Bruce A Edgar - Publications

1993-2009 Fred Hutchinson Cancer Research Center, Seattle, WA, United States 
 2009-2016 Ruprecht-Karls-Universität Heidelberg, Heidelberg, Baden-Württemberg, Germany 
 2016- Huntsman Cancer Institute University of Utah, Salt Lake City, UT 
cell growth and proliferation in the fruit fly, Drosophila melanogaster

121 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Tauc HM, Rodriguez-Fernandez IA, Hackney JA, Pawlak M, Ronnen Oron T, Korzelius J, Moussa HF, Chaudhuri S, Modrusan Z, Edgar BA, Jasper H. Age-related changes in Polycomb gene regulation disrupt lineage fidelity in intestinal stem cells. Elife. 10. PMID 33724181 DOI: 10.7554/eLife.62250  0.64
2021 Zhang P, Katzaroff AJ, Buttitta LA, Ma Y, Jiang H, Nickerson DW, Øvrebø JI, Edgar BA. The Krüppel-like factor Cabut has cell cycle regulatory properties similar to E2F1. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33558234 DOI: 10.1073/pnas.2015675118  1
2020 Zhang P, Edgar BA. Lipoic acid and autophagy: new insights into stem cell aging. Embo Reports. e202051175. PMID 32715610 DOI: 10.15252/embr.202051175  0.64
2020 Ahmed SMH, Maldera JA, Krunic D, Paiva-Silva GO, Pénalva C, Teleman AA, Edgar BA. Fitness trade-offs incurred by ovary-to-gut steroid signalling in Drosophila. Nature. PMID 32641829 DOI: 10.1038/s41586-020-2462-y  0.64
2019 Patel PH, Pénalva C, Kardorff M, Roca M, Pavlović B, Thiel A, Teleman AA, Edgar BA. Damage sensing by a Nox-Ask1-MKK3-p38 signaling pathway mediates regeneration in the adult Drosophila midgut. Nature Communications. 10: 4365. PMID 31554796 DOI: 10.1038/s41467-019-12336-w  0.96
2019 Zhang P, Holowatyj AN, Ulrich CM, Edgar BA. Tumor suppressive autophagy in intestinal stem cells controls gut homeostasis. Autophagy. 1-3. PMID 31213134 DOI: 10.1080/15548627.2019.1633863  0.64
2019 Zhang P, Holowatyj AN, Roy T, Pronovost SM, Marchetti M, Liu H, Ulrich CM, Edgar BA. An SH3PX1-Dependent Endocytosis-Autophagy Network Restrains Intestinal Stem Cell Proliferation by Counteracting EGFR-ERK Signaling. Developmental Cell. PMID 31006650 DOI: 10.1016/j.devcel.2019.03.029  0.64
2018 Øvrebø JI, Edgar BA. Polyploidy in tissue homeostasis and regeneration. Development (Cambridge, England). 145. PMID 30021843 DOI: 10.1242/dev.156034  0.64
2017 Edgar BA, Grewal SS. Longer life through an odd Pol enzyme. Nature. 552: 182-183. PMID 32080456 DOI: 10.1038/d41586-017-07435-x  0.32
2017 Edgar BA, Grewal SS. Longer life through an odd Pol enzyme. Nature. 552: 182-183. PMID 29239369 DOI: 10.1038/d41586-017-07435-x  0.32
2017 Zhang P, Pei C, Wang X, Xiang J, Sun BF, Cheng Y, Qi X, Marchetti M, Xu JW, Sun YP, Edgar BA, Yuan Z. A Balance of Yki/Sd Activator and E2F1/Sd Repressor Complexes Controls Cell Survival and Affects Organ Size. Developmental Cell. 43: 603-617.e5. PMID 29207260 DOI: 10.1016/j.devcel.2017.10.033  0.64
2017 Xiang J, Bandura J, Zhang P, Jin Y, Reuter H, Edgar BA. EGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration. Nature Communications. 8: 15125. PMID 28485389 DOI: 10.1038/ncomms15125  0.64
2017 Jin Y, Patel PH, Kohlmaier A, Pavlovic B, Zhang C, Edgar BA. Intestinal Stem Cell Pool Regulation in Drosophila. Stem Cell Reports. PMID 28479306 DOI: 10.1016/j.stemcr.2017.04.002  0.96
2016 Zielke N, van Straaten M, Bohlen J, Edgar BA. Using the Fly-FUCCI System for the Live Analysis of Cell Cycle Dynamics in Cultured Drosophila Cells. Methods in Molecular Biology (Clifton, N.J.). 1342: 305-20. PMID 26254933 DOI: 10.1007/978-1-4939-2957-3_19  0.32
2015 Jin Y, Ha N, Forés M, Xiang J, Gläßer C, Maldera J, Jiménez G, Edgar BA. EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated Genes. Plos Genetics. 11: e1005634. PMID 26683696 DOI: 10.1371/journal.pgen.1005634  0.32
2015 Patel PH, Dutta D, Edgar BA. Niche appropriation by Drosophila intestinal stem cell tumours. Nature Cell Biology. 17: 1182-92. PMID 26237646 DOI: 10.1038/ncb3214  1
2015 Dutta D, Buchon N, Xiang J, Edgar BA. Regional Cell Specific RNA Expression Profiling of FACS Isolated Drosophila Intestinal Cell Populations. Current Protocols in Stem Cell Biology. 34: 2F.2.1-2F.2.14. PMID 26237570 DOI: 10.1002/9780470151808.sc02f02s34  1
2015 Icreverzi A, de la Cruz AF, Walker DW, Edgar BA. Changes in neuronal CycD/Cdk4 activity affect aging, neurodegeneration, and oxidative stress. Aging Cell. 14: 896-906. PMID 26219626 DOI: 10.1111/acel.12376  1
2015 Dutta D, Dobson AJ, Houtz PL, Gläßer C, Revah J, Korzelius J, Patel PH, Edgar BA, Buchon N. Regional Cell-Specific Transcriptome Mapping Reveals Regulatory Complexity in the Adult Drosophila Midgut. Cell Reports. PMID 26146076 DOI: 10.1016/j.celrep.2015.06.009  1
2015 Zielke N, Edgar BA. FUCCI sensors: powerful new tools for analysis of cell proliferation. Wiley Interdisciplinary Reviews. Developmental Biology. PMID 25827130 DOI: 10.1002/wdev.189  1
2015 Zhou J, Florescu S, Boettcher AL, Luo L, Dutta D, Kerr G, Cai Y, Edgar BA, Boutros M. Dpp/Gbb signaling is required for normal intestinal regeneration during infection. Developmental Biology. 399: 189-203. PMID 25553980 DOI: 10.1016/j.ydbio.2014.12.017  1
2015 Kohlmaier A, Fassnacht C, Jin Y, Reuter H, Begum J, Dutta D, Edgar BA. Src kinase function controls progenitor cell pools during regeneration and tumor onset in the Drosophila intestine. Oncogene. 34: 2371-84. PMID 24975577 DOI: 10.1038/onc.2014.163  1
2014 Korzelius J, Naumann SK, Loza-Coll MA, Chan JS, Dutta D, Oberheim J, Gläßer C, Southall TD, Brand AH, Jones DL, Edgar BA. Escargot maintains stemness and suppresses differentiation in Drosophila intestinal stem cells. The Embo Journal. 33: 2967-82. PMID 25298397 DOI: 10.15252/Embj.201489072  1
2014 Knop M, Edgar BA. Tracking protein turnover and degradation by microscopy: photo-switchable versus time-encoded fluorescent proteins. Open Biology. 4: 140002. PMID 24740984 DOI: 10.1098/Rsob.140002  1
2014 Zielke N, Korzelius J, van Straaten M, Bender K, Schuhknecht GF, Dutta D, Xiang J, Edgar BA. Fly-FUCCI: A versatile tool for studying cell proliferation in complex tissues. Cell Reports. 7: 588-98. PMID 24726363 DOI: 10.1016/j.celrep.2014.03.020  1
2014 Patel PH, Edgar BA. Tissue design: how Drosophila tumors remodel their neighborhood. Seminars in Cell & Developmental Biology. 28: 86-95. PMID 24685612 DOI: 10.1016/j.semcdb.2014.03.012  1
2014 O'Keefe DD, Thomas S, Edgar BA, Buttitta L. Temporal regulation of Dpp signaling output in the Drosophila wing. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 243: 818-32. PMID 24591046 DOI: 10.1002/Dvdy.24122  1
2014 Edgar BA, Zielke N, Gutierrez C. Endocycles: a recurrent evolutionary innovation for post-mitotic cell growth. Nature Reviews. Molecular Cell Biology. 15: 197-210. PMID 24556841 DOI: 10.1038/nrm3756  1
2014 Song M, Zhang Y, Katzaroff AJ, Edgar BA, Buttitta L. Hunting complex differential gene interaction patterns across molecular contexts. Nucleic Acids Research. 42: e57. PMID 24482443 DOI: 10.1093/Nar/Gku086  1
2013 Dutta D, Xiang J, Edgar BA. RNA expression profiling from FACS-isolated cells of the Drosophila intestine. Current Protocols in Stem Cell Biology. 27: Unit 2F.2.. PMID 24510286 DOI: 10.1002/9780470151808.sc02f02s27  1
2013 Patel PH, Maldera JA, Edgar BA. Stimulating cROSstalk between commensal bacteria and intestinal stem cells. The Embo Journal. 32: 3009-10. PMID 24193404 DOI: 10.1038/emboj.2013.244  1
2013 Kuo Y, Ren S, Lao U, Edgar BA, Wang T. Suppression of polyglutamine protein toxicity by co-expression of a heat-shock protein 40 and a heat-shock protein 110. Cell Death & Disease. 4: e833. PMID 24091676 DOI: 10.1038/Cddis.2013.351  1
2013 Bandura JL, Jiang H, Nickerson DW, Edgar BA. The molecular chaperone Hsp90 is required for cell cycle exit in Drosophila melanogaster. Plos Genetics. 9: e1003835. PMID 24086162 DOI: 10.1371/Journal.Pgen.1003835  1
2013 Doumpas N, Ruiz-Romero M, Blanco E, Edgar B, Corominas M, Teleman AA. Brk regulates wing disc growth in part via repression of Myc expression. Embo Reports. 14: 261-8. PMID 23337628 DOI: 10.1038/embor.2013.1  1
2013 Zielke N, Edgar BA, DePamphilis ML. Endoreplication. Cold Spring Harbor Perspectives in Biology. 5: a012948. PMID 23284048 DOI: 10.1101/cshperspect.a012948  1
2012 Brown HL, Kaun KR, Edgar BA. The small GTPase Rheb affects central brain neuronal morphology and memory formation in Drosophila. Plos One. 7: e44888. PMID 23028662 DOI: 10.1371/journal.pone.0044888  1
2012 O'Keefe DD, Thomas SR, Bolin K, Griggs E, Edgar BA, Buttitta LA. Combinatorial control of temporal gene expression in the Drosophila wing by enhancers and core promoters. Bmc Genomics. 13: 498. PMID 22992320 DOI: 10.1186/1471-2164-13-498  1
2012 O'Keefe DD, Gonzalez-Niño E, Edgar BA, Curtiss J. Discontinuities in Rap1 activity determine epithelial cell morphology within the developing wing of Drosophila. Developmental Biology. 369: 223-34. PMID 22776378 DOI: 10.1016/J.Ydbio.2012.06.024  1
2012 Jiang H, Edgar BA. Intestinal stem cell function in Drosophila and mice. Current Opinion in Genetics & Development. 22: 354-60. PMID 22608824 DOI: 10.1016/J.Gde.2012.04.002  1
2012 Edgar BA. Intestinal stem cells: no longer immortal but ever so clever.... The Embo Journal. 31: 2441-3. PMID 22580826 DOI: 10.1038/emboj.2012.133  1
2012 Wang T, Blumhagen R, Lao U, Kuo Y, Edgar BA. LST8 regulates cell growth via target-of-rapamycin complex 2 (TORC2). Molecular and Cellular Biology. 32: 2203-13. PMID 22493059 DOI: 10.1128/Mcb.06474-11  1
2012 Icreverzi A, de la Cruz AF, Van Voorhies WA, Edgar BA. Drosophila cyclin D/Cdk4 regulates mitochondrial biogenesis and aging and sensitizes animals to hypoxic stress. Cell Cycle (Georgetown, Tex.). 11: 554-68. PMID 22293404 DOI: 10.4161/cc.11.3.19062  1
2011 Zielke N, Kim KJ, Tran V, Shibutani ST, Bravo MJ, Nagarajan S, van Straaten M, Woods B, von Dassow G, Rottig C, Lehner CF, Grewal SS, Duronio RJ, Edgar BA. Control of Drosophila endocycles by E2F and CRL4(CDT2). Nature. 480: 123-7. PMID 22037307 DOI: 10.1038/Nature10579  1
2011 Jiang H, Edgar BA. Intestinal stem cells in the adult Drosophila midgut. Experimental Cell Research. 317: 2780-8. PMID 21856297 DOI: 10.1016/J.Yexcr.2011.07.020  1
2011 Jiang H, Grenley MO, Bravo MJ, Blumhagen RZ, Edgar BA. EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila. Cell Stem Cell. 8: 84-95. PMID 21167805 DOI: 10.1016/J.Stem.2010.11.026  1
2011 O'Keefe DD, Edgar BA, Saucedo LJ. EndoGI modulates Notch signaling and axon guidance in Drosophila. Mechanisms of Development. 128: 59-70. PMID 21055464 DOI: 10.1016/j.mod.2010.10.001  1
2010 Shaw RL, Kohlmaier A, Polesello C, Veelken C, Edgar BA, Tapon N. The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration. Development (Cambridge, England). 137: 4147-58. PMID 21068063 DOI: 10.1242/Jcs.084137  1
2010 Buttitta LA, Katzaroff AJ, Edgar BA. A robust cell cycle control mechanism limits E2F-induced proliferation of terminally differentiated cells in vivo. The Journal of Cell Biology. 189: 981-96. PMID 20548101 DOI: 10.1083/jcb.200910006  1
2010 Li L, Edgar BA, Grewal SS. Nutritional control of gene expression in Drosophila larvae via TOR, Myc and a novel cis-regulatory element. Bmc Cell Biology. 11: 7. PMID 20089194 DOI: 10.1186/1471-2121-11-7  1
2010 Wang T, Edgar BA. TOR signaling and cell death Enzymes. 28: 217-244. DOI: 10.1016/S1874-6047(10)28011-3  1
2009 Joe Song M, Hong CC, Zhang Y, Buttitta L, Edgar BA. Comparative Generalized Logic Modeling Reveals Differential Gene Interactions during Cell Cycle Exit in Drosophila Wing Development. Gi-Edition. Proceedings. 157: 143-152. PMID 25285063  1
2009 Wang T, Lao U, Edgar BA. TOR-mediated autophagy regulates cell death in Drosophila neurodegenerative disease. The Journal of Cell Biology. 186: 703-11. PMID 19720874 DOI: 10.1083/Jcb.200904090  1
2009 Edgar BA, Kim KJ. Cell biology. Sizing up the cell. Science (New York, N.Y.). 325: 158-9. PMID 19589991 DOI: 10.1126/science.1177203  1
2009 O'Keefe DD, Gonzalez-Niño E, Burnett M, Dylla L, Lambeth SM, Licon E, Amesoli C, Edgar BA, Curtiss J. Rap1 maintains adhesion between cells to affect Egfr signaling and planar cell polarity in Drosophila. Developmental Biology. 333: 143-60. PMID 19576205 DOI: 10.1016/J.Ydbio.2009.06.032  1
2009 Jiang H, Patel PH, Kohlmaier A, Grenley MO, McEwen DG, Edgar BA. Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut. Cell. 137: 1343-55. PMID 19563763 DOI: 10.1016/J.Cell.2009.05.014  1
2009 Jiang H, Edgar BA. EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors. Development (Cambridge, England). 136: 483-93. PMID 19141677 DOI: 10.1242/Dev.026955  1
2008 Shibutani ST, de la Cruz AF, Tran V, Turbyfill WJ, Reis T, Edgar BA, Duronio RJ. Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase. Developmental Cell. 15: 890-900. PMID 19081076 DOI: 10.1016/J.Devcel.2008.10.003  1
2008 Kohlmaier A, Edgar BA. Proliferative control in Drosophila stem cells. Current Opinion in Cell Biology. 20: 699-706. PMID 18996190 DOI: 10.1016/  1
2008 de la Cruz AF, Edgar BA. Flow cytometric analysis of Drosophila cells. Methods in Molecular Biology (Clifton, N.J.). 420: 373-89. PMID 18641961 DOI: 10.1007/978-1-59745-583-1_24  1
2008 Bandura JL, Edgar BA. Yorkie and Scalloped: partners in growth activation. Developmental Cell. 14: 315-6. PMID 18331708 DOI: 10.1016/j.devcel.2008.02.010  1
2008 Oren-Giladi P, Krieger O, Edgar BA, Chamovitz DA, Segal D. Cop9 signalosome subunit 8 (CSN8) is essential for Drosophila development. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 13: 221-31. PMID 18298797 DOI: 10.1111/J.1365-2443.2008.01164.X  1
2007 Grewal SS, Evans JR, Edgar BA. Drosophila TIF-IA is required for ribosome synthesis and cell growth and is regulated by the TOR pathway. The Journal of Cell Biology. 179: 1105-13. PMID 18086911 DOI: 10.1083/jcb.200709044  1
2007 Buttitta LA, Edgar BA. Mechanisms controlling cell cycle exit upon terminal differentiation. Current Opinion in Cell Biology. 19: 697-704. PMID 18035529 DOI: 10.1016/  1
2007 Buttitta LA, Edgar BA. How size is controlled: from Hippos to Yorkies. Nature Cell Biology. 9: 1225-7. PMID 17975546 DOI: 10.1038/ncb1107-1225  1
2007 O'Keefe DD, Prober DA, Moyle PS, Rickoll WL, Edgar BA. Egfr/Ras signaling regulates DE-cadherin/Shotgun localization to control vein morphogenesis in the Drosophila wing. Developmental Biology. 311: 25-39. PMID 17888420 DOI: 10.1016/J.Ydbio.2007.08.003  1
2007 Saucedo LJ, Edgar BA. Filling out the Hippo pathway. Nature Reviews. Molecular Cell Biology. 8: 613-21. PMID 17622252 DOI: 10.1038/nrm2221  1
2007 Oron E, Tuller T, Li L, Rozovsky N, Yekutieli D, Rencus-Lazar S, Segal D, Chor B, Edgar BA, Chamovitz DA. Genomic analysis of COP9 signalosome function in Drosophila melanogaster reveals a role in temporal regulation of gene expression. Molecular Systems Biology. 3: 108. PMID 17486136 DOI: 10.1038/Msb4100150  1
2007 Buttitta LA, Katzaroff AJ, Perez CL, de la Cruz A, Edgar BA. A double-assurance mechanism controls cell cycle exit upon terminal differentiation in Drosophila. Developmental Cell. 12: 631-43. PMID 17419999 DOI: 10.1016/j.devcel.2007.02.020  1
2007 Hall DJ, Grewal SS, de la Cruz AF, Edgar BA. Rheb-TOR signaling promotes protein synthesis, but not glucose or amino acid import, in Drosophila. Bmc Biology. 5: 10. PMID 17371599 DOI: 10.1186/1741-7007-5-10  1
2006 Edgar BA. How flies get their size: genetics meets physiology. Nature Reviews. Genetics. 7: 907-16. PMID 17139322 DOI: 10.1038/nrg1989  1
2006 Datar SA, Galloni M, de la Cruz A, Marti M, Edgar BA, Frei C. Mammalian cyclin D1/Cdk4 complexes induce cell growth in Drosophila. Cell Cycle (Georgetown, Tex.). 5: 647-52. PMID 16582602 DOI: 10.4161/Cc.5.6.2573  1
2006 Edgar BA. From cell structure to transcription: Hippo forges a new path. Cell. 124: 267-73. PMID 16439203 DOI: 10.1016/j.cell.2006.01.005  1
2005 Orian A, Grewal SS, Knoepfler PS, Edgar BA, Parkhurst SM, Eisenman RN. Genomic binding and transcriptional regulation by the Drosophila Myc and Mnt transcription factors. Cold Spring Harbor Symposia On Quantitative Biology. 70: 299-307. PMID 16869766 DOI: 10.1101/Sqb.2005.70.019  1
2005 Loo LW, Secombe J, Little JT, Carlos LS, Yost C, Cheng PF, Flynn EM, Edgar BA, Eisenman RN. The transcriptional repressor dMnt is a regulator of growth in Drosophila melanogaster. Molecular and Cellular Biology. 25: 7078-91. PMID 16055719 DOI: 10.1128/Mcb.25.16.7078-7091.2005  1
2005 Grewal SS, Li L, Orian A, Eisenman RN, Edgar BA. Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development. Nature Cell Biology. 7: 295-302. PMID 15723055 DOI: 10.1038/Ncb1223  1
2004 Emmerich J, Meyer CA, de la Cruz AF, Edgar BA, Lehner CF. Cyclin D does not provide essential Cdk4-independent functions in Drosophila. Genetics. 168: 867-75. PMID 15514060 DOI: 10.1534/genetics.104.027417  1
2004 Pierce SB, Yost C, Britton JS, Loo LW, Flynn EM, Edgar BA, Eisenman RN. dMyc is required for larval growth and endoreplication in Drosophila. Development (Cambridge, England). 131: 2317-27. PMID 15128666 DOI: 10.1242/Dev.01108  1
2004 Reis T, Edgar BA. Negative regulation of dE2F1 by cyclin-dependent kinases controls cell cycle timing. Cell. 117: 253-64. PMID 15084262 DOI: 10.1016/S0092-8674(04)00247-8  1
2004 Frei C, Edgar BA. Drosophila cyclin D/Cdk4 requires Hif-1 prolyl hydroxylase to drive cell growth. Developmental Cell. 6: 241-51. PMID 14960278 DOI: 10.1016/S1534-5807(03)00409-X  1
2003 Zhang Y, Gao X, Saucedo LJ, Ru B, Edgar BA, Pan D. Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins. Nature Cell Biology. 5: 578-81. PMID 12771962 DOI: 10.1038/ncb999  1
2003 Saucedo LJ, Gao X, Chiarelli DA, Li L, Pan D, Edgar BA. Rheb promotes cell growth as a component of the insulin/TOR signalling network. Nature Cell Biology. 5: 566-71. PMID 12766776 DOI: 10.1038/ncb996  1
2003 Grewal SS, Edgar BA. Controlling cell division in yeast and animals: does size matter? Journal of Biology. 2: 5. PMID 12733996 DOI: 10.1186/1475-4924-2-5  1
2003 Orian A, van Steensel B, Delrow J, Bussemaker HJ, Li L, Sawado T, Williams E, Loo LW, Cowley SM, Yost C, Pierce S, Edgar BA, Parkhurst SM, Eisenman RN. Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Genes & Development. 17: 1101-14. PMID 12695332 DOI: 10.1101/Gad.1066903  1
2002 Prober DA, Edgar BA. Interactions between Ras1, dMyc, and dPI3K signaling in the developing Drosophila wing. Genes & Development. 16: 2286-99. PMID 12208851 DOI: 10.1101/Gad.991102  1
2002 Saucedo LJ, Edgar BA. Why size matters: altering cell size. Current Opinion in Genetics & Development. 12: 565-71. PMID 12200162 DOI: 10.1016/S0959-437X(02)00341-6  1
2002 Martín-Castellanos C, Edgar BA. A characterization of the effects of Dpp signaling on cell growth and proliferation in the Drosophila wing. Development (Cambridge, England). 129: 1003-13. PMID 11861483  1
2002 Britton JS, Lockwood WK, Li L, Cohen SM, Edgar BA. Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions. Developmental Cell. 2: 239-49. PMID 11832249 DOI: 10.1016/S1534-5807(02)00117-X  1
2002 Frank DJ, Edgar BA, Roth MB. The Drosophila melanogaster gene brain tumor negatively regulates cell growth and ribosomal RNA synthesis. Development (Cambridge, England). 129: 399-407. PMID 11807032  1
2001 Edgar BA, Britton J, de la Cruz AF, Johnston LA, Lehman D, Martin-Castellanos C, Prober D. Pattern- and growth-linked cell cycles in Drosophila development. Novartis Foundation Symposium. 237: 3-12; discussion 12-. PMID 11444048 DOI: 10.1002/0470846666.Ch2  1
2001 Edgar BA, Orr-Weaver TL. Endoreplication cell cycles: more for less. Cell. 105: 297-306. PMID 11348589 DOI: 10.1016/S0092-8674(01)00334-8  1
2001 Prober DA, Edgar BA. Growth regulation by oncogenes--new insights from model organisms. Current Opinion in Genetics & Development. 11: 19-26. PMID 11163146 DOI: 10.1016/S0959-437X(00)00151-9  1
2000 Datar SA, Jacobs HW, de la Cruz AF, Lehner CF, Edgar BA. The Drosophila cyclin D-Cdk4 complex promotes cellular growth. The Embo Journal. 19: 4543-54. PMID 10970848 DOI: 10.1093/emboj/19.17.4543  1
2000 Meyer CA, Jacobs HW, Datar SA, Du W, Edgar BA, Lehner CF. Drosophila Cdk4 is required for normal growth and is dispensable for cell cycle progression. The Embo Journal. 19: 4533-42. PMID 10970847 DOI: 10.1093/emboj/19.17.4533  1
2000 Prober DA, Edgar BA. Ras1 promotes cellular growth in the Drosophila wing. Cell. 100: 435-46. PMID 10693760 DOI: 10.1016/S0092-8674(00)80679-0  1
1999 Edgar BA. From small flies come big discoveries about size control. Nature Cell Biology. 1: E191-3. PMID 10587651 DOI: 10.1038/70217  1
1999 Johnston LA, Prober DA, Edgar BA, Eisenman RN, Gallant P. Drosophila myc regulates cellular growth during development. Cell. 98: 779-90. PMID 10499795 DOI: 10.1016/S0092-8674(00)81512-3  1
1999 Migeon JC, Garfinkel MS, Edgar BA. Cloning and characterization of peter pan, a novel Drosophila gene required for larval growth. Molecular Biology of the Cell. 10: 1733-44. PMID 10359593 DOI: 10.1091/Mbc.10.6.1733  1
1999 Galloni M, Edgar BA. Cell-autonomous and non-autonomous growth-defective mutants of Drosophila melanogaster. Development (Cambridge, England). 126: 2365-75. PMID 10225996  1
1999 Lehman DA, Patterson B, Johnston LA, Balzer T, Britton JS, Saint R, Edgar BA. Cis-regulatory elements of the mitotic regulator, string/Cdc25. Development (Cambridge, England). 126: 1793-803. PMID 10101114  1
1999 Edgar BA. Cell cycle control during the development of the fruit fly, Drosophila Kidney International. 56: 1190.  1
1998 Neufeld TP, Edgar BA. Connections between growth and the cell cycle. Current Opinion in Cell Biology. 10: 784-90. PMID 9914170 DOI: 10.1016/S0955-0674(98)80122-1  1
1998 Johnston LA, Edgar BA. Wingless and Notch regulate cell-cycle arrest in the developing Drosophila wing. Nature. 394: 82-4. PMID 9665132 DOI: 10.1038/27925  1
1998 Neufeld TP, de la Cruz AF, Johnston LA, Edgar BA. Coordination of growth and cell division in the Drosophila wing. Cell. 93: 1183-93. PMID 9657151 DOI: 10.1016/S0092-8674(00)81462-2  1
1998 Britton JS, Edgar BA. Environmental control of the cell cycle in Drosophila: nutrition activates mitotic and endoreplicative cells by distinct mechanisms. Development (Cambridge, England). 125: 2149-58. PMID 9570778  1
1996 Edgar BA, Lehner CF. Developmental control of cell cycle regulators: a fly's perspective. Science (New York, N.Y.). 274: 1646-52. PMID 8939845 DOI: 10.1126/science.274.5293.1646  1
1996 Edgar BA, Datar SA. Zygotic degradation of two maternal Cdc25 mRNAs terminates Drosophila's early cell cycle program. Genes & Development. 10: 1966-77. PMID 8756353 DOI: 10.1101/Gad.10.15.1966  1
1995 Edgar B. Diversification of cell cycle controls in developing embryos. Current Opinion in Cell Biology. 7: 815-24. PMID 8608012 DOI: 10.1016/0955-0674(95)80065-4  1
1995 Campbell SD, Sprenger F, Edgar BA, O'Farrell PH. Drosophila Wee1 kinase rescues fission yeast from mitotic catastrophe and phosphorylates Drosophila Cdc2 in vitro. Molecular Biology of the Cell. 6: 1333-47. PMID 8573790  1
1994 Edwards KA, Montague RA, Shepard S, Edgar BA, Erikson RL, Kiehart DP. Identification of Drosophila cytoskeletal proteins by induction of abnormal cell shape in fission yeast. Proceedings of the National Academy of Sciences of the United States of America. 91: 4589-93. PMID 8183953 DOI: 10.1073/Pnas.91.10.4589  1
1994 Edgar BA, Lehman DA, O'Farrell PH. Transcriptional regulation of string (cdc25): a link between developmental programming and the cell cycle. Development (Cambridge, England). 120: 3131-43. PMID 7720557  1
1994 Schubiger G, Edgar B. Using inhibitors to study embryogenesis. Methods in Cell Biology. 44: 697-713. PMID 7707976 DOI: 10.1016/S0091-679X(08)60939-5  1
1994 Edgar BA, Sprenger F, Duronio RJ, Leopold P, O'Farrell PH. Distinct molecular mechanism regulate cell cycle timing at successive stages of Drosophila embryogenesis. Genes & Development. 8: 440-52. PMID 7510257 DOI: 10.1101/Gad.8.4.440  1
1990 Edgar BA, O'Farrell PH. The three postblastoderm cell cycles of Drosophila embryogenesis are regulated in G2 by string. Cell. 62: 469-80. PMID 2199063 DOI: 10.1016/0092-8674(90)90012-4  1
1989 Edgar BA, O'Farrell PH. Genetic control of cell division patterns in the Drosophila embryo. Cell. 57: 177-87. PMID 2702688 DOI: 10.1016/0092-8674(89)90183-9  1
1989 O'Farrell PH, Edgar BA, Lakich D, Lehner CF. Directing cell division during development. Science (New York, N.Y.). 246: 635-40. PMID 2683080 DOI: 10.1126/Science.2683080  1
1989 Edgar BA, Odell GM, Schubiger G. A genetic switch, based on negative regulation, sharpens stripes in Drosophila embryos. Developmental Genetics. 10: 124-42. PMID 2500279 DOI: 10.1002/dvg.1020100303  1
1988 Weir MP, Edgar BA, Kornberg T, Schubiger G. Spatial regulation of engrailed expression in the Drosophila embryo. Genes & Development. 2: 1194-203. PMID 2461329 DOI: 10.1101/Gad.2.9.1194  1
1987 Edgar BA, Odell GM, Schubiger G. Cytoarchitecture and the patterning of fushi tarazu expression in the Drosophila blastoderm. Genes & Development. 1: 1226-37. PMID 3123317 DOI: 10.1101/Gad.1.10.1226  1
1986 Edgar BA, Weir MP, Schubiger G, Kornberg T. Repression and turnover pattern fushi tarazu RNA in the early Drosophila embryo. Cell. 47: 747-54. PMID 3096577 DOI: 10.1016/0092-8674(86)90517-9  1
1986 Edgar BA, Kiehle CP, Schubiger G. Cell cycle control by the nucleo-cytoplasmic ratio in early Drosophila development. Cell. 44: 365-72. PMID 3080248 DOI: 10.1016/0092-8674(86)90771-3  1
1986 Edgar BA, Schubiger G. Parameters controlling transcriptional activation during early Drosophila development. Cell. 44: 871-7. PMID 2420468 DOI: 10.1016/0092-8674(86)90009-7  1
Show low-probability matches.