Philip W. Ingham, BA DPhil - Publications

Affiliations: 
2013- Lee Kong Chian School of Medicine Nanyang Technological University Singapore 
Area:
Hedgehog signalling

169 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Stainier DYR, Raz E, Lawson ND, Ekker SC, Burdine RD, Eisen JS, Ingham PW, Schulte-Merker S, Yelon D, Weinstein BM, Mullins MC, Wilson SW, Ramakrishnan L, Amacher SL, Neuhauss SCF, et al. Guidelines for morpholino use in zebrafish. Plos Genetics. 13: e1007000. PMID 29049395 DOI: 10.1371/journal.pgen.1007000  0.32
2016 Zhao Z, Lee RT, Pusapati GV, Iyu A, Rohatgi R, Ingham PW. An essential role for Grk2 in Hedgehog signalling downstream of Smoothened. Embo Reports. PMID 27113758 DOI: 10.15252/embr.201541532  1
2016 Robertson AL, Ogryzko NV, Henry KM, Loynes CA, Foulkes MJ, Meloni MM, Wang X, Ford C, Jackson M, Ingham PW, Wilson HL, Farrow SN, Solari R, Flower RJ, Jones S, et al. Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen. Disease Models & Mechanisms. PMID 27079522 DOI: 10.1242/dmm.024935  1
2016 Leow SC, Poschmann J, Too PG, Yin J, Joseph R, McFarlane C, Dogra S, Shabbir A, Ingham PW, Prabhakar S, Leow MK, Lee YS, Ng KL, Chong YS, Gluckman PD, et al. The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis. Development (Cambridge, England). PMID 26893351 DOI: 10.1242/dev.131573  1
2016 Lee RT, Zhao Z, Ingham PW. Hedgehog signalling. Development (Cambridge, England). 143: 367-72. PMID 26839340 DOI: 10.1242/dev.120154  1
2016 Ingham PW. Drosophila Segment Polarity Mutants and the Rediscovery of the Hedgehog Pathway Genes Current Topics in Developmental Biology. DOI: 10.1016/bs.ctdb.2016.01.007  1
2015 Vaz C, Wee CW, Lee GP, Ingham PW, Tanavde V, Mathavan S. Deep sequencing of small RNA facilitates tissue and sex associated microRNA discovery in zebrafish. Bmc Genomics. 16: 950. PMID 26574018 DOI: 10.1186/s12864-015-2135-7  1
2015 Ono Y, Yu W, Jackson HE, Parkin CA, Ingham PW. Adaxial cell migration in the zebrafish embryo is an active cell autonomous property that requires the Prdm1a transcription factor. Differentiation; Research in Biological Diversity. 89: 77-86. PMID 25861970 DOI: 10.1016/j.diff.2015.03.002  1
2015 Jackson HE, Ono Y, Wang X, Elworthy S, Cunliffe VT, Ingham PW. The role of Sox6 in zebrafish muscle fiber type specification. Skeletal Muscle. 5: 2. PMID 25671076 DOI: 10.1186/s13395-014-0026-2  1
2014 Venkatesh B, Lee AP, Ravi V, Maurya AK, Korzh V, Lim ZW, Ingham PW, Boehm T, Brenner S, Warren WC. On the origin of SCPP genes. Evolution & Development. 16: 125-6. PMID 24798313 DOI: 10.1111/ede.12072  1
2014 van Impel A, Zhao Z, Hermkens DM, Roukens MG, Fischer JC, Peterson-Maduro J, Duckers H, Ober EA, Ingham PW, Schulte-Merker S. Divergence of zebrafish and mouse lymphatic cell fate specification pathways. Development (Cambridge, England). 141: 1228-38. PMID 24523456 DOI: 10.1242/dev.105031  1
2014 Burgon J, Robertson AL, Sadiku P, Wang X, Hooper-Greenhill E, Prince LR, Walker P, Hoggett EE, Ward JR, Farrow SN, Zuercher WJ, Jeffrey P, Savage CO, Ingham PW, Hurlstone AF, et al. Serum and glucocorticoid-regulated kinase 1 regulates neutrophil clearance during inflammation resolution. Journal of Immunology (Baltimore, Md. : 1950). 192: 1796-805. PMID 24431232 DOI: 10.4049/jimmunol.1300087  1
2014 Venkatesh B, Lee AP, Ravi V, Maurya AK, Lian MM, Swann JB, Ohta Y, Flajnik MF, Sutoh Y, Kasahara M, Hoon S, Gangu V, Roy SW, Irimia M, Korzh V, ... ... Ingham PW, et al. Elephant shark genome provides unique insights into gnathostome evolution. Nature. 505: 174-9. PMID 24402279 DOI: 10.1038/nature12826  1
2014 Wang X, Robertson AL, Li J, Chai RJ, Haishan W, Sadiku P, Ogryzko NV, Everett M, Yoganathan K, Luo HR, Renshaw SA, Ingham PW. Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library. Disease Models & Mechanisms. 7: 163-9. PMID 24291762 DOI: 10.1242/dmm.012047  1
2014 Venkatesh B, Lee AP, Ravi V, Maurya AK, Lian MM, Swann JB, Ohta Y, Flajnik MF, Sutoh Y, Kasahara M, Hoon S, Gangu V, Roy SW, Irimia M, Korzh V, ... ... Ingham PW, et al. Corrigendum: Elephant shark genome provides unique insights into gnathostome evolution Nature. 513: 574. DOI: 10.1038/nature13699  1
2013 Wilkinson RN, Elworthy S, Ingham PW, van Eeden FJ. A method for high-throughput PCR-based genotyping of larval zebrafish tail biopsies. Biotechniques. 55: 314-6. PMID 24344681 DOI: 10.2144/000114116  1
2013 Maurya AK, Ben J, Zhao Z, Lee RT, Niah W, Ng AS, Iyu A, Yu W, Elworthy S, van Eeden FJ, Ingham PW. Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo. Plos Genetics. 9: e1003955. PMID 24339784 DOI: 10.1371/journal.pgen.1003955  1
2013 Nachtergaele S, Whalen DM, Mydock LK, Zhao Z, Malinauskas T, Krishnan K, Ingham PW, Covey DF, Siebold C, Rohatgi R. Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling. Elife. 2: e01340. PMID 24171105 DOI: 10.7554/eLife.01340  1
2013 Flinn LJ, Keatinge M, Bretaud S, Mortiboys H, Matsui H, De Felice E, Woodroof HI, Brown L, McTighe A, Soellner R, Allen CE, Heath PR, Milo M, Muqit MM, Reichert AS, ... ... Ingham PW, et al. TigarB causes mitochondrial dysfunction and neuronal loss in PINK1 deficiency. Annals of Neurology. 74: 837-47. PMID 24027110 DOI: 10.1002/ana.23999  1
2013 Jackson HE, Ingham PW. Control of muscle fibre-type diversity during embryonic development: the zebrafish paradigm. Mechanisms of Development. 130: 447-57. PMID 23811405 DOI: 10.1016/j.mod.2013.06.001  1
2013 Hynes NE, Ingham PW, Lim WA, Marshall CJ, Massagué J, Pawson T. Signalling change: signal transduction through the decades. Nature Reviews. Molecular Cell Biology. 14: 393-8. PMID 23636498 DOI: 10.1038/nrm3581  1
2013 Carney TJ, Ingham PW. Drugging Hedgehog: signaling the pathway to translation. Bmc Biology. 11: 37. PMID 23587183 DOI: 10.1186/1741-7007-11-37  1
2013 Hewamadduma CA, Grierson AJ, Ma TP, Pan L, Moens CB, Ingham PW, Ramesh T, Shaw PJ. Tardbpl splicing rescues motor neuron and axonal development in a mutant tardbp zebrafish. Human Molecular Genetics. 22: 2376-86. PMID 23427147 DOI: 10.1093/hmg/ddt082  1
2012 Ingham PW. Zebrafish genetics gets the Scube on Hedgehog secretion. Genes & Development. 26: 2468-70. PMID 23154980 DOI: 10.1101/gad.207126.112  1
2012 Baxendale S, Holdsworth CJ, Meza Santoscoy PL, Harrison MR, Fox J, Parkin CA, Ingham PW, Cunliffe VT. Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures. Disease Models & Mechanisms. 5: 773-84. PMID 22730455 DOI: 10.1242/dmm.010090  1
2012 Wilkinson RN, Koudijs MJ, Patient RK, Ingham PW, Schulte-Merker S, van Eeden FJ. Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish. Blood. 120: 477-88. PMID 22668851 DOI: 10.1182/blood-2011-10-383729  1
2012 Ingham PW. Hedgehog signaling. Cold Spring Harbor Perspectives in Biology. 4. PMID 22661636 DOI: 10.1101/cshperspect.a011221  1
2011 Ben J, Elworthy S, Ng AS, van Eeden F, Ingham PW. Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates. Development (Cambridge, England). 138: 4969-78. PMID 22028029 DOI: 10.1242/dev.070862  1
2011 Seger C, Hargrave M, Wang X, Chai RJ, Elworthy S, Ingham PW. Analysis of Pax7 expressing myogenic cells in zebrafish muscle development, injury, and models of disease. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 2440-51. PMID 21954137 DOI: 10.1002/dvdy.22745  1
2011 Korzh S, Winata CL, Zheng W, Yang S, Yin A, Ingham P, Korzh V, Gong Z. The interaction of epithelial Ihha and mesenchymal Fgf10 in zebrafish esophageal and swimbladder development Developmental Biology. 359: 262-276. PMID 21925490 DOI: 10.1016/j.ydbio.2011.08.024  1
2011 Wang X, Ono Y, Tan SC, Chai RJ, Parkin C, Ingham PW. Prdm1a and miR-499 act sequentially to restrict Sox6 activity to the fast-twitch muscle lineage in the zebrafish embryo. Development (Cambridge, England). 138: 4399-404. PMID 21880783 DOI: 10.1242/dev.070516  1
2011 Bretaud S, MacRaild S, Ingham PW, Bandmann O. The influence of the zebrafish genetic background on Parkinson's disease-related aspects. Zebrafish. 8: 103-8. PMID 21745139 DOI: 10.1089/zeb.2011.0697  1
2011 Elks PM, van Eeden FJ, Dixon G, Wang X, Reyes-Aldasoro CC, Ingham PW, Whyte MK, Walmsley SR, Renshaw SA. Activation of hypoxia-inducible factor-1α (Hif-1α) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model. Blood. 118: 712-22. PMID 21555741 DOI: 10.1182/blood-2010-12-324186  1
2011 Ingham PW, Nakano Y, Seger C. Mechanisms and functions of Hedgehog signalling across the metazoa. Nature Reviews. Genetics. 12: 393-406. PMID 21502959 DOI: 10.1038/nrg2984  1
2011 Maurya AK, Tan H, Souren M, Wang X, Wittbrodt J, Ingham PW. Integration of Hedgehog and BMP signalling by the engrailed2a gene in the zebrafish myotome. Development (Cambridge, England). 138: 755-65. PMID 21266411 DOI: 10.1242/dev.062521  1
2011 Ingham PW. Evolutionary Divergence in the Hedgehog Pathway Developmental Cell. 21: e2. DOI: 10.1016/j.devcel.2011.06.032  1
2010 Renshaw SA, Ingham PW. Zebrafish models of the immune response: taking it on the ChIn. Bmc Biology. 8: 148. PMID 21176245 DOI: 10.1186/1741-7007-8-148  1
2010 Kim HR, Richardson J, van Eeden F, Ingham PW. Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish. Bmc Biology. 8: 65. PMID 20487519 DOI: 10.1186/1741-7007-8-65  1
2010 Carney TJ, Feitosa NM, Sonntag C, Slanchev K, Kluger J, Kiyozumi D, Gebauer JM, Coffin Talbot J, Kimmel CB, Sekiguchi K, Wagener R, Schwarz H, Ingham PW, Hammerschmidt M. Genetic analysis of fin development in zebrafish identifies furin and hemicentin1 as potential novel fraser syndrome disease genes. Plos Genetics. 6: e1000907. PMID 20419147 DOI: 10.1371/journal.pgen.1000907  1
2010 Loynes CA, Martin JS, Robertson A, Trushell DM, Ingham PW, Whyte MK, Renshaw SA. Pivotal Advance: Pharmacological manipulation of inflammation resolution during spontaneously resolving tissue neutrophilia in the zebrafish. Journal of Leukocyte Biology. 87: 203-12. PMID 19850882 DOI: 10.1189/jlb.0409255  1
2009 Ingham PW, McMahon AP. Hedgehog signalling: Kif7 is not that fishy after all. Current Biology : Cb. 19: R729-31. PMID 19906571 DOI: 10.1016/j.cub.2009.07.060  1
2009 Lee SLC, Rouhi P, Jensen LD, Zhang D, Ji H, Hauptmann G, Ingham P, Cao Y. Hypoxia-induced pathological angiogenesis mediates tumor cell dissemination, invasion, and metastasis in a zebrafish tumor model Proceedings of the National Academy of Sciences of the United States of America. 106: 19485-19490. PMID 19887629 DOI: 10.1073/pnas.0909228106  1
2009 Packham IM, Gray C, Heath PR, Hellewell PG, Ingham PW, Crossman DC, Milo M, Chico TJ. Microarray profiling reveals CXCR4a is downregulated by blood flow in vivo and mediates collateral formation in zebrafish embryos. Physiological Genomics. 38: 319-27. PMID 19509081 DOI: 10.1152/physiolgenomics.00049.2009  1
2009 Flinn L, Mortiboys H, Volkmann K, Köster RW, Ingham PW, Bandmann O. Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio). Brain : a Journal of Neurology. 132: 1613-23. PMID 19439422 DOI: 10.1093/brain/awp108  1
2009 Ingham PW. The power of the zebrafish for disease analysis. Human Molecular Genetics. 18: R107-12. PMID 19297397 DOI: 10.1093/hmg/ddp091  1
2009 Hammond KL, Baxendale S, McCauley DW, Ingham PW, Whitfield TT. Expression of patched, prdm1 and engrailed in the lamprey somite reveals conserved responses to Hedgehog signaling. Evolution & Development. 11: 27-40. PMID 19196331 DOI: 10.1111/j.1525-142X.2008.00300.x  1
2009 Parkin CA, Allen CE, Ingham PW. Hedgehog signalling is required for cloacal development in the zebrafish embryo. The International Journal of Developmental Biology. 53: 45-57. PMID 19123126 DOI: 10.1387/ijdb.082669cp  1
2009 Kim HR, Ingham PW. The extracellular matrix protein TGFBI promotes myofibril bundling and muscle fibre growth in the zebrafish embryo. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 56-65. PMID 19097068 DOI: 10.1002/dvdy.21812  1
2009 Baxendale S, Chen CK, Tang H, Davison C, Hateren LV, Croning MD, Humphray SJ, Hubbard SJ, Ingham PW. Expression screening and annotation of a zebrafish myoblast cDNA library. Gene Expression Patterns : Gep. 9: 73-82. PMID 19007914 DOI: 10.1016/j.gep.2008.10.003  1
2008 Currie PD, Schilling TF, Ingham PW. Small-scale marker-based screening for mutations in zebrafish development. Methods in Molecular Biology (Clifton, N.J.). 461: 493-512. PMID 19030819 DOI: 10.1007/978-1-60327-483-8_34  0.4
2008 Chico TJ, Ingham PW, Crossman DC. Modeling cardiovascular disease in the zebrafish. Trends in Cardiovascular Medicine. 18: 150-5. PMID 18555188 DOI: 10.1016/j.tcm.2008.04.002  1
2008 von Hofsten J, Elworthy S, Gilchrist MJ, Smith JC, Wardle FC, Ingham PW. Prdm1- and Sox6-mediated transcriptional repression specifies muscle fibre type in the zebrafish embryo. Embo Reports. 9: 683-9. PMID 18535625 DOI: 10.1038/embor.2008.73  1
2008 Elworthy S, Hargrave M, Knight R, Mebus K, Ingham PW. Expression of multiple slow myosin heavy chain genes reveals a diversity of zebrafish slow twitch muscle fibres with differing requirements for Hedgehog and Prdm1 activity. Development (Cambridge, England). 135: 2115-26. PMID 18480160 DOI: 10.1242/dev.015719  1
2008 Flinn L, Bretaud S, Lo C, Ingham PW, Bandmann O. Zebrafish as a new animal model for movement disorders. Journal of Neurochemistry. 106: 1991-7. PMID 18466340 DOI: 10.1111/j.1471-4159.2008.05463.x  1
2008 Ingham PW. Hedgehog signalling. Current Biology : Cb. 18: R238-41. PMID 18364223 DOI: 10.1016/j.cub.2008.01.050  1
2008 Pagnon-Minot A, Malbouyres M, Haftek-Terreau Z, Kim HR, Sasaki T, Thisse C, Thisse B, Ingham PW, Ruggiero F, Le Guellec D. Collagen XV, a novel factor in zebrafish notochord differentiation and muscle development. Developmental Biology. 316: 21-35. PMID 18281032 DOI: 10.1016/j.ydbio.2007.12.033  1
2008 Parkin CA, Ingham PW. The adventures of Sonic Hedgehog in development and repair. I. Hedgehog signaling in gastrointestinal development and disease. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G363-7. PMID 18063705 DOI: 10.1152/ajpgi.00457.2007  1
2007 Renshaw SA, Loynes CA, Elworthy S, Ingham PW, Whyte MK. Modeling inflammation in the zebrafish: how a fish can help us understand lung disease. Experimental Lung Research. 33: 549-54. PMID 18075830 DOI: 10.1080/01902140701756778  1
2007 Brunk K, Vernay B, Griffith E, Reynolds NL, Strutt D, Ingham PW, Jackson AP. Microcephalin coordinates mitosis in the syncytial Drosophila embryo. Journal of Cell Science. 120: 3578-88. PMID 17895363 DOI: 10.1242/jcs.014290  1
2007 Moore CA, Parkin CA, Bidet Y, Ingham PW. A role for the Myoblast city homologues Dock1 and Dock5 and the adaptor proteins Crk and Crk-like in zebrafish myoblast fusion. Development (Cambridge, England). 134: 3145-53. PMID 17670792 DOI: 10.1242/dev.001214  1
2007 Gray C, Packham IM, Wurmser F, Eastley NC, Hellewell PG, Ingham PW, Crossman DC, Chico TJ. Ischemia is not required for arteriogenesis in zebrafish embryos. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 2135-41. PMID 17656667 DOI: 10.1161/ATVBAHA.107.143990  1
2007 Svetic V, Hollway GE, Elworthy S, Chipperfield TR, Davison C, Adams RJ, Eisen JS, Ingham PW, Currie PD, Kelsh RN. Sdf1a patterns zebrafish melanophores and links the somite and melanophore pattern defects in choker mutants. Development (Cambridge, England). 134: 1011-22. PMID 17267445 DOI: 10.1242/dev.02789  1
2007 Ingham P. Micromanaging the response to Hedgehog Nature Genetics. 39: 145-146. PMID 17262026 DOI: 10.1038/ng0207-145  1
2007 Bretaud S, Allen C, Ingham PW, Bandmann O. p53-dependent neuronal cell death in a DJ-1-deficient zebrafish model of Parkinson's disease. Journal of Neurochemistry. 100: 1626-35. PMID 17166173 DOI: 10.1111/j.1471-4159.2006.04291.x  1
2006 Ingham PW, Placzek M. Orchestrating ontogenesis: variations on a theme by sonic hedgehog. Nature Reviews. Genetics. 7: 841-50. PMID 17047684 DOI: 10.1038/nrg1969  1
2006 Renshaw SA, Loynes CA, Trushell DM, Elworthy S, Ingham PW, Whyte MK. A transgenic zebrafish model of neutrophilic inflammation. Blood. 108: 3976-8. PMID 16926288 DOI: 10.1182/blood-2006-05-024075  1
2005 Ingham PW, Kim HR. Hedgehog signalling and the specification of muscle cell identity in the zebrafish embryo. Experimental Cell Research. 306: 336-42. PMID 15925589 DOI: 10.1016/j.yexcr.2005.03.019  1
2005 Keegan BR, Feldman JL, Begemann G, Ingham PW, Yelon D. Retinoic acid signaling restricts the cardiac progenitor pool. Science (New York, N.Y.). 307: 247-9. PMID 15653502 DOI: 10.1126/science.1101573  1
2005 Tay SY, Ingham PW, Roy S. A homologue of the Drosophila kinesin-like protein Costal2 regulates Hedgehog signal transduction in the vertebrate embryo. Development (Cambridge, England). 132: 625-34. PMID 15647323 DOI: 10.1242/dev.01606  1
2004 Needham AJ, Kibart M, Crossley H, Ingham PW, Foster SJ. Drosophila melanogaster as a model host for Staphylococcus aureus infection. Microbiology (Reading, England). 150: 2347-55. PMID 15256576 DOI: 10.1099/mic.0.27116-0  1
2004 Nakano Y, Nystedt S, Shivdasani AA, Strutt H, Thomas C, Ingham PW. Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila. Mechanisms of Development. 121: 507-18. PMID 15172682 DOI: 10.1016/j.mod.2004.04.015  1
2004 Nakano Y, Kim HR, Kawakami A, Roy S, Schier AF, Ingham PW. Inactivation of dispatched 1 by the chameleon mutation disrupts Hedgehog signalling in the zebrafish embryo. Developmental Biology. 269: 381-92. PMID 15110707 DOI: 10.1016/j.ydbio.2004.01.022  1
2004 Baxendale S, Davison C, Muxworthy C, Wolff C, Ingham PW, Roy S. The B-cell maturation factor Blimp-1 specifies vertebrate slow-twitch muscle fiber identity in response to Hedgehog signaling. Nature Genetics. 36: 88-93. PMID 14702044 DOI: 10.1038/ng1280  0.32
2003 Thomas C, Ingham PW. Hedgehog signaling in the Drosophila eye and head: an analysis of the effects of different patched trans-heterozygotes. Genetics. 165: 1915-28. PMID 14704176  1
2003 Shivdasani AA, Ingham PW. Regulation of stem cell maintenance and transit amplifying cell proliferation by tgf-beta signaling in Drosophila spermatogenesis. Current Biology : Cb. 13: 2065-72. PMID 14653996 DOI: 10.1016/j.cub.2003.10.063  1
2003 Wolff C, Roy S, Ingham PW. Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the zebrafish embryo. Current Biology : Cb. 13: 1169-81. PMID 12867027 DOI: 10.1016/S0960-9822(03)00461-5  1
2003 Anderson KV, Ingham PW. The transformation of the model organism: a decade of developmental genetics. Nature Genetics. 33: 285-93. PMID 12610538 DOI: 10.1038/ng1105  1
2003 McMahon AP, Ingham PW, Tabin CJ. Developmental roles and clinical significance of hedgehog signaling. Current Topics in Developmental Biology. 53: 1-114. PMID 12509125  1
2002 Roy S, Ingham PW. Hedgehogs tryst with the cell cycle. Journal of Cell Science. 115: 4393-7. PMID 12414986 DOI: 10.1242/jcs.00158  1
2002 Begemann G, Gibert Y, Meyer A, Ingham PW. Cloning of zebrafish T-box genes tbx15 and tbx18 and their expression during embryonic development. Mechanisms of Development. 114: 137-41. PMID 12175500 DOI: 10.1016/S0925-4773(02)00040-0  1
2002 Glise B, Jones DL, Ingham PW. Notch and Wingless modulate the response of cells to Hedgehog signalling in the Drosophila wing. Developmental Biology. 248: 93-106. PMID 12142023 DOI: 10.1006/dbio.2002.0720  1
2001 Ingham PW, McMahon AP. Hedgehog signaling in animal development: paradigms and principles. Genes & Development. 15: 3059-87. PMID 11731473 DOI: 10.1101/gad.938601  1
2001 Ingham PW. Hedgehog signaling: a tale of two lipids. Science (New York, N.Y.). 294: 1879-81. PMID 11729305 DOI: 10.1126/science.1064115  1
2001 Begemann G, Schilling TF, Rauch GJ, Geisler R, Ingham PW. The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain. Development (Cambridge, England). 128: 3081-94. PMID 11688558  1
2001 Roy S, Qiao T, Wolff C, Ingham PW. Hedgehog signaling pathway is essential for pancreas specification in the zebrafish embryo. Current Biology : Cb. 11: 1358-63. PMID 11553330 DOI: 10.1016/S0960-9822(01)00402-X  1
2001 Roy S, Wolff C, Ingham PW. The u-boot mutation identifies a Hedgehog-regulated myogenic switch for fiber-type diversification in the zebrafish embryo. Genes & Development. 15: 1563-76. PMID 11410536 DOI: 10.1101/gad.195801  1
2001 Strutt H, Thomas C, Nakano Y, Stark D, Neave B, Taylor AM, Ingham PW. Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation. Current Biology : Cb. 11: 608-13. PMID 11369206 DOI: 10.1016/S0960-9822(01)00179-8  1
2001 Schilling TF, Prince V, Ingham PW. Plasticity in zebrafish hox expression in the hindbrain and cranial neural crest. Developmental Biology. 231: 201-16. PMID 11180963 DOI: 10.1006/dbio.2000.9997  1
2001 Currie PD, Ingham PW. 1. Induction and patterning of embryonic skeletal muscle cells in the zebrafish Fish Physiology. 18: 1-4,IN1-IN2,5-17. DOI: 10.1016/S1546-5098(01)18002-7  1
2000 Ingham PW, Nystedt S, Nakano Y, Brown W, Stark D, van den Heuvel M, Taylor AM. Patched represses the Hedgehog signalling pathway by promoting modification of the Smoothened protein. Current Biology : Cb. 10: 1315-8. PMID 11069117 DOI: 10.1016/S0960-9822(00)00755-7  1
2000 Norris W, Neyt C, Ingham PW, Currie PD. Slow muscle induction by Hedgehog signalling in vitro. Journal of Cell Science. 113: 2695-703. PMID 10893185  1
2000 Placzek M, Ingham PW. Developmental genetics in Sheffield: a meeting point for Hedgehog researchers. The International Journal of Developmental Biology. 44: 65-72. PMID 10761849  1
2000 Ingham PW. How cholesterol modulates the signal. Current Biology : Cb. 10: R180-3. PMID 10712894 DOI: 10.1016/S0960-9822(00)00346-8  1
2000 Odenthal J, van Eeden FJ, Haffter P, Ingham PW, Nüsslein-Volhard C. Two distinct cell populations in the floor plate of the zebrafish are induced by different pathways. Developmental Biology. 219: 350-63. PMID 10694427 DOI: 10.1006/dbio.1999.9589  1
2000 Begemann G, Ingham PW. Developmental regulation of Tbx5 in zebrafish embryogenesis. Mechanisms of Development. 90: 299-304. PMID 10640716 DOI: 10.1016/S0925-4773(99)00246-4  1
2000 Brown LA, Rodaway AR, Schilling TF, Jowett T, Ingham PW, Patient RK, Sharrocks AD. Insights into early vasculogenesis revealed by expression of the ETS-domain transcription factor Fli-1 in wild-type and mutant zebrafish embryos. Mechanisms of Development. 90: 237-52. PMID 10640707 DOI: 10.1016/S0925-4773(99)00256-7  1
2000 Ingham PW, Placzek M. Introduction: Preface to the Hedgehog family of proteins review volume Cellular and Molecular Life Sciences. 57: 1671.  1
1999 Lewis KE, Currie PD, Roy S, Schauerte H, Haffter P, Ingham PW. Control of muscle cell-type specification in the zebrafish embryo by Hedgehog signalling. Developmental Biology. 216: 469-80. PMID 10642786 DOI: 10.1006/dbio.1999.9519  1
1999 Currie PD, Schilling TF, Ingham PW. Small-scale marker-based screening for mutations in zebrafish development. Methods in Molecular Biology (Clifton, N.J.). 97: 441-60. PMID 10443384 DOI: 10.1385/1-59259-270-8:441  1
1999 Cunliffe VT, Ingham PW. Switching on the notochord. Genes & Development. 13: 1643-6. PMID 10398677  1
1999 Schilling TF, Concordet JP, Ingham PW. Regulation of left-right asymmetries in the zebrafish by Shh and BMP4. Developmental Biology. 210: 277-87. PMID 10357891 DOI: 10.1006/dbio.1999.9214  1
1999 Lewis KE, Drossopoulou G, Paton IR, Morrice DR, Robertson KE, Burt DW, Ingham PW, Tickle C. Expression of ptc and gli genes in talpid3 suggests bifurcation in Shh pathway. Development (Cambridge, England). 126: 2397-407. PMID 10225999  1
1999 Lewis KE, Concordet JP, Ingham PW. Characterisation of a second patched gene in the zebrafish Danio rerio and the differential response of patched genes to Hedgehog signalling. Developmental Biology. 208: 14-29. PMID 10075838 DOI: 10.1006/dbio.1998.9169  1
1998 Ingham PW. Boning up on Hedgehog's movements. Nature. 394: 16-7. PMID 9665119 DOI: 10.1038/27764  1
1998 Ingham PW. trithorax and the regulation of homeotic gene expression in Drosophila: a historical perspective. The International Journal of Developmental Biology. 42: 423-9. PMID 9654027  1
1998 Ingham PW. Transducing Hedgehog: the story so far. The Embo Journal. 17: 3505-11. PMID 9649421 DOI: 10.1093/emboj/17.13.3505  1
1998 Currie PD, Ingham PW. The generation and interpretation of positional information within the vertebrate myotome. Mechanisms of Development. 73: 3-21. PMID 9545513 DOI: 10.1016/S0925-4773(98)00036-7  1
1998 Ingham PW. The patched gene in development and cancer. Current Opinion in Genetics & Development. 8: 88-94. PMID 9529611 DOI: 10.1016/S0959-437X(98)80067-1  1
1998 Ingham PW. Corrigendum: The patched gene in development and cancer (Current Opinion in Genetics and Development (1988) 8 (88-94)) Current Opinion in Genetics and Development. 8: 371. DOI: 10.1016/S0959-437X(98)80096-8  1
1997 Strähle U, Jesuthasan S, Blader P, Garcia-Villalba P, Hatta K, Ingham PW. one-eyed pinhead is required for development of the ventral midline of the zebrafish (Danio rerio) neural tube. Genes and Function. 1: 131-48. PMID 9680314  1
1997 Rauch GJ, Hammerschmidt M, Blader P, Schauerte HE, Strähle U, Ingham PW, McMahon AP, Haffter P. Wnt5 is required for tail formation in the zebrafish embryo. Cold Spring Harbor Symposia On Quantitative Biology. 62: 227-34. PMID 9598355  1
1997 Quirk J, van den Heuvel M, Henrique D, Marigo V, Jones TA, Tabin C, Ingham PW. The smoothened gene and hedgehog signal transduction in Drosophila and vertebrate development. Cold Spring Harbor Symposia On Quantitative Biology. 62: 217-26. PMID 9598354  1
1997 Blagden CS, Currie PD, Ingham PW, Hughes SM. Notochord induction of zebrafish slow muscle mediated by Sonic hedgehog. Genes & Development. 11: 2163-75. PMID 9303533  1
1997 Ingham PW. Zebrafish genetics and its implications for understanding vertebrate development. Human Molecular Genetics. 6: 1755-60. PMID 9300668 DOI: 10.1093/hmg/6.10.1755  1
1997 Chang BE, Blader P, Fischer N, Ingham PW, Strähle U. Axial (HNF3beta) and retinoic acid receptors are regulators of the zebrafish sonic hedgehog promoter. The Embo Journal. 16: 3955-64. PMID 9233805 DOI: 10.1093/emboj/16.13.3955  1
1996 Blader P, Strähle U, Ingham PW. Three Wnt genes expressed in a wide variety of tissues during development of the zebrafish, Danio rerio: developmental and evolutionary perspectives. Development Genes and Evolution. 206: 3-13. PMID 24173392 DOI: 10.1007/s004270050025  1
1996 van den Heuvel M, Ingham PW. 'Smoothening' the path for hedgehogs. Trends in Cell Biology. 6: 451-3. PMID 15157500 DOI: 10.1016/0962-8924(96)84934-8  1
1996 Strähle U, Blader P, Ingham PW. Expression of axial and sonic hedgehog in wildtype and midline defective zebrafish embryos. The International Journal of Developmental Biology. 40: 929-40. PMID 8946241  1
1996 Ingham PW. Has the quest for a Wnt receptor finally frizzled out? Trends in Genetics : Tig. 12: 382-4. PMID 8909125 DOI: 10.1016/0168-9525(96)30096-6  1
1996 Forbes AJ, Spradling AC, Ingham PW, Lin H. The role of segment polarity genes during early oogenesis in Drosophila. Development (Cambridge, England). 122: 3283-94. PMID 8898240  1
1996 Concordet JP, Lewis KE, Moore JW, Goodrich LV, Johnson RL, Scott MP, Ingham PW. Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning. Development (Cambridge, England). 122: 2835-46. PMID 8787757  1
1996 Alexandre C, Jacinto A, Ingham PW. Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins. Genes & Development. 10: 2003-13. PMID 8769644  1
1996 Van den Heuvel M, Ingham PW. Smoothened encodes a receptor-like serpentine protein required for hedgehog signalling Nature. 382: 547-551. PMID 8700230 DOI: 10.1038/382547a0  1
1996 Currie PD, Ingham PW. Induction of a specific muscle cell type by a hedgehog-like protein in zebrafish Nature. 382: 452-455. PMID 8684485 DOI: 10.1038/382452a0  1
1996 Forbes AJ, Lin H, Ingham PW, Spradling AC. hedgehog is required for the proliferation and specification of ovarian somatic cells prior to egg chamber formation in Drosophila. Development (Cambridge, England). 122: 1125-35. PMID 8620839  1
1996 Currie PD, Jacinto A, Ingham PW. Hedgehog signalling in Drosophila and vertebrate development Netherlands Journal of Zoology. 46: 97-114.  1
1996 Blader P, Strähle U, Ingham PW. Three Wnt genes expressed in a wide variety of tissues during development of the zebrafish, Danio rerio: Developmental and evolutionary perspectives Roux's Archives of Developmental Biology. 206: 3-13.  1
1995 Ingham PW, Fietz MJ. Quantitative effects of hedgehog and decapentaplegic activity on the patterning of the Drosophila wing Current Biology. 5: 432-440. PMID 7627558 DOI: 10.1016/S0960-9822(95)00084-4  1
1995 Ingham PW. Signalling by hedgehog family proteins in Drosophila and vertebrate development Current Opinion in Genetics and Development. 5: 492-498. PMID 7580142 DOI: 10.1016/0959-437X(95)90054-K  1
1995 Fietz MJ, Jacinto A, Taylor AM, Alexandre C, Ingham PW. Secretion of the amino-terminal fragment of the hedgehog protein is necessary and sufficient for hedgehog signalling in Drosophila. Current Biology : Cb. 5: 643-50. PMID 7552175 DOI: 10.1016/S0960-9822(95)00129-1  1
1994 Strähle U, Blader P, Adam J, Ingham PW. A simple and efficient procedure for non-isotopic in situ hybridization to sectioned material. Trends in Genetics : Tig. 10: 75-6. PMID 8178367 DOI: 10.1016/0168-9525(94)90221-6  1
1994 Paroush Z, Finley RL, Kidd T, Wainwright SM, Ingham PW, Brent R, Ish-Horowicz D. Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins. Cell. 79: 805-15. PMID 8001118 DOI: 10.1016/0092-8674(94)90070-1  1
1994 Ingham PW. Pattern Formation: Hedgehog points the way Current Biology. 4: 347-350. PMID 7922344 DOI: 10.1016/S0960-9822(00)00076-2  1
1994 Fietz MJ, Concordet JP, Barbosa R, Johnson R, Krauss S, McMahon AP, Tabin C, Ingham PW. The hedgehog gene family in Drosophila and vertebrate development. Development (Cambridge, England). Supplement. 43-51. PMID 7579523  1
1994 Fietz MJ, Concordet JP, Barbosa R, Johnson R, Krauss S, McMahon AP, Tabin C, Ingham PW. The hedgehog gene family in Drosophila and vertebrate development Development. 120: 43-51.  1
1993 Forbes AJ, Nakano Y, Taylor AM, Ingham PW. Genetic analysis of hedgehog signalling in the Drosophila embryo. Development (Cambridge, England). 119: 115-24. PMID 27002038  0.96
1993 Taylor AM, Nakano Y, Mohler J, Ingham PW. Contrasting distributions of patched and hedgehog proteins in the Drosophila embryo. Mechanisms of Development. 42: 89-96. PMID 8369225 DOI: 10.1016/0925-4773(93)90101-3  1
1993 Krauss S, Concordet JP, Ingham PW. A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos Cell. 75: 1431-1444. PMID 8269519 DOI: 10.1016/0092-8674(93)90628-4  1
1993 Ingham PW. Localized hedgehog activity controls spatial limits of wingless transcription in the Drosophila embryo Nature. 366: 560-562. PMID 8255293 DOI: 10.1038/366560a0  1
1993 Ingham PW, Hidalgo A. Regulation of wingless transcription in the Drosophila embryo. Development (Cambridge, England). 117: 283-91. PMID 8223252  1
1993 Forbes AJ, Nakano Y, Taylor AM, Ingham PW. Genetic analysis of hedgehog signalling in the Drosophila embryo. Development (Cambridge, England). Supplement. 115-24. PMID 8049467  1
1993 Strähle U, Blader P, Henrique D, Ingham PW. Axial, a zebrafish gene expressed along the developing body axis, shows altered expression in cyclops mutant embryos. Genes & Development. 7: 1436-46. PMID 7687227  1
1992 Eisenberg LM, Ingham PW, Brown AMC. Cloning and characterization of a novel Drosophila Wnt gene, Dwnt-5, a putative downstream target of the homeobox gene Distal-less Developmental Biology. 154: 73-83. PMID 1358729 DOI: 10.1016/0012-1606(92)90049-M  1
1992 Ingham PW, Martinez Arias A. Boundaries and fields in early embryos. Cell. 68: 221-35. PMID 1346367 DOI: 10.1016/0092-8674(92)90467-Q  1
1992 Strähle U, Ingham PW. Flight of fancy or a major new school? Current Biology. 2: 135-138. DOI: 10.1016/0960-9822(92)90256-A  1
1991 Ingham PW. Segment polarity genes and cell patterning within the Drosophila body segment Current Opinion in Genetics and Development. 1: 261-267. PMID 1688007 DOI: 10.1016/S0959-437X(05)80080-2  1
1991 Ingham PW, Taylor AM, Nakano Y. Role of the Drosophila patched gene in positional signalling. Nature. 353: 184-7. PMID 1653906 DOI: 10.1038/353184a0  1
1990 Phillips RG, Roberts IJ, Ingham PW, Whittle JR. The Drosophila segment polarity gene patched is involved in a position-signalling mechanism in imaginal discs. Development (Cambridge, England). 110: 105-14. PMID 2081453  1
1990 Ingham PW. The X, Y, Z of head development Nature. 346: 412-413. PMID 1974031 DOI: 10.1038/346412a0  1
1990 Ingham PW, Nakano Y. Cell patterning and segment polarity genes in Drosophila Development Growth and Differentiation. 32: 563-574.  1
1989 Nakano Y, Guerrero I, Hidalgo A, Taylor A, Whittle JR, Ingham PW. A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched. Nature. 341: 508-13. PMID 2797178 DOI: 10.1038/341508a0  1
1989 Ingham PW. Drosophila development Current Opinion in Cell Biology. 1: 1127-1131. PMID 2576860 DOI: 10.1016/S0955-0674(89)80061-4  1
1989 Ish-Horowicz D, Pinchin SM, Ingham PW, Gyurkovics HG. Autocatalytic ftz activation and metameric instability induced by ectopic ftz expression. Cell. 57: 223-32. PMID 2495181 DOI: 10.1016/0092-8674(89)90960-4  1
1988 Arias AM, Baker NE, Ingham PW. Role of segment polarity genes in the definition and maintenance of cell states in the Drosophila embryo Development. 103: 157-170. PMID 3197626  1
1988 Ingham PW. The molecular genetics of embryonic pattern formation in Drosophila Nature. 335: 25-34. PMID 2901040  1
1988 Ingham PW, Baker NE, Martinez-Arias A. Regulation of segment polarity genes in the Drosophila blastoderm by fushi tarazu and even skipped. Nature. 331: 73-5. PMID 2893285 DOI: 10.1038/331073a0  1
1987 Martinez-Arias A, Ingham PW, Scott MP, Akam ME. The spatial and temporal deployment of Dfd and Scr transcripts throughout development of Drosophila. Development (Cambridge, England). 100: 673-83. PMID 2450726  1
1986 Ingham PW, Ish-Horowicz D, Howard KR. Correlative changes in homoeotic and segmentation gene expression in Krüppel mutant embryos of Drosophila. The Embo Journal. 5: 1659-65. PMID 16453692  1
1986 Ingham PW, Martinez-Arias A. The correct activation of Antennapedia and bithorax complex genes requires the fushi tarazu gene. Nature. 324: 592-7. PMID 2878371 DOI: 10.1038/324592a0  1
1985 Ingham PW, Pinchin SM, Howard KR, Ish-Horowicz D. Genetic Analysis of the Hairy Locus in DROSOPHILA MELANOGASTER. Genetics. 111: 463-86. PMID 17246301  1
1985 Ingham PW. A clonal analysis of the requirement for the trithorax gene in the diversification of segments in Drosophila Journal of Embryology and Experimental Morphology. 349-365. PMID 4093752  1
1985 Martinez-Arias A, Ingham PW. The origin of pattern duplications in segment polarity mutants of Drosophila melanogaster. Journal of Embryology and Experimental Morphology. 87: 129-35. PMID 3928797  1
1985 Ish-Horowicz D, Howard KR, Pinchin SM, Ingham PW. Molecular and genetic analysis of the hairy locus in Drosophila. Cold Spring Harbor Symposia On Quantitative Biology. 50: 135-44. PMID 3006986  1
1985 Ingham PW. Genetic control of the spatial pattern of selector gene expression in Drosophila Cold Spring Harbor Symposia On Quantitative Biology. 50: 201-208. PMID 2420511  1
1985 Ingham PW, Howard KR, Ish-Horowicz D. Transcription pattern of the Drosophila segmentation gene hairy Nature. 318: 439-445. DOI: 10.1038/318439a0  1
1985 Ingham PW. Drosophila genetics: Patterns of differentiation Nature. 317: 202-203. DOI: 10.1038/317202a0  1
1984 Ingham PW. A gene that regulates the bithorax complex differentially in larval and adult cells of Drosophila Cell. 37: 815-823. PMID 6430566 DOI: 10.1016/0092-8674(84)90416-1  1
1983 Ingham PW. Differential expression of bithorax complex genes in the absence of the extra sex combs and trithorax genes Nature. 306: 591-593.  1
1981 Ingham PW. Trithorax: A new homoeotic mutation of Drosophila melanogaster - II. The role of trx+ after embryogenesis Wilhelm Roux's Archives of Developmental Biology. 190: 365-369. DOI: 10.1007/BF00863275  1
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