Bret D. Wallace, Ph.D. - Publications

Affiliations: 
2012 Chemistry University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Structural Studies of Dynamic Cellular Processes

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Challa AP, Hu X, Zhang YQ, Hymes J, Wallace BD, Karavadhi S, Sun H, Patnaik S, Hall MD, Shen M. Virtual Screening for the Discovery of Microbiome β-Glucuronidase Inhibitors to Alleviate Cancer Drug Toxicity. Journal of Chemical Information and Modeling. 62: 1783-1793. PMID 35357819 DOI: 10.1021/acs.jcim.1c01414  0.427
2020 Bhatt AP, Pellock SJ, Biernat KA, Walton WG, Wallace BD, Creekmore BC, Letertre MM, Swann JR, Wilson ID, Roques JR, Darr DB, Bailey ST, Montgomery SA, Roach JM, Azcarate-Peril MA, et al. Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy. Proceedings of the National Academy of Sciences of the United States of America. PMID 32170007 DOI: 10.1073/Pnas.1918095117  0.649
2016 Appel CD, Feld GK, Wallace BD, Williams RS. Structure of the Sirtuin-linked Macrodomain SAV0325 from Staphylococcus aureus. Protein Science : a Publication of the Protein Society. PMID 27345688 DOI: 10.1002/Pro.2974  0.357
2015 Wallace BD, Roberts AB, Pollet RM, Ingle JD, Biernat KA, Pellock SJ, Venkatesh MK, Guthrie L, O'Neal SK, Robinson SJ, Dollinger M, Figueroa E, McShane SR, Cohen RD, Jin J, et al. Structure and Inhibition of Microbiome β-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity. Chemistry & Biology. 22: 1238-49. PMID 26364932 DOI: 10.1016/J.Chembiol.2015.08.005  0.709
2015 Pollet R, Wallace B, Robers A, Boelsterli U, Mani S, Redinbo M. Pharmaceutical Control of the Microbiome The Faseb Journal. 29. DOI: 10.1096/Fasebj.29.1_Supplement.575.13  0.696
2013 Roberts AB, Wallace BD, Venkatesh MK, Mani S, Redinbo MR. Molecular insights into microbial β-glucuronidase inhibition to abrogate CPT-11 toxicity. Molecular Pharmacology. 84: 208-17. PMID 23690068 DOI: 10.1124/Mol.113.085852  0.684
2013 Wallace BD, Redinbo MR. The human microbiome is a source of therapeutic drug targets. Current Opinion in Chemical Biology. 17: 379-84. PMID 23680493 DOI: 10.1016/J.Cbpa.2013.04.011  0.662
2013 Wallace BD, Betts L, Talmage G, Pollet RM, Holman NS, Redinbo MR. Structural and functional analysis of the human nuclear xenobiotic receptor PXR in complex with RXRα. Journal of Molecular Biology. 425: 2561-77. PMID 23602807 DOI: 10.1016/J.Jmb.2013.04.012  0.689
2013 Wallace BD, Redinbo MR. Xenobiotic-sensing nuclear receptors involved in drug metabolism: a structural perspective. Drug Metabolism Reviews. 45: 79-100. PMID 23210723 DOI: 10.3109/03602532.2012.740049  0.606
2012 Wallace BD, Edwards JS, Wallen JR, Moolman WJ, van der Westhuyzen R, Strauss E, Redinbo MR, Claiborne A. Turnover-dependent covalent inactivation of Staphylococcus aureus coenzyme A-disulfide reductase by coenzyme A-mimetics: mechanistic and structural insights. Biochemistry. 51: 7699-711. PMID 22954034 DOI: 10.1021/Bi301026C  0.685
2012 LoGuidice A, Wallace BD, Bendel L, Redinbo MR, Boelsterli UA. Pharmacologic targeting of bacterial β-glucuronidase alleviates nonsteroidal anti-inflammatory drug-induced enteropathy in mice. The Journal of Pharmacology and Experimental Therapeutics. 341: 447-54. PMID 22328575 DOI: 10.1124/Jpet.111.191122  0.647
2010 Wallace BD, Wang H, Lane KT, Scott JE, Orans J, Koo JS, Venkatesh M, Jobin C, Yeh LA, Mani S, Redinbo MR. Alleviating cancer drug toxicity by inhibiting a bacterial enzyme. Science (New York, N.Y.). 330: 831-5. PMID 21051639 DOI: 10.1126/Science.1191175  0.72
2010 Parsonage D, Newton GL, Holder RC, Wallace BD, Paige C, Hamilton CJ, Dos Santos PC, Redinbo MR, Reid SD, Claiborne A. Characterization of the N-acetyl-α-D-glucosaminyl l-malate synthase and deacetylase functions for bacillithiol biosynthesis in Bacillus anthracis . Biochemistry. 49: 8398-414. PMID 20799687 DOI: 10.1021/Bi100698N  0.583
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