| Year |
Citation |
Score |
| 2018 |
Skepper CK, Moreau RJ, Appleton BA, Benton BM, Drumm JE, Feng BY, Geng M, Lingel A, Lu Y, Mamo M, Mergo W, Mostafavi M, Rath CM, Steffek M, Takeoka KT, et al. Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity. Journal of Medicinal Chemistry. PMID 29551072 DOI: 10.1021/Acs.Jmedchem.7B01861 |
0.339 |
|
| 2017 |
Rath CM, Benton BM, De Vicente J, Drumm JE, Geng M, Li C, Moreau RJ, Shen X, Skepper CK, Steffek M, Takeoka K, Wang L, Wei JR, Xu W, Zhang Q, et al. Optimization of CoaD inhibitors against Gram-negative organisms through targeted metabolomics. Acs Infectious Diseases. PMID 29243909 DOI: 10.1021/Acsinfecdis.7B00214 |
0.36 |
|
| 2017 |
Hong S, Moritz TJ, Rath CM, Tamrakar P, Lee P, Krucker T, Lee LP. Assessing Antibiotic Permeability of Gram-Negative Bacteria via Nanofluidics. Acs Nano. PMID 28605582 DOI: 10.1021/Acsnano.7B02267 |
0.337 |
|
| 2016 |
Dovala D, Rath CM, Hu Q, Sawyer WS, Shia S, Elling RA, Knapp MS, Metzger LE. Structure-guided enzymology of the lipid A acyltransferase LpxM reveals a dual activity mechanism. Proceedings of the National Academy of Sciences of the United States of America. PMID 27681620 DOI: 10.1073/Pnas.1610746113 |
0.444 |
|
| 2016 |
Richie DL, Takeoka KT, Bojkovic J, Metzger LE, Rath CM, Sawyer WS, Wei JR, Dean CR. Toxic Accumulation of LPS Pathway Intermediates Underlies the Requirement of LpxH for Growth of Acinetobacter baumannii ATCC 19606. Plos One. 11: e0160918. PMID 27526195 DOI: 10.1371/Journal.Pone.0160918 |
0.382 |
|
| 2015 |
Bojkovic J, Richie DL, Six DA, Rath CM, Sawyer WS, Hu Q, Dean CR. Characterization of an Acinetobacter baumannii lptD Deletion Strain; Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis. Journal of Bacteriology. PMID 26668262 DOI: 10.1128/Jb.00639-15 |
0.345 |
|
| 2015 |
Dovala D, Sawyer WS, Rath CM, Metzger LE. Rapid analysis of protein expression and solubility with the SpyTag-SpyCatcher system. Protein Expression and Purification. PMID 26405011 DOI: 10.1016/J.Pep.2015.09.021 |
0.332 |
|
| 2015 |
Rateb ME, Zhai Y, Ehrner E, Rath CM, Wang X, Tabudravu J, Ebel R, Bibb M, Kyeremeh K, Dorrestein PC, Hong K, Jaspars M, Deng H. Legonaridin, a new member of linaridin RiPP from a Ghanaian Streptomyces isolate. Organic & Biomolecular Chemistry. 13: 9585-92. PMID 26256511 DOI: 10.1039/C5Ob01269D |
0.357 |
|
| 2013 |
Yang JY, Sanchez LM, Rath CM, Liu X, Boudreau PD, Bruns N, Glukhov E, Wodtke A, de Felicio R, Fenner A, Wong WR, Linington RG, Zhang L, Debonsi HM, Gerwick WH, et al. Molecular networking as a dereplication strategy. Journal of Natural Products. 76: 1686-99. PMID 24025162 DOI: 10.1021/Np400413S |
0.304 |
|
| 2013 |
Hansen DA, Rath CM, Eisman EB, Narayan AR, Kittendorf JD, Mortison JD, Yoon YJ, Sherman DH. Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin. Journal of the American Chemical Society. 135: 11232-8. PMID 23866020 DOI: 10.1021/Ja404134F |
0.667 |
|
| 2012 |
Rath CM, Alexandrov T, Higginbottom SK, Song J, Milla ME, Fischbach MA, Sonnenburg JL, Dorrestein PC. Molecular analysis of model gut microbiotas by imaging mass spectrometry and nanodesorption electrospray ionization reveals dietary metabolite transformations. Analytical Chemistry. 84: 9259-67. PMID 23009651 DOI: 10.1021/Ac302039U |
0.354 |
|
| 2012 |
Chemler JA, Buchholz TJ, Geders TW, Akey DL, Rath CM, Chlipala GE, Smith JL, Sherman DH. Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor. Journal of the American Chemical Society. 134: 7359-66. PMID 22480290 DOI: 10.1021/Ja2112228 |
0.758 |
|
| 2012 |
Rath CM, Dorrestein PC. The bacterial chemical repertoire mediates metabolic exchange within gut microbiomes. Current Opinion in Microbiology. 15: 147-54. PMID 22209085 DOI: 10.1016/J.Mib.2011.12.009 |
0.342 |
|
| 2011 |
Bonnett SA, Rath CM, Shareef AR, Joels JR, Chemler JA, Håkansson K, Reynolds K, Sherman DH. Acyl-CoA subunit selectivity in the pikromycin polyketide synthase PikAIV: steady-state kinetics and active-site occupancy analysis by FTICR-MS. Chemistry & Biology. 18: 1075-81. PMID 21944746 DOI: 10.1016/J.Chembiol.2011.07.016 |
0.702 |
|
| 2011 |
Rath CM, Janto B, Earl J, Ahmed A, Hu FZ, Hiller L, Dahlgren M, Kreft R, Yu F, Wolff JJ, Kweon HK, Christiansen MA, Håkansson K, Williams RM, Ehrlich GD, et al. Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743. Acs Chemical Biology. 6: 1244-56. PMID 21875091 DOI: 10.1021/Cb200244T |
0.741 |
|
| 2011 |
Ding Y, Rath CM, Bolduc KL, Håkansson K, Sherman DH. Chemoenzymatic synthesis of cryptophycin anticancer agents by an ester bond-forming non-ribosomal peptide synthetase module. Journal of the American Chemical Society. 133: 14492-5. PMID 21823639 DOI: 10.1021/Ja204716F |
0.746 |
|
| 2010 |
Buchholz TJ, Rath CM, Lopanik NB, Gardner NP, Håkansson K, Sherman DH. Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase. Chemistry & Biology. 17: 1092-100. PMID 21035732 DOI: 10.1016/J.Chembiol.2010.08.008 |
0.743 |
|
| 2010 |
Scaglione JB, Akey DL, Sullivan R, Kittendorf JD, Rath CM, Kim ES, Smith JL, Sherman DH. Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase. Angewandte Chemie (International Ed. in English). 49: 5726-30. PMID 20623733 DOI: 10.1002/Anie.201000032 |
0.551 |
|
| 2010 |
Rath CM, Scaglione JB, Kittendorf JD, Sherman DH. NRPS/PKS hybrid enzymes and their natural products Comprehensive Natural Products Ii: Chemistry and Biology. 1: 453-492. |
0.515 |
|
| 2008 |
Lopanik NB, Shields JA, Buchholz TJ, Rath CM, Hothersall J, Haygood MG, Håkansson K, Thomas CM, Sherman DH. In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont. Chemistry & Biology. 15: 1175-86. PMID 19022178 DOI: 10.1016/J.Chembiol.2008.09.013 |
0.739 |
|
| 2008 |
Pfleger BF, Kim Y, Nusca TD, Maltseva N, Lee JY, Rath CM, Scaglione JB, Janes BK, Anderson EC, Bergman NH, Hanna PC, Joachimiak A, Sherman DH. Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 17133-8. PMID 18955706 DOI: 10.1073/Pnas.0808118105 |
0.72 |
|
| 2003 |
Amagata T, Rath C, Rigot JF, Tarlov N, Tenney K, Valeriote FA, Crews P. Structures and cytotoxic properties of trichoverroids and their macrolide analogues produced by saltwater culture of Myrothecium verrucaria Journal of Medicinal Chemistry. 46: 4342-4350. PMID 13678412 DOI: 10.1021/Jm030090T |
0.309 |
|
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