Jim Posakony - Publications

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75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Miller SW, Rebeiz M, Atanasov JE, Posakony JW. Neural precursor-specific expression of multiple Drosophila genes is driven by dual enhancer modules with overlapping function. Proceedings of the National Academy of Sciences of the United States of America. 111: 17194-9. PMID 25404315 DOI: 10.1073/pnas.1415308111  1
2014 Liu F, Posakony JW. An enhancer composed of interlocking submodules controls transcriptional autoregulation of suppressor of hairless. Developmental Cell. 29: 88-101. PMID 24735880 DOI: 10.1016/j.devcel.2014.02.005  1
2012 Liu F, Posakony JW. Role of architecture in the function and specificity of two Notch-regulated transcriptional enhancer modules. Plos Genetics. 8: e1002796. PMID 22792075 DOI: 10.1371/journal.pgen.1002796  1
2012 Rebeiz M, Castro B, Liu F, Yue F, Posakony JW. Ancestral and conserved cis-regulatory architectures in developmental control genes. Developmental Biology. 362: 282-94. PMID 22185795 DOI: 10.1016/j.ydbio.2011.12.011  1
2012 Hirono K, Margolis JS, Posakony JW, Doe CQ. Identification of hunchback cis-regulatory DNA conferring temporal expression in neuroblasts and neurons. Gene Expression Patterns : Gep. 12: 11-7. PMID 22033538 DOI: 10.1016/j.gep.2011.10.001  1
2011 Nègre N, Brown CD, Ma L, Bristow CA, Miller SW, Wagner U, Kheradpour P, Eaton ML, Loriaux P, Sealfon R, Li Z, Ishii H, Spokony RF, Chen J, Hwang L, ... ... Posakony JW, et al. A cis-regulatory map of the Drosophila genome. Nature. 471: 527-31. PMID 21430782 DOI: 10.1038/nature09990  1
2011 Zhou D, Udpa N, Gersten M, Visk DW, Bashir A, Xue J, Frazer KA, Posakony JW, Subramaniam S, Bafna V, Haddad GG. Experimental selection of hypoxia-tolerant Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 108: 2349-54. PMID 21262834 DOI: 10.1073/pnas.1010643108  1
2011 Rebeiz M, Miller SW, Posakony JW. Notch regulates numb: integration of conditional and autonomous cell fate specification. Development (Cambridge, England). 138: 215-25. PMID 21148185 DOI: 10.1242/dev.050161  1
2010 Roy S, Ernst J, Kharchenko PV, Kheradpour P, Negre N, Eaton ML, Landolin JM, Bristow CA, Ma L, Lin MF, Washietl S, Arshinoff BI, Ay F, Meyer PE, ... ... Posakony JW, et al. Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (New York, N.Y.). 330: 1787-97. PMID 21177974 DOI: 10.1126/science.1198374  1
2009 Fontana JR, Posakony JW. Both inhibition and activation of Notch signaling rely on a conserved Neuralized-binding motif in Bearded proteins and the Notch ligand Delta. Developmental Biology. 333: 373-85. PMID 19580805 DOI: 10.1016/j.ydbio.2009.06.039  1
2009 Miller SW, Avidor-Reiss T, Polyanovsky A, Posakony JW. Complex interplay of three transcription factors in controlling the tormogen differentiation program of Drosophila mechanoreceptors. Developmental Biology. 329: 386-99. PMID 19232522 DOI: 10.1016/j.ydbio.2009.02.009  1
2007 Tsai YC, Yao JG, Chen PH, Posakony JW, Barolo S, Kim J, Sun YH. Upd/Jak/STAT signaling represses wg transcription to allow initiation of morphogenetic furrow in Drosophila eye development. Developmental Biology. 306: 760-71. PMID 17498684 DOI: 10.1016/j.ydbio.2007.04.011  1
2007 Ocorr K, Reeves NL, Wessells RJ, Fink M, Chen HS, Akasaka T, Yasuda S, Metzger JM, Giles W, Posakony JW, Bodmer R. KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging. Proceedings of the National Academy of Sciences of the United States of America. 104: 3943-8. PMID 17360457 DOI: 10.1073/pnas.0609278104  1
2005 Castro B, Barolo S, Bailey AM, Posakony JW. Lateral inhibition in proneural clusters: cis-regulatory logic and default repression by Suppressor of Hairless. Development (Cambridge, England). 132: 3333-44. PMID 15975935 DOI: 10.1242/dev.01920  1
2005 Rebeiz M, Stone T, Posakony JW. An ancient transcriptional regulatory linkage. Developmental Biology. 281: 299-308. PMID 15893980 DOI: 10.1016/j.ydbio.2005.03.004  1
2005 Reeves N, Posakony JW. Genetic programs activated by proneural proteins in the developing Drosophila PNS. Developmental Cell. 8: 413-25. PMID 15737936 DOI: 10.1016/j.devcel.2005.01.020  1
2004 Rebeiz M, Posakony JW. GenePalette: a universal software tool for genome sequence visualization and analysis. Developmental Biology. 271: 431-8. PMID 15223345 DOI: 10.1016/j.ydbio.2004.04.011  1
2004 Barolo S, Castro B, Posakony JW. New Drosophila transgenic reporters: insulated P-element vectors expressing fast-maturing RFP. Biotechniques. 36: 436-40, 442. PMID 15038159  1
2002 Barolo S, Stone T, Bang AG, Posakony JW. Default repression and Notch signaling: Hairless acts as an adaptor to recruit the corepressors Groucho and dCtBP to Suppressor of Hairless. Genes & Development. 16: 1964-76. PMID 12154126 DOI: 10.1101/gad.987402  1
2002 Rebeiz M, Reeves NL, Posakony JW. SCORE: a computational approach to the identification of cis-regulatory modules and target genes in whole-genome sequence data. Site clustering over random expectation. Proceedings of the National Academy of Sciences of the United States of America. 99: 9888-93. PMID 12107285 DOI: 10.1073/pnas.152320899  1
2002 Barolo S, Posakony JW. Three habits of highly effective signaling pathways: principles of transcriptional control by developmental cell signaling. Genes & Development. 16: 1167-81. PMID 12023297 DOI: 10.1101/gad.976502  1
2000 Barolo S, Walker RG, Polyanovsky AD, Freschi G, Keil T, Posakony JW. A notch-independent activity of suppressor of hairless is required for normal mechanoreceptor physiology. Cell. 103: 957-69. PMID 11136980  1
2000 Barolo S, Carver LA, Posakony JW. GFP and beta-galactosidase transformation vectors for promoter/enhancer analysis in Drosophila. Biotechniques. 29: 726, 728, 730, 732. PMID 11056799  1
2000 Lai EC, Bodner R, Posakony JW. The enhancer of split complex of Drosophila includes four Notch-regulated members of the bearded gene family. Development (Cambridge, England). 127: 3441-55. PMID 10903170  1
2000 Lai EC, Bodner R, Kavaler J, Freschi G, Posakony JW. Antagonism of notch signaling activity by members of a novel protein family encoded by the bearded and enhancer of split gene complexes. Development (Cambridge, England). 127: 291-306. PMID 10603347  1
1999 Nellesen DT, Lai EC, Posakony JW. Discrete enhancer elements mediate selective responsiveness of enhancer of split complex genes to common transcriptional activators. Developmental Biology. 213: 33-53. PMID 10452845 DOI: 10.1006/dbio.1999.9324  1
1999 Kavaler J, Fu W, Duan H, Noll M, Posakony JW. An essential role for the Drosophila Pax2 homolog in the differentiation of adult sensory organs. Development (Cambridge, England). 126: 2261-72. PMID 10207150  1
1999 Posakony JW. Birds on a wire and tiling the inner ear. Nature Genetics. 21: 253-4. PMID 10080171 DOI: 10.1038/6760  1
1998 Lai EC, Burks C, Posakony JW. The K box, a conserved 3' UTR sequence motif, negatively regulates accumulation of enhancer of split complex transcripts. Development (Cambridge, England). 125: 4077-88. PMID 9735368  1
1998 Lai EC, Posakony JW. Regulation of Drosophila neurogenesis by RNA:RNA duplexes? Cell. 93: 1103-4. PMID 9657143 DOI: 10.1016/S0092-8674(00)81454-3  1
1997 Lai EC, Posakony JW. The Bearded box, a novel 3' UTR sequence motif, mediates negative post-transcriptional regulation of Bearded and Enhancer of split Complex gene expression. Development (Cambridge, England). 124: 4847-56. PMID 9428421  1
1997 Leviten MW, Lai EC, Posakony JW. The Drosophila gene Bearded encodes a novel small protein and shares 3' UTR sequence motifs with multiple Enhancer of split complex genes. Development (Cambridge, England). 124: 4039-51. PMID 9374401  1
1996 Gho M, Lecourtois M, Géraud G, Posakony JW, Schweisguth F. Subcellular localization of Suppressor of Hairless in Drosophila sense organ cells during Notch signalling. Development (Cambridge, England). 122: 1673-82. PMID 8674407  1
1996 Leviten MW, Posakony JW. Gain-of-function alleles of Bearded interfere with alternative cell fate decisions in Drosophila adult sensory organ development. Developmental Biology. 176: 264-83. PMID 8660866 DOI: 10.1006/dbio.1996.0133  1
1995 Bang AG, Bailey AM, Posakony JW. Hairless promotes stable commitment to the sensory organ precursor cell fate by negatively regulating the activity of the Notch signaling pathway. Developmental Biology. 172: 479-94. PMID 8612965 DOI: 10.1006/dbio.1995.8033  1
1995 Bailey AM, Posakony JW. Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity. Genes & Development. 9: 2609-22. PMID 7590239  1
1995 Margolis JS, Borowsky ML, Steingrímsson E, Shim CW, Lengyel JA, Posakony JW. Posterior stripe expression of hunchback is driven from two promoters by a common enhancer element. Development (Cambridge, England). 121: 3067-77. PMID 7555732  1
1994 Posakony JW. Nature versus nurture: asymmetric cell divisions in Drosophila bristle development. Cell. 76: 415-8. PMID 8313463 DOI: 10.1016/0092-8674(94)90105-8  1
1994 Margolis JS, Borowsky M, Shim CW, Posakony JW. A small region surrounding the distal promoter of the hunchback gene directs maternal expression. Developmental Biology. 163: 381-8. PMID 8200478 DOI: 10.1006/dbio.1994.1156  1
1994 Schweisguth F, Posakony JW. Antagonistic activities of Suppressor of Hairless and Hairless control alternative cell fates in the Drosophila adult epidermis. Development (Cambridge, England). 120: 1433-41. PMID 8050354  1
1994 Van Doren M, Bailey AM, Esnayra J, Ede K, Posakony JW. Negative regulation of proneural gene activity: hairy is a direct transcriptional repressor of achaete. Genes & Development. 8: 2729-42. PMID 7958929  1
1994 Singson A, Leviten MW, Bang AG, Hua XH, Posakony JW. Direct downstream targets of proneural activators in the imaginal disc include genes involved in lateral inhibitory signaling. Genes & Development. 8: 2058-71. PMID 7958878  1
1994 Schweisguth F, Nero P, Posakony JW. The sequence similarity of the Drosophila suppressor of hairless protein to the integrase domain has no functional significance in vivo. Developmental Biology. 166: 812-4. PMID 7813798 DOI: 10.1006/dbio.1994.1359  1
1993 Flegel WA, Singson AW, Margolis JS, Bang AG, Posakony JW, Murre C. Dpbx, a new homeobox gene closely related to the human proto-oncogene pbx1 molecular structure and developmental expression. Mechanisms of Development. 41: 155-61. PMID 8100142 DOI: 10.1016/0925-4773(93)90045-Y  1
1992 Schweisguth F, Posakony JW. Suppressor of Hairless, the Drosophila homolog of the mouse recombination signal-binding protein gene, controls sensory organ cell fates. Cell. 69: 1199-212. PMID 1617730 DOI: 10.1016/0092-8674(92)90641-O  1
1992 Bang AG, Posakony JW. The Drosophila gene Hairless encodes a novel basic protein that controls alternative cell fates in adult sensory organ development. Genes & Development. 6: 1752-69. PMID 1516831  1
1992 Van Doren M, Powell PA, Pasternak D, Singson A, Posakony JW. Spatial regulation of proneural gene activity: auto- and cross-activation of achaete is antagonized by extramacrochaetae. Genes & Development. 6: 2592-605. PMID 1340471  1
1991 Bang AG, Hartenstein V, Posakony JW. Hairless is required for the development of adult sensory organ precursor cells in Drosophila. Development (Cambridge, England). 111: 89-104. PMID 2015800  1
1991 Van Doren M, Ellis HM, Posakony JW. The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete-scute protein complexes. Development (Cambridge, England). 113: 245-55. PMID 1764999  1
1990 Hartenstein V, Posakony JW. A dual function of the Notch gene in Drosophila sensillum development. Developmental Biology. 142: 13-30. PMID 2227090 DOI: 10.1016/0012-1606(90)90147-B  1
1990 Hartenstein V, Posakony JW. Sensillum development in the absence of cell division: the sensillum phenotype of the Drosophila mutant string. Developmental Biology. 138: 147-58. PMID 2106460 DOI: 10.1016/0012-1606(90)90184-K  1
1990 Ellis HM, Spann DR, Posakony JW. extramacrochaetae, a negative regulator of sensory organ development in Drosophila, defines a new class of helix-loop-helix proteins. Cell. 61: 27-38. PMID 1690604 DOI: 10.1016/0092-8674(90)90212-W  1
1989 Hartenstein V, Posakony JW. Development of adult sensilla on the wing and notum of Drosophila melanogaster. Development (Cambridge, England). 107: 389-405. PMID 2517255  1
1988 Oro AE, Ong ES, Margolis JS, Posakony JW, McKeown M, Evans RM. The Drosophila gene knirps-related is a member of the steroid-receptor gene superfamily. Nature. 336: 493-6. PMID 2848202 DOI: 10.1038/336493a0  1
1985 Posakony JW, Fischer JA, Maniatis T. Identification of DNA sequences required for the regulation of Drosophila alcohol dehydrogenase gene expression. Cold Spring Harbor Symposia On Quantitative Biology. 50: 515-20. PMID 3007005  1
1983 Jacobs HT, Posakony JW, Grula JW, Roberts JW, Xin JH, Britten RJ, Davidson EH. Mitochondrial DNA sequences in the nuclear genome of Strongylocentrotus purpuratus. Journal of Molecular Biology. 165: 609-32. PMID 6687903 DOI: 10.1016/S0022-2836(83)80270-8  1
1983 Goldberg DA, Posakony JW, Maniatis T. Correct developmental expression of a cloned alcohol dehydrogenase gene transduced into the Drosophila germ line. Cell. 34: 59-73. PMID 6309412 DOI: 10.1016/0092-8674(83)90136-8  1
1983 Roberts JW, Grula JW, Posakony JW, Hudspeth R, Davidson EH, Britten RJ. Comparison of sea urchin and human mtDNA: evolutionary rearrangement. Proceedings of the National Academy of Sciences of the United States of America. 80: 4614-8. PMID 6308631  1
1983 Posakony JW, Flytzanis CN, Britten RJ, Davidson EH. Interspersed sequence organization and developmental representation of cloned poly(A) RNAs from sea urchin eggs. Journal of Molecular Biology. 167: 361-89. PMID 6191038 DOI: 10.1016/S0022-2836(83)80340-4  1
1983 Cabrera CV, Jacobs HT, Posakony JW, Grula JW, Roberts JW, Britten RJ, Davidson EH. Transcripts of three mitochondrial genes in the RNA of sea urchin eggs and embryos. Developmental Biology. 97: 500-5. PMID 6189753 DOI: 10.1016/0012-1606(83)90107-0  1
1982 Davidson EH, Posakony JW. Repetitive sequence transcripts in development. Nature. 297: 633-5. PMID 6178032 DOI: 10.1038/297633a0  1
1981 Scheller RH, McAllister LB, Crain WR, Durica DS, Posakony JW, Thomas TL, Britten RJ, Davidson EH. Organization and expression of multiple actin genes in the sea urchin. Molecular and Cellular Biology. 1: 609-28. PMID 9279375  1
1981 Posakony JW, Scheller RH, Anderson DM, Britten RJ, Davidson EH. Repetitive sequences of the sea urchin genome. III. Nucleotide sequences of cloned repeat elements. Journal of Molecular Biology. 149: 41-67. PMID 7310878 DOI: 10.1016/0022-2836(81)90332-6  1
1981 Scheller RH, Anderson DM, Posakony JW, McAllister LB, Britten RJ, Davidson EH. Repetitive sequences of the sea urchin genome. II. Subfamily structure and evolutionary conservation. Journal of Molecular Biology. 149: 15-39. PMID 7310877 DOI: 10.1016/0022-2836(81)90258-8  1
1981 Anderson DM, Scheller RH, Posakony JW, McAllister LB, Trabert SG, Beall C, Britten RJ, Davidson EH. Repetitive sequences of the sea urchin genome. Distribution of members of specific repetitive families. Journal of Molecular Biology. 145: 5-28. PMID 7265203  0.88
1981 Thomas TL, Posakony JW, Anderson DM, Britten RJ, Davidson EH. Molecular structure of maternal RNA. Chromosoma. 84: 319-35. PMID 6173173 DOI: 10.1007/BF00286022  1
1980 Efstratiadis A, Posakony JW, Maniatis T, Lawn RM, O'Connell C, Spritz RA, DeRiel JK, Forget BG, Weissman SM, Slightom JL, Blechl AE, Smithies O, Baralle FE, Shoulders CC, Proudfoot NJ. The structure and evolution of the human beta-globin gene family. Cell. 21: 653-68. PMID 6985477 DOI: 10.1016/0092-8674(80)90429-8  1
1980 Moore GP, Costantini FD, Posakony JW, Davidson EH, Britten RJ. Evolutionary conservation of repetitive sequence expression in sea urchin egg RNA's. Science (New York, N.Y.). 208: 1046-8. PMID 6154974  1
1979 Crews S, Ojala D, Posakony J, Nishiguchi J, Attardi G. Nucleotide sequence of a region of human mitochondrial DNA containing the precisely identified origin of replication. Nature. 277: 192-8. PMID 551247 DOI: 10.1038/277192a0  1
1979 Attardi G, Crews ST, Nishiguchi J, Ojala DK, Posakony JW. Nucleotide sequence of a fragment of HeLa-cell mitochondrial DNA containing the precisely localized origin of replication. Cold Spring Harbor Symposia On Quantitative Biology. 43: 179-92. PMID 289450  1
1977 Posakony JW, England JM, Attardi G. Mitochondrial growth and division during the cell cycle in HeLa cells. The Journal of Cell Biology. 74: 468-91. PMID 885911  1
1977 Howell SH, Posakony JW, Hill KR. The cell cycle program of polypeptide labeling in Chlamydomonas reinhardtii. The Journal of Cell Biology. 72: 223-41. PMID 833197  1
1977 Attardi G, Costantino P, England JM, Lynch D, Ojala D, Posakony JW, Storrie B. Mitochondrial and nuclear gene interaction in HeLa cells. Brookhaven Symposia in Biology. 16-35. PMID 754862  1
1977 Wu JR, Pearson WR, Posakony JW, Bonner J. Sequence relationship between long and short repetitive DNA of the rat: a preliminary report. Proceedings of the National Academy of Sciences of the United States of America. 74: 4382-6. PMID 270681  1
1975 Posakony JW, England JM, Attardi G. Morphological heterogeneity of HeLa cell mitochondria visualized by a modified diaminobenzidine staining technique. Journal of Cell Science. 19: 315-29. PMID 53237  1
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