Nicholas H. Brown - Publications

University of Cambridge, Cambridge, England, United Kingdom 

84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Goult BT, Brown NH, Schwartz MA. Talin in mechanotransduction and mechanomemory at a glance. Journal of Cell Science. 134. PMID 34708856 DOI: 10.1242/jcs.258749  0.306
2020 Parra-Acero H, Harcet M, Sánchez-Pons N, Casacuberta E, Brown NH, Dudin O, Ruiz-Trillo I. Integrin-Mediated Adhesion in the Unicellular Holozoan Capsaspora owczarzaki. Current Biology : Cb. PMID 32857975 DOI: 10.1016/J.Cub.2020.08.015  0.492
2019 Green HJ, Brown NH. Integrin intracellular machinery in action. Experimental Cell Research. PMID 30853446 DOI: 10.1016/j.yexcr.2019.03.011  0.425
2018 Richier B, Inoue Y, Dobramysl U, Friedlander J, Brown NH, Gallop JL. Integrin signaling downregulates filopodia in muscle-tendon attachment. Journal of Cell Science. PMID 30054384 DOI: 10.1242/Jcs.217133  0.799
2018 Green HJ, Griffiths AGM, Ylänne J, Brown NH. Novel functions for integrin-associated proteins revealed by analysis of myofibril attachment in . Elife. 7. PMID 30028294 DOI: 10.7554/eLife.35783  0.43
2018 Brown T, Brown N, Stollar EJ. Most yeast SH3 domains bind peptide targets with high intrinsic specificity. Plos One. 13: e0193128. PMID 29470497 DOI: 10.1371/journal.pone.0193128  0.319
2018 Green HJ, Griffiths AG, Ylänne J, Brown NH. Author response: Novel functions for integrin-associated proteins revealed by analysis of myofibril attachment in Drosophila Elife. DOI: 10.22025/Camstag2.55988  0.329
2017 Klapholz B, Brown NH. Talin - the master of integrin adhesions. Journal of Cell Science. PMID 28701514 DOI: 10.1242/jcs.190991  0.472
2017 Bulgakova NA, Wellmann J, Brown NH. Diverse integrin adhesion stoichiometries caused by varied actomyosin activity. Open Biology. 7. PMID 28446705 DOI: 10.1098/rsob.160250  0.43
2016 Gomez JM, Chumakova L, Bulgakova NA, Brown NH. Microtubule organization is determined by the shape of epithelial cells. Nature Communications. 7: 13172. PMID 27779189 DOI: 10.1038/ncomms13172  0.414
2016 Maartens AP, Wellmann J, Wictome E, Klapholz B, Green H, Brown NH. Drosophila vinculin is more harmful when hyperactive than absent, and can circumvent integrin to form adhesion complexes. Journal of Cell Science. PMID 27737911 DOI: 10.1242/jcs.189878  0.46
2016 Huelsmann S, Rintanen N, Sethi R, Brown NH, Ylänne J. Evidence for the mechanosensor function of filamin in tissue development. Scientific Reports. 6: 32798. PMID 27597179 DOI: 10.1038/srep32798  0.423
2015 Bulgakova NA, Brown NH. Drosophila p120catenin is critical for endocytosis of the dynamic E-cadherin-Bazooka complex. Journal of Cell Science. PMID 26698216 DOI: 10.1242/jcs.177527  0.364
2015 Klapholz B, Herbert SL, Wellmann J, Johnson R, Parsons M, Brown NH. Alternative mechanisms for talin to mediate integrin function. Current Biology : Cb. 25: 847-57. PMID 25754646 DOI: 10.1016/j.cub.2015.01.043  0.486
2015 Maartens AP, Brown NH. Anchors and signals: the diverse roles of integrins in development. Current Topics in Developmental Biology. 112: 233-72. PMID 25733142 DOI: 10.1016/bs.ctdb.2014.11.020  0.496
2015 Maartens AP, Brown NH. The many faces of cell adhesion during Drosophila muscle development. Developmental Biology. 401: 62-74. PMID 25596335 DOI: 10.1016/j.ydbio.2014.12.038  0.416
2014 Huelsmann S, Brown NH. Nuclear positioning by actin cables and perinuclear actin: Special and general? Nucleus (Austin, Tex.). 5: 219-23. PMID 24905988 DOI: 10.4161/nucl.29405  0.367
2014 Shulman JM, Imboywa S, Giagtzoglou N, Powers MP, Hu Y, Devenport D, Chipendo P, Chibnik LB, Diamond A, Perrimon N, Brown NH, De Jager PL, Feany MB. Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms. Human Molecular Genetics. 23: 870-7. PMID 24067533 DOI: 10.1093/Hmg/Ddt478  0.696
2013 Osumi-Sutherland D, Marygold SJ, Millburn GH, McQuilton PA, Ponting L, Stefancsik R, Falls K, Brown NH, Gkoutos GV. The Drosophila phenotype ontology. Journal of Biomedical Semantics. 4: 30. PMID 24138933 DOI: 10.1186/2041-1480-4-30  0.736
2013 Huelsmann S, Ylänne J, Brown NH. Filopodia-like actin cables position nuclei in association with perinuclear actin in Drosophila nurse cells. Developmental Cell. 26: 604-15. PMID 24091012 DOI: 10.1016/j.devcel.2013.08.014  0.334
2013 Bulgakova NA, Grigoriev I, Yap AS, Akhmanova A, Brown NH. Dynamic microtubules produce an asymmetric E-cadherin-Bazooka complex to maintain segment boundaries. The Journal of Cell Biology. 201: 887-901. PMID 23751496 DOI: 10.1083/jcb.201211159  0.365
2012 Bulgakova NA, Klapholz B, Brown NH. Cell adhesion in Drosophila: versatility of cadherin and integrin complexes during development. Current Opinion in Cell Biology. 24: 702-12. PMID 22938782 DOI: 10.1016/  0.477
2012 Ratheesh A, Gomez GA, Priya R, Verma S, Kovacs EM, Jiang K, Brown NH, Akhmanova A, Stehbens SJ, Yap AS. Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens. Nature Cell Biology. 14: 818-28. PMID 22750944 DOI: 10.1038/ncb2532  0.395
2012 McQuilton P, St Pierre SE, Thurmond J, Gelbart W, Brown N, Kaufman T, Matthews K, Werner-Washburne M, Cripps R, Crosby L, Dirkmaat A, Emmert D, Gramates LS, Falls K, Matthews B, et al. FlyBase 101 - The basics of navigating FlyBase Nucleic Acids Research. 40: D706-D714. PMID 22127867 DOI: 10.1093/nar/gkr1030  0.699
2011 Brown NH. Extracellular matrix in development: insights from mechanisms conserved between invertebrates and vertebrates. Cold Spring Harbor Perspectives in Biology. 3. PMID 21917993 DOI: 10.1101/cshperspect.a005082  0.417
2011 Zervas CG, Psarra E, Williams V, Solomon E, Vakaloglou KM, Brown NH. A central multifunctional role of integrin-linked kinase at muscle attachment sites. Journal of Cell Science. 124: 1316-27. PMID 21444757 DOI: 10.1242/jcs.081422  0.742
2011 Sabino D, Brown NH, Basto R. Drosophila Ajuba is not an Aurora-A activator but is required to maintain Aurora-A at the centrosome. Journal of Cell Science. 124: 1156-66. PMID 21402878 DOI: 10.1242/jcs.076711  0.466
2010 Bataillé L, Delon I, Da Ponte JP, Brown NH, Jagla K. Downstream of identity genes: muscle-type-specific regulation of the fusion process. Developmental Cell. 19: 317-28. PMID 20708593 DOI: 10.1016/j.devcel.2010.07.008  0.789
2009 Urbano JM, Torgler CN, Molnar C, Tepass U, López-Varea A, Brown NH, de Celis JF, Martín-Bermudo MD. Drosophila laminins act as key regulators of basement membrane assembly and morphogenesis. Development (Cambridge, England). 136: 4165-76. PMID 19906841 DOI: 10.1242/dev.044263  0.781
2009 Delon I, Brown NH. The integrin adhesion complex changes its composition and function during morphogenesis of an epithelium. Journal of Cell Science. 122: 4363-74. PMID 19903692 DOI: 10.1242/jcs.055996  0.81
2008 Brown NH. Spectraplakins: the cytoskeleton's Swiss army knife. Cell. 135: 16-8. PMID 18854149 DOI: 10.1016/j.cell.2008.09.023  0.376
2008 Delon I, Brown N. Cell-Matrix Adhesion: The Wech Connection Current Biology. 18: R389-R391. PMID 18460322 DOI: 10.1016/j.cub.2008.03.047  0.806
2008 Narasimha M, Uv A, Krejci A, Brown NH, Bray SJ. Grainy head promotes expression of septate junction proteins and influences epithelial morphogenesis. Journal of Cell Science. 121: 747-52. PMID 18303052 DOI: 10.1242/jcs.019422  0.68
2007 Tanentzapf G, Devenport D, Godt D, Brown NH. Integrin-dependent anchoring of a stem-cell niche. Nature Cell Biology. 9: 1413-8. PMID 17982446 DOI: 10.1038/ncb1660  0.783
2007 Devenport D, Bunch TA, Bloor JW, Brower DL, Brown NH. Mutations in the Drosophila alphaPS2 integrin subunit uncover new features of adhesion site assembly. Developmental Biology. 308: 294-308. PMID 17618618 DOI: 10.1016/J.Ydbio.2007.02.046  0.799
2007 Estrada B, Maeland AD, Gisselbrecht SS, Bloor JW, Brown NH, Michelson AM. The MARVEL domain protein, Singles Bar, is required for progression past the pre-fusion complex stage of myoblast fusion. Developmental Biology. 307: 328-39. PMID 17537424 DOI: 10.1016/j.ydbio.2007.04.045  0.782
2007 Domínguez-Giménez P, Brown NH, Martín-Bermudo MD. Integrin-ECM interactions regulate the changes in cell shape driving the morphogenesis of the Drosophila wing epithelium. Journal of Cell Science. 120: 1061-71. PMID 17327274 DOI: 10.1242/jcs.03404  0.749
2007 Delon I, Brown NH. Integrins and the actin cytoskeleton. Current Opinion in Cell Biology. 19: 43-50. PMID 17184985 DOI: 10.1016/  0.806
2006 Polesello C, Huelsmann S, Brown NH, Tapon N. The Drosophila RASSF homolog antagonizes the hippo pathway. Current Biology : Cb. 16: 2459-65. PMID 17174922 DOI: 10.1016/J.Cub.2006.10.060  0.393
2006 Tanentzapf G, Brown NH. An interaction between integrin and the talin FERM domain mediates integrin activation but not linkage to the cytoskeleton. Nature Cell Biology. 8: 601-6. PMID 16648844 DOI: 10.1038/ncb1411  0.764
2006 Tanentzapf G, Martin-Bermudo MD, Hicks MS, Brown NH. Multiple factors contribute to integrin-talin interactions in vivo. Journal of Cell Science. 119: 1632-44. PMID 16569666 DOI: 10.1242/jcs.02859  0.803
2006 Narasimha M, Brown NH. Confocal Microscopy of Drosophilia Embryos Cell Biology, Four-Volume Set. 3: 77-86. DOI: 10.1016/B978-012164730-8/50136-2  0.557
2005 Röper K, Mao Y, Brown NH. Contribution of sequence variation in Drosophila actins to their incorporation into actin-based structures in vivo. Journal of Cell Science. 118: 3937-48. PMID 16105877 DOI: 10.1242/jcs.02517  0.416
2005 Bécam IE, Tanentzapf G, Lepesant JA, Brown NH, Huynh JR. Integrin-independent repression of cadherin transcription by talin during axis formation in Drosophila. Nature Cell Biology. 7: 510-6. PMID 15852002 DOI: 10.1038/ncb1253  0.757
2005 Bökel C, Prokop A, Brown NH. Papillote and Piopio: Drosophila ZP-domain proteins required for cell adhesion to the apical extracellular matrix and microtubule organization. Journal of Cell Science. 118: 633-42. PMID 15657084 DOI: 10.1242/Jcs.01619  0.499
2004 Grabbe C, Zervas CG, Hunter T, Brown NH, Palmer RH. Focal adhesion kinase is not required for integrin function or viability in Drosophila. Development (Cambridge, England). 131: 5795-805. PMID 15525665 DOI: 10.1242/Dev.01462  0.742
2004 Devenport D, Brown NH. Morphogenesis in the absence of integrins: mutation of both Drosophila beta subunits prevents midgut migration. Development (Cambridge, England). 131: 5405-15. PMID 15469969 DOI: 10.1242/dev.01427  0.768
2004 Torgler CN, Narasimha M, Knox AL, Zervas CG, Vernon MC, Brown NH. Tensin stabilizes integrin adhesive contacts in Drosophila. Developmental Cell. 6: 357-69. PMID 15030759 DOI: 10.1016/S1534-5807(04)00055-3  0.784
2004 Narasimha M, Brown NH. Novel functions for integrins in epithelial morphogenesis. Current Biology : Cb. 14: 381-5. PMID 15028212 DOI: 10.1016/j.cub.2004.02.033  0.713
2004 Röper K, Brown NH. A spectraplakin is enriched on the fusome and organizes microtubules during oocyte specification in Drosophila. Current Biology : Cb. 14: 99-110. PMID 14738730 DOI: 10.1016/j.cub.2003.12.056  0.389
2003 Torgler CN, Brown NH. Reducing integrins improves the quality of fly life. Science of Aging Knowledge Environment : Sage Ke. 2003: PE28. PMID 14534327 DOI: 10.1126/sageke.2003.40.pe28  0.778
2003 Röper K, Brown NH. Maintaining epithelial integrity: a function for gigantic spectraplakin isoforms in adherens junctions. The Journal of Cell Biology. 162: 1305-15. PMID 14517208 DOI: 10.1083/jcb.200307089  0.481
2002 Brown NH, Gregory SL, Rickoll WL, Fessler LI, Prout M, White RA, Fristrom JW. Talin is essential for integrin function in Drosophila. Developmental Cell. 3: 569-79. PMID 12408808 DOI: 10.1016/S1534-5807(02)00290-3  0.641
2002 Röper K, Gregory SL, Brown NH. The 'spectraplakins': cytoskeletal giants with characteristics of both spectrin and plakin families. Journal of Cell Science. 115: 4215-25. PMID 12376554 DOI: 10.1242/jcs.00157  0.585
2002 Bökel C, Brown NH. Integrins in development: moving on, responding to, and sticking to the extracellular matrix. Developmental Cell. 3: 311-21. PMID 12361595 DOI: 10.1016/S1534-5807(02)00265-4  0.475
2002 Zervas CG, Brown NH. Integrin adhesion: when is a kinase a kinase? Current Biology : Cb. 12: R350-1. PMID 12015134 DOI: 10.1016/S0960-9822(02)00856-4  0.685
2002 Knox AL, Brown NH. Rap1 GTPase regulation of adherens junction positioning and cell adhesion. Science (New York, N.Y.). 295: 1285-8. PMID 11847339 DOI: 10.1126/science.1067549  0.421
2001 Boube M, Martin-Bermudo MD, Brown NH, Casanova J. Specific tracheal migration is mediated by complementary expression of cell surface proteins. Genes & Development. 15: 1554-62. PMID 11410535 DOI: 10.1101/gad.195501  0.747
2001 Zervas CG, Gregory SL, Brown NH. Drosophila integrin-linked kinase is required at sites of integrin adhesion to link the cytoskeleton to the plasma membrane. The Journal of Cell Biology. 152: 1007-18. PMID 11238456 DOI: 10.1083/jcb.152.5.1007  0.792
2000 Martin-Bermudo MD, Brown NH. The localized assembly of extracellular matrix integrin ligands requires cell-cell contact. Journal of Cell Science. 113: 3715-23. PMID 11034900 DOI: 10.13039/501100000288  0.751
2000 Brown NH. An integrin chicken and egg problem: which comes first, the extracellular matrix or the cytoskeleton? Current Opinion in Cell Biology. 12: 629-33. PMID 10978900 DOI: 10.1016/S0955-0674(00)00142-3  0.436
2000 Brown NH. Cell-cell adhesion via the ECM: integrin genetics in fly and worm. Matrix Biology : Journal of the International Society For Matrix Biology. 19: 191-201. PMID 10936444 DOI: 10.1016/S0945-053X(00)00064-0  0.495
2000 Brown NH, Gregory SL, Martin-Bermudo MD. Integrins as mediators of morphogenesis in Drosophila. Developmental Biology. 223: 1-16. PMID 10864456 DOI: 10.1006/dbio.2000.9711  0.778
2000 Kaltschmidt JA, Davidson CM, Brown NH, Brand AH. Rotation and asymmetry of the mitotic spindle direct asymmetric cell division in the developing central nervous system. Nature Cell Biology. 2: 7-12. PMID 10620800 DOI: 10.1038/71323  0.395
1999 Martin-Bermudo MD, Alvarez-Garcia I, Brown NH. Migration of the Drosophila primordial midgut cells requires coordination of diverse PS integrin functions. Development (Cambridge, England). 126: 5161-9. PMID 10529432 DOI: 10.13039/100004440  0.806
1999 Martin-Bermudo MD, Brown NH. Uncoupling integrin adhesion and signaling: the betaPS cytoplasmic domain is sufficient to regulate gene expression in the Drosophila embryo. Genes & Development. 13: 729-39. PMID 10090729 DOI: 10.1101/Gad.13.6.729  0.753
1998 Gregory SL, Brown NH. kakapo, a gene required for adhesion between and within cell layers in Drosophila, encodes a large cytoskeletal linker protein related to plectin and dystrophin. The Journal of Cell Biology. 143: 1271-82. PMID 9832555 DOI: 10.1083/jcb.143.5.1271  0.656
1998 Martin-Bermudo MD, Dunin-Borkowski OM, Brown NH. Modulation of integrin activity is vital for morphogenesis. The Journal of Cell Biology. 141: 1073-81. PMID 9585424 DOI: 10.1083/jcb.141.4.1073  0.751
1998 Bloor JW, Brown NH. Genetic analysis of the Drosophila alphaPS2 integrin subunit reveals discrete adhesive, morphogenetic and sarcomeric functions. Genetics. 148: 1127-42. PMID 9539430  0.809
1998 Prokop A, Martín-Bermudo MD, Bate M, Brown NH. Absence of PS integrins or laminin A affects extracellular adhesion, but not intracellular assembly, of hemiadherens and neuromuscular junctions in Drosophila embryos. Developmental Biology. 196: 58-76. PMID 9527881 DOI: 10.1006/Dbio.1997.8830  0.47
1997 Martin-Bermudo MD, Dunin-Borkowski OM, Brown NH. Specificity of PS integrin function during embryogenesis resides in the alpha subunit extracellular domain. The Embo Journal. 16: 4184-93. PMID 9250662 DOI: 10.1093/emboj/16.14.4184  0.714
1996 Martin-Bermudo MD, Brown NH. Intracellular signals direct integrin localization to sites of function in embryonic muscles. The Journal of Cell Biology. 134: 217-26. PMID 8698816 DOI: 10.1083/jcb.134.1.217  0.728
1995 Dunin-Borkowski OM, Brown NH. Mammalian CD2 is an effective heterologous marker of the cell surface in Drosophila. Developmental Biology. 168: 689-93. PMID 7729601 DOI: 10.1006/dbio.1995.1115  0.313
1993 Brown NH, Bloor JW, Dunin-Borkowski O, Martín-Bermudo MD. lntegrins and morphogenesis. Development (Cambridge, England). 119: 177-83. PMID 27002043  0.802
1993 Brown NH. Integrins hold Drosophila together. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 15: 383-90. PMID 8357340 DOI: 10.1002/bies.950150604  0.483
1993 Brown NH, Bloor JW, Dunin-Borkowski O, Martín-Bermudo MD. Integrins and morphogenesis. Development (Cambridge, England). Supplement. 177-83. PMID 8049471  0.817
1992 St Johnston D, Brown NH, Gall JG, Jantsch M. A conserved double-stranded RNA-binding domain. Proceedings of the National Academy of Sciences of the United States of America. 89: 10979-83. PMID 1438302 DOI: 10.1073/Pnas.89.22.10979  0.318
1990 Jones G, Brown N, Manczak M, Hiremath S, Kafatos FC. Molecular cloning, regulation, and complete sequence of a hemocyanin-related, juvenile hormone-suppressible protein from insect hemolymph Journal of Biological Chemistry. 265: 8596-8602. PMID 2341396  0.485
1989 Bray SJ, Burke B, Brown NH, Hirsh J. Embryonic expression pattern of a family of Drosophila proteins that interact with a central nervous system regulatory element. Genes & Development. 3: 1130-45. PMID 2792757 DOI: 10.1101/Gad.3.8.1130  0.351
1989 Grinblat Y, Brown NH, Kafatos FC. Isolation and characterization of the Drosophila translational elongation factor 2 gene. Nucleic Acids Research. 17: 7303-14. PMID 2508059 DOI: 10.1093/Nar/17.18.7303  0.565
1989 Brown NH, King DL, Wilcox M, Kafatos FC. Developmentally regulated alternative splicing of Drosophila integrin PS2 alpha transcripts. Cell. 59: 185-95. PMID 2507168 DOI: 10.1016/0092-8674(89)90880-5  0.681
1988 Brown NH, Kafatos FC. Functional cDNA libraries from Drosophila embryos. Journal of Molecular Biology. 203: 425-37. PMID 3199441 DOI: 10.1016/0022-2836(88)90010-1  0.504
1987 Bogaert T, Brown N, Wilcox M. The Drosophila PS2 antigen is an invertebrate integrin that, like the fibronectin receptor, becomes localized to muscle attachments Cell. 51: 929-940. PMID 2961459 DOI: 10.1016/0092-8674(87)90580-0  0.636
1984 Wilcox M, Brown N, Piovant M, Smith RJ, White RA. The Drosophila position-specific antigens are a family of cell surface glycoprotein complexes Embo Journal. 3: 2307-2313. PMID 6499831 DOI: 10.1002/J.1460-2075.1984.Tb02131.X  0.557
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