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Mark L. Siegal, Ph.D. - Publications

Affiliations: 
2005- Biology New York University, New York, NY, United States 
Area:
evolution, sex
Website:
https://wp.nyu.edu/siegal/

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Sartori FMO, Buzby C, Plavskin Y, Siegal ML. High-Throughput Live Imaging of Microcolonies to Measure Heterogeneity in Growth and Gene Expression. Journal of Visualized Experiments : Jove. PMID 33938878 DOI: 10.3791/62038  0.96
2020 Geiler-Samerotte KA, Li S, Lazaris C, Taylor A, Ziv N, Ramjeawan C, Paaby AB, Siegal ML. Extent and context dependence of pleiotropy revealed by high-throughput single-cell phenotyping. Plos Biology. 18: e3000836. PMID 32804946 DOI: 10.1371/journal.pbio.3000836  0.4
2019 Conley D, Siegal ML, Domingue BW, Harris KM, McQueen MB, Boardman JD. Author Correction: Testing the key assumption of heritability estimates based on genome-wide genetic relatedness. Journal of Human Genetics. PMID 30940889 DOI: 10.1038/S10038-019-0593-5  1
2018 Geiler-Samerotte K, Sartori FMO, Siegal ML. Decanalizing thinking on genetic canalization. Seminars in Cell & Developmental Biology. PMID 29751086 DOI: 10.1016/J.Semcdb.2018.05.008  0.96
2018 Conley D, Johnson R, Domingue B, Dawes C, Boardman J, Siegal ML. Correction: A sibling method for identifying vQTLs. Plos One. 13: e0196881. PMID 29715327 DOI: 10.1371/Journal.Pone.0196881  1
2018 Conley D, Johnson R, Domingue B, Dawes C, Boardman J, Siegal M. A sibling method for identifying vQTLs. Plos One. 13: e0194541. PMID 29617452 DOI: 10.1371/Journal.Pone.0194541  1
2017 Assaf ZJ, Park J, Tilk S, Siegal ML, Petrov D. Deep sequencing of natural and experimental populations of Drosophila melanogaster reveals biases in the spectrum of new mutations. Genome Research. PMID 29079675 DOI: 10.1101/gr.219956.116  0.56
2016 Wayne G, Graves A, Hassabis D, Saha S, Weber CA, Hyman AA, Juelicher F, Stroud DA, Ryan MT, Potvin-Trottier L, Paulsson J, Geiler-Samerotte KA, Siegal ML, Uhlen M, Edfors F, et al. Principles of Systems Biology, No. 11 Cell Systems. 3: 406-410. PMID 27883884 DOI: 10.1016/J.Cels.2016.11.010  0.4
2016 Geiler-Samerotte KA, Zhu YO, Goulet BE, Hall DW, Siegal ML. Selection Transforms the Landscape of Genetic Variation Interacting with Hsp90. Plos Biology. 14: e2000465. PMID 27768682 DOI: 10.1371/Journal.Pbio.2000465  0.44
2015 Rauscher E, Conley D, Siegal ML. Sibling genes as environment: Sibling dopamine genotypes and adolescent health support frequency dependent selection. Social Science Research. 54: 209-20. PMID 26463544 DOI: 10.1016/J.Ssresearch.2015.08.002  1
2015 Siegal ML. Shifting sugars and shifting paradigms. Plos Biology. 13: e1002068. PMID 25688600 DOI: 10.1371/journal.pbio.1002068  1
2015 Bauer CR, Li S, Siegal ML. Essential gene disruptions reveal complex relationships between phenotypic robustness, pleiotropy, and fitness. Molecular Systems Biology. 11: 773. PMID 25609648 DOI: 10.15252/msb.20145264  1
2014 Siegal ML, Leu JY. On the Nature and Evolutionary Impact of Phenotypic Robustness Mechanisms. Annual Review of Ecology, Evolution, and Systematics. 45: 496-517. PMID 26034410 DOI: 10.1146/annurev-ecolsys-120213-091705  1
2014 Zhu YO, Siegal ML, Hall DW, Petrov DA. Reply to Chen and Zhang: On interpreting genome-wide trends from yeast mutation accumulation data. Proceedings of the National Academy of Sciences of the United States of America. 111: E4063. PMID 25217565 DOI: 10.1073/Pnas.1413861111  1
2014 Arbeitman MN, Kopp A, L Siegal M, Van Doren M. The genetics of sex: exploring differences. Genetics. 197: 527-9. PMID 24939993 DOI: 10.1534/Genetics.114.165456  1
2014 Arbeitman MN, Kopp A, Siegal ML, Van Doren M. The genetics of sex: exploring differences. G3 (Bethesda, Md.). 4: 979-81. PMID 24939183 DOI: 10.1534/G3.114.011692  0.6
2014 Zhu YO, Siegal ML, Hall DW, Petrov DA. Precise estimates of mutation rate and spectrum in yeast. Proceedings of the National Academy of Sciences of the United States of America. 111: E2310-8. PMID 24847077 DOI: 10.1073/Pnas.1323011111  1
2014 Conley D, Siegal ML, Domingue BW, Mullan Harris K, McQueen MB, Boardman JD. Testing the key assumption of heritability estimates based on genome-wide genetic relatedness. Journal of Human Genetics. 59: 342-5. PMID 24599117 DOI: 10.1038/Jhg.2014.14  1
2013 Richardson JB, Uppendahl LD, Traficante MK, Levy SF, Siegal ML. Histone variant HTZ1 shows extensive epistasis with, but does not increase robustness to, new mutations. Plos Genetics. 9: e1003733. PMID 23990806 DOI: 10.1371/Journal.Pgen.1003733  1
2013 Ziv N, Siegal ML, Gresham D. Genetic and nongenetic determinants of cell growth variation assessed by high-throughput microscopy. Molecular Biology and Evolution. 30: 2568-78. PMID 23938868 DOI: 10.1093/Molbev/Mst138  1
2013 Conley D, Rauscher E, Dawes C, Magnusson PK, Siegal ML. Heritability and the equal environments assumption: evidence from multiple samples of misclassified twins. Behavior Genetics. 43: 415-26. PMID 23903437 DOI: 10.1007/S10519-013-9602-1  1
2013 Conley D, Rauscher E, Siegal ML. Beyond orchids and dandelions: testing the 5-HTT "risky" allele for evidence of phenotypic capacitance and frequency-dependent selection. Biodemography and Social Biology. 59: 37-56. PMID 23701535 DOI: 10.1080/19485565.2013.774620  1
2013 Geiler-Samerotte KA, Bauer CR, Li S, Ziv N, Gresham D, Siegal ML. The details in the distributions: why and how to study phenotypic variability. Current Opinion in Biotechnology. 24: 752-9. PMID 23566377 DOI: 10.1016/J.Copbio.2013.03.010  1
2013 Siegal ML. Crouching variation revealed. Molecular Ecology. 22: 1187-9. PMID 23437837 DOI: 10.1111/mec.12195  1
2012 Schnakenberg SL, Siegal ML, Bloch Qazi MC. Oh, the places they'll go: Female sperm storage and sperm precedence in Drosophila melanogaster. Spermatogenesis. 2: 224-235. PMID 23087839 DOI: 10.4161/spmg.21655  0.84
2012 Levy SF, Siegal ML. The robustness continuum. Advances in Experimental Medicine and Biology. 751: 431-52. PMID 22821470 DOI: 10.1007/978-1-4614-3567-9_20  1
2012 Fraser HB, Levy S, Chavan A, Shah HB, Perez JC, Zhou Y, Siegal ML, Sinha H. Polygenic cis-regulatory adaptation in the evolution of yeast pathogenicity. Genome Research. 22: 1930-9. PMID 22645260 DOI: 10.1101/Gr.134080.111  1
2012 Siegal ML, Rushlow C. Pausing on the path to robustness. Developmental Cell. 22: 905-6. PMID 22595664 DOI: 10.1016/J.Devcel.2012.04.020  1
2012 Levy SF, Ziv N, Siegal ML. Bet hedging in yeast by heterogeneous, age-correlated expression of a stress protectant. Plos Biology. 10: e1001325. PMID 22589700 DOI: 10.1371/Journal.Pbio.1001325  1
2012 Siegal ML, Masel J. Hsp90 depletion goes wild. Bmc Biology. 10: 14. PMID 22369621 DOI: 10.1186/1741-7007-10-14  1
2011 Schnakenberg SL, Matias WR, Siegal ML. Sperm-storage defects and live birth in Drosophila females lacking spermathecal secretory cells. Plos Biology. 9: e1001192. PMID 22087073 DOI: 10.1371/Journal.Pbio.1001192  1
2011 Chatterjee SS, Uppendahl LD, Chowdhury MA, Ip PL, Siegal ML. The female-specific doublesex isoform regulates pleiotropic transcription factors to pattern genital development in Drosophila. Development (Cambridge, England). 138: 1099-109. PMID 21343364 DOI: 10.1242/Dev.055731  1
2010 Arbeitman MN, Kopp A, Siegal ML, Van Doren M. Everything you always wanted to know about sex ... in flies. Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation. 4: 315-20. PMID 20926851 DOI: 10.1159/000320632  1
2010 Chen K, van Nimwegen E, Rajewsky N, Siegal ML. Correlating gene expression variation with cis-regulatory polymorphism in Saccharomyces cerevisiae. Genome Biology and Evolution. 2: 697-707. PMID 20829281 DOI: 10.1093/gbe/evq054  1
2010 Arbeitman MN, Kopp A, Siegal ML, Doren MV, Lorenzi LD, Genualdo V, Iannuzzi A, Meo GPD, Perucatti A, Mancuso R, Russo M, Berardino DD, Parma P, Iannuzzi L, Georg I, et al. Contents Vol. 4, 2010 Sexual Development. 4. DOI: 10.1159/000321686  0.6
2009 Masel J, Siegal ML. Robustness: mechanisms and consequences. Trends in Genetics : Tig. 25: 395-403. PMID 19717203 DOI: 10.1016/J.Tig.2009.07.005  1
2009 Chen K, Maaskola J, Siegal ML, Rajewsky N. Reexamining microRNA site accessibility in Drosophila: a population genomics study. Plos One. 4: e5681. PMID 19478854 DOI: 10.1371/journal.pone.0005681  1
2008 Levy SF, Siegal ML. Network hubs buffer environmental variation in Saccharomyces cerevisiae. Plos Biology. 6: e264. PMID 18986213 DOI: 10.1371/Journal.Pbio.0060264  1
2007 Siegal ML, Promislow DE, Bergman A. Functional and evolutionary inference in gene networks: does topology matter? Genetica. 129: 83-103. PMID 16897451 DOI: 10.1007/S10709-006-0035-0  1
2005 Siegal ML, Baker BS. Functional conservation and divergence of intersex, a gene required for female differentiation in Drosophila melanogaster. Development Genes and Evolution. 215: 1-12. PMID 15645316 DOI: 10.1007/s00427-004-0445-x  1
2004 Arbeitman MN, Fleming AA, Siegal ML, Null BH, Baker BS. A genomic analysis of Drosophila somatic sexual differentiation and its regulation. Development (Cambridge, England). 131: 2007-21. PMID 15056610 DOI: 10.1242/Dev.01077  1
2003 Bergman A, Siegal ML. Evolutionary capacitance as a general feature of complex gene networks. Nature. 424: 549-52. PMID 12891357 DOI: 10.1038/Nature01765  1
2002 Garrett-Engele CM, Siegal ML, Manoli DS, Williams BC, Li H, Baker BS. intersex, a gene required for female sexual development in Drosophila, is expressed in both sexes and functions together with doublesex to regulate terminal differentiation. Development (Cambridge, England). 129: 4661-75. PMID 12361959  1
2002 Siegal ML, Bergman A. Waddington's canalization revisited: developmental stability and evolution. Proceedings of the National Academy of Sciences of the United States of America. 99: 10528-32. PMID 12082173 DOI: 10.1073/Pnas.102303999  1
2000 Marín I, Siegal ML, Baker BS. The evolution of dosage-compensation mechanisms. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 22: 1106-14. PMID 11084626 DOI: 10.1002/1521-1878(200012)22:12<1106::AID-BIES8>3.0.CO;2-W  1
2000 Siegal ML, Hartl DL. Application of Cre/loxP in Drosophila. Site-specific recombination and transgene coplacement. Methods in Molecular Biology (Clifton, N.J.). 136: 487-95. PMID 10840736 DOI: 10.1385/1-59259-065-9:487  1
1999 Siegal ML, Hartl DL. Oviposition-site preference in Drosophila following interspecific gene transfer of the Alcohol dehydrogenase locus. Behavior Genetics. 29: 199-204. PMID 10547927 DOI: 10.1023/A:1021648103496  1
1998 Siegal ML, Hartl DL. An experimental test for lineage-specific position effects on alcohol dehydrogenase (Adh) genes in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 95: 15513-8. PMID 9861000 DOI: 10.1073/Pnas.95.26.15513  1
1996 Siegal ML, Petrov DA, De Aguiar D. Triple-ligation strategy with advantages over directional cloning. Biotechniques. 21: 614, 616, 618-9. PMID 8891209 DOI: 10.2144/96214Bm09  1
1996 Siegal ML, Hartl DL. Transgene Coplacement and high efficiency site-specific recombination with the Cre/loxP system in Drosophila. Genetics. 144: 715-26. PMID 8889532  1
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