Year |
Citation |
Score |
2022 |
Krzystek TJ, White JA, Rathnayake R, Thurston L, Hoffmar-Glennon H, Li Y, Gunawardena S. HTT (huntingtin) and RAB7 co-migrate retrogradely on a signaling LAMP1-containing late endosome during axonal injury. Autophagy. PMID 36048753 DOI: 10.1080/15548627.2022.2119351 |
0.379 |
|
2020 |
White JA, Krzystek TJ, Hoffmar-Glennon H, Thant C, Zimmerman K, Iacobucci G, Vail J, Thurston L, Rahman S, Gunawardena S. Excess Rab4 rescues synaptic and behavioral dysfunction caused by defective HTT-Rab4 axonal transport in Huntington's disease. Acta Neuropathologica Communications. 8: 97. PMID 32611447 DOI: 10.1186/S40478-020-00964-Z |
0.535 |
|
2020 |
Banerjee R, White JA, Gunawardena S. In Vivo Visualization of Moving Synaptic Cargo Complexes within Drosophila Larval Segmental Axons. Methods in Molecular Biology (Clifton, N.J.). 2143: 293-300. PMID 32524488 DOI: 10.1007/978-1-0716-0585-1_21 |
0.379 |
|
2019 |
Anderson EN, Hirpa D, Zheng KH, Banerjee R, Gunawardena S. The Non-amyloidal Component Region of α-Synuclein Is Important for α-Synuclein Transport Within Axons. Frontiers in Cellular Neuroscience. 13: 540. PMID 32038170 DOI: 10.3389/fncel.2019.00540 |
0.405 |
|
2019 |
Hansen T, Thant C, White JA, Banerjee R, Thuamsang B, Gunawardena S. Excess active P13K rescues huntingtin-mediated neuronal cell death but has no effect on axonal transport defects. Apoptosis : An International Journal On Programmed Cell Death. PMID 30725352 DOI: 10.1007/s10495-019-01520-4 |
0.513 |
|
2018 |
Banerjee R, Rudloff Z, Naylor C, Yu M, Gunawardena S. The Presenilin loop region is essential for Glycogen synthase kinase 3 beta mediated functions on motor proteins during axonal transport. Human Molecular Genetics. PMID 29790963 DOI: 10.1093/hmg/ddy190 |
0.505 |
|
2018 |
Gunawardena S, Banerjee R. P4-261: THE LOOP REGION OF PRESENILIN (PS) REGULATES GSK-3β-MEDIATED EFFECTS ON MOTOR PROTEINS DURING AXONAL TRANSPORT Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.07.083 |
0.474 |
|
2017 |
Iacobucci GJ, Gunawardena S. Ethanol stimulates the in vivo axonal movement of neuropeptide dense core vesicles in Drosophila motor neurons. Journal of Neurochemistry. PMID 28960313 DOI: 10.1111/Jnc.14230 |
0.396 |
|
2017 |
Gunawardena S, Banerjee R. THE LOOP REGION OF PRESENILIN (PS) IS ESSENTIAL FOR GLYCOGEN SYNTHASE KINASE-3β (GSK-3β)-MEDIATED AXONAL TRANSPORT Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.1370 |
0.395 |
|
2016 |
White JA, Banerjee R, Gunawardena S. Axonal Transport and Neurodegeneration: How Marine Drugs Can Be Used for the Development of Therapeutics. Marine Drugs. 14. PMID 27213408 DOI: 10.3390/md14050102 |
0.533 |
|
2016 |
Xu W, Weissmiller AM, White JA, Fang F, Wang X, Wu Y, Pearn ML, Zhao X, Sawa M, Chen S, Gunawardena S, Ding J, Mobley WC, Wu C. Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration. The Journal of Clinical Investigation. PMID 27064279 DOI: 10.1172/Jci82409 |
0.449 |
|
2015 |
White JA, Anderson E, Zimmerman K, Zheng KH, Rouhani R, Gunawardena S. Huntingtin differentially regulates the axonal transport of a sub-set of Rab-containing vesicles in vivo. Human Molecular Genetics. PMID 26450517 DOI: 10.1093/hmg/ddv415 |
0.549 |
|
2014 |
Anderson EN, White JA, Gunawardena S. Axonal transport and neurodegenerative disease: vesicle-motor complex formation and their regulation. Degenerative Neurological and Neuromuscular Disease. 4: 29-47. PMID 32669899 DOI: 10.2147/DNND.S57502 |
0.429 |
|
2014 |
Kang MJ, Hansen TJ, Mickiewicz M, Kaczynski TJ, Fye S, Gunawardena S. Disruption of axonal transport perturbs bone morphogenetic protein (BMP)--signaling and contributes to synaptic abnormalities in two neurodegenerative diseases. Plos One. 9: e104617. PMID 25127478 DOI: 10.1371/journal.pone.0104617 |
0.49 |
|
2014 |
Ehaideb SN, Iyengar A, Ueda A, Iacobucci GJ, Cranston C, Bassuk AG, Gubb D, Axelrod JD, Gunawardena S, Wu CF, Manak JR. prickle modulates microtubule polarity and axonal transport to ameliorate seizures in flies. Proceedings of the National Academy of Sciences of the United States of America. 111: 11187-92. PMID 25024231 DOI: 10.1073/Pnas.1403357111 |
0.41 |
|
2014 |
Iacobucci GJ, Rahman NA, Valtueña AA, Nayak TK, Gunawardena S. Spatial and temporal characteristics of normal and perturbed vesicle transport. Plos One. 9: e97237. PMID 24878565 DOI: 10.1371/Journal.Pone.0097237 |
0.483 |
|
2014 |
Dolma K, Iacobucci GJ, Hong Zheng K, Shandilya J, Toska E, White JA, Spina E, Gunawardena S. Presenilin influences glycogen synthase kinase-3 β (GSK-3β) for kinesin-1 and dynein function during axonal transport. Human Molecular Genetics. 23: 1121-33. PMID 24105467 DOI: 10.1093/Hmg/Ddt505 |
0.503 |
|
2014 |
Gunawardena S. Presenilin And Gsk3B Control Kinesin-1 And Dynein Functions During App Vesicle Transport Alzheimers & Dementia. 10: 171. DOI: 10.1016/J.Jalz.2014.04.178 |
0.401 |
|
2013 |
Gunawardena S, Yang G, Goldstein LS. Presenilin controls kinesin-1 and dynein function during APP-vesicle transport in vivo. Human Molecular Genetics. 22: 3828-43. PMID 23710041 DOI: 10.1093/Hmg/Ddt237 |
0.62 |
|
2013 |
Gunawardena S. Nanoparticles in the brain: a potential therapeutic system targeted to an early defect observed in many neurodegenerative diseases. Pharmaceutical Research. 30: 2459-74. PMID 23625095 DOI: 10.1007/s11095-013-1037-0 |
0.401 |
|
2012 |
Gunawardena S. Developing nanotherapies for neurodegenerative diseases: ORMOSIL and its potential in axonal transport. Therapeutic Delivery. 3: 1189-98. PMID 23116011 DOI: 10.4155/tde.12.101 |
0.518 |
|
2012 |
Power D, Srinivasan S, Gunawardena S. In-vivo evidence for the disruption of Rab11 vesicle transport by loss of huntingtin. Neuroreport. 23: 970-7. PMID 23032403 DOI: 10.1097/WNR.0b013e328359d990 |
0.478 |
|
2012 |
Gunawardena S. Presenilin controls kinesin-1 and dynein activity in axonal transport Alzheimers & Dementia. 8: 436. DOI: 10.1016/J.Jalz.2012.05.1163 |
0.491 |
|
2011 |
Gunawardena S. Presenilin and gamma-secretase control kinesin-1 and dynein activity in axonal transport Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.259 |
0.486 |
|
2010 |
Kuznicki ML, Gunawardena S. In vivo visualization of synaptic vesicles within Drosophila larval segmental axons. Journal of Visualized Experiments : Jove. PMID 20972416 DOI: 10.3791/2151 |
0.504 |
|
2010 |
Fye S, Dolma K, Kang MJ, Gunawardena S. Visualization of larval segmental nerves in 3(rd) instar Drosophila larval preparations. Journal of Visualized Experiments : Jove. PMID 20972400 DOI: 10.3791/2128 |
0.366 |
|
2010 |
Falzone TL, Gunawardena S, McCleary D, Reis GF, Goldstein LS. Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies. Human Molecular Genetics. 19: 4399-408. PMID 20817925 DOI: 10.1093/Hmg/Ddq363 |
0.595 |
|
2008 |
Stokin GB, Almenar-Queralt A, Gunawardena S, Rodrigues EM, Falzone T, Kim J, Lillo C, Mount SL, Roberts EA, McGowan E, Williams DS, Goldstein LS. Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides. Human Molecular Genetics. 17: 3474-86. PMID 18694898 DOI: 10.1093/Hmg/Ddn240 |
0.578 |
|
2006 |
Gunawardena S, Goldstein L. O4-02-02 Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.301 |
0.358 |
|
2005 |
Gunawardena S, Goldstein LS. Polyglutamine diseases and transport problems: deadly traffic jams on neuronal highways. Archives of Neurology. 62: 46-51. PMID 15642849 DOI: 10.1001/archneur.62.1.46 |
0.578 |
|
2004 |
Gunawardena S, Goldstein LS. Cargo-carrying motor vehicles on the neuronal highway: transport pathways and neurodegenerative disease. Journal of Neurobiology. 58: 258-71. PMID 14704957 DOI: 10.1002/neu.10319 |
0.61 |
|
2003 |
Gunawardena S, Her LS, Brusch RG, Laymon RA, Niesman IR, Gordesky-Gold B, Sintasath L, Bonini NM, Goldstein LS. Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron. 40: 25-40. PMID 14527431 DOI: 10.1016/S0896-6273(03)00594-4 |
0.616 |
|
2001 |
Gunawardena S, Goldstein LS. Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila. Neuron. 32: 389-401. PMID 11709151 DOI: 10.1016/S0896-6273(01)00496-2 |
0.628 |
|
2000 |
Goldstein LS, Gunawardena S. Flying through the drosophila cytoskeletal genome. The Journal of Cell Biology. 150: F63-8. PMID 10908588 DOI: 10.1083/Jcb.150.2.F63 |
0.409 |
|
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