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Alex A. Compton, Ph.D. - Publications

Affiliations: 
2008-2012 Molecular and Cellular Biology University of Washington, Seattle, Seattle, WA 
 2013-2016 Virology Institut Pasteur, Paris, Paris, France 
 2017- HIV Dynamics and Replication Program National Cancer Institute/NIH, Bethesda, MD, United States 
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mak NSC, Liu J, Zhang D, Taylor J, Li X, Rahman K, Chen F, Datta SAK, Lai KK, Shi Z, Temperton N, Irving AT, Compton AA, Sloan RD. Alternative splicing expands the antiviral IFITM repertoire in Chinese rufous horseshoe bats. Plos Pathogens. 20: e1012763. PMID 39724110 DOI: 10.1371/journal.ppat.1012763  0.356
2022 Lai KK, Munro JB, Shi G, Majdoul S, Compton AA, Rein A. Restriction of Influenza A Virus by SERINC5. Mbio. e0292322. PMID 36409124 DOI: 10.1128/mbio.02923-22  0.412
2022 Shi G, Chiramel AI, Li T, Lai KK, Kenney AD, Zani A, Eddy AC, Majdoul S, Zhang L, Dempsey T, Beare PA, Kar S, Yewdell JW, Best SM, Yount JS, ... Compton AA, et al. Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2. The Journal of Clinical Investigation. PMID 36264642 DOI: 10.1172/JCI160766  0.365
2021 Majdoul S, Compton AA. Lessons in self-defence: inhibition of virus entry by intrinsic immunity. Nature Reviews. Immunology. PMID 34646033 DOI: 10.1038/s41577-021-00626-8  0.373
2021 Shi G, Chiramel AI, Majdoul S, Lai KK, Das S, Beare PA, Andresson T, Best SM, Compton AA. Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 33880473 DOI: 10.1101/2021.04.15.440067  0.351
2020 Shi G, Kenney AD, Kudryashova E, Zani A, Zhang L, Lai KK, Hall-Stoodley L, Robinson RT, Kudryashov DS, Compton AA, Yount JS. Opposing activities of IFITM proteins in SARS-CoV-2 infection. The Embo Journal. e106501. PMID 33270927 DOI: 10.15252/embj.2020106501  0.344
2020 Rahman K, Coomer CA, Majdoul S, Ding SY, Padilla-Parra S, Compton AA. Homology-guided identification of a conserved motif linking the antiviral functions of IFITM3 to its oligomeric state. Elife. 9. PMID 33112230 DOI: 10.7554/eLife.58537  0.322
2020 Shi G, Kenney AD, Kudryashova E, Zhang L, Hall-Stoodley L, Robinson RT, Kudryashov DS, Compton AA, Yount JS. Opposing activities of IFITM proteins in SARS-CoV-2 infection. Biorxiv : the Preprint Server For Biology. PMID 32803197 DOI: 10.1101/2020.08.11.246678  0.357
2020 Coomer CA, Carlon-Andres I, Iliopoulou M, Dustin ML, Compeer EB, Compton AA, Padilla-Parra S. Single-cell glycolytic activity regulates membrane tension and HIV-1 fusion. Plos Pathogens. 16: e1008359. PMID 32084246 DOI: 10.1371/Journal.Ppat.1008359  0.441
2020 Ahi YS, Yimer D, Shi G, Majdoul S, Rahman K, Rein A, Compton AA. IFITM3 Reduces Retroviral Envelope Abundance and Function and Is Counteracted by glycoGag. Mbio. 11. PMID 31964738 DOI: 10.1128/Mbio.03088-19  0.522
2019 Ozog S, Timberlake ND, Hermann K, Garijo O, Haworth KG, Shi G, Glinkerman CM, Schefter LE, D'Souza S, Simpson E, Sghia-Hughes G, Carillo RR, Boger DL, Kiem HP, Slukvin I, ... ... Compton AA, et al. Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes. Blood. PMID 31416800 DOI: 10.1182/Blood.2019000040  0.311
2018 Shi G, Ozog S, Torbett BE, Compton AA. mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3. Proceedings of the National Academy of Sciences of the United States of America. PMID 30301809 DOI: 10.1073/Pnas.1811892115  0.467
2017 Shi G, Schwartz O, Compton AA. More than meets the I: the diverse antiviral and cellular functions of interferon-induced transmembrane proteins. Retrovirology. 14: 53. PMID 29162141 DOI: 10.1186/S12977-017-0377-Y  0.615
2017 Jakobsdottir GM, Iliopoulou M, Nolan R, Alvarez L, Compton AA, Padilla-Parra S. On the Whereabouts of HIV-1 Cellular Entry and Its Fusion Ports. Trends in Molecular Medicine. PMID 28899754 DOI: 10.1016/J.Molmed.2017.08.005  0.45
2017 Chesarino NM, Compton AA, McMichael TM, Kenney AD, Zhang L, Soewarna V, Davis M, Schwartz O, Yount JS. IFITM3 requires an amphipathic helix for antiviral activity. Embo Reports. PMID 28835547 DOI: 10.15252/Embr.201744100  0.573
2017 Monel B, Compton AA, Bruel T, Amraoui S, Burlaud-Gaillard J, Roy N, Guivel-Benhassine F, Porrot F, Génin P, Meertens L, Sinigaglia L, Jouvenet N, Weil R, Casartelli N, Demangel C, et al. Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells. The Embo Journal. PMID 28473450 DOI: 10.15252/Embj.201695597  0.585
2017 Compton AA, Schwartz O. They Might Be Giants: Does Syncytium Formation Sink or Spread HIV Infection? Plos Pathogens. 13: e1006099. PMID 28152024 DOI: 10.1371/Journal.Ppat.1006099  0.526
2016 Compton AA, Roy N, Porrot F, Billet A, Casartelli N, Yount JS, Liang C, Schwartz O. Natural mutations in IFITM3 modulate post-translational regulation and toggle antiviral specificity. Embo Reports. PMID 27601221 DOI: 10.15252/Embr.201642771  0.634
2016 Zurnic I, Hütter S, Lehmann U, Stanke N, Reh J, Kern T, Lindel F, Gerresheim G, Hamann M, Müllers E, Lesbats P, Cherepanov P, Serrao E, Engelman A, Lindemann D, ... ... Compton A, et al. Proceedings of the Frontiers of Retrovirology Conference 2016 Retrovirology. 13. DOI: 10.1186/S12977-016-0294-5  0.558
2015 Billet A, Compton AA, Schwartz O. The IFITM protein family: Antiviral effects and cellular functions | La famille des protéines IFITM : Effets antiviraux et fonctions cellulaires Virologie. 19: 251-260. DOI: 10.1684/Vir.2015.0625  0.616
2014 Compton AA, Bruel T, Porrot F, Mallet A, Sachse M, Euvrard M, Liang C, Casartelli N, Schwartz O. IFITM proteins incorporated into HIV-1 virions impair viral fusion and spread. Cell Host & Microbe. 16: 736-47. PMID 25464829 DOI: 10.1016/J.Chom.2014.11.001  0.613
2013 Compton AA, Malik HS, Emerman M. Host gene evolution traces the evolutionary history of ancient primate lentiviruses. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 368: 20120496. PMID 23938749 DOI: 10.1098/Rstb.2012.0496  0.603
2013 Compton AA, Emerman M. Convergence and divergence in the evolution of the APOBEC3G-Vif interaction reveal ancient origins of simian immunodeficiency viruses. Plos Pathogens. 9: e1003135. PMID 23359341 DOI: 10.1371/Journal.Ppat.1003135  0.58
2012 Compton AA, Hirsch VM, Emerman M. The host restriction factor APOBEC3G and retroviral Vif protein coevolve due to ongoing genetic conflict. Cell Host & Microbe. 11: 91-8. PMID 22264516 DOI: 10.1016/J.Chom.2011.11.010  0.613
2008 Migueles SA, Osborne CM, Royce C, Compton AA, Joshi RP, Weeks KA, Rood JE, Berkley AM, Sacha JB, Cogliano-Shutta NA, Lloyd M, Roby G, Kwan R, McLaughlin M, Stallings S, et al. Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control. Immunity. 29: 1009-21. PMID 19062316 DOI: 10.1016/J.Immuni.2008.10.010  0.351
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