Georg Halder - Publications


78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Verboven E, Moya IM, Sansores-Garcia L, Xie J, Hillen H, Kowalczyk W, Vella G, Verhulst S, Castaldo SA, Algueró-Nadal A, Romanelli L, Mercader-Celma C, Souza NA, Soheily S, van Huffel L, ... ... Halder G, et al. Regeneration Defects in Yap and Taz Mutant Mouse Livers are Caused by Bile Duct Disruption and Cholestasis. Gastroenterology. PMID 33127392 DOI: 10.1053/j.gastro.2020.10.035  0.48
2020 Verboven E, Moya IM, Halder G. Abstract A13: Yap activity in bile ducts, but not in hepatocytes, is required for normal liver regeneration Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Hippo19-A13  0.36
2019 Moya IM, Castaldo SA, Van den Mooter L, Soheily S, Sansores-Garcia L, Jacobs J, Mannaerts I, Xie J, Verboven E, Hillen H, Algueró-Nadal A, Karaman R, Van Haele M, Kowalczyk W, De Waegeneer M, ... ... Halder G, et al. Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice. Science (New York, N.Y.). 366: 1029-1034. PMID 31754005 DOI: 10.1126/Science.Aaw9886  0.48
2019 Lesaffer B, Verboven E, Van Huffel L, Moya IM, van Grunsven LA, Leclercq IA, Lemaigre FP, Halder G. Comparison of the and Drivers in Bile Ducts of Normal and Injured Mouse Livers. Cells. 8. PMID 31027317 DOI: 10.3390/cells8040380  0.36
2019 Van Haele M, Moya IM, Karaman R, Rens G, Snoeck J, Govaere O, Nevens F, Verslype C, Topal B, Monbaliu D, Halder G, Roskams T. YAP and TAZ Heterogeneity in Primary Liver Cancer: An Analysis of Its Prognostic and Diagnostic Role. International Journal of Molecular Sciences. 20. PMID 30717258 DOI: 10.3390/ijms20030638  0.36
2018 Moya IM, Halder G. Hippo-YAP/TAZ signalling in organ regeneration and regenerative medicine. Nature Reviews. Molecular Cell Biology. PMID 30546055 DOI: 10.1038/s41580-018-0086-y  0.36
2018 Mach J, Atkins M, Gajewski KM, Mottier-Pavie V, Sansores-Garcia L, Xie J, Mills RA, Kowalczyk W, Van Huffel L, Mills GB, Halder G. Modulation of the Hippo pathway and organ growth by RNA processing proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 30257938 DOI: 10.1073/Pnas.1807325115  0.48
2017 Pascual J, Jacobs J, Sansores-Garcia L, Natarajan M, Zeitlinger J, Aerts S, Halder G, Hamaratoglu F. Hippo Reprograms the Transcriptional Response to Ras Signaling. Developmental Cell. 42: 667-680.e4. PMID 28950103 DOI: 10.1016/J.Devcel.2017.08.013  0.52
2017 Wang X, Freire Valls A, Schermann G, Shen Y, Moya IM, Castro L, Urban S, Solecki GM, Winkler F, Riedemann L, Jain RK, Mazzone M, Schmidt T, Fischer T, Halder G, et al. YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis. Developmental Cell. PMID 28867486 DOI: 10.1016/J.Devcel.2017.08.002  0.36
2017 Stradiot L, Verhulst S, Roosens T, Øie CI, Moya IM, Halder G, Mannaerts I, Grunsven LAv. Functionality based method for simultaneous isolation of rodent hepatic sinusoidal cells. Biomaterials. 139: 91-101. PMID 28595132 DOI: 10.1016/J.Biomaterials.2017.05.047  0.36
2016 Moya IM, Halder G. The Hippo pathway in cellular reprogramming and regeneration of different organs. Current Opinion in Cell Biology. 43: 62-68. PMID 27592171 DOI: 10.1016/  0.36
2016 Atkins M, Potier D, Romanelli L, Jacobs J, Mach J, Hamaratoglu F, Aerts S, Halder G. An Ectopic Network of Transcription Factors Regulated by Hippo Signaling Drives Growth and Invasion of a Malignant Tumor Model. Current Biology : Cb. PMID 27476594 DOI: 10.1016/J.Cub.2016.06.035  0.52
2015 Meng Z, Moroishi T, Mottier-Pavie V, Plouffe SW, Hansen CG, Hong AW, Park HW, Mo JS, Lu W, Lu S, Flores F, Yu FX, Halder G, Guan KL. MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. Nature Communications. 6: 8357. PMID 26437443 DOI: 10.1038/ncomms9357  1
2015 Mannaerts I, Leite SB, Verhulst S, Claerhout S, Eysackers N, Thoen LF, Hoorens A, Reynaert H, Halder G, van Grunsven LA. The Hippo pathway effector YAP controls mouse hepatic stellate cell activation. Journal of Hepatology. PMID 25908270 DOI: 10.1016/j.jhep.2015.04.011  1
2015 Verfaillie A, Imrichova H, Atak ZK, Dewaele M, Rambow F, Hulselmans G, Christiaens V, Svetlichnyy D, Luciani F, Van den Mooter L, Claerhout S, Fiers M, Journe F, Ghanem GE, Herrmann C, ... Halder G, et al. Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. Nature Communications. 6: 6683. PMID 25865119 DOI: 10.1038/Ncomms7683  1
2015 Davie K, Jacobs J, Atkins M, Potier D, Christiaens V, Halder G, Aerts S. Discovery of transcription factors and regulatory regions driving in vivo tumor development by ATAC-seq and FAIRE-seq open chromatin profiling. Plos Genetics. 11: e1004994. PMID 25679813 DOI: 10.1371/Journal.Pgen.1004994  1
2015 Yang CC, Graves HK, Moya IM, Tao C, Hamaratoglu F, Gladden AB, Halder G. Differential regulation of the Hippo pathway by adherens junctions and apical-basal cell polarity modules. Proceedings of the National Academy of Sciences of the United States of America. 112: 1785-90. PMID 25624491 DOI: 10.1073/Pnas.1420850112  1
2015 Yang CC, Graves HK, Moya IM, Tao C, Hamaratoglu F, Gladden AB, Halder G. Differential regulation of the Hippo pathway by adherens junctions and apical- Basal cell polarity modules Proceedings of the National Academy of Sciences of the United States of America. 112: 1785-1790. DOI: 10.1073/pnas.1420850112/-/DCSupplemental  1
2014 Mlodzik M, Halder G. Walter J. Gehring (1939-2014). Developmental Biology. 395: 1-3. PMID 25419555 DOI: 10.1016/J.Ydbio.2014.09.007  1
2014 Mlodzik M, Halder G. Walter J Gehring (1939-2014). The Embo Journal. 33: 1615-6. PMID 25006173 DOI: 10.15252/embj.201489291  1
2014 Moya IM, Halder G. Discovering the Hippo pathway protein-protein interactome. Cell Research. 24: 137-8. PMID 24418760 DOI: 10.1038/cr.2014.6  1
2014 Johnson R, Halder G. The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment. Nature Reviews. Drug Discovery. 13: 63-79. PMID 24336504 DOI: 10.1038/nrd4161  1
2014 Bossuyt W, Chen CL, Chen Q, Sudol M, McNeill H, Pan D, Kopp A, Halder G. An evolutionary shift in the regulation of the Hippo pathway between mice and flies. Oncogene. 33: 1218-28. PMID 23563179 DOI: 10.1038/Onc.2013.82  1
2013 Halder G, Camargo FD. The hippo tumor suppressor network: from organ size control to stem cells and cancer. Cancer Research. 73: 6389-92. PMID 24022648 DOI: 10.1158/0008-5472.CAN-13-2392  1
2013 Atkins M, Jiang Y, Sansores-Garcia L, Jusiak B, Halder G, Mardon G. Dynamic rewiring of the Drosophila retinal determination network switches its function from selector to differentiation. Plos Genetics. 9: e1003731. PMID 24009524 DOI: 10.1371/Journal.Pgen.1003731  1
2013 Sansores-Garcia L, Atkins M, Moya IM, Shahmoradgoli M, Tao C, Mills GB, Halder G. Mask is required for the activity of the Hippo pathway effector Yki/YAP. Current Biology : Cb. 23: 229-35. PMID 23333314 DOI: 10.1016/J.Cub.2012.12.033  1
2013 Schroeder MC, Chen CL, Gajewski K, Halder G. A non-cell-autonomous tumor suppressor role for Stat in eliminating oncogenic scribble cells. Oncogene. 32: 4471-9. PMID 23108407 DOI: 10.1038/onc.2012.476  1
2013 Chen CL, Halder G. Cell competition and the hippo pathway The Hippo Signaling Pathway and Cancer. 2147483647: 307-325. DOI: 10.1007/978-1-4614-6220-0_16  0.36
2012 Halder G, Dupont S, Piccolo S. Transduction of mechanical and cytoskeletal cues by YAP and TAZ. Nature Reviews. Molecular Cell Biology. 13: 591-600. PMID 22895435 DOI: 10.1038/Nrm3416  1
2012 Martin A, Papa R, Nadeau NJ, Hill RI, Counterman BA, Halder G, Jiggins CD, Kronforst MR, Long AD, McMillan WO, Reed RD. Diversification of complex butterfly wing patterns by repeated regulatory evolution of a Wnt ligand. Proceedings of the National Academy of Sciences of the United States of America. 109: 12632-7. PMID 22802635 DOI: 10.1073/Pnas.1204800109  1
2012 Schroeder MC, Halder G. Regulation of the Hippo pathway by cell architecture and mechanical signals. Seminars in Cell & Developmental Biology. 23: 803-11. PMID 22750148 DOI: 10.1016/j.semcdb.2012.06.001  1
2012 Graves HK, Woodfield SE, Yang CC, Halder G, Bergmann A. Notch signaling activates Yorkie non-cell autonomously in Drosophila. Plos One. 7: e37615. PMID 22679484 DOI: 10.1371/Journal.Pone.0037615  1
2012 Chen CL, Schroeder MC, Kango-Singh M, Tao C, Halder G. Tumor suppression by cell competition through regulation of the Hippo pathway. Proceedings of the National Academy of Sciences of the United States of America. 109: 484-9. PMID 22190496 DOI: 10.1073/Pnas.1113882109  1
2011 Flores ER, Halder G. Stem cell proliferation in the skin: alpha-catenin takes over the hippo pathway. Science Signaling. 4: pe34. PMID 21791701 DOI: 10.1126/scisignal.2002311  1
2011 Reed RD, Papa R, Martin A, Hines HM, Counterman BA, Pardo-Diaz C, Jiggins CD, Chamberlain NL, Kronforst MR, Chen R, Halder G, Nijhout HF, McMillan WO. optix drives the repeated convergent evolution of butterfly wing pattern mimicry. Science (New York, N.Y.). 333: 1137-41. PMID 21778360 DOI: 10.1126/Science.1208227  1
2011 McNeill H, Sudol M, Halder G, Strano S, Blandino G, Shaul Y. The Hippo tumor suppressor pathway: a report on 'the Second Workshop On The Hippo tumor suppressor pathway'. Cell Death and Differentiation. 18: 1388-90. PMID 21566666 DOI: 10.1038/Cdd.2011.61  1
2011 Sansores-Garcia L, Bossuyt W, Wada K, Yonemura S, Tao C, Sasaki H, Halder G. Modulating F-actin organization induces organ growth by affecting the Hippo pathway. The Embo Journal. 30: 2325-35. PMID 21556047 DOI: 10.1038/emboj.2011.157  1
2011 Halder G, Mills GB. Drosophila in cancer research: to boldly go where no one has gone before. Oncogene. 30: 4063-6. PMID 21499298 DOI: 10.1038/onc.2011.128  1
2011 Halder G, Johnson RL. Hippo signaling: growth control and beyond. Development (Cambridge, England). 138: 9-22. PMID 21138973 DOI: 10.1242/dev.045500  1
2010 Chen CL, Gajewski KM, Hamaratoglu F, Bossuyt W, Sansores-Garcia L, Tao C, Halder G. The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 107: 15810-5. PMID 20798049 DOI: 10.1073/Pnas.1004060107  1
2010 Counterman BA, Araujo-Perez F, Hines HM, Baxter SW, Morrison CM, Lindstrom DP, Papa R, Ferguson L, Joron M, Ffrench-Constant RH, Smith CP, Nielsen DM, Chen R, Jiggins CD, Reed RD, ... Halder G, et al. Genomic hotspots for adaptation: the population genetics of Müllerian mimicry in Heliconius erato. Plos Genetics. 6: e1000796. PMID 20140239 DOI: 10.1371/Journal.Pgen.1000796  1
2010 Lu L, Li Y, Kim SM, Bossuyt W, Liu P, Qiu Q, Wang Y, Halder G, Finegold MJ, Lee JS, Johnson RL. Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. Proceedings of the National Academy of Sciences of the United States of America. 107: 1437-42. PMID 20080689 DOI: 10.1073/pnas.0911427107  1
2010 Morrison CM, Halder G. Characterization of a dorsal-eye Gal4 Line in Drosophila. Genesis (New York, N.Y. : 2000). 48: 3-7. PMID 19882738 DOI: 10.1002/dvg.20571  1
2009 Hamaratoglu F, Gajewski K, Sansores-Garcia L, Morrison C, Tao C, Halder G. The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth. Journal of Cell Science. 122: 2351-9. PMID 19531584 DOI: 10.1242/Jcs.046482  1
2008 Willecke M, Hamaratoglu F, Sansores-Garcia L, Tao C, Halder G. Boundaries of Dachsous Cadherin activity modulate the Hippo signaling pathway to induce cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 105: 14897-902. PMID 18809931 DOI: 10.1073/Pnas.0805201105  1
2008 Papa R, Morrison CM, Walters JR, Counterman BA, Chen R, Halder G, Ferguson L, Chamberlain N, Ffrench-Constant R, Kapan DD, Jiggins CD, Reed RD, McMillan WO. Highly conserved gene order and numerous novel repetitive elements in genomic regions linked to wing pattern variation in Heliconius butterflies. Bmc Genomics. 9: 345. PMID 18647405 DOI: 10.1186/1471-2164-9-345  1
2008 Chamilos G, Lewis RE, Hu J, Xiao L, Zal T, Gilliet M, Halder G, Kontoyiannis DP. Drosophila melanogaster as a model host to dissect the immunopathogenesis of zygomycosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 9367-72. PMID 18583479 DOI: 10.1073/pnas.0709578105  1
2007 Zhao B, Wei X, Li W, Udan RS, Yang Q, Kim J, Xie J, Ikenoue T, Yu J, Li L, Zheng P, Ye K, Chinnaiyan A, Halder G, Lai ZC, et al. Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes & Development. 21: 2747-61. PMID 17974916 DOI: 10.1101/Gad.1602907  1
2006 Childress JL, Acar M, Tao C, Halder G. Lethal giant discs, a novel C2-domain protein, restricts notch activation during endocytosis. Current Biology : Cb. 16: 2228-33. PMID 17088062 DOI: 10.1016/J.Cub.2006.09.031  1
2006 Anbanandam A, Albarado DC, Nguyen CT, Halder G, Gao X, Veeraraghavan S. Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain. Proceedings of the National Academy of Sciences of the United States of America. 103: 17225-30. PMID 17085591 DOI: 10.1073/Pnas.0607171103  1
2006 Willecke M, Hamaratoglu F, Kango-Singh M, Udan R, Chen CL, Tao C, Zhang X, Halder G. The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size. Current Biology : Cb. 16: 2090-100. PMID 16996265 DOI: 10.1016/J.Cub.2006.09.005  1
2006 Nolo R, Morrison CM, Tao C, Zhang X, Halder G. The bantam microRNA is a target of the hippo tumor-suppressor pathway. Current Biology : Cb. 16: 1895-904. PMID 16949821 DOI: 10.1016/j.cub.2006.08.057  1
2006 Chamilos G, Lionakis MS, Lewis RE, Lopez-Ribot JL, Saville SP, Albert ND, Halder G, Kontoyiannis DP. Drosophila melanogaster as a facile model for large-scale studies of virulence mechanisms and antifungal drug efficacy in Candida species. The Journal of Infectious Diseases. 193: 1014-22. PMID 16518764 DOI: 10.1086/500950  1
2006 Hamaratoglu F, Willecke M, Kango-Singh M, Nolo R, Hyun E, Tao C, Jafar-Nejad H, Halder G. The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nature Cell Biology. 8: 27-36. PMID 16341207 DOI: 10.1038/Ncb1339  1
2005 Eder AM, Sui X, Rosen DG, Nolden LK, Cheng KW, Lahad JP, Kango-Singh M, Lu KH, Warneke CL, Atkinson EN, Bedrosian I, Keyomarsi K, Kuo WL, Gray JW, Yin JC, ... ... Halder G, et al. Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer. Proceedings of the National Academy of Sciences of the United States of America. 102: 12519-24. PMID 16116079 DOI: 10.1073/Pnas.0505641102  1
2005 Lionakis MS, Lewis RE, May GS, Wiederhold NP, Albert ND, Halder G, Kontoyiannis DP. Toll-deficient Drosophila flies as a fast, high-throughput model for the study of antifungal drug efficacy against invasive aspergillosis and Aspergillus virulence. The Journal of Infectious Diseases. 191: 1188-95. PMID 15747256 DOI: 10.1086/428587  1
2004 Kango-Singh M, Halder G. Drosophila as an emerging model to study metastasis. Genome Biology. 5: 216. PMID 15059249 DOI: 10.1186/Gb-2004-5-4-216  1
2003 Udan RS, Kango-Singh M, Nolo R, Tao C, Halder G. Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway. Nature Cell Biology. 5: 914-20. PMID 14502294 DOI: 10.1038/Ncb1050  1
2002 Kango-Singh M, Nolo R, Tao C, Verstreken P, Hiesinger PR, Bellen HJ, Halder G. Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila. Development (Cambridge, England). 129: 5719-30. PMID 12421711 DOI: 10.1242/Dev.00168  1
2002 Curtiss J, Halder G, Mlodzik M. Selector and signalling molecules cooperate in organ patterning. Nature Cell Biology. 4: E48-51. PMID 11875444 DOI: 10.1038/ncb0302-e48  1
2001 Halder G, Carroll SB. Binding of the Vestigial co-factor switches the DNA-target selectivity of the Scalloped selector protein. Development (Cambridge, England). 128: 3295-305. PMID 11546746  1
2000 Nussbaumer U, Halder G, Groppe J, Affolter M, Montagne J. Expression of the blistered/DSRF gene is controlled by different morphogens during Drosophila trachea and wing development. Mechanisms of Development. 96: 27-36. PMID 10940622 DOI: 10.1016/S0925-4773(00)00373-7  1
1999 Lewis DL, DeCamillis MA, Brunetti CR, Halder G, Kassner VA, Selegue JE, Higgs S, Carroll SB. Ectopic gene expression and homeotic transformations in arthropods using recombinant Sindbis viruses. Current Biology : Cb. 9: 1279-87. PMID 10574759 DOI: 10.1016/S0960-9822(00)80049-4  1
1999 Halder G, Paddock SW. Presentation of confocal images. Methods in Molecular Biology (Clifton, N.J.). 122: 373-84. PMID 10391717  1
1999 Czerny T, Halder G, Kloter U, Souabni A, Gehring WJ, Busslinger M. twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development. Molecular Cell. 3: 297-307. PMID 10198632 DOI: 10.1016/S1097-2765(00)80457-8  1
1999 Weatherbee SD, Nijhout HF, Grunert LW, Halder G, Galant R, Selegue J, Carroll S. Ultrabithorax function in butterfly wings and the evolution of insect wing patterns. Current Biology : Cb. 9: 109-15. PMID 10021383 DOI: 10.1016/S0960-9822(99)80064-5  1
1999 Chen R, Halder G, Zhang Z, Mardon G. Signaling by the TGF-beta homolog decapentaplegic functions reiteratively within the network of genes controlling retinal cell fate determination in Drosophila. Development (Cambridge, England). 126: 935-43. PMID 9927595  1
1998 Halder G, Polaczyk P, Kraus ME, Hudson A, Kim J, Laughon A, Carroll S. The Vestigial and Scalloped proteins act together to directly regulate wing-specific gene expression in Drosophila. Genes & Development. 12: 3900-9. PMID 9869643 DOI: 10.1101/Gad.12.24.3900  1
1998 Weatherbee SD, Halder G, Kim J, Hudson A, Carroll S. Ultrabithorax regulates genes at several levels of the wing-patterning hierarchy to shape the development of the Drosophila haltere. Genes & Development. 12: 1474-82. PMID 9585507 DOI: 10.1101/Gad.12.10.1474  1
1998 Halder G, Callaerts P, Flister S, Walldorf U, Kloter U, Gehring WJ. Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development. Development (Cambridge, England). 125: 2181-91. PMID 9584118  1
1997 Tomarev SI, Callaerts P, Kos L, Zinovieva R, Halder G, Gehring W, Piatigorsky J. Squid Pax-6 and eye development. Proceedings of the National Academy of Sciences of the United States of America. 94: 2421-6. PMID 9122210 DOI: 10.1073/Pnas.94.6.2421  1
1997 Callaerts P, Halder G, Gehring WJ. PAX-6 in development and evolution. Annual Review of Neuroscience. 20: 483-532. PMID 9056723 DOI: 10.1146/annurev.neuro.20.1.483  1
1997 Glardon S, Callaerts P, Halder G, Gehring WJ. Conservation of Pax-6 in a lower chordate, the ascidian Phallusia mammillata. Development (Cambridge, England). 124: 817-25. PMID 9043063  1
1996 Tomarev S, Callaerts P, Kos L, Zinovieva R, Halder G, Gehring W, Piatigorsky J. Pax-6 and eye development in invertebrates Investigative Ophthalmology and Visual Science. 37: S199.  1
1995 Halder G, Callaerts P, Gehring WJ. New perspectives on eye evolution. Current Opinion in Genetics & Development. 5: 602-9. PMID 8664548 DOI: 10.1016/0959-437X(95)80029-8  1
1995 Halder G, Callaerts P, Gehring WJ. Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila. Science (New York, N.Y.). 267: 1788-92. PMID 7892602 DOI: 10.1126/Science.7892602  1
1994 Arber S, Halder G, Caroni P. Muscle LIM protein, a novel essential regulator of myogenesis, promotes myogenic differentiation. Cell. 79: 221-31. PMID 7954791 DOI: 10.1016/0092-8674(94)90192-9  1
1957 PSCHYREMBEL W, HALDER G. [New method for separation of estrogen hormones based on the Kober test]. Hoppe-Seyler's Zeitschrift FüR Physiologische Chemie. 306: 154-64. PMID 13415566 DOI: 10.1515/bchm2.1957.306.1-2.154  0.01
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