F Michael Hoffmann - Publications

Affiliations: 
McArdle Laboratory for Cancer Research University of Wisconsin, Madison, Madison, WI 
Area:
TGF
Website:
http://www.mcardle.wisc.edu/faculty/bio/hoffmann_f.html

74 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Goel SA, Guo LW, Wang B, Guo S, Roenneburg D, Ananiev GE, Hoffmann FM, Kent KC. High-throughput screening identifies idarubicin as a preferential inhibitor of smooth muscle versus endothelial cell proliferation. Plos One. 9: e89349. PMID 24586708 DOI: 10.1371/journal.pone.0089349  1
2013 Goodman CA, McNally RM, Hoffmann FM, Hornberger TA. Smad3 induces atrogin-1, inhibits mTOR and protein synthesis, and promotes muscle atrophy in vivo. Molecular Endocrinology (Baltimore, Md.). 27: 1946-57. PMID 24002653 DOI: 10.1210/me.2013-1194  1
2013 Zeng H, Wu J, Bedford MT, Sbardella G, Hoffmann FM, Bi K, Xu W. A TR-FRET-based functional assay for screening activators of CARM1. Chembiochem : a European Journal of Chemical Biology. 14: 827-35. PMID 23585185 DOI: 10.1002/cbic.201300029  1
2012 Tomasini-Johansson BR, Johnson IA, Hoffmann FM, Mosher DF. Quantitative microtiter fibronectin fibrillogenesis assay: use in high throughput screening for identification of inhibitor compounds. Matrix Biology : Journal of the International Society For Matrix Biology. 31: 360-7. PMID 22986508 DOI: 10.1016/j.matbio.2012.07.003  1
2011 Schiro MM, Stauber SE, Peterson TL, Krueger C, Darnell SJ, Satyshur KA, Drinkwater NR, Newton MA, Hoffmann FM. Mutations in protein-binding hot-spots on the hub protein Smad3 differentially affect its protein interactions and Smad3-regulated gene expression. Plos One. 6: e25021. PMID 21949838 DOI: 10.1371/journal.pone.0025021  1
2010 Krueger C, Hoffmann FM. Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1. Plos One. 5: e15511. PMID 21152098 DOI: 10.1371/journal.pone.0015511  1
2010 Powell E, Huang SX, Xu Y, Rajski SR, Wang Y, Peters N, Guo S, Xu HE, Hoffmann FM, Shen B, Xu W. Identification and characterization of a novel estrogenic ligand actinopolymorphol A. Biochemical Pharmacology. 80: 1221-9. PMID 20599778 DOI: 10.1016/j.bcp.2010.06.030  1
2010 Mehraein-Ghomi F, Basu HS, Church DR, Hoffmann FM, Wilding G. Androgen receptor requires JunD as a coactivator to switch on an oxidative stress generation pathway in prostate cancer cells. Cancer Research. 70: 4560-8. PMID 20460526 DOI: 10.1158/0008-5472.CAN-09-3596  1
2010 Luo Y, Li W, Ju J, Yuan Q, Peters NR, Hoffmann FM, Huang SX, Bugni TS, Rajski S, Osada H, Shen B. Functional characterization of TtnD and TtnF, unveiling new insights into tautomycetin biosynthesis. Journal of the American Chemical Society. 132: 6663-71. PMID 20426415 DOI: 10.1021/ja9082446  1
2009 Das S, Becker BN, Hoffmann FM, Mertz JE. Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway. Bmc Cell Biology. 10: 94. PMID 20025777 DOI: 10.1186/1471-2121-10-94  1
2009 Ewald JA, Peters N, Desotelle JA, Hoffmann FM, Jarrard DF. A high-throughput method to identify novel senescence-inducing compounds. Journal of Biomolecular Screening. 14: 853-8. PMID 19641224 DOI: 10.1177/1087057109340314  1
2009 Ju J, Li W, Yuan Q, Peters NR, Hoffmann FM, Rajski SR, Osada H, Shen B. Functional characterization of ttmM unveils new tautomycin analogs and insight into tautomycin biosynthesis and activity. Organic Letters. 11: 1639-42. PMID 19281218 DOI: 10.1021/ol900293j  1
2009 Ju J, Rajski SR, Lim SK, Seo JW, Peters NR, Hoffmann FM, Shen B. Lactimidomycin, iso-migrastatin and related glutarimide-containing 12-membered macrolides are extremely potent inhibitors of cell migration. Journal of the American Chemical Society. 131: 1370-1. PMID 19132897 DOI: 10.1021/ja808462p  1
2008 Ju J, Rajski SR, Lim SK, Seo JW, Peters NR, Hoffmann FM, Shen B. Evaluation of new migrastatin and dorrigocin congeners unveils cell migration inhibitors with dramatically improved potency. Bioorganic & Medicinal Chemistry Letters. 18: 5951-4. PMID 18684620 DOI: 10.1016/j.bmcl.2008.07.072  1
2007 Yang B, O'Herrin SM, Wu J, Reagan-Shaw S, Ma Y, Bhat KM, Gravekamp C, Setaluri V, Peters N, Hoffmann FM, Peng H, Ivanov AV, Simpson AJ, Longley BJ. MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines. Cancer Research. 67: 9954-62. PMID 17942928 DOI: 10.1158/0008-5472.CAN-07-1478  1
2006 Lim SK, Hoffmann FM. Smad4 cooperates with lymphoid enhancer-binding factor 1/T cell-specific factor to increase c-myc expression in the absence of TGF-beta signaling. Proceedings of the National Academy of Sciences of the United States of America. 103: 18580-5. PMID 17132729 DOI: 10.1073/pnas.0604773103  1
2006 Ahmed A, Peters NR, Fitzgerald MK, Watson JA, Hoffmann FM, Thorson JS. Colchicine glycorandomization influences cytotoxicity and mechanism of action. Journal of the American Chemical Society. 128: 14224-5. PMID 17076473 DOI: 10.1021/ja064686s  1
2006 Zhao BM, Hoffmann FM. Inhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA. Molecular Biology of the Cell. 17: 3819-31. PMID 16775010 DOI: 10.1091/mbc.E05-10-0990  1
2005 Langenhan JM, Peters NR, Guzei IA, Hoffmann FM, Thorson JS. Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization. Proceedings of the National Academy of Sciences of the United States of America. 102: 12305-10. PMID 16105948 DOI: 10.1073/pnas.0503270102  1
2005 Martin M, Ahern-Djamali SM, Hoffmann FM, Saxton WM. Abl tyrosine kinase and its substrate Ena/VASP have functional interactions with kinesin-1. Molecular Biology of the Cell. 16: 4225-30. PMID 15975902 DOI: 10.1091/mbc.E05-02-0116  1
2005 Cui Q, Lim SK, Zhao B, Hoffmann FM. Selective inhibition of TGF-beta responsive genes by Smad-interacting peptide aptamers from FoxH1, Lef1 and CBP. Oncogene. 24: 3864-74. PMID 15750622 DOI: 10.1038/sj.onc.1208556  1
1999 Juang JL, Hoffmann FM. Drosophila abelson interacting protein (dAbi) is a positive regulator of abelson tyrosine kinase activity. Oncogene. 18: 5138-47. PMID 10498863 DOI: 10.1038/sj.onc.1202911  1
1999 Johnson K, Kirkpatrick H, Comer A, Hoffmann FM, Laughon A. Interaction of Smad complexes with tripartite DNA-binding sites. The Journal of Biological Chemistry. 274: 20709-16. PMID 10400705 DOI: 10.1074/jbc.274.29.20709  1
1999 Ahern-Djamali SM, Bachmann C, Hua P, Reddy SK, Kastenmeier AS, Walter U, Hoffmann FM. Identification of profilin and src homology 3 domains as binding partners for Drosophila enabled. Proceedings of the National Academy of Sciences of the United States of America. 96: 4977-82. PMID 10220404 DOI: 10.1073/pnas.96.9.4977  1
1999 Fogerty FJ, Juang JL, Petersen J, Clark MJ, Hoffmann FM, Mosher DF. Dominant effects of the bcr-abl oncogene on Drosophila morphogenesis. Oncogene. 18: 219-32. PMID 9926937 DOI: 10.1038/sj.onc.1202239  1
1998 Ahern-Djamali SM, Comer AR, Bachmann C, Kastenmeier AS, Reddy SK, Beckerle MC, Walter U, Hoffmann FM. Mutations in Drosophila enabled and rescue by human vasodilator-stimulated phosphoprotein (VASP) indicate important functional roles for Ena/VASP homology domain 1 (EVH1) and EVH2 domains. Molecular Biology of the Cell. 9: 2157-71. PMID 9693373  1
1998 Chen Y, Riese MJ, Killinger MA, Hoffmann FM. A genetic screen for modifiers of Drosophila decapentaplegic signaling identifies mutations in punt, Mothers against dpp and the BMP-7 homologue, 60A. Development (Cambridge, England). 125: 1759-68. PMID 9521913  1
1998 Comer AR, Ahern-Djamali SM, Juang JL, Jackson PD, Hoffmann FM. Phosphorylation of Enabled by the Drosophila Abelson tyrosine kinase regulates the in vivo function and protein-protein interactions of Enabled. Molecular and Cellular Biology. 18: 152-60. PMID 9418863  1
1997 Singer MA, Penton A, Twombly V, Hoffmann FM, Gelbart WM. Signaling through both type I DPP receptors is required for anterior-posterior patterning of the entire Drosophila wing. Development (Cambridge, England). 124: 79-89. PMID 9006069  1
1997 Penton A, Selleck SB, Hoffmann FM. Regulation of cell cycle synchronization by decapentaplegic during Drosophila eye development. Science (New York, N.Y.). 275: 203-6. PMID 8985012 DOI: 10.1126/science.275.5297.203  1
1996 Penton A, Hoffmann FM. Decapentaplegic restricts the domain of wingless during Drosophila limb patterning. Nature. 382: 162-4. PMID 8700205 DOI: 10.1038/382162a0  1
1996 Morimura S, Maves L, Chen Y, Hoffmann FM. decapentaplegic overexpression affects Drosophila wing and leg imaginal disc development and wingless expression. Developmental Biology. 177: 136-51. PMID 8660883 DOI: 10.1006/dbio.1996.0151  1
1995 Hill KK, Bedian V, Juang JL, Hoffmann FM. Genetic interactions between the Drosophila Abelson (Abl) tyrosine kinase and failed axon connections (fax), a novel protein in axon bundles. Genetics. 141: 595-606. PMID 8647396  1
1995 Comer AR, Liebl EC, Hoffmann FM. Can clues to the molecular defects in chronic myelogenous leukemia come from genetic studies on the Abelson tyrosine kinase in fruit flies? The Journal of Laboratory and Clinical Medicine. 125: 686-91. PMID 7769362  1
1995 Letsou A, Arora K, Wrana JL, Simin K, Twombly V, Jamal J, Staehling-Hampton K, Hoffmann FM, Gelbart WM, Massagué J. Drosophila Dpp signaling is mediated by the punt gene product: a dual ligand-binding type II receptor of the TGF beta receptor family. Cell. 80: 899-908. PMID 7697720 DOI: 10.1016/0092-8674(95)90293-7  1
1995 Holley SA, Jackson PD, Sasai Y, Lu B, De Robertis EM, Hoffmann FM, Ferguson EL. A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin. Nature. 376: 249-53. PMID 7617035 DOI: 10.1038/376249a0  1
1995 Staehling-Hampton K, Laughon AS, Hoffmann FM. A Drosophila protein related to the human zinc finger transcription factor PRDII/MBPI/HIV-EP1 is required for dpp signaling. Development (Cambridge, England). 121: 3393-403. PMID 7588072  1
1995 Gertler FB, Comer AR, Juang JL, Ahern SM, Clark MJ, Liebl EC, Hoffmann FM. enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties. Genes & Development. 9: 521-33. PMID 7535279  1
1995 Holley SA, Jackson PD, Sasal Y, Lu B, De Robertis EM, Hoffmann FM, Ferguson EL. A conserved system for dorsal - ventral patterning in insects and vertebrates involving sog and chordin Nature. 376: XII-253.  1
1994 Jackson PD, Hoffmann FM. Embryonic expression patterns of the Drosophila decapentaplegic gene: separate regulatory elements control blastoderm expression and lateral ectodermal expression. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 199: 28-44. PMID 8167377 DOI: 10.1002/aja.1001990104  1
1994 Staehling-Hampton K, Jackson PD, Clark MJ, Brand AH, Hoffmann FM. Specificity of bone morphogenetic protein-related factors: cell fate and gene expression changes in Drosophila embryos induced by decapentaplegic but not 60A. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 5: 585-93. PMID 8086336  1
1994 Penton A, Chen Y, Staehling-Hampton K, Wrana JL, Attisano L, Szidonya J, Cassill JA, Massagué J, Hoffmann FM. Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor. Cell. 78: 239-50. PMID 8044838 DOI: 10.1016/0092-8674(94)90294-1  1
1994 Staehling-Hampton K, Hoffmann FM, Baylies MK, Rushton E, Bate M. dpp induces mesodermal gene expression in Drosophila. Nature. 372: 783-6. PMID 7997266  1
1994 Staehling-Hampton K, Hoffmann FM. Ectopic decapentaplegic in the Drosophila midgut alters the expression of five homeotic genes, dpp, and wingless, causing specific morphological defects. Developmental Biology. 164: 502-12. PMID 7913899 DOI: 10.1006/dbio.1994.1219  1
1993 Masucci JD, Hoffmann FM. Identification of two regions from the Drosophila decapentaplegic gene required for embryonic midgut development and larval viability. Developmental Biology. 159: 276-87. PMID 8365566 DOI: 10.1006/dbio.1993.1240  1
1993 Sampath TK, Rashka KE, Doctor JS, Tucker RF, Hoffmann FM. Drosophila transforming growth factor beta superfamily proteins induce endochondral bone formation in mammals. Proceedings of the National Academy of Sciences of the United States of America. 90: 6004-8. PMID 8327474  1
1993 Gertler FB, Hill KK, Clark MJ, Hoffmann FM. Dosage-sensitive modifiers of Drosophila abl tyrosine kinase function: prospero, a regulator of axonal outgrowth, and disabled, a novel tyrosine kinase substrate. Genes & Development. 7: 441-53. PMID 7680635  0.76
1992 Hoffmann FM, Sternberg PW, Herskowitz I. Learning about cancer genes through invertebrate genetics. Current Opinion in Genetics & Development. 2: 45-52. PMID 1633426 DOI: 10.1016/S0959-437X(05)80320-X  1
1992 Doctor JS, Jackson PD, Rashka KE, Visalli M, Hoffmann FM. Sequence, biochemical characterization, and developmental expression of a new member of the TGF-beta superfamily in Drosophila melanogaster. Developmental Biology. 151: 491-505. PMID 1601181  0.56
1992 Hoffmann FM. TGF-beta family factors in Drosophila morphogenesis. Molecular Reproduction and Development. 32: 173-8. PMID 1353353 DOI: 10.1002/mrd.1080320214  1
1992 Bennett RL, Hoffmann FM. Increased levels of the Drosophila Abelson tyrosine kinase in nerves and muscles: subcellular localization and mutant phenotypes imply a role in cell-cell interactions. Development (Cambridge, England). 116: 953-66. PMID 1295746  1
1991 Doctor JS, Hoffmann FM, Olwin BB. Identification of a fibroblast growth factor-binding protein in Drosophila melanogaster. Molecular and Cellular Biology. 11: 2319-23. PMID 1848676  1
1991 Hoffmann FM. Drosophila abl and genetic redundancy in signal transduction. Trends in Genetics : Tig. 7: 351-5. PMID 1820686 DOI: 10.1016/0168-9525(91)90254-F  1
1991 Hoffmann FM. Transforming growth factor-beta-related genes in Drosophila and vertebrate development. Current Opinion in Cell Biology. 3: 947-52. PMID 1687650  1
1990 Elkins T, Zinn K, McAllister L, Hoffmann FM, Goodman CS. Genetic analysis of a Drosophila neural cell adhesion molecule: interaction of fasciclin I and Abelson tyrosine kinase mutations. Cell. 60: 565-75. PMID 2406026 DOI: 10.1016/0092-8674(90)90660-7  1
1990 Gertler FB, Doctor JS, Hoffmann FM. Genetic suppression of mutations in the Drosophila abl proto-oncogene homolog. Science (New York, N.Y.). 248: 857-60. PMID 2188361  1
1990 Masucci JD, Miltenberger RJ, Hoffmann FM. Pattern-specific expression of the Drosophila decapentaplegic gene in imaginal disks is regulated by 3' cis-regulatory elements. Genes & Development. 4: 2011-23. PMID 2177439  1
1990 Henkemeyer M, West SR, Gertler FB, Hoffmann FM. A novel tyrosine kinase-independent function of Drosophila abl correlates with proper subcellular localization. Cell. 63: 949-60. PMID 2175256 DOI: 10.1016/0092-8674(90)90498-4  1
1990 Holland GD, Henkemeyer MJ, Kaehler DA, Hoffmann FM, Risser R. Conservation of function of Drosophila melanogaster abl and murine v-abl proteins in transformation of mammalian cells. Journal of Virology. 64: 2226-35. PMID 2157882  1
1990 St Johnston RD, Hoffmann FM, Blackman RK, Segal D, Grimaila R, Padgett RW, Irick HA, Gelbart WM. Molecular organization of the decapentaplegic gene in Drosophila melanogaster. Genes & Development. 4: 1114-27. PMID 2120113  1
1990 Belote JM, Hoffmann FM, McKeown M, Chorsky RL, Baker BS. Cytogenetic analysis of chromosome region 73AD of Drosophila melanogaster. Genetics. 125: 783-93. PMID 2118870  1
1990 Panganiban GE, Reuter R, Scott MP, Hoffmann FM. A Drosophila growth factor homolog, decapentaplegic, regulates homeotic gene expression within and across germ layers during midgut morphogenesis. Development (Cambridge, England). 110: 1041-50. PMID 1983114  1
1990 Reuter R, Panganiban GE, Hoffmann FM, Scott MP. Homeotic genes regulate the spatial expression of putative growth factors in the visceral mesoderm of Drosophila embryos. Development (Cambridge, England). 110: 1031-40. PMID 1983113  1
1990 Panganiban GE, Rashka KE, Neitzel MD, Hoffmann FM. Biochemical characterization of the Drosophila dpp protein, a member of the transforming growth factor beta family of growth factors. Molecular and Cellular Biology. 10: 2669-77. PMID 1692958  1
1990 Muskavitch MAT, Hoffmann FM. 10 Homologs of Vertebrate Growth Factors in Drosophila melanogaster and Other Invertebrates Current Topics in Developmental Biology. 24: 289-328. DOI: 10.1016/S0070-2153(08)60091-5  1
1989 Hoffmann FM. Roles of Drosophila proto-oncogene and growth factor homologs during development of the fly. Current Topics in Microbiology and Immunology. 147: 1-29. PMID 2515942  1
1989 Gertler FB, Bennett RL, Clark MJ, Hoffmann FM. Drosophila abl tyrosine kinase in embryonic CNS axons: a role in axonogenesis is revealed through dosage-sensitive interactions with disabled. Cell. 58: 103-13. PMID 2502313 DOI: 10.1016/0092-8674(89)90407-8  1
1988 Henkemeyer MJ, Bennett RL, Gertler FB, Hoffmann FM. DNA sequence, structure, and tyrosine kinase activity of the Drosophila melanogaster Abelson proto-oncogene homolog. Molecular and Cellular Biology. 8: 843-53. PMID 2832740  1
1987 Henkemeyer MJ, Gertler FB, Goodman W, Hoffmann FM. The Drosophila Abelson proto-oncogene homolog: identification of mutant alleles that have pleiotropic effects late in development. Cell. 51: 821-8. PMID 3119227 DOI: 10.1016/0092-8674(87)90105-X  1
1987 Hoffmann FM, Goodman W. Identification in transgenic animals of the Drosophila decapentaplegic sequences required for embryonic dorsal pattern formation. Genes & Development. 1: 615-25. PMID 2824286  1
1985 Gelbart WM, Irish VF, St Johnston RD, Hoffmann FM, Blackman RK, Segal D, Posakony LM, Grimaila R. The decapentaplegic gene complex in Drosophila melanogaster. Cold Spring Harbor Symposia On Quantitative Biology. 50: 119-25. PMID 3938359  1
1983 Hoffmann FM, Fresco LD, Hoffman-Falk H, Shilo BZ. Nucleotide sequences of the Drosophila src and abl homologs: conservation and variability in the src family oncogenes. Cell. 35: 393-401. PMID 6317185 DOI: 10.1016/0092-8674(83)90172-1  1
1983 Hoffman-Falk H, Einat P, Shilo BZ, Hoffmann FM. Drosophila melanogaster DNA clones homologous to vertebrate oncogenes: evidence for a common ancestor to the src and abl cellular genes. Cell. 32: 589-98. PMID 6297802 DOI: 10.1016/0092-8674(83)90478-6  1
1982 Spencer FA, Hoffmann FM, Gelbart WM. Decapentaplegic: a gene complex affecting morphogenesis in Drosophila melanogaster. Cell. 28: 451-61. PMID 6804094 DOI: 10.1016/0092-8674(82)90199-4  1
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