David Robbins - Publications

Affiliations: 
 

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Broadus MR, Chen TW, Neitzel LR, Ng VH, Jodoin JN, Lee LA, Salic A, Robbins DJ, Capobianco AJ, Patton JG, Huppert SS, Lee E. Identification of a Paralog-Specific Notch1 Intracellular Domain Degron. Cell Reports. PMID 27210761 DOI: 10.1016/J.Celrep.2016.04.070  1
2016 Astudillo L, da Silva TG, Wang Z, Han X, Jin K, VanWye J, Zhu X, Weaver KL, Oashi T, Lopes PE, Orton D, Neitzel LR, Lee E, Landgraf R, Robbins DJ, et al. The small molecule IMR-1 inhibits the Notch transcriptional activation complex to suppress tumorigenesis. Cancer Research. PMID 27197169 DOI: 10.1158/0008-5472.Can-16-0061  1
2016 Green BB, Karagas MR, Punshon T, Jackson BP, Robbins DJ, Houseman EA, Marsit CJ. Epigenome-Wide Assessment of DNA Methylation in the Placenta and Arsenic Exposure in the New Hampshire Birth Cohort Study (USA). Environmental Health Perspectives. PMID 26771251 DOI: 10.1289/Ehp.1510437  1
2015 Long J, Winterbottom E, Robbins DJ. Sonic Hedgehog: a lipid speciated hormone? Oncotarget. 6: 19340-1. PMID 26305721 DOI: 10.18632/Oncotarget.4969  1
2015 Winterbottom EF, Fei DL, Koestler DC, Giambelli C, Wika E, Capobianco AJ, Lee E, Marsit CJ, Karagas MR, Robbins DJ. GLI3 Links Environmental Arsenic Exposure and Human Fetal Growth. Ebiomedicine. 2: 536-43. PMID 26288817 DOI: 10.1016/J.Ebiom.2015.04.019  1
2015 Farzan SF, Robbins DJ. Quantitative Immunoblotting of Endogenous Hedgehog Pathway Components. Methods in Molecular Biology (Clifton, N.J.). 1322: 93-104. PMID 26179042 DOI: 10.1007/978-1-4939-2772-2_9  1
2015 Penas C, Govek EE, Fang Y, Ramachandran V, Daniel M, Wang W, Maloof ME, Rahaim RJ, Bibian M, Kawauchi D, Finkelstein D, Han JL, Long J, Li B, Robbins DJ, et al. Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis. Cell Reports. 11: 249-60. PMID 25843713 DOI: 10.1016/J.Celrep.2015.03.016  1
2015 Long J, Tokhunts R, Old WM, Houel S, Rodgriguez-Blanco J, Singh S, Schilling N, Capobianco AJ, Ahn NG, Robbins DJ. Identification of a family of fatty-acid-speciated sonic hedgehog proteins, whose members display differential biological properties. Cell Reports. 10: 1280-7. PMID 25732819 DOI: 10.1016/J.Celrep.2015.01.058  1
2015 Lindley LE, Curtis KM, Sanchez-Mejias A, Rieger ME, Robbins DJ, Briegel KJ. The WNT-controlled transcriptional regulator LBH is required for mammary stem cell expansion and maintenance of the basal lineage. Development (Cambridge, England). 142: 893-904. PMID 25655704 DOI: 10.1242/Dev.110403  1
2015 Allen BK, Stathias V, Maloof ME, Vidovic D, Winterbottom EF, Capobianco AJ, Clarke J, Schurer S, Robbins DJ, Ayad NG. Epigenetic pathways and glioblastoma treatment: insights from signaling cascades. Journal of Cellular Biochemistry. 116: 351-63. PMID 25290986 DOI: 10.1002/Jcb.24990  1
2015 Patel A, Burton DG, Halvorsen K, Balkan W, Reiner T, Perez-Stable C, Cohen A, Munoz A, Giribaldi MG, Singh S, Robbins DJ, Nguyen DM, Rai P. MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways. Oncogene. 34: 2586-96. PMID 25023700 DOI: 10.1038/Onc.2014.195  1
2015 Allen BK, Stathias V, Maloof ME, Vidovic D, Winterbottom EF, Capobianco AJ, Clarke J, Schurer S, Robbins DJ, Ayad NG. Editor's Choice: Epigenetic Pathways and Glioblastoma Treatment: Insights from Signaling Cascades Journal of Cellular Biochemistry. 116: iii. DOI: 10.1002/Jcb.25034  1
2014 Long J, Li B, Rodriguez-Blanco J, Pastori C, Volmar CH, Wahlestedt C, Capobianco A, Bai F, Pei XH, Ayad NG, Robbins DJ. The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers. The Journal of Biological Chemistry. 289: 35494-502. PMID 25355313 DOI: 10.1074/Jbc.M114.595348  1
2014 Bai F, Chan HL, Scott A, Smith MD, Fan C, Herschkowitz JI, Perou CM, Livingstone AS, Robbins DJ, Capobianco AJ, Pei XH. BRCA1 suppresses epithelial-to-mesenchymal transition and stem cell dedifferentiation during mammary and tumor development. Cancer Research. 74: 6161-72. PMID 25239453 DOI: 10.1158/0008-5472.Can-14-1119  1
2014 Nadeau KC, Li Z, Farzan S, Koestler D, Robbins D, Fei DL, Malipatlolla M, Maecker H, Enelow R, Korrick S, Karagas MR. In utero arsenic exposure and fetal immune repertoire in a US pregnancy cohort. Clinical Immunology (Orlando, Fla.). 155: 188-97. PMID 25229165 DOI: 10.1016/J.Clim.2014.09.004  1
2014 Wang Z, Da Silva TG, Jin K, Han X, Ranganathan P, Zhu X, Sanchez-Mejias A, Bai F, Li B, Fei DL, Weaver K, Carpio RV, Moscowitz AE, Koshenkov VP, Sanchez L, ... ... Robbins DJ, et al. Notch signaling drives stemness and tumorigenicity of esophageal adenocarcinoma. Cancer Research. 74: 6364-74. PMID 25164006 DOI: 10.1158/0008-5472.Can-14-2051  1
2014 Weaver KL, Alves-Guerra MC, Jin K, Wang Z, Han X, Ranganathan P, Zhu X, DaSilva T, Liu W, Ratti F, Demarest RM, Tzimas C, Rice M, Vasquez-Del Carpio R, Dahmane N, ... Robbins DJ, et al. NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis. Cancer Research. 74: 4741-51. PMID 25038227 DOI: 10.1158/0008-5472.Can-14-1547  1
2014 Li B, Flaveny CA, Giambelli C, Fei DL, Han L, Hang BI, Bai F, Pei XH, Nose V, Burlingame O, Capobianco AJ, Orton D, Lee E, Robbins DJ. Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis. Plos One. 9: e101969. PMID 25003333 DOI: 10.1371/Journal.Pone.0101969  1
2014 Li B, Fei DL, Flaveny CA, Dahmane N, Baubet V, Wang Z, Bai F, Pei XH, Rodriguez-Blanco J, Hang B, Orton D, Han L, Wang B, Capobianco AJ, Lee E, ... Robbins DJ, et al. Pyrvinium attenuates Hedgehog signaling downstream of smoothened. Cancer Research. 74: 4811-21. PMID 24994715 DOI: 10.1158/0008-5472.Can-14-0317  1
2014 Sverrisson EF, Zens MS, Fei DL, Andrews A, Schned A, Robbins D, Kelsey KT, Li H, DiRenzo J, Karagas MR, Seigne JD. Clinicopathological correlates of Gli1 expression in a population-based cohort of patients with newly diagnosed bladder cancer. Urologic Oncology. 32: 539-45. PMID 24856810 DOI: 10.1016/J.Urolonc.2014.03.006  1
2014 Busch AM, Galimberti F, Nehls KE, Roengvoraphoj M, Sekula D, Li B, Guo Y, Direnzo J, Fiering SN, Spinella MJ, Robbins DJ, Memoli VA, Freemantle SJ, Dmitrovsky E. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched. Cancer Biology & Therapy. 15: 463-72. PMID 24496080 DOI: 10.4161/Cbt.27821  1
2014 You M, Varona-Santos J, Singh S, Robbins DJ, Savaraj N, Nguyen DM. Targeting of the Hedgehog signal transduction pathway suppresses survival of malignant pleural mesothelioma cells in vitro. The Journal of Thoracic and Cardiovascular Surgery. 147: 508-16. PMID 24094913 DOI: 10.1016/J.Jtcvs.2013.08.035  1
2013 Srivastava RK, Li C, Chaudhary SC, Ballestas ME, Elmets CA, Robbins DJ, Matalon S, Deshane JS, Afaq F, Bickers DR, Athar M. Unfolded protein response (UPR) signaling regulates arsenic trioxide-mediated macrophage innate immune function disruption. Toxicology and Applied Pharmacology. 272: 879-87. PMID 23954561 DOI: 10.1016/J.Taap.2013.08.004  1
2013 Fei DL, Koestler DC, Li Z, Giambelli C, Sanchez-Mejias A, Gosse JA, Marsit CJ, Karagas MR, Robbins DJ. Association between In Utero arsenic exposure, placental gene expression, and infant birth weight: a US birth cohort study. Environmental Health : a Global Access Science Source. 12: 58. PMID 23866971 DOI: 10.1186/1476-069X-12-58  1
2013 Rodriguez-Blanco J, Schilling NS, Tokhunts R, Giambelli C, Long J, Liang Fei D, Singh S, Black KE, Wang Z, Galimberti F, Bejarano PA, Elliot S, Glassberg MK, Nguyen DM, Lockwood WW, ... ... Robbins DJ, et al. The hedgehog processing pathway is required for NSCLC growth and survival. Oncogene. 32: 2335-45. PMID 22733134 DOI: 10.1038/Onc.2012.243  1
2012 Robbins DJ, Fei DL, Riobo NA. The Hedgehog signal transduction network. Science Signaling. 5: re6. PMID 23074268 DOI: 10.1126/Scisignal.2002906  1
2012 Galimberti F, Busch AM, Chinyengetere F, Ma T, Sekula D, Memoli VA, Dragnev KH, Liu F, Johnson KC, Guo Y, Freemantle SJ, Andrew AS, Greninger P, Robbins DJ, Settleman J, et al. Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations. International Journal of Oncology. 41: 1751-61. PMID 22923130 DOI: 10.3892/Ijo.2012.1599  1
2012 Fei DL, Sanchez-Mejias A, Wang Z, Flaveny C, Long J, Singh S, Rodriguez-Blanco J, Tokhunts R, Giambelli C, Briegel KJ, Schulz WA, Gandolfi AJ, Karagas M, Zimmers TA, Jorda M, ... ... Robbins DJ, et al. Hedgehog signaling regulates bladder cancer growth and tumorigenicity. Cancer Research. 72: 4449-58. PMID 22815529 DOI: 10.1158/0008-5472.Can-11-4123  1
2012 Saeed AM, Toonkel R, Glassberg MK, Nguyen D, Hu JJ, Zimmers TA, Robbins DJ, Koniaris LG, Lally BE. The influence of Hispanic ethnicity on nonsmall cell lung cancer histology and patient survival: an analysis of the Survival, Epidemiology, and End Results database. Cancer. 118: 4495-501. PMID 22528551 DOI: 10.1002/Cncr.26686  1
2012 Hang BI, Thorne CA, Robbins DJ, Huppert SS, Lee LA, Lee E. Screening for small molecule inhibitors of embryonic pathways: sometimes you gotta crack a few eggs. Bioorganic & Medicinal Chemistry. 20: 1869-77. PMID 22261025 DOI: 10.1016/J.Bmc.2011.12.044  1
2011 Thorne CA, Lafleur B, Lewis M, Hanson AJ, Jernigan KK, Weaver DC, Huppert KA, Chen TW, Wichaidit C, Cselenyi CS, Tahinci E, Meyers KC, Waskow E, Orton D, Salic A, ... ... Robbins DJ, et al. A biochemical screen for identification of small-molecule regulators of the Wnt pathway using Xenopus egg extracts. Journal of Biomolecular Screening. 16: 995-1006. PMID 21859680 DOI: 10.1177/1087057111416657  1
2011 Singh S, Wang Z, Liang Fei D, Black KE, Goetz JA, Tokhunts R, Giambelli C, Rodriguez-Blanco J, Long J, Lee E, Briegel KJ, Bejarano PA, Dmitrovsky E, Capobianco AJ, Robbins DJ. Hedgehog-producing cancer cells respond to and require autocrine Hedgehog activity. Cancer Research. 71: 4454-63. PMID 21565978 DOI: 10.1158/0008-5472.Can-10-2313  1
2011 Vasquez-Del Carpio R, Kaplan FM, Weaver KL, VanWye JD, Alves-Guerra MC, Robbins DJ, Capobianco AJ. Assembly of a Notch transcriptional activation complex requires multimerization. Molecular and Cellular Biology. 31: 1396-408. PMID 21245387 DOI: 10.1128/Mcb.00360-10  1
2010 Xiao C, Ogle SA, Schumacher MA, Schilling N, Tokhunts RA, Orr-Asman MA, Miller ML, Robbins DJ, Hollande F, Zavros Y. Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G1252-65. PMID 20847300 DOI: 10.1152/Ajpgi.00512.2009  1
2010 Fei DL, Li H, Kozul CD, Black KE, Singh S, Gosse JA, DiRenzo J, Martin KA, Wang B, Hamilton JW, Karagas MR, Robbins DJ. Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors. Cancer Research. 70: 1981-8. PMID 20179202 DOI: 10.1158/0008-5472.Can-09-2898  1
2010 Farzan SF, Ogden SK, Robbins DJ. Quantitative insight into models of Hedgehog signal transduction Fly. 4: 141-144. PMID 20081354 DOI: 10.4161/Fly.4.2.10927  1
2010 Tokhunts R, Singh S, Chu T, D'Angelo G, Baubet V, Goetz JA, Huang Z, Yuan Z, Ascano M, Zavros Y, Thérond PP, Kunes S, Dahmane N, Robbins DJ. The full-length unprocessed hedgehog protein is an active signaling molecule. The Journal of Biological Chemistry. 285: 2562-8. PMID 19920144 DOI: 10.1074/Jbc.M109.078626  1
2009 Farzan SF, Stegman MA, Ogden SK, Ascano M, Black KE, Tacchelly O, Robbins DJ. A quantification of pathway components supports a novel model of Hedgehog signal transduction. The Journal of Biological Chemistry. 284: 28874-84. PMID 19717563 DOI: 10.1074/Jbc.M109.041608  1
2009 Singh S, Tokhunts R, Baubet V, Goetz JA, Huang ZJ, Schilling NS, Black KE, MacKenzie TA, Dahmane N, Robbins DJ. Sonic hedgehog mutations identified in holoprosencephaly patients can act in a dominant negative manner. Human Genetics. 125: 95-103. PMID 19057928 DOI: 10.1007/S00439-008-0599-0  1
2008 Ogden SK, Fei DL, Schilling NS, Ahmed YF, Hwa J, Robbins DJ. G protein Galphai functions immediately downstream of Smoothened in Hedgehog signalling. Nature. 456: 967-70. PMID 18987629 DOI: 10.1038/Nature07459  1
2008 Farzan SF, Ascano M, Ogden SK, Sanial M, Brigui A, Plessis A, Robbins DJ. Costal2 functions as a kinesin-like protein in the hedgehog signal transduction pathway. Current Biology : Cb. 18: 1215-20. PMID 18691888 DOI: 10.1016/J.Cub.2008.07.026  1
2008 Li N, Singh S, Cherukuri P, Li H, Yuan Z, Ellisen LW, Wang B, Robbins D, DiRenzo J. Reciprocal intraepithelial interactions between TP63 and hedgehog signaling regulate quiescence and activation of progenitor elaboration by mammary stem cells. Stem Cells (Dayton, Ohio). 26: 1253-64. PMID 18292212 DOI: 10.1634/Stemcells.2007-0691  1
2008 Farzan SF, Singh S, Schilling NS, Robbins DJ. The adventures of sonic hedgehog in development and repair. III. Hedgehog processing and biological activity. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G844-9. PMID 18239057 DOI: 10.1152/ajpgi.00564.2007  1
2007 Stegman M, Robbins D. Biochemical fractionation of Drosophila cells. Methods in Molecular Biology (Clifton, N.J.). 397: 203-13. PMID 18025722 DOI: 10.1007/978-1-59745-516-9_14  1
2007 Robbins DJ, Hebrok M. Hedgehogs: la dolce vita. Workshop on Hedgehog-Gli Signaling in Cancer and Stem Cells. Embo Reports. 8: 451-5. PMID 17431408 DOI: 10.1038/Sj.Embor.7400959  1
2007 Yuan Z, Goetz JA, Singh S, Ogden SK, Petty WJ, Black CC, Memoli VA, Dmitrovsky E, Robbins DJ. Frequent requirement of hedgehog signaling in non-small cell lung carcinoma. Oncogene. 26: 1046-55. PMID 16909105 DOI: 10.1038/Sj.Onc.1209860  1
2006 Ogden SK, Casso DJ, Ascano M, Yore MM, Kornberg TB, Robbins DJ. Smoothened regulates activator and repressor functions of Hedgehog signaling via two distinct mechanisms. The Journal of Biological Chemistry. 281: 7237-43. PMID 16423832 DOI: 10.1074/Jbc.M510169200  1
2006 Goetz JA, Singh S, Suber LM, Kull FJ, Robbins DJ. A highly conserved amino-terminal region of sonic hedgehog is required for the formation of its freely diffusible multimeric form. The Journal of Biological Chemistry. 281: 4087-93. PMID 16339763 DOI: 10.1074/Jbc.M511427200  1
2005 Bell SM, Schreiner CM, Goetz JA, Robbins DJ, Scott WJ. Shh signaling in limb bud ectoderm: potential role in teratogen-induced postaxial ectrodactyly. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 233: 313-25. PMID 15858818 DOI: 10.1002/dvdy.20409  1
2005 Scott WJ, Schreiner CM, Goetz JA, Robbins D, Bell SM. Cadmium-induced postaxial forelimb ectrodactyly: association with altered sonic hedgehog signaling. Reproductive Toxicology (Elmsford, N.Y.). 19: 479-85. PMID 15749261 DOI: 10.1016/j.reprotox.2004.11.013  1
2004 Ascano M, Robbins DJ. An intramolecular association between two domains of the protein kinase Fused is necessary for Hedgehog signaling. Molecular and Cellular Biology. 24: 10397-405. PMID 15542847 DOI: 10.1128/Mcb.24.23.10397-10405.2004  1
2004 Ogden SK, Ascano M, Stegman MA, Robbins DJ. Regulation of Hedgehog signaling: a complex story. Biochemical Pharmacology. 67: 805-14. PMID 15104233 DOI: 10.1016/J.Bcp.2004.01.002  1
2004 Tsonis PA, Vergara MN, Spence JR, Madhavan M, Kramer EL, Call MK, Santiago WG, Vallance JE, Robbins DJ, Del Rio-Tsonis K. A novel role of the hedgehog pathway in lens regeneration. Developmental Biology. 267: 450-61. PMID 15013805 DOI: 10.1016/J.Ydbio.2003.12.005  1
2004 Stegman MA, Goetz JA, Ascano M, Ogden SK, Nybakken KE, Robbins DJ. The Kinesin-related protein Costal2 associates with membranes in a Hedgehog-sensitive, Smoothened-independent manner. The Journal of Biological Chemistry. 279: 7064-71. PMID 14645371 DOI: 10.1074/Jbc.M311794200  1
2003 Ogden SK, Ascano M, Stegman MA, Suber LM, Hooper JE, Robbins DJ. Identification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2. Current Biology : Cb. 13: 1998-2003. PMID 14614827 DOI: 10.1016/J.Cub.2003.10.004  1
2003 Krebs O, Schreiner CM, Scott WJ, Bell SM, Robbins DJ, Goetz JA, Alt H, Hawes N, Wolf E, Favor J. Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud. Development (Cambridge, England). 130: 6037-47. PMID 14597572 DOI: 10.1242/Dev.00861  1
2002 Jeffries S, Robbins DJ, Capobianco AJ. Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line. Molecular and Cellular Biology. 22: 3927-41. PMID 11997524 DOI: 10.1128/MCB.22.11.3927-3941.2002  1
2002 Nybakken KE, Turck CW, Robbins DJ, Bishop JM. Hedgehog-stimulated phosphorylation of the kinesin-related protein Costal2 is mediated by the serine/threonine kinase fused. The Journal of Biological Chemistry. 277: 24638-47. PMID 11934882 DOI: 10.1074/jbc.M110730200  1
2002 Ascano M, Nybakken KE, Sosinski J, Stegman MA, Robbins DJ. The carboxyl-terminal domain of the protein kinase fused can function as a dominant inhibitor of hedgehog signaling. Molecular and Cellular Biology. 22: 1555-66. PMID 11839821 DOI: 10.1128/Mcb.22.5.1555-1566.2002  1
2002 Goetz JA, Suber LM, Zeng X, Robbins DJ. Sonic Hedgehog as a mediator of long-range signaling. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 24: 157-65. PMID 11835280 DOI: 10.1002/bies.10056  1
2001 Zeng X, Goetz JA, Suber LM, Scott WJ, Schreiner CM, Robbins DJ. A freely diffusible form of Sonic hedgehog mediates long-range signalling. Nature. 411: 716-20. PMID 11395778 DOI: 10.1038/35079648  1
2000 Stegman MA, Vallance JE, Elangovan G, Sosinski J, Cheng Y, Robbins DJ. Identification of a tetrameric hedgehog signaling complex. The Journal of Biological Chemistry. 275: 21809-12. PMID 10825151 DOI: 10.1074/jbc.C000043200  1
1997 Robbins DJ, Nybakken KE, Kobayashi R, Sisson JC, Bishop JM, Thérond PP. Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2. Cell. 90: 225-34. PMID 9244297 DOI: 10.1016/S0092-8674(00)80331-1  1
1996 Cobb MH, Xu S, Cheng M, Ebert D, Robbins D, Goldsmith E, Robinson M. Structural analysis of the MAP kinase ERK2 and studies of MAP kinase regulatory pathways. Advances in Pharmacology (San Diego, Calif.). 36: 49-65. PMID 8783554 DOI: 10.1016/S1054-3589(08)60576-1  1
1996 Xu S, Robbins DJ, Christerson LB, English JM, Vanderbilt CA, Cobb MH. Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain. Proceedings of the National Academy of Sciences of the United States of America. 93: 5291-5. PMID 8643568 DOI: 10.1073/pnas.93.11.5291  1
1995 Xu S, Robbins D, Frost J, Dang A, Lange-Carter C, Cobb MH. MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 92: 6808-12. PMID 7624324 DOI: 10.1073/pnas.92.15.6808  1
1995 Marcus S, Polverino A, Chang E, Robbins D, Cobb MH, Wigler MH. Shk1, a homolog of the Saccharomyces cerevisiae Ste20 and mammalian p65PAK protein kinases, is a component of a Ras/Cdc42 signaling module in the fission yeast Schizosaccharomyces pombe. Proceedings of the National Academy of Sciences of the United States of America. 92: 6180-4. PMID 7597098 DOI: 10.1073/Pnas.92.13.6180  1
1994 Zhang F, Strand A, Robbins D, Cobb MH, Goldsmith EJ. Atomic structure of the MAP kinase ERK2 at 2.3 A resolution. Nature. 367: 704-11. PMID 8107865 DOI: 10.1038/367704A0  1
1994 Robbins DJ, Zhen E, Cheng M, Xu S, Ebert D, Cobb MH. MAP kinases ERK1 and ERK2: pleiotropic enzymes in a ubiquitous signaling network. Advances in Cancer Research. 63: 93-116. PMID 8036991  1
1994 Cobb MH, Xu S, Hepler JE, Hutchison M, Frost J, Robbins DJ. Regulation of the MAP kinase cascade. Cellular & Molecular Biology Research. 40: 253-6. PMID 7874203  1
1994 Cobb MH, Hepler JE, Cheng M, Robbins D. The mitogen-activated protein kinases, ERK1 and ERK2. Seminars in Cancer Biology. 5: 261-8. PMID 7803762  1
1993 Robbins DJ, Zhen E, Owaki H, Vanderbilt CA, Ebert D, Geppert TD, Cobb MH. Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro. The Journal of Biological Chemistry. 268: 5097-106. PMID 8444886  1
1993 Zhang F, Robbins DJ, Cobb MH, Goldsmith EJ. Crystallization and preliminary X-ray studies of extracellular signal-regulated kinase-2/MAP kinase with an incorporated His-tag. Journal of Molecular Biology. 233: 550-2. PMID 8411162 DOI: 10.1006/Jmbi.1993.1532  1
1993 Sontag E, Fedorov S, Kamibayashi C, Robbins D, Cobb M, Mumby M. The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation. Cell. 75: 887-97. PMID 8252625 DOI: 10.1016/0092-8674(93)90533-V  0.32
1992 Robbins DJ, Cobb MH. Extracellular signal-regulated kinases 2 autophosphorylates on a subset of peptides phosphorylated in intact cells in response to insulin and nerve growth factor: analysis by peptide mapping. Molecular Biology of the Cell. 3: 299-308. PMID 1627831  1
1992 Robbins DJ, Cheng M, Zhen E, Vanderbilt CA, Feig LA, Cobb MH. Evidence for a Ras-dependent extracellular signal-regulated protein kinase (ERK) cascade. Proceedings of the National Academy of Sciences of the United States of America. 89: 6924-8. PMID 1495981 DOI: 10.1073/Pnas.89.15.6924  1
1992 Ahn NG, Robbins DJ, Haycock JW, Seger R, Cobb MH, Krebs EG. Identification of an activator of the microtubule-associated protein 2 kinases ERK1 and ERK2 in PC12 cells stimulated with nerve growth factor or bradykinin. Journal of Neurochemistry. 59: 147-56. PMID 1319464 DOI: 10.1111/J.1471-4159.1992.Tb08885.X  1
1991 Cobb MH, Boulton TG, Robbins DJ. Extracellular signal-regulated kinases: ERKs in progress. Cell Regulation. 2: 965-78. PMID 1801927  1
1991 Cobb MH, Robbins DJ, Boulton TG. ERKs, extracellular signal-regulated MAP-2 kinases. Current Opinion in Cell Biology. 3: 1025-32. PMID 1667578 DOI: 10.1016/0955-0674(91)90124-H  1
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