Alan Garen - Publications

Affiliations: 
Molecular Biophysics and Biochemistry Yale University, New Haven, CT 
Area:
Development; Genetics; Medical Sciences; Molecular Biology
Website:
http://medicine.yale.edu/mbb/faculty/alan_garen.profile

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Garen A. From a retrovirus infection of mice to a long noncoding RNA that induces proto-oncogene transcription and oncogenesis via an epigenetic transcription switch. Signal Transduction and Targeted Therapy. 1: 16007. PMID 29263895 DOI: 10.1038/sigtrans.2016.7  0.318
2009 Wang G, Cui Y, Zhang G, Garen A, Song X. Regulation of proto-oncogene transcription, cell proliferation, and tumorigenesis in mice by PSF protein and a VL30 noncoding RNA. Proceedings of the National Academy of Sciences of the United States of America. 106: 16794-8. PMID 19805375 DOI: 10.1073/pnas.0909022106  0.305
2008 Garen A, Song X. Regulatory roles of tumor-suppressor proteins and noncoding RNA in cancer and normal cell functions. International Journal of Cancer. Journal International Du Cancer. 122: 1687-9. PMID 18067128 DOI: 10.1002/ijc.23285  0.33
2005 Song X, Sun Y, Garen A. Roles of PSF protein and VL30 RNA in reversible gene regulation. Proceedings of the National Academy of Sciences of the United States of America. 102: 12189-93. PMID 16079199 DOI: 10.1073/pnas.0505179102  0.348
2004 Song X, Sui A, Garen A. Binding of mouse VL30 retrotransposon RNA to PSF protein induces genes repressed by PSF: effects on steroidogenesis and oncogenesis. Proceedings of the National Academy of Sciences of the United States of America. 101: 621-6. PMID 14704271 DOI: 10.1073/pnas.0307794100  0.328
2002 Song X, Wang B, Bromberg M, Hu Z, Konigsberg W, Garen A. Retroviral-mediated transmission of a mouse VL30 RNA to human melanoma cells promotes metastasis in an immunodeficient mouse model. Proceedings of the National Academy of Sciences of the United States of America. 99: 6269-73. PMID 11959915 DOI: 10.1073/Pnas.092112199  0.335
1999 Bromberg ME, Sundaram R, Homer RJ, Garen A, Konigsberg WH. Role of tissue factor in metastasis: functions of the cytoplasmic and extracellular domains of the molecule. Thrombosis and Haemostasis. 82: 88-92. PMID 10456459 DOI: 10.1055/S-0037-1614634  0.315
1999 Hu Z, Sun Y, Garen A. Targeting tumor vasculature endothelial cells and tumor cells for immunotherapy of human melanoma in a mouse xenograft model. Proceedings of the National Academy of Sciences of the United States of America. 96: 8161-6. PMID 10393965 DOI: 10.1073/pnas.96.14.8161  0.304
1995 Bromberg ME, Konigsberg WH, Madison JF, Pawashe A, Garen A. Tissue factor promotes melanoma metastasis by a pathway independent of blood coagulation. Proceedings of the National Academy of Sciences of the United States of America. 92: 8205-9. PMID 7667269 DOI: 10.1073/Pnas.92.18.8205  0.339
1990 Raha D, Nguyen QD, Garen A. Molecular and developmental analyses of the protein encoded by the Drosophila gene ectodermal. Developmental Genetics. 11: 310-7. PMID 2090376 DOI: 10.1002/Dvg.1020110410  0.342
1987 Swaroop A, Swaroop M, Garen A. Sequence analysis of the complete cDNA and encoded polypeptide for the Glued gene of Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 84: 6501-5. PMID 2819881 DOI: 10.1073/Pnas.84.18.6501  0.354
1986 Paco-Larson ML, Nakanishi Y, Levine M, Garen A. Histochemical analysis of the ecdysterone-regulated expression of the Drosophila genes P1 and LSP-2. Developmental Genetics. 7: 197-203. PMID 3453783 DOI: 10.1002/dvg.1020070405  0.478
1986 Nakanishi Y, Paco-Larson ML, Garen A. DNA homology between the 3'-untranslated regions of a developmentally regulated Drosophila gene and a mouse alpha-interferon gene. Gene. 46: 79-88. PMID 3026929 DOI: 10.1016/0378-1119(86)90169-1  0.337
1986 Swaroop A, Sun JW, Paco-Larson ML, Garen A. Molecular organization and expression of the genetic locus glued in Drosophila melanogaster. Molecular and Cellular Biology. 6: 833-41. PMID 3022132 DOI: 10.1128/Mcb.6.3.833  0.442
1985 Swaroop A, Paco-Larson ML, Garen A. Molecular genetics of a transposon-induced dominant mutation in the Drosophila locus Glued. Proceedings of the National Academy of Sciences of the United States of America. 82: 1751-5. PMID 2984667 DOI: 10.1073/Pnas.82.6.1751  0.357
1983 Nakanishi Y, Garen A. Selective gene expression induced by ecdysterone in cultured fat bodies of Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 80: 2971-5. PMID 6407003 DOI: 10.1073/Pnas.80.10.2971  0.317
1982 Lepesant JA, Levine M, Garen A, Lepesant-Kejzlarvoa J, Rat L, Somme-Martin G. Developmentally regulated gene expression in Drosophila larval fat bodies. Journal of Molecular and Applied Genetics. 1: 371-83. PMID 6818315  0.411
1981 Levine M, Garen A, Lepesant JA, Lepesant-Kejzlarova J. Constancy of somatic DNA organization in developmentally regulated regions of the Drosophila genome. Proceedings of the National Academy of Sciences of the United States of America. 78: 2417-21. PMID 6264475 DOI: 10.1073/Pnas.78.4.2417  0.451
1979 Rice TB, Rice FA, Garen A. Adult abnormalities resulting from a localized blastoderm defect in a maternal-effect mutant of Drosophila. Developmental Biology. 69: 194-201. PMID 109336 DOI: 10.1016/0012-1606(79)90285-9  0.325
1978 Lepesant JA, Kejzlarova-Lepesant J, Garen A. Ecdysone-inducible functions of larval fat bodies in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 75: 5570-4. PMID 103097 DOI: 10.1073/Pnas.75.11.5570  0.315
1977 Garen A, Kauvar L, Lepesant JA. Roles of ecdysone in Drosophila development. Proceedings of the National Academy of Sciences of the United States of America. 74: 5099-103. PMID 16592466 DOI: 10.1073/Pnas.74.11.5099  0.345
1975 Rice TB, Garen A. Localized defects of blastoderm formation in maternal effect mutants of Drosophila. Developmental Biology. 43: 277-86. PMID 805069 DOI: 10.1016/0012-1606(75)90027-5  0.379
1974 Shearn A, Garen A. Genetic control of imaginal disc development in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 71: 1393-7. PMID 4208549 DOI: 10.1073/Pnas.71.4.1393  0.631
1972 Garen A, Gehring W. Repair of the lethal developmental defect in deep orange embryos of Drosophila by injection of normal egg cytoplasm. Proceedings of the National Academy of Sciences of the United States of America. 69: 2982-5. PMID 4628097 DOI: 10.1073/PNAS.69.10.2982  0.515
1971 Shearn A, Rice T, Garen A, Gehring W. Imaginal disc abnormalities in lethal mutants of Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 68: 2594-8. PMID 5002822 DOI: 10.1073/PNAS.68.10.2594  0.663
1970 Natori S, Garen A. Molecular heterogeneity in the amino-terminal region of alkaline phosphatase. Journal of Molecular Biology. 49: 577-88. PMID 4916549 DOI: 10.1016/0022-2836(70)90282-2  0.336
1970 Gopinathan KP, Garen A. A leucyl-transfer RNA specified by the amber suppressor gene Su6+. Journal of Molecular Biology. 47: 393-401. PMID 4907268 DOI: 10.1016/0022-2836(70)90310-4  0.326
1970 Chan TS, Garen A. Amino acid substitutions resulting from suppression of nonsense mutations. V. Tryptophan insertion by the Su9 gene, a suppressor of the UGA nonsense triplet. Journal of Molecular Biology. 49: 231-4. PMID 4317908 DOI: 10.1016/0022-2836(70)90388-8  0.401
1969 Suzuki T, Garen A. Fragments of alkaline phosphatase from nonsense mutants. I. Isolation and characterization of fragments from amber and ochre mutants. Journal of Molecular Biology. 45: 549-66. PMID 4917369 DOI: 10.1016/0022-2836(69)90312-X  0.36
1969 Chan TS, Garen A. Amino acid substitutions resulting from suppression of nonsense mutations. IV. Leucine insertion by the Su6+ suppressor gene. Journal of Molecular Biology. 45: 545-8. PMID 4917368 DOI: 10.1016/0022-2836(69)90311-8  0.424
1968 Garen A. Sense and nonsense in the genetic code. Three exceptional triplets can serve as both chain-terminating signals and amino acid codons. Science (New York, N.Y.). 160: 149-59. PMID 4868223 DOI: 10.1126/Science.160.3824.149  0.3
1967 Weigert MG, Lanka E, Garen A. Amino acid substitutions resulting from suppression of nonsense mutations. 3. Tyrosine insertion by the Su-4 gene. Journal of Molecular Biology. 23: 401-4. PMID 5340244 DOI: 10.1016/S0022-2836(67)80114-1  0.616
1967 Weigert MG, Lanka E, Garen A. Base composition of nonsense codons in Escherichia coli II. The N2 codon UAA. Journal of Molecular Biology. 23: 391-400. PMID 4292413 DOI: 10.1016/S0022-2836(67)80113-X  0.582
1966 Gallucci E, Garen A. Suppressor genes for nonsense mutations. II. The su-4 and su-5 suppressor genes of Escherichia coli. Journal of Molecular Biology. 15: 193-200. PMID 5330216 DOI: 10.1016/S0022-2836(66)80220-6  0.395
1966 Weigert MG, Gallucci E, Lanka E, Garen A. Characteristics of the genetic code in vivo. Cold Spring Harbor Symposia On Quantitative Biology. 31: 145-50. PMID 4866371 DOI: 10.1101/Sqb.1966.031.01.022  0.467
1965 WEIGERT MG, GAREN A. AMINO ACID SUBSTITUTIONS RESULTING FROM SUPPRESSION OF NONSENSE MUTATIONS. I. SERINE INSERTION BY THE SU-1 SUPPRESSOR GENE. Journal of Molecular Biology. 12: 448-55. PMID 14337506  0.58
1965 Garen A, Garen S, Wilhelm RC. Suppressor genes for nonsense mutations. I. The Su-1, Su-2 and Su-3 genes of Escherichia coli. Journal of Molecular Biology. 14: 167-78. PMID 5327650 DOI: 10.1016/S0022-2836(65)80238-8  0.422
1965 Weigert MG, Garen A. Base composition of nonsense codons in E. coli. Evidence from amino-acid substitutions at a tryptophan site in alkaline phosphatase. Nature. 206: 992-4. PMID 5320271 DOI: 10.1038/206992A0  0.547
1965 Weigert MG, Lanka E, Garen A. Amino acid substitutions resulting from suppression of nonsense mutations. II. Glutamine insertion by the Su-2 gene; tyrosine insertion by the Su-3 gene. Journal of Molecular Biology. 14: 522-7. PMID 4286570 DOI: 10.1016/S0022-2836(65)80201-7  0.614
1951 GAREN A, PUCK TT. The first two steps of the invasion of host cells by bacterial viruses. II. The Journal of Experimental Medicine. 94: 177-89. PMID 14861377 DOI: 10.1084/Jem.94.3.177  0.467
1951 PUCK TT, GAREN A, CLINE J. The mechanism of virus attachment to host cells. I. The role of ions in the primary reaction. The Journal of Experimental Medicine. 93: 65-88. PMID 14803632 DOI: 10.1084/Jem.93.1.65  0.451
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