Linda Partridge - Publications

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234 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Juricic P, Grönke S, Partridge L. Branched-chain amino acids have equivalent effects to other essential amino acids on lifespan and ageing-related traits in Drosophila. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 30891588 DOI: 10.1093/gerona/glz080  0.32
2019 Weigelt CM, Hahn O, Arlt K, Gruhn M, Jahn AJ, Eßer J, Werner JA, Klein C, Büschges A, Grönke S, Partridge L. Loss of miR-210 leads to progressive retinal degeneration in . Life Science Alliance. 2. PMID 30670478 DOI: 10.26508/lsa.201800149  0.32
2019 Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L. Using the drug-protein interactome to identify anti-ageing compounds for humans. Plos Computational Biology. 15: e1006639. PMID 30625143 DOI: 10.1371/journal.pcbi.1006639  0.44
2019 Moens TG, Niccoli T, Wilson KM, Atilano ML, Birsa N, Gittings LM, Holbling BV, Dyson MC, Thoeng A, Neeves J, Glaria I, Yu L, Bussmann J, Storkebaum E, Pardo M, ... ... Partridge L, et al. C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A. Acta Neuropathologica. PMID 30604225 DOI: 10.1007/s00401-018-1946-4  0.44
2018 Dönertaş HM, Fuentealba M, Partridge L, Thornton JM. Identifying Potential Ageing-Modulating Drugs In Silico. Trends in Endocrinology and Metabolism: Tem. PMID 30581056 DOI: 10.1016/j.tem.2018.11.005  0.44
2018 Hahn O, Stubbs TM, Reik W, Grönke S, Beyer A, Partridge L. Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity. Plos Genetics. 14: e1007766. PMID 30462643 DOI: 10.1371/journal.pgen.1007766  0.32
2018 Kauppila TES, Bratic A, Jensen MB, Baggio F, Partridge L, Jasper H, Grönke S, Larsson NG. Mutations of mitochondrial DNA are not major contributors to aging of fruit flies. Proceedings of the National Academy of Sciences of the United States of America. PMID 30249665 DOI: 10.1073/pnas.1721683115  0.32
2018 Dönertaş HM, Fuentealba Valenzuela M, Partridge L, Thornton JM. Gene Expression-Based Drug Repurposing to Target Ageing. Aging Cell. e12819. PMID 29959820 DOI: 10.1111/acel.12819  0.44
2018 Catterson JH, Khericha M, Dyson MC, Vincent AJ, Callard R, Haveron SM, Rajasingam A, Ahmad M, Partridge L. Short-Term, Intermittent Fasting Induces Long-Lasting Gut Health and TOR-Independent Lifespan Extension. Current Biology : Cb. PMID 29779873 DOI: 10.1016/j.cub.2018.04.015  0.44
2018 Augustin H, McGourty K, Allen MJ, Adcott J, Wong CT, Boucrot E, Partridge L. Impact of insulin signaling and proteasomal activity on physiological output of a neuronal circuit in aging Drosophila melanogaster. Neurobiology of Aging. 66: 149-157. PMID 29579685 DOI: 10.1016/j.neurobiolaging.2018.02.027  0.44
2018 Moens TG, Mizielinska S, Niccoli T, Mitchell JS, Thoeng A, Ridler CE, Grönke S, Esser J, Heslegrave A, Zetterberg H, Partridge L, Isaacs AM. Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTD. Acta Neuropathologica. PMID 29380049 DOI: 10.1007/s00401-017-1798-3  0.44
2017 Simone R, Balendra R, Moens TG, Preza E, Wilson KM, Heslegrave A, Woodling NS, Niccoli T, Gilbert-Jaramillo J, Abdelkarim S, Clayton EL, Clarke M, Konrad MT, Nicoll AJ, Mitchell JS, ... ... Partridge L, et al. G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo. Embo Molecular Medicine. PMID 29113975 DOI: 10.15252/emmm.201707850  0.44
2017 Bolukbasi E, Khericha M, Regan JC, Ivanov DK, Adcott J, Dyson MC, Nespital T, Thornton JM, Alic N, Partridge L. Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity. Cell Reports. 21: 641-653. PMID 29045833 DOI: 10.1016/j.celrep.2017.09.042  1
2017 Niccoli T, Partridge L, Isaacs AM. Ageing as a risk factor for ALS/FTD. Human Molecular Genetics. 26: R105-R113. PMID 28977441 DOI: 10.1093/hmg/ddx247  0.44
2017 Piper MDW, Partridge L. Drosophila as a model for ageing. Biochimica Et Biophysica Acta. PMID 28964875 DOI: 10.1016/j.bbadis.2017.09.016  0.6
2017 Tain LS, Sehlke R, Jain C, Chokkalingam M, Nagaraj N, Essers P, Rassner M, Grönke S, Froelich J, Dieterich C, Mann M, Alic N, Beyer A, Partridge L. A proteomic atlas of insulin signalling reveals tissue-specific mechanisms of longevity assurance. Molecular Systems Biology. 13: 939. PMID 28916541  1
2017 Augustin H, McGourty K, Allen MJ, Madem SK, Adcott J, Kerr F, Wong CT, Vincent A, Godenschwege T, Boucrot E, Partridge L. Reduced insulin signaling maintains electrical transmission in a neural circuit in aging flies. Plos Biology. 15: e2001655. PMID 28902870 DOI: 10.1371/journal.pbio.2001655  0.44
2017 Gorsky MK, Burnouf S, Sofola-Adesakin O, Dols J, Augustin H, Weigelt CM, Grönke S, Partridge L. Pseudo-acetylation of multiple sites on human Tau proteins alters Tau phosphorylation and microtubule binding, and ameliorates amyloid beta toxicity. Scientific Reports. 7: 9984. PMID 28855586 DOI: 10.1038/s41598-017-10225-0  0.32
2017 Augustin H, Adcott J, Elliott CJH, Partridge L. Complex Roles of Myoglianin in Regulating Adult Performance and Lifespan. Fly. 0. PMID 28837401 DOI: 10.1080/19336934.2017.1369638  0.44
2017 Ziehm M, Kaur S, Ivanov DK, Ballester PJ, Marcus D, Partridge L, Thornton JM. Drug repurposing for aging research using model organisms. Aging Cell. PMID 28620943 DOI: 10.1111/acel.12626  0.44
2017 Zhao Y, Gilliat AF, Ziehm M, Turmaine M, Wang H, Ezcurra M, Yang C, Phillips G, McBay D, Zhang WB, Partridge L, Pincus Z, Gems D. Two forms of death in ageing Caenorhabditis elegans. Nature Communications. 8: 15458. PMID 28534519 DOI: 10.1038/ncomms15458  0.48
2017 Augustin H, McGourty K, Steinert JR, Cochemé HM, Adcott J, Cabecinha M, Vincent A, Halff EF, Kittler JT, Boucrot E, Partridge L. Myostatin-like proteins regulate synaptic function and neuronal morphology. Development (Cambridge, England). PMID 28533206 DOI: 10.1242/dev.152975  0.44
2017 Piper MDW, Soultoukis GA, Blanc E, Mesaros A, Herbert SL, Juricic P, He X, Atanassov I, Salmonowicz H, Yang M, Simpson SJ, Ribeiro C, Partridge L. Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan. Cell Metabolism. 25: 1206. PMID 28467937 DOI: 10.1016/j.cmet.2017.04.020  0.6
2017 Hahn O, Grönke S, Stubbs TM, Ficz G, Hendrich O, Krueger F, Andrews S, Zhang Q, Wakelam MJ, Beyer A, Reik W, Partridge L. Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism. Genome Biology. 18: 56. PMID 28351387 DOI: 10.1186/s13059-017-1187-1  0.32
2017 Piper MD, Soultoukis GA, Blanc E, Mesaros A, Herbert SL, Juricic P, He X, Atanassov I, Salmonowicz H, Yang M, Simpson SJ, Ribeiro C, Partridge L. Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan. Cell Metabolism. 25: 610-621. PMID 28273481 DOI: 10.1016/j.cmet.2017.02.005  0.84
2017 Kerr F, Sofola-Adesakin O, Ivanov DK, Gatliff J, Gomez Perez-Nievas B, Bertrand HC, Martinez P, Callard R, Snoeren I, Cochemé HM, Adcott J, Khericha M, Castillo-Quan JI, Wells G, Noble W, ... ... Partridge L, et al. Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer's disease. Plos Genetics. 13: e1006593. PMID 28253260 DOI: 10.1371/journal.pgen.1006593  0.44
2016 Kinghorn KJ, Grönke S, Castillo-Quan JI, Woodling NS, Li L, Sirka E, Gegg M, Mills K, Hardy J, Bjedov I, Partridge L. A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 11654-11670. PMID 27852774 DOI: 10.1523/JNEUROSCI.4527-15.2016  1
2016 Piper MD, Partridge L. Protocols to Study Aging in Drosophila. Methods in Molecular Biology (Clifton, N.J.). 1478: 291-302. PMID 27730590 DOI: 10.1007/978-1-4939-6371-3_18  0.84
2016 Sofola-Adesakin O, Khericha M, Snoeren I, Tsuda L, Partridge L. pGluAβ increases accumulation of Aβ in vivo and exacerbates its toxicity. Acta Neuropathologica Communications. 4: 109. PMID 27717375 DOI: 10.1186/s40478-016-0380-x  0.44
2016 Kakanj P, Moussian B, Grönke S, Bustos V, Eming SA, Partridge L, Leptin M. Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing. Nature Communications. 7: 12972. PMID 27713427 DOI: 10.1038/ncomms12972  0.32
2016 Niccoli T, Cabecinha M, Tillmann A, Kerr F, Wong CT, Cardenes D, Vincent AJ, Bettedi L, Li L, Grönke S, Dols J, Partridge L. Increased Glucose Transport into Neurons Rescues Aβ Toxicity in Drosophila. Current Biology : Cb. 26: 2550. PMID 27676294 DOI: 10.1016/j.cub.2016.09.018  0.44
2016 Niccoli T, Cabecinha M, Tillmann A, Kerr F, Wong CT, Cardenes D, Vincent AJ, Bettedi L, Li L, Grönke S, Dols J, Partridge L. Increased Glucose Transport into Neurons Rescues Aβ Toxicity in Drosophila. Current Biology : Cb. PMID 27524482 DOI: 10.1016/j.cub.2016.07.017  0.44
2016 Essers P, Tain LS, Nespital T, Goncalves J, Froehlich J, Partridge L. Reduced insulin/insulin-like growth factor signaling decreases translation in Drosophila and mice. Scientific Reports. 6: 30290. PMID 27452396 DOI: 10.1038/srep30290  0.44
2016 Castillo-Quan JI, Li L, Kinghorn KJ, Ivanov DK, Tain LS, Slack C, Kerr F, Nespital T, Thornton J, Hardy J, Bjedov I, Partridge L. Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis. Cell Reports. PMID 27068460 DOI: 10.1016/j.celrep.2016.03.041  1
2016 Iyer J, Wang Q, Le T, Pizzo L, Grönke S, Ambegaokar S, Imai Y, Srivastava A, Llamusí Troisí B, Mardon G, Artero R, Jackson GR, Isaacs AM, Partridge L, Kumar JP, et al. Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster. G3 (Bethesda, Md.). PMID 26994292 DOI: 10.1534/g3.116.027060  0.32
2016 Burnouf S, Grönke S, Augustin H, Dols J, Gorsky MK, Werner J, Kerr F, Alic N, Martinez P, Partridge L. Deletion of endogenous Tau proteins is not detrimental in Drosophila. Scientific Reports. 6: 23102. PMID 26976084 DOI: 10.1038/srep23102  1
2016 Regan JC, Khericha M, Dobson AJ, Bolukbasi E, Rattanavirotkul N, Partridge L. Sex difference in pathology of the ageing gut mediates the greater response of female lifespan to dietary restriction. Elife. 5. PMID 26878754 DOI: 10.7554/eLife.10956  0.52
2016 Afschar S, Toivonen JM, Hoffmann JM, Tain LS, Wieser D, Finlayson AJ, Driege Y, Alic N, Emran S, Stinn J, Froehlich J, Piper MD, Partridge L. Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787908 DOI: 10.1073/pnas.1515137113  1
2015 Menger KE, James AM, Cochemé HM, Harbour ME, Chouchani ET, Ding S, Fearnley IM, Partridge L, Murphy MP. Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster. Cell Reports. 13: 1285. PMID 28873344 DOI: 10.1016/j.celrep.2015.10.048  0.32
2015 Logan A, Pell VR, Shaffer KJ, Evans C, Stanley NJ, Robb EL, Prime TA, Chouchani ET, Cochemé HM, Fearnley IM, Vidoni S, James AM, Porteous CM, Partridge L, Krieg T, et al. Assessing the Mitochondrial Membrane Potential in Cells and In Vivo using Targeted Click Chemistry and Mass Spectrometry. Cell Metabolism. PMID 26712463 DOI: 10.1016/j.cmet.2015.11.014  1
2015 Armanios M, de Cabo R, Mannick J, Partridge L, van Deursen J, Villeda S. Translational strategies in aging and age-related disease. Nature Medicine. 21: 1395-9. PMID 26646495 DOI: 10.1038/nm.4004  1
2015 Slack C, Alic N, Partridge L. Could cancer drugs provide ammunition against ageing? Cell Cycle (Georgetown, Tex.). 0. PMID 26587873 DOI: 10.1080/15384101.2015.1118905  1
2015 Bratic A, Kauppila TE, Macao B, Grönke S, Siibak T, Stewart JB, Baggio F, Dols J, Partridge L, Falkenberg M, Wredenberg A, Larsson NG. Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies. Nature Communications. 6: 8808. PMID 26554610 DOI: 10.1038/ncomms9808  1
2015 Knuever J, Willenborg S, Ding X, Akyüz MD, Partridge L, Niessen CM, Brüning JC, Eming SA. Myeloid Cell-Restricted Insulin/IGF-1 Receptor Deficiency Protects against Skin Inflammation. Journal of Immunology (Baltimore, Md. : 1950). PMID 26519530 DOI: 10.4049/jimmunol.1501237  1
2015 Hoffmann JM, Partridge L. Nuclear hormone receptors: Roles of xenobiotic detoxification and sterol homeostasis in healthy aging. Critical Reviews in Biochemistry and Molecular Biology. 50: 380-92. PMID 26383043 DOI: 10.3109/10409238.2015.1067186  1
2015 Ziehm M, Ivanov DK, Bhat A, Partridge L, Thornton JM. SurvCurv database and online survival analysis platform update. Bioinformatics (Oxford, England). PMID 26249811 DOI: 10.1093/bioinformatics/btv463  1
2015 Slack C, Alic N, Foley A, Cabecinha M, Hoddinott MP, Partridge L. The Ras-Erk-ETS-Signaling Pathway Is a Drug Target for Longevity. Cell. 162: 72-83. PMID 26119340 DOI: 10.1016/j.cell.2015.06.023  1
2015 Menger KE, James AM, Cochemé HM, Harbour ME, Chouchani ET, Ding S, Fearnley IM, Partridge L, Murphy MP. Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster. Cell Reports. 11: 1856-65. PMID 26095360 DOI: 10.1016/j.celrep.2015.05.033  1
2015 Kinghorn KJ, Castillo-Quan JI, Bartolome F, Angelova PR, Li L, Pope S, Cochemé HM, Khan S, Asghari S, Bhatia KP, Hardy J, Abramov AY, Partridge L. Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction. Brain : a Journal of Neurology. 138: 1801-16. PMID 26001724 DOI: 10.1093/brain/awv132  1
2015 Ivanov DK, Escott-Price V, Ziehm M, Magwire MM, Mackay TF, Partridge L, Thornton JM. Longevity GWAS Using the Drosophila Genetic Reference Panel. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25922346 DOI: 10.1093/gerona/glv047  1
2015 Burnouf S, Gorsky MK, Dols J, Grönke S, Partridge L. Aβ43 is neurotoxic and primes aggregation of Aβ40 in vivo. Acta Neuropathologica. 130: 35-47. PMID 25862636 DOI: 10.1007/s00401-015-1419-y  1
2015 Fontana L, Partridge L. Promoting health and longevity through diet: from model organisms to humans. Cell. 161: 106-18. PMID 25815989 DOI: 10.1016/j.cell.2015.02.020  1
2015 Partridge L. Celebrating 350 years of Philosophical Transactions: life sciences papers. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370. PMID 25750243 DOI: 10.1098/rstb.2014.0380  1
2015 Alic N, Partridge L. Myc mouse and anti-ageing therapy. Trends in Endocrinology and Metabolism: Tem. 26: 163-4. PMID 25727046 DOI: 10.1016/j.tem.2015.02.005  1
2014 Baggio F, Bratic A, Mourier A, Kauppila TE, Tain LS, Kukat C, Habermann B, Partridge L, Larsson NG. Drosophila melanogaster LRPPRC2 is involved in coordination of mitochondrial translation. Nucleic Acids Research. 42: 13920-38. PMID 25428350 DOI: 10.1093/nar/gku1132  1
2014 Piper MD, Selman C, Speakman JR, Partridge L. Using doubly-labeled water to measure energy expenditure in an important small ectotherm Drosophila melanogaster. Journal of Genetics and Genomics = Yi Chuan Xue Bao. 41: 505-12. PMID 25269676 DOI: 10.1016/j.jgg.2014.07.004  1
2014 Alic N, Giannakou ME, Papatheodorou I, Hoddinott MP, Andrews TD, Bolukbasi E, Partridge L. Interplay of dFOXO and two ETS-family transcription factors determines lifespan in Drosophila melanogaster. Plos Genetics. 10: e1004619. PMID 25232726 DOI: 10.1371/journal.pgen.1004619  1
2014 Partridge L. Intervening in ageing to prevent the diseases of ageing. Trends in Endocrinology and Metabolism: Tem. 25: 555-7. PMID 25175302 DOI: 10.1016/j.tem.2014.08.003  1
2014 Sofola-Adesakin O, Castillo-Quan JI, Rallis C, Tain LS, Bjedov I, Rogers I, Li L, Martinez P, Khericha M, Cabecinha M, Bähler J, Partridge L. Lithium suppresses Aβ pathology by inhibiting translation in an adult Drosophila model of Alzheimer's disease. Frontiers in Aging Neuroscience. 6: 190. PMID 25126078 DOI: 10.3389/fnagi.2014.00190  1
2014 Mizielinska S, Grönke S, Niccoli T, Ridler CE, Clayton EL, Devoy A, Moens T, Norona FE, Woollacott IO, Pietrzyk J, Cleverley K, Nicoll AJ, Pickering-Brown S, Dols J, Cabecinha M, ... ... Partridge L, et al. C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins. Science (New York, N.Y.). 345: 1192-4. PMID 25103406 DOI: 10.1126/science.1256800  1
2014 Metaxakis A, Tain LS, Grönke S, Hendrich O, Hinze Y, Birras U, Partridge L. Lowered insulin signalling ameliorates age-related sleep fragmentation in Drosophila. Plos Biology. 12: e1001824. PMID 24690889 DOI: 10.1371/journal.pbio.1001824  1
2014 Mauer J, Chaurasia B, Goldau J, Vogt MC, Ruud J, Nguyen KD, Theurich S, Hausen AC, Schmitz J, Brönneke HS, Estevez E, Allen TL, Mesaros A, Partridge L, Febbraio MA, et al. Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin. Nature Immunology. 15: 423-30. PMID 24681566 DOI: 10.1038/ni.2865  1
2014 Alic N, Tullet JM, Niccoli T, Broughton S, Hoddinott MP, Slack C, Gems D, Partridge L. Cell-nonautonomous effects of dFOXO/DAF-16 in aging. Cell Reports. 6: 608-16. PMID 24508462 DOI: 10.1016/j.celrep.2014.01.015  1
2014 Partridge L. Editorial 2014. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369: 20130496. PMID 24298168 DOI: 10.1098/rstb.2013.0496  1
2014 Piper MD, Blanc E, Leitão-Gonçalves R, Yang M, He X, Linford NJ, Hoddinott MP, Hopfen C, Soultoukis GA, Niemeyer C, Kerr F, Pletcher SD, Ribeiro C, Partridge L. A holidic medium for Drosophila melanogaster. Nature Methods. 11: 100-5. PMID 24240321 DOI: 10.1038/nmeth.2731  1
2014 Piper MDW, Blanc E, Leitão-Gonçalves R, Yang M, He X, Linford NJ, Hoddinott MP, Hopfen C, Soultoukis GA, Niemeyer C, Kerr F, Pletcher SD, Ribeiro C, Partridge L. Corrigendum: A holidic medium for Drosophila melanogaster (Nature Methods (2014) 11, (100-105)) Nature Methods. 11: 971. DOI: 10.1038/nmeth0914-971c  1
2013 Regan JC, Partridge L. Gender and longevity: why do men die earlier than women? Comparative and experimental evidence. Best Practice & Research. Clinical Endocrinology & Metabolism. 27: 467-79. PMID 24054925 DOI: 10.1016/j.beem.2013.05.016  1
2013 Metaxakis A, Partridge L. Dietary restriction extends lifespan in wild-derived populations of Drosophila melanogaster. Plos One. 8: e74681. PMID 24040317 DOI: 10.1371/journal.pone.0074681  1
2013 López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. 153: 1194-217. PMID 23746838 DOI: 10.1016/j.cell.2013.05.039  1
2013 Chouchani ET, Methner C, Nadtochiy SM, Logan A, Pell VR, Ding S, James AM, Cochemé HM, Reinhold J, Lilley KS, Partridge L, Fearnley IM, Robinson AJ, Hartley RC, Smith RA, et al. Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I. Nature Medicine. 19: 753-9. PMID 23708290 DOI: 10.1038/nm.3212  1
2013 Lee SF, Eyre-Walker YC, Rane RV, Reuter C, Vinti G, Rako L, Partridge L, Hoffmann AA. Polymorphism in the neurofibromin gene, Nf1, is associated with antagonistic selection on wing size and development time in Drosophila melanogaster. Molecular Ecology. 22: 2716-25. PMID 23506114 DOI: 10.1111/mec.12301  1
2013 Wredenberg A, Lagouge M, Bratic A, Metodiev MD, Spåhr H, Mourier A, Freyer C, Ruzzenente B, Tain L, Grönke S, Baggio F, Kukat C, Kremmer E, Wibom R, Polosa PL, ... ... Partridge L, et al. MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals. Plos Genetics. 9: e1003178. PMID 23300484 DOI: 10.1371/journal.pgen.1003178  1
2013 Gems D, Partridge L. Genetics of longevity in model organisms: debates and paradigm shifts. Annual Review of Physiology. 75: 621-44. PMID 23190075 DOI: 10.1146/annurev-physiol-030212-183712  1
2013 Slack C, Partridge L. Genes, pathways and metabolism in ageing Drug Discovery Today: Disease Models. 10: e87-e93. DOI: 10.1016/j.ddmod.2013.01.002  1
2012 Partridge L. Diet and healthy aging. The New England Journal of Medicine. 367: 2550-1. PMID 23268671 DOI: 10.1056/NEJMcibr1210447  1
2012 Papatheodorou I, Ziehm M, Wieser D, Alic N, Partridge L, Thornton JM. Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing. Plos One. 7: e50881. PMID 23251396 DOI: 10.1371/journal.pone.0050881  1
2012 Slack C, Foley A, Partridge L. Activation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in Drosophila. Plos One. 7: e47699. PMID 23077661 DOI: 10.1371/journal.pone.0047699  1
2012 Alic N, Hoddinott MP, Foley A, Slack C, Piper MD, Partridge L. Detrimental effects of RNAi: a cautionary note on its use in Drosophila ageing studies. Plos One. 7: e45367. PMID 23028964 DOI: 10.1371/journal.pone.0045367  1
2012 Gioti A, Wigby S, Wertheim B, Schuster E, Martinez P, Pennington CJ, Partridge L, Chapman T. Sex peptide of Drosophila melanogaster males is a global regulator of reproductive processes in females. Proceedings. Biological Sciences / the Royal Society. 279: 4423-32. PMID 22977156 DOI: 10.1098/rspb.2012.1634  1
2012 Niccoli T, Partridge L. Ageing as a risk factor for disease. Current Biology : Cb. 22: R741-52. PMID 22975005 DOI: 10.1016/j.cub.2012.07.024  1
2012 Neuhaus B, Niessen CM, Mesaros A, Withers DJ, Krieg T, Partridge L. Experimental analysis of risk factors for ulcerative dermatitis in mice. Experimental Dermatology. 21: 712-3. PMID 22897579 DOI: 10.1111/j.1600-0625.2012.01558.x  1
2012 Rogers I, Kerr F, Martinez P, Hardy J, Lovestone S, Partridge L. Ageing increases vulnerability to aβ42 toxicity in Drosophila. Plos One. 7: e40569. PMID 22808195 DOI: 10.1371/journal.pone.0040569  1
2012 Barzilai N, Guarente L, Kirkwood TB, Partridge L, Rando TA, Slagboom PE. The place of genetics in ageing research. Nature Reviews. Genetics. 13: 589-94. PMID 22777128 DOI: 10.1038/nrg3290  1
2012 Cochemé HM, Logan A, Prime TA, Abakumova I, Quin C, McQuaker SJ, Patel JV, Fearnley IM, James AM, Porteous CM, Smith RA, Hartley RC, Partridge L, Murphy MP. Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila. Nature Protocols. 7: 946-58. PMID 22517261 DOI: 10.1038/nprot.2012.035  1
2012 Chen Y, Lee SF, Blanc E, Reuter C, Wertheim B, Martinez-Diaz P, Hoffmann AA, Partridge L. Genome-wide transcription analysis of clinal genetic variation in Drosophila. Plos One. 7: e34620. PMID 22514645 DOI: 10.1371/journal.pone.0034620  1
2012 Aghdam SY, Eming SA, Willenborg S, Neuhaus B, Niessen CM, Partridge L, Krieg T, Bruning JC. Vascular endothelial insulin/IGF-1 signaling controls skin wound vascularization. Biochemical and Biophysical Research Communications. 421: 197-202. PMID 22503682 DOI: 10.1016/j.bbrc.2012.03.134  1
2012 Selman C, Partridge L. A double whammy for aging? Rapamycin extends lifespan and inhibits cancer in inbred female mice. Cell Cycle (Georgetown, Tex.). 11: 17-8. PMID 22186783 DOI: 10.4161/cc.11.1.18736  1
2012 Partridge L. Current developments at Philosophical Transactions of the Royal Society B. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 3. PMID 22106421 DOI: 10.1098/rstb.2011.0315  1
2011 Bratic A, Wredenberg A, Grönke S, Stewart JB, Mourier A, Ruzzenente B, Kukat C, Wibom R, Habermann B, Partridge L, Larsson NG. The bicoid stability factor controls polyadenylation and expression of specific mitochondrial mRNAs in Drosophila melanogaster. Plos Genetics. 7: e1002324. PMID 22022283 DOI: 10.1371/journal.pgen.1002324  1
2011 Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ, Vazquez-Manrique RP, Orfila AM, Ackerman D, Au C, Vinti G, ... ... Partridge L, et al. Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature. 477: 482-5. PMID 21938067 DOI: 10.1038/nature10296  1
2011 Alic N, Partridge L. Death and dessert: nutrient signalling pathways and ageing. Current Opinion in Cell Biology. 23: 738-43. PMID 21835601 DOI: 10.1016/j.ceb.2011.07.006  1
2011 Piper MD, Partridge L, Raubenheimer D, Simpson SJ. Dietary restriction and aging: a unifying perspective. Cell Metabolism. 14: 154-60. PMID 21803286 DOI: 10.1016/j.cmet.2011.06.013  1
2011 Alic N, Andrews TD, Giannakou ME, Papatheodorou I, Slack C, Hoddinott MP, Cochemé HM, Schuster EF, Thornton JM, Partridge L. Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling. Molecular Systems Biology. 7: 502. PMID 21694719 DOI: 10.1038/msb.2011.36  1
2011 Murphy MP, Holmgren A, Larsson NG, Halliwell B, Chang CJ, Kalyanaraman B, Rhee SG, Thornalley PJ, Partridge L, Gems D, Nyström T, Belousov V, Schumacker PT, Winterbourn CC. Unraveling the biological roles of reactive oxygen species. Cell Metabolism. 13: 361-6. PMID 21459321 DOI: 10.1016/j.cmet.2011.03.010  1
2011 Slack C, Giannakou ME, Foley A, Goss M, Partridge L. dFOXO-independent effects of reduced insulin-like signaling in Drosophila. Aging Cell. 10: 735-48. PMID 21443682 DOI: 10.1111/j.1474-9726.2011.00707.x  1
2011 Bjedov I, Partridge L. A longer and healthier life with TOR down-regulation: genetics and drugs. Biochemical Society Transactions. 39: 460-5. PMID 21428920 DOI: 10.1042/BST0390460  1
2011 Lee SF, Chen Y, Varan AK, Wee CW, Rako L, Axford JK, Good RT, Blacket MJ, Reuter C, Partridge L, Hoffmann AA. Molecular basis of adaptive shift in body size in Drosophila melanogaster: functional and sequence analyses of the Dca gene. Molecular Biology and Evolution. 28: 2393-402. PMID 21393605 DOI: 10.1093/molbev/msr064  1
2011 Cochemé HM, Quin C, McQuaker SJ, Cabreiro F, Logan A, Prime TA, Abakumova I, Patel JV, Fearnley IM, James AM, Porteous CM, Smith RA, Saeed S, Carré JE, Singer M, ... ... Partridge L, et al. Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix. Cell Metabolism. 13: 340-50. PMID 21356523 DOI: 10.1016/j.cmet.2011.02.003  1
2011 Augustin H, Allen MJ, Partridge L. Electrophysiological recordings from the giant fiber pathway of D. melanogaster. Journal of Visualized Experiments : Jove. PMID 21304452 DOI: 10.3791/2412  1
2011 Partridge L, Thornton J, Bates G. The new science of ageing. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 366: 6-8. PMID 21115524 DOI: 10.1098/rstb.2010.0298  1
2011 Alic N, Hoddinott MP, Vinti G, Partridge L. Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor. Aging Cell. 10: 137-47. PMID 21108726 DOI: 10.1111/j.1474-9726.2010.00653.x  1
2011 Partridge L. Some highlights of research on aging with invertebrates, 2010. Aging Cell. 10: 5-9. PMID 21078113 DOI: 10.1111/j.1474-9726.2010.00649.x  1
2011 Partridge L, Alic N, Bjedov I, Piper MD. Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network. Experimental Gerontology. 46: 376-81. PMID 20849947 DOI: 10.1016/j.exger.2010.09.003  1
2011 Wigby S, Slack C, Grönke S, Martinez P, Calboli FC, Chapman T, Partridge L. Insulin signalling regulates remating in female Drosophila. Proceedings. Biological Sciences / the Royal Society. 278: 424-31. PMID 20739318 DOI: 10.1098/rspb.2010.1390  1
2011 Kerr F, Augustin H, Piper MD, Gandy C, Allen MJ, Lovestone S, Partridge L. Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease. Neurobiology of Aging. 32: 1977-89. PMID 19969390 DOI: 10.1016/j.neurobiolaging.2009.10.015  1
2011 Partridge L. Comments from the new editor Philosophical Transactions of the Royal Society B: Biological Sciences. 366: 5. DOI: 10.1098/rstb.2010.0314  1
2010 Sofola O, Kerr F, Rogers I, Killick R, Augustin H, Gandy C, Allen MJ, Hardy J, Lovestone S, Partridge L. Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease. Plos Genetics. 6: e1001087. PMID 20824130 DOI: 10.1371/journal.pgen.1001087  1
2010 Fontana L, Partridge L, Longo VD. Extending healthy life span--from yeast to humans. Science (New York, N.Y.). 328: 321-6. PMID 20395504 DOI: 10.1126/science.1172539  1
2010 Jacobson J, Lambert AJ, Portero-Otín M, Pamplona R, Magwere T, Miwa S, Driege Y, Brand MD, Partridge L. Biomarkers of aging in Drosophila. Aging Cell. 9: 466-77. PMID 20367621 DOI: 10.1111/j.1474-9726.2010.00573.x  1
2010 Piper MD, Wong R, Grandison RC, Bass TM, Martinez PM, Partridge L. Water-independent effects of dietary restriction in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 107: E54-6; author reply . PMID 20363961 DOI: 10.1073/pnas.0914686107  1
2010 Slack C, Werz C, Wieser D, Alic N, Foley A, Stocker H, Withers DJ, Thornton JM, Hafen E, Partridge L. Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. Plos Genetics. 6: e1000881. PMID 20333234 DOI: 10.1371/journal.pgen.1000881  1
2010 Grönke S, Clarke DF, Broughton S, Andrews TD, Partridge L. Molecular evolution and functional characterization of Drosophila insulin-like peptides. Plos Genetics. 6: e1000857. PMID 20195512 DOI: 10.1371/journal.pgen.1000857  1
2010 Broughton SJ, Slack C, Alic N, Metaxakis A, Bass TM, Driege Y, Partridge L. DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition. Aging Cell. 9: 336-46. PMID 20156206 DOI: 10.1111/j.1474-9726.2010.00558.x  1
2010 Bjedov I, Toivonen JM, Kerr F, Slack C, Jacobson J, Foley A, Partridge L. Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster. Cell Metabolism. 11: 35-46. PMID 20074526 DOI: 10.1016/j.cmet.2009.11.010  1
2010 Partridge L. The new biology of ageing. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 365: 147-54. PMID 20008392 DOI: 10.1098/rstb.2009.0222  1
2010 Fontana L, Partridge L, Longo VD. Dietary restriction: Theory fails to satiate - Response Science. 329: 1015. DOI: 10.1126/science.329.5995.1015  1
2010 Fontana L, Partridge L. Dietary restriction: Standing up for sirtuins - Response Science. 329: 1013.  1
2009 Slaidina M, Delanoue R, Gronke S, Partridge L, Léopold P. A Drosophila insulin-like peptide promotes growth during nonfeeding states. Developmental Cell. 17: 874-84. PMID 20059956 DOI: 10.1016/j.devcel.2009.10.009  1
2009 Grandison RC, Piper MD, Partridge L. Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila. Nature. 462: 1061-4. PMID 19956092 DOI: 10.1038/nature08619  1
2009 Selman C, Tullet JM, Wieser D, Irvine E, Lingard SJ, Choudhury AI, Claret M, Al-Qassab H, Carmignac D, Ramadani F, Woods A, Robinson IC, Schuster E, Batterham RL, Kozma SC, ... ... Partridge L, et al. Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. Science (New York, N.Y.). 326: 140-4. PMID 19797661 DOI: 10.1126/science.1177221  0.48
2009 Ikeya T, Broughton S, Alic N, Grandison R, Partridge L. The endosymbiont Wolbachia increases insulin/IGF-like signalling in Drosophila. Proceedings. Biological Sciences / the Royal Society. 276: 3799-807. PMID 19692410 DOI: 10.1098/rspb.2009.0778  1
2009 Iqbal A, Piper M, Faragher RG, Naughton DP, Partridge L, Ostler EL. Chemical changes in aging Drosophila melanogaster. Age (Dordrecht, Netherlands). 31: 343-51. PMID 19585275 DOI: 10.1007/s11357-009-9105-4  1
2009 Partridge L. Some highlights of research on aging with invertebrates, 2009. Aging Cell. 8: 509-13. PMID 19558590 DOI: 10.1111/j.1474-9726.2009.00498.x  1
2009 Wong R, Piper MD, Wertheim B, Partridge L. Quantification of food intake in Drosophila. Plos One. 4: e6063. PMID 19557170 DOI: 10.1371/journal.pone.0006063  1
2009 Toivonen JM, Gems D, Partridge L. Longevity of Indy mutant Drosophila not attributable to Indy mutation. Proceedings of the National Academy of Sciences of the United States of America. 106: E53; author reply E5. PMID 19435842 DOI: 10.1073/pnas.0902462106  1
2009 Humphrey DM, Toivonen JM, Giannakou M, Partridge L, Brand MD. Expression of human uncoupling protein-3 in Drosophila insulin-producing cells increases insulin-like peptide (DILP) levels and shortens lifespan. Experimental Gerontology. 44: 316-27. PMID 19385039 DOI: 10.1016/j.exger.2009.02.001  1
2009 Broughton S, Partridge L. Insulin/IGF-like signalling, the central nervous system and aging. The Biochemical Journal. 418: 1-12. PMID 19159343 DOI: 10.1042/BJ20082102  0.52
2009 Grandison RC, Wong R, Bass TM, Partridge L, Piper MD. Effect of a standardised dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster. Plos One. 4: e4067. PMID 19119322 DOI: 10.1371/journal.pone.0004067  1
2009 Toivonen JM, Partridge L. Endocrine regulation of aging and reproduction in Drosophila. Molecular and Cellular Endocrinology. 299: 39-50. PMID 18682271 DOI: 10.1016/j.mce.2008.07.005  1
2008 Broughton S, Alic N, Slack C, Bass T, Ikeya T, Vinti G, Tommasi AM, Driege Y, Hafen E, Partridge L. Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs. Plos One. 3: e3721. PMID 19005568 DOI: 10.1371/journal.pone.0003721  1
2008 Partridge L. Some highlights of research on aging with invertebrates, 2008. Aging Cell. 7: 605-8. PMID 18631320 DOI: 10.1111/j.1474-9726.2008.00415.x  1
2008 Alic N, Partridge L. Stage debut for the elusive Drosophila insulin-like growth factor binding protein. Journal of Biology. 7: 18. PMID 18620552 DOI: 10.1186/jbiol79  1
2008 Butler RN, Miller RA, Perry D, Carnes BA, Williams TF, Cassel C, Brody J, Bernard MA, Partridge L, Kirkwood T, Martin GM, Olshansky SJ. New model of health promotion and disease prevention for the 21st century. Bmj (Clinical Research Ed.). 337: a399. PMID 18614506 DOI: 10.1136/bmj.a399  0.52
2008 Selman C, Lingard S, Gems D, Partridge L, Withers DJ. Comment on "Brain IRS2 signaling coordinates life span and nutrient homeostasis". Science (New York, N.Y.). 320: 1012; author reply 1. PMID 18497277 DOI: 10.1126/science.1152366  0.52
2008 Barnes AI, Wigby S, Boone JM, Partridge L, Chapman T. Feeding, fecundity and lifespan in female Drosophila melanogaster. Proceedings. Biological Sciences / the Royal Society. 275: 1675-83. PMID 18430646 DOI: 10.1098/rspb.2008.0139  1
2008 Partridge L, Brüning JC. Forkhead transcription factors and ageing Oncogene. 27: 2351-2363. PMID 18391977 DOI: 10.1038/onc.2008.28  0.52
2008 Murphy MP, Partridge L. Toward a control theory analysis of aging. Annual Review of Biochemistry. 77: 777-98. PMID 18318658 DOI: 10.1146/annurev.biochem.77.070606.101605  0.52
2008 Gems D, Partridge L. Stress-response hormesis and aging: "that which does not kill us makes us stronger". Cell Metabolism. 7: 200-3. PMID 18316025 DOI: 10.1016/j.cmet.2008.01.001  0.52
2008 Giannakou ME, Goss M, Partridge L. Role of dFOXO in lifespan extension by dietary restriction in Drosophila melanogaster: not required, but its activity modulates the response. Aging Cell. 7: 187-98. PMID 18241326 DOI: 10.1111/j.1474-9726.2007.00362.x  1
2008 Piper MD, Selman C, McElwee JJ, Partridge L. Separating cause from effect: how does insulin/IGF signalling control lifespan in worms, flies and mice? Journal of Internal Medicine. 263: 179-91. PMID 18226095 DOI: 10.1111/j.1365-2796.2007.01906.x  1
2008 Selman C, Lingard S, Choudhury AI, Batterham RL, Claret M, Clements M, Ramadani F, Okkenhaug K, Schuster E, Blanc E, Piper MD, Al-Qassab H, Speakman JR, Carmignac D, Robinson IC, ... ... Partridge L, et al. Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 807-18. PMID 17928362 DOI: 10.1096/fj.07-9261com  1
2008 Milton CC, Partridge L. Brief carbon dioxide exposure blocks heat hardening but not cold acclimation in Drosophila melanogaster. Journal of Insect Physiology. 54: 32-40. PMID 17884085 DOI: 10.1016/j.jinsphys.2007.08.001  1
2008 Wong R, Piper MDW, Blanc E, Partridge L. Reply to "Pitfalls of measuring feeding rate in the fruit fly Drosophila melanogaster" [5] Nature Methods. 5: 215. DOI: 10.1038/nmeth0308-215  1
2007 Pletcher SD, Kabil H, Partridge L. Chemical Complexity and the Genetics of Aging. Annual Review of Ecology, Evolution, and Systematics. 38: 299-326. PMID 25685107 DOI: 10.1146/annurev.ecolsys.38.091206.095634  0.52
2007 Partridge L, Gems D. Benchmarks for ageing studies. Nature. 450: 165-7. PMID 17994065 DOI: 10.1038/450165a  0.52
2007 Bass TM, Grandison RC, Wong R, Martinez P, Partridge L, Piper MD. Optimization of dietary restriction protocols in Drosophila. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 62: 1071-81. PMID 17921418  1
2007 Bass TM, Weinkove D, Houthoofd K, Gems D, Partridge L. Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans. Mechanisms of Ageing and Development. 128: 546-52. PMID 17875315 DOI: 10.1016/j.mad.2007.07.007  1
2007 Alic N, Partridge L. Antagonizing Methuselah to extend life span. Genome Biology. 8: 222. PMID 17764591 DOI: 10.1186/gb-2007-8-8-222  1
2007 Partridge L. Some highlights of research on aging with invertebrates, 2006-2007 Aging Cell. 6: 595-598. PMID 17725687 DOI: 10.1111/j.1474-9726.2007.00334.x  1
2007 McElwee JJ, Schuster E, Blanc E, Piper MD, Thomas JH, Patel DS, Selman C, Withers DJ, Thornton JM, Partridge L, Gems D. Evolutionary conservation of regulated longevity assurance mechanisms. Genome Biology. 8: R132. PMID 17612391 DOI: 10.1186/gb-2007-8-7-r132  1
2007 Kennington WJ, Hoffmann AA, Partridge L. Mapping regions within cosmopolitan inversion In(3R)Payne associated with natural variation in body size in Drosophila melanogaster. Genetics. 177: 549-56. PMID 17603103 DOI: 10.1534/genetics.107.074336  1
2007 Schuster EF, Blanc E, Partridge L, Thornton JM. Estimation and correction of non-specific binding in a large-scale spike-in experiment. Genome Biology. 8: R126. PMID 17594493 DOI: 10.1186/gb-2007-8-6-r126  1
2007 Schuster EF, Blanc E, Partridge L, Thornton JM. Correcting for sequence biases in present/absent calls. Genome Biology. 8: R125. PMID 17594492 DOI: 10.1186/gb-2007-8-6-r125  1
2007 Toivonen JM, Walker GA, Martinez-Diaz P, Bjedov I, Driege Y, Jacobs HT, Gems D, Partridge L. No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects. Plos Genetics. 3: e95. PMID 17571923 DOI: 10.1371/journal.pgen.0030095  1
2007 Giannakou ME, Goss M, Jacobson J, Vinti G, Leevers SJ, Partridge L. Dynamics of the action of dFOXO on adult mortality in Drosophila Aging Cell. 6: 429-438. PMID 17465980 DOI: 10.1111/j.1474-9726.2007.00290.x  1
2007 Piper MD, Partridge L. Dietary restriction in Drosophila: delayed aging or experimental artefact? Plos Genetics. 3: e57. PMID 17465680 DOI: 10.1371/journal.pgen.0030057  1
2007 Giannakou ME, Partridge L. Role of insulin-like signalling in Drosophila lifespan Trends in Biochemical Sciences. 32: 180-188. PMID 17412594 DOI: 10.1016/j.tibs.2007.02.007  1
2007 Piper M, Mair W, Partridge L. Comment by Matthew Piper, William Mair, Linda Partridge on Min, K.J., Flatt, T., Kulaots, I., Tatar, M. (2006) "Counting calories in Drosophila dietary restriction" Exp. Gerontology, doi:10.1016/j.exger.2006.10.009 Experimental Gerontology. 42: 253-255. PMID 17317064 DOI: 10.1016/j.exger.2007.01.002  1
2007 Barnes AI, Boone JM, Partridge L, Chapman T. A functioning ovary is not required for sex peptide to reduce receptivity to mating in D. melanogaster. Journal of Insect Physiology. 53: 343-8. PMID 17303161 DOI: 10.1016/j.jinsphys.2006.12.008  1
2007 Kabil H, Partridge L, Harshman LG. Superoxide dismutase activities in long-lived Drosophila melanogaster females: Chico1 genotypes and dietary dilution Biogerontology. 8: 201-208. PMID 17103233 DOI: 10.1007/s10522-006-9065-3  1
2007 Toivonen JM, Walker GA, Martinez-Diaz P, Bjedov I, Driege Y, Jacobs HT, Gems D, Partridge L. No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects Plos Genetics. 3: 0973-0983. DOI: 10.1371/journal.pgen.0030095  1
2006 Selman C, Kerrison ND, Cooray A, Piper MD, Lingard SJ, Barton RH, Schuster EF, Blanc E, Gems D, Nicholson JK, Thornton JM, Partridge L, Withers DJ. Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice. Physiological Genomics. 27: 187-200. PMID 16882887 DOI: 10.1152/physiolgenomics.00084.2006  1
2006 Partridge L, Gems D. Beyond the evolutionary theory of ageing, from functional genomics to evo-gero Trends in Ecology and Evolution. 21: 334-340. PMID 16769434 DOI: 10.1016/j.tree.2006.02.008  1
2006 Barnes AI, Boone JM, Jacobson J, Partridge L, Chapman T. No extension of lifespan by ablation of germ line in Drosophila. Proceedings. Biological Sciences / the Royal Society. 273: 939-47. PMID 16627279 DOI: 10.1098/rspb.2005.3388  1
2006 Magwere T, Pamplona R, Miwa S, Martinez-Diaz P, Portero-Otin M, Brand MD, Partridge L. Flight activity, mortality rates, and lipoxidative damage in Drosophila Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 61: 136-145. PMID 16510857  1
2006 Magwere T, Goodall S, Skepper J, Mair W, Brand MD, Partridge L. The effect of dietary restriction on mitochondrial protein density and flight muscle mitochondrial morphology in Drosophila Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 61: 36-47. PMID 16456193  1
2006 Magwere T, West M, Riyahi K, Murphy MP, Smith RA, Partridge L. The effects of exogenous antioxidants on lifespan and oxidative stress resistance in Drosophila melanogaster. Mechanisms of Ageing and Development. 127: 356-70. PMID 16442589 DOI: 10.1016/j.mad.2005.12.009  1
2006 Kennington WJ, Partridge L, Hoffmann AA. Patterns of diversity and linkage disequilibrium within the cosmopolitan inversion In(3R)Payne in Drosophila melanogaster are indicative of coadaptation. Genetics. 172: 1655-63. PMID 16322502 DOI: 10.1534/genetics.105.053173  1
2006 Partridge L. Of worms, mice & men: Altering rates of aging Daedalus. 135: 40-47. DOI: 10.1162/001152606775321013  1
2006 Pizzari T, Birkhead TR, Blows MW, Brooks R, Buchanan KL, Clutton-Brock TH, Harvey PH, Hosken DJ, Jennions MD, Kokko H, Kotiaho JS, Lessells CM, Macias-García C, Moore AJ, Parker GA, ... Partridge L, et al. Debating sexual selection and mating strategies [3] Science. 312: 690.  0.52
2005 Wertheim B, Kraaijeveld AR, Schuster E, Blanc E, Hopkins M, Pletcher SD, Strand MR, Partridge L, Godfray HC. Genome-wide gene expression in response to parasitoid attack in Drosophila. Genome Biology. 6: R94. PMID 16277749 DOI: 10.1186/gb-2005-6-11-r94  1
2005 Piper MDW, Skorupa D, Partridge L. Diet, metabolism and lifespan in Drosophila Experimental Gerontology. 40: 857-862. PMID 16137851 DOI: 10.1016/j.exger.2005.06.013  1
2005 Sharma P, Asztalos Z, Ayyub C, de Bruyne M, Dornan AJ, Gomez-Hernandez A, Keane J, Killeen J, Kramer S, Madhavan M, Roe H, Sherkhane PD, Siddiqi K, Silva E, Carlson JR, ... ... Partridge L, et al. Isogenic autosomes to be applied in optimal screening for novel mutants with viable phenotypes in Drosophila melanogaster. Journal of Neurogenetics. 19: 57-85. PMID 16024440 DOI: 10.1080/01677060591007155  1
2005 Mair W, Piper MD, Partridge L. Calories do not explain extension of life span by dietary restriction in Drosophila. Plos Biology. 3: e223. PMID 16000018 DOI: 10.1371/journal.pbio.0030223  0.84
2005 Piper MDW, Mair W, Partridge L. Counting the calories: The role of specific nutrients in extension of life span by food restriction Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 60: 549-555. PMID 15972601  1
2005 Partridge L, Piper MD, Mair W. Dietary restriction in Drosophila. Mechanisms of Ageing and Development. 126: 938-50. PMID 15935441 DOI: 10.1016/j.mad.2005.03.023  0.84
2005 Richard DS, Rybczynski R, Wilson TG, Wang Y, Wayne ML, Zhou Y, Partridge L, Harshman LG. Insulin signaling is necessary for vitellogenesis in Drosophila melanogaster independent of the roles of juvenile hormone and ecdysteroids: female sterility of the chico1 insulin signaling mutation is autonomous to the ovary. Journal of Insect Physiology. 51: 455-64. PMID 15890189 DOI: 10.1016/j.jinsphys.2004.12.013  1
2005 Partridge L, Gems D, Withers DJ. Sex and death: What is the connection? Cell. 120: 461-472. PMID 15734679 DOI: 10.1016/j.cell.2005.01.026  1
2005 Broughton SJ, Piper MD, Ikeya T, Bass TM, Jacobson J, Driege Y, Martinez P, Hafen E, Withers DJ, Leevers SJ, Partridge L. Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands. Proceedings of the National Academy of Sciences of the United States of America. 102: 3105-10. PMID 15708981 DOI: 10.1073/pnas.0405775102  0.84
2005 Partridge L, Pletcher SD, Mair W. Dietary restriction, mortality trajectories, risk and damage. Mechanisms of Ageing and Development. 126: 35-41. PMID 15610760 DOI: 10.1016/j.mad.2004.09.017  1
2005 Gardner MP, Fowler K, Barton NH, Partridge L. Genetic variation for total fitness in Drosophila melanogaster: complex yet replicable patterns. Genetics. 169: 1553-71. PMID 15545656 DOI: 10.1534/genetics.104.032367  1
2005 Mair W, Piper MDW, Partridge L. Calories do not explain extension of life span by dietary restriction in Drosophila Plos Biology. 3: 1305-1311. DOI: 10.1371/journal.pbio.0030223  1
2005 Partridge L, Brand MD. Special issue on dietary restriction: Dietary restriction, longevity and ageing - The current state of our knowledge and ignorance Mechanisms of Ageing and Development. 126: 911-912. DOI: 10.1016/j.mad.2005.04.003  1
2005 Piper MDW, Selman C, McElwee JJ, Partridge L. Models of insulin signalling and longevity Drug Discovery Today: Disease Models. 2: 249-256. DOI: 10.1016/j.ddmod.2005.11.001  1
2004 Eyre TA, Partridge L, Thornton JM. Computational analysis of alpha-helical membrane protein structure: implications for the prediction of 3D structural models. Protein Engineering, Design & Selection : Peds. 17: 613-24. PMID 15388845 DOI: 10.1093/protein/gzh072  1
2004 Giannakou ME, Partridge L. The interaction between FOXO and SIRT1: Tipping the balance towards survival Trends in Cell Biology. 14: 408-412. PMID 15308206 DOI: 10.1016/j.tcb.2004.07.006  1
2004 Hulbert AJ, Clancy DJ, Mair W, Braeckman BP, Gems D, Partridge L. Metabolic rate is not reduced by dietary-restriction or by lowered insulin/IGF-1 signalling and is not correlated with individual lifespan in Drosophila melanogaster. Experimental Gerontology. 39: 1137-43. PMID 15288688 DOI: 10.1016/j.exger.2004.04.006  1
2004 Miwa S, Riyahi K, Partridge L, Brand MD. Lack of correlation between mitochondrial reactive oxygen species production and life span in Drosophila Annals of the New York Academy of Sciences. 1019: 388-391. PMID 15247051 DOI: 10.1196/annals.1297.069  1
2004 Mair W, Sgrò CM, Johnson AP, Chapman T, Partridge L. Lifespan extension by dietary restriction in female Drosophila melanogaster is not caused by a reduction in vitellogenesis or ovarian activity. Experimental Gerontology. 39: 1011-9. PMID 15236760 DOI: 10.1016/j.exger.2004.03.018  1
2004 Giannakou ME, Goss M, Jünger MA, Hafen E, Leevers SJ, Partridge L. Long-lived Drosophila with overexpressed dFOXO in adult fat body. Science (New York, N.Y.). 305: 361. PMID 15192154 DOI: 10.1126/science.1098219  0.52
2004 Magwere T, Chapman T, Partridge L. Sex differences in the effect of dietary restriction on life span and mortality rates in female and male Drosophila melanogaster. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 59: 3-9. PMID 14718480  1
2004 Rauser CL, Mueller LD, Rose MR, Mair W, Goymer P, Pletcher SD, Partridge L. Dietary Restriction in Drosophilla [2] (multiple letters) Science. 303: 1610-1612.  1
2003 Calboli FCF, Kennington WJ, Partridge L. QTL mapping reveals a striking coincidence in the positions of genomic regions associated with adaptive variation in body size in parallel clines of Drosophila melanogaster on different continents Evolution. 57: 2653-2658. PMID 14686541  1
2003 Hoffmann AA, Scott M, Partridge L, Hallas R. Overwintering in Drosophila melanogaster: Outdoor field cage experiments on clinal and laboratory selected populations help to elucidate traits under selection Journal of Evolutionary Biology. 16: 614-623. PMID 14632225 DOI: 10.1046/j.1420-9101.2003.00561.x  1
2003 Kennington WJ, Gockel J, Partridge L. Testing for Asymmetrical Gene Flow in a Drosophila melanogaster Body-Size Cline Genetics. 165: 667-673. PMID 14573478  1
2003 Miwa S, St-Pierre J, Partridge L, Brand MD. Superoxide and hydrogen peroxide production by Drosophila mitochondria Free Radical Biology and Medicine. 35: 938-948. PMID 14556858 DOI: 10.1016/S0891-5849(03)00464-7  1
2003 Mair W, Goymer P, Pletcher SD, Partridge L. Demography of dietary restriction and death in Drosophila. Science (New York, N.Y.). 301: 1731-3. PMID 14500985 DOI: 10.1126/science.1086016  1
2003 Chapman T, Bangham J, Vinti G, Seifried B, Lung O, Wolfner MF, Smith HK, Partridge L. The sex peptide of Drosophila melanogaster: female post-mating responses analyzed by using RNA interference. Proceedings of the National Academy of Sciences of the United States of America. 100: 9923-8. PMID 12893873 DOI: 10.1073/pnas.1631635100  1
2003 Kennington WJ, Killeen JR, Goldstein DB, Partridge L. Rapid laboratory evolution of adult wing area in Drosophila melanogaster in response to humidity Evolution. 57: 932-936. PMID 12778562  1
2003 Calboli FCF, Gilchrist GW, Partridge L. Different cell size and cell number contribution in two newly established and one ancient body size cline of Drosophila subobscura Evolution. 57: 566-573. PMID 12703946  1
2003 Bangham J, Chapman T, Smith HK, Partridge L. Influence of female reproductive anatomy on the outcome of sperm competition in Drosophila melanogaster. Proceedings. Biological Sciences / the Royal Society. 270: 523-30. PMID 12641908 DOI: 10.1098/rspb.2002.2237  1
2003 Barnes AI, Partridge L. Costing reproduction Animal Behaviour. 66: 199-204. DOI: 10.1006/anbe.2003.2122  1
2002 Gems D, Pletcher S, Partridge L. Interpreting interactions between treatments that slow aging Aging Cell. 1: 1-9. PMID 12882347  1
2002 Carey JR, Liedo P, Harshman L, Zhang Y, Müller HG, Partridge L, Wang JL. Life history response of Mediterranean fruit flies to dietary restriction. Aging Cell. 1: 140-8. PMID 12882344  1
2002 Partridge L, Gems D. A lethal side-effect Nature. 418: 921. PMID 12198525 DOI: 10.1038/418921a  1
2002 Partridge L, Gems D. The evolution of longevity Current Biology : Cb. 12: R544-546. PMID 12194832  1
2002 Gockel J, Robinson SJW, Kennington WJ, Goldstein DB, Partridge L. Quantitative genetic analysis of natural variation in body size in Drosophila melanogaster Heredity. 89: 145-153. PMID 12136418 DOI: 10.1038/sj.hdy.6800121  1
2002 Bartke A, Wright JC, Mattison JA, Ingram DK, Miller RA, Roth GS. Dietary restriction and life-span. Science (New York, N.Y.). 296: 2141-2; author reply. PMID 12094784 DOI: 10.1126/science.296.5576.2141  1
2002 Pletcher SD, Macdonald SJ, Marguerie R, Certa U, Stearns SC, Goldstein DB, Partridge L. Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster. Current Biology : Cb. 12: 712-23. PMID 12007414 DOI: 10.1016/S0960-9822(02)00808-4  1
2002 Partridge L, Gems D. Mechanisms of ageing: Public or private? Nature Reviews Genetics. 3: 165-175. PMID 11972154 DOI: 10.1038/nrg753  1
2002 Clancy DJ, Gems D, Hafen E, Leevers SJ, Partridge L. Dietary restriction in long-lived dwarf flies. Science (New York, N.Y.). 296: 319. PMID 11951037 DOI: 10.1126/science.1069366  0.48
2002 Carey JR, Liedo P, Harshman L, Zhang Y, Müller HG, Partridge L, Wang JL. A mortality cost of virginity at older ages in female Mediterranean fruit flies. Experimental Gerontology. 37: 507-12. PMID 11830353 DOI: 10.1016/S0531-5565(01)00230-3  1
2002 Carey JR, Liedo P, Harshman L, Liu X, Müller HG, Partridge L, Wang JL. Food pulses increase longevity and induce cyclical egg production in Mediterranean fruit flies Functional Ecology. 16: 313-325. DOI: 10.1046/j.1365-2435.2002.00633.x  1
2002 Azevedo RBR, French V, Partridge L. Temperature modulates epidermal cell size in Drosophila melanogaster Journal of Insect Physiology. 48: 231-237. DOI: 10.1016/S0022-1910(01)00168-8  1
2002 Bangham J, Chapman T, Partridge L. Effects of body size, accessory gland and testis size on pre- and postcopulatory success in Drosophila melanogaster Animal Behaviour. 64: 915-921. DOI: 10.1006/anbe.2002.1976  1
2001 Sgrò CM, Partridge L. Laboratory adaptation of life history in Drosophila. The American Naturalist. 158: 657-8. PMID 18707359 DOI: 10.1086/323592  1
2001 Kennington WJ, Gilchrist AS, Goldstein DB, Partridge L. The genetic bases of divergence in desiccation and starvation resistance among tropical and temperate populations of Drosophila melanogaster. Heredity. 87: 363-72. PMID 11737283 DOI: 10.1046/j.1365-2540.2001.00925.x  1
2001 Gardner M, Fowler K, Partridge L, Barton N. Genetic variation for preadult viability in Drosophila melanogaster Evolution. 55: 1609-1620. PMID 11580020  1
2001 Chapman T, Herndon LA, Heifetz Y, Partridge L, Wolfner MF. The Acp26Aa seminal fluid protein is a modulator of early egg hatchability in Drosophila melanogaster. Proceedings. Biological Sciences / the Royal Society. 268: 1647-54. PMID 11506676 DOI: 10.1098/rspb.2001.1684  1
2001 Gilchrist AS, Partridge L. The contrasting genetic architecture of wing size and shape in Drosophila melanogaster. Heredity. 86: 144-52. PMID 11380659  1
2001 Clancy DJ, Gems D, Harshman LG, Oldham S, Stocker H, Hafen E, Leevers SJ, Partridge L. Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science (New York, N.Y.). 292: 104-6. PMID 11292874 DOI: 10.1126/science.1057991  1
2000 Sgrò CM, Geddes G, Fowler K, Partridge L. Selection on age at reproduction in Drosophila melanogaster: female mating frequency as a correlated response. Evolution; International Journal of Organic Evolution. 54: 2152-5. PMID 11209790  1
2000 Chapman T, Neubaum DM, Wolfner MF, Partridge L. The role of male accessory gland protein Acp36DE in sperm competition in Drosophila melanogaster. Proceedings. Biological Sciences / the Royal Society. 267: 1097-105. PMID 10885514 DOI: 10.1098/rspb.2000.1114  1
1999 Miyatake T, Chapman T, Partridge L. Mating-induced inhibition of remating in female Mediterranean fruit flies Ceratitis capitata. Journal of Insect Physiology. 45: 1021-1028. PMID 12770277 DOI: 10.1016/S0022-1910(99)00083-9  1
1999 Sgrò CM, Partridge L. A delayed wave of death from reproduction in Drosophila. Science (New York, N.Y.). 286: 2521-4. PMID 10617470  0.88
1998 James AC, Partridge L. Geographic variation in competitive ability in Drosophila melanogaster. The American Naturalist. 151: 530-7. PMID 18811374 DOI: 10.1086/286138  1
1998 Sgrò CM, Chapman T, Partridge L. Sex-specific selection on time to remate in Drosophila melanogaster. Animal Behaviour. 56: 1267-1278. PMID 9819344 DOI: 10.1006/anbe.1998.0900  1
1998 Chapman T, Miyatake T, Smith HK, Partridge L. Interactions of mating, egg production and death rates in females of the Mediterranean fruit fly, Ceratitis capitata. Proceedings. Biological Sciences / the Royal Society. 265: 1879-94. PMID 9802244 DOI: 10.1098/rspb.1998.0516  1
1998 Partridge L, Sgrò CM. Behavioural genetics: molecular genetics meets feeding ecology. Current Biology : Cb. 8: R23-4. PMID 9427617  0.88
1997 Wolfner MF, Partridge L, Lewin S, Kalb JM, Chapman T, Herndon LA. Mating and hormonal triggers regulate accessory gland gene expression in male Drosophila. Journal of Insect Physiology. 43: 1117-1123. PMID 12770484 DOI: 10.1016/S0022-1910(97)00062-0  1
1996 Chapman T, Partridge L. Female fitness in Drosophila melanogaster: an interaction between the effect of nutrition and of encounter rate with males. Proceedings. Biological Sciences / the Royal Society. 263: 755-9. PMID 8763795 DOI: 10.1098/rspb.1996.0113  1
1996 Chapman T, Partridge L. Sexual conflict as fuel for evolution. Nature. 381: 189-90. PMID 8622753 DOI: 10.1038/381189a0  1
1995 Chapman T, Liddle LF, Kalb JM, Wolfner MF, Partridge L. Cost of mating in Drosophila melanogaster females is mediated by male accessory gland products. Nature. 373: 241-4. PMID 7816137 DOI: 10.1038/373241a0  1
1993 Chapman T, Hutchings J, Partridge L. No reduction in the cost of mating for Drosophila melanogaster females mating with spermless males. Proceedings. Biological Sciences / the Royal Society. 253: 211-7. PMID 8234360 DOI: 10.1098/rspb.1993.0105  1
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