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Megan Mayerle, Ph.D. - Publications

Affiliations: 
2012 Biology Johns Hopkins University, Baltimore, MD 
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13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mayerle M, Yitiz S, Soulette C, Rogel LE, Ramirez A, Ragle JM, Katzman S, Guthrie C, Zahler AM. Prp8 impacts cryptic but not alternative splicing frequency. Proceedings of the National Academy of Sciences of the United States of America. PMID 30674666 DOI: 10.1073/Pnas.1819020116  0.41
2018 MacRae AJ, Mayerle M, Hrabeta-Robinson E, Chalkley RJ, Guthrie C, Burlingame AL, Jurica M. Prp8 positioning of U5 snRNA is linked to 5' splice site recognition. Rna (New York, N.Y.). PMID 29487104 DOI: 10.1261/Rna.065458.117  0.484
2018 MacRae A, Mayerle M, Chalkley R, Jurica M. A Flexible Region of PRP8 Interacts with U5 snRNA Loop I and is Functionally Linked to 5' Splice Site Recognition Biophysical Journal. 114: 253a. DOI: 10.1016/J.Bpj.2017.11.1405  0.393
2017 Mayerle M, Raghavan M, Ledoux S, Price A, Stepankiw N, Hadjivassiliou H, Moehle EA, Mendoza SD, Pleiss JA, Guthrie C, Abelson J. Structural toggle in the RNaseH domain of Prp8 helps balance splicing fidelity and catalytic efficiency. Proceedings of the National Academy of Sciences of the United States of America. PMID 28416677 DOI: 10.1073/Pnas.1701462114  0.403
2017 Mayerle M, Guthrie C. Genetics and Biochemistry Remain Essential in the Structural Era of the Spliceosome. Methods (San Diego, Calif.). PMID 28132896 DOI: 10.1016/J.Ymeth.2017.01.006  0.399
2016 Mayerle M, Guthrie C. Prp8 retinitis pigmentosa mutants cause defects in the transition between the catalytic steps of splicing. Rna (New York, N.Y.). PMID 26968627 DOI: 10.1261/Rna.055459.115  0.372
2016 Mayerle M, Guthrie C. A new communication hub in the RNA world. Nature Structural & Molecular Biology. 23: 189-90. PMID 26931416 DOI: 10.1038/Nsmb.3178  0.523
2014 Kim H, Abeysirigunawarden SC, Chen K, Mayerle M, Ragunathan K, Luthey-Schulten Z, Ha T, Woodson SA. Protein-guided RNA dynamics during early ribosome assembly. Nature. 506: 334-8. PMID 24522531 DOI: 10.1038/Nature13039  0.729
2014 Mayerle M, Abelson J, Guthrie C. Development of an smFRET Assay to Monitor Spliceosome Activation in Budding Yeast Biophysical Journal. 106: 496a. DOI: 10.1016/J.Bpj.2013.11.2774  0.435
2013 Mayerle M, Woodson SA. Specific contacts between protein S4 and ribosomal RNA are required at multiple stages of ribosome assembly. Rna (New York, N.Y.). 19: 574-85. PMID 23431409 DOI: 10.1261/Rna.037028.112  0.741
2012 Chen K, Eargle J, Lai J, Kim H, Abeysirigunawardena S, Mayerle M, Woodson S, Ha T, Luthey-Schulten Z. Assembly of the five-way junction in the ribosomal small subunit using hybrid MD-Gō simulations. The Journal of Physical Chemistry. B. 116: 6819-31. PMID 22458631 DOI: 10.1021/Jp212614B  0.71
2012 Kim H, Abeysirigunawardena S, Mayerle M, Ragunathan K, Chen K, Eargle J, Luthey-Schulten Z, Woodson S, Ha T. Single Molecule Views of the Ribosome Assembly Biophysical Journal. 102: 645a. DOI: 10.1016/J.Bpj.2011.11.3512  0.714
2011 Mayerle M, Bellur DL, Woodson SA. Slow formation of stable complexes during coincubation of minimal rRNA and ribosomal protein S4. Journal of Molecular Biology. 412: 453-65. PMID 21821049 DOI: 10.1016/J.Jmb.2011.07.048  0.6
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