Michael Vitek - Publications

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108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Cao F, Jiang Y, Wu Y, Zhong J, Liu J, Qin X, Chen L, Vitek MP, Li F, Xu L, Sun X. Apolipoprotein E-Mimetic COG1410 Reduces Acute Vasogenic Edema following Traumatic Brain Injury. Journal of Neurotrauma. PMID 26192010 DOI: 10.1089/neu.2015.3887  1
2015 Kan MJ, Lee JE, Wilson JG, Everhart AL, Brown CM, Hoofnagle AN, Jansen M, Vitek MP, Gunn MD, Colton CA. Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5969-82. PMID 25878270 DOI: 10.1523/JNEUROSCI.4668-14.2015  1
2015 Trakhtenberg EF, Morkin MI, Patel KH, Fernandez SG, Sang A, Shaw P, Liu X, Wang Y, Mlacker GM, Gao H, Velmeshev D, Dombrowski SM, Vitek MP, Goldberg JL. The N-terminal Set-β Protein Isoform Induces Neuronal Death. The Journal of Biological Chemistry. 290: 13417-26. PMID 25833944 DOI: 10.1074/jbc.M114.633883  1
2014 Hoos MD, Vitek MP, Ridnour LA, Wilson J, Jansen M, Everhart A, Wink DA, Colton CA. The impact of human and mouse differences in NOS2 gene expression on the brain's redox and immune environment. Molecular Neurodegeneration. 9: 50. PMID 25403885 DOI: 10.1186/1750-1326-9-50  1
2014 Latypova EM, Timoshenko SI, Kislik GA, Vitek M, Shvartsman AL, Sarantseva SV. [Investigation of neuroprotective activity of apolipoprotein E peptide mimetic Cog1410 in transgenic lines of Drosophila melanogaster]. Biomedit͡Sinskai͡a Khimii͡A. 60: 515-21. PMID 25249536  1
2014 Colton CA, Wilson JG, Everhart A, Wilcock DM, Puoliväli J, Heikkinen T, Oksman J, Jääskeläinen O, Lehtimäki K, Laitinen T, Vartiainen N, Vitek MP. mNos2 deletion and human NOS2 replacement in Alzheimer disease models. Journal of Neuropathology and Experimental Neurology. 73: 752-69. PMID 25003233 DOI: 10.1097/NEN.0000000000000094  1
2014 Pippa R, Dominguez A, Christensen DJ, Moreno-Miralles I, Blanco-Prieto MJ, Vitek MP, Odero MD. Effect of FTY720 on the SET-PP2A complex in acute myeloid leukemia; SET binding drugs have antagonistic activity. Leukemia. 28: 1915-8. PMID 24781014 DOI: 10.1038/leu.2014.141  1
2014 Farrell AS, Allen-Petersen B, Daniel CJ, Wang X, Wang Z, Rodriguez S, Impey S, Oddo J, Vitek MP, Lopez C, Christensen DJ, Sheppard B, Sears RC. Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer. Molecular Cancer Research : McR. 12: 924-39. PMID 24667985 DOI: 10.1158/1541-7786.MCR-13-0542  1
2014 Wang R, Hong J, Lu M, Neil JE, Vitek MP, Liu X, Warner DS, Li F, Sheng H. ApoE mimetic ameliorates motor deficit and tissue damage in rat spinal cord injury. Journal of Neuroscience Research. 92: 884-92. PMID 24633884 DOI: 10.1002/jnr.23371  1
2014 Azevedo OG, Bolick DT, Roche JK, Pinkerton RF, Lima AA, Vitek MP, Warren CA, Oriá RB, Guerrant RL. Apolipoprotein E plays a key role against cryptosporidial infection in transgenic undernourished mice. Plos One. 9: e89562. PMID 24586873 DOI: 10.1371/journal.pone.0089562  1
2014 Agarwal A, MacKenzie RJ, Pippa R, Eide CA, Oddo J, Tyner JW, Sears R, Vitek MP, Odero MD, Christensen DJ, Druker BJ. Antagonism of SET using OP449 enhances the efficacy of tyrosine kinase inhibitors and overcomes drug resistance in myeloid leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 2092-103. PMID 24436473 DOI: 10.1158/1078-0432.CCR-13-2575  1
2014 Latypova EM, Timoshenko SI, Kislik GA, Vitek MP, Schwarzman AL, Sarantseva SV. The study of the neuroprotective activity of the apolipoprotein e peptide mimetic Cog1410 in transgenic strains of Drosophila melanogaster Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 8: 37-42. DOI: 10.1134/S1990750814010107  1
2013 Wang H, Anderson LG, Lascola CD, James ML, Venkatraman TN, Bennett ER, Acheson SK, Vitek MP, Laskowitz DT. ApolipoproteinE mimetic peptides improve outcome after focal ischemia. Experimental Neurology. 241: 67-74. PMID 23219883 DOI: 10.1016/j.expneurol.2012.11.027  1
2013 Fujiwara N, Kawasaki H, Yabe R, Christensen DJ, Vitek MP, Mizuno T, Sato K, Ohama T. A potential therapeutic application of SET/I2PP2A inhibitor OP449 for canine T-cell lymphoma. The Journal of Veterinary Medical Science / the Japanese Society of Veterinary Science. 75: 349-54. PMID 23131782 DOI: DN/JST.JSTAGE/jvms/12-0366  1
2013 Ghosal K, Stathopoulos A, Thomas D, Phenis D, Vitek MP, Pimplikar SW. The apolipoprotein-E-mimetic COG112 protects amyloid precursor protein intracellular domain-overexpressing animals from Alzheimer's disease-like pathological features. Neuro-Degenerative Diseases. 12: 51-8. PMID 22965147 DOI: 10.1159/000341299  1
2012 Lei B, Mace B, Bellows ST, Sullivan PM, Vitek MP, Laskowitz DT, James ML. Interaction between sex and apolipoprotein e genetic background in a murine model of intracerebral hemorrhage. Translational Stroke Research. 3: 94-101. PMID 23935764 DOI: 10.1007/s12975-012-0176-7  1
2012 Madenspacher JH, Azzam KM, Gong W, Gowdy KM, Vitek MP, Laskowitz DT, Remaley AT, Wang JM, Fessler MB. Apolipoproteins and apolipoprotein mimetic peptides modulate phagocyte trafficking through chemotactic activity. The Journal of Biological Chemistry. 287: 43730-40. PMID 23118226 DOI: 10.1074/jbc.M112.377192  1
2012 Ridnour LA, Dhanapal S, Hoos M, Wilson J, Lee J, Cheng RY, Brueggemann EE, Hines HB, Wilcock DM, Vitek MP, Wink DA, Colton CA. Nitric oxide-mediated regulation of β-amyloid clearance via alterations of MMP-9/TIMP-1. Journal of Neurochemistry. 123: 736-49. PMID 23016931 DOI: 10.1111/jnc.12028  1
2012 Xu F, Vitek MP, Colton CA, Previti ML, Davis J, Van Nostrand WE. Human apolipoprotein E2 promotes parenchymal amyloid deposition and neuronal loss in vasculotropic mutant amyloid-β protein Tg-SwDI mice. Journal of Alzheimer's Disease : Jad. 31: 359-69. PMID 22635103 DOI: 10.3233/JAD-2012-120421  1
2012 Azevedo OG, Oliveira RA, Oliveira BC, Zaja-Milatovic S, Araújo CV, Wong DV, Costa TB, Lucena HB, Lima RC, Ribeiro RA, Warren CA, Lima AÂ, Vitek MP, Guerrant RL, Oriá RB. Apolipoprotein E COG 133 mimetic peptide improves 5-fluorouracil-induced intestinal mucositis. Bmc Gastroenterology. 12: 35. PMID 22524518 DOI: 10.1186/1471-230X-12-35  1
2012 Yao X, Vitek MP, Remaley AT, Levine SJ. Apolipoprotein mimetic peptides: a new approach for the treatment of asthma. Frontiers in Pharmacology. 3: 37. PMID 22408624 DOI: 10.3389/fphar.2012.00037  1
2012 Vitek MP, Christensen DJ, Wilcock D, Davis J, Van Nostrand WE, Li FQ, Colton CA. APOE-mimetic peptides reduce behavioral deficits, plaques and tangles in Alzheimer's disease transgenics. Neuro-Degenerative Diseases. 10: 122-6. PMID 22326991 DOI: 10.1159/000334914  1
2012 Laskowitz DT, Lei B, Dawson HN, Wang H, Bellows ST, Christensen DJ, Vitek MP, James ML. The apoE-mimetic peptide, COG1410, improves functional recovery in a murine model of intracerebral hemorrhage. Neurocritical Care. 16: 316-26. PMID 21989844 DOI: 10.1007/s12028-011-9641-5  1
2012 Schwarzman AL, Sarantseva SV, Vitek MP. The potential role of presenilin 1 in regulation of synaptic function Cell and Tissue Biology. 6: 60-68. DOI: 10.1134/S1990519X12010117  1
2011 Shvartsman AL, Sarantseva SV, Vitek MP. [Potential role of presenilin 1 in regulation of synaptic function]. Tsitologiia. 53: 959-67. PMID 22359955  1
2011 Switzer CH, Glynn SA, Ridnour LA, Cheng RY, Vitek MP, Ambs S, Wink DA. Nitric oxide and protein phosphatase 2A provide novel therapeutic opportunities in ER-negative breast cancer. Trends in Pharmacological Sciences. 32: 644-51. PMID 21893353 DOI: 10.1016/j.tips.2011.07.001  1
2011 Christensen DJ, Chen Y, Oddo J, Matta KM, Neil J, Davis ED, Volkheimer AD, Lanasa MC, Friedman DR, Goodman BK, Gockerman JP, Diehl LF, de Castro CM, Moore JO, Vitek MP, et al. SET oncoprotein overexpression in B-cell chronic lymphocytic leukemia and non-Hodgkin lymphoma: a predictor of aggressive disease and a new treatment target. Blood. 118: 4150-8. PMID 21844565 DOI: 10.1182/blood-2011-04-351072  1
2011 Switzer CH, Cheng RY, Vitek TM, Christensen DJ, Wink DA, Vitek MP. Targeting SET/I(2)PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy. Oncogene. 30: 2504-13. PMID 21297667 DOI: 10.1038/onc.2010.622  1
2011 Christensen DJ, Ohkubo N, Oddo J, Van Kanegan MJ, Neil J, Li F, Colton CA, Vitek MP. Apolipoprotein E and peptide mimetics modulate inflammation by binding the SET protein and activating protein phosphatase 2A. Journal of Immunology (Baltimore, Md. : 1950). 186: 2535-42. PMID 21289314 DOI: 10.4049/jimmunol.1002847  1
2011 Shipton OA, Leitz JR, Dworzak J, Acton CE, Tunbridge EM, Denk F, Dawson HN, Vitek MP, Wade-Martins R, Paulsen O, Vargas-Caballero M. Tau protein is required for amyloid {beta}-induced impairment of hippocampal long-term potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1688-92. PMID 21289177 DOI: 10.1523/JNEUROSCI.2610-10.2011  1
2011 Wink DA, Hines HB, Cheng RY, Switzer CH, Flores-Santana W, Vitek MP, Ridnour LA, Colton CA. Nitric oxide and redox mechanisms in the immune response. Journal of Leukocyte Biology. 89: 873-91. PMID 21233414 DOI: 10.1189/jlb.1010550  1
2011 Singh K, Chaturvedi R, Barry DP, Coburn LA, Asim M, Lewis ND, Piazuelo MB, Washington MK, Vitek MP, Wilson KT. The apolipoprotein E-mimetic peptide COG112 inhibits NF-kappaB signaling, proinflammatory cytokine expression, and disease activity in murine models of colitis. The Journal of Biological Chemistry. 286: 3839-50. PMID 21115487 DOI: 10.1074/jbc.M110.176719  1
2010 Shvartsman AL, Sarantseva SV, Runova OL, Talalaeva EI, Vitek MP. [Familial Alzheimer's disease mutations in the presenilin 1 gene reduce cell-cell adhesion in transfected fibroblasts]. Biofizika. 55: 862-7. PMID 21033353  1
2010 Laskowitz DT, Song P, Wang H, Mace B, Sullivan PM, Vitek MP, Dawson HN. Traumatic brain injury exacerbates neurodegenerative pathology: improvement with an apolipoprotein E-based therapeutic. Journal of Neurotrauma. 27: 1983-95. PMID 20812776 DOI: 10.1089/neu.2010.1396  1
2010 Kaufman NA, Beare JE, Tan AA, Vitek MP, McKenna SE, Hoane MR. COG1410, an apolipoprotein E-based peptide, improves cognitive performance and reduces cortical loss following moderate fluid percussion injury in the rat. Behavioural Brain Research. 214: 395-401. PMID 20600347 DOI: 10.1016/j.bbr.2010.06.017  1
2010 Dawson HN, Cantillana V, Jansen M, Wang H, Vitek MP, Wilcock DM, Lynch JR, Laskowitz DT. Loss of tau elicits axonal degeneration in a mouse model of Alzheimer's disease. Neuroscience. 169: 516-31. PMID 20434528 DOI: 10.1016/j.neuroscience.2010.04.037  1
2010 Li FQ, Fowler KA, Neil JE, Colton CA, Vitek MP. An apolipoprotein E-mimetic stimulates axonal regeneration and remyelination after peripheral nerve injury. The Journal of Pharmacology and Experimental Therapeutics. 334: 106-15. PMID 20406857 DOI: 10.1124/jpet.110.167882  1
2010 de Barreda EG, Dawson HN, Vitek MP, Avila J. Tau deficiency leads to the upregulation of BAF-57, a protein involved in neuron-specific gene repression. Febs Letters. 584: 2265-70. PMID 20338169 DOI: 10.1016/j.febslet.2010.03.032  1
2010 Gómez de Barreda E, Pérez M, Gómez Ramos P, de Cristobal J, Martín-Maestro P, Morán A, Dawson HN, Vitek MP, Lucas JJ, Hernández F, Avila J. Tau-knockout mice show reduced GSK3-induced hippocampal degeneration and learning deficits. Neurobiology of Disease. 37: 622-9. PMID 20004245 DOI: 10.1016/j.nbd.2009.11.017  1
2010 Schwarzman AL, Sarantseva SV, Runova OL, Talalaeva EI, Vitek MP. Familial Alzheimer's disease mutations in the presenilin 1 gene reduce cell-cell adhesion in transfected fibroblasts Biophysics. 55: 760-764. DOI: 10.1134/S0006350910050131  1
2010 Wilcock DM, Gharkholonarehe N, Van Nostrand WE, Davis J, Vitek MP, Colton CA. Amyloid reduction by amyloid-β vaccination also reduces mouse tau pathology and protects from neuron loss in two mouse models of Alzheimer's disease (The Journal of Neuroscience (2009) (7957-7965)) Journal of Neuroscience. 30: 1197-1198.  1
2009 Sarantseva S, Timoshenko S, Bolshakova O, Karaseva E, Rodin D, Schwarzman AL, Vitek MP. Apolipoprotein E-mimetics inhibit neurodegeneration and restore cognitive functions in a transgenic Drosophila model of Alzheimer's disease. Plos One. 4: e8191. PMID 19997607 DOI: 10.1371/journal.pone.0008191  1
2009 Dunys J, Sevalle J, Giaime E, Pardossi-Piquard R, Vitek MP, Renbaum P, Levy-Lahad E, Zhang YW, Xu H, Checler F, da Costa CA. p53-dependent control of transactivation of the Pen2 promoter by presenilins. Journal of Cell Science. 122: 4003-8. PMID 19889971 DOI: 10.1242/jcs.051169  1
2009 Switzer CH, Ridnour LA, Cheng RY, Sparatore A, Del Soldato P, Moody TW, Vitek MP, Roberts DD, Wink DA. Dithiolethione compounds inhibit Akt signaling in human breast and lung cancer cells by increasing PP2A activity. Oncogene. 28: 3837-46. PMID 19701246 DOI: 10.1038/onc.2009.244  1
2009 Fuster-Matanzo A, de Barreda EG, Dawson HN, Vitek MP, Avila J, Hernández F. Function of tau protein in adult newborn neurons. Febs Letters. 583: 3063-8. PMID 19695252 DOI: 10.1016/j.febslet.2009.08.017  1
2009 Wilcock DM, Gharkholonarehe N, Van Nostrand WE, Davis J, Vitek MP, Colton CA. Amyloid reduction by amyloid-beta vaccination also reduces mouse tau pathology and protects from neuron loss in two mouse models of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 7957-65. PMID 19553436 DOI: 10.1523/JNEUROSCI.1339-09.2009  1
2009 Perez M, Santa-Maria I, Gomez de Barreda E, Zhu X, Cuadros R, Cabrero JR, Sanchez-Madrid F, Dawson HN, Vitek MP, Perry G, Smith MA, Avila J. Tau--an inhibitor of deacetylase HDAC6 function. Journal of Neurochemistry. 109: 1756-66. PMID 19457097 DOI: 10.1111/j.1471-4159.2009.06102.x  1
2009 Wilcock DM, Vitek MP, Colton CA. Vascular amyloid alters astrocytic water and potassium channels in mouse models and humans with Alzheimer's disease. Neuroscience. 159: 1055-69. PMID 19356689 DOI: 10.1016/j.neuroscience.2009.01.023  1
2009 Sarantseva SV, Bol'shakova OI, Timoshenko SI, Kolobov AA, Vitek MP, Shvartsman AL. [Protein transduction domain peptide mediates delivery to the brain via the blood-brain barrier in Drosophila]. Biomedit͡Sinskai͡a Khimii͡A. 55: 41-9. PMID 19351032  1
2009 Sarantseva SV, Bol'shakova OI, Timoshenko SI, Rodin DI, Vitek MP, Shvartsman AL. [Studying pathogenesis of Alzheimer's disease in a Drosophila melanogaster model: human APP overexpression in the brain of transgenic flies leads to deficit of the synaptic protein synaptotagmin]. Genetika. 45: 119-26. PMID 19239106  1
2009 Wang H, Christensen DJ, Vitek MP, Sullivan PM, Laskowitz DT. APOE genotype affects outcome in a murine model of sepsis: implications for a new treatment strategy. Anaesthesia and Intensive Care. 37: 38-45. PMID 19157344  1
2009 Hoane MR, Kaufman N, Vitek MP, McKenna SE. COG1410 improves cognitive performance and reduces cortical neuronal loss in the traumatically injured brain. Journal of Neurotrauma. 26: 121-9. PMID 19119914 DOI: 10.1089/neu.2008.0565  1
2009 James ML, Sullivan PM, Lascola CD, Vitek MP, Laskowitz DT. Pharmacogenomic effects of apolipoprotein e on intracerebral hemorrhage. Stroke; a Journal of Cerebral Circulation. 40: 632-9. PMID 19109539 DOI: 10.1161/STROKEAHA.108.530402  1
2009 Tukhovskaya EA, Yukin AY, Khokhlova ON, Murashev AN, Vitek MP. COG1410, a novel apolipoprotein-E mimetic, improves functional and morphological recovery in a rat model of focal brain ischemia. Journal of Neuroscience Research. 87: 677-82. PMID 18803296 DOI: 10.1002/jnr.21874  1
2009 Vitek MP, Brown CM, Colton CA. APOE genotype-specific differences in the innate immune response. Neurobiology of Aging. 30: 1350-60. PMID 18155324 DOI: 10.1016/j.neurobiolaging.2007.11.014  1
2009 Sarantseva SV, Bolshakova OI, Timoshenko SI, Kolobov AA, Vitek MP, Schwarzman AL. Protein transduction domain peptide mediates delivery to the brain via the blood-brain barrier in Drosophila melanogaster Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 3: 149-155. DOI: 10.1134/S199075080902005X  1
2009 Sarantseva SV, Bolshakova OI, Timoshenko SI, Rodin DI, Vitek M, Schwarzman AL. Studying the pathogenesis of Alzheimer's disease in a Drosophila melanogaster model: Human APP overexpression in the brain of transgenic flies leads to deficit of the synaptic protein synaptotagmin Russian Journal of Genetics. 45: 105-112. DOI: 10.1134/S1022795409010153  1
2008 Shvartsman AL, Sarantseva SV, Solov'ev KV, Runova OL, Talalaeva EI, Vitek MP. [Degeneration of growth cones in a culture of embryonic neurons of mouse with presenilin 1 gene knockout]. Biofizika. 53: 1008-13. PMID 19137685  1
2008 Colton CA, Wilcock DM, Wink DA, Davis J, Van Nostrand WE, Vitek MP. The effects of NOS2 gene deletion on mice expressing mutated human AbetaPP. Journal of Alzheimer's Disease : Jad. 15: 571-87. PMID 19096157  1
2008 Xu F, Vitek MP, Colton CA, Previti ML, Gharkholonarehe N, Davis J, Van Nostrand WE. Human apolipoprotein E redistributes fibrillar amyloid deposition in Tg-SwDI mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5312-20. PMID 18480287 DOI: 10.1523/JNEUROSCI.1042-08.2008  1
2008 Singh K, Chaturvedi R, Asim M, Barry DP, Lewis ND, Vitek MP, Wilson KT. The apolipoprotein E-mimetic peptide COG112 inhibits the inflammatory response to Citrobacter rodentium in colonic epithelial cells by preventing NF-kappaB activation. The Journal of Biological Chemistry. 283: 16752-61. PMID 18417477 DOI: 10.1074/jbc.M710530200  1
2008 Wilcock DM, Lewis MR, Van Nostrand WE, Davis J, Previti ML, Gharkholonarehe N, Vitek MP, Colton CA. Progression of amyloid pathology to Alzheimer's disease pathology in an amyloid precursor protein transgenic mouse model by removal of nitric oxide synthase 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1537-45. PMID 18272675 DOI: 10.1523/JNEUROSCI.5066-07.2008  1
2008 Stopa EG, Butala P, Salloway S, Johanson CE, Gonzalez L, Tavares R, Hovanesian V, Hulette CM, Vitek MP, Cohen RA. Cerebral cortical arteriolar angiopathy, vascular beta-amyloid, smooth muscle actin, Braak stage, and APOE genotype. Stroke; a Journal of Cerebral Circulation. 39: 814-21. PMID 18258839 DOI: 10.1161/STROKEAHA.107.493429  1
2008 Brown CM, Choi E, Xu Q, Vitek MP, Colton CA. The APOE4 genotype alters the response of microglia and macrophages to 17beta-estradiol. Neurobiology of Aging. 29: 1783-94. PMID 17553597 DOI: 10.1016/j.neurobiolaging.2007.04.018  1
2008 Shwartsman AL, Sarantseva SV, Solovyov KV, Runova OL, Talalaeva EI, Vitek MP. Degeneration of growth cones in a culture of embryonic neurons of mouse with presenilin 1 knockout Biophysics. 53: 550-554. DOI: 10.1134/S0006350908060158  1
2007 Ridnour LA, Windhausen AN, Isenberg JS, Yeung N, Thomas DD, Vitek MP, Roberts DD, Wink DA. Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways. Proceedings of the National Academy of Sciences of the United States of America. 104: 16898-903. PMID 17942699 DOI: 10.1073/pnas.0702761104  1
2007 Laskowitz DT, Vitek MP. Apolipoprotein E and neurological disease: therapeutic potential and pharmacogenomic interactions. Pharmacogenomics. 8: 959-69. PMID 17716229 DOI: 10.2217/14622416.8.8.959  1
2007 Dawson HN, Cantillana V, Chen L, Vitek MP. The tau N279K exon 10 splicing mutation recapitulates frontotemporal dementia and parkinsonism linked to chromosome 17 tauopathy in a mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9155-68. PMID 17715352 DOI: 10.1523/JNEUROSCI.5492-06.2007  1
2007 Ohkubo N, Vitek MP, Morishima A, Suzuki Y, Miki T, Maeda N, Mitsuda N. Reelin signals survival through Src-family kinases that inactivate BAD activity. Journal of Neurochemistry. 103: 820-30. PMID 17696989 DOI: 10.1111/j.1471-4159.2007.04804.x  1
2007 Hoane MR, Pierce JL, Holland MA, Birky ND, Dang T, Vitek MP, McKenna SE. The novel apolipoprotein E-based peptide COG1410 improves sensorimotor performance and reduces injury magnitude following cortical contusion injury. Journal of Neurotrauma. 24: 1108-18. PMID 17610351 DOI: 10.1089/neu.2006.0254  1
2007 Laskowitz DT, McKenna SE, Song P, Wang H, Durham L, Yeung N, Christensen D, Vitek MP. COG1410, a novel apolipoprotein E-based peptide, improves functional recovery in a murine model of traumatic brain injury. Journal of Neurotrauma. 24: 1093-107. PMID 17610350 DOI: 10.1089/neu.2006.0192  1
2007 Brown CM, Xu Q, Okhubo N, Vitek MP, Colton CA. Androgen-mediated immune function is altered by the apolipoprotein E gene. Endocrinology. 148: 3383-90. PMID 17395708 DOI: 10.1210/en.2006-1200  1
2007 Wang H, Durham L, Dawson H, Song P, Warner DS, Sullivan PM, Vitek MP, Laskowitz DT. An apolipoprotein E-based therapeutic improves outcome and reduces Alzheimer's disease pathology following closed head injury: evidence of pharmacogenomic interaction. Neuroscience. 144: 1324-33. PMID 17187933 DOI: 10.1016/j.neuroscience.2006.11.017  1
2007 Zipser BD, Johanson CE, Gonzalez L, Berzin TM, Tavares R, Hulette CM, Vitek MP, Hovanesian V, Stopa EG. Microvascular injury and blood-brain barrier leakage in Alzheimer's disease. Neurobiology of Aging. 28: 977-86. PMID 16782234 DOI: 10.1016/j.neurobiolaging.2006.05.016  1
2007 Wang H, Durham L, Dawson H, Song P, Warner DS, Sullivan PM, Vitek MP, Laskowitz DT. Corrigendum to "an apolipoprotein e-based therapeutic improves outcome and reduces alzheimer's disease pathology following closed head injury: Evidence of pharmacogenomic interaction". [Neuroscience 144 (2007) 1324-1333]{star, open} (DOI:10.1016/j.neuroscience.2006.11.017) Neuroscience. 146: 874. DOI: 10.1016/j.neuroscience.2007.01.044  1
2006 Shvartsman AL, Sarantseva SV, Tatishcheva IuA, Runova OL, Talalaeva EI, Vitek MP. [Expression of presenilin 1 on the cell surface in motile polarized cells]. Biofizika. 51: 839-43. PMID 17131822  1
2006 Mesis RG, Wang H, Lombard FW, Yates R, Vitek MP, Borel CO, Warner DS, Laskowitz DT. Dissociation between vasospasm and functional improvement in a murine model of subarachnoid hemorrhage. Neurosurgical Focus. 21: E4. PMID 17029343  1
2006 Colton CA, Mott RT, Sharpe H, Xu Q, Van Nostrand WE, Vitek MP. Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD. Journal of Neuroinflammation. 3: 27. PMID 17005052 DOI: 10.1186/1742-2094-3-27  1
2006 Colton CA, Vitek MP, Wink DA, Xu Q, Cantillana V, Previti ML, Van Nostrand WE, Weinberg JB, Weinberg B, Dawson H. NO synthase 2 (NOS2) deletion promotes multiple pathologies in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 12867-72. PMID 16908860 DOI: 10.1073/pnas.0601075103  1
2006 Laskowitz DT, Fillit H, Yeung N, Toku K, Vitek MP. Apolipoprotein E-derived peptides reduce CNS inflammation: implications for therapy of neurological disease. Acta Neurologica Scandinavica. Supplementum. 185: 15-20. PMID 16866906 DOI: 10.1111/j.1600-0404.2006.00680.x  1
2006 Vitek MP, Brown C, Xu Q, Dawson H, Mitsuda N, Colton CA. Characterization of NO and cytokine production in immune-activated microglia and peritoneal macrophages derived from a mouse model expressing the human NOS2 gene on a mouse NOS2 knockout background. Antioxidants & Redox Signaling. 8: 893-901. PMID 16771679 DOI: 10.1089/ars.2006.8.893  1
2006 Li FQ, Sempowski GD, McKenna SE, Laskowitz DT, Colton CA, Vitek MP. Apolipoprotein E-derived peptides ameliorate clinical disability and inflammatory infiltrates into the spinal cord in a murine model of multiple sclerosis. The Journal of Pharmacology and Experimental Therapeutics. 318: 956-65. PMID 16740622 DOI: 10.1124/jpet.106.103671  1
2006 Jiménez-Mateos EM, González-Billault C, Dawson HN, Vitek MP, Avila J. Role of MAP1B in axonal retrograde transport of mitochondria. The Biochemical Journal. 397: 53-9. PMID 16536727 DOI: 10.1042/BJ20060205  1
2006 Gao J, Wang H, Sheng H, Lynch JR, Warner DS, Durham L, Vitek MP, Laskowitz DT. A novel apoE-derived therapeutic reduces vasospasm and improves outcome in a murine model of subarachnoid hemorrhage. Neurocritical Care. 4: 25-31. PMID 16498192 DOI: 10.1385/NCC:4:1:025  1
2006 Colton CA, Vitek MP. NPY and chronic neurodegenerative disease. Exs. 223-44. PMID 16383010  1
2006 Schwartsman AL, Sarantseva SV, Tatishcheva YA, Runova OL, Talalaeva EI, Vitek MP. Presenilin 1 expression on the cell surface in motile polarized cells Biophysics. 51: 740-743. DOI: 10.1134/S0006350906050125  1
2005 Schwarzman AL, Tsiper M, Gregori L, Goldgaber D, Frakowiak J, Mazur-Kolecka B, Taraskina A, Pchelina S, Vitek MP. Selection of peptides binding to the amyloid b-protein reveals potential inhibitors of amyloid formation. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 12: 199-209. PMID 16399644 DOI: 10.1080/13506120500350762  1
2005 Miao J, Vitek MP, Xu F, Previti ML, Davis J, Van Nostrand WE. Reducing cerebral microvascular amyloid-beta protein deposition diminishes regional neuroinflammation in vasculotropic mutant amyloid precursor protein transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6271-7. PMID 16000616 DOI: 10.1523/JNEUROSCI.1306-05.2005  1
2005 McAdoo JD, Warner DS, Goldberg RN, Vitek MP, Pearlstein R, Laskowitz DT. Intrathecal administration of a novel apoE-derived therapeutic peptide improves outcome following perinatal hypoxic-ischemic injury. Neuroscience Letters. 381: 305-8. PMID 15896489 DOI: 10.1016/j.neulet.2005.02.036  1
2005 Lynch JR, Wang H, Mace B, Leinenweber S, Warner DS, Bennett ER, Vitek MP, McKenna S, Laskowitz DT. A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury. Experimental Neurology. 192: 109-16. PMID 15698624 DOI: 10.1016/j.expneurol.2004.11.014  1
2005 Colton CA, Brown CM, Vitek MP. Sex steroids, APOE genotype and the innate immune system. Neurobiology of Aging. 26: 363-72. PMID 15639315 DOI: 10.1016/j.neurobiolaging.2004.08.001  1
2004 Colton CA, Xu Q, Burke JR, Bae SY, Wakefield JK, Nair A, Strittmatter WJ, Vitek MP. Disrupted spermine homeostasis: a novel mechanism in polyglutamine-mediated aggregation and cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7118-27. PMID 15306645 DOI: 10.1523/JNEUROSCI.1233-04.2004  1
2004 Rissman RA, Poon WW, Blurton-Jones M, Oddo S, Torp R, Vitek MP, LaFerla FM, Rohn TT, Cotman CW. Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology. The Journal of Clinical Investigation. 114: 121-30. PMID 15232619 DOI: 10.1172/JCI20640  1
2004 Schwarzman AL, Tsiper M, Wente H, Wang A, Vitek MP, Vasiliev V, Goldgaber D. Amyloidogenic and anti-amyloidogenic properties of recombinant transthyretin variants. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 11: 1-9. PMID 15185492 DOI: 10.1080/13506120410001667458  1
2004 Dikalov SI, Vitek MP, Mason RP. Cupric-amyloid beta peptide complex stimulates oxidation of ascorbate and generation of hydroxyl radical. Free Radical Biology & Medicine. 36: 340-7. PMID 15036353 DOI: 10.1016/j.freeradbiomed.2003.11.004  1
2004 Rasmussen FH, Yeung N, Kiefer L, Murphy G, Lopez-Otin C, Vitek MP, Moss ML. Use of a multiple-enzyme/multiple-reagent assay system to quantify activity levels in samples containing mixtures of matrix metalloproteinases. Biochemistry. 43: 2987-95. PMID 15023050 DOI: 10.1021/bi036063m  1
2004 Hou L, Shao H, Zhang Y, Li H, Menon NK, Neuhaus EB, Brewer JM, Byeon IJ, Ray DG, Vitek MP, Iwashita T, Makula RA, Przybyla AB, Zagorski MG. Solution NMR studies of the A beta(1-40) and A beta(1-42) peptides establish that the Met35 oxidation state affects the mechanism of amyloid formation. Journal of the American Chemical Society. 126: 1992-2005. PMID 14971932 DOI: 10.1021/ja036813f  1
2004 Colton CA, Needham LK, Brown C, Cook D, Rasheed K, Burke JR, Strittmatter WJ, Schmechel DE, Vitek MP. APOE genotype-specific differences in human and mouse macrophage nitric oxide production. Journal of Neuroimmunology. 147: 62-7. PMID 14741429 DOI: 10.1016/j.jneuroim.2003.10.015  1
2003 Lynch JR, Tang W, Wang H, Vitek MP, Bennett ER, Sullivan PM, Warner DS, Laskowitz DT. APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response. The Journal of Biological Chemistry. 278: 48529-33. PMID 14507923 DOI: 10.1074/jbc.M306923200  1
2002 Colton CA, Brown CM, Cook D, Needham LK, Xu Q, Czapiga M, Saunders AM, Schmechel DE, Rasheed K, Vitek MP. APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress. Neurobiology of Aging. 23: 777-85. PMID 12392781 DOI: 10.1016/S0197-4580(02)00016-7  1
2002 Thomas DD, Espey MG, Vitek MP, Miranda KM, Wink DA. Protein nitration is mediated by heme and free metals through Fenton-type chemistry: an alternative to the NO/O2- reaction. Proceedings of the National Academy of Sciences of the United States of America. 99: 12691-6. PMID 12226478 DOI: 10.1073/pnas.202312699  1
2002 Colton CA, Brown CM, Czapiga M, Vitek MP. Apolipoprotein-E allele-specific regulation of nitric oxide production. Annals of the New York Academy of Sciences. 962: 212-25. PMID 12076977  1
2002 Espey MG, Miranda KM, Thomas DD, Xavier S, Citrin D, Vitek MP, Wink DA. A chemical perspective on the interplay between NO, reactive oxygen species, and reactive nitrogen oxide species. Annals of the New York Academy of Sciences. 962: 195-206. PMID 12076975  1
2002 Brown CM, Wright E, Colton CA, Sullivan PM, Laskowitz DT, Vitek MP. Apolipoprotein E isoform mediated regulation of nitric oxide release. Free Radical Biology & Medicine. 32: 1071-5. PMID 12031891 DOI: 10.1016/S0891-5849(02)00803-1  1
2002 Rapoport M, Dawson HN, Binder LI, Vitek MP, Ferreira A. Tau is essential to beta -amyloid-induced neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 99: 6364-9. PMID 11959919 DOI: 10.1073/pnas.092136199  1
1985 Berger EM, Vitek MP, Morganelli CM. Transcript length heterogeneity at the small heat shock protein genes of Drosophila. Journal of Molecular Biology. 186: 137-48. PMID 2416939 DOI: 10.1016/0022-2836(85)90264-5  1
1984 Vitek MP, Morganelli CM, Berger EM. Stimulation of cytoplasmic actin gene transcription and translation in cultured Drosophila cells by ecdysterone. The Journal of Biological Chemistry. 259: 1738-43. PMID 6693434  1
1984 Vitek MP, Berger EM. Steroid and high-temperature induction of the small heat-shock protein genes in Drosophila. Journal of Molecular Biology. 178: 173-89. PMID 6436495 DOI: 10.1016/0022-2836(84)90138-4  1
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