Tom Neufeld - Publications


58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bjedov I, Cochemé HM, Foley A, Wieser D, Woodling NS, Castillo-Quan JI, Norvaisas P, Lujan C, Regan J, Toivonen JM, Murphy MP, Thornton J, Kinghorn KJ, Neufeld TP, Cabreiro F, et al. Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila. Plos Genetics. 16: e1009083. PMID 33253201 DOI: 10.1371/journal.pgen.1009083  0.56
2016 Mauvezin C, Neisch AL, Ayala CI, Kim J, Beltrame A, Braden CR, Gardner MK, Hays TS, Neufeld TP. Coordination of autophagosome-lysosome fusion and transport by a Klp98A-Rab14 complex. Journal of Cell Science. PMID 26763909 DOI: 10.1242/Jcs.175224  1
2015 Jin A, Neufeld TP, Choe J. Kibra and aPKC regulate starvation-induced autophagy in Drosophila. Biochemical and Biophysical Research Communications. PMID 26551466 DOI: 10.1016/J.Bbrc.2015.11.011  1
2015 Mauvezin C, Neufeld TP. Bafilomycin A1 disrupts autophagic flux by inhibiting both V-ATPase-dependent acidification and Ca-P60A/SERCA-dependent autophagosome-lysosome fusion. Autophagy. 11: 1437-8. PMID 26156798 DOI: 10.1080/15548627.2015.1066957  1
2015 Mauvezin C, Nagy P, Juhász G, Neufeld TP. Autophagosome-lysosome fusion is independent of V-ATPase-mediated acidification. Nature Communications. 6: 7007. PMID 25959678 DOI: 10.1038/Ncomms8007  1
2015 Kim J, Neufeld TP. Dietary sugar promotes systemic TOR activation in Drosophila through AKH-dependent selective secretion of Dilp3. Nature Communications. 6: 6846. PMID 25882208 DOI: 10.1038/Ncomms7846  1
2014 Mauvezin C, Ayala C, Braden CR, Kim J, Neufeld TP. Assays to monitor autophagy in Drosophila. Methods (San Diego, Calif.). 68: 134-9. PMID 24667416 DOI: 10.1016/J.Ymeth.2014.03.014  1
2013 Knævelsrud H, Søreng K, Raiborg C, Håberg K, Rasmuson F, Brech A, Liestøl K, Rusten TE, Stenmark H, Neufeld TP, Carlsson SR, Simonsen A. Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation. The Journal of Cell Biology. 202: 331-49. PMID 23878278 DOI: 10.1083/Jcb.201205129  1
2013 Russell RC, Tian Y, Yuan H, Park HW, Chang YY, Kim J, Kim H, Neufeld TP, Dillin A, Guan KL. ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase. Nature Cell Biology. 15: 741-50. PMID 23685627 DOI: 10.1038/Ncb2757  1
2012 Jimenez-Sanchez M, Menzies FM, Chang YY, Simecek N, Neufeld TP, Rubinsztein DC. The Hedgehog signalling pathway regulates autophagy. Nature Communications. 3: 1200. PMID 23149744 DOI: 10.1038/Ncomms2212  1
2012 Neufeld TP. Autophagy and cell growth--the yin and yang of nutrient responses. Journal of Cell Science. 125: 2359-68. PMID 22649254 DOI: 10.1242/Jcs.103333  1
2012 Dimitroff B, Howe K, Watson A, Campion B, Lee HG, Zhao N, O'Connor MB, Neufeld TP, Selleck SB. Diet and energy-sensing inputs affect TorC1-mediated axon misrouting but not TorC2-directed synapse growth in a Drosophila model of tuberous sclerosis. Plos One. 7: e30722. PMID 22319582 DOI: 10.1371/Journal.Pone.0030722  1
2010 Neufeld TP, Arsham AM. tRNA trafficking along the TOR pathway. Cell Cycle (Georgetown, Tex.). 9: 3146-7. PMID 20814229 DOI: 10.4161/Cc.9.16.12781  1
2010 Li L, Kim E, Yuan H, Inoki K, Goraksha-Hicks P, Schiesher RL, Neufeld TP, Guan KL. Regulation of mTORC1 by the Rab and Arf GTPases. The Journal of Biological Chemistry. 285: 19705-9. PMID 20457610 DOI: 10.1074/Jbc.C110.102483  1
2010 Chang YY, Neufeld TP. Autophagy takes flight in Drosophila. Febs Letters. 584: 1342-9. PMID 20079355 DOI: 10.1016/J.Febslet.2010.01.006  1
2010 Neufeld TP. TOR-dependent control of autophagy: biting the hand that feeds. Current Opinion in Cell Biology. 22: 157-68. PMID 20006481 DOI: 10.1016/J.Ceb.2009.11.005  1
2010 Neufeld TP. Cell-intrinsic functions and regulation of TOR signaling in Drosophila Enzymes. 28: 205-216. DOI: 10.1016/S1874-6047(10)28010-1  1
2009 Arsham AM, Neufeld TP. A genetic screen in Drosophila reveals novel cytoprotective functions of the autophagy-lysosome pathway. Plos One. 4: e6068. PMID 19562034 DOI: 10.1371/Journal.Pone.0006068  1
2009 Chang YY, Neufeld TP. An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation. Molecular Biology of the Cell. 20: 2004-14. PMID 19225150 DOI: 10.1091/Mbc.E08-12-1250  1
2009 Ling D, Song HJ, Garza D, Neufeld TP, Salvaterra PM. Abeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in Drosophila. Plos One. 4: e4201. PMID 19145255 DOI: 10.1371/Journal.Pone.0004201  1
2009 Chang YY, Juhász G, Goraksha-Hicks P, Arsham AM, Mallin DR, Muller LK, Neufeld TP. Nutrient-dependent regulation of autophagy through the target of rapamycin pathway. Biochemical Society Transactions. 37: 232-6. PMID 19143638 DOI: 10.1042/Bst0370232  1
2008 Neufeld TP. Genetic manipulation and monitoring of autophagy in Drosophila. Methods in Enzymology. 451: 653-67. PMID 19185744 DOI: 10.1016/S0076-6879(08)03236-9  1
2008 Kim E, Goraksha-Hicks P, Li L, Neufeld TP, Guan KL. Regulation of TORC1 by Rag GTPases in nutrient response. Nature Cell Biology. 10: 935-45. PMID 18604198 DOI: 10.1038/Ncb1753  1
2008 Meléndez A, Neufeld TP. The cell biology of autophagy in metazoans: a developing story. Development (Cambridge, England). 135: 2347-60. PMID 18567846 DOI: 10.1242/Dev.016105  1
2008 Juhász G, Hill JH, Yan Y, Sass M, Baehrecke EH, Backer JM, Neufeld TP. The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila. The Journal of Cell Biology. 181: 655-66. PMID 18474623 DOI: 10.1083/Jcb.200712051  1
2008 Juhasz G, Neufeld TP. Experimental control and characterization of autophagy in Drosophila. Methods in Molecular Biology (Clifton, N.J.). 445: 125-33. PMID 18425447 DOI: 10.1007/978-1-59745-157-4_8  1
2008 Neufeld TP, Baehrecke EH. Eating on the fly: function and regulation of autophagy during cell growth, survival and death in Drosophila. Autophagy. 4: 557-62. PMID 18319640 DOI: 10.4161/Auto.5782  1
2008 Juhász G, Neufeld TP. Drosophila Atg7: required for stress resistance, longevity and neuronal homeostasis, but not for metamorphosis. Autophagy. 4: 357-8. PMID 18216496 DOI: 10.4161/Auto.5572  1
2007 Juhász G, Erdi B, Sass M, Neufeld TP. Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila. Genes & Development. 21: 3061-6. PMID 18056421 DOI: 10.1101/Gad.1600707  1
2007 Neufeld TP. Contribution of Atg1-dependent autophagy to TOR-mediated cell growth and survival. Autophagy. 3: 477-9. PMID 17525525 DOI: 10.4161/Auto.4348  1
2007 Knox S, Ge H, Dimitroff BD, Ren Y, Howe KA, Arsham AM, Easterday MC, Neufeld TP, O'Connor MB, Selleck SB. Mechanisms of TSC-mediated control of synapse assembly and axon guidance. Plos One. 2: e375. PMID 17440611 DOI: 10.1371/Journal.Pone.0000375  1
2007 Juhász G, Puskás LG, Komonyi O, Erdi B, Maróy P, Neufeld TP, Sass M. Gene expression profiling identifies FKBP39 as an inhibitor of autophagy in larval Drosophila fat body. Cell Death and Differentiation. 14: 1181-90. PMID 17363962 DOI: 10.1038/Sj.Cdd.4402123  1
2007 Scott RC, Juhász G, Neufeld TP. Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death. Current Biology : Cb. 17: 1-11. PMID 17208179 DOI: 10.1016/J.Cub.2006.10.053  1
2007 Eskelinen EL, Deretic V, Neufeld T, Levine B, Cuervo AM. 4th International Symposium on Autophagy: exploiting the frontiers of autophagy research. Autophagy. 3: 166-73. PMID 17204840 DOI: 10.4161/Auto.3654  1
2007 Neufeld TP. TOR regulation: sorting out the answers. Cell Metabolism. 5: 3-5. PMID 17189200 DOI: 10.1016/J.Cmet.2006.12.008  1
2006 Arsham AM, Neufeld TP. Thinking globally and acting locally with TOR. Current Opinion in Cell Biology. 18: 589-97. PMID 17046229 DOI: 10.1016/J.Ceb.2006.09.005  1
2006 Hennig KM, Colombani J, Neufeld TP. TOR coordinates bulk and targeted endocytosis in the Drosophila melanogaster fat body to regulate cell growth. The Journal of Cell Biology. 173: 963-74. PMID 16785324 DOI: 10.1083/Jcb.200511140  1
2006 Juhasz G, Neufeld TP. Autophagy: a forty-year search for a missing membrane source. Plos Biology. 4: e36. PMID 16464128 DOI: 10.1371/Journal.Pbio.0040036  1
2006 Zhang Y, Billington CJ, Pan D, Neufeld TP. Drosophila target of rapamycin kinase functions as a multimer. Genetics. 172: 355-62. PMID 16219781 DOI: 10.1534/Genetics.105.051979  1
2005 Cygnar KD, Gao X, Pan D, Neufeld TP. The phosphatase subunit tap42 functions independently of target of rapamycin to regulate cell division and survival in Drosophila. Genetics. 170: 733-40. PMID 15802506 DOI: 10.1534/Genetics.104.039909  1
2004 Scott RC, Schuldiner O, Neufeld TP. Role and regulation of starvation-induced autophagy in the Drosophila fat body. Developmental Cell. 7: 167-78. PMID 15296714 DOI: 10.1016/J.Devcel.2004.07.009  1
2004 Neufeld TP. Genetic analysis of TOR signaling in Drosophila. Current Topics in Microbiology and Immunology. 279: 139-52. PMID 14560956 DOI: 10.1007/978-3-642-18930-2_9  1
2003 Neufeld TP. Body building: regulation of shape and size by PI3K/TOR signaling during development. Mechanisms of Development. 120: 1283-96. PMID 14623438 DOI: 10.1016/J.Mod.2003.07.003  1
2003 Neufeld TP. Shrinkage control: regulation of insulin-mediated growth by FOXO transcription factors. Journal of Biology. 2: 18. PMID 12974982 DOI: 10.1186/1475-4924-2-18  1
2002 Neufeld TP, Hariharan IK. Regulation of growth and cell proliferation during eye development. Results and Problems in Cell Differentiation. 37: 107-33. PMID 25707072 DOI: 10.1007/978-3-540-45398-7_8  1
2002 Hennig KM, Neufeld TP. Inhibition of cellular growth and proliferation by dTOR overexpression in Drosophila. Genesis (New York, N.Y. : 2000). 34: 107-10. PMID 12324961 DOI: 10.1002/Gene.10139  1
2001 Tang AH, Neufeld TP, Rubin GM, Müller HA. Transcriptional regulation of cytoskeletal functions and segmentation by a novel maternal pair-rule gene, lilliputian. Development (Cambridge, England). 128: 801-13. PMID 11171404  1
2000 Zhang H, Stallock JP, Ng JC, Reinhard C, Neufeld TP. Regulation of cellular growth by the Drosophila target of rapamycin dTOR. Genes & Development. 14: 2712-24. PMID 11069888 DOI: 10.1101/Gad.835000  1
2000 Gao X, Neufeld TP, Pan D. Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways. Developmental Biology. 221: 404-18. PMID 10790335 DOI: 10.1006/Dbio.2000.9680  1
1999 Weinkove D, Neufeld TP, Twardzik T, Waterfield MD, Leevers SJ. Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor. Current Biology : Cb. 9: 1019-29. PMID 10508611 DOI: 10.1016/S0960-9822(99)80450-3  1
1998 Neufeld TP, Edgar BA. Connections between growth and the cell cycle. Current Opinion in Cell Biology. 10: 784-90. PMID 9914170 DOI: 10.1016/S0955-0674(98)80122-1  1
1998 Neufeld TP, de la Cruz AF, Johnston LA, Edgar BA. Coordination of growth and cell division in the Drosophila wing. Cell. 93: 1183-93. PMID 9657151 DOI: 10.1016/S0092-8674(00)81462-2  1
1998 Neufeld TP, Tang AH, Rubin GM. A genetic screen to identify components of the sina signaling pathway in Drosophila eye development. Genetics. 148: 277-86. PMID 9475739  1
1997 Tang AH, Neufeld TP, Kwan E, Rubin GM. PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism. Cell. 90: 459-67. PMID 9267026 DOI: 10.1016/S0092-8674(00)80506-1  1
1994 Neufeld TP, Rubin GM. The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins. Cell. 77: 371-9. PMID 8181057 DOI: 10.1016/0092-8674(94)90152-X  1
1994 Carthew RW, Neufeld TP, Rubin GM. Identification of genes that interact with the sina gene in Drosophila eye development. Proceedings of the National Academy of Sciences of the United States of America. 91: 11689-93. PMID 7972125 DOI: 10.1073/Pnas.91.24.11689  1
1991 Neufeld TP, Carthew RW, Rubin GM. Evolution of gene position: chromosomal arrangement and sequence comparison of the Drosophila melanogaster and Drosophila virilis sina and Rh4 genes. Proceedings of the National Academy of Sciences of the United States of America. 88: 10203-7. PMID 1946441 DOI: 10.1073/pnas.88.22.10203  1
1991 Staskus KA, Retzel EF, Lewis ED, Silsby JL, Sheila Cyr ST, Rank JM, Wietgrefe SW, Haase AT, Cook R, Fast D, Geiser PT, Harty JT, Kong SH, Lahti CJ, Neufeld TP, et al. Isolation of replication-competent molecular clones of visna virus Virology. 181: 228-240. PMID 1847257 DOI: 10.1016/0042-6822(91)90488-W  1
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