Manfred Frasch - Publications


85 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Frasch M. Dedifferentiation, Redifferentiation, and Transdifferentiation of Striated Muscles During Regeneration and Development Current Topics in Developmental Biology. DOI: 10.1016/bs.ctdb.2015.12.005  1
2015 Schmitt-Engel C, Schultheis D, Schwirz J, Ströhlein N, Troelenberg N, Majumdar U, Dao VA, Grossmann D, Richter T, Tech M, Dönitz J, Gerischer L, Theis M, Schild I, Trauner J, ... ... Frasch M, et al. The iBeetle large-scale RNAi screen reveals gene functions for insect development and physiology. Nature Communications. 6: 7822. PMID 26215380 DOI: 10.1038/ncomms8822  1
2015 Schaub C, März J, Reim I, Frasch M. Org-1-dependent lineage reprogramming generates the ventral longitudinal musculature of the Drosophila heart. Current Biology : Cb. 25: 488-94. PMID 25660543 DOI: 10.1016/j.cub.2014.12.029  1
2014 Boukhatmi H, Schaub C, Bataillé L, Reim I, Frendo JL, Frasch M, Vincent A. An Org-1-Tup transcriptional cascade reveals different types of alary muscles connecting internal organs in Drosophila. Development (Cambridge, England). 141: 3761-71. PMID 25209244 DOI: 10.1242/dev.111005  1
2014 Hollfelder D, Frasch M, Reim I. Distinct functions of the laminin β LN domain and collagen IV during cardiac extracellular matrix formation and stabilization of alary muscle attachments revealed by EMS mutagenesis in Drosophila. Bmc Developmental Biology. 14: 26. PMID 24935095 DOI: 10.1186/1471-213X-14-26  1
2013 Schaub C, Frasch M. Org-1 is required for the diversification of circular visceral muscle founder cells and normal midgut morphogenesis. Developmental Biology. 376: 245-59. PMID 23380635 DOI: 10.1016/j.ydbio.2013.01.022  1
2013 Jin H, Stojnic R, Adryan B, Ozdemir A, Stathopoulos A, Frasch M. Genome-wide screens for in vivo Tinman binding sites identify cardiac enhancers with diverse functional architectures. Plos Genetics. 9: e1003195. PMID 23326246 DOI: 10.1371/journal.pgen.1003195  1
2012 Reim I, Hollfelder D, Ismat A, Frasch M. The FGF8-related signals Pyramus and Thisbe promote pathfinding, substrate adhesion, and survival of migrating longitudinal gut muscle founder cells. Developmental Biology. 368: 28-43. PMID 22609944 DOI: 10.1016/j.ydbio.2012.05.010  1
2012 Schaub C, Nagaso H, Jin H, Frasch M. Org-1, the Drosophila ortholog of Tbx1, is a direct activator of known identity genes during muscle specification. Development (Cambridge, England). 139: 1001-12. PMID 22318630 DOI: 10.1242/dev.073890  1
2011 Schönbauer C, Distler J, Jährling N, Radolf M, Dodt HU, Frasch M, Schnorrer F. Spalt mediates an evolutionarily conserved switch to fibrillar muscle fate in insects. Nature. 479: 406-9. PMID 22094701 DOI: 10.1038/nature10559  1
2010 Müller D, Jagla T, Bodart LM, Jährling N, Dodt HU, Jagla K, Frasch M. Regulation and functions of the lms homeobox gene during development of embryonic lateral transverse muscles and direct flight muscles in Drosophila. Plos One. 5: e14323. PMID 21179520 DOI: 10.1371/journal.pone.0014323  1
2010 Ismat A, Schaub C, Reim I, Kirchner K, Schultheis D, Frasch M. HLH54F is required for the specification and migration of longitudinal gut muscle founders from the caudal mesoderm of Drosophila. Development (Cambridge, England). 137: 3107-17. PMID 20736287 DOI: 10.1242/dev.046573  1
2010 Inaki M, Shinza-Kameda M, Ismat A, Frasch M, Nose A. Drosophila Tey represses transcription of the repulsive cue Toll and generates neuromuscular target specificity. Development (Cambridge, England). 137: 2139-46. PMID 20504957 DOI: 10.1242/dev.046672  1
2010 Reim I, Frasch M. Genetic and genomic dissection of cardiogenesis in the Drosophila model. Pediatric Cardiology. 31: 325-34. PMID 20033682 DOI: 10.1007/s00246-009-9612-1  1
2010 Bodmer R, Frasch M. Development and Aging of the Drosophila Heart Heart Development and Regeneration. 47-86. DOI: 10.1016/B978-0-12-381332-9.00002-5  1
2008 Frasch M. A matter of timing: microRNA-controlled temporal identities in worms and flies. Genes & Development. 22: 1572-6. PMID 18559473 DOI: 10.1101/gad.1690608  1
2007 Nguyen HT, Voza F, Ezzeddine N, Frasch M. Drosophila mind bomb2 is required for maintaining muscle integrity and survival. The Journal of Cell Biology. 179: 219-27. PMID 17954605 DOI: 10.1083/jcb.200708135  1
2007 Lo PC, Zaffran S, Sénatore S, Frasch M. The Drosophila Hand gene is required for remodeling of the developing adult heart and midgut during metamorphosis. Developmental Biology. 311: 287-96. PMID 17904115 DOI: 10.1016/j.ydbio.2007.08.024  1
2007 Goltsev Y, Fuse N, Frasch M, Zinzen RP, Lanzaro G, Levine M. Evolution of the dorsal-ventral patterning network in the mosquito, Anopheles gambiae. Development (Cambridge, England). 134: 2415-24. PMID 17522157 DOI: 10.1242/dev.02863  1
2006 Zaffran S, Reim I, Qian L, Lo PC, Bodmer R, Frasch M. Cardioblast-intrinsic Tinman activity controls proper diversification and differentiation of myocardial cells in Drosophila. Development (Cambridge, England). 133: 4073-83. PMID 16987868 DOI: 10.1242/dev.02586  1
2006 Nguyen HT, Frasch M. MicroRNAs in muscle differentiation: lessons from Drosophila and beyond. Current Opinion in Genetics & Development. 16: 533-9. PMID 16919443 DOI: 10.1016/j.gde.2006.08.010  1
2005 Reim I, Frasch M. The Dorsocross T-box genes are key components of the regulatory network controlling early cardiogenesis in Drosophila. Development (Cambridge, England). 132: 4911-25. PMID 16221729 DOI: 10.1242/dev.02077  1
2005 Zaffran S, Frasch M. The homeodomain of Tinman mediates homo- and heterodimerization of NK proteins. Biochemical and Biophysical Research Communications. 334: 361-9. PMID 16004970 DOI: 10.1016/j.bbrc.2005.06.090  1
2005 Reim I, Mohler JP, Frasch M. Tbx20-related genes, mid and H15, are required for tinman expression, proper patterning, and normal differentiation of cardioblasts in Drosophila. Mechanisms of Development. 122: 1056-69. PMID 15922573 DOI: 10.1016/j.mod.2005.04.006  1
2005 Wang J, Tao Y, Reim I, Gajewski K, Frasch M, Schulz RA. Expression, regulation, and requirement of the toll transmembrane protein during dorsal vessel formation in Drosophila melanogaster. Molecular and Cellular Biology. 25: 4200-10. PMID 15870289 DOI: 10.1128/MCB.25.10.4200-4210.2005  1
2005 Lee HH, Frasch M. Nuclear integration of positive Dpp signals, antagonistic Wg inputs and mesodermal competence factors during Drosophila visceral mesoderm induction. Development (Cambridge, England). 132: 1429-42. PMID 15750188 DOI: 10.1242/dev.01687  1
2004 Stathopoulos A, Tam B, Ronshaugen M, Frasch M, Levine M. pyramus and thisbe: FGF genes that pattern the mesoderm of Drosophila embryos. Genes & Development. 18: 687-99. PMID 15075295 DOI: 10.1101/gad.1166404  1
2004 Lee HH, Frasch M. Survey of forkhead domain encoding genes in the Drosophila genome: Classification and embryonic expression patterns. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 229: 357-66. PMID 14745961 DOI: 10.1002/dvdy.10443  1
2003 Lee HH, Norris A, Weiss JB, Frasch M. Jelly belly protein activates the receptor tyrosine kinase Alk to specify visceral muscle pioneers. Nature. 425: 507-12. PMID 14523446 DOI: 10.1038/nature01916  1
2003 Lo PC, Frasch M. Establishing A-P polarity in the embryonic heart tube: a conserved function of Hox genes in Drosophila and vertebrates? Trends in Cardiovascular Medicine. 13: 182-7. PMID 12837580 DOI: 10.1016/S1050-1738(03)00074-4  1
2003 Reim I, Lee HH, Frasch M. The T-box-encoding Dorsocross genes function in amnioserosa development and the patterning of the dorsolateral germ band downstream of Dpp. Development (Cambridge, England). 130: 3187-204. PMID 12783790  1
2002 Zaffran S, Xu X, Lo PC, Lee HH, Frasch M. Cardiogenesis in the Drosophila model: control mechanisms during early induction and diversification of cardiac progenitors. Cold Spring Harbor Symposia On Quantitative Biology. 67: 1-12. PMID 12858517 DOI: 10.1101/sqb.2002.67.1  1
2002 Lo PC, Skeath JB, Gajewski K, Schulz RA, Frasch M. Homeotic genes autonomously specify the anteroposterior subdivision of the Drosophila dorsal vessel into aorta and heart. Developmental Biology. 251: 307-19. PMID 12435360 DOI: 10.1006/dbio.2002.0839  1
2002 Zaffran S, Frasch M. Early signals in cardiac development. Circulation Research. 91: 457-69. PMID 12242263 DOI: 10.1161/01.RES.0000034152.74523.A8  1
2002 Zaffran S, Frasch M. The beta 3 tubulin gene is a direct target of bagpipe and biniou in the visceral mesoderm of Drosophila. Mechanisms of Development. 114: 85-93. PMID 12175492 DOI: 10.1016/S0925-4773(02)00063-1  1
2001 Knirr S, Frasch M. Molecular integration of inductive and mesoderm-intrinsic inputs governs even-skipped enhancer activity in a subset of pericardial and dorsal muscle progenitors. Developmental Biology. 238: 13-26. PMID 11783990 DOI: 10.1006/dbio.2001.0397  1
2001 Zaffran S, Küchler A, Lee HH, Frasch M. biniou (FoxF), a central component in a regulatory network controlling visceral mesoderm development and midgut morphogenesis in Drosophila. Genes & Development. 15: 2900-15. PMID 11691840 DOI: 10.1101/gad.917101  1
2001 Lo PC, Frasch M. A role for the COUP-TF-related gene seven-up in the diversification of cardioblast identities in the dorsal vessel of Drosophila. Mechanisms of Development. 104: 49-60. PMID 11404079 DOI: 10.1016/S0925-4773(01)00361-6  1
2001 Jagla K, Bellard M, Frasch M. A cluster of Drosophila homeobox genes involved in mesoderm differentiation programs. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 23: 125-33. PMID 11169585 DOI: 10.1002/1521-1878(200102)23:2<125::AID-BIES1019>3.0.CO;2-C  1
2000 Wang W, Lo P, Frasch M, Lufkin T. Hmx: an evolutionary conserved homeobox gene family expressed in the developing nervous system in mice and Drosophila. Mechanisms of Development. 99: 123-37. PMID 11091080 DOI: 10.1016/S0925-4773(00)00488-3  1
2000 Lee HH, Frasch M. Wingless effects mesoderm patterning and ectoderm segmentation events via induction of its downstream target sloppy paired. Development (Cambridge, England). 127: 5497-508. PMID 11076769  1
2000 Read D, Butte MJ, Dernburg AF, Frasch M, Kornberg TB. Functional studies of the BTB domain in the Drosophila GAGA and Mod(mdg4) proteins. Nucleic Acids Research. 28: 3864-70. PMID 11024164  1
2000 Frasch M, Leptin M. Mergers and acquisitions: unequal partnerships in Drosophila myoblast fusion. Cell. 102: 127-9. PMID 10943831  1
2000 Zaffran S, Das G, Frasch M. The NK-2 homeobox gene scarecrow (scro) is expressed in pharynx, ventral nerve cord and brain of Drosophila embryos. Mechanisms of Development. 94: 237-41. PMID 10842079 DOI: 10.1016/S0925-4773(00)00298-7  1
2000 Zaffran S, Frasch M. Barbu: an E(spl) m4/m(alpha)-related gene that antagonizes Notch signaling and is required for the establishment of ommatidial polarity. Development (Cambridge, England). 127: 1115-30. PMID 10662650  1
1999 Frasch M. Controls in patterning and diversification of somatic muscles during Drosophila embryogenesis. Current Opinion in Genetics & Development. 9: 522-9. PMID 10508697 DOI: 10.1016/S0959-437X(99)00014-3  1
1999 Knirr S, Azpiazu N, Frasch M. The role of the NK-homeobox gene slouch (S59) in somatic muscle patterning. Development (Cambridge, England). 126: 4525-35. PMID 10498687  1
1999 Lo PC, Frasch M. Sequence and expression of myoglianin, a novel Drosophila gene of the TGF-beta superfamily. Mechanisms of Development. 86: 171-5. PMID 10446278 DOI: 10.1016/S0925-4773(99)00108-2  1
1999 Frasch M. Intersecting signalling and transcriptional pathways in Drosophila heart specification. Seminars in Cell & Developmental Biology. 10: 61-71. PMID 10355030 DOI: 10.1006/scdb.1998.0279  1
1998 Yin Z, Frasch M. Regulation and function of tinman during dorsal mesoderm induction and heart specification in Drosophila. Developmental Genetics. 22: 187-200. PMID 9621427 DOI: 10.1002/(SICI)1520-6408(1998)22:3<187::AID-DVG2>3.0.CO;2-2  1
1998 Lo PC, Frasch M. bagpipe-Dependent expression of vimar, a novel Armadillo-repeats gene, in Drosophila visceral mesoderm. Mechanisms of Development. 72: 65-75. PMID 9533953 DOI: 10.1016/S0925-4773(98)00016-1  1
1997 Yin Z, Xu XL, Frasch M. Regulation of the twist target gene tinman by modular cis-regulatory elements during early mesoderm development. Development (Cambridge, England). 124: 4971-82. PMID 9362473  1
1997 Lo PC, Frasch M. A novel KH-domain protein mediates cell adhesion processes in Drosophila. Developmental Biology. 190: 241-56. PMID 9344542 DOI: 10.1006/dbio.1997.8699  1
1997 Jagla K, Frasch M, Jagla T, Dretzen G, Bellard F, Bellard M. ladybird, a new component of the cardiogenic pathway in Drosophila required for diversification of heart precursors. Development (Cambridge, England). 124: 3471-9. PMID 9342040  1
1997 Tribioli C, Frasch M, Lufkin T. Bapx1: an evolutionary conserved homologue of the Drosophila bagpipe homeobox gene is expressed in splanchnic mesoderm and the embryonic skeleton. Mechanisms of Development. 65: 145-62. PMID 9256352 DOI: 10.1016/S0925-4773(97)00067-1  1
1996 Azpiazu N, Lawrence PA, Vincent JP, Frasch M. Segmentation and specification of the Drosophila mesoderm. Genes & Development. 10: 3183-94. PMID 8985186  1
1996 D'Alessio M, Frasch M. msh may play a conserved role in dorsoventral patterning of the neuroectoderm and mesoderm. Mechanisms of Development. 58: 217-31. PMID 8887329 DOI: 10.1016/S0925-4773(96)00583-7  1
1995 Küssel P, Frasch M. Pendulin, a Drosophila protein with cell cycle-dependent nuclear localization, is required for normal cell proliferation. The Journal of Cell Biology. 129: 1491-507. PMID 7790350 DOI: 10.1083/jcb.129.6.1491  1
1995 Frasch M, Chen X, Lufkin T. Evolutionary-conserved enhancers direct region-specific expression of the murine Hoxa-1 and Hoxa-2 loci in both mice and Drosophila. Development (Cambridge, England). 121: 957-74. PMID 7743939  1
1995 Frasch M. Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo. Nature. 374: 464-7. PMID 7700357 DOI: 10.1038/374464a0  1
1995 Maggert K, Levine M, Frasch M. The somatic-visceral subdivision of the embryonic mesoderm is initiated by dorsal gradient thresholds in Drosophila. Development (Cambridge, England). 121: 2107-16. PMID 7635056  1
1995 Fernandez R, Tabarini D, Azpiazu N, Frasch M, Schlessinger J. The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential. The Embo Journal. 14: 3373-84. PMID 7628438  1
1995 Küssel P, Frasch M. Yeast Srp1, a nuclear protein related to Drosophila and mouse pendulin, is required for normal migration, division, and integrity of nuclei during mitosis. Molecular & General Genetics : Mgg. 248: 351-63. PMID 7565597 DOI: 10.1007/BF02191602  1
1993 Azpiazu N, Frasch M. tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila. Genes & Development. 7: 1325-40. PMID 8101173  1
1993 Bate M, Rushton E, Frasch M. A dual requirement for neurogenic genes in Drosophila myogenesis. Development (Cambridge, England). Supplement. 149-61. PMID 8049469  1
1992 Paterson BM, Shirakata M, Nakamura S, Dechesne C, Walldorf U, Eldridge J, Dübendorfer A, Frasch M, Gehring WJ. Isolation and functional comparison of Dmyd, the Drosophila homologue of the vertebrate myogenic determination genes, with CMD1. Symposia of the Society For Experimental Biology. 46: 89-109. PMID 1285197  1
1991 Ohtsubo M, Yoshida T, Seino H, Nishitani H, Clark KL, Sprague GF, Frasch M, Nishimoto T. Mutation of the hamster cell cycle gene RCC1 is complemented by the homologous genes of Drosophila and S.cerevisiae. The Embo Journal. 10: 1265-73. PMID 2022190  1
1991 Frasch M. The maternally expressed Drosophila gene encoding the chromatin-binding protein BJ1 is a homolog of the vertebrate gene Regulator of Chromatin Condensation, RCC1. The Embo Journal. 10: 1225-36. PMID 2022188  1
1991 van Lohuizen M, Frasch M, Wientjens E, Berns A. Sequence similarity between the mammalian bmi-1 proto-oncogene and the Drosophila regulatory genes Psc and Su(z)2. Nature. 353: 353-5. PMID 1922340 DOI: 10.1038/353353a0  1
1991 Paterson BM, Walldorf U, Eldridge J, Dübendorfer A, Frasch M, Gehring WJ. The Drosophila homologue of vertebrate myogenic-determination genes encodes a transiently expressed nuclear protein marking primary myogenic cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 3782-6. PMID 1902570  1
1991 Champlin DT, Frasch M, Saumweber H, Lis JT. Characterization of a Drosophila protein associated with boundaries of transcriptionally active chromatin. Genes & Development. 5: 1611-21. PMID 1885003  1
1990 Saumweber H, Frasch M, Korge G. Two puff-specific proteins bind within the 2.5 kb upstream region of the Drosophila melanogaster Sgs-4 gene Chromosoma. 99: 52-60. PMID 2160364 DOI: 10.1007/BF01737289  1
1990 Dohrmann C, Azpiazu N, Frasch M. A new Drosophila homeo box gene is expressed in mesodermal precursor cells of distinct muscles during embryogenesis Genes and Development. 4: 2098-2111. PMID 1980118  1
1989 Frasch M, Saumweber H. Two proteins from Drosophila nuclei are bound to chromatin and are detected in a series of puffs on polytene chromosomes Chromosoma. 97: 272-281. PMID 2495915 DOI: 10.1007/BF00371966  1
1989 Frasch M, Wenzel W, Hess D. The nucleotide sequences of nuclear 5S rRNA genes and spacer regions of Petunia hybrida Nucleic Acids Research. 17: 2857. DOI: 10.1093/nar/17.7.2857  1
1988 Frasch M, Paddy M, Saumweber H. Developmental and mitotic behaviour of two novel groups of nuclear envelope antigens of Drosophila melanogaster Journal of Cell Science. 90: Pt 2/-. PMID 3149954  1
1988 Whitfield WG, Millar SE, Saumweber H, Frasch M, Glover DM. Cloning of a gene encoding an antigen associated with the centrosome in Drosophila Journal of Cell Science. 89: Pt 4/-. PMID 3143740  1
1988 Frasch M, Warrior R, Tugwood J, Levine M. Molecular analysis of even-skipped mutants in Drosophila development. Genes & Development. 2: 1824-38. PMID 2907321 DOI: 10.1101/GAD.2.12B.1824  1
1988 Ruder FJ, Frasch M, Büsen W. Specific radioimmunoprecipitation of histone H2A antigens by protein A conjugated sepharose Experientia. 44: 347-348. PMID 2452094 DOI: 10.1007/BF01961278  1
1987 Ruder FJ, Frasch M, Mettenleiter TC, Büsen W. Appearance of two maternally directed histone H2A variants precedes zygotic ubiquitination of H2A in early embryogenesis of Sciara coprophila (Diptera) Developmental Biology. 122: 568-576. PMID 22272423 DOI: 10.1016/0012-1606(87)90320-4  1
1987 Frasch M, Levine M. Complementary patterns of even-skipped and fushi tarazu expression involve their differential regulation by a common set of segmentation genes in Drosophila. Genes & Development. 1: 981-95. PMID 2892761 DOI: 10.1101/GAD.1.9.981  1
1987 Rushlow C, Frasch M, Doyle H, Levine M. Maternal regulation of zerknüllt: a homoeobox gene controlling differentiation of dorsal tissues in Drosophila. Nature. 330: 583-6. PMID 2891036 DOI: 10.1038/330583a0  1
1987 Frasch M, Hoey T, Rushlow C, Doyle H, Levine M. Characterization and localization of the even-skipped protein of Drosophila. The Embo Journal. 6: 749-59. PMID 2884106  1
1986 Frasch M, Glover DM, Saumweber H. Nuclear antigens follow different pathways into daughter nuclei during mitosis in early Drosophila embryos Journal of Cell Science. 82: 155-172. PMID 3098744  1
1983 Risau W, Symmons P, Saumweber H, Frasch M. Nonpackaging and packaging proteins of hnRNA in Drosophila melanogaster Cell. 33: 529-541. PMID 6407757 DOI: 10.1016/0092-8674(83)90434-8  1
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