Marc Therrien - Publications

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137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Gavory G, Baril C, Laberge G, Bidla G, Koonpaew S, Sonea T, Sauvageau G, Therrien M. A genetic screen in Drosophila uncovers the multifaceted properties of the NUP98-HOXA9 oncogene. Plos Genetics. 17: e1009730. PMID 34383740 DOI: 10.1371/journal.pgen.1009730  1
2020 Posternak G, Tang X, Maisonneuve P, Jin T, Lavoie H, Daou S, Orlicky S, Goullet de Rugy T, Caldwell L, Chan K, Aman A, Prakesch M, Poda G, Mader P, Wong C, ... ... Therrien M, et al. Functional characterization of a PROTAC directed against BRAF mutant V600E. Nature Chemical Biology. PMID 32778845 DOI: 10.1038/S41589-020-0609-7  1
2020 Lavoie H, Gagnon J, Therrien M. ERK signalling: a master regulator of cell behaviour, life and fate. Nature Reviews. Molecular Cell Biology. PMID 32576977 DOI: 10.1038/s41580-020-0255-7  1
2018 Daou S, Barbour H, Ahmed O, Masclef L, Baril C, Sen Nkwe N, Tchelougou D, Uriarte M, Bonneil E, Ceccarelli D, Mashtalir N, Tanji M, Masson JY, Thibault P, Sicheri F, ... ... Therrien M, et al. Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1. Nature Communications. 9: 4385. PMID 30349006 DOI: 10.1038/S41467-018-06854-2  1
2018 Rauen KA, Schoyer L, Schill L, Stronach B, Albeck J, Andresen BS, Cavé H, Ellis M, Fruchtman SM, Gelb BD, Gibson CC, Gripp K, Hefner E, Huang WYC, Itkin M, ... ... Therrien M, et al. Proceedings of the fifth international RASopathies symposium: When development and cancer intersect. American Journal of Medical Genetics. Part A. e40632. PMID 30302932 DOI: 10.1002/Ajmg.A.40632  1
2018 Lavoie H, Sahmi M, Maisonneuve P, Marullo SA, Thevakumaran N, Jin T, Kurinov I, Sicheri F, Therrien M. MEK drives BRAF activation through allosteric control of KSR proteins. Nature. PMID 29433126 DOI: 10.1038/Nature25478  1
2017 Jin T, Lavoie H, Sahmi M, David M, Hilt C, Hammell A, Therrien M. RAF inhibitors promote RAS-RAF interaction by allosterically disrupting RAF autoinhibition. Nature Communications. 8: 1211. PMID 29084939 DOI: 10.1038/s41467-017-01274-0  1
2017 Kubiniok P, Lavoie H, Therrien M, Thibault P. Time-resolved phosphoproteome analysis of paradoxical RAF activation reveals novel targets of ERK. Molecular & Cellular Proteomics : McP. PMID 28188228 DOI: 10.1074/Mcp.M116.065128  1
2017 Ashton-Beaucage D, Therrien M. How Genetics Has Helped Piece Together the MAPK Signaling Pathway. Methods in Molecular Biology (Clifton, N.J.). 1487: 1-21. PMID 27924555 DOI: 10.1007/978-1-4939-6424-6_1  1
2016 Baril C, Gavory G, Bidla G, Knævelsrud H, Sauvageau G, Therrien M. Human NUP98-HOXA9 promotes hyperplastic growth of hematopoietic tissues in Drosophila. Developmental Biology. PMID 27838340 DOI: 10.1016/J.Ydbio.2016.11.003  1
2016 Spencer-Smith R, Koide A, Zhou Y, Eguchi RR, Sha F, Gajwani P, Santana D, Gupta A, Jacobs M, Herrero-Garcia E, Cobbert J, Lavoie H, Smith M, Rajakulendran T, Dowdell E, ... ... Therrien M, et al. Inhibition of RAS function through targeting an allosteric regulatory site. Nature Chemical Biology. PMID 27820802 DOI: 10.1038/Nchembio.2231  1
2016 Brunet JF, Dagenais D, Therrien M, Gartenberg D, Forest G. Validation of sleep-2-Peak: A smartphone application that can detect fatigue-related changes in reaction times during sleep deprivation. Behavior Research Methods. PMID 27631990 DOI: 10.3758/S13428-016-0802-5  1
2016 Ashton-Beaucage D, Lemieux C, Udell CM, Sahmi M, Rochette S, Therrien M. The Deubiquitinase USP47 Stabilizes MAPK by Counteracting the Function of the N-end Rule ligase POE/UBR4 in Drosophila. Plos Biology. 14: e1002539. PMID 27552662 DOI: 10.1371/journal.pbio.1002539  1
2015 Wilkinson KM, Dennis NA, Webb CE, Therrien M, Stradtman M, Farmer J, Leach R, Warrenfeltz M, Zeuner C. Neural Activity Associated with Visual Search for Line Drawings on AAC Displays: An Exploration of the Use of fMRI. Augmentative and Alternative Communication (Baltimore, Md. : 1985). 31: 310-24. PMID 26517757 DOI: 10.3109/07434618.2015.1100215  1
2015 Lee S, Sohal IS, Therrien MA, Pal AK, Bello D, Shea TB. Additive Impairment of Synaptic Signaling in Cultured Cortical Neurons by Exogenously-Applied Oligomerized Amyloid-β and Airborne Nanoparticles Generated during Photocopying. Journal of Alzheimer's Disease : Jad. 47: 49-54. PMID 26402753 DOI: 10.3233/Jad-150099  1
2015 Lavoie H, Therrien M. Regulation of RAF protein kinases in ERK signalling. Nature Reviews. Molecular Cell Biology. 16: 281-98. PMID 25907612 DOI: 10.1038/nrm3979  1
2015 Therrien M, Byham-Gray L, Beto J. A Review of Dietary Intake Studies in Maintenance Dialysis Patients. Journal of Renal Nutrition : the Official Journal of the Council On Renal Nutrition of the National Kidney Foundation. 25: 329-338. PMID 25592493 DOI: 10.1053/J.Jrn.2014.11.001  1
2015 Thevakumaran N, Lavoie H, Critton DA, Tebben A, Marinier A, Sicheri F, Therrien M. Crystal structure of a BRAF kinase domain monomer explains basis for allosteric regulation. Nature Structural & Molecular Biology. 22: 37-43. PMID 25437913 DOI: 10.1038/Nsmb.2924  1
2015 Therrien MC, Beauregard S, Valiquette-L’Heureux A. Iterative Factors Favoring Collaboration for Interorganizational Resilience: The Case of the Greater Montréal Transportation Infrastructure International Journal of Disaster Risk Science. 6: 75-86. DOI: 10.1007/s13753-015-0044-7  1
2014 Therrien M, Parker JA. Deciphering genetic interactions between ALS genes using C. elegans. Worm. 3: e29047. PMID 25254150 DOI: 10.4161/worm.29047  0.01
2014 Lavoie H, Li JJ, Thevakumaran N, Therrien M, Sicheri F. Dimerization-induced allostery in protein kinase regulation. Trends in Biochemical Sciences. 39: 475-86. PMID 25220378 DOI: 10.1016/J.Tibs.2014.08.004  1
2014 Lee S, Zemianek JM, Shultz A, Vo A, Maron BY, Therrien M, Courtright C, Guaraldi M, Yanco HA, Shea TB. Synaptic signal streams generated by ex vivo neuronal networks contain non-random, complex patterns. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 38: 184-94. PMID 25172170 DOI: 10.1016/J.Ijdevneu.2014.08.008  1
2014 Shivamurthy P, Brar N, Therrien ML. Isolated hemopericardium associated with rivaroxaban: first case report. Pharmacotherapy. 34: e169-72. PMID 25074401 DOI: 10.1002/phar.1474  1
2014 Baril C, Lefrançois M, Sahmi M, Knævelsrud H, Therrien M. Apical accumulation of the Sevenless receptor tyrosine kinase during Drosophila eye development is promoted by the small GTPase Rap1. Genetics. 197: 1237-50. PMID 24899161 DOI: 10.1534/genetics.114.166272  1
2014 Therrien M, Parker JA. Worming forward: amyotrophic lateral sclerosis toxicity mechanisms and genetic interactions in Caenorhabditis elegans. Frontiers in Genetics. 5: 85. PMID 24860590 DOI: 10.3389/fgene.2014.00085  1
2014 Mashtalir N, Daou S, Barbour H, Sen NN, Gagnon J, Hammond-Martel I, Dar HH, Therrien M, Affar el B. Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O. Molecular Cell. 54: 392-406. PMID 24703950 DOI: 10.1016/j.molcel.2014.03.002  1
2014 Ashton-Beaucage D, Udell CM, Gendron P, Sahmi M, Lefrançois M, Baril C, Guenier AS, Duchaine J, Lamarre D, Lemieux S, Therrien M. A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila. Plos Biology. 12: e1001809. PMID 24643257 DOI: 10.1371/Journal.Pbio.1001809  1
2014 Therrien M, Byham-Gray L, Denmark R, Beto J. Comparison of dietary intake among women on maintenance dialysis to a Women's Health Initiative cohort: results from the NKF-CRN Second National Research Question Collaborative Study. Journal of Renal Nutrition : the Official Journal of the Council On Renal Nutrition of the National Kidney Foundation. 24: 72-80. PMID 24290672 DOI: 10.1053/J.Jrn.2013.09.005  1
2013 Therrien M, Rouleau GA, Dion PA, Parker JA. Deletion of C9ORF72 results in motor neuron degeneration and stress sensitivity in C. elegans. Plos One. 8: e83450. PMID 24349511 DOI: 10.1371/Journal.Pone.0083450  1
2013 Lavoie H, Thevakumaran N, Gavory G, Li JJ, Padeganeh A, Guiral S, Duchaine J, Mao DY, Bouvier M, Sicheri F, Therrien M. Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization. Nature Chemical Biology. 9: 428-36. PMID 23685672 DOI: 10.1038/Nchembio.1257  1
2013 Nadeau S, Bouchard M, Debia M, DeMarcellis-Warin N, Hallé S, Songmene V, Therrien MC, Wilkinson K, Ateme-Nguema B, Dufour G, Dufresne A, Fatisson J, Haddad S, Hadioui M, Kouam J, et al. ÉquiNanos: innovative team for nanoparticle risk management. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 22-4. PMID 22960193 DOI: 10.1016/J.Nano.2012.08.003  1
2013 Dumond DA, Stacy W, Geyer A, Rousseau J, Therrien M. Cognitive patterns: Giving autonomy some context Proceedings of Spie - the International Society For Optical Engineering. 8741. DOI: 10.1117/12.2016383  1
2013 Valiquette L'Heureux A, Therrien MC. Interorganizational dynamics and characteristics of critical infrastructure networks: The study of three critical infrastructures in the greater montreal area Journal of Contingencies and Crisis Management. 21: 211-224. DOI: 10.1111/1468-5973.12030  1
2013 Tanguay GA, Rajaonson J, Therrien MC. Sustainable tourism indicators: Selection criteria for policy implementation and scientific recognition Journal of Sustainable Tourism. 21: 862-879. DOI: 10.1080/09669582.2012.742531  1
2013 Wedlich RC, Libera AE, Pires A, Therrien MT. Good laboratory practice. Part 1. An introduction Journal of Chemical Education. 90: 854-857. DOI: 10.1021/ed3002545  1
2012 Collin CA, Therrien ME, Campbell KB, Hamm JP. Effects of band-pass spatial frequency filtering of face and object images on the amplitude of N170. Perception. 41: 717-32. PMID 23094460 DOI: 10.1068/p7056  1
2012 Vaccaro A, Patten SA, Ciura S, Maios C, Therrien M, Drapeau P, Kabashi E, Parker JA. Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio. Plos One. 7: e42117. PMID 22848727 DOI: 10.1371/Journal.Pone.0042117  1
2012 Williams V, Rousculp MD, Price M, Coles T, Therrien M, Griffin J, Hollis K, Toback S. Elementary school-located influenza vaccine programs: key stakeholder experiences from initiation to continuation. The Journal of School Nursing : the Official Publication of the National Association of School Nurses. 28: 256-67. PMID 22427316 DOI: 10.1177/1059840512438776  1
2012 Stochmanski SJ, Therrien M, Laganière J, Rochefort D, Laurent S, Karemera L, Gaudet R, Vyboh K, Van Meyel DJ, Di Cristo G, Dion PA, Gaspar C, Rouleau GA. Expanded ATXN3 frameshifting events are toxic in Drosophila and mammalian neuron models. Human Molecular Genetics. 21: 2211-8. PMID 22337953 DOI: 10.1093/Hmg/Dds036  1
2012 McSpadden C, Therrien M, McEwen IR. Care coordination for children with special health care needs and roles for physical therapists. Pediatric Physical Therapy : the Official Publication of the Section On Pediatrics of the American Physical Therapy Association. 24: 70-7. PMID 22207474 DOI: 10.1097/PEP.0b013e31823e0686  1
2012 Therrien M, Colloud F, Begon M. Effect of stroke rate on paddle tip path in kayaking Movement and Sports Sciences - Science Et Motricite. 75: 113-120. DOI: 10.1051/Sm/2011156  1
2011 Lavoie H, Therrien M. Cancer: A drug-resistant duo. Nature. 480: 329-30. PMID 22170679 DOI: 10.1038/480329a  1
2011 Bouffard V, Nantel J, Therrien M, Vendittoli PA, Lavigne M, Prince F. Center of Mass Compensation during Gait in Hip Arthroplasty Patients: Comparison between Large Diameter Head Total Hip Arthroplasty and Hip Resurfacing. Rehabilitation Research and Practice. 2011: 586412. PMID 22110976 DOI: 10.1155/2011/586412  1
2011 Ashton-Beaucage D, Therrien M. The exon junction complex: a splicing factor for long intron containing transcripts? Fly. 5: 224-33. PMID 21478676  1
2011 Udell CM, Rajakulendran T, Sicheri F, Therrien M. Mechanistic principles of RAF kinase signaling. Cellular and Molecular Life Sciences : Cmls. 68: 553-65. PMID 20820846 DOI: 10.1007/S00018-010-0520-6  1
2011 Buckley KE, Therrien MC, Mohr RM. Agronomic performance of barley cultivars in response to varying rates of swine slurry Canadian Journal of Plant Science. 91: 69-79. DOI: 10.4141/CJPS09032  1
2011 Arisz H, Therrien M, Burrell BC, LeBlanc MM. The potential effects of climate change on the vulnerability of roads and associated structures, Greater Sudbury, Ontario Proceedings, Annual Conference - Canadian Society For Civil Engineering. 4: 2985-2994.  1
2011 Ganberg G, Ayers J, Schurr N, Therrien M, Rousseau J. Representing context using the context for human and automation teams model Aaai Workshop - Technical Report. 20-25.  1
2011 Ashton-Beaucage D, Therrien M. The exon junction complex a splicing factor for long intron containing transcripts? Fly. 5: 1-10.  1
2010 Ashton-Beaucage D, Therrien M. [The greater RTK/RAS/ERK signalling pathway: how genetics has helped piece together a signalling network]. MéDecine Sciences : M/S. 26: 1067-73. PMID 21187046 DOI: 10.1051/medsci/201026121067  1
2010 Caron E, Ghosh S, Matsuoka Y, Ashton-Beaucage D, Therrien M, Lemieux S, Perreault C, Roux PP, Kitano H. A comprehensive map of the mTOR signaling network. Molecular Systems Biology. 6: 453. PMID 21179025 DOI: 10.1038/Msb.2010.108  1
2010 Ashton-Beaucage D, Udell CM, Lavoie H, Baril C, Lefrançois M, Chagnon P, Gendron P, Caron-Lizotte O, Bonneil E, Thibault P, Therrien M. The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila. Cell. 143: 251-62. PMID 20946983 DOI: 10.1016/J.Cell.2010.09.014  1
2010 Therrien ME, Collin CA. Spatial vision meets spatial cognition: examining the effect of visual blur on human visually guided route learning. Perception. 39: 1043-64. PMID 20942357 DOI: 10.1068/p5991  1
2010 Lavoie H, Therrien M. [It takes two RAFs to tango]. MéDecine Sciences : M/S. 26: 459-60. PMID 20510139 DOI: 10.1051/medsci/2010265459  1
2010 Lavigne M, Therrien M, Nantel J, Roy A, Prince F, Vendittoli PA. The John Charnley Award: The functional outcome of hip resurfacing and large-head THA is the same: a randomized, double-blind study. Clinical Orthopaedics and Related Research. 468: 326-36. PMID 19543863 DOI: 10.1007/S11999-009-0938-Z  1
2010 Buckley KE, Mohr RM, Therrien MC. Yield and quality of oat in response to varying rates of swine slurry Canadian Journal of Plant Science. 90: 645-653. DOI: 10.4141/CJPS09033  1
2010 Galinier J, Becquelin AM, Bordin G, Fontaine L, Fourmaux F, Ponce JR, Salzarulo P, Simonnot P, Therrien M, Zilli I. Anthropology of the night: Cross-disciplinary investigations Current Anthropology. 51: 819-847. DOI: 10.1086/653691  1
2010 Schurr N, Good R, Alexander A, Picciano P, Ganberg G, Therrien M, Beard BL, Holbrook J. A testbed for investigating task allocation strategies between air traffic controllers and automated agents Proceedings of the National Conference On Artificial Intelligence. 3: 1839-1845.  1
2009 Rajakulendran T, Sahmi M, Lefrançois M, Sicheri F, Therrien M. A dimerization-dependent mechanism drives RAF catalytic activation. Nature. 461: 542-5. PMID 19727074 DOI: 10.1038/Nature08314  1
2009 Lacoste M, Therrien M, Prince F. Stability of children with cerebral palsy in their wheelchair seating: perceptions of parents and therapists. Disability and Rehabilitation. Assistive Technology. 4: 143-50. PMID 19378209 DOI: 10.1080/17483100802362036  1
2009 Baril C, Sahmi M, Ashton-Beaucage D, Stronach B, Therrien M. The PP2C Alphabet is a negative regulator of stress-activated protein kinase signaling in Drosophila. Genetics. 181: 567-79. PMID 19064708 DOI: 10.1534/Genetics.108.096461  1
2009 Therrien MC. Registration of 'Desperado' six-row barley Journal of Plant Registrations. 3: 1-4. DOI: 10.3198/jpr2008.06.0349crc  1
2008 Taylor LT, Therrien ME. Inhibition of return for the discrimination of faces. Perception & Psychophysics. 70: 279-90. PMID 18372749 DOI: 10.3758/PP.70.2.279  1
2008 Rajakulendran T, Sahmi M, Kurinov I, Tyers M, Therrien M, Sicheri F. CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling. Proceedings of the National Academy of Sciences of the United States of America. 105: 2836-41. PMID 18287031 DOI: 10.1073/Pnas.0709705105  1
2008 Gruber M, Smith D, O'Neal C, Hennessy K, Therrien M. Quality improvement project to determine outpatient chemotherapy capacity and improve utilization. Journal of Nursing Care Quality. 23: 75-83; quiz 84-5. PMID 18281879 DOI: 10.1097/01.NCQ.0000303808.93994.59  1
2008 Therrien M. Democracy and recognition: Building research partnerships Diogenes. 55: 134-136+144. DOI: 10.1177/0392192108096838  1
2007 Clapéron A, Therrien M. KSR and CNK: two scaffolds regulating RAS-mediated RAF activation. Oncogene. 26: 3143-58. PMID 17496912 DOI: 10.1038/sj.onc.1210408  1
2007 Beta T, Naing SK, Nam S, Mpofu A, Therrien M. Antioxidant activity in relationship to phenolic content of diverse food barley genotypes Acs Symposium Series. 956: 242-254.  1
2006 Collin CA, Therrien M, Martin C, Rainville S. Spatial frequency thresholds for face recognition when comparison faces are filtered and unfiltered. Perception & Psychophysics. 68: 879-89. PMID 17153184 DOI: 10.3758/Bf03193351  1
2006 Lacoste M, Therrien M, Côté JN, Shrier I, Labelle H, Prince F. Assessment of seated postural control in children: comparison of a force platform versus a pressure mapping system. Archives of Physical Medicine and Rehabilitation. 87: 1623-9. PMID 17141643 DOI: 10.1016/J.Apmr.2006.08.344  1
2006 Douziech M, Sahmi M, Laberge G, Therrien M. A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila. Genes & Development. 20: 807-19. PMID 16600912 DOI: 10.1101/gad.1390406  1
2006 Baril C, Therrien M. Alphabet, a Ser/Thr phosphatase of the protein phosphatase 2C family, negatively regulates RAS/MAPK signaling in Drosophila. Developmental Biology. 294: 232-45. PMID 16600208 DOI: 10.1016/j.ydbio.2006.02.046  1
2006 Ames N, Rhymer C, Rossnagel B, Therrien M, Ryland D, Dua S, Ross K. Utilization of diverse hulless barley properties to maximize food product quality Cereal Foods World. 51: 23-28. DOI: 10.1094/CFW-51-0023  1
2005 Taylor TL, Therrien ME. Inhibition of return for faces. Perception & Psychophysics. 67: 1414-22. PMID 16555593 DOI: 10.3758/Bf03193646  1
2005 Laberge G, Douziech M, Therrien M. Src42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism. The Embo Journal. 24: 487-98. PMID 15660123 DOI: 10.1038/sj.emboj.7600558  1
2005 Therrien MC. Modelling systemic learning of complex events: A case study of forest fires International Journal of Emergency Management. 2: 203-217. DOI: 10.1504/IJEM.2005.007360  1
2004 Champagne MA, Capdeville R, Krailo M, Qu W, Peng B, Rosamilia M, Therrien M, Zoellner U, Blaney SM, Bernstein M. Imatinib mesylate (STI571) for treatment of children with Philadelphia chromosome-positive leukemia: results from a Children's Oncology Group phase 1 study. Blood. 104: 2655-60. PMID 15231574 DOI: 10.1182/Blood-2003-09-3032  1
2004 Tanguay GA, Therrien MC. PROTECTING CANADA AND THE U.S. AGAINST TERRORISM: A COMMON SECURITY PERIMETER? Research in Global Strategic Management. 10: 85-96. DOI: 10.1016/S1064-4857(04)10005-3  1
2004 Legge WG, Therrien MC, Tucker JR, Banik M, Tekauz A, Somers O, Savard ME, Rossnagel BC, Lefol E, Voth D, Zatorski T, Harvey BL, Scoles G. Progress in breeding for resistance to fusarium head blight in barley Canadian Journal of Plant Pathology. 26: 436-442.  1
2003 Douziech M, Roy F, Laberge G, Lefrançois M, Armengod AV, Therrien M. Bimodal regulation of RAF by CNK in Drosophila. The Embo Journal. 22: 5068-78. PMID 14517245 DOI: 10.1093/emboj/cdg506  1
2003 Soucier R, Silverman D, Abordo M, Jaagosild P, Abiose A, Madhusoodanan KP, Therrien M, Lippman N, Dalamagas H, Berns E. Propafenone versus ibutilide for post operative atrial fibrillation following cardiac surgery: neither strategy improves outcomes compared to rate control alone (the PIPAF study). Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 9: PI19-23. PMID 12640352  1
2002 Roy F, Therrien M. MAP kinase module: the Ksr connection. Current Biology : Cb. 12: R325-7. PMID 12007434 DOI: 10.1016/S0960-9822(02)00831-X  1
2002 Roy F, Laberge G, Douziech M, Ferland-McCollough D, Therrien M. KSR is a scaffold required for activation of the ERK/MAPK module. Genes & Development. 16: 427-38. PMID 11850406 DOI: 10.1101/gad.962902  1
2001 Therrien M. Did the principle of double effect justify the separation? The National Catholic Bioethics Quarterly. 1: 417-27. PMID 12866529  1
2000 Bernier S, Dubois DY, Therrien M, Lapointe J, Chênevert R. Synthesis of glutaminyl adenylate analogues that are inhibitors of glutaminyl-tRNA synthetase. Bioorganic & Medicinal Chemistry Letters. 10: 2441-4. PMID 11078196 DOI: 10.1016/S0960-894X(00)00478-9  1
2000 Therrien M, Morrison DK, Wong AM, Rubin GM. A genetic screen for modifiers of a kinase suppressor of Ras-dependent rough eye phenotype in Drosophila. Genetics. 156: 1231-42. PMID 11063697  1
1999 Therrien M, Wong AM, Kwan E, Rubin GM. Functional analysis of CNK in RAS signaling. Proceedings of the National Academy of Sciences of the United States of America. 96: 13259-63. PMID 10557308 DOI: 10.1073/Pnas.96.23.13259  1
1999 Cacace AM, Michaud NR, Therrien M, Mathes K, Copeland T, Rubin GM, Morrison DK. Identification of constitutive and ras-inducible phosphorylation sites of KSR: implications for 14-3-3 binding, mitogen-activated protein kinase binding, and KSR overexpression. Molecular and Cellular Biology. 19: 229-40. PMID 9858547 DOI: 10.1128/Mcb.19.1.229  1
1998 Therrien M, Wong AM, Rubin GM. CNK, a RAF-binding multidomain protein required for RAS signaling. Cell. 95: 343-53. PMID 9814705 DOI: 10.1016/S0092-8674(00)81766-3  1
1998 Krumholz HM, Philbin DM, Wang Y, Vaccarino V, Murillo JE, Therrien ML, Williams J, Radford MJ. Trends in the quality of care for Medicare beneficiaries admitted to the hospital with unstable angina. Journal of the American College of Cardiology. 31: 957-63. PMID 9561993 DOI: 10.1016/S0735-1097(98)00106-5  1
1998 Therrien MJ. Sécurité, espionnage et diplomatie: L'architecture des chancelleries canadiennes pendant la guerre froide (1946-1983) International Journal. 53: 419-438.  1
1998 Therrien MC, Grant CA. Effect of tillage management on yield performance in barley Canadian Journal of Plant Science. 78: 301-303.  1
1997 Rubin GM, Chang HC, Karim F, Laverty T, Michaud NR, Morrison DK, Rebay I, Tang A, Therrien M, Wassarman DA. Signal transduction downstream from Ras in Drosophila. Cold Spring Harbor Symposia On Quantitative Biology. 62: 347-52. PMID 9598368 DOI: 10.1101/Sqb.1997.062.01.041  1
1997 Michaud NR, Therrien M, Cacace A, Edsall LC, Spiegel S, Rubin GM, Morrison DK. KSR stimulates Raf-1 activity in a kinase-independent manner. Proceedings of the National Academy of Sciences of the United States of America. 94: 12792-6. PMID 9371754 DOI: 10.1073/pnas.94.24.12792  1
1997 Meehan TP, Radford MJ, Vaccarino LV, Gottlieb LD, McGovern-Hughes B, Herman MV, Revkin JH, Therrien ML, Petrillo MK, Krumholz HM. A collaborative project in Connecticut to improve the care of patients with acute myocardial infarction. Connecticut Medicine. 61: 147-55. PMID 9097486  1
1997 Dabrah TT, Harwood HJ, Huang LH, Jankovich ND, Kaneko T, Li JC, Lindsey S, Moshier PM, Subashi TA, Therrien M, Watts PC. CP-225,917 and CP-263,114, novel Ras farnesylation inhibitors from an unidentified fungus. I. Taxonomy, fermentation, isolation, and biochemical properties. The Journal of Antibiotics. 50: 1-7. PMID 9066758  1
1997 Wassarman DA, Therrien M. Ras1-Mediated Photoreceptor Development in Drosophila Advances in Developmental Biology (1992). 5: 1-41. DOI: 10.1016/S1566-3116(08)60034-1  1
1997 Liu YH, Rangarajan A, Gagnon D, Therrien M, Sinusas AJ, Wackers FJT, Zubal G. New methods for SPECT imaging and pre-reconstruction restoration Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 1230: 531-536.  1
1997 Therrien ML. Outcomes management what is it and how does it affect me? Journal of the Hoffman Heart Institute of Connecticut. 3: 6-8.  1
1997 Soucier R, Kosack C, Therrien M, Missri J. Acute myocardial infarction in women: An observational study in a large academic community hospital Journal of the Hoffman Heart Institute of Connecticut. 3: 2-5.  1
1996 Therrien M, Michaud NR, Rubin GM, Morrison DK. KSR modulates signal propagation within the MAPK cascade. Genes & Development. 10: 2684-95. PMID 8946910 DOI: 10.1101/Gad.10.21.2684  1
1996 Meehan TP, Radford MJ, Vaccarino LV, Gottlieb LD, McGovern-Hughes B, Herman MV, Revkin JH, Therrien ML, Petrillo MK, Krumholz HM. A collaborative project in Connecticut to improve the care of patients with acute myocardial infarction. The Joint Commission Journal On Quality Improvement. 22: 751-61. PMID 8937949 DOI: 10.1016/S1070-3241(16)30280-2  1
1996 Karim FD, Chang HC, Therrien M, Wassarman DA, Laverty T, Rubin GM. A screen for genes that function downstream of Ras1 during Drosophila eye development. Genetics. 143: 315-29. PMID 8722784  1
1996 Lamonerie T, Tremblay JJ, Lanctôt C, Therrien M, Gauthier Y, Drouin J. Ptx1, a bicoid-related homeo box transcription factor involved in transcription of the pro-opiomelanocortin gene. Genes & Development. 10: 1284-95. PMID 8675014 DOI: 10.1101/Gad.10.10.1284  1
1996 Wassarman DA, Solomon NM, Chang HC, Karim FD, Therrien M, Rubin GM. Protein phosphatase 2A positively and negatively regulates Ras1-mediated photoreceptor development in Drosophila. Genes & Development. 10: 272-8. PMID 8595878 DOI: 10.1101/Gad.10.3.272  1
1996 McCaughey WP, Therrien MC, Mabon R. Forage sorghum in southern Manitoba Canadian Journal of Plant Science. 76: 123-125.  1
1995 Therrien M, Chang HC, Solomon NM, Karim FD, Wassarman DA, Rubin GM. KSR, a novel protein kinase required for RAS signal transduction. Cell. 83: 879-88. PMID 8521512 DOI: 10.1016/0092-8674(95)90204-X  1
1995 Chang HC, Solomon NM, Wassarman DA, Karim FD, Therrien M, Rubin GM, Wolff T. phyllopod functions in the fate determination of a subset of photoreceptors in Drosophila. Cell. 80: 463-72. PMID 7888014 DOI: 10.1016/0092-8674(95)90497-2  1
1995 Wassarman DA, Therrien M, Rubin GM. The Ras signaling pathway in Drosophila. Current Opinion in Genetics & Development. 5: 44-50. PMID 7749324 DOI: 10.1016/S0959-437X(95)90052-7  1
1995 Therrien MC. Interorganizational networks and decision making in technological disasters Safety Science. 20: 101-113. DOI: 10.1016/0925-7535(94)00071-A  1
1995 Grant CA, Bailey LD, Therrien MC. The effect of N, P and KCl fertilizers on grain yield and Cd concentration of malting barley Fertilizer Research. 45: 153-161. DOI: 10.1007/BF00790665  1
1995 Narasimhalu P, Kong D, Choo TM, Ferguson T, Therrien MC, Ho KM, May KW, Jui P. Effects of environment and cultivar on total mixed-linkage beta-glucan content in eastern and western Canadian barleys (Hordeum vulgare L.) Canadian Journal of Plant Science. 75: 371-376.  1
1994 Zhang Z, King MW, Guidoin R, Therrien M, Pezolet M, Adnot A, Ukpabi P, Vantal MH. Morphological, physical and chemical evaluation of the Vascugraft arterial prosthesis: comparison of a novel polyurethane device with other microporous structures. Biomaterials. 15: 483-501. PMID 7918901 DOI: 10.1016/0142-9612(94)90014-0  1
1994 Zhang Z, King M, Guidoin R, Therrien M, Doillon C, Diehl-Jones WL, Huebner E. In vitro exposure of a novel polyesterurethane graft to enzymes: a study of the biostability of the Vascugraft arterial prosthesis. Biomaterials. 15: 1129-44. PMID 7893915 DOI: 10.1016/0142-9612(94)90233-X  1
1994 Fenrick R, Babinski K, McNicoll N, Therrien M, Drouin J, De Léan A. Cloning and functional expression of the bovine natriuretic peptide receptor-B (natriuretic factor R1c subtype. Molecular and Cellular Biochemistry. 137: 173-82. PMID 7845391 DOI: 10.1007/Bf00944079  1
1994 Chang HC, Karim FD, O'Neill EM, Rebay I, Solomon NM, Therrien M, Wassarman DA, Wolff T, Rubin GM. Ras signal transduction pathway in Drosophila eye development. Cold Spring Harbor Symposia On Quantitative Biology. 59: 147-53. PMID 7587064 DOI: 10.1101/Sqb.1994.059.01.018  1
1994 Kong D, Choo TM, Jui P, Ferguson T, Therrien MC, Ho KM, May KW, Narasimhalu P. Genetic variation and adaptation of 76 Canadian barley cultivars Canadian Journal of Plant Science. 74: 737-744.  1
1994 Therrien MC, Carmichael CA, Noll JS, Grant CA. Effect of fertilizer management, genotype, and environmental factors on some malting quality characteristics in barley Canadian Journal of Plant Science. 74: 545-547.  1
1993 Gagnon D, Pouliot N, Laperriere L, Therrien M, Olivier P. Maximum likelihood positioning in the scintillation camera using depth of interaction. Ieee Transactions On Medical Imaging. 12: 101-7. PMID 18218398 DOI: 10.1109/42.222673  1
1993 Therrien M, Drouin J. Molecular determinants for cell specificity and glucocorticoid repression of the proopiomelanocortin gene. Annals of the New York Academy of Sciences. 680: 663-71. PMID 8512237 DOI: 10.1111/J.1749-6632.1993.Tb19768.X  1
1993 Therrien M, Drouin J. Cell-specific helix-loop-helix factor required for pituitary expression of the pro-opiomelanocortin gene. Molecular and Cellular Biology. 13: 2342-53. PMID 8455616 DOI: 10.1128/MCB.13.4.2342  1
1993 Guidoin R, Maurel S, Chakfé N, How T, Zhang Z, Therrien M, Formichi M, Gosselin C. Expanded polytetrafluoroethylene arterial prostheses in humans: chemical analysis of 79 explanted specimens. Biomaterials. 14: 694-704. PMID 8399966  0.01
1992 Guidoin R, Therrien M, Rolland C, King M, Grandmaison JL, Kaliaguine S, Blais P, Pakdel H, Roy C. The polyurethane foam covering the Même breast prosthesis: a biomedical breakthrough or a biomaterial tar baby? Annals of Plastic Surgery. 28: 342-53. PMID 1596068 DOI: 10.1097/00000637-199204000-00009  1
1991 Therrien M, Drouin J. Pituitary pro-opiomelanocortin gene expression requires synergistic interactions of several regulatory elements. Molecular and Cellular Biology. 11: 3492-503. PMID 2046665 DOI: 10.1128/MCB.11.7.3492  1
1991 Nolfo E, Wright-Browne V, Therrien M, Ardolino A, Macinski Z. Plasmapheresis in a case of eosinophilia-myalgia syndrome with ascending polyneuropathy. Chest. 100: 584. PMID 1864154  1
1991 Fram DB, Missri J, Therrien ML, Chawla S. Assessment of Ebstein's anomaly and its surgical repair using transesophageal two-dimensional echocardiography and Doppler color flow mapping Echocardiography. 8: 367-372.  1
1990 Drouin J, Therrien M, Sun YL, Mullick A, Nemer M. Cell specificity and glucocorticoid repression of POMC gene transcription New Leads in Opioid Research: Proceedings of the International Narcotics Research Conference. Ics914. 109.  1
1989 Drouin J, Nemer M, Charron J, Gagner JP, Jeannotte L, Sun YL, Therrien M, Tremblay Y. Tissue-specific activity of the pro-opiomelanocortin (POMC) gene and repression by glucocorticoids. Genome / National Research Council Canada = GéNome / Conseil National De Recherches Canada. 31: 510-9. PMID 2698828 DOI: 10.1139/G89-099  1
1989 Therrien M, Guidoin R, Adnot A, Paynter R. Hydrophobic and fibrillar microporous polyetherurethane urea prosthesis: an ESCA study on the internal and external surfaces of explanted grafts. Biomaterials. 10: 517-20. PMID 2605285 DOI: 10.1016/0142-9612(89)90056-2  1
1988 Therrien ML. Streptokinase or TPA for acute myocardial infarction: Is one agent superior? Cardiovascular Reviews and Reports. 9: 55-64.  1
1987 Therrien ML, Moreno B, Korr KS, Heller GV. Acute myocardial infarction associated with prolonged sneezing. The American Journal of Cardiology. 59: 364-5. PMID 3812292  0.01
1977 Fine VK, Therrien ME. Empathy in the doctor-patient relationship: skill training for medical students. Journal of Medical Education. 52: 752-7. PMID 886588  1
1975 Kirk SA, Therrien ME. Community mental health myths and the fate of former hospitalized patients. Psychiatry. 38: 209-17. PMID 172927 DOI: 10.1080/00332747.1975.11023851  1
1974 Therrien M. The M.A.T. as a predictor of academic success among registered nurses enrolled in the B.Sc.N. programme Abstracts of Hospital Management Studies. 11: 12158 NU:57p.  1
1972 Taylor ML, Therrien M. GENTILLY - COMMISSIONING AND EARLY OPERATION Nuclear Engineering International. 17: 929-933.  1
1964 MASSOD MF, FRANEY RJ, THERRIEN ME, RIDEOUT PT, BABCOCK MT. LACTIC DEHYDROGENASE ACTIVITY OF URINE. AN EVALUATION OF THE SPECTROPHOTOMETRIC AND COLORIMETRIC METHODS. American Journal of Clinical Pathology. 42: 623-5. PMID 14239440  1
1964 MASSOD MF, FRANEY RJ, THERRIEN ME, RIDEOUT PT, BABCOCK MT. LACTIC DEHYDROGENASE ACTIVITY OF URINE. AN EVALUATION OF THE SPECTROPHOTOMETRIC AND COLORIMETRIC METHODS. Technical Bulletin of the Registry of Medical Technologists. 34: 177-9. PMID 14222336  1
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