Thomas Vaccari, Ph.D. - Publications

IFOM -FIRC Institute of Molecular Oncology 
signaling, endocytosis, Notch, ESCRT, V-ATPase

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Frappaolo A, Karimpour-Ghahnavieh A, Cesare G, Sechi S, Fraschini R, Vaccari T, Giansanti MG. GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila. Cell Death & Disease. 13: 1003. PMID 36435842 DOI: 10.1038/s41419-022-05438-9  0.422
2022 Smeele PH, Vaccari T. Snapshots from within the cell: Novel trafficking and non trafficking functions of Snap29 during tissue morphogenesis. Seminars in Cell & Developmental Biology. PMID 35256275 DOI: 10.1016/j.semcdb.2022.02.024  0.349
2021 Formica M, Storaci AM, Bertolini I, Carminati F, Knævelsrud H, Vaira V, Vaccari T. V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis. Autophagy. 1-11. PMID 33978540 DOI: 10.1080/15548627.2021.1918915  0.338
2020 Galeone A, Adams JM, Matsuda S, Presa MF, Pandey A, Han SY, Tachida Y, Hirayama H, Vaccari T, Suzuki T, Lutz CM, Affolter M, Zuberi A, Jafar-Nejad H. Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation. Elife. 9. PMID 32720893 DOI: 10.7554/Elife.55596  0.443
2020 Galeone A, Adams JM, Matsuda S, Presa MF, Pandey A, Han SY, Tachida Y, Hirayama H, Vaccari T, Suzuki T, Lutz CM, Affolter M, Zuberi A, Jafar-Nejad H. Author response: Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation Elife. DOI: 10.7554/Elife.55596.Sa2  0.38
2019 Luna-Peláez N, March-Díaz R, Ceballos-Chávez M, Guerrero-Martínez JA, Grazioli P, García-Gutiérrez P, Vaccari T, Massa V, Reyes JC, García-Domínguez M. The Cornelia de Lange Syndrome-associated factor NIPBL interacts with BRD4 ET domain for transcription control of a common set of genes. Cell Death & Disease. 10: 548. PMID 31320616 DOI: 10.1038/s41419-019-1792-x  0.402
2019 Russo A, Gatti G, Alfieri R, Pesce E, Soanes K, Ricciardi S, Mancino M, Cheroni C, Vaccari T, Biffo S, Calamita P. Modulating eIF6 levels unveils the role of translation in ecdysone biosynthesis during Drosophila development. Developmental Biology. PMID 31283922 DOI: 10.1016/j.ydbio.2019.05.013  0.413
2019 Gualtieri M, Vaccari T. Genetic and Cell Biology Methods to Study ESCRTs in Drosophila melanogaster. Methods in Molecular Biology (Clifton, N.J.). 1998: 13-29. PMID 31250291 DOI: 10.1007/978-1-4939-9492-2_2  0.416
2019 Terrasi A, Bertolini I, Martelli C, Gaudioso G, Di Cristofori A, Storaci AM, Formica M, Bosari S, Caroli M, Ottobrini L, Vaccari T, Vaira V. Specific V-ATPase expression sub-classifies IDHwt lower-grade gliomas and impacts glioma growth in vivo. Ebiomedicine. PMID 30737087 DOI: 10.1016/j.ebiom.2019.01.052  0.395
2019 Bertolini I, Terrasi A, Martelli C, Gaudioso G, Di Cristofori A, Storaci AM, Formica M, Braidotti P, Todoerti K, Ferrero S, Caroli M, Ottobrini L, Vaccari T, Vaira V. A GBM-like V-ATPase signature directs cell-cell tumor signaling and reprogramming via large oncosomes. Ebiomedicine. PMID 30737083 DOI: 10.1016/j.ebiom.2019.01.051  0.376
2019 Mastrodonato V, Beznoussenko G, Mironov A, Ferrari L, Deflorian G, Vaccari T. A genetic model of CEDNIK syndrome in zebrafish highlights the role of the SNARE protein Snap29 in neuromotor and epidermal development. Scientific Reports. 9: 1211. PMID 30718891 DOI: 10.1038/s41598-018-37780-4  0.387
2018 Rusmini P, Cortese K, Crippa V, Cristofani R, Cicardi ME, Ferrari V, Vezzoli G, Tedesco B, Meroni M, Messi E, Piccolella M, Galbiati M, Garrè M, Morelli E, Vaccari T, et al. Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration. Autophagy. PMID 30335591 DOI: 10.1080/15548627.2018.1535292  0.394
2018 Alfred V, Vaccari T. Mechanisms of Non-canonical Signaling in Health and Disease: Diversity to Take Therapy up a Notch? Advances in Experimental Medicine and Biology. 1066: 187-204. PMID 30030827 DOI: 10.1007/978-3-319-89512-3_9  0.411
2017 Horner DS, Pasini ME, Beltrame M, Mastrodonato V, Morelli E, Vaccari T. ESCRT genes and regulation of developmental signaling. Seminars in Cell & Developmental Biology. PMID 28847745 DOI: 10.1016/j.semcdb.2017.08.038  0.509
2016 Morelli E, Mastrodonato V, Beznoussenko GV, Mironov AA, Tognon E, Vaccari T. An essential step of kinetochore formation controlled by the SNARE protein Snap29. The Embo Journal. PMID 27647876 DOI: 10.15252/embj.201693991  0.377
2016 Alfred V, Vaccari T. When membranes need an ESCRT: endosomal sorting and membrane remodelling in health and disease. Swiss Medical Weekly. 146: w14347. PMID 27631343 DOI: 10.4414/smw.2016.14347  0.321
2016 Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Vaccari T, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356  0.331
2016 Tognon E, Kobia F, Busi I, Fumagalli A, De Masi F, Vaccari T. Control of lysosomal biogenesis and Notch-dependent tissue patterning by components of the TFEB-V-ATPase axis in Drosophila melanogaster. Autophagy. 0. PMID 26727288 DOI: 10.1080/15548627.2015.1134080  0.391
2015 Di Cristofori A, Ferrero S, Bertolini I, Gaudioso G, Russo MV, Berno V, Vanini M, Locatelli M, Zavanone M, Rampini P, Vaccari T, Caroli M, Vaira V. The vacuolar H+ ATPase is a novel therapeutic target for glioblastoma. Oncotarget. PMID 26020805 DOI: 10.18632/Oncotarget.4239  0.344
2015 Francis K, Duchi S, Vaccari T. V-ATPase inhibition reduces physiologic and oncogenic Notch signaling F1000research. 6. DOI: 10.7490/F1000Research.1097781.1  0.398
2014 Morelli E, Ginefra P, Mastrodonato V, Beznoussenko GV, Rusten TE, Bilder D, Stenmark H, Mironov AA, Vaccari T. Multiple functions of the SNARE protein Snap29 in autophagy, endocytic, and exocytic trafficking during epithelial formation in Drosophila. Autophagy. 10: 2251-68. PMID 25551675 DOI: 10.4161/15548627.2014.981913  0.687
2014 Handschuh K, Feenstra J, Koss M, Ferretti E, Risolino M, Zewdu R, Sahai MA, Bénazet JD, Peng XP, Depew MJ, Quintana L, Sharpe J, Wang B, Alcorn H, Rivi R, ... ... Vaccari T, et al. ESCRT-II/Vps25 constrains digit number by endosome-mediated selective modulation of FGF-SHH signaling. Cell Reports. 9: 674-87. PMID 25373905 DOI: 10.1016/J.Celrep.2014.09.019  0.479
2014 Tognon E, Vaccari T. Immunohistochemical tools and techniques to visualize Notch in Drosophila melanogaster. Methods in Molecular Biology (Clifton, N.J.). 1187: 63-78. PMID 25053481 DOI: 10.1007/978-1-4939-1139-4_5  0.335
2014 Tognon E, Wollscheid N, Cortese K, Tacchetti C, Vaccari T. ESCRT-0 is not required for ectopic Notch activation and tumor suppression in Drosophila. Plos One. 9: e93987. PMID 24718108 DOI: 10.1371/journal.pone.0093987  0.54
2014 Kobia F, Duchi S, Deflorian G, Vaccari T. Pharmacologic inhibition of vacuolar H+ ATPase reduces physiologic and oncogenic Notch signaling. Molecular Oncology. 8: 207-20. PMID 24309677 DOI: 10.1016/j.molonc.2013.11.002  0.506
2013 Petzoldt AG, Gleixner EM, Fumagalli A, Vaccari T, Simons M. Elevated expression of the V-ATPase C subunit triggers JNK-dependent cell invasion and overgrowth in a Drosophila epithelium. Disease Models & Mechanisms. 6: 689-700. PMID 23335205 DOI: 10.1242/dmm.010660  0.457
2013 Petzoldt AG, Gleixner EM, Fumagalli A, Vaccari T, Simons M. Activation of the proton pump, V-ATPase, triggers JNK-dependent cell invasion and overgrowth in a Drosophila epithelium Development. 140. DOI: 10.1242/Dev.094771  0.369
2012 Rusten TE, Vaccari T, Stenmark H. Shaping development with ESCRTs. Nature Cell Biology. 14: 38-45. PMID 22193162 DOI: 10.1038/ncb2381  0.435
2010 Vaccari T, Duchi S, Cortese K, Tacchetti C, Bilder D. The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor. Development (Cambridge, England). 137: 1825-32. PMID 20460366 DOI: 10.1242/dev.045484  0.697
2009 Classen AK, Bunker BD, Harvey KF, Vaccari T, Bilder D. A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling. Nature Genetics. 41: 1150-5. PMID 19749759 DOI: 10.1038/Ng.445  0.652
2009 Vaccari T, Rusten TE, Menut L, Nezis IP, Brech A, Stenmark H, Bilder D. Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants. Journal of Cell Science. 122: 2413-23. PMID 19571114 DOI: 10.1242/jcs.046391  0.656
2009 Vaccari T, Bilder D. At the crossroads of polarity, proliferation and apoptosis: the use of Drosophila to unravel the multifaceted role of endocytosis in tumor suppression. Molecular Oncology. 3: 354-65. PMID 19560990 DOI: 10.1016/j.molonc.2009.05.005  0.673
2008 Vaccari T, Lu H, Kanwar R, Fortini ME, Bilder D. Endosomal entry regulates Notch receptor activation in Drosophila melanogaster. The Journal of Cell Biology. 180: 755-62. PMID 18299346 DOI: 10.1083/Jcb.200708127  0.72
2007 Menut L, Vaccari T, Dionne H, Hill J, Wu G, Bilder D. A mosaic genetic screen for Drosophila neoplastic tumor suppressor genes based on defective pupation. Genetics. 177: 1667-77. PMID 17947427 DOI: 10.1534/genetics.107.078360  0.636
2007 Rusten TE, Vaccari T, Lindmo K, Rodahl LM, Nezis IP, Sem-Jacobsen C, Wendler F, Vincent JP, Brech A, Bilder D, Stenmark H. ESCRTs and Fab1 regulate distinct steps of autophagy. Current Biology : Cb. 17: 1817-25. PMID 17935992 DOI: 10.1016/j.cub.2007.09.032  0.655
2005 Vaccari T, Bilder D. The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking. Developmental Cell. 9: 687-98. PMID 16256743 DOI: 10.1016/j.devcel.2005.09.019  0.701
2005 Vaccari T, Rabouille C, Ephrussi A. The Drosophila PAR-1 spacer domain is required for lateral membrane association and for polarization of follicular epithelial cells. Current Biology : Cb. 15: 255-61. PMID 15694310 DOI: 10.1016/j.cub.2005.01.033  0.624
2002 Vaccari T, Ephrussi A. The fusome and microtubules enrich Par-1 in the oocyte, where it effects polarization in conjunction with Par-3, BicD, Egl, and dynein. Current Biology : Cb. 12: 1524-8. PMID 12225669 DOI: 10.1016/S0960-9822(02)01079-5  0.577
1998 Vaccari T, Beltrame M, Ferrari S, Bianchi ME. Hmg4, a new member of the Hmg1/2 gene family. Genomics. 49: 247-52. PMID 9598312 DOI: 10.1006/geno.1998.5214  0.327
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