Bruce Hay - Publications


70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hay BA, Oberhofer G, Guo M. Engineering the Composition and Fate of Wild Populations with Gene Drive. Annual Review of Entomology. PMID 33035437 DOI: 10.1146/annurev-ento-020117-043154  0.6
2017 Hay BA, Li J, Guo M. Vectored gene delivery for lifetime animal contraception: Overview and hurdles to implementation. Theriogenology. PMID 29169734 DOI: 10.1016/j.theriogenology.2017.11.003  0.6
2017 Kandul N, Guo M, Hay BA. A positive readout single transcript reporter for site-specific mRNA cleavage. Peerj. 5: e3602. PMID 28740759 DOI: 10.7717/peerj.3602  0.6
2017 Zhang T, Mishra P, Hay BA, Chan D, Guo M. Valosin-containing protein (VCP/p97) inhibitors relieve Mitofusin-dependent mitochondrial defects due to VCP disease mutants. Elife. 6. PMID 28322724 DOI: 10.7554/eLife.17834  0.6
2016 Kandul NP, Zhang T, Hay BA, Guo M. Selective removal of deletion-bearing mitochondrial DNA in heteroplasmic Drosophila. Nature Communications. 7: 13100. PMID 27841259 DOI: 10.1038/ncomms13100  0.6
2015 Li J, Olvera AI, Akbari OS, Moradian A, Sweredoski MJ, Hess S, Hay BA. Vectored antibody gene delivery mediates long-term contraception. Current Biology : Cb. 25: R820-2. PMID 26439332 DOI: 10.1016/j.cub.2015.08.002  1
2014 Marshall JM, Hay BA. Medusa: a novel gene drive system for confined suppression of insect populations. Plos One. 9: e102694. PMID 25054803 DOI: 10.1371/journal.pone.0102694  1
2014 Akbari OS, Papathanos PA, Sandler JE, Kennedy K, Hay BA. Identification of germline transcriptional regulatory elements in Aedes aegypti. Scientific Reports. 4: 3954. PMID 24492376 DOI: 10.1038/srep03954  1
2014 Akbari OS, Chen CH, Marshall JM, Huang H, Antoshechkin I, Hay BA. Novel synthetic Medea selfish genetic elements drive population replacement in Drosophila; a theoretical exploration of Medea-dependent population suppression. Acs Synthetic Biology. 3: 915-28. PMID 23654248 DOI: 10.1021/sb300079h  1
2013 Akbari OS, Antoshechkin I, Hay BA, Ferree PM. Transcriptome profiling of Nasonia vitripennis testis reveals novel transcripts expressed from the selfish B chromosome, paternal sex ratio. G3 (Bethesda, Md.). 3: 1597-605. PMID 23893741 DOI: 10.1534/g3.113.007583  1
2013 Akbari OS, Antoshechkin I, Amrhein H, Williams B, Diloreto R, Sandler J, Hay BA. The developmental transcriptome of the mosquito Aedes aegypti, an invasive species and major arbovirus vector. G3 (Bethesda, Md.). 3: 1493-509. PMID 23833213 DOI: 10.1534/g3.113.006742  1
2013 Akbari OS, Matzen KD, Marshall JM, Huang H, Ward CM, Hay BA. A synthetic gene drive system for local, reversible modification and suppression of insect populations. Current Biology : Cb. 23: 671-7. PMID 23541732 DOI: 10.1016/j.cub.2013.02.059  1
2012 Marshall JM, Hay BA. General principles of single-construct chromosomal gene drive. Evolution; International Journal of Organic Evolution. 66: 2150-66. PMID 22759292 DOI: 10.1111/j.1558-5646.2012.01582.x  1
2012 Rochet JC, Hay BA, Guo M. Molecular insights into Parkinson's disease. Progress in Molecular Biology and Translational Science. 107: 125-88. PMID 22482450 DOI: 10.1016/B978-0-12-385883-2.00011-4  1
2012 Marshall JM, Hay BA. Confinement of gene drive systems to local populations: a comparative analysis. Journal of Theoretical Biology. 294: 153-71. PMID 22094363 DOI: 10.1016/j.jtbi.2011.10.032  1
2011 Marshall JM, Hay BA. Inverse Medea as a novel gene drive system for local population replacement: a theoretical analysis. The Journal of Heredity. 102: 336-41. PMID 21493596 DOI: 10.1093/jhered/esr019  1
2011 Lee G, Wang Z, Sehgal R, Chen CH, Kikuno K, Hay B, Park JH. Drosophila caspases involved in developmentally regulated programmed cell death of peptidergic neurons during early metamorphosis. The Journal of Comparative Neurology. 519: 34-48. PMID 21120926 DOI: 10.1002/cne.22498  1
2011 Marshall JM, Pittman GW, Buchman AB, Hay BA. Semele: a killer-male, rescue-female system for suppression and replacement of insect disease vector populations. Genetics. 187: 535-51. PMID 21078687 DOI: 10.1534/genetics.110.124479  1
2011 Ward CM, Su JT, Huang Y, Lloyd AL, Gould F, Hay BA. Medea selfish genetic elements as tools for altering traits of wild populations: a theoretical analysis. Evolution; International Journal of Organic Evolution. 65: 1149-62. PMID 21062278 DOI: 10.1111/j.1558-5646.2010.01186.x  1
2010 Hay BA, Chen CH, Ward CM, Huang H, Su JT, Guo M. Engineering the genomes of wild insect populations: challenges, and opportunities provided by synthetic Medea selfish genetic elements. Journal of Insect Physiology. 56: 1402-13. PMID 20570677 DOI: 10.1016/j.jinsphys.2010.05.022  1
2010 Siegrist SE, Haque NS, Chen CH, Hay BA, Hariharan IK. Inactivation of both Foxo and reaper promotes long-term adult neurogenesis in Drosophila. Current Biology : Cb. 20: 643-8. PMID 20346676 DOI: 10.1016/j.cub.2010.01.060  1
2009 Ribaya JP, Ranmuthu M, Copeland J, Boyarskiy S, Blair AP, Hay B, Laski FA. The deubiquitinase emperor's thumb is a regulator of apoptosis in Drosophila. Developmental Biology. 329: 25-35. PMID 19217892 DOI: 10.1016/j.ydbio.2009.02.005  1
2008 Hawkins JL, Robbins MD, Warren LC, Xia D, Petras SF, Valentine JJ, Varghese AH, Wang IK, Subashi TA, Shelly LD, Hay BA, Landschulz KT, Geoghegan KF, Harwood HJ. Pharmacologic inhibition of site 1 protease activity inhibits sterol regulatory element-binding protein processing and reduces lipogenic enzyme gene expression and lipid synthesis in cultured cells and experimental animals. The Journal of Pharmacology and Experimental Therapeutics. 326: 801-8. PMID 18577702 DOI: 10.1124/jpet.108.139626  1
2008 Sathyanarayanan S, Zheng X, Kumar S, Chen CH, Chen D, Hay B, Sehgal A. Identification of novel genes involved in light-dependent CRY degradation through a genome-wide RNAi screen. Genes & Development. 22: 1522-33. PMID 18519643 DOI: 10.1101/gad.1652308  1
2008 Yao JG, Weasner BM, Wang LH, Jang CC, Weasner B, Tang CY, Salzer CL, Chen CH, Hay B, Sun YH, Kumar JP. Differential requirements for the Pax6(5a) genes eyegone and twin of eyegone during eye development in Drosophila. Developmental Biology. 315: 535-51. PMID 18275947 DOI: 10.1016/j.ydbio.2007.12.037  1
2007 Shcherbata HR, Ward EJ, Fischer KA, Yu JY, Reynolds SH, Chen CH, Xu P, Hay BA, Ruohola-Baker H. Stage-specific differences in the requirements for germline stem cell maintenance in the Drosophila ovary. Cell Stem Cell. 1: 698-709. PMID 18213359 DOI: 10.1016/j.stem.2007.11.007  1
2007 Copeland JM, Bosdet I, Freeman JD, Guo M, Gorski SM, Hay BA. echinus, required for interommatidial cell sorting and cell death in the Drosophila pupal retina, encodes a protein with homology to ubiquitin-specific proteases. Bmc Developmental Biology. 7: 82. PMID 17612403 DOI: 10.1186/1471-213X-7-82  1
2007 Hay BA, Abrams B, Zumbrunn AY, Valentine JJ, Warren LC, Petras SF, Shelly LD, Xia A, Varghese AH, Hawkins JL, Van Camp JA, Robbins MD, Landschulz K, Harwood HJ. Aminopyrrolidineamide inhibitors of site-1 protease. Bioorganic & Medicinal Chemistry Letters. 17: 4411-4. PMID 17583500 DOI: 10.1016/j.bmcl.2007.06.031  1
2007 Chen CH, Huang H, Ward CM, Su JT, Schaeffer LV, Guo M, Hay BA. A synthetic maternal-effect selfish genetic element drives population replacement in Drosophila. Science (New York, N.Y.). 316: 597-600. PMID 17395794 DOI: 10.1126/science. 1138595  1
2007 Huh JR, Foe I, Muro I, Chen CH, Seol JH, Yoo SJ, Guo M, Park JM, Hay BA. The Drosophila inhibitor of apoptosis (IAP) DIAP2 is dispensable for cell survival, required for the innate immune response to gram-negative bacterial infection, and can be negatively regulated by the reaper/hid/grim family of IAP-binding apoptosis inducers. The Journal of Biological Chemistry. 282: 2056-68. PMID 17068333 DOI: 10.1074/jbc.M608051200  1
2006 Chen CH, Guo M, Hay BA. Identifying microRNA regulators of cell death in Drosophila. Methods in Molecular Biology (Clifton, N.J.). 342: 229-40. PMID 16957378 DOI: 10.1385/1-59745-123-1:229  1
2006 Muro I, Berry DL, Huh JR, Chen CH, Huang H, Yoo SJ, Guo M, Baehrecke EH, Hay BA. The Drosophila caspase Ice is important for many apoptotic cell deaths and for spermatid individualization, a nonapoptotic process. Development (Cambridge, England). 133: 3305-15. PMID 16887831 DOI: 10.1242/dev.02495  1
2006 Hay BA, Guo M. Caspase-dependent cell death in Drosophila. Annual Review of Cell and Developmental Biology. 22: 623-50. PMID 16842034 DOI: 10.1146/annurev.cellbio.21.012804.093845  1
2006 Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, Seol JH, Yoo SJ, Hay BA, Guo M. Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature. 441: 1162-6. PMID 16672981 DOI: 10.1038/nature04779  1
2006 Yan N, Huh JR, Schirf V, Demeler B, Hay BA, Shi Y. Structure and activation mechanism of the Drosophila initiator caspase Dronc. The Journal of Biological Chemistry. 281: 8667-74. PMID 16446367 DOI: 10.1074/jbc.M513232200  1
2004 Hay BA, Huh JR, Guo M. The genetics of cell death: approaches, insights and opportunities in Drosophila. Nature Reviews. Genetics. 5: 911-22. PMID 15573123 DOI: 10.1038/nrg1491  1
2004 Xu P, Guo M, Hay BA. MicroRNAs and the regulation of cell death. Trends in Genetics : Tig. 20: 617-24. PMID 15522457 DOI: 10.1016/j.tig.2004.09.010  1
2004 Huh JR, Guo M, Hay BA. Compensatory proliferation induced by cell death in the Drosophila wing disc requires activity of the apical cell death caspase Dronc in a nonapoptotic role. Current Biology : Cb. 14: 1262-6. PMID 15268856 DOI: 10.1016/j.cub.2004.06.015  1
2004 Huh JR, Vernooy SY, Yu H, Yan N, Shi Y, Guo M, Hay BA. Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization. Plos Biology. 2: E15. PMID 14737191 DOI: 10.1371/journal.pbio.0020015  1
2003 Chai J, Yan N, Huh JR, Wu JW, Li W, Hay BA, Shi Y. Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination. Nature Structural Biology. 10: 892-8. PMID 14517550 DOI: 10.1038/nsb989  1
2003 Hay BA, Guo M. Coupling cell growth, proliferation, and death. Hippo weighs in. Developmental Cell. 5: 361-3. PMID 12967554 DOI: 10.1016/S1534-5807(03)00270-3  1
2003 Guo M, Hong EJ, Fernandes J, Zipursky SL, Hay BA. A reporter for amyloid precursor protein gamma-secretase activity in Drosophila. Human Molecular Genetics. 12: 2669-78. PMID 12944419 DOI: 10.1093/hmg/ddg292  1
2003 Xu P, Vernooy SY, Guo M, Hay BA. The Drosophila microRNA Mir-14 suppresses cell death and is required for normal fat metabolism. Current Biology : Cb. 13: 790-5. PMID 12725740 DOI: 10.1016/S0960-9822(03)00250-1  1
2003 Olson MR, Holley CL, Yoo SJ, Huh JR, Hay BA, Kornbluth S. Reaper is regulated by IAP-mediated ubiquitination. The Journal of Biological Chemistry. 278: 4028-34. PMID 12446669 DOI: 10.1074/jbc.M209734200  1
2002 Muro I, Hay BA, Clem RJ. The Drosophila DIAP1 protein is required to prevent accumulation of a continuously generated, processed form of the apical caspase DRONC. The Journal of Biological Chemistry. 277: 49644-50. PMID 12397080 DOI: 10.1074/jbc.M203464200  1
2002 Huh JR, Hay BA. Apoptosis: sculpture of a fly's head. Nature. 418: 926-8. PMID 12198529 DOI: 10.1038/418926a  1
2002 Vernooy SY, Chow V, Su J, Verbrugghe K, Yang J, Cole S, Olson MR, Hay BA. Drosophila Bruce can potently suppress Rpr- and Grim-dependent but not Hid-dependent cell death. Current Biology : Cb. 12: 1164-8. PMID 12121627 DOI: 10.1016/S0960-9822(02)00935-1  1
2002 Yu SY, Yoo SJ, Yang L, Zapata C, Srinivasan A, Hay BA, Baker NE. A pathway of signals regulating effector and initiator caspases in the developing Drosophila eye. Development (Cambridge, England). 129: 3269-78. PMID 12070100  1
2002 Yoo SJ, Huh JR, Muro I, Yu H, Wang L, Wang SL, Feldman RM, Clem RJ, Müller HA, Hay BA. Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms. Nature Cell Biology. 4: 416-24. PMID 12021767 DOI: 10.1038/ncb793  1
2002 Dorstyn L, Read S, Cakouros D, Huh JR, Hay BA, Kumar S. The role of cytochrome c in caspase activation in Drosophila melanogaster cells. The Journal of Cell Biology. 156: 1089-98. PMID 11901173 DOI: 10.1083/jcb.200111107  1
2001 Hay BA, Cole BM, DiCapua F, Kirk GW, Murray MC, Nardone RA, Pelletier DJ, Ricketts AP, Robertson AS, Siegel TW. Small molecule somatostatin receptor subtype-2 antagonists Bioorganic and Medicinal Chemistry Letters. 11: 2731-2734. PMID 11591512 DOI: 10.1016/S0960-894X(01)00568-6  1
2001 Wu JW, Cocina AE, Chai J, Hay BA, Shi Y. Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides. Molecular Cell. 8: 95-104. PMID 11511363 DOI: 10.1016/S1097-2765(01)00282-9  1
2000 Hay BA. Understanding IAP function and regulation: A view from Drosophila Cell Death and Differentiation. 7: 1045-1056. PMID 11139277  1
2000 Hawkins CJ, Wang SL, Hay BA. Monitoring activity of caspases and their regulators in yeast Saccharomyces cerevisiae Methods in Enzymology. 322: 162-174. PMID 10914013  1
2000 Vernooy SY, Copeland J, Ghaboosi N, Griffin EE, Yoo SJ, Hay BA. Cell death regulation in Drosophila: conservation of mechanism and unique insights. The Journal of Cell Biology. 150: F69-76. PMID 10908589 DOI: 10.1083/jcb.150.2.F69  1
2000 Hawkins CJ, Yoo SJ, Peterson EP, Wang SL, Vernooy SY, Hay BA. The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM. The Journal of Biological Chemistry. 275: 27084-93. PMID 10825159 DOI: 10.1074/jbc.M000869200  1
2000 Rubin GM, Yandell MD, Wortman JR, Gabor Miklos GL, Nelson CR, Hariharan IK, Fortini ME, Li PW, Apweiler R, Fleischmann W, Cherry JM, Henikoff S, Skupski MP, Misra S, Ashburner M, ... ... Hay BA, et al. Comparative genomics of the eukaryotes. Science (New York, N.Y.). 287: 2204-15. PMID 10731134 DOI: 10.1126/science.287.5461.2204  1
1999 Guo M, Hay BA. Cell proliferation and apoptosis Current Opinion in Cell Biology. 11: 745-752. PMID 10600713 DOI: 10.1016/S0955-0674(99)00046-0  1
1999 Wang SL, Hawkins CJ, Yoo SJ, Müller HAJ, Hay BA. The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID Cell. 98: 453-463. PMID 10481910 DOI: 10.1016/S0092-8674(00)81974-1  1
1999 Hawkins CJ, Wang SL, Hay BA. A cloning method to identify caspases and their regulators in yeast: Identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1 Proceedings of the National Academy of Sciences of the United States of America. 96: 2885-2890. PMID 10077606 DOI: 10.1073/pnas.96.6.2885  1
1997 Hay BA, Maile R, Rubin GM. P element insertion-dependent gene activation in the Drosophila eye. Proceedings of the National Academy of Sciences of the United States of America. 94: 5195-200. PMID 9144214 DOI: 10.1073/pnas.94.10.5195  1
1995 Hay BA, Wassarman DA, Rubin GM. Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death. Cell. 83: 1253-62. PMID 8548811 DOI: 10.1016/0092-8674(95)90150-7  1
1994 Hay BA, Wolff T, Rubin GM. Expression of baculovirus P35 prevents cell death in Drosophila. Development (Cambridge, England). 120: 2121-9. PMID 7925015  1
1992 Jongens TA, Hay B, Jan LY, Jan YN. The germ cell-less gene product: a posteriorly localized component necessary for germ cell development in Drosophila. Cell. 70: 569-84. PMID 1380406 DOI: 10.1016/0092-8674(92)90427-E  1
1990 Hay B, Jan LY, Jan YN. Localization of vasa, a component of Drosophila polar granules, in maternal-effect mutants that alter embryonic anteroposterior polarity Development. 109: 425-433. PMID 2119289  1
1988 Hay B, Ackerman L, Barbel S, Jan LY, Jan YN. Identification of a component of Drosophila polar granules Development. 103: 625-640. PMID 3150351  1
1988 Hay B, Jan LY, Jan YN. A protein component of Drosophila polar granules is encoded by vasa and has extensive sequence similarity to ATP-dependent helicases Cell. 55: 577-587. PMID 3052853 DOI: 10.1016/0092-8674(88)90216-4  1
1987 McKinley MP, Hay B, Lingappa VR, Lieberburg I, Prusiner SB. Developmental expression of prion protein gene in brain. Developmental Biology. 121: 105-10. PMID 3569656 DOI: 10.1016/0012-1606(87)90143-6  1
1987 Hay B, Barry RA, Lieberburg I, Prusiner SB, Lingappa VR. Biogenesis and transmembrane orientation of the cellular isoform of the scrapie prion protein [published errratum appears in Mol Cell Biol 1987 May;7(5):2035]. Molecular and Cellular Biology. 7: 914-20. PMID 3547085  1
1987 Hay B, Prusiner SB, Lingappa VR. Evidence for a secretory form of the cellular prion protein. Biochemistry. 26: 8110-5. PMID 3126796  1
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