Ethan Bier - Publications

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93 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Guichard A, Haque T, Bobik M, Xu XS, Klanseck C, Kushwah RBS, Berni M, Kaduskar B, Gantz VM, Bier E. Efficient allelic-drive in Drosophila. Nature Communications. 10: 1640. PMID 30967548 DOI: 10.1038/s41467-019-09694-w  0.64
2018 Negreiros E, Herszterg S, Hwa K, Câmara A, Dias WB, Carneiro K, Bier E, Todeschini A, Araujo H. N-linked glycosylation restricts the function of short gastrulation to bind and shuttle BMPs. Development (Cambridge, England). PMID 30355725 DOI: 10.1242/dev.167338  0.84
2018 Liu JZ, Ali SR, Bier E, Nizet V. Innate Immune Interactions between Bacillus anthracis and Host Neutrophils. Frontiers in Cellular and Infection Microbiology. 8: 2. PMID 29404280 DOI: 10.3389/fcimb.2018.00002  0.48
2017 Guichard A, Jain P, Moayeri M, Schwartz R, Chin S, Zhu L, Cruz-Moreno B, Liu JZ, Aguilar B, Hollands A, Leppla SH, Nizet V, Bier E. Anthrax edema toxin disrupts distinct steps in Rab11-dependent junctional transport. Plos Pathogens. 13: e1006603. PMID 28945820 DOI: 10.1371/journal.ppat.1006603  0.64
2017 Smelkinson MG, Guichard A, Teijaro JR, Malur M, Loureiro ME, Jain P, Ganesan S, Zúñiga EI, Krug RM, Oldstone MB, Bier E. Influenza NS1 directly modulates Hedgehog signaling during infection. Plos Pathogens. 13: e1006588. PMID 28837667 DOI: 10.1371/journal.ppat.1006588  0.64
2015 Gantz VM, Bier E. The dawn of active genetics. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 26660392 DOI: 10.1002/bies.201500102  1
2015 Gantz VM, Jasinskiene N, Tatarenkova O, Fazekas A, Macias VM, Bier E, James AA. Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi. Proceedings of the National Academy of Sciences of the United States of America. PMID 26598698 DOI: 10.1073/pnas.1521077112  1
2015 Bier E, De Robertis EM. BMP gradients: A paradigm for morphogen-mediated developmental patterning Science. 348. PMID 26113727 DOI: 10.1126/science.aaa5838  1
2015 Gantz VM, Bier E. Genome editing. The mutagenic chain reaction: a method for converting heterozygous to homozygous mutations. Science (New York, N.Y.). 348: 442-4. PMID 25908821 DOI: 10.1126/science.aaa5945  1
2015 Bier E, Nizet V. Hedgehog: linking uracil to innate defense. Cell Host & Microbe. 17: 146-8. PMID 25674980 DOI: 10.1016/j.chom.2015.01.010  1
2014 Esteves FF, Springhorn A, Kague E, Taylor E, Pyrowolakis G, Fisher S, Bier E. BMPs regulate msx gene expression in the dorsal neuroectoderm of Drosophila and vertebrates by distinct mechanisms. Plos Genetics. 10: e1004625. PMID 25210771 DOI: 10.1371/journal.pgen.1004625  1
2014 Guichard A, Nizet V, Bier E. RAB11-mediated trafficking in host-pathogen interactions. Nature Reviews. Microbiology. 12: 624-34. PMID 25118884 DOI: 10.1038/nrmicro3325  1
2013 Guichard A, Cruz-Moreno B, Cruz-Moreno BC, Aguilar B, van Sorge NM, Kuang J, Kurkciyan AA, Wang Z, Hang S, Pineton de Chambrun GP, McCole DF, Watnick P, Nizet V, Bier E. Cholera toxin disrupts barrier function by inhibiting exocyst-mediated trafficking of host proteins to intestinal cell junctions. Cell Host & Microbe. 14: 294-305. PMID 24034615 DOI: 10.1016/j.chom.2013.08.001  1
2012 Lee JH, Budanov AV, Talukdar S, Park EJ, Park HL, Park HW, Bandyopadhyay G, Li N, Aghajan M, Jang I, Wolfe AM, Perkins GA, Ellisman MH, Bier E, Scadeng M, et al. Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3. Cell Metabolism. 16: 311-21. PMID 22958918 DOI: 10.1016/j.cmet.2012.08.004  1
2012 Bier E, Guichard A. Deconstructing host-pathogen interactions in Drosophila. Disease Models & Mechanisms. 5: 48-61. PMID 21979942 DOI: 10.1242/dmm.000406  1
2012 Guichard A, Nizet V, Bier E. New insights into the biological effects of anthrax toxins: linking cellular to organismal responses. Microbes and Infection / Institut Pasteur. 14: 97-118. PMID 21930233 DOI: 10.1016/j.micinf.2011.08.016  1
2011 Grossman TR, Gamliel A, Wessells RJ, Taghli-Lamallem O, Jepsen K, Ocorr K, Korenberg JR, Peterson KL, Rosenfeld MG, Bodmer R, Bier E. Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects. Plos Genetics. 7: e1002344. PMID 22072978 DOI: 10.1371/journal.pgen.1002344  1
2011 McHale P, Mizutani CM, Kosman D, MacKay DL, Belu M, Hermann A, McGinnis W, Bier E, Hwa T. Gene length may contribute to graded transcriptional responses in the Drosophila embryo. Developmental Biology. 360: 230-40. PMID 21920356 DOI: 10.1016/j.ydbio.2011.08.016  1
2011 Wangler MF, Reiter LT, Zimm G, Trimble-Morgan J, Wu J, Bier E. Antioxidant proteins TSA and PAG interact synergistically with Presenilin to modulate Notch signaling in Drosophila. Protein & Cell. 2: 554-63. PMID 21822800 DOI: 10.1007/s13238-011-1073-7  1
2011 Bier E. Evolution of development: diversified dorsoventral patterning. Current Biology : Cb. 21: R591-4. PMID 21820625 DOI: 10.1016/j.cub.2011.06.037  1
2011 Do LH, Bier E. The Booly aliasing resource: a database of grouped biological identifiers. Bioinformation. 6: 83-5. PMID 21544171  1
2011 Lee JH, Bier E. The Protective Role of Sestrins Against Chronic TOR Activation and Oxidative Stress Oxidative Stress in Vertebrates and Invertebrates: Molecular Aspects of Cell Signaling. 337-346. DOI: 10.1002/9781118148143.ch24  1
2010 Guichard A, McGillivray SM, Cruz-Moreno B, van Sorge NM, Nizet V, Bier E. Anthrax toxins cooperatively inhibit endocytic recycling by the Rab11/Sec15 exocyst. Nature. 467: 854-8. PMID 20944747 DOI: 10.1038/nature09446  1
2010 Do LH, Esteves FF, Karten HJ, Bier E. Booly: a new data integration platform. Bmc Bioinformatics. 11: 513. PMID 20942966 DOI: 10.1186/1471-2105-11-513  1
2010 Lee JH, Bodmer R, Bier E, Karin M. Sestrins at the crossroad between stress and aging. Aging. 2: 369-74. PMID 20606249 DOI: v2/n6/full/100157.html  1
2010 Kang KH, Bier E. dHIP14-dependent palmitoylation promotes secretion of the BMP antagonist Sog. Developmental Biology. 346: 1-10. PMID 20599894 DOI: 10.1016/j.ydbio.2010.06.024  1
2010 Lee JH, Budanov AV, Park EJ, Birse R, Kim TE, Perkins GA, Ocorr K, Ellisman MH, Bodmer R, Bier E, Karin M. Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies. Science (New York, N.Y.). 327: 1223-8. PMID 20203043 DOI: 10.1126/science.1182228  1
2010 Mizutani CM, Bier E. Bone Morphogenetic Protein (BMP) Signaling in the Neuroectoderm Encyclopedia of Neuroscience. 273-282. DOI: 10.1016/B978-008045046-9.01047-0  1
2008 Bier E. Intriguing extracellular regulation of BMP signaling. Developmental Cell. 15: 176-7. PMID 18694555 DOI: 10.1016/j.devcel.2008.07.012  1
2008 Mizutani CM, Bier E. EvoD/Vo: the origins of BMP signalling in the neuroectoderm. Nature Reviews. Genetics. 9: 663-77. PMID 18679435 DOI: 10.1038/nrg2417  1
2008 Iyadurai SJ, Robinson JT, Ma L, He Y, Mische S, Li MG, Brown W, Guichard A, Bier E, Hays TS. Dynein and Star interact in EGFR signaling and ligand trafficking. Journal of Cell Science. 121: 2643-51. PMID 18653542 DOI: 10.1242/jcs.027144  1
2007 Reiter LT, Do LH, Fischer MS, Hong NA, Bier E. Accentuate the negative: proteome comparisons using the negative proteome database. Fly. 1: 164-71. PMID 18820470  1
2007 Beaver W, Kosman D, Tedeschi G, Bier E, McGinnis W, Freund Y. Segmentation of nuclei in confocal image stacks using performance based thresholding 2007 4th Ieee International Symposium On Biomedical Imaging: From Nano to Macro - Proceedings. 53-56. DOI: 10.1109/ISBI.2007.356786  1
2006 Mizutani CM, Meyer N, Roelink H, Bier E. Threshold-dependent BMP-mediated repression: a model for a conserved mechanism that patterns the neuroectoderm. Plos Biology. 4: e313. PMID 16968133 DOI: 10.1371/journal.pbio.0040313  1
2006 Bier E. Antioxidants put Parkinson flies back in the PINK. Proceedings of the National Academy of Sciences of the United States of America. 103: 13269-70. PMID 16938856 DOI: 10.1073/pnas.0606288103  1
2006 Reiter LT, Seagroves TN, Bowers M, Bier E. Expression of the Rho-GEF Pbl/ECT2 is regulated by the UBE3A E3 ubiquitin ligase. Human Molecular Genetics. 15: 2825-35. PMID 16905559 DOI: 10.1093/hmg/ddl225  1
2006 Carneiro K, Fontenele M, Negreiros E, Lopes E, Bier E, Araujo H. Graded maternal short gastrulation protein contributes to embryonic dorsal-ventral patterning by delayed induction. Developmental Biology. 296: 203-18. PMID 16781701 DOI: 10.1016/j.ydbio.2006.04.453  1
2006 Guichard A, Park JM, Cruz-Moreno B, Karin M, Bier E. Anthrax lethal factor and edema factor act on conserved targets in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 103: 3244-9. PMID 16455799 DOI: 10.1073/pnas.0510748103  1
2005 Nakagawa T, Guichard A, Castro CP, Xiao Y, Rizen M, Zhang HZ, Hu D, Bang A, Helms J, Bier E, Derynck R. Characterization of a human rhomboid homolog, p100hRho/RHBDF1, which interacts with TGF-alpha family ligands. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 233: 1315-31. PMID 15965977 DOI: 10.1002/dvdy.20450  1
2005 Mizutani CM, Nie Q, Wan FY, Zhang YT, Vilmos P, Sousa-Neves R, Bier E, Marsh JL, Lander AD. Formation of the BMP activity gradient in the Drosophila embryo. Developmental Cell. 8: 915-24. PMID 15935780 DOI: 10.1016/j.devcel.2005.04.009  1
2005 Bier E. Drosophila, the golden bug, emerges as a tool for human genetics. Nature Reviews. Genetics. 6: 9-23. PMID 15630418 DOI: 10.1038/nrg1503  1
2004 Bier E, Bodmer R. Drosophila, an emerging model for cardiac disease. Gene. 342: 1-11. PMID 15527959 DOI: 10.1016/j.gene.2004.07.018  1
2004 Kosman D, Mizutani CM, Lemons D, Cox WG, McGinnis W, Bier E. Multiplex detection of RNA expression in Drosophila embryos. Science (New York, N.Y.). 305: 846. PMID 15297669 DOI: 10.1126/science.1099247  1
2004 Yu K, Kang KH, Heine P, Pyati U, Srinivasan S, Biehs B, Kimelman D, Bier E. Cysteine repeat domains and adjacent sequences determine distinct bone morphogenetic protein modulatory activities of the Drosophila Sog protein. Genetics. 166: 1323-36. PMID 15082551 DOI: 10.1534/genetics.166.3.1323  1
2004 Cook O, Biehs B, Bier E. brinker and optomotor-blind act coordinately to initiate development of the L5 wing vein primordium in Drosophila. Development (Cambridge, England). 131: 2113-24. PMID 15073155 DOI: 10.1242/dev.01100  1
2003 Araujo H, Negreiros E, Bier E. Integrins modulate Sog activity in the Drosophila wing. Development (Cambridge, England). 130: 3851-64. PMID 12835400 DOI: 10.1242/dev.00613  1
2003 Hériché JK, Ang D, Bier E, O'Farrell PH. Involvement of an SCFSlmb complex in timely elimination of E2F upon initiation of DNA replication in Drosophila. Bmc Genetics. 4: 9. PMID 12787468 DOI: 10.1186/1471-2156-4-9  1
2003 Lunde K, Trimble JL, Guichard A, Guss KA, Nauber U, Bier E. Activation of the knirps locus links patterning to morphogenesis of the second wing vein in Drosophila. Development (Cambridge, England). 130: 235-48. PMID 12466192 DOI: 10.1242/dev.00207  1
2002 Reiter LT, Bier E. Using Drosophila melanogaster to uncover human disease gene function and potential drug target proteins. Expert Opinion On Therapeutic Targets. 6: 387-99. PMID 12223075 DOI: 10.1517/14728222.6.3.387  1
2002 Guichard A, Srinivasan S, Zimm G, Bier E. A screen for dominant mutations applied to components in the Drosophila EGF-R pathway. Proceedings of the National Academy of Sciences of the United States of America. 99: 3752-7. PMID 11904431 DOI: 10.1073/pnas.052028699  1
2002 Srinivasan S, Rashka KE, Bier E. Creation of a Sog morphogen gradient in the Drosophila embryo. Developmental Cell. 2: 91-101. PMID 11782317 DOI: 10.1016/S1534-5807(01)00097-1  1
2002 Chien S, Reiter LT, Bier E, Gribskov M. Homophila: human disease gene cognates in Drosophila. Nucleic Acids Research. 30: 149-51. PMID 11752278  1
2001 Reiter LT, Potocki L, Chien S, Gribskov M, Bier E. A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster. Genome Research. 11: 1114-25. PMID 11381037 DOI: 10.1101/gr.169101  1
2000 Guichard A, Roark M, Ronshaugen M, Bier E. brother of rhomboid, a rhomboid-related gene expressed during early Drosophila oogenesis, promotes EGF-R/MAPK signaling. Developmental Biology. 226: 255-66. PMID 11023685 DOI: 10.1006/dbio.2000.9851  1
2000 Araujo H, Bier E. sog and dpp exert opposing maternal functions to modify toll signaling and pattern the dorsoventral axis of the Drosophila embryo. Development (Cambridge, England). 127: 3631-44. PMID 10903186  1
2000 Bier E. Drawing lines in the Drosophila wing: initiation of wing vein development. Current Opinion in Genetics & Development. 10: 393-8. PMID 10889058 DOI: 10.1016/S0959-437X(00)00102-7  1
2000 Yu K, Srinivasan S, Shimmi O, Biehs B, Rashka KE, Kimelman D, O'Connor MB, Bier E. Processing of the Drosophila Sog protein creates a novel BMP inhibitory activity. Development (Cambridge, England). 127: 2143-54. PMID 10769238  1
2000 Mohler J, Seecoomar M, Agarwal S, Bier E, Hsai J. Activation of knot (kn) specifies the 3-4 intervein region in the Drosophila wing. Development (Cambridge, England). 127: 55-63. PMID 10654600  1
1999 Guichard A, Biehs B, Sturtevant MA, Wickline L, Chacko J, Howard K, Bier E. rhomboid and Star interact synergistically to promote EGFR/MAPK signaling during Drosophila wing vein development. Development (Cambridge, England). 126: 2663-76. PMID 10331978  1
1999 Bier E. Developmental biology. A unity of opposites. Nature. 398: 375-6. PMID 10201364 DOI: 10.1038/18778  1
1998 Biehs B, Sturtevant MA, Bier E. Boundaries in the Drosophila wing imaginal disc organize vein-specific genetic programs. Development (Cambridge, England). 125: 4245-57. PMID 9753679  1
1998 Lunde K, Biehs B, Nauber U, Bier E. The knirps and knirps-related genes organize development of the second wing vein in Drosophila. Development (Cambridge, England). 125: 4145-54. PMID 9753669  1
1998 Bier E. Localized activation of RTK/MAPK pathways during Drosophila development. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 20: 189-94. PMID 9631645 DOI: 10.1002/(SICI)1521-1878(199803)20:3<189::AID-BIES1>3.0.CO;2-N  1
1997 Bier E. Anti-neural-inhibition: a conserved mechanism for neural induction. Cell. 89: 681-4. PMID 9182755  1
1997 Sturtevant MA, Biehs B, Marin E, Bier E. The spalt gene links the A/P compartment boundary to a linear adult structure in the Drosophila wing. Development (Cambridge, England). 124: 21-32. PMID 9006064  1
1996 Yu K, Sturtevant MA, Biehs B, François V, Padgett RW, Blackman RK, Bier E. The Drosophila decapentaplegic and short gastrulation genes function antagonistically during adult wing vein development. Development (Cambridge, England). 122: 4033-44. PMID 9012523  1
1996 Biehs B, François V, Bier E. The Drosophila short gastrulation gene prevents Dpp from autoactivating and suppressing neurogenesis in the neuroectoderm. Genes & Development. 10: 2922-34. PMID 8918893  1
1996 Sturtevant MA, Roark M, O'Neill JW, Biehs B, Colley N, Bier E. The Drosophila rhomboid protein is concentrated in patches at the apical cell surface. Developmental Biology. 174: 298-309. PMID 8631502 DOI: 10.1006/dbio.1996.0075  1
1995 Emery JF, Bier E. Specificity of CNS and PNS regulatory subelements comprising pan-neural enhancers of the deadpan and scratch genes is achieved by repression. Development (Cambridge, England). 121: 3549-60. PMID 8582269  1
1995 Schmidt J, Francois V, Bier E, Kimelman D. Drosophila short gastrulation induces an ectopic axis in Xenopus: evidence for conserved mechanisms of dorsal-ventral patterning. Development (Cambridge, England). 121: 4319-28. PMID 8575332  1
1995 François V, Bier E. Xenopus chordin and Drosophila short gastrulation genes encode homologous proteins functioning in dorsal-ventral axis formation. Cell. 80: 19-20. PMID 7813014 DOI: 10.1016/0092-8674(95)90446-8  1
1995 Guo M, Bier E, Jan LY, Jan YN. tramtrack acts downstream of numb to specify distinct daughter cell fates during asymmetric cell divisions in the Drosophila PNS. Neuron. 14: 913-25. PMID 7748559 DOI: 10.1016/0896-6273(95)90330-5  1
1995 Sturtevant MA, Bier E. Analysis of the genetic hierarchy guiding wing vein development in Drosophila. Development (Cambridge, England). 121: 785-801. PMID 7720583  1
1995 Roark M, Sturtevant MA, Emery J, Vaessin H, Grell E, Bier E. scratch, a pan-neural gene encoding a zinc finger protein related to snail, promotes neuronal development. Genes & Development. 9: 2384-98. PMID 7557390  1
1994 Ip YT, Levine M, Bier E. Neurogenic expression of snail is controlled by separable CNS and PNS promoter elements. Development (Cambridge, England). 120: 199-207. PMID 8119127  1
1994 Francois V, Solloway M, O'Neill JW, Emery J, Bier E. Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene. Genes & Development. 8: 2602-16. PMID 7958919  1
1994 Fristrom D, Gotwals P, Eaton S, Kornberg TB, Sturtevant M, Bier E, Fristrom JW. Blistered: a gene required for vein/intervein formation in wings of Drosophila. Development (Cambridge, England). 120: 2661-71. PMID 7956840  1
1994 Sturtevant MA, O'Neill JW, Bier E. Down-regulation of Drosophila Egf-r mRNA levels following hyperactivated receptor signaling. Development (Cambridge, England). 120: 2593-600. PMID 7956834  1
1994 Noll R, Sturtevant MA, Gollapudi RR, Bier E. New functions of the Drosophila rhomboid gene during embryonic and adult development are revealed by a novel genetic method, enhancer piracy. Development (Cambridge, England). 120: 2329-38. PMID 7925033  1
1994 O'Neill JW, Bier E. Double-label in situ hybridization using biotin and digoxigenin-tagged RNA probes. Biotechniques. 17: 870, 874-5. PMID 7840966  1
1993 Sturtevant MA, Roark M, Bier E. The Drosophila rhomboid gene mediates the localized formation of wing veins and interacts genetically with components of the EGF-R signaling pathway. Genes & Development. 7: 961-73. PMID 8504935  1
1992 Rutledge BJ, Zhang K, Bier E, Jan YN, Perrimon N. The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis. Genes & Development. 6: 1503-17. PMID 1644292  1
1992 Bellen HJ, Vaessin H, Bier E, Kolodkin A, D'Evelyn D, Kooyer S, Jan YN. The Drosophila couch potato gene: an essential gene required for normal adult behavior. Genetics. 131: 365-75. PMID 1644278  1
1992 Younger-Shepherd S, Vaessin H, Bier E, Jan LY, Jan YN. deadpan, an essential pan-neural gene encoding an HLH protein, acts as a denominator in Drosophila sex determination. Cell. 70: 911-22. PMID 1525829 DOI: 10.1016/0092-8674(92)90242-5  1
1992 Bier E, Vaessin H, Younger-Shepherd S, Jan LY, Jan YN. deadpan, an essential pan-neural gene in Drosophila, encodes a helix-loop-helix protein similar to the hairy gene product. Genes & Development. 6: 2137-51. PMID 1427077  1
1992 Ip YT, Park RE, Kosman D, Bier E, Levine M. The dorsal gradient morphogen regulates stripes of rhomboid expression in the presumptive neuroectoderm of the Drosophila embryo. Genes & Development. 6: 1728-39. PMID 1325394  1
1991 Vaessin H, Grell E, Wolff E, Bier E, Jan LY, Jan YN. prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila. Cell. 67: 941-53. PMID 1720353 DOI: 10.1016/0092-8674(91)90367-8  1
1990 Vaessin H, Caudy M, Bier E, Jan LY, Jan YN. Role of helix-loop-helix proteins in Drosophila neurogenesis. Cold Spring Harbor Symposia On Quantitative Biology. 55: 239-45. PMID 2132818  1
1990 Bier E, Jan LY, Jan YN. rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster. Genes & Development. 4: 190-203. PMID 2110920  1
1989 Bier E, Vaessin H, Shepherd S, Lee K, McCall K, Barbel S, Ackerman L, Carretto R, Uemura T, Grell E. Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector. Genes & Development. 3: 1273-87. PMID 2558049  1
1988 Bier E, Ackerman L, Barbel S, Jan L, Jan YN. Identification and characterization of a neuron-specific nuclear antigen in Drosophila. Science (New York, N.Y.). 240: 913-6. PMID 3129785  1
1988 Georgopoulos K, van den Elsen P, Bier E, Maxam A, Terhorst C. A T cell-specific enhancer is located in a DNase I-hypersensitive area at the 3' end of the CD3-delta gene. The Embo Journal. 7: 2401-7. PMID 2847918  1
1985 Bier E, Hashimoto Y, Greene MI, Maxam AM. Active T-cell receptor genes have intron deoxyribonuclease hypersensitive sites. Science (New York, N.Y.). 229: 528-34. PMID 3927483  1
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