: 10.1101/Gad.3.8.1146  0.346
1989 McKnight SL, Lane MD, Gluecksohn-Waelsch S. Is CCAAT/enhancer-binding protein a central regulator of energy metabolism? Genes & Development. 3: 2021-4. PMID 2697636 DOI: 10.1101/gad.3.12b.2021  0.308
1989 Vinson CR, Sigler PB, McKnight SL. Scissors-grip model for DNA recognition by a family of leucine zipper proteins. Science (New York, N.Y.). 246: 911-6. PMID 2683088 DOI: 10.1126/Science.2683088  0.337
1989 Johnson PF, McKnight SL. Eukaryotic transcriptional regulatory proteins. Annual Review of Biochemistry. 58: 799-839. PMID 2673023 DOI: 10.1146/annurev.bi.58.070189.004055  0.302
1989 LaMarco KL, McKnight SL. Purification of a set of cellular polypeptides that bind to the purine-rich cis-regulatory element of herpes simplex virus immediate early genes. Genes & Development. 3: 1372-83. PMID 2558055 DOI: 10.1101/Gad.3.9.1372  0.364
1989 Friedman AD, Landschulz WH, McKnight SL. CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells. Genes & Development. 3: 1314-22. PMID 2558052 DOI: 10.1101/Gad.3.9.1314  0.335
1989 Agre P, Johnson PF, McKnight SL. Cognate DNA binding specificity retained after leucine zipper exchange between GCN4 and C/EBP. Science (New York, N.Y.). 246: 922-6. PMID 2530632 DOI: 10.1126/Science.2530632  0.359
1989 Landschulz WH, Johnson PF, McKnight SL. The DNA binding domain of the rat liver nuclear protein C/EBP is bipartite. Science (New York, N.Y.). 243: 1681-8. PMID 2494700 DOI: 10.1126/Science.2494700  0.349
1988 Landschulz WH, Johnson PF, McKnight SL. The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. Science (New York, N.Y.). 240: 1759-64. PMID 3289117 DOI: 10.1126/Science.3289117  0.318
1988 McKnight SL, Landschulz WH, Johnson PF. Prediction of a dimerization surface common to a new class of sequence-specific DNA binding proteins. Current Topics in Microbiology and Immunology. 141: 186-8. PMID 3215050 DOI: 10.1007/978-3-642-74006-0_25  0.359
1988 Vinson CR, LaMarco KL, Johnson PF, Landschulz WH, McKnight SL. In situ detection of sequence-specific DNA binding activity specified by a recombinant bacteriophage. Genes & Development. 2: 801-6. PMID 3061875 DOI: 10.1101/Gad.2.7.801  0.314
1988 Landschulz WH, Johnson PF, Adashi EY, Graves BJ, McKnight SL. Isolation of a recombinant copy of the gene encoding C/EBP. Genes & Development. 2: 786-800. PMID 2850264 DOI: 10.1101/Gad.2.7.786  0.599
1988 Friedman AD, Triezenberg SJ, McKnight SL. Expression of a truncated viral trans-activator selectively impedes lytic infection by its cognate virus. Nature. 335: 452-4. PMID 2843776 DOI: 10.1038/335452a0  0.367
1988 Triezenberg SJ, LaMarco KL, McKnight SL. Evidence of DNA: protein interactions that mediate HSV-1 immediate early gene activation by VP16. Genes & Development. 2: 730-42. PMID 2843426 DOI: 10.1101/Gad.2.6.730  0.385
1988 Triezenberg SJ, Kingsbury RC, McKnight SL. Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression. Genes & Development. 2: 718-29. PMID 2843425 DOI: 10.1101/Gad.2.6.718  0.395
1987 Johnson PF, Landschulz WH, Graves BJ, McKnight SL. Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses. Genes & Development. 1: 133-46. PMID 2824279 DOI: 10.1101/Gad.1.2.133  0.572
1987 Weinheimer SP, McKnight SL. Transcriptional and post-transcriptional controls establish the cascade of herpes simplex virus protein synthesis. Journal of Molecular Biology. 195: 819-33. PMID 2821283 DOI: 10.1016/0022-2836(87)90487-6  0.356
1986 McKnight S, Tjian R. Transcriptional selectivity of viral genes in mammalian cells. Cell. 46: 795-805. PMID 3530495 DOI: 10.1016/0092-8674(86)90061-9  0.342
1986 Coen DM, Weinheimer SP, McKnight SL. A genetic approach to promoter recognition during trans induction of viral gene expression. Science (New York, N.Y.). 234: 53-9. PMID 3018926 DOI: 10.1126/Science.3018926  0.373
1986 Graves BJ, Johnson PF, McKnight SL. Homologous recognition of a promoter domain common to the MSV LTR and the HSV tk gene. Cell. 44: 565-76. PMID 3004739 DOI: 10.1016/0092-8674(86)90266-7  0.618
1985 Graves BJ, Eisenberg SP, Coen DM, McKnight SL. Alternate utilization of two regulatory domains within the Moloney murine sarcoma virus long terminal repeat. Molecular and Cellular Biology. 5: 1959-68. PMID 3018540 DOI: 10.1128/Mcb.5.8.1959  0.566
1985 Graves BJ, Eisenman RN, McKnight SL. Delineation of transcriptional control signals within the Moloney murine sarcoma virus long terminal repeat. Molecular and Cellular Biology. 5: 1948-58. PMID 3018539 DOI: 10.1128/Mcb.5.8.1948  0.582
1985 Eisenberg SP, Coen DM, McKnight SL. Promoter domains required for expression of plasmid-borne copies of the herpes simplex virus thymidine kinase gene in virus-infected mouse fibroblasts and microinjected frog oocytes. Molecular and Cellular Biology. 5: 1940-7. PMID 3018538 DOI: 10.1128/Mcb.5.8.1940  0.363
1984 Merrill GF, Hauschka SD, McKnight SL. tk Enzyme expression in differentiating muscle cells is regulated through an internal segment of the cellular tk gene. Molecular and Cellular Biology. 4: 1777-84. PMID 6493233 DOI: 10.1128/MCB.4.9.1777  0.349
1984 Merrill GF, Harland RM, Groudine M, McKnight SL. Genetic and physical analysis of the chicken tk gene. Molecular and Cellular Biology. 4: 1769-76. PMID 6092937 DOI: 10.1128/MCB.4.9.1769  0.318
1983 Harland RM, Weintraub H, McKnight SL. Transcription of DNA injected into Xenopus oocytes is influenced by template topology. Nature. 302: 38-43. PMID 6828158 DOI: 10.1038/302038a0  0.344
1983 McKnight SL. Constitutive transcriptional control signals of the herpes simplex virus tk gene. Cold Spring Harbor Symposia On Quantitative Biology. 47: 945-58. PMID 6305594 DOI: 10.1101/Sqb.1983.047.01.108  0.301
1982 McKnight SL. Functional relationships between transcriptional control signals of the thymidine kinase gene of herpes simplex virus. Cell. 31: 355-65. PMID 6297762 DOI: 10.1016/0092-8674(82)90129-5  0.31
1982 Sollner-Webb B, McKnight SL. Accurate transcription of cloned Xenopus rRNA genes by RNA polymerase I: demonstration by S1 nuclease mapping. Nucleic Acids Research. 10: 3391-405. PMID 6285299 DOI: 10.1093/nar/10.11.3391  0.335
1982 McKnight SL, Kingsbury R. Transcriptional control signals of a eukaryotic protein-coding gene. Science (New York, N.Y.). 217: 316-24. PMID 6283634 DOI: 10.1126/Science.6283634  0.338
1981 McKnight SL, Gavis ER, Kingsbury R, Axel R. Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: identification of an upstream control region. Cell. 25: 385-98. PMID 6269744 DOI: 10.1016/0092-8674(81)90057-X  0.381
1980 McKnight SL, Hipskind RA, Reeder R. Ultrastructural analysis of ribosomal gene transcription in vitro. The Journal of Biological Chemistry. 255: 7907-11. PMID 7400153  0.589
1980 Beyer AL, Miller OL, McKnight SL. Ribonucleoprotein structure in nascent hnRNA is nonrandom and sequence-dependent. Cell. 20: 75-84. PMID 6771017 DOI: 10.1016/0092-8674(80)90236-6  0.678
1980 McKnight SL. The nucleotide sequence and transcript map of the herpes simplex virus thymidine kinase gene. Nucleic Acids Research. 8: 5949-64. PMID 6258156 DOI: 10.1093/nar/8.24.5949  0.345
1980 McKnight SL, Gavis ER. Expression of the herpes thymidine kinase gene in Xenopus laevis oocytes: an assay for the study of deletion mutants constructed in vitro. Nucleic Acids Research. 8: 5931-48. PMID 6258155 DOI: 10.1093/nar/8.24.5931  0.349
1980 McKnight SL, Hipskind RA, Reeder R. Ultrastructural analysis of ribosomal gene transcription in vitro Journal of Biological Chemistry. 255: 790-791.  0.581
1979 McKnight SL, Miller OL. Post-replicative nonribosomal transcription units in D. melanogaster embryos. Cell. 17: 551-63. PMID 113103 DOI: 10.1016/0092-8674(79)90263-0  0.624
1978 McKnight SL, Bustin M, Miller OL. Electron microscopic analysis of chromosome metabolism in the Drosophila melanogaster embryo. Cold Spring Harbor Symposia On Quantitative Biology. 42: 741-54. PMID 98268 DOI: 10.1101/Sqb.1978.042.01.075  0.583
1977 Bustin M, Reeder RH, McKnight SL. Immunological cross-reaction between calf and Drosophila histones. The Journal of Biological Chemistry. 252: 3099-101. PMID 856814  0.51
1977 McKnight SL, Miller OL. Electron microscopic analysis of chromatin replication in the cellular blastoderm Drosophila melanogaster embryo. Cell. 12: 795-804. PMID 411576 DOI: 10.1016/0092-8674(77)90278-1  0.613
1976 McKnight SL, Sullivan NL, Miller OL. Visualization of the silk fibroin transcription unit and nascent silk fibroin molecules on polyribosomes of Bombyx mori. Progress in Nucleic Acid Research and Molecular Biology. 19: 313-8. PMID 1019350 DOI: 10.1016/S0079-6603(08)60928-9  0.647
1976 McKnight SL, Miller OL. Ultrastructural patterns of RNA synthesis during early embryogenesis of Drosophila melanogaster. Cell. 8: 305-19. PMID 822943 DOI: 10.1016/0092-8674(76)90014-3  0.646
Low-probability matches (unlikely to be authored by this person)
2013 Kaelin WG, McKnight SL. Influence of metabolism on epigenetics and disease. Cell. 153: 56-69. PMID 23540690 DOI: 10.1016/J.Cell.2013.03.004  0.298
2014 McKnight SL. A hypothetical means of treating or preventing cancer Cancer and Metabolism. 2: 1-1. DOI: 10.1186/2049-3002-2-S1-O7  0.293
1994 Hou J, Schindler U, Henzel WJ, Ho TC, Brasseur M, McKnight SL. An interleukin-4-induced transcription factor: IL-4 Stat. Science (New York, N.Y.). 265: 1701-6. PMID 8085155 DOI: 10.1126/Science.8085155  0.292
2018 Murray DT, Zhou X, Kato M, Xiang S, Tycko R, McKnight SL. Structural characterization of the D290V mutation site in hnRNPA2 low-complexity-domain polymers. Proceedings of the National Academy of Sciences of the United States of America. PMID 30279180 DOI: 10.1073/Pnas.1806174115  0.292
2007 Williams NS, Burgett AW, Atkins AS, Wang X, Harran PG, McKnight SL. Therapeutic anticancer efficacy of a synthetic diazonamide analog in the absence of overt toxicity. Proceedings of the National Academy of Sciences of the United States of America. 104: 2074-9. PMID 17287337 DOI: 10.1073/Pnas.0611340104  0.291
1995 Schindler U, Wu P, Rothe M, Brasseur M, McKnight SL. Components of a Stat recognition code: evidence for two layers of molecular selectivity. Immunity. 2: 689-97. PMID 7796300 DOI: 10.1016/1074-7613(95)90013-6  0.29
1993 McKnight SL, Schibler U. Gene expression and differentiation Editorial overview Current Opinion in Genetics and Development. 3: 201-202. DOI: 10.1016/0959-437X(93)90023-I  0.29
1991 Cao Z, Umek RM, McKnight SL. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes & Development. 5: 1538-52. PMID 1840554 DOI: 10.1101/Gad.5.9.1538  0.289
2010 McKnight SL. On getting there from here. Science (New York, N.Y.). 330: 1338-9. PMID 21127243 DOI: 10.1126/science.1199908  0.288
1995 Yeh WC, McKnight SL. Regulation of adipose maturation and energy homeostasis. Current Opinion in Cell Biology. 7: 885-90. PMID 8608020 DOI: 10.1016/0955-0674(95)80074-3  0.287
1995 Yeh WC, Bierer BE, McKnight SL. Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 11086-90. PMID 7479942 DOI: 10.1073/Pnas.92.24.11086  0.285
1983 Harland RM, Weintraub H, McKnight SL. Transcription of circular and linear DNAs in amphibian oocytes. Cold Spring Harbor Symposia On Quantitative Biology. 47: 958-63. PMID 6305595 DOI: 10.1101/SQB.1983.047.01.109  0.285
1994 de la Brousse FC, Birkenmeier EH, King DS, Rowe LB, McKnight SL. Molecular and genetic characterization of GABP beta. Genes & Development. 8: 1853-65. PMID 7958862 DOI: 10.1101/Gad.8.15.1853  0.278
1987 Tufaro F, Snider MD, McKnight SL. Identification and characterization of a mouse cell mutant defective in the intracellular transport of glycoproteins. The Journal of Cell Biology. 105: 647-57. PMID 3040769 DOI: 10.1083/Jcb.105.2.647  0.274
1984 McKnight SL, Kingsbury RC, Spence A, Smith M. The distal transcription signals of the herpesvirus tk gene share a common hexanucleotide control sequence. Cell. 37: 253-62. PMID 6233005 DOI: 10.1016/0092-8674(84)90321-0  0.265
2012 McKnight SL. Pure genes, pure genius. Cell. 150: 1100-2. PMID 22980972 DOI: 10.1016/j.cell.2012.08.022  0.259
1995 Hou J, Schindler U, Henzel WJ, Wong SC, McKnight SL. Identification and purification of human Stat proteins activated in response to interleukin-2. Immunity. 2: 321-9. PMID 7719937 DOI: 10.1016/1074-7613(95)90140-X  0.254
1982 McKnight SL, Chao M, Sweet RW, Silverstein S, Axel R. The structure and function of a eukaryotic promoter. Princess Takamatsu Symposia. 12: 73-85. PMID 6300029  0.251
2014 Minna JD, Gazdar A, Augustyn A, Britt R, Carstens R, Dospoy P, Gao B, Girard L, Hight S, Huffman K, Larsen J, Peyton M, Shao C, Mangelsdorf D, Brekken R, ... ... McKnight S, et al. Abstract IA21: Developing a new functional classification of lung cancer based on tumor acquired vulnerabilities. Clinical Cancer Research. 20: IA21-IA21. DOI: 10.1158/1078-0432.14Aacriaslc-Ia21  0.251
2005 Wu X, Alexander PB, He Y, Kikkawa M, Vogel PD, McKnight SL. Mammalian sprouty proteins assemble into large monodisperse particles having the properties of intracellular nanobatteries. Proceedings of the National Academy of Sciences of the United States of America. 102: 14058-62. PMID 16172380 DOI: 10.1073/Pnas.0506714102  0.249
2006 Franken P, Dudley CA, Estill SJ, Barakat M, Thomason R, O'Hara BF, McKnight SL. NPAS2 as a transcriptional regulator of non-rapid eye movement sleep: genotype and sex interactions. Proceedings of the National Academy of Sciences of the United States of America. 103: 7118-23. PMID 16636276 DOI: 10.1073/Pnas.0602006103  0.244
2003 Gilles-Gonzalez M, Dioum EM, Rutter JR, Gonzalez G, McKnight SL, Tuckerman JR. Signal transduction by PAS-domain containing heme-based sensors: an overview Journal of Inorganic Biochemistry. 96: 15. DOI: 10.1016/S0162-0134(03)80428-2  0.244
1998 McKnight SL. WAT-free mice: diabetes without obesity Genes & Development. 12: 3145-8. PMID 9784488 DOI: 10.1101/Gad.12.20.3145  0.23
2002 Bruick RK, McKnight SL. Transcription. Oxygen sensing gets a second wind. Science (New York, N.Y.). 295: 807-8. PMID 11823627 DOI: 10.1126/science.1069825  0.226
2004 Harrison SC, Alberts B, Ehrenfeld E, Enquist L, Fineberg H, McKnight SL, Moss B, O'Donnell M, Ploegh H, Schmid SL, Walter KP, Theriot J. Discovery of antivirals against smallpox. Proceedings of the National Academy of Sciences of the United States of America. 101: 11178-92. PMID 15249657 DOI: 10.1073/Pnas.0403600101  0.216
2022 Kato M, Zhou X, McKnight SL. How do protein domains of low sequence complexity work? Rna (New York, N.Y.). 28: 3-15. PMID 34670847 DOI: 10.1261/rna.078990.121  0.213
1997 McKnight SL. Gatekeepers of organ growth. Proceedings of the National Academy of Sciences of the United States of America. 94: 12249-50. PMID 9356433 DOI: 10.1073/pnas.94.23.12249  0.212
2002 Gallagher LA, McKnight SL, Kuznetsova MS, Pesci EC, Manoil C. Functions required for extracellular quinolone signaling by Pseudomonas aeruginosa. Journal of Bacteriology. 184: 6472-80. PMID 12426334 DOI: 10.1128/Jb.184.23.6472-6480.2002  0.194
2008 Coleman JP, Hudson LL, McKnight SL, Farrow JM, Calfee MW, Lindsey CA, Pesci EC. Pseudomonas aeruginosa PqsA is an anthranilate-coenzyme A ligase. Journal of Bacteriology. 190: 1247-55. PMID 18083812 DOI: 10.1128/Jb.01140-07  0.192
2021 Kato M, McKnight SL. The low-complexity domain of the FUS RNA binding protein self-assembles via the mutually exclusive use of two distinct cross-β cores. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34654750 DOI: 10.1073/pnas.2114412118  0.187
1998 McKnight S, Schibler U. Editorial overview: The devil is in the detail Current Opinion in Genetics and Development. 8: 511-513. DOI: 10.1016/S0959-437X(98)80003-8  0.183
1986 McKnight SL. Phage a: a genetic switch. Science (New York, N.Y.). 233: 1435-6. PMID 17830742 DOI: 10.1126/science.233.4771.1435-a  0.183
2001 Bruick RK, McKnight SL. Building better vasculature. Genes & Development. 15: 2497-502. PMID 11581154 DOI: 10.1101/gad.931601  0.183
2003 Bennett MJ, McKnight SL, Coleman JP. Cloning and characterization of the NAD-dependent 7alpha-Hydroxysteroid dehydrogenase from Bacteroides fragilis. Current Microbiology. 47: 475-84. PMID 14756531  0.182
1991 McKnight SL. Discovery of a transcription factor that catalyzes terminal cell differentiation. Harvey Lectures. 87: 57-68. PMID 1670549  0.179
2000 McKnight SL, Iglewski BH, Pesci EC. The Pseudomonas quinolone signal regulates rhl quorum sensing in Pseudomonas aeruginosa. Journal of Bacteriology. 182: 2702-8. PMID 10781536 DOI: 10.1128/Jb.182.10.2702-2708.2000  0.165
1982 McKnight SL, Chao M, Sweet RW, Silverstein S, Axel R. Transcriptional control of transformed genes. Oncodevelopmental Biology and Medicine : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 4: 81-95. PMID 6891055  0.16
2022 Zhou X, Sumrow L, Tashiro K, Sutherland L, Liu D, Qin T, Kato M, Liszczak G, McKnight SL. Mutations linked to neurological disease enhance self-association of low-complexity protein sequences. Science (New York, N.Y.). 377: eabn5582. PMID 35771920 DOI: 10.1126/science.abn5582  0.155
2021 Zhou X, Lin Y, Kato M, Mori E, Liszczak G, Sutherland L, Sysoev VO, Murray DT, Tycko R, McKnight SL. Transiently structured head domains control intermediate filament assembly. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33593918 DOI: 10.1073/pnas.2022121118  0.15
2023 Zhou X, Kato M, McKnight SL. How do disordered head domains assist in the assembly of intermediate filaments? Current Opinion in Cell Biology. 85: 102262. PMID 37871501 DOI: 10.1016/j.ceb.2023.102262  0.145
1992 Mahoney CW, Shuman J, McKnight SL, Chen HC, Huang KP. Phosphorylation of CCAAT-enhancer binding protein by protein kinase C attenuates site-selective DNA binding. The Journal of Biological Chemistry. 267: 19396-403. PMID 1527059  0.138
2023 Gu J, Zhou X, Sutherland L, Kato M, Jaczynska K, Rizo J, McKnight SL. Oxidative regulation of TDP-43 self-association by a β-to-α conformational switch. Biorxiv : the Preprint Server For Biology. PMID 37693418 DOI: 10.1101/2023.08.29.555361  0.137
2023 Gu J, Zhou X, Sutherland L, Kato M, Jaczynska K, Rizo J, McKnight SL. Oxidative regulation of TDP-43 self-association by a β-to-α conformational switch. Proceedings of the National Academy of Sciences of the United States of America. 120: e2311416120. PMID 37782781 DOI: 10.1073/pnas.2311416120  0.125
2019 McKnight SL. Passing Through. Trends in Biochemical Sciences. PMID 31629612 DOI: 10.1016/j.tibs.2019.09.004  0.107
2002 Collier DN, Anderson L, McKnight SL, Noah TL, Knowles M, Boucher R, Schwab U, Gilligan P, Pesci EC. A bacterial cell to cell signal in the lungs of cystic fibrosis patients. Fems Microbiology Letters. 215: 41-6. PMID 12393198 DOI: 10.1111/J.1574-6968.2002.Tb11367.X  0.086
2020 McKnight S, Hack N. Toxin-Induced Parkinsonism. Neurologic Clinics. 38: 853-865. PMID 33040865 DOI: 10.1016/j.ncl.2020.08.003  0.066
1998 McKnight SL. WAT-free mice: diabetes without obesity. Genes & Development. 12: 3145-48. PMID 9867473  0.036
2009 McKnight SL. Unconventional wisdom. Cell. 138: 817-9. PMID 19737508 DOI: 10.1016/j.cell.2009.08.016  0.032
2023 McKnight S, Spradling A. Donald D. Brown (1931-2023). Science (New York, N.Y.). 381: 128. PMID 37440618 DOI: 10.1126/science.adj2815  0.029
2002 Nichol S, May K, Lees E, Hansen T, Heuler N, McKnight SL, Borkovetz R. Are "ecocemeteries" a viable option? Pros and cons [2] Landscape Architecture. 92: 9-12.  0.019
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