Norbert Perrimon - Publications

Affiliations: 
1986- Genetics Harvard University, Cambridge, MA, United States 
Website:
https://perrimon.med.harvard.edu/

379 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ahmad M, He L, Perrimon N. Regulation of insulin and adipokinetic hormone/glucagon production in flies. Wiley Interdisciplinary Reviews. Developmental Biology. e360. PMID 31379062 DOI: 10.1002/wdev.360  0.68
2019 Zirin J, Ni X, Sack LM, Yang-Zhou D, Hu Y, Brathwaite R, Bulyk ML, Elledge SJ, Perrimon N. Interspecies analysis of MYC targets identifies tRNA synthetases as mediators of growth and survival in MYC-overexpressing cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31262815 DOI: 10.1073/pnas.1821863116  1
2019 He L, Binari R, Huang J, Falo-Sanjuan J, Perrimon N. study of gene expression with an enhanced dual-color fluorescent transcriptional timer. Elife. 8. PMID 31140975 DOI: 10.7554/eLife.46181  0.68
2019 Dumesic PA, Egan DF, Gut P, Tran MT, Parisi A, Chatterjee N, Jedrychowski M, Paschini M, Kazak L, Wilensky SE, Dou F, Bogoslavski D, Cartier JA, Perrimon N, Kajimura S, et al. An Evolutionarily Conserved uORF Regulates PGC1α and Oxidative Metabolism in Mice, Flies, and Bluefin Tuna. Cell Metabolism. PMID 31105043 DOI: 10.1016/j.cmet.2019.04.013  0.92
2019 Strumillo MJ, Oplová M, Viéitez C, Ochoa D, Shahraz M, Busby BP, Sopko R, Studer RA, Perrimon N, Panse VG, Beltrao P. Conserved phosphorylation hotspots in eukaryotic protein domain families. Nature Communications. 10: 1977. PMID 31036831 DOI: 10.1038/s41467-019-09952-x  0.36
2019 Hunter GL, He L, Perrimon N, Charras G, Giniger E, Baum B. A role for actomyosin contractility in Notch signaling. Bmc Biology. 17: 12. PMID 30744634 DOI: 10.1186/s12915-019-0625-9  0.68
2019 Xu C, Tang HW, Hung RJ, Hu Y, Ni X, Housden BE, Perrimon N. The Septate Junction Protein Tsp2A Restricts Intestinal Stem Cell Activity via Endocytic Regulation of aPKC and Hippo Signaling. Cell Reports. 26: 670-688.e6. PMID 30650359 DOI: 10.1016/j.celrep.2018.12.079  1
2019 Song W, Kir S, Hong S, Hu Y, Wang X, Binari R, Tang HW, Chung V, Banks AS, Spiegelman B, Perrimon N. Tumor-Derived Ligands Trigger Tumor Growth and Host Wasting via Differential MEK Activation. Developmental Cell. PMID 30639055 DOI: 10.1016/j.devcel.2018.12.003  1
2018 He L, Ahmad M, Perrimon N. Mechanosensitive channels and their functions in stem cell differentiation. Experimental Cell Research. PMID 30500393 DOI: 10.1016/j.yexcr.2018.11.016  0.68
2018 Parasram K, Bernardon N, Hammoud M, Chang H, He L, Perrimon N, Karpowicz P. Intestinal Stem Cells Exhibit Conditional Circadian Clock Function. Stem Cell Reports. 11: 1287-1301. PMID 30428387 DOI: 10.1016/j.stemcr.2018.10.010  1
2018 Doupé DP, Marshall OJ, Dayton H, Brand AH, Perrimon N. intestinal stem and progenitor cells are major sources and regulators of homeostatic niche signals. Proceedings of the National Academy of Sciences of the United States of America. PMID 30404917 DOI: 10.1073/pnas.1719169115  0.96
2018 Hu Y, Sopko R, Chung V, Foos M, Studer RA, Landry SD, Liu D, Rabinow L, Gnad F, Beltrao P, Perrimon N. iProteinDB: An Integrative Database of Post-translational Modifications. G3 (Bethesda, Md.). PMID 30397019 DOI: 10.1534/g3.118.200637  1
2018 Okamoto N, Viswanatha R, Bittar R, Li Z, Haga-Yamanaka S, Perrimon N, Yamanaka N. A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila. Developmental Cell. PMID 30293839 DOI: 10.1016/j.devcel.2018.09.012  0.64
2018 Song W, Ghosh AC, Cheng D, Perrimon N. Endocrine Regulation of Energy Balance by Drosophila TGF-β/Activins. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 30264417 DOI: 10.1002/bies.201800044  0.64
2018 Branon TC, Bosch JA, Sanchez AD, Udeshi ND, Svinkina T, Carr SA, Feldman JL, Perrimon N, Ting AY. Efficient proximity labeling in living cells and organisms with TurboID. Nature Biotechnology. PMID 30125270 DOI: 10.1038/nbt.4201  0.4
2018 Viswanatha R, Li Z, Hu Y, Perrimon N. Pooled genome-wide CRISPR screening for basal and context-specific fitness gene essentiality in cells. Elife. 7. PMID 30051818 DOI: 10.7554/eLife.36333  1
2018 Ewen-Campen B, Perrimon N. Co-selection: A Method for Enriching CRISPR/Cas9-Edited Alleles in . G3 (Bethesda, Md.). PMID 29934375 DOI: 10.1534/g3.118.200498  1
2018 Jia Y, Xu RG, Ren X, Ewen-Campen B, Rajakumar R, Zirin J, Yang-Zhou D, Zhu R, Wang F, Mao D, Peng P, Qiao HH, Wang X, Liu LP, Xu B, ... ... Perrimon N, et al. Next-generation CRISPR/Cas9 transcriptional activation in using flySAM. Proceedings of the National Academy of Sciences of the United States of America. PMID 29666231 DOI: 10.1073/pnas.1800677115  1
2018 Hong S, Song W, Zushin PH, Liu B, Jedrychowski MP, Mina AI, Deng Z, Cabarkapa D, Hall JA, Palmer CJ, Aliakbarian H, Szpyt J, Gygi SP, Tavakkoli A, Lynch L, ... Perrimon N, et al. Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes. Molecular Metabolism. PMID 29661693 DOI: 10.1016/j.molmet.2018.03.012  0.56
2018 Tang HW, Hu Y, Chen CL, Xia B, Zirin J, Yuan M, Asara JM, Rabinow L, Perrimon N. The TORC1-Regulated CPA Complex Rewires an RNA Processing Network to Drive Autophagy and Metabolic Reprogramming. Cell Metabolism. PMID 29606597 DOI: 10.1016/j.cmet.2018.02.023  1
2018 Zhang T, Song W, Li Z, Qian W, Wei L, Yang Y, Wang W, Zhou X, Meng M, Peng J, Xia Q, Perrimon N, Cheng D. Krüppel homolog 1 represses insect ecdysone biosynthesis by directly inhibiting the transcription of steroidogenic enzymes. Proceedings of the National Academy of Sciences of the United States of America. PMID 29567866 DOI: 10.1073/pnas.1800435115  0.64
2018 Lee PT, Zirin J, Kanca O, Lin WW, Schulze KL, Li-Kroeger D, Tao R, Devereaux C, Hu Y, Chung V, Fang Y, He Y, Pan H, Ge M, Zuo Z, ... ... Perrimon N, et al. A gene-specificlibrary for. Elife. 7. PMID 29565247 DOI: 10.7554/eLife.35574  1
2018 Guo J, Tang HW, Li J, Perrimon N, Yan D. Xio is a component of thesex determination pathway and RNA-methyladenosine methyltransferase complex. Proceedings of the National Academy of Sciences of the United States of America. PMID 29555755 DOI: 10.1073/pnas.1720945115  1
2018 He L, Si G, Huang J, Samuel ADT, Perrimon N. Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channel. Nature. PMID 29414942 DOI: 10.1038/nature25744  0.68
2017 Mohr SE, Rudd K, Hu Y, Song WR, Gilly Q, Buckner M, Housden BE, Kelley C, Zirin J, Tao R, Amador G, Sierzputowska K, Comjean A, Perrimon N. Zinc Detoxification: A Functional Genomics and Transcriptomics Analysis in Drosophila melanogaster Cultured Cells. G3 (Bethesda, Md.). PMID 29223976 DOI: 10.1534/g3.117.300447  1
2017 Housden BE, Li Z, Kelley C, Wang Y, Hu Y, Valvezan AJ, Manning BD, Perrimon N. Improved detection of synthetic lethal interactions in Drosophila cells using variable dose analysis (VDA). Proceedings of the National Academy of Sciences of the United States of America. 114: E10755-E10762. PMID 29183982 DOI: 10.1073/pnas.1713362114  1
2017 Hu Y, Vinayagam A, Nand A, Comjean A, Chung V, Hao T, Mohr SE, Perrimon N. Molecular Interaction Search Tool (MIST): an integrated resource for mining gene and protein interaction data. Nucleic Acids Research. PMID 29155944 DOI: 10.1093/nar/gkx1116  1
2017 Valvezan AJ, Turner M, Belaid A, Lam HC, Miller SK, McNamara MC, Baglini C, Housden BE, Perrimon N, Kwiatkowski DJ, Asara JM, Henske EP, Manning BD. mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability. Cancer Cell. PMID 29056426 DOI: 10.1016/j.ccell.2017.09.013  0.72
2017 Rajan A, Housden BE, Wirtz-Peitz F, Holderbaum L, Perrimon N. A Mechanism Coupling Systemic Energy Sensing to Adipokine Secretion. Developmental Cell. 43: 83-98.e6. PMID 29017032 DOI: 10.1016/j.devcel.2017.09.007  0.96
2017 Ewen-Campen B, Mohr SE, Hu Y, Perrimon N. Accessing the Phenotype Gap: Enabling Systematic Investigation of Paralog Functional Complexity with CRISPR. Developmental Cell. 43: 6-9. PMID 29017030 DOI: 10.1016/j.devcel.2017.09.020  1
2017 Ewen-Campen B, Yang-Zhou D, Fernandes VR, González DP, Liu LP, Tao R, Ren X, Sun J, Hu Y, Zirin J, Mohr SE, Ni JQ, Perrimon N. Optimized strategy for in vivo Cas9-activation in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. PMID 28808002 DOI: 10.1073/pnas.1707635114  1
2017 Song W, Owusu-Ansah E, Hu Y, Cheng D, Ni X, Zirin J, Perrimon N. Activin signaling mediates muscle-to-adipose communication in a mitochondria dysfunction-associated obesity model. Proceedings of the National Academy of Sciences of the United States of America. PMID 28739899 DOI: 10.1073/pnas.1708037114  1
2017 Lee HJ, Jedrychowski MP, Vinayagam A, Wu N, Shyh-Chang N, Hu Y, Min-Wen C, Moore JK, Asara JM, Lyssiotis CA, Perrimon N, Gygi SP, Cantley LC, Kirschner MW. Proteomic and Metabolomic Characterization of a Mammalian Cellular Transition from Quiescence to Proliferation. Cell Reports. 20: 721-736. PMID 28723573 DOI: 10.1016/j.celrep.2017.06.074  1
2017 Hu Y, Comjean A, Mohr SE, FlyBase Consortium T, Perrimon N. Gene2Function: An Integrated Online Resource for Gene Function Discovery. G3 (Bethesda, Md.). PMID 28663344 DOI: 10.1534/g3.117.043885  1
2017 Xu C, Luo J, He L, Montell C, Perrimon N. Oxidative stress induces stem cell proliferation via TRPA1/RyR-mediated Ca(2+) signaling in the Drosophila midgut. Elife. 6. PMID 28561738 DOI: 10.7554/eLife.22441  0.68
2017 Housden BE, Nicholson HE, Perrimon N. Synthetic Lethality Screens Using RNAi in Combination with CRISPR-based Knockout in Drosophila Cells. Bio-Protocol. 7. PMID 28523286 DOI: 10.21769/BioProtoc.2119  0.72
2017 Wang J, Al-Ouran R, Hu Y, Kim SY, Wan YW, Wangler MF, Yamamoto S, Chao HT, Comjean A, Mohr SE, Perrimon N, Liu Z, Bellen HJ. MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome. American Journal of Human Genetics. PMID 28502612 DOI: 10.1016/j.ajhg.2017.04.010  1
2017 He L, Huang J, Perrimon N. Development of an optimized synthetic Notch receptor as an in vivo cell-cell contact sensor. Proceedings of the National Academy of Sciences of the United States of America. PMID 28490499 DOI: 10.1073/pnas.1703205114  0.68
2017 Chatterjee N, Perrimon N. Thermogenesis by THADA. Developmental Cell. 41: 1-2. PMID 28399393 DOI: 10.1016/j.devcel.2017.03.021  0.92
2017 Chen CL, Perrimon N. Proximity-dependent labeling methods for proteomic profiling in living cells. Wiley Interdisciplinary Reviews. Developmental Biology. PMID 28387482 DOI: 10.1002/wdev.272  0.4
2017 Hu Y, Comjean A, Perrimon N, Mohr SE. The Drosophila Gene Expression Tool (DGET) for expression analyses. Bmc Bioinformatics. 18: 98. PMID 28187709 DOI: 10.1186/s12859-017-1509-z  0.64
2017 Song W, Cheng D, Hong S, Sappe B, Hu Y, Wei N, Zhu C, O'Connor MB, Pissios P, Perrimon N. Midgut-Derived Activin Regulates Glucagon-like Action in the Fat Body and Glycemic Control. Cell Metabolism. 25: 386-399. PMID 28178568 DOI: 10.1016/j.cmet.2017.01.002  1
2016 Hu Y, Comjean A, Roesel C, Vinayagam A, Flockhart I, Zirin J, Perkins L, Perrimon N, Mohr SE. FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2017 update. Nucleic Acids Research. PMID 27924039 DOI: 10.1093/nar/gkw977  1
2016 Housden BE, Muhar M, Gemberling M, Gersbach CA, Stainier DY, Seydoux G, Mohr SE, Zuber J, Perrimon N. Loss-of-function genetic tools for animal models: cross-species and cross-platform differences. Nature Reviews. Genetics. PMID 27795562 DOI: 10.1038/nrg.2016.118  1
2016 Droujinine IA, Perrimon N. Interorgan Communication Pathways in Physiology: Focus on Drosophila. Annual Review of Genetics. PMID 27732790 DOI: 10.1146/annurev-genet-121415-122024  0.64
2016 Vinayagam A, Kulkarni MM, Sopko R, Sun X, Hu Y, Nand A, Villalta C, Moghimi A, Yang X, Mohr SE, Hong P, Asara JM, Perrimon N. An Integrative Analysis of the InR/PI3K/Akt Network Identifies the Dynamic Response to Insulin Signaling. Cell Reports. 16: 3062-3074. PMID 27626673 DOI: 10.1016/j.celrep.2016.08.029  1
2016 Housden BE, Perrimon N. Cas9-Mediated Genome Engineering in Drosophila melanogaster. Cold Spring Harbor Protocols. 2016: pdb.top086843. PMID 27587786 DOI: 10.1101/pdb.top086843  0.72
2016 Housden BE, Perrimon N. Detection of Indel Mutations in Drosophila by High-Resolution Melt Analysis (HRMA). Cold Spring Harbor Protocols. 2016: pdb.prot090795. PMID 27587781 DOI: 10.1101/pdb.prot090795  0.72
2016 Housden BE, Perrimon N. Design and Generation of Donor Constructs for Genome Engineering in Drosophila. Cold Spring Harbor Protocols. 2016: pdb.prot090787. PMID 27587780 DOI: 10.1101/pdb.prot090787  0.72
2016 Housden BE, Hu Y, Perrimon N. Design and Generation of Drosophila Single Guide RNA Expression Constructs. Cold Spring Harbor Protocols. 2016: pdb.prot090779. PMID 27587779 DOI: 10.1101/pdb.prot090779  1
2016 Wang H, Becuwe M, Housden BE, Chitraju C, Porras AJ, Graham MM, Liu XN, Thiam AR, Savage DB, Agarwal AK, Garg A, Olarte MJ, Lin Q, Fröhlich F, Hannibal-Bach HK, ... ... Perrimon N, et al. Seipin is required for converting nascent to mature lipid droplets. Elife. 5. PMID 27564575 DOI: 10.7554/eLife.16582  0.32
2016 Ammeux N, Housden BE, Georgiadis A, Hu Y, Perrimon N. Mapping signaling pathway cross-talk in Drosophila cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27528688 DOI: 10.1073/pnas.1610432113  1
2016 Petsakou A, Perrimon N. "ISN't Thirst Sweet?" Says the Fly. Cell. 166: 796-7. PMID 27518557 DOI: 10.1016/j.cell.2016.07.038  1
2016 Parkhitko AA, Binari R, Zhang N, Asara JM, Demontis F, Perrimon N. Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila. Genes & Development. PMID 27313316 DOI: 10.1101/gad.282277.116  0.48
2016 Housden BE, Perrimon N. Comparing CRISPR and RNAi-based screening technologies. Nature Biotechnology. 34: 621-3. PMID 27281421 DOI: 10.1038/nbt.3599  0.72
2016 Mohr SE, Hu Y, Ewen-Campen B, Housden BE, Viswanatha R, Perrimon N. CRISPR guide RNA design for research applications. The Febs Journal. PMID 27276584 DOI: 10.1111/febs.13777  1
2016 Hunter GL, Hadjivasiliou Z, Bonin H, He L, Perrimon N, Charras G, Baum B. Coordinated control of Notch-Delta signalling and cell cycle progression drives lateral inhibition mediated tissue patterning. Development (Cambridge, England). PMID 27226324 DOI: 10.1242/dev.134213  0.68
2016 Harris KP, Zhang YV, Piccioli ZD, Perrimon N, Littleton JT. The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling. Elife. 5. PMID 27223326 DOI: 10.7554/eLife.13881  0.32
2016 Chavez A, Tuttle M, Pruitt BW, Ewen-Campen B, Chari R, Ter-Ovanesyan D, Haque SJ, Cecchi RJ, Kowal EJ, Buchthal J, Housden BE, Perrimon N, Collins JJ, Church G. Comparison of Cas9 activators in multiple species. Nature Methods. PMID 27214048 DOI: 10.1038/nmeth.3871  1
2016 Vinayagam A, Gibson TE, Lee HJ, Yilmazel B, Roesel C, Hu Y, Kwon Y, Sharma A, Liu YY, Perrimon N, Barabási AL. Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets. Proceedings of the National Academy of Sciences of the United States of America. PMID 27091990 DOI: 10.1073/pnas.1603992113  1
2016 Doupé DP, Perrimon N. Toward a Systems Understanding of Signaling Pathway Function. Current Topics in Developmental Biology. 117: 221-36. PMID 26969980 DOI: 10.1016/bs.ctdb.2015.11.005  0.56
2016 Perrimon N, Bonini NM, Dhillon P. Fruit flies on the front line: the translational impact of Drosophila. Disease Models & Mechanisms. 9: 229-31. PMID 26935101 DOI: 10.1242/dmm.024810  1
2016 Ma M, Zhao H, Zhao H, Binari R, Perrimon N, Li Z. Wildtype adult stem cells, unlike tumor cells, are resistant to cellular damages in Drosophila. Developmental Biology. PMID 26845534 DOI: 10.1016/j.ydbio.2016.01.040  0.32
2016 Breitkopf SB, Yang X, Begley MJ, Kulkarni M, Chiu YH, Turke AB, Lauriol J, Yuan M, Qi J, Engelman JA, Hong P, Kontaridis MI, Cantley LC, Perrimon N, Asara JM. A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2. Scientific Reports. 6: 20471. PMID 26839216 DOI: 10.1038/srep20471  0.32
2015 Jodoin JN, Coravos JS, Chanet S, Vasquez CG, Tworoger M, Kingston ER, Perkins LA, Perrimon N, Martin AC. Stable Force Balance between Epithelial Cells Arises from F-Actin Turnover. Developmental Cell. PMID 26688336 DOI: 10.1016/j.devcel.2015.11.018  0.56
2015 Dequéant ML, Fagegaltier D, Hu Y, Spirohn K, Simcox A, Hannon GJ, Perrimon N. Discovery of progenitor cell signatures by time-series synexpression analysis during Drosophila embryonic cell immortalization. Proceedings of the National Academy of Sciences of the United States of America. PMID 26438832 DOI: 10.1073/pnas.1517729112  1
2015 Kuhn H, Sopko R, Coughlin M, Perrimon N, Mitchison T. The Atg1-Tor pathway regulates yolk catabolism in Drosophila embryos. Development (Cambridge, England). PMID 26395483 DOI: 10.1242/dev.125419  0.36
2015 Owusu-Ansah E, Perrimon N. Stress Signaling Between Organs in Metazoa. Annual Review of Cell and Developmental Biology. PMID 26393775 DOI: 10.1146/annurev-cellbio-100814-125523  1
2015 Chen CL, Hu Y, Udeshi ND, Lau TY, Wirtz-Peitz F, He L, Ting AY, Carr SA, Perrimon N. Proteomic mapping in live Drosophila tissues using an engineered ascorbate peroxidase. Proceedings of the National Academy of Sciences of the United States of America. PMID 26362788 DOI: 10.1073/pnas.1515623112  1
2015 Housden BE, Valvezan AJ, Kelley C, Sopko R, Hu Y, Roesel C, Lin S, Buckner M, Tao R, Yilmazel B, Mohr SE, Manning BD, Perrimon N. Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi. Science Signaling. 8: rs9. PMID 26350902 DOI: 10.1126/scisignal.aab3729  1
2015 Yan D, Perrimon N. spenito is required for sex determination in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 112: 11606-11. PMID 26324914 DOI: 10.1073/pnas.1515891112  1
2015 Perkins LA, Holderbaum L, Tao R, Hu Y, Sopko R, McCall K, Yang-Zhou D, Flockhart I, Binari R, Shim HS, Miller A, Housden A, Foos M, Randkelv S, Kelley C, ... ... Perrimon N, et al. The Transgenic RNAi Project at Harvard Medical School: Resources and Validation. Genetics. PMID 26320097 DOI: 10.1534/genetics.115.180208  1
2015 Lin S, Ewen-Campen B, Ni X, Housden BE, Perrimon N. In Vivo Transcriptional Activation Using CRISPR-Cas9 in Drosophila. Genetics. PMID 26245833 DOI: 10.1534/genetics.115.181065  1
2015 Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, ... ... Perrimon N, et al. BIOSAFETY. Safeguarding gene drive experiments in the laboratory. Science (New York, N.Y.). 349: 927-9. PMID 26229113 DOI: 10.1126/science.aac7932  0.56
2015 Mohr SE, Hu Y, Rudd K, Buckner M, Gilly Q, Foster B, Sierzputowska K, Comjean A, Ye B, Perrimon N. Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells. G3 (Bethesda, Md.). PMID 26199285 DOI: 10.1534/g3.115.019364  1
2015 Hu Y, Comjean A, Perkins LA, Perrimon N, Mohr SE. GLAD: an Online Database of Gene List Annotation for Drosophila. Journal of Genomics. 3: 75-81. PMID 26157507 DOI: 10.7150/jgen.12863  1
2015 Fulga TA, McNeill EM, Binari R, Yelick J, Blanche A, Booker M, Steinkraus BR, Schnall-Levin M, Zhao Y, DeLuca T, Bejarano F, Han Z, Lai EC, Wall DP, Perrimon N, et al. A transgenic resource for conditional competitive inhibition of conserved Drosophila microRNAs. Nature Communications. 6: 7279. PMID 26081261 DOI: 10.1038/ncomms8279  1
2015 Gordon WR, Zimmerman B, He L, Miles LJ, Huang J, Tiyanont K, McArthur DG, Aster JC, Perrimon N, Loparo JJ, Blacklow SC. Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch. Developmental Cell. 33: 729-36. PMID 26051539 DOI: 10.1016/j.devcel.2015.05.004  1
2015 Kwon Y, Song W, Droujinine IA, Hu Y, Asara JM, Perrimon N. Systemic organ wasting induced by localized expression of the secreted insulin/IGF antagonist ImpL2. Developmental Cell. 33: 36-46. PMID 25850671 DOI: 10.1016/j.devcel.2015.02.012  1
2015 Sopko R, Lin YB, Makhijani K, Alexander B, Perrimon N, Brückner K. A systems-level interrogation identifies regulators of Drosophila blood cell number and survival. Plos Genetics. 11: e1005056. PMID 25749252 DOI: 10.1371/journal.pgen.1005056  1
2015 Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, P R Iyer E, Lin S, Kiani S, Guzman CD, Wiegand DJ, Ter-Ovanesyan D, Braff JL, Davidsohn N, Housden BE, Perrimon N, et al. Highly efficient Cas9-mediated transcriptional programming. Nature Methods. 12: 326-8. PMID 25730490 DOI: 10.1038/nmeth.3312  0.72
2015 Zirin J, Nieuwenhuis J, Samsonova A, Tao R, Perrimon N. Regulators of autophagosome formation in Drosophila muscles. Plos Genetics. 11: e1005006. PMID 25692684 DOI: 10.1371/journal.pgen.1005006  1
2015 Leshchiner ES, Parkhitko A, Bird GH, Luccarelli J, Bellairs JA, Escudero S, Opoku-Nsiah K, Godes M, Perrimon N, Walensky LD. Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices. Proceedings of the National Academy of Sciences of the United States of America. 112: 1761-6. PMID 25624485 DOI: 10.1073/pnas.1413185112  1
2015 Sun X, Mohr S, Vinayagam A, Hong P, Perrimon N. Inferring genetic architecture from systems genetics studies Systems Genetics: Linking Genotypes and Phenotypes. 139-160. DOI: 10.1017/CBO9781139012751.008  0.6
2014 Housden BE, Lin S, Perrimon N. Cas9-based genome editing in Drosophila. Methods in Enzymology. 546: 415-39. PMID 25398351 DOI: 10.1016/B978-0-12-801185-0.00019-2  1
2014 Sopko R, Foos M, Vinayagam A, Zhai B, Binari R, Hu Y, Randklev S, Perkins LA, Gygi SP, Perrimon N. Combining genetic perturbations and proteomics to examine kinase-phosphatase networks in Drosophila embryos. Developmental Cell. 31: 114-27. PMID 25284370 DOI: 10.1016/j.devcel.2014.07.027  1
2014 Droujinine IA, Yan D, Perrimon N. A sharp end to sugary Wingless travels. The Journal of Cell Biology. 206: 819-21. PMID 25267292 DOI: 10.1083/jcb.201408115  1
2014 Song W, Veenstra JA, Perrimon N. Control of lipid metabolism by tachykinin in Drosophila. Cell Reports. 9: 40-7. PMID 25263556 DOI: 10.1016/j.celrep.2014.08.060  1
2014 Amcheslavsky A, Song W, Li Q, Nie Y, Bragatto I, Ferrandon D, Perrimon N, Ip YT. Enteroendocrine cells support intestinal stem-cell-mediated homeostasis in Drosophila. Cell Reports. 9: 32-9. PMID 25263551 DOI: 10.1016/j.celrep.2014.08.052  1
2014 Gerstein MB, Rozowsky J, Yan KK, Wang D, Cheng C, Brown JB, Davis CA, Hillier L, Sisu C, Li JJ, Pei B, Harmanci AO, Duff MO, Djebali S, Alexander RP, ... ... Perrimon N, et al. Comparative analysis of the transcriptome across distant species. Nature. 512: 445-8. PMID 25164755 DOI: 10.1038/nature13424  1
2014 Housden BE, Perrimon N. Spatial and temporal organization of signaling pathways. Trends in Biochemical Sciences. 39: 457-64. PMID 25155749 DOI: 10.1016/j.tibs.2014.07.008  1
2014 Mohr SE, Smith JA, Shamu CE, Neumüller RA, Perrimon N. RNAi screening comes of age: improved techniques and complementary approaches. Nature Reviews. Molecular Cell Biology. 15: 591-600. PMID 25145850 DOI: 10.1038/nrm3860  1
2014 Yilmazel B, Hu Y, Sigoillot F, Smith JA, Shamu CE, Perrimon N, Mohr SE. Online GESS: prediction of miRNA-like off-target effects in large-scale RNAi screen data by seed region analysis. Bmc Bioinformatics. 15: 192. PMID 24934636 DOI: 10.1186/1471-2105-15-192  1
2014 Kim K, Vinayagam A, Perrimon N. A rapid genome-wide microRNA screen identifies miR-14 as a modulator of Hedgehog signaling. Cell Reports. 7: 2066-77. PMID 24931604 DOI: 10.1016/j.celrep.2014.05.025  1
2014 Perrimon N. Drosophila developmental biology methods. Methods (San Diego, Calif.). 68: 1. PMID 24908372 DOI: 10.1016/j.ymeth.2014.05.010  1
2014 Demontis F, Patel VK, Swindell WR, Perrimon N. Intertissue control of the nucleolus via a myokine-dependent longevity pathway. Cell Reports. 7: 1481-94. PMID 24882005 DOI: 10.1016/j.celrep.2014.05.001  1
2014 Zhou R, Mohr S, Hannon GJ, Perrimon N. Inducing RNAi in Drosophila cells by soaking with dsRNA. Cold Spring Harbor Protocols. 2014. PMID 24786505 DOI: 10.1101/pdb.prot080747  1
2014 Doupé DP, Perrimon N. Visualizing and manipulating temporal signaling dynamics with fluorescence-based tools. Science Signaling. 7: re1. PMID 24692594 DOI: 10.1126/scisignal.2005077  1
2014 Brown JB, Boley N, Eisman R, May GE, Stoiber MH, Duff MO, Booth BW, Wen J, Park S, Suzuki AM, Wan KH, Yu C, Zhang D, Carlson JW, Cherbas L, ... ... Perrimon N, et al. Diversity and dynamics of the Drosophila transcriptome. Nature. 512: 393-9. PMID 24670639 DOI: 10.1038/nature12962  1
2014 Mohr SE, Hu Y, Kim K, Housden BE, Perrimon N. Resources for functional genomics studies in Drosophila melanogaster. Genetics. 197: 1-18. PMID 24653003 DOI: 10.1534/genetics.113.154344  1
2014 Griffin R, Binari R, Perrimon N. Genetic odyssey to generate marked clones in Drosophila mosaics. Proceedings of the National Academy of Sciences of the United States of America. 111: 4756-63. PMID 24623854 DOI: 10.1073/pnas.1403218111  1
2014 Markstein M, Dettorre S, Cho J, Neumüller RA, Craig-Müller S, Perrimon N. Systematic screen of chemotherapeutics in Drosophila stem cell tumors. Proceedings of the National Academy of Sciences of the United States of America. 111: 4530-5. PMID 24616500 DOI: 10.1073/pnas.1401160111  1
2014 Owusu-Ansah E, Perrimon N. Modeling metabolic homeostasis and nutrient sensing in Drosophila: implications for aging and metabolic diseases. Disease Models & Mechanisms. 7: 343-50. PMID 24609035 DOI: 10.1242/dmm.012989  1
2014 Yan D, Neumüller RA, Buckner M, Ayers K, Li H, Hu Y, Yang-Zhou D, Pan L, Wang X, Kelley C, Vinayagam A, Binari R, Randklev S, Perkins LA, Xie T, ... ... Perrimon N, et al. A regulatory network of Drosophila germline stem cell self-renewal. Developmental Cell. 28: 459-73. PMID 24576427 DOI: 10.1016/j.devcel.2014.01.020  1
2014 Vinayagam A, Zirin J, Roesel C, Hu Y, Yilmazel B, Samsonova AA, Neumüller RA, Mohr SE, Perrimon N. Integrating protein-protein interaction networks with phenotypes reveals signs of interactions. Nature Methods. 11: 94-9. PMID 24240319 DOI: 10.1038/nmeth.2733  1
2014 Shulman JM, Imboywa S, Giagtzoglou N, Powers MP, Hu Y, Devenport D, Chipendo P, Chibnik LB, Diamond A, Perrimon N, Brown NH, De Jager PL, Feany MB. Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms. Human Molecular Genetics. 23: 870-7. PMID 24067533 DOI: 10.1093/hmg/ddt478  1
2014 Piccirillo R, Demontis F, Perrimon N, Goldberg AL. Mechanisms of muscle growth and atrophy in mammals and Drosophila. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 243: 201-15. PMID 24038488 DOI: 10.1002/dvdy.24036  1
2014 Tipping M, Perrimon N. Drosophila as a model for context-dependent tumorigenesis. Journal of Cellular Physiology. 229: 27-33. PMID 23836429 DOI: 10.1002/jcp.24427  1
2013 Sun X, Hong P, Kulkarni M, Kwon Y, Perrimon N. PPIRank - an advanced method for ranking protein-protein interations in TAP/MS data. Proteome Science. 11: S16. PMID 24565074 DOI: 10.1186/1477-5956-11-S1-S16  0.6
2013 Droujinine IA, Perrimon N. Defining the interorgan communication network: systemic coordination of organismal cellular processes under homeostasis and localized stress. Frontiers in Cellular and Infection Microbiology. 3: 82. PMID 24312902 DOI: 10.3389/fcimb.2013.00082  1
2013 Zirin J, Nieuwenhuis J, Perrimon N. Role of autophagy in glycogen breakdown and its relevance to chloroquine myopathy. Plos Biology. 11: e1001708. PMID 24265594 DOI: 10.1371/journal.pbio.1001708  1
2013 Owusu-Ansah E, Song W, Perrimon N. Muscle mitohormesis promotes longevity via systemic repression of insulin signaling. Cell. 155: 699-712. PMID 24243023 DOI: 10.1016/j.cell.2013.09.021  1
2013 Ren X, Sun J, Housden BE, Hu Y, Roesel C, Lin S, Liu LP, Yang Z, Mao D, Sun L, Wu Q, Ji JY, Xi J, Mohr SE, Xu J, ... Perrimon N, et al. Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9. Proceedings of the National Academy of Sciences of the United States of America. 110: 19012-7. PMID 24191015 DOI: 10.1073/pnas.1318481110  1
2013 Kwon Y, Vinayagam A, Sun X, Dephoure N, Gygi SP, Hong P, Perrimon N. The Hippo signaling pathway interactome. Science (New York, N.Y.). 342: 737-40. PMID 24114784 DOI: 10.1126/science.1243971  1
2013 Demontis F, Piccirillo R, Goldberg AL, Perrimon N. Mechanisms of skeletal muscle aging: insights from Drosophila and mammalian models. Disease Models & Mechanisms. 6: 1339-52. PMID 24092876 DOI: 10.1242/dmm.012559  1
2013 Xiong XP, Kurthkoti K, Chang KY, Lichinchi G, De N, Schneemann A, MacRae IJ, Rana TM, Perrimon N, Zhou R. Core small nuclear ribonucleoprotein particle splicing factor SmD1 modulates RNA interference in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 110: 16520-5. PMID 24067655 DOI: 10.1073/pnas.1315803110  1
2013 Zirin J, Cheng D, Dhanyasi N, Cho J, Dura JM, Vijayraghavan K, Perrimon N. Ecdysone signaling at metamorphosis triggers apoptosis of Drosophila abdominal muscles. Developmental Biology. 383: 275-84. PMID 24051228 DOI: 10.1016/j.ydbio.2013.08.029  1
2013 Neumüller RA, Gross T, Samsonova AA, Vinayagam A, Buckner M, Founk K, Hu Y, Sharifpoor S, Rosebrock AP, Andrews B, Winston F, Perrimon N. Conserved regulators of nucleolar size revealed by global phenotypic analyses. Science Signaling. 6: ra70. PMID 23962978 DOI: 10.1126/scisignal.2004145  1
2013 Hu Y, Sopko R, Foos M, Kelley C, Flockhart I, Ammeux N, Wang X, Perkins L, Perrimon N, Mohr SE. FlyPrimerBank: an online database for Drosophila melanogaster gene expression analysis and knockdown evaluation of RNAi reagents. G3 (Bethesda, Md.). 3: 1607-16. PMID 23893746 DOI: 10.1534/g3.113.007021  1
2013 Demontis F, Piccirillo R, Goldberg AL, Perrimon N. The influence of skeletal muscle on systemic aging and lifespan. Aging Cell. 12: 943-9. PMID 23802635 DOI: 10.1111/acel.12126  1
2013 Hu Y, Roesel C, Flockhart I, Perkins L, Perrimon N, Mohr SE. UP-TORR: online tool for accurate and Up-to-Date annotation of RNAi Reagents. Genetics. 195: 37-45. PMID 23792952 DOI: 10.1534/genetics.113.151340  1
2013 Yin Z, Sadok A, Sailem H, McCarthy A, Xia X, Li F, Garcia MA, Evans L, Barr AR, Perrimon N, Marshall CJ, Wong ST, Bakal C. A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes. Nature Cell Biology. 15: 860-71. PMID 23748611 DOI: 10.1038/ncb2764  1
2013 Silva-Ayala D, López T, Gutiérrez M, Perrimon N, López S, Arias CF. Genome-wide RNAi screen reveals a role for the ESCRT complex in rotavirus cell entry. Proceedings of the National Academy of Sciences of the United States of America. 110: 10270-5. PMID 23733942 DOI: 10.1073/pnas.1304932110  1
2013 Sopko R, Perrimon N. Receptor tyrosine kinases in Drosophila development. Cold Spring Harbor Perspectives in Biology. 5. PMID 23732470 DOI: 10.1101/cshperspect.a009050  1
2013 Zhou R, Mohr S, Hannon GJ, Perrimon N. Inducing RNAi in Drosophila cells by transfection with dsRNA. Cold Spring Harbor Protocols. 2013: 461-3. PMID 23637371 DOI: 10.1101/pdb.prot074351  1
2013 Rajan A, Perrimon N. Of flies and men: insights on organismal metabolism from fruit flies. Bmc Biology. 11: 38. PMID 23587196 DOI: 10.1186/1741-7007-11-38  1
2013 Karpowicz P, Zhang Y, Hogenesch JB, Emery P, Perrimon N. The circadian clock gates the intestinal stem cell regenerative state. Cell Reports. 3: 996-1004. PMID 23583176 DOI: 10.1016/j.celrep.2013.03.016  1
2013 Bergwitz C, Wee MJ, Sinha S, Huang J, DeRobertis C, Mensah LB, Cohen J, Friedman A, Kulkarni M, Hu Y, Vinayagam A, Schnall-Levin M, Berger B, Perkins LA, Mohr SE, ... Perrimon N, et al. Genetic determinants of phosphate response in Drosophila. Plos One. 8: e56753. PMID 23520455 DOI: 10.1371/journal.pone.0056753  1
2013 Vinayagam A, Hu Y, Kulkarni M, Roesel C, Sopko R, Mohr SE, Perrimon N. Protein complex-based analysis framework for high-throughput data sets. Science Signaling. 6: rs5. PMID 23443684 DOI: 10.1126/scisignal.2003629  1
2013 Roti G, Carlton A, Ross KN, Markstein M, Pajcini K, Su AH, Perrimon N, Pear WS, Kung AL, Blacklow SC, Aster JC, Stegmaier K. Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer. Cancer Cell. 23: 390-405. PMID 23434461 DOI: 10.1016/j.ccr.2013.01.015  1
2013 Pitsouli C, Perrimon N. The homeobox transcription factor cut coordinates patterning and growth during Drosophila airway remodeling. Science Signaling. 6: ra12. PMID 23423438 DOI: 10.1126/scisignal.2003424  1
2013 Yeh JT, Binari R, Gocha T, Dasgupta R, Perrimon N. PAPTi: a peptide aptamer interference toolkit for perturbation of protein-protein interaction networks. Scientific Reports. 3: 1156. PMID 23362456 DOI: 10.1038/srep01156  1
2013 Staller MV, Yan D, Randklev S, Bragdon MD, Wunderlich ZB, Tao R, Perkins LA, Depace AH, Perrimon N. Depleting gene activities in early Drosophila embryos with the "maternal-Gal4-shRNA" system. Genetics. 193: 51-61. PMID 23105012 DOI: 10.1534/genetics.112.144915  1
2013 Kulkarni MM, Perrimon N. Analyzing the Structure, Function and Information Flow in Signaling Networks using Quantitative Cellular Signatures Handbook of Systems Biology. 89-113. DOI: 10.1016/B978-0-12-385944-0.00005-8  1
2012 Rajan A, Perrimon N. Drosophila cytokine unpaired 2 regulates physiological homeostasis by remotely controlling insulin secretion. Cell. 151: 123-37. PMID 23021220 DOI: 10.1016/j.cell.2012.08.019  1
2012 Hosur R, Peng J, Vinayagam A, Stelzl U, Xu J, Perrimon N, Bienkowska J, Berger B. A computational framework for boosting confidence in high-throughput protein-protein interaction datasets. Genome Biology. 13: R76. PMID 22937800 DOI: 10.1186/gb-2012-13-8-r76  1
2012 Stender JD, Pascual G, Liu W, Kaikkonen MU, Do K, Spann NJ, Boutros M, Perrimon N, Rosenfeld MG, Glass CK. Control of proinflammatory gene programs by regulated trimethylation and demethylation of histone H4K20. Molecular Cell. 48: 28-38. PMID 22921934 DOI: 10.1016/j.molcel.2012.07.020  1
2012 Perrimon N, Pitsouli C, Shilo BZ. Signaling mechanisms controlling cell fate and embryonic patterning. Cold Spring Harbor Perspectives in Biology. 4: a005975. PMID 22855721 DOI: 10.1101/cshperspect.a005975  1
2012 Katewa SD, Demontis F, Kolipinski M, Hubbard A, Gill MS, Perrimon N, Melov S, Kapahi P. Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster. Cell Metabolism. 16: 97-103. PMID 22768842 DOI: 10.1016/j.cmet.2012.06.005  1
2012 Bejarano F, Bortolamiol-Becet D, Dai Q, Sun K, Saj A, Chou YT, Raleigh DR, Kim K, Ni JQ, Duan H, Yang JS, Fulga TA, Van Vactor D, Perrimon N, Lai EC. A genome-wide transgenic resource for conditional expression of Drosophila microRNAs. Development (Cambridge, England). 139: 2821-31. PMID 22745315 DOI: 10.1242/dev.079939  1
2012 Kusche-Gullberg M, Nybakken K, Perrimon N, Lindahl U. Drosophila heparan sulfate, a novel design. The Journal of Biological Chemistry. 287: 21950-6. PMID 22556423 DOI: 10.1074/jbc.M112.350389  1
2012 Bergwitz C, Rasmussen MD, DeRobertis C, Wee MJ, Sinha S, Chen HH, Huang J, Perrimon N. Roles of major facilitator superfamily transporters in phosphate response in Drosophila. Plos One. 7: e31730. PMID 22359624 DOI: 10.1371/journal.pone.0031730  1
2012 Neumüller RA, Wirtz-Peitz F, Lee S, Kwon Y, Buckner M, Hoskins RA, Venken KJ, Bellen HJ, Mohr SE, Perrimon N. Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes. Genetics. 190: 931-40. PMID 22174071 DOI: 10.1534/genetics.111.136465  1
2012 Flockhart IT, Booker M, Hu Y, McElvany B, Gilly Q, Mathey-Prevot B, Perrimon N, Mohr SE. FlyRNAi.org--the database of the Drosophila RNAi screening center: 2012 update. Nucleic Acids Research. 40: D715-9. PMID 22067456 DOI: 10.1093/nar/gkr953  1
2012 Mohr SE, Perrimon N. RNAi screening: new approaches, understandings, and organisms. Wiley Interdisciplinary Reviews. Rna. 3: 145-58. PMID 21953743 DOI: 10.1002/wrna.110  1
2012 Sun X, Hong P, Kulkarni M, Kwon Y, Perrimon N. An advanced method for identifying protein-protein interaction by analyzing TAP/MS data Proceedings - 2012 Ieee International Conference On Bioinformatics and Biomedicine, Bibm 2012. 250-255. DOI: 10.1109/BIBM.2012.6392678  1
2011 Perrimon N, Barkai N. The era of systems developmental biology. Current Opinion in Genetics & Development. 21: 681-3. PMID 22079435 DOI: 10.1016/j.gde.2011.10.004  1
2011 Friedman AA, Tucker G, Singh R, Yan D, Vinayagam A, Hu Y, Binari R, Hong P, Sun X, Porto M, Pacifico S, Murali T, Finley RL, Asara JM, Berger B, ... Perrimon N, et al. Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling. Science Signaling. 4: rs10. PMID 22028469 DOI: 10.1126/scisignal.2002029  1
2011 Rohn JL, Sims D, Liu T, Fedorova M, Schöck F, Dopie J, Vartiainen MK, Kiger AA, Perrimon N, Baum B. Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype. The Journal of Cell Biology. 194: 789-805. PMID 21893601 DOI: 10.1083/jcb.201103168  1
2011 Hu Y, Flockhart I, Vinayagam A, Bergwitz C, Berger B, Perrimon N, Mohr SE. An integrative approach to ortholog prediction for disease-focused and other functional studies. Bmc Bioinformatics. 12: 357. PMID 21880147 DOI: 10.1186/1471-2105-12-357  1
2011 Rajan A, Perrimon N. Drosophila as a model for interorgan communication: lessons from studies on energy homeostasis. Developmental Cell. 21: 29-31. PMID 21763605 DOI: 10.1016/j.devcel.2011.06.034  1
2011 Schnall-Levin M, Rissland OS, Johnston WK, Perrimon N, Bartel DP, Berger B. Unusually effective microRNA targeting within repeat-rich coding regions of mammalian mRNAs. Genome Research. 21: 1395-403. PMID 21685129 DOI: 10.1101/gr.121210.111  1
2011 Ni JQ, Zhou R, Czech B, Liu LP, Holderbaum L, Yang-Zhou D, Shim HS, Tao R, Handler D, Karpowicz P, Binari R, Booker M, Brennecke J, Perkins LA, Hannon GJ, ... Perrimon N, et al. A genome-scale shRNA resource for transgenic RNAi in Drosophila. Nature Methods. 8: 405-7. PMID 21460824 DOI: 10.1038/nmeth.1592  1
2011 Perrimon N, Zirin J, Bai J. Primary cell cultures from Drosophila gastrula embryos. Journal of Visualized Experiments : Jove. PMID 21403631 DOI: 10.3791/2215  1
2011 Chan WM, Tsoi H, Wu CC, Wong CH, Cheng TC, Li HY, Lau KF, Shaw PC, Perrimon N, Chan HY. Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1. Human Molecular Genetics. 20: 1738-50. PMID 21300695 DOI: 10.1093/hmg/ddr049  1
2011 Gibson WT, Veldhuis JH, Rubinstein B, Cartwright HN, Perrimon N, Brodland GW, Nagpal R, Gibson MC. Control of the mitotic cleavage plane by local epithelial topology. Cell. 144: 427-38. PMID 21295702 DOI: 10.1016/j.cell.2010.12.035  1
2011 Booker M, Samsonova AA, Kwon Y, Flockhart I, Mohr SE, Perrimon N. False negative rates in Drosophila cell-based RNAi screens: a case study. Bmc Genomics. 12: 50. PMID 21251254 DOI: 10.1186/1471-2164-12-50  1
2011 Kondo S, Perrimon N. A genome-wide RNAi screen identifies core components of the Gâ‚‚-M DNA damage checkpoint. Science Signaling. 4: rs1. PMID 21205937 DOI: 10.1126/scisignal.2001350  1
2011 Neumüller RA, Perrimon N. Where gene discovery turns into systems biology: genome-scale RNAi screens in Drosophila. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 3: 471-8. PMID 21197652 DOI: 10.1002/wsbm.127  1
2011 Graveley BR, Brooks AN, Carlson JW, Duff MO, Landolin JM, Yang L, Artieri CG, van Baren MJ, Boley N, Booth BW, Brown JB, Cherbas L, Davis CA, Dobin A, Li R, ... ... Perrimon N, et al. The developmental transcriptome of Drosophila melanogaster. Nature. 471: 473-9. PMID 21179090 DOI: 10.1038/nature09715  1
2011 Berezikov E, Robine N, Samsonova A, Westholm JO, Naqvi A, Hung JH, Okamura K, Dai Q, Bortolamiol-Becet D, Martin R, Zhao Y, Zamore PD, Hannon GJ, Marra MA, Weng Z, ... Perrimon N, et al. Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence. Genome Research. 21: 203-15. PMID 21177969 DOI: 10.1101/gr.116657.110  1
2011 Cherbas L, Willingham A, Zhang D, Yang L, Zou Y, Eads BD, Carlson JW, Landolin JM, Kapranov P, Dumais J, Samsonova A, Choi JH, Roberts J, Davis CA, Tang H, ... ... Perrimon N, et al. The transcriptional diversity of 25 Drosophila cell lines. Genome Research. 21: 301-14. PMID 21177962 DOI: 10.1101/gr.112961.110  1
2011 Micchelli CA, Sudmeier L, Perrimon N, Tang S, Beehler-Evans R. Identification of adult midgut precursors in Drosophila. Gene Expression Patterns : Gep. 11: 12-21. PMID 20804858 DOI: 10.1016/j.gep.2010.08.005  1
2011 Perrimon N. Deciphering Gene Expression Patterns Developmental Cell. 21: e1. DOI: 10.1016/j.devcel.2011.10.002  1
2010 Roy S, Ernst J, Kharchenko PV, Kheradpour P, Negre N, Eaton ML, Landolin JM, Bristow CA, Ma L, Lin MF, Washietl S, Arshinoff BI, Ay F, Meyer PE, ... ... Perrimon N, et al. Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (New York, N.Y.). 330: 1787-97. PMID 21177974 DOI: 10.1126/science.1198374  1
2010 Karpowicz P, Perrimon N. All for one, and one for all: the clonality of the intestinal stem cell niche. F1000 Biology Reports. 2: 73. PMID 21173846 DOI: 10.3410/B2-73  1
2010 Rui Y, Bai J, Perrimon N. Sarcomere formation occurs by the assembly of multiple latent protein complexes. Plos Genetics. 6: e1001208. PMID 21124995 DOI: 10.1371/journal.pgen.1001208  1
2010 Demontis F, Perrimon N. FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging. Cell. 143: 813-25. PMID 21111239 DOI: 10.1016/j.cell.2010.10.007  1
2010 Karpowicz P, Perez J, Perrimon N. The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration. Development (Cambridge, England). 137: 4135-45. PMID 21098564 DOI: 10.1242/dev.060483  1
2010 Pitsouli C, Perrimon N. Embryonic multipotent progenitors remodel the Drosophila airways during metamorphosis. Development (Cambridge, England). 137: 3615-24. PMID 20940225 DOI: 10.1242/dev.056408  1
2010 Zirin J, Perrimon N. Drosophila as a model system to study autophagy. Seminars in Immunopathology. 32: 363-72. PMID 20798940 DOI: 10.1007/s00281-010-0223-y  0.72
2010 Schnall-Levin M, Zhao Y, Perrimon N, Berger B. Conserved microRNA targeting in Drosophila is as widespread in coding regions as in 3'UTRs. Proceedings of the National Academy of Sciences of the United States of America. 107: 15751-6. PMID 20729470 DOI: 10.1073/pnas.1006172107  1
2010 Yan H, Venkatesan K, Beaver JE, Klitgord N, Yildirim MA, Hao T, Hill DE, Cusick ME, Perrimon N, Roth FP, Vidal M. A genome-wide gene function prediction resource for Drosophila melanogaster. Plos One. 5: e12139. PMID 20711346 DOI: 10.1371/journal.pone.0012139  1
2010 Rajan A, Perrimon N. Steroids make you bigger? Fat chance says Myc. Cell Metabolism. 12: 7-9. PMID 20620990 DOI: 10.1016/j.cmet.2010.06.003  1
2010 Kockel L, Kerr KS, Melnick M, Brückner K, Hebrok M, Perrimon N. Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling. Plos Genetics. 6: e1000990. PMID 20585550 DOI: 10.1371/journal.pgen.1000990  1
2010 Perrimon N, Ni JQ, Perkins L. In vivo RNAi: today and tomorrow. Cold Spring Harbor Perspectives in Biology. 2: a003640. PMID 20534712 DOI: 10.1101/cshperspect.a003640  1
2010 Bakal C, Perrimon N. Realizing the promise of RNAi high throughput screening. Developmental Cell. 18: 506-7. PMID 20412765 DOI: 10.1016/j.devcel.2010.04.005  1
2010 Mohr S, Bakal C, Perrimon N. Genomic screening with RNAi: results and challenges. Annual Review of Biochemistry. 79: 37-64. PMID 20367032 DOI: 10.1146/annurev-biochem-060408-092949  1
2010 Nir O, Bakal C, Perrimon N, Berger B. Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial RNAi screen. Genome Research. 20: 372-80. PMID 20144944 DOI: 10.1101/gr.100248.109  1
2010 Zhang S, Binari R, Zhou R, Perrimon N. A genomewide RNA interference screen for modifiers of aggregates formation by mutant Huntingtin in Drosophila. Genetics. 184: 1165-79. PMID 20100940 DOI: 10.1534/genetics.109.112516  1
2010 Lin C, Hong P, Bakal C, Perrimon N. Novel morphological phenotypes discovery in high-content screens using underused features 2nd International Conference On Bioinformatics and Computational Biology 2010, Bicob 2010. 184-189.  1
2009 Yang X, Friedman A, Nagpal S, Perrimon N, Asara JM. Use of a label-free quantitative platform based on MS/MS average TIC to calculate dynamics of protein complexes in insulin signaling. Journal of Biomolecular Techniques : Jbt. 20: 272-7. PMID 19949701  1
2009 Apidianakis Y, Pitsouli C, Perrimon N, Rahme L. Synergy between bacterial infection and genetic predisposition in intestinal dysplasia. Proceedings of the National Academy of Sciences of the United States of America. 106: 20883-8. PMID 19934041 DOI: 10.1073/pnas.0911797106  1
2009 Czech B, Zhou R, Erlich Y, Brennecke J, Binari R, Villalta C, Gordon A, Perrimon N, Hannon GJ. Hierarchical rules for Argonaute loading in Drosophila. Molecular Cell. 36: 445-56. PMID 19917252 DOI: 10.1016/j.molcel.2009.09.028  1
2009 Pitsouli C, Apidianakis Y, Perrimon N. Homeostasis in infected epithelia: stem cells take the lead. Cell Host & Microbe. 6: 301-7. PMID 19837370 DOI: 10.1016/j.chom.2009.10.001  1
2009 Bai J, Sepp KJ, Perrimon N. Culture of Drosophila primary cells dissociated from gastrula embryos and their use in RNAi screening. Nature Protocols. 4: 1502-12. PMID 19798083 DOI: 10.1038/nprot.2009.147  1
2009 Kondo S, Booker M, Perrimon N. Cross-species RNAi rescue platform in Drosophila melanogaster. Genetics. 183: 1165-73. PMID 19720858 DOI: 10.1534/genetics.109.106567  1
2009 Vinegoni C, Razansky D, Pitsouli C, Perrimon N, Ntziachristos V, Weissleder R. Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila. Journal of Visualized Experiments : Jove. PMID 19696720 DOI: 10.3791/1510  1
2009 Zhou R, Czech B, Brennecke J, Sachidanandam R, Wohlschlegel JA, Perrimon N, Hannon GJ. Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform. Rna (New York, N.Y.). 15: 1886-95. PMID 19635780 DOI: 10.1261/rna.1611309  1
2009 Griffin R, Sustar A, Bonvin M, Binari R, del Valle Rodriguez A, Hohl AM, Bateman JR, Villalta C, Heffern E, Grunwald D, Bakal C, Desplan C, Schubiger G, Wu CT, Perrimon N. The twin spot generator for differential Drosophila lineage analysis. Nature Methods. 6: 600-2. PMID 19633664 DOI: 10.1038/nmeth.1349  1
2009 Brouzes E, Medkova M, Savenelli N, Marran D, Twardowski M, Hutchison JB, Rothberg JM, Link DR, Perrimon N, Samuels ML. Droplet microfluidic technology for single-cell high-throughput screening. Proceedings of the National Academy of Sciences of the United States of America. 106: 14195-200. PMID 19617544 DOI: 10.1073/pnas.0903542106  1
2009 Kaplow IM, Singh R, Friedman A, Bakal C, Perrimon N, Berger B. RNAiCut: automated detection of significant genes from functional genomic screens. Nature Methods. 6: 476-7. PMID 19564846 DOI: 10.1038/nmeth0709-476  1
2009 Ni JQ, Liu LP, Binari R, Hardy R, Shim HS, Cavallaro A, Booker M, Pfeiffer BD, Markstein M, Wang H, Villalta C, Laverty TR, Perkins LA, Perrimon N. A Drosophila resource of transgenic RNAi lines for neurogenetics. Genetics. 182: 1089-100. PMID 19487563 DOI: 10.1534/genetics.109.103630  1
2009 Zhang S, Feany MB, Saraswati S, Littleton JT, Perrimon N. Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model. Disease Models & Mechanisms. 2: 247-66. PMID 19380309 DOI: 10.1242/dmm.000653  1
2009 Demontis F, Perrimon N. Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila. Development (Cambridge, England). 136: 983-93. PMID 19211682 DOI: 10.1242/dev.027466  1
2009 Wang J, Zhou X, Li F, Bradley PL, Chang SF, Perrimon N, Wong ST. An image score inference system for RNAi genome-wide screening based on fuzzy mixture regression modeling. Journal of Biomedical Informatics. 42: 32-40. PMID 18547870 DOI: 10.1016/j.jbi.2008.04.007  1
2009 Razansky D, Distel M, Vinegoni C, Ma R, Perrimon N, Köster RW, Ntziachristos V. Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo Nature Photonics. 3: 412-417. DOI: 10.1038/nphoton.2009.98  1
2008 Zhou R, Hotta I, Denli AM, Hong P, Perrimon N, Hannon GJ. Comparative analysis of argonaute-dependent small RNA pathways in Drosophila. Molecular Cell. 32: 592-9. PMID 19026789 DOI: 10.1016/j.molcel.2008.10.018  1
2008 Bakal C, Linding R, Llense F, Heffern E, Martin-Blanco E, Pawson T, Perrimon N. Phosphorylation networks regulating JNK activity in diverse genetic backgrounds. Science (New York, N.Y.). 322: 453-6. PMID 18927396 DOI: 10.1126/science.1158739  1
2008 Pitsouli C, Perrimon N. Developmental biology: Our fly cousins' gut. Nature. 454: 592-3. PMID 18668098 DOI: 10.1038/454592a  1
2008 Vincent S, Perrimon N, Axelrod JD. Hedgehog and Wingless stabilize but do not induce cell fate during Drosophila dorsal embryonic epidermal patterning. Development (Cambridge, England). 135: 2767-75. PMID 18614578 DOI: 10.1242/dev.017814  1
2008 Sepp KJ, Hong P, Lizarraga SB, Liu JS, Mejia LA, Walsh CA, Perrimon N. Identification of neural outgrowth genes using genome-wide RNAi. Plos Genetics. 4: e1000111. PMID 18604272 DOI: 10.1371/journal.pgen.1000111  1
2008 Yin Z, Zhou X, Bakal C, Li F, Sun Y, Perrimon N, Wong ST. Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens. Bmc Bioinformatics. 9: 264. PMID 18534020 DOI: 10.1186/1471-2105-9-264  1
2008 Czech B, Malone CD, Zhou R, Stark A, Schlingeheyde C, Dus M, Perrimon N, Kellis M, Wohlschlegel JA, Sachidanandam R, Hannon GJ, Brennecke J. An endogenous small interfering RNA pathway in Drosophila. Nature. 453: 798-802. PMID 18463631 DOI: 10.1038/nature07007  1
2008 Bai J, Binari R, Ni JQ, Vijayakanthan M, Li HS, Perrimon N. RNA interference screening in Drosophila primary cells for genes involved in muscle assembly and maintenance. Development (Cambridge, England). 135: 1439-49. PMID 18359903 DOI: 10.1242/dev.012849  1
2008 Markstein M, Pitsouli C, Villalta C, Celniker SE, Perrimon N. Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes. Nature Genetics. 40: 476-83. PMID 18311141 DOI: 10.1038/ng.101  1
2008 Philips JA, Porto MC, Wang H, Rubin EJ, Perrimon N. ESCRT factors restrict mycobacterial growth. Proceedings of the National Academy of Sciences of the United States of America. 105: 3070-5. PMID 18287038 DOI: 10.1073/pnas.0707206105  1
2008 Wang J, Zhou X, Bradley PL, Chang SF, Perrimon N, Wong ST. Cellular phenotype recognition for high-content RNA interference genome-wide screening. Journal of Biomolecular Screening. 13: 29-39. PMID 18227224 DOI: 10.1177/1087057107311223  1
2008 Ni JQ, Markstein M, Binari R, Pfeiffer B, Liu LP, Villalta C, Booker M, Perkins L, Perrimon N. Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. Nature Methods. 5: 49-51. PMID 18084299 DOI: 10.1038/nmeth1146  1
2008 Vinegoni C, Pitsouli C, Razansky D, Perrimon N, Ntziachristos V. In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography. Nature Methods. 5: 45-7. PMID 18066071 DOI: 10.1038/nmeth1149  1
2008 Baym M, Bakal C, Perrimon N, Berger B. High-resolution modeling of cellular signaling networks Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 4955: 257-271. DOI: 10.1007/978-3-540-78839-3_22  1
2007 Lin C, Mak W, Hong P, Sepp K, Perrimon N. Intelligent Interfaces for Mining Large-Scale RNAi-HCS Image Databases. Proceedings / Annual Ieee International Symposium On Bioinformatics and Bioengineering (Bibe). Ieee International Symposium On Bioinformatics and Bioengineering. 2007: 1333-1337. PMID 21278820 DOI: 10.1109/BIBE.2007.4375742  1
2007 Perrimon N, Mathey-Prevot B. Matter arising: off-targets and genome-scale RNAi screens in Drosophila. Fly. 1: 1-5. PMID 18705022  1
2007 Bai J, Hartwig JH, Perrimon N. SALS, a WH2-domain-containing protein, promotes sarcomeric actin filament elongation from pointed ends during Drosophila muscle growth. Developmental Cell. 13: 828-42. PMID 18061565 DOI: 10.1016/j.devcel.2007.10.003  1
2007 Leopold P, Perrimon N. Drosophila and the genetics of the internal milieu. Nature. 450: 186-8. PMID 17994083 DOI: 10.1038/nature06286  1
2007 Silver SJ, Hagen JW, Okamura K, Perrimon N, Lai EC. Functional screening identifies miR-315 as a potent activator of Wingless signaling. Proceedings of the National Academy of Sciences of the United States of America. 104: 18151-6. PMID 17989227 DOI: 10.1073/pnas.0706673104  1
2007 DasGupta R, Nybakken K, Booker M, Mathey-Prevot B, Gonsalves F, Changkakoty B, Perrimon N. A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila. Genome Biology. 8: R203. PMID 17903264 DOI: 10.1186/gb-2007-8-9-r203  1
2007 Ramadan N, Flockhart I, Booker M, Perrimon N, Mathey-Prevot B. Design and implementation of high-throughput RNAi screens in cultured Drosophila cells. Nature Protocols. 2: 2245-64. PMID 17853882 DOI: 10.1038/nprot.2007.250  1
2007 Bakal C, Aach J, Church G, Perrimon N. Quantitative morphological signatures define local signaling networks regulating cell morphology. Science (New York, N.Y.). 316: 1753-6. PMID 17588932 DOI: 10.1126/science.1140324  1
2007 Lu J, Ruhf ML, Perrimon N, Leder P. A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression. Proceedings of the National Academy of Sciences of the United States of America. 104: 9381-6. PMID 17517653 DOI: 10.1073/pnas.0610279104  1
2007 Mathey-Prevot B, Perrimon N. Do-it-yourself RNAi made easy? Nature Methods. 4: 308-9. PMID 17396126 DOI: 10.1038/nmeth0407-308  1
2007 Friedman A, Perrimon N. Genetic screening for signal transduction in the era of network biology. Cell. 128: 225-31. PMID 17254958 DOI: 10.1016/j.cell.2007.01.007  1
2007 Perrimon N, Mathey-Prevot B. Applications of high-throughput RNA interference screens to problems in cell and developmental biology. Genetics. 175: 7-16. PMID 17244760 DOI: 10.1534/genetics.106.069963  1
2007 Perrimon N, Friedman A, Mathey-Prevot B, Eggert US. Drug-target identification in Drosophila cells: combining high-throughout RNAi and small-molecule screens. Drug Discovery Today. 12: 28-33. PMID 17198970 DOI: 10.1016/j.drudis.2006.10.006  1
2007 Bach EA, Ekas LA, Ayala-Camargo A, Flaherty MS, Lee H, Perrimon N, Baeg GH. GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivo. Gene Expression Patterns : Gep. 7: 323-31. PMID 17008134 DOI: 10.1016/j.modgep.2006.08.003  1
2007 Yin Z, Zhou X, Bakal C, Li F, Sun Y, Perrimon N, Wong STC. Online phenotype discovery in high-content RNAi screens using gap statistics Aip Conference Proceedings. 952: 86-95. DOI: 10.1063/1.2816647  1
2006 Mathey-Prevot B, Perrimon N. Drosophila genome-wide RNAi screens: are they delivering the promise? Cold Spring Harbor Symposia On Quantitative Biology. 71: 141-8. PMID 17381290 DOI: 10.1101/sqb.2006.71.027  1
2006 Friedman A, Perrimon N. A functional RNAi screen for regulators of receptor tyrosine kinase and ERK signalling. Nature. 444: 230-4. PMID 17086199 DOI: 10.1038/nature05280  1
2006 Cherry S, Kunte A, Wang H, Coyne C, Rawson RB, Perrimon N. COPI activity coupled with fatty acid biosynthesis is required for viral replication. Plos Pathogens. 2: e102. PMID 17040126 DOI: 10.1371/journal.ppat.0020102  1
2006 Echeverri CJ, Beachy PA, Baum B, Boutros M, Buchholz F, Chanda SK, Downward J, Ellenberg J, Fraser AG, Hacohen N, Hahn WC, Jackson AL, Kiger A, Linsley PS, Lum L, ... ... Perrimon N, et al. Minimizing the risk of reporting false positives in large-scale RNAi screens. Nature Methods. 3: 777-9. PMID 16990807 DOI: 10.1038/nmeth1006-777  1
2006 Kulkarni MM, Booker M, Silver SJ, Friedman A, Hong P, Perrimon N, Mathey-Prevot B. Evidence of off-target effects associated with long dsRNAs in Drosophila melanogaster cell-based assays. Nature Methods. 3: 833-8. PMID 16964256 DOI: 10.1038/nmeth935  1
2006 Gibson MC, Patel AB, Nagpal R, Perrimon N. The emergence of geometric order in proliferating metazoan epithelia. Nature. 442: 1038-41. PMID 16900102 DOI: 10.1038/nature05014  1
2006 Friedman A, Perrimon N. High-throughput approaches to dissecting MAPK signaling pathways. Methods (San Diego, Calif.). 40: 262-71. PMID 16844385 DOI: 10.1016/j.ymeth.2006.05.002  1
2006 Chen LY, Wang JC, Hyvert Y, Lin HP, Perrimon N, Imler JL, Hsu JC. Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo. Current Biology : Cb. 16: 1183-93. PMID 16782008 DOI: 10.1016/j.cub.2006.05.050  1
2006 Echeverri CJ, Perrimon N. High-throughput RNAi screening in cultured cells: a user's guide. Nature Reviews. Genetics. 7: 373-84. PMID 16607398 DOI: 10.1038/nrg1836  1
2006 Bard F, Casano L, Mallabiabarrena A, Wallace E, Saito K, Kitayama H, Guizzunti G, Hu Y, Wendler F, Dasgupta R, Perrimon N, Malhotra V. Functional genomics reveals genes involved in protein secretion and Golgi organization. Nature. 439: 604-7. PMID 16452979 DOI: 10.1038/nature04377  1
2006 Flockhart I, Booker M, Kiger A, Boutros M, Armknecht S, Ramadan N, Richardson K, Xu A, Perrimon N, Mathey-Prevot B. FlyRNAi: the Drosophila RNAi screening center database. Nucleic Acids Research. 34: D489-94. PMID 16381918 DOI: 10.1093/nar/gkj114  1
2006 Micchelli CA, Perrimon N. Evidence that stem cells reside in the adult Drosophila midgut epithelium. Nature. 439: 475-9. PMID 16340959 DOI: 10.1038/nature04371  1
2006 Karsten P, Plischke I, Perrimon N, Zeidler MP. Mutational analysis reveals separable DNA binding and trans-activation of Drosophila STAT92E. Cellular Signalling. 18: 819-29. PMID 16129580 DOI: 10.1016/j.cellsig.2005.07.006  1
2006 Xiong G, Zhou X, Ji L, Bradley P, Perrimon N, Wong S. Segmentation of drosophila RNAi fluorescence images using level sets Proceedings - International Conference On Image Processing, Icip. 73-76. DOI: 10.1109/ICIP.2006.312365  1
2006 Brouzes E, Branciforte J, Twardowski M, Marran D, Suo Y, Charles Y, Boitard L, Weiner MP, Rothberg JM, Perrimon N, Link DR. Droplet-based high-throughput live/dead cell assay Micro Total Analysis Systems - Proceedings of Microtas 2006 Conference: 10th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 1043-1045.  1
2005 Zhou X, Liu KY, Bradley P, Perrimon N, Wong ST. Towards automated cellular image segmentation for RNAi genome-wide screening. Medical Image Computing and Computer-Assisted Intervention : Miccai ... International Conference On Medical Image Computing and Computer-Assisted Intervention. 8: 885-92. PMID 16685930  1
2005 Nybakken K, Vokes SA, Lin TY, McMahon AP, Perrimon N. A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway. Nature Genetics. 37: 1323-32. PMID 16311596 DOI: 10.1038/ng1682  1
2005 Kirilly D, Spana EP, Perrimon N, Padgett RW, Xie T. BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary. Developmental Cell. 9: 651-62. PMID 16256740 DOI: 10.1016/j.devcel.2005.09.013  1
2005 Häcker U, Nybakken K, Perrimon N. Heparan sulphate proteoglycans: the sweet side of development. Nature Reviews. Molecular Cell Biology. 6: 530-41. PMID 16072037 DOI: 10.1038/nrm1681  1
2005 Baeg GH, Zhou R, Perrimon N. Genome-wide RNAi analysis of JAK/STAT signaling components in Drosophila. Genes & Development. 19: 1861-70. PMID 16055650 DOI: 10.1101/gad.1320705  0.64
2005 Philips JA, Rubin EJ, Perrimon N. Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection. Science (New York, N.Y.). 309: 1251-3. PMID 16020694 DOI: 10.1126/science.1116006  1
2005 Agaisse H, Burrack LS, Philips JA, Rubin EJ, Perrimon N, Higgins DE. Genome-wide RNAi screen for host factors required for intracellular bacterial infection. Science (New York, N.Y.). 309: 1248-51. PMID 16020693 DOI: 10.1126/science.1116008  1
2005 Schober M, Rebay I, Perrimon N. Function of the ETS transcription factor Yan in border cell migration. Development (Cambridge, England). 132: 3493-504. PMID 16014514 DOI: 10.1242/dev.01911  1
2005 DasGupta R, Boutros M, Perrimon N. Drosophila Wnt/Fz pathways. Science's Stke : Signal Transduction Knowledge Environment. 2005: cm5. PMID 15886387 DOI: 10.1126/stke.2832005cm5  1
2005 DasGupta R, Kaykas A, Moon RT, Perrimon N. Functional genomic analysis of the Wnt-wingless signaling pathway. Science (New York, N.Y.). 308: 826-33. PMID 15817814 DOI: 10.1126/science.1109374  1
2005 Gibson MC, Perrimon N. Extrusion and death of DPP/BMP-compromised epithelial cells in the developing Drosophila wing. Science (New York, N.Y.). 307: 1785-9. PMID 15774762 DOI: 10.1126/science.1104751  0.96
2005 Cherry S, Doukas T, Armknecht S, Whelan S, Wang H, Sarnow P, Perrimon N. Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibition. Genes & Development. 19: 445-52. PMID 15713840 DOI: 10.1101/gad.1267905  1
2005 Armknecht S, Boutros M, Kiger A, Nybakken K, Mathey-Prevot B, Perrimon N. High-throughput RNA interference screens in Drosophila tissue culture cells. Methods in Enzymology. 392: 55-73. PMID 15644175 DOI: 10.1016/S0076-6879(04)92004-6  1
2004 Eggert US, Kiger AA, Richter C, Perlman ZE, Perrimon N, Mitchison TJ, Field CM. Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. Plos Biology. 2: e379. PMID 15547975 DOI: 10.1371/journal.pbio.0020379  1
2004 Baeg GH, Selva EM, Goodman RM, Dasgupta R, Perrimon N. The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycan receptors. Developmental Biology. 276: 89-100. PMID 15531366 DOI: 10.1016/j.ydbio.2004.08.023  1
2004 Schlesinger A, Kiger A, Perrimon N, Shilo BZ. Small wing PLCgamma is required for ER retention of cleaved Spitz during eye development in Drosophila. Developmental Cell. 7: 535-45. PMID 15469842 DOI: 10.1016/j.devcel.2004.09.001  1
2004 Sinenko SA, Kim EK, Wynn R, Manfruelli P, Ando I, Wharton KA, Perrimon N, Mathey-Prevot B. Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development. Developmental Biology. 273: 48-62. PMID 15302597 DOI: 10.1016/j.ydbio.2004.05.022  1
2004 Brückner K, Kockel L, Duchek P, Luque CM, Rørth P, Perrimon N. The PDGF/VEGF receptor controls blood cell survival in Drosophila. Developmental Cell. 7: 73-84. PMID 15239955 DOI: 10.1016/j.devcel.2004.06.007  1
2004 Agaisse H, Perrimon N. The roles of JAK/STAT signaling in Drosophila immune responses. Immunological Reviews. 198: 72-82. PMID 15199955 DOI: 10.1111/j.0105-2896.2004.0133.x  1
2004 Zeidler MP, Tan C, Bellaiche Y, Cherry S, Häder S, Gayko U, Perrimon N. Temperature-sensitive control of protein activity by conditionally splicing inteins. Nature Biotechnology. 22: 871-6. PMID 15184905 DOI: 10.1038/nbt979  1
2004 Perrimon N, Häcker U. Wingless, hedgehog and heparan sulfate proteoglycans. Development (Cambridge, England). 131: 2509-11; author repl. PMID 15148297 DOI: 10.1242/dev.01225  1
2004 Boutros M, Kiger AA, Armknecht S, Kerr K, Hild M, Koch B, Haas SA, Paro R, Perrimon N. Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science (New York, N.Y.). 303: 832-5. PMID 14764878 DOI: 10.1126/science.1091266  1
2004 Cherry S, Perrimon N. Entry is a rate-limiting step for viral infection in a Drosophila melanogaster model of pathogenesis. Nature Immunology. 5: 81-7. PMID 14691479 DOI: 10.1038/ni1019  1
2003 Bach EA, Vincent S, Zeidler MP, Perrimon N. A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway. Genetics. 165: 1149-66. PMID 14668372  1
2003 Gibson MC, Perrimon N. Apicobasal polarization: epithelial form and function. Current Opinion in Cell Biology. 15: 747-52. PMID 14644201  0.96
2003 Kiger AA, Baum B, Jones S, Jones MR, Coulson A, Echeverri C, Perrimon N. A functional genomic analysis of cell morphology using RNA interference. Journal of Biology. 2: 27. PMID 14527345 DOI: 10.1186/1475-4924-2-27  1
2003 Agaisse H, Petersen UM, Boutros M, Mathey-Prevot B, Perrimon N. Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury. Developmental Cell. 5: 441-50. PMID 12967563 DOI: 10.1016/S1534-5807(03)00244-2  1
2003 Sasamura T, Sasaki N, Miyashita F, Nakao S, Ishikawa HO, Ito M, Kitagawa M, Harigaya K, Spana E, Bilder D, Perrimon N, Matsuno K. neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase that is essential for Notch-Delta interactions. Development (Cambridge, England). 130: 4785-95. PMID 12917292 DOI: 10.1242/dev.00679  1
2003 Ghiglione C, Amundadottir L, Andresdottir M, Bilder D, Diamonti JA, Noselli S, Perrimon N, Carraway III KL. Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1. Development (Cambridge, England). 130: 4483-93. PMID 12900463 DOI: 10.1242/dev.00617  1
2003 Lüders F, Segawa H, Stein D, Selva EM, Perrimon N, Turco SJ, Häcker U. Slalom encodes an adenosine 3'-phosphate 5'-phosphosulfate transporter essential for development in Drosophila. The Embo Journal. 22: 3635-44. PMID 12853478 DOI: 10.1093/emboj/cdg345  1
2003 Bashirullah A, Pasquinelli AE, Kiger AA, Perrimon N, Ruvkun G, Thummel CS. Coordinate regulation of small temporal RNAs at the onset of Drosophila metamorphosis. Developmental Biology. 259: 1-8. PMID 12812783 DOI: 10.1016/S0012-1606(03)00063-0  1
2003 Adám G, Perrimon N, Noselli S. The retinoic-like juvenile hormone controls the looping of left-right asymmetric organs in Drosophila. Development (Cambridge, England). 130: 2397-406. PMID 12702654  0.44
2003 Schöck F, Perrimon N. Retraction of the Drosophila germ band requires cell-matrix interaction. Genes & Development. 17: 597-602. PMID 12629042 DOI: 10.1101/gad.1068403  1
2003 Nagy A, Perrimon N, Sandmeyer S, Plasterk R. Tailoring the genome: the power of genetic approaches. Nature Genetics. 33: 276-84. PMID 12610537 DOI: 10.1038/ng1115  1
2003 Bilder D, Schober M, Perrimon N. Integrated activity of PDZ protein complexes regulates epithelial polarity. Nature Cell Biology. 5: 53-8. PMID 12510194 DOI: 10.1038/ncb897  1
2003 Tan C, Stronach B, Perrimon N. Roles of myosin phosphatase during Drosophila development. Development (Cambridge, England). 130: 671-81. PMID 12505998 DOI: 10.1242/dev.00298  1
2003 Micchelli CA, Esler WP, Kimberly WT, Jack C, Berezovska O, Kornilova A, Hyman BT, Perrimon N, Wolfe MS. Gamma-secretase/presenilin inhibitors for Alzheimer's disease phenocopy Notch mutations in Drosophila. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 79-81. PMID 12424225 DOI: 10.1096/fj.02-0394fje  1
2002 Lin X, Perrimon N. Developmental roles of heparan sulfate proteoglycans in Drosophila. Glycoconjugate Journal. 19: 363-8. PMID 12975617 DOI: 10.1023/A:1025329323438  1
2002 Song HJ, Billeter JC, Reynaud E, Carlo T, Spana EP, Perrimon N, Goodwin SF, Baker BS, Taylor BJ. The fruitless gene is required for the proper formation of axonal tracts in the embryonic central nervous system of Drosophila. Genetics. 162: 1703-24. PMID 12524343  1
2002 Hou SX, Zheng Z, Chen X, Perrimon N. The Jak/STAT pathway in model organisms: emerging roles in cell movement. Developmental Cell. 3: 765-78. PMID 12479803 DOI: 10.1016/S1534-5807(02)00376-3  1
2002 Wills Z, Emerson M, Rusch J, Bikoff J, Baum B, Perrimon N, Van Vactor D. A Drosophila homolog of cyclase-associated proteins collaborates with the Abl tyrosine kinase to control midline axon pathfinding. Neuron. 36: 611-22. PMID 12441051 DOI: 10.1016/S0896-6273(02)01022-X  1
2002 Boutros M, Agaisse H, Perrimon N. Sequential activation of signaling pathways during innate immune responses in Drosophila. Developmental Cell. 3: 711-22. PMID 12431377 DOI: 10.1016/S1534-5807(02)00325-8  1
2002 Nybakken K, Perrimon N. Heparan sulfate proteoglycan modulation of developmental signaling in Drosophila. Biochimica Et Biophysica Acta. 1573: 280-91. PMID 12417410  0.52
2002 Hrdlicka L, Gibson M, Kiger A, Micchelli C, Schober M, Schöck F, Perrimon N. Analysis of twenty-four Gal4 lines in Drosophila melanogaster. Genesis (New York, N.Y. : 2000). 34: 51-7. PMID 12324947 DOI: 10.1002/gene.10125  1
2002 Schober M, Perrimon N. Unconventional ways to travel. Nature Cell Biology. 4: E211-2. PMID 12205482 DOI: 10.1038/ncb0902-e211  1
2002 Nybakken K, Perrimon N. Hedgehog signal transduction: recent findings. Current Opinion in Genetics & Development. 12: 503-11. PMID 12200154  0.52
2002 Li WX, Agaisse H, Mathey-Prevot B, Perrimon N. Differential requirement for STAT by gain-of-function and wild-type receptor tyrosine kinase Torso in Drosophila. Development (Cambridge, England). 129: 4241-8. PMID 12183376  1
2002 Schock F, Perrimon N. Molecular mechanisms of epithelial morphogenesis. Annual Review of Cell and Developmental Biology. 18: 463-93. PMID 12142280 DOI: 10.1146/annurev.cellbio.18.022602.131838  1
2002 Schöck F, Perrimon N. Cellular processes associated with germ band retraction in Drosophila. Developmental Biology. 248: 29-39. PMID 12142018 DOI: 10.1006/dbio.2002.0698  1
2002 Moon RT, Bowerman B, Boutros M, Perrimon N. The promise and perils of Wnt signaling through beta-catenin. Science (New York, N.Y.). 296: 1644-6. PMID 12040179 DOI: 10.1126/science.1071549  1
2002 Mathew D, Gramates LS, Packard M, Thomas U, Bilder D, Perrimon N, Gorczyca M, Budnik V. Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein. Current Biology : Cb. 12: 531-9. PMID 11937021 DOI: 10.1016/S0960-9822(02)00758-3  1
2002 Chen HW, Marinissen MJ, Oh SW, Chen X, Melnick M, Perrimon N, Gutkind JS, Hou SX. CKA, a novel multidomain protein, regulates the JUN N-terminal kinase signal transduction pathway in Drosophila. Molecular and Cellular Biology. 22: 1792-803. PMID 11865058 DOI: 10.1128/MCB.22.6.1792-1803.2002  1
2002 Micchelli CA, The I, Selva E, Mogila V, Perrimon N. Rasp, a putative transmembrane acyltransferase, is required for Hedgehog signaling. Development (Cambridge, England). 129: 843-51. PMID 11861468  1
2002 Stronach B, Perrimon N. Activation of the JNK pathway during dorsal closure in Drosophila requires the mixed lineage kinase, slipper. Genes & Development. 16: 377-87. PMID 11825878 DOI: 10.1101/gad.953002  1
2002 Ghiglione C, Bach EA, Paraiso Y, Carraway KL, Noselli S, Perrimon N. Mechanism of activation of the Drosophila EGF Receptor by the TGFalpha ligand Gurken during oogenesis. Development (Cambridge, England). 129: 175-86. PMID 11782411  1
2001 Hong Y, Stronach B, Perrimon N, Jan LY, Jan YN. Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts. Nature. 414: 634-8. PMID 11740559 DOI: 10.1038/414634a  1
2001 Selva EM, Perrimon N. Role of heparan sulfate proteoglycans in cell signaling and cancer. Advances in Cancer Research. 83: 67-80. PMID 11665721  0.4
2001 Baum B, Perrimon N. Spatial control of the actin cytoskeleton in Drosophila epithelial cells. Nature Cell Biology. 3: 883-90. PMID 11584269 DOI: 10.1038/ncb1001-883  0.36
2001 Suzanne M, Perrimon N, Noselli S. The Drosophila JNK pathway controls the morphogenesis of the egg dorsal appendages and micropyle. Developmental Biology. 237: 282-94. PMID 11543614 DOI: 10.1006/dbio.2001.0384  0.44
2001 Selva EM, Hong K, Baeg GH, Beverley SM, Turco SJ, Perrimon N, Häcker U. Dual role of the fringe connection gene in both heparan sulphate and fringe-dependent signalling events. Nature Cell Biology. 3: 809-15. PMID 11533660 DOI: 10.1038/ncb0901-809  1
2001 Stronach BE, Perrimon N. Investigation of leading edge formation at the interface of amnioserosa and dorsal ectoderm in the Drosophila embryo. Development (Cambridge, England). 128: 2905-13. PMID 11532914  1
2001 Vincent S, Perkins LA, Perrimon N. Doublesex surprises. Cell. 106: 399-402. PMID 11525726 DOI: 10.1016/S0092-8674(01)00468-8  1
2001 Vincent S, Perrimon N. Developmental biology. Fishing for morphogens. Nature. 411: 533, 535-6. PMID 11385549 DOI: 10.1038/35079214  0.96
2001 Bai J, Chiu W, Wang J, Tzeng T, Perrimon N, Hsu J. The cell adhesion molecule Echinoid defines a new pathway that antagonizes the Drosophila EGF receptor signaling pathway. Development (Cambridge, England). 128: 591-601. PMID 11171342  0.56
2001 Baeg GH, Lin X, Khare N, Baumgartner S, Perrimon N. Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless. Development (Cambridge, England). 128: 87-94. PMID 11092814  1
2000 Noselli S, Perrimon N. Signal transduction. Are there close encounters between signaling pathways? Science (New York, N.Y.). 290: 68-9. PMID 11183153  0.44
2000 Zeidler MP, Perrimon N, Strutt DI. Multiple roles for four-jointed in planar polarity and limb patterning. Developmental Biology. 228: 181-96. PMID 11112323 DOI: 10.1006/dbio.2000.9940  0.72
2000 Noll E, Medina M, Hartley D, Zhou J, Perrimon N, Kosik KS. Presenilin affects arm/beta-catenin localization and function in Drosophila. Developmental Biology. 227: 450-64. PMID 11071766 DOI: 10.1006/dbio.2000.9925  1
2000 Li W, Noll E, Perrimon N. Identification of autosomal regions involved in Drosophila Raf function. Genetics. 156: 763-74. PMID 11014822  1
2000 Zeidler MP, Perrimon N. Sex determination: co-opted signals determine gender. Current Biology : Cb. 10: R682-4. PMID 10996811  0.72
2000 Baum B, Li W, Perrimon N. A cyclase-associated protein regulates actin and cell polarity during Drosophila oogenesis and in yeast. Current Biology : Cb. 10: 964-73. PMID 10985383  0.4
2000 Baeg GH, Perrimon N. Functional binding of secreted molecules to heparan sulfate proteoglycans in Drosophila. Current Opinion in Cell Biology. 12: 575-80. PMID 10978892  0.64
2000 Lin X, Perrimon N. Role of heparan sulfate proteoglycans in cell-cell signaling in Drosophila. Matrix Biology : Journal of the International Society For Matrix Biology. 19: 303-7. PMID 10963990 DOI: 10.1016/S0945-053X(00)00073-1  1
2000 Bilder D, Li M, Perrimon N. Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science (New York, N.Y.). 289: 113-6. PMID 10884224 DOI: 10.1126/science.289.5476.113  1
2000 Bilder D, Birnbaum D, Borg JP, Bryant P, Huigbretse J, Jansen E, Kennedy MB, Labouesse M, Legouis R, Mechler B, Perrimon N, Petit M, Sinha P. Collective nomenclature for LAP proteins. Nature Cell Biology. 2: E114. PMID 10878817 DOI: 10.1038/35017119  1
2000 Zeidler MP, Bach EA, Perrimon N. The roles of the Drosophila JAK/STAT pathway. Oncogene. 19: 2598-606. PMID 10851058 DOI: 10.1038/sj.onc.1203482  1
2000 The I, Perrimon N. Morphogen diffusion: the case of the wingless protein. Nature Cell Biology. 2: E79-82. PMID 10806491 DOI: 10.1038/35010511  0.48
2000 Boutros M, Perrimon N. Drosophila genome takes flight. Nature Cell Biology. 2: E53-4. PMID 10783247 DOI: 10.1038/35008678  1
2000 Bilder D, Perrimon N. Localization of apical epithelial determinants by the basolateral PDZ protein Scribble. Nature. 403: 676-80. PMID 10688207 DOI: 10.1038/35001108  1
1999 Zeidler MP, Perrimon N, Strutt DI. The four-jointed gene is required in the Drosophila eye for ommatidial polarity specification. Current Biology : Cb. 9: 1363-72. PMID 10607560  0.72
1999 Martín-Blanco E, Roch F, Noll E, Baonza A, Duffy JB, Perrimon N. A temporal switch in DER signaling controls the specification and differentiation of veins and interveins in the Drosophila wing. Development (Cambridge, England). 126: 5739-47. PMID 10572049  1
1999 Stronach BE, Perrimon N. Stress signaling in Drosophila. Oncogene. 18: 6172-82. PMID 10557109 DOI: 10.1038/sj.onc.1203125  1
1999 The I, Bellaiche Y, Perrimon N. Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan. Molecular Cell. 4: 633-9. PMID 10549295  0.56
1999 Spana E, Perrimon N. The latest in signal transduction, 1999. Specificity in Signal Transduction, Keystone, Colorado, USA, 9-14 April 1999. Trends in Genetics : Tig. 15: 301-2. PMID 10475855 DOI: 10.1016/S0168-9525(99)01791-6  1
1999 Mogila VA, Bellaiche Y, Perrimon N. Expression of I-Sce I in Drosophila to induce DNA double-strand breaks. Methods in Molecular Biology (Clifton, N.J.). 113: 439-45. PMID 10443440 DOI: 10.1385/1-59259-675-4:439  0.56
1999 Lin X, Buff EM, Perrimon N, Michelson AM. Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development. Development (Cambridge, England). 126: 3715-23. PMID 10433902  1
1999 Lin X, Perrimon N. Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling. Nature. 400: 281-4. PMID 10421372 DOI: 10.1038/22343  1
1999 Bellaiche Y, Mogila V, Perrimon N. I-SceI endonuclease, a new tool for studying DNA double-strand break repair mechanisms in Drosophila. Genetics. 152: 1037-44. PMID 10388822  0.56
1999 Zeidler MP, Perrimon N, Strutt DI. Polarity determination in the Drosophila eye: a novel role for unpaired and JAK/STAT signaling. Genes & Development. 13: 1342-53. PMID 10346822  0.72
1999 Perrimon N, McMahon AP. Negative feedback mechanisms and their roles during pattern formation. Cell. 97: 13-6. PMID 10199398  1
1999 Ghiglione C, Carraway KL, Amundadottir LT, Boswell RE, Perrimon N, Duffy JB. The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis. Cell. 96: 847-56. PMID 10102272  1
1999 Gayko U, Cleghon V, Copeland T, Morrison DK, Perrimon N. Synergistic activities of multiple phosphotyrosine residues mediate full signaling from the Drosophila Torso receptor tyrosine kinase. Proceedings of the National Academy of Sciences of the United States of America. 96: 523-8. PMID 9892666  0.56
1999 Ghiglione C, Perrimon N, Perkins LA. Quantitative variations in the level of MAPK activity control patterning of the embryonic termini in Drosophila. Developmental Biology. 205: 181-93. PMID 9882506 DOI: 10.1006/dbio.1998.9102  1
1998 Cleghon V, Feldmann P, Ghiglione C, Copeland TD, Perrimon N, Hughes DA, Morrison DK. Opposing actions of CSW and RasGAP modulate the strength of Torso RTK signaling in the Drosophila terminal pathway. Molecular Cell. 2: 719-27. PMID 9885560  0.44
1998 Shulman JM, Perrimon N, Axelrod JD. Frizzled signaling and the developmental control of cell polarity. Trends in Genetics : Tig. 14: 452-8. PMID 9825673 DOI: 10.1016/S0168-9525(98)01584-4  1
1998 Perrimon N, Duffy JB. Developmental biology. Sending all the right signals. Nature. 396: 18-9. PMID 9817197 DOI: 10.1038/23815  1
1998 Li W, Melnick M, Perrimon N. Dual function of Ras in Raf activation. Development (Cambridge, England). 125: 4999-5008. PMID 9811584  0.4
1998 Harrison DA, McCoon PE, Binari R, Gilman M, Perrimon N. Drosophila unpaired encodes a secreted protein that activates the JAK signaling pathway. Genes & Development. 12: 3252-63. PMID 9784499  1
1998 Axelrod JD, Miller JR, Shulman JM, Moon RT, Perrimon N. Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways. Genes & Development. 12: 2610-22. PMID 9716412  1
1998 Bellaiche Y, The I, Perrimon N. Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion. Nature. 394: 85-8. PMID 9665133 DOI: 10.1038/27932  0.56
1998 Perrimon N, Nusse R. Highlights of the 1998 Wnt meeting, Cambridge, MA, January 9-11. Biochimica Et Biophysica Acta. 1377: R45-9. PMID 9659404 DOI: 10.1016/S0304-419X(98)00007-9  1
1998 Duffy JB, Harrison DA, Perrimon N. Identifying loci required for follicular patterning using directed mosaics. Development (Cambridge, England). 125: 2263-71. PMID 9584125  1
1998 Mathey-Prevot B, Perrimon N. Mammalian and Drosophila blood: JAK of all trades? Cell. 92: 697-700. PMID 9529244  0.52
1998 Häcker U, Perrimon N. DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila. Genes & Development. 12: 274-84. PMID 9436986  1
1997 Riesgo-Escovar JR, Hafen E, Hou XS, Goldstein ES, Perrimon N, Glise B, Noselli S, Kockel L, Zeitlinger J, Staszewski LM, Mlodzik M, Bohmann D. Connecting up the pathways in Drosophila development. Trends in Cell Biology. 7: 421-2. PMID 17708993 DOI: 10.1016/S0962-8924(97)88135-4  0.44
1997 Goode S, Perrimon N. Brainiac and fringe are similar pioneer proteins that impart specificity to notch signaling during Drosophila development. Cold Spring Harbor Symposia On Quantitative Biology. 62: 177-84. PMID 9598350  1
1997 Eberl DF, Duyk GM, Perrimon N. A genetic screen for mutations that disrupt an auditory response in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 94: 14837-42. PMID 9405700 DOI: 10.1073/pnas.94.26.14837  1
1997 Li W, Skoulakis EM, Davis RL, Perrimon N. The Drosophila 14-3-3 protein Leonardo enhances Torso signaling through D-Raf in a Ras 1-dependent manner. Development (Cambridge, England). 124: 4163-71. PMID 9374412  0.4
1997 Häcker U, Lin X, Perrimon N. The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis. Development (Cambridge, England). 124: 3565-73. PMID 9342049  1
1997 Goode S, Perrimon N. Inhibition of patterned cell shape change and cell invasion by Discs large during Drosophila oogenesis. Genes & Development. 11: 2532-44. PMID 9334318  1
1997 Engstrom L, Noll E, Perrimon N. Paradigms to study signal transduction pathways in Drosophila. Current Topics in Developmental Biology. 35: 229-61. PMID 9292272  1
1997 Hou XS, Goldstein ES, Perrimon N. Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway to the Decapentaplegic signal transduction pathway in regulating epithelial cell sheet movement. Genes & Development. 11: 1728-37. PMID 9224721  0.32
1997 Eberl DF, Lorenz LJ, Melnick MB, Sood V, Lasko P, Perrimon N. A new enhancer of position-effect variegation in Drosophila melanogaster encodes a putative RNA helicase that binds chromosomes and is regulated by the cell cycle. Genetics. 146: 951-63. PMID 9215899  1
1997 Li W, Perrimon N. Specificity of receptor tyrosine kinase signaling pathways: lessons from Drosophila. Genetic Engineering. 19: 167-82. PMID 9193108  0.4
1997 Perrimon N, Perkins LA. There must be 50 ways to rule the signal: the case of the Drosophila EGF receptor. Cell. 89: 13-6. PMID 9094709  1
1997 Hou XS, Perrimon N. The JAK-STAT pathway in Drosophila. Trends in Genetics : Tig. 13: 105-10. PMID 9066269  0.32
1997 Yu Y, Li W, Su K, Yussa M, Han W, Perrimon N, Pick L. The nuclear hormone receptor Ftz-F1 is a cofactor for the Drosophila homeodomain protein Ftz. Nature. 385: 552-5. PMID 9020364 DOI: 10.1038/385552a0  1
1996 Goode S, Melnick M, Chou TB, Perrimon N. The neurogenic genes egghead and brainiac define a novel signaling pathway essential for epithelial morphogenesis during Drosophila oogenesis. Development (Cambridge, England). 122: 3863-79. PMID 9012507  1
1996 Kadowaki T, Wilder E, Klingensmith J, Zachary K, Perrimon N. The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing. Genes & Development. 10: 3116-28. PMID 8985181  0.64
1996 Perrimon N, Lanjuin A, Arnold C, Noll E. Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third chromosomes identified by P-element-induced mutations. Genetics. 144: 1681-92. PMID 8978055  1
1996 Perkins LA, Johnson MR, Melnick MB, Perrimon N. The nonreceptor protein tyrosine phosphatase corkscrew functions in multiple receptor tyrosine kinase pathways in Drosophila. Developmental Biology. 180: 63-81. PMID 8948575 DOI: 10.1006/dbio.1996.0285  1
1996 Rulifson EJ, Micchelli CA, Axelrod JD, Perrimon N, Blair SS. wingless refines its own expression domain on the Drosophila wing margin. Nature. 384: 72-4. PMID 8900280 DOI: 10.1038/384072a0  1
1996 Klingensmith J, Yang Y, Axelrod JD, Beier DR, Perrimon N, Sussman DJ. Conservation of dishevelled structure and function between flies and mice: isolation and characterization of Dvl2. Mechanisms of Development. 58: 15-26. PMID 8887313 DOI: 10.1016/S0925-4773(96)00549-7  1
1996 Duffy JB, Perrimon N. Recent advances in understanding signal transduction pathways in worms and flies. Current Opinion in Cell Biology. 8: 231-8. PMID 8791421 DOI: 10.1016/S0955-0674(96)80070-6  1
1996 Hou XS, Melnick MB, Perrimon N. Marelle acts downstream of the Drosophila HOP/JAK kinase and encodes a protein similar to the mammalian STATs. Cell. 84: 411-9. PMID 8608595  0.32
1996 Cleghon V, Gayko U, Copeland TD, Perkins LA, Perrimon N, Morrison DK. Drosophila terminal structure development is regulated by the compensatory activities of positive and negative phosphotyrosine signaling sites on the Torso RTK. Genes & Development. 10: 566-77. PMID 8598287  1
1996 Axelrod JD, Matsuno K, Artavanis-Tsakonas S, Perrimon N. Interaction between Wingless and Notch signaling pathways mediated by dishevelled. Science (New York, N.Y.). 271: 1826-32. PMID 8596950  1
1995 Perrimon N, Lu X, Hou XS, Hsu JC, Melnick MB, Chou TB, Perkins LA. Dissection of the Torso signal transduction pathway in Drosophila. Molecular Reproduction and Development. 42: 515-22. PMID 8607984 DOI: 10.1002/mrd.1080420421  1
1995 Manoukian AS, Yoffe KB, Wilder EL, Perrimon N. The porcupine gene is required for wingless autoregulation in Drosophila. Development (Cambridge, England). 121: 4037-44. PMID 8575304  0.64
1995 Harrison DA, Binari R, Nahreini TS, Gilman M, Perrimon N. Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects. The Embo Journal. 14: 2857-65. PMID 7796812  1
1995 Yin JC, Wallach JS, Wilder EL, Klingensmith J, Dang D, Perrimon N, Zhou H, Tully T, Quinn WG. A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist. Molecular and Cellular Biology. 15: 5123-30. PMID 7651429  1
1995 Yoffe KB, Manoukian AS, Wilder EL, Brand AH, Perrimon N. Evidence for engrailed-independent wingless autoregulation in Drosophila. Developmental Biology. 170: 636-50. PMID 7649390 DOI: 10.1006/dbio.1995.1243  1
1995 Sokol SY, Klingensmith J, Perrimon N, Itoh K. Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled. Development (Cambridge, England). 121: 3487. PMID 7588081  0.64
1994 Brand AH, Perrimon N. Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis. Genes & Development. 8: 629-39. PMID 7926754  1
1994 Brand AH, Manoukian AS, Perrimon N. Ectopic expression in Drosophila. Methods in Cell Biology. 44: 635-54. PMID 7707973  1
1993 Harrison DA, Perrimon N. Simple and efficient generation of marked clones in Drosophila. Current Biology : Cb. 3: 424-33. PMID 15335709 DOI: 10.1016/0960-9822(93)90349-S  1
1993 Brand AH, Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development (Cambridge, England). 118: 401-15. PMID 8223268  1
1992 Eberl DF, Perkins LA, Engelstein M, Hilliker AJ, Perrimon N. Genetic and developmental analysis of polytene section 17 of the X chromosome of Drosophila melanogaster. Genetics. 130: 569-83. PMID 1551578  1
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