Nicholas H. Brown - Publications

Affiliations: 
University of Cambridge, Cambridge, England, United Kingdom 

87 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Bulgakova NA, Brown NH. Drosophila p120catenin is critical for endocytosis of the dynamic E-cadherin-Bazooka complex. Journal of Cell Science. PMID 26698216 DOI: 10.1242/jcs.177527  1
2015 Matthews BB, Dos Santos G, Crosby MA, Emmert DB, St Pierre SE, Gramates LS, Zhou P, Schroeder AJ, Falls K, Russo SM, Gelbart WM. Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data. G3 (Bethesda, Md.). PMID 26109357 DOI: 10.1534/g3.115.018929  1
2015 Crosby MA, Gramates LS, Dos Santos G, Matthews BB, St Pierre SE, Zhou P, Schroeder AJ, Falls K, Emmert DB, Russo SM, Gelbart WM. Gene Model Annotations for Drosophila melanogaster: The Rule-Benders. G3 (Bethesda, Md.). PMID 26109356 DOI: 10.1534/g3.115.018937  1
2015 Klapholz B, Herbert SL, Wellmann J, Johnson R, Parsons M, Brown NH. Alternative mechanisms for talin to mediate integrin function. Current Biology : Cb. 25: 847-57. PMID 25754646 DOI: 10.1016/j.cub.2015.01.043  1
2015 Maartens AP, Brown NH. Anchors and signals: the diverse roles of integrins in development. Current Topics in Developmental Biology. 112: 233-72. PMID 25733142 DOI: 10.1016/bs.ctdb.2014.11.020  1
2015 Maartens AP, Brown NH. The many faces of cell adhesion during Drosophila muscle development. Developmental Biology. 401: 62-74. PMID 25596335 DOI: 10.1016/j.ydbio.2014.12.038  1
2015 dos Santos G, Schroeder AJ, Goodman JL, Strelets VB, Crosby MA, Thurmond J, Emmert DB, Gelbart WM. FlyBase: introduction of the Drosophila melanogaster Release 6 reference genome assembly and large-scale migration of genome annotations. Nucleic Acids Research. 43: D690-7. PMID 25398896 DOI: 10.1093/nar/gku1099  1
2015 Blake JA, Christie KR, Dolan ME, Drabkin HJ, Hill DP, Ni L, Sitnikov D, Burgess S, Buza T, Gresham C, McCarthy F, Pillai L, Wang H, Carbon S, Dietze H, ... ... Brown NH, et al. Gene Ontology Consortium: Going forward Nucleic Acids Research. 43: D1049-D1056. DOI: 10.1093/nar/gku1179  1
2014 Huelsmann S, Brown NH. Spectraplakins. Current Biology : Cb. 24: R307-8. PMID 24735849 DOI: 10.1016/j.cub.2014.02.003  1
2014 Shulman JM, Imboywa S, Giagtzoglou N, Powers MP, Hu Y, Devenport D, Chipendo P, Chibnik LB, Diamond A, Perrimon N, Brown NH, De Jager PL, Feany MB. Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms. Human Molecular Genetics. 23: 870-7. PMID 24067533 DOI: 10.1093/hmg/ddt478  1
2013 Osumi-Sutherland D, Marygold SJ, Millburn GH, McQuilton PA, Ponting L, Stefancsik R, Falls K, Brown NH, Gkoutos GV. The Drosophila phenotype ontology. Journal of Biomedical Semantics. 4: 30. PMID 24138933 DOI: 10.1186/2041-1480-4-30  1
2013 Huelsmann S, Ylänne J, Brown NH. Filopodia-like actin cables position nuclei in association with perinuclear actin in Drosophila nurse cells. Developmental Cell. 26: 604-15. PMID 24091012 DOI: 10.1016/j.devcel.2013.08.014  1
2013 Bulgakova NA, Grigoriev I, Yap AS, Akhmanova A, Brown NH. Dynamic microtubules produce an asymmetric E-cadherin-Bazooka complex to maintain segment boundaries. The Journal of Cell Biology. 201: 887-901. PMID 23751496 DOI: 10.1083/jcb.201211159  1
2013 Blake JA, Dolan M, Drabkin H, Hill DP, Li N, Sitnikov D, Bridges S, Burgess S, Buza T, McCarthy F, Peddinti D, Pillai L, Carbon S, Dietze H, ... ... Brown NH, et al. Gene Ontology annotations and resources. Nucleic Acids Research. 41: D530-5. PMID 23161678 DOI: 10.1093/nar/gks1050  1
2013 Marygold SJ, Leyland PC, Seal RL, Goodman JL, Thurmond J, Strelets VB, Wilson RJ. FlyBase: improvements to the bibliography. Nucleic Acids Research. 41: D751-7. PMID 23125371 DOI: 10.1093/nar/gks1024  1
2012 Bulgakova NA, Klapholz B, Brown NH. Cell adhesion in Drosophila: versatility of cadherin and integrin complexes during development. Current Opinion in Cell Biology. 24: 702-12. PMID 22938782 DOI: 10.1016/j.ceb.2012.07.006  1
2012 Ratheesh A, Gomez GA, Priya R, Verma S, Kovacs EM, Jiang K, Brown NH, Akhmanova A, Stehbens SJ, Yap AS. Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens. Nature Cell Biology. 14: 818-28. PMID 22750944 DOI: 10.1038/ncb2532  1
2012 Bunt SM, Grumbling GB, Field HI, Marygold SJ, Brown NH, Millburn GH. Directly e-mailing authors of newly published papers encourages community curation. Database : the Journal of Biological Databases and Curation. 2012: bas024. PMID 22554788 DOI: 10.1093/database/bas024  1
2012 Fang R, Schindelman G, Van Auken K, Fernandes J, Chen W, Wang X, Davis P, Tuli MA, Marygold SJ, Millburn G, Matthews B, Zhang H, Brown N, Gelbart WM, Sternberg PW. Automatic categorization of diverse experimental information in the bioscience literature. Bmc Bioinformatics. 13: 16. PMID 22280404 DOI: 10.1186/1471-2105-13-16  0.36
2012 McQuilton P, St Pierre SE, Thurmond J, Gelbart W, Brown N, Kaufman T, Matthews K, Werner-Washburne M, Cripps R, Crosby L, Dirkmaat A, Emmert D, Gramates LS, Falls K, Matthews B, et al. FlyBase 101 - The basics of navigating FlyBase Nucleic Acids Research. 40: D706-D714. PMID 22127867 DOI: 10.1093/nar/gkr1030  1
2012 Blake JA, Dolan M, Drabkin H, Hill DP, Ni L, Sitnikov D, Burgess S, Buza T, Gresham C, McCarthy F, Pillai L, Wang H, Carbon S, Lewis SE, Mungall CJ, ... ... Brown NH, et al. The Gene Ontology: Enhancements for 2011 Nucleic Acids Research. 40: D559-D564. PMID 22102568 DOI: 10.1093/nar/gkr1028  1
2011 Brown NH. Extracellular matrix in development: insights from mechanisms conserved between invertebrates and vertebrates. Cold Spring Harbor Perspectives in Biology. 3. PMID 21917993 DOI: 10.1101/cshperspect.a005082  1
2011 Zervas CG, Psarra E, Williams V, Solomon E, Vakaloglou KM, Brown NH. A central multifunctional role of integrin-linked kinase at muscle attachment sites. Journal of Cell Science. 124: 1316-27. PMID 21444757 DOI: 10.1242/jcs.081422  1
2011 Sabino D, Brown NH, Basto R. Drosophila Ajuba is not an Aurora-A activator but is required to maintain Aurora-A at the centrosome. Journal of Cell Science. 124: 1156-66. PMID 21402878 DOI: 10.1242/jcs.076711  1
2010 Bataillé L, Delon I, Da Ponte JP, Brown NH, Jagla K. Downstream of identity genes: muscle-type-specific regulation of the fusion process. Developmental Cell. 19: 317-28. PMID 20708593 DOI: 10.1016/j.devcel.2010.07.008  1
2009 Urbano JM, Torgler CN, Molnar C, Tepass U, López-Varea A, Brown NH, de Celis JF, Martín-Bermudo MD. Drosophila laminins act as key regulators of basement membrane assembly and morphogenesis. Development (Cambridge, England). 136: 4165-76. PMID 19906841 DOI: 10.1242/dev.044263  1
2009 Delon I, Brown NH. The integrin adhesion complex changes its composition and function during morphogenesis of an epithelium. Journal of Cell Science. 122: 4363-74. PMID 19903692 DOI: 10.1242/jcs.055996  1
2009 Loevenich SN, Brunner E, King NL, Deutsch EW, Stein SE, Aebersold R, Hafen E. The Drosophila melanogaster PeptideAtlas facilitates the use of peptide data for improved fly proteomics and genome annotation. Bmc Bioinformatics. 10: 59. PMID 19210778 DOI: 10.1186/1471-2105-10-59  1
2009 Tweedie S, Ashburner M, Falls K, Leyland P, McQuilton P, Marygold S, Millburn G, Osumi-Sutherland D, Schroeder A, Seal R, Zhang H. FlyBase: enhancing Drosophila Gene Ontology annotations. Nucleic Acids Research. 37: D555-9. PMID 18948289 DOI: 10.1093/nar/gkn788  1
2008 Brown NH. Spectraplakins: the cytoskeleton's Swiss army knife. Cell. 135: 16-8. PMID 18854149 DOI: 10.1016/j.cell.2008.09.023  1
2008 Delon I, Brown N. Cell-Matrix Adhesion: The Wech Connection Current Biology. 18: R389-R391. PMID 18460322 DOI: 10.1016/j.cub.2008.03.047  1
2008 Narasimha M, Uv A, Krejci A, Brown NH, Bray SJ. Grainy head promotes expression of septate junction proteins and influences epithelial morphogenesis. Journal of Cell Science. 121: 747-52. PMID 18303052 DOI: 10.1242/jcs.019422  1
2007 Tanentzapf G, Devenport D, Godt D, Brown NH. Integrin-dependent anchoring of a stem-cell niche. Nature Cell Biology. 9: 1413-8. PMID 17982446 DOI: 10.1038/ncb1660  1
2007 Devenport D, Bunch TA, Bloor JW, Brower DL, Brown NH. Mutations in the Drosophila alphaPS2 integrin subunit uncover new features of adhesion site assembly. Developmental Biology. 308: 294-308. PMID 17618618 DOI: 10.1016/j.ydbio.2007.02.046  1
2007 Estrada B, Maeland AD, Gisselbrecht SS, Bloor JW, Brown NH, Michelson AM. The MARVEL domain protein, Singles Bar, is required for progression past the pre-fusion complex stage of myoblast fusion. Developmental Biology. 307: 328-39. PMID 17537424 DOI: 10.1016/j.ydbio.2007.04.045  1
2007 Domínguez-Giménez P, Brown NH, Martín-Bermudo MD. Integrin-ECM interactions regulate the changes in cell shape driving the morphogenesis of the Drosophila wing epithelium. Journal of Cell Science. 120: 1061-71. PMID 17327274 DOI: 10.1242/jcs.03404  1
2007 Delon I, Brown NH. Integrins and the actin cytoskeleton. Current Opinion in Cell Biology. 19: 43-50. PMID 17184985 DOI: 10.1016/j.ceb.2006.12.013  1
2006 Polesello C, Huelsmann S, Brown NH, Tapon N. The Drosophila RASSF homolog antagonizes the hippo pathway. Current Biology : Cb. 16: 2459-65. PMID 17174922 DOI: 10.1016/j.cub.2006.10.060  1
2006 Tanentzapf G, Brown NH. An interaction between integrin and the talin FERM domain mediates integrin activation but not linkage to the cytoskeleton. Nature Cell Biology. 8: 601-6. PMID 16648844 DOI: 10.1038/ncb1411  1
2006 Tanentzapf G, Martin-Bermudo MD, Hicks MS, Brown NH. Multiple factors contribute to integrin-talin interactions in vivo. Journal of Cell Science. 119: 1632-44. PMID 16569666 DOI: 10.1242/jcs.02859  1
2006 Narasimha M, Brown NH. Confocal Microscopy of Drosophilia Embryos Cell Biology, Four-Volume Set. 3: 77-86. DOI: 10.1016/B978-012164730-8/50136-2  1
2005 Röper K, Mao Y, Brown NH. Contribution of sequence variation in Drosophila actins to their incorporation into actin-based structures in vivo. Journal of Cell Science. 118: 3937-48. PMID 16105877 DOI: 10.1242/jcs.02517  1
2005 Bécam IE, Tanentzapf G, Lepesant JA, Brown NH, Huynh JR. Integrin-independent repression of cadherin transcription by talin during axis formation in Drosophila. Nature Cell Biology. 7: 510-6. PMID 15852002 DOI: 10.1038/ncb1253  1
2005 Bökel C, Prokop A, Brown NH. Papillote and Piopio: Drosophila ZP-domain proteins required for cell adhesion to the apical extracellular matrix and microtubule organization. Journal of Cell Science. 118: 633-42. PMID 15657084 DOI: 10.1242/jcs.01619  1
2004 Grabbe C, Zervas CG, Hunter T, Brown NH, Palmer RH. Focal adhesion kinase is not required for integrin function or viability in Drosophila. Development (Cambridge, England). 131: 5795-805. PMID 15525665 DOI: 10.1242/dev.01462  1
2004 Devenport D, Brown NH. Morphogenesis in the absence of integrins: mutation of both Drosophila beta subunits prevents midgut migration. Development (Cambridge, England). 131: 5405-15. PMID 15469969 DOI: 10.1242/dev.01427  1
2004 Torgler CN, Narasimha M, Knox AL, Zervas CG, Vernon MC, Brown NH. Tensin stabilizes integrin adhesive contacts in Drosophila. Developmental Cell. 6: 357-69. PMID 15030759 DOI: 10.1016/S1534-5807(04)00055-3  1
2004 Narasimha M, Brown NH. Novel functions for integrins in epithelial morphogenesis. Current Biology : Cb. 14: 381-5. PMID 15028212 DOI: 10.1016/j.cub.2004.02.033  1
2004 Röper K, Brown NH. A spectraplakin is enriched on the fusome and organizes microtubules during oocyte specification in Drosophila. Current Biology : Cb. 14: 99-110. PMID 14738730 DOI: 10.1016/j.cub.2003.12.056  1
2003 Torgler CN, Brown NH. Reducing integrins improves the quality of fly life. Science of Aging Knowledge Environment : Sage Ke. 2003: PE28. PMID 14534327 DOI: 10.1126/sageke.2003.40.pe28  1
2003 Röper K, Brown NH. Maintaining epithelial integrity: a function for gigantic spectraplakin isoforms in adherens junctions. The Journal of Cell Biology. 162: 1305-15. PMID 14517208 DOI: 10.1083/jcb.200307089  1
2002 Brown NH, Gregory SL, Rickoll WL, Fessler LI, Prout M, White RA, Fristrom JW. Talin is essential for integrin function in Drosophila. Developmental Cell. 3: 569-79. PMID 12408808 DOI: 10.1016/S1534-5807(02)00290-3  1
2002 Röper K, Gregory SL, Brown NH. The 'spectraplakins': cytoskeletal giants with characteristics of both spectrin and plakin families. Journal of Cell Science. 115: 4215-25. PMID 12376554 DOI: 10.1242/jcs.00157  1
2002 Bökel C, Brown NH. Integrins in development: moving on, responding to, and sticking to the extracellular matrix. Developmental Cell. 3: 311-21. PMID 12361595 DOI: 10.1016/S1534-5807(02)00265-4  1
2002 Zervas CG, Brown NH. Integrin adhesion: when is a kinase a kinase? Current Biology : Cb. 12: R350-1. PMID 12015134 DOI: 10.1016/S0960-9822(02)00856-4  1
2002 Knox AL, Brown NH. Rap1 GTPase regulation of adherens junction positioning and cell adhesion. Science (New York, N.Y.). 295: 1285-8. PMID 11847339 DOI: 10.1126/science.1067549  1
2001 Boube M, Martin-Bermudo MD, Brown NH, Casanova J. Specific tracheal migration is mediated by complementary expression of cell surface proteins. Genes & Development. 15: 1554-62. PMID 11410535 DOI: 10.1101/gad.195501  1
2001 Zervas CG, Gregory SL, Brown NH. Drosophila integrin-linked kinase is required at sites of integrin adhesion to link the cytoskeleton to the plasma membrane. The Journal of Cell Biology. 152: 1007-18. PMID 11238456 DOI: 10.1083/jcb.152.5.1007  1
2000 Martin-Bermudo MD, Brown NH. The localized assembly of extracellular matrix integrin ligands requires cell-cell contact. Journal of Cell Science. 113: 3715-23. PMID 11034900  1
2000 Brown NH. An integrin chicken and egg problem: which comes first, the extracellular matrix or the cytoskeleton? Current Opinion in Cell Biology. 12: 629-33. PMID 10978900 DOI: 10.1016/S0955-0674(00)00142-3  1
2000 Brown NH. Cell-cell adhesion via the ECM: integrin genetics in fly and worm. Matrix Biology : Journal of the International Society For Matrix Biology. 19: 191-201. PMID 10936444 DOI: 10.1016/S0945-053X(00)00064-0  1
2000 Brown NH, Gregory SL, Martin-Bermudo MD. Integrins as mediators of morphogenesis in Drosophila. Developmental Biology. 223: 1-16. PMID 10864456 DOI: 10.1006/dbio.2000.9711  1
2000 Kaltschmidt JA, Davidson CM, Brown NH, Brand AH. Rotation and asymmetry of the mitotic spindle direct asymmetric cell division in the developing central nervous system. Nature Cell Biology. 2: 7-12. PMID 10620800 DOI: 10.1038/71323  1
1999 Martin-Bermudo MD, Alvarez-Garcia I, Brown NH. Migration of the Drosophila primordial midgut cells requires coordination of diverse PS integrin functions. Development (Cambridge, England). 126: 5161-9. PMID 10529432  1
1999 Martin-Bermudo MD, Brown NH. Uncoupling integrin adhesion and signaling: the betaPS cytoplasmic domain is sufficient to regulate gene expression in the Drosophila embryo. Genes & Development. 13: 729-39. PMID 10090729  1
1998 Gregory SL, Brown NH. kakapo, a gene required for adhesion between and within cell layers in Drosophila, encodes a large cytoskeletal linker protein related to plectin and dystrophin. The Journal of Cell Biology. 143: 1271-82. PMID 9832555 DOI: 10.1083/jcb.143.5.1271  1
1998 Walsh EP, Brown NH. A screen to identify Drosophila genes required for integrin-mediated adhesion. Genetics. 150: 791-805. PMID 9755209  1
1998 Martin-Bermudo MD, Dunin-Borkowski OM, Brown NH. Modulation of integrin activity is vital for morphogenesis. The Journal of Cell Biology. 141: 1073-81. PMID 9585424 DOI: 10.1083/jcb.141.4.1073  1
1998 Bloor JW, Brown NH. Genetic analysis of the Drosophila alphaPS2 integrin subunit reveals discrete adhesive, morphogenetic and sarcomeric functions. Genetics. 148: 1127-42. PMID 9539430  1
1998 Prokop A, Martín-Bermudo MD, Bate M, Brown NH. Absence of PS integrins or laminin A affects extracellular adhesion, but not intracellular assembly, of hemiadherens and neuromuscular junctions in Drosophila embryos. Developmental Biology. 196: 58-76. PMID 9527881 DOI: 10.1006/dbio.1997.8830  1
1997 Martin-Bermudo MD, Dunin-Borkowski OM, Brown NH. Specificity of PS integrin function during embryogenesis resides in the alpha subunit extracellular domain. The Embo Journal. 16: 4184-93. PMID 9250662 DOI: 10.1093/emboj/16.14.4184  1
1996 Martin-Bermudo MD, Brown NH. Intracellular signals direct integrin localization to sites of function in embryonic muscles. The Journal of Cell Biology. 134: 217-26. PMID 8698816 DOI: 10.1083/jcb.134.1.217  1
1995 Borkowski OM, Brown NH, Bate M. Anterior-posterior subdivision and the diversification of the mesoderm in Drosophila. Development (Cambridge, England). 121: 4183-93. PMID 8575318  1
1995 Dunin-Borkowski OM, Brown NH. Mammalian CD2 is an effective heterologous marker of the cell surface in Drosophila. Developmental Biology. 168: 689-93. PMID 7729601 DOI: 10.1006/dbio.1995.1115  1
1994 Brown NH, Hartley DA. Drosophila development. Exploring signalling pathways. Nature. 370: 414-5. PMID 8047157 DOI: 10.1038/370414a0  1
1994 Brown NH. Null mutations in the alpha PS2 and beta PS integrin subunit genes have distinct phenotypes. Development (Cambridge, England). 120: 1221-31. PMID 8026331  1
1993 Brown NH, Bloor JW, Dunin-Borkowski O, Martín-Bermudo MD. lntegrins and morphogenesis. Development (Cambridge, England). 119: 177-83. PMID 27002043  1
1993 Brown NH. Integrins hold Drosophila together. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 15: 383-90. PMID 8357340 DOI: 10.1002/bies.950150604  1
1993 Brown NH, Bloor JW, Dunin-Borkowski O, Martín-Bermudo MD. Integrins and morphogenesis. Development (Cambridge, England). Supplement. 177-83. PMID 8049471  1
1992 St Johnston D, Brown NH, Gall JG, Jantsch M. A conserved double-stranded RNA-binding domain. Proceedings of the National Academy of Sciences of the United States of America. 89: 10979-83. PMID 1438302  1
1990 Jones G, Brown N, Manczak M, Hiremath S, Kafatos FC. Molecular cloning, regulation, and complete sequence of a hemocyanin-related, juvenile hormone-suppressible protein from insect hemolymph Journal of Biological Chemistry. 265: 8596-8602. PMID 2341396  1
1989 Bray SJ, Burke B, Brown NH, Hirsh J. Embryonic expression pattern of a family of Drosophila proteins that interact with a central nervous system regulatory element. Genes & Development. 3: 1130-45. PMID 2792757  1
1989 Grinblat Y, Brown NH, Kafatos FC. Isolation and characterization of the Drosophila translational elongation factor 2 gene. Nucleic Acids Research. 17: 7303-14. PMID 2508059 DOI: 10.1093/nar/17.18.7303  1
1989 Brown NH, King DL, Wilcox M, Kafatos FC. Developmentally regulated alternative splicing of Drosophila integrin PS2 alpha transcripts. Cell. 59: 185-95. PMID 2507168 DOI: 10.1016/0092-8674(89)90880-5  1
1988 Brown NH, Kafatos FC. Functional cDNA libraries from Drosophila embryos. Journal of Molecular Biology. 203: 425-37. PMID 3199441 DOI: 10.1016/0022-2836(88)90010-1  1
1987 Bogaert T, Brown N, Wilcox M. The Drosophila PS2 antigen is an invertebrate integrin that, like the fibronectin receptor, becomes localized to muscle attachments Cell. 51: 929-940. PMID 2961459 DOI: 10.1016/0092-8674(87)90580-0  1
1984 Wilcox M, Brown N, Piovant M, Smith RJ, White RA. The Drosophila position-specific antigens are a family of cell surface glycoprotein complexes Embo Journal. 3: 2307-2313. PMID 6499831  1
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