| Year |
Citation |
Score |
| 2020 |
Chu K, Su Z, Wetter J, Namovic M, Leys L, Wang Y, Honore P, McGaraughty S. Characterization of MC903 induced Atopic Dermatitis‐like skin inflammation in mice The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09550 |
0.532 |
|
| 2018 |
McGaraughty S, Chu KL, Xu J. Characterization and Pharmacological Modulation of Noci-Responsive Deep Dorsal Horn Neurons Across Diverse Rat Models of Pathological Pain. Journal of Neurophysiology. PMID 30067136 DOI: 10.1152/Jn.00325.2018 |
0.692 |
|
| 2018 |
Brederson JD, Chu KL, Xu J, Nikkel AL, Markosyan S, Jarvis MF, Edelmayer R, Bitner RS, McGaraughty S. Characterization and Comparison of Rat Monosodium Iodoacetate and Medial Meniscal Tear Models of Osteoarthritic Pain. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 29430715 DOI: 10.1002/Jor.23869 |
0.683 |
|
| 2017 |
McGaraughty S, Chu KL, Xu J, Leys L, Radek RJ, Dart MJ, Gomtsyan A, Schmidt RG, Kym PR, Brederson JD. TRPV3 modulates nociceptive signaling through peripheral and supraspinal sites in rats. Journal of Neurophysiology. jn.00104.2017. PMID 28468993 DOI: 10.1152/Jn.00104.2017 |
0.742 |
|
| 2015 |
Chu KL, Xu J, Frost J, Li L, Gomez E, Dart MJ, Jarvis MF, Meyer MD, McGaraughty S. A selective α2 B adrenoceptor agonist (A-1262543) and duloxetine modulate nociceptive neurones in the medial prefrontal cortex, but not in the spinal cord of neuropathic rats. European Journal of Pain (London, England). 19: 649-60. PMID 25154730 DOI: 10.1002/ejp.586 |
0.702 |
|
| 2015 |
Jarvis MF, Scott VE, McGaraughty S, Chu KL, Xu J, Niforatos W, Milicic I, Joshi S, Zhang Q, Xia Z. Corrigendum to “A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats” [Biochem. Pharmacol. 89 (4) (2014) 536–544] Biochemical Pharmacology. 94: 227. DOI: 10.1016/J.Bcp.2015.02.008 |
0.624 |
|
| 2014 |
Jarvis MF, Scott VE, McGaraughty S, Chu KL, Xu J, Niforatos W, Milicic I, Joshi S, Zhang Q, Xia Z. A peripherally acting, selective T-type calcium channel blocker, ABT-639, effectively reduces nociceptive and neuropathic pain in rats. Biochemical Pharmacology. 89: 536-44. PMID 24726441 DOI: 10.1016/J.Bcp.2014.03.015 |
0.667 |
|
| 2014 |
Zhu CZ, Vortherms TA, Zhang M, Xu J, Swensen AM, Niforatos W, Neelands T, Milicic I, Lewis LG, Zhong C, Gauvin D, Mikusa J, Zhan C, Pai M, Roderwald V, ... Chu KL, et al. Mechanistic insights into the analgesic efficacy of A-1264087, a novel neuronal Ca(2+) channel blocker that reduces nociception in rat preclinical pain models. The Journal of Pain : Official Journal of the American Pain Society. 15: 387.e1-14. PMID 24374196 DOI: 10.1016/J.Jpain.2013.12.002 |
0.708 |
|
| 2014 |
Xu J, Chu KL, Zhu CZ, Niforatos W, Swensen A, Searle X, Lee L, Jarvis MF, McGaraughty S. A mixed Ca2+ channel blocker, A-1264087, utilizes peripheral and spinal mechanisms to inhibit spinal nociceptive transmission in a rat model of neuropathic pain. Journal of Neurophysiology. 111: 394-404. PMID 24155005 DOI: 10.1152/Jn.00463.2013 |
0.709 |
|
| 2013 |
Leys LJ, Chu KL, Xu J, Pai M, Yang HS, Robb HM, Jarvis MF, Radek RJ, McGaraughty S. Disturbances in slow-wave sleep are induced by models of bilateral inflammation, neuropathic, and postoperative pain, but not osteoarthritic pain in rats. Pain. 154: 1092-102. PMID 23664655 DOI: 10.1016/J.Pain.2013.03.019 |
0.615 |
|
| 2012 |
McGaraughty S, Chu KL, Cowart MD, Brioni JD. Antagonism of supraspinal histamine H3 receptors modulates spinal neuronal activity in neuropathic rats. The Journal of Pharmacology and Experimental Therapeutics. 343: 13-20. PMID 22729221 DOI: 10.1124/jpet.112.194761 |
0.709 |
|
| 2012 |
Xu J, Chu KL, Brederson JD, Jarvis MF, McGaraughty S. Spontaneous firing and evoked responses of spinal nociceptive neurons are attenuated by blockade of P2X3 and P2X2/3 receptors in inflamed rats. Journal of Neuroscience Research. 90: 1597-606. PMID 22422599 DOI: 10.1002/Jnr.23042 |
0.736 |
|
| 2012 |
Brederson JD, Chu KL, Reilly RM, Brown BS, Kym PR, Jarvis MF, McGaraughty S. TRPV1 antagonist, A-889425, inhibits mechanotransmission in a subclass of rat primary afferent neurons following peripheral inflammation. Synapse (New York, N.Y.). 66: 187-95. PMID 21953601 DOI: 10.1002/Syn.20992 |
0.673 |
|
| 2011 |
Chen J, Joshi SK, DiDomenico S, Perner RJ, Mikusa JP, Gauvin DM, Segreti JA, Han P, Zhang XF, Niforatos W, Bianchi BR, Baker SJ, Zhong C, Simler GH, McDonald HA, ... ... Chu KL, et al. Selective blockade of TRPA1 channel attenuates pathological pain without altering noxious cold sensation or body temperature regulation. Pain. 152: 1165-72. PMID 21402443 DOI: 10.1016/J.Pain.2011.01.049 |
0.677 |
|
| 2011 |
Rowbotham MC, Nothaft W, Duan WR, Wang Y, Faltynek C, McGaraughty S, Chu KL, Svensson P. Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial. Pain. 152: 1192-200. PMID 21377273 DOI: 10.1016/J.Pain.2011.01.051 |
0.596 |
|
| 2011 |
Chu KL, Chandran P, Joshi SK, Jarvis MF, Kym PR, McGaraughty S. TRPV1-related modulation of spinal neuronal activity and behavior in a rat model of osteoarthritic pain. Brain Research. 1369: 158-66. PMID 21047496 DOI: 10.1016/j.brainres.2010.10.101 |
0.73 |
|
| 2010 |
Boyce-Rustay JM, Simler GH, McGaraughty S, Chu KL, Wensink EJ, Vasudevan A, Honore P. Characterization of Fasudil in preclinical models of pain. The Journal of Pain : Official Journal of the American Pain Society. 11: 941-9. PMID 20338818 DOI: 10.1016/j.jpain.2009.12.014 |
0.69 |
|
| 2010 |
McGaraughty S, Chu KL, Perner RJ, Didomenico S, Kort ME, Kym PR. TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats. Molecular Pain. 6: 14. PMID 20205719 DOI: 10.1186/1744-8069-6-14 |
0.712 |
|
| 2009 |
McGaraughty S, Chu KL, Dart MJ, Yao BB, Meyer MD. A CB(2) receptor agonist, A-836339, modulates wide dynamic range neuronal activity in neuropathic rats: contributions of spinal and peripheral CB(2) receptors. Neuroscience. 158: 1652-61. PMID 19063946 DOI: 10.1016/j.neuroscience.2008.11.015 |
0.722 |
|
| 2008 |
McGaraughty S, Chu KL, Brown BS, Zhu CZ, Zhong C, Joshi SK, Honore P, Faltynek CR, Jarvis MF. Contributions of central and peripheral TRPV1 receptors to mechanically evoked and spontaneous firing of spinal neurons in inflamed rats. Journal of Neurophysiology. 100: 3158-66. PMID 18829846 DOI: 10.1152/jn.90768.2008 |
0.734 |
|
| 2008 |
Surowy CS, Neelands TR, Bianchi BR, McGaraughty S, El Kouhen R, Han P, Chu KL, McDonald HA, Vos M, Niforatos W, Bayburt EK, Gomtsyan A, Lee CH, Honore P, Sullivan JP, et al. (R)-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)-urea (ABT-102) blocks polymodal activation of transient receptor potential vanilloid 1 receptors in vitro and heat-evoked firing of spinal dorsal horn neurons in vivo. The Journal of Pharmacology and Experimental Therapeutics. 326: 879-88. PMID 18515644 DOI: 10.1124/Jpet.108.138511 |
0.724 |
|
| 2008 |
McGaraughty S, Chu KL, Scanio MJ, Kort ME, Faltynek CR, Jarvis MF. A selective Nav1.8 sodium channel blocker, A-803467 [5-(4-chlorophenyl-N-(3,5-dimethoxyphenyl)furan-2-carboxamide], attenuates spinal neuronal activity in neuropathic rats. The Journal of Pharmacology and Experimental Therapeutics. 324: 1204-11. PMID 18089840 DOI: 10.1124/jpet.107.134148 |
0.715 |
|
| 2007 |
Jarvis MF, Honore P, Shieh CC, Chapman M, Joshi S, Zhang XF, Kort M, Carroll W, Marron B, Atkinson R, Thomas J, Liu D, Krambis M, Liu Y, McGaraughty S, ... Chu K, et al. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proceedings of the National Academy of Sciences of the United States of America. 104: 8520-5. PMID 17483457 DOI: 10.1073/Pnas.0611364104 |
0.705 |
|
| 2007 |
McGaraughty S, Chu KL, Namovic MT, Donnelly-Roberts DL, Harris RR, Zhang XF, Shieh CC, Wismer CT, Zhu CZ, Gauvin DM, Fabiyi AC, Honore P, Gregg RJ, Kort ME, Nelson DW, et al. P2X7-related modulation of pathological nociception in rats. Neuroscience. 146: 1817-28. PMID 17478048 DOI: 10.1016/j.neuroscience.2007.03.035 |
0.75 |
|
| 2006 |
El-Kouhen O, Lehto SG, Pan JB, Chang R, Baker SJ, Zhong C, Hollingsworth PR, Mikusa JP, Cronin EA, Chu KL, McGaraughty SP, Uchic ME, Miller LN, Rodell NM, Patel M, et al. Blockade of mGluR1 receptor results in analgesia and disruption of motor and cognitive performances: effects of A-841720, a novel non-competitive mGluR1 receptor antagonist. British Journal of Pharmacology. 149: 761-74. PMID 17016515 DOI: 10.1038/sj.bjp.0706877 |
0.702 |
|
| 2006 |
McGaraughty S, Chu KL, Faltynek CR, Jarvis MF. Systemic and site-specific effects of A-425619, a selective TRPV1 receptor antagonist, on wide dynamic range neurons in CFA-treated and uninjured rats. Journal of Neurophysiology. 95: 18-25. PMID 16162831 DOI: 10.1152/jn.00560.2005 |
0.708 |
|
| 2004 |
Chu KL, Faltynek CR, Jarvis MF, McGaraughty S. Increased WDR spontaneous activity and receptive field size in rats following a neuropathic or inflammatory injury: implications for mechanical sensitivity. Neuroscience Letters. 372: 123-6. PMID 15531101 DOI: 10.1016/j.neulet.2004.09.025 |
0.656 |
|
| 2003 |
McGaraughty S, Wismer CT, Zhu CZ, Mikusa J, Honore P, Chu KL, Lee CH, Faltynek CR, Jarvis MF. Effects of A-317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration. British Journal of Pharmacology. 140: 1381-8. PMID 14623769 DOI: 10.1038/sj.bjp.0705574 |
0.696 |
|
| 2003 |
Zheng GZ, Mao Y, Lee CH, Pratt JK, Koenig JR, Perner RJ, Cowart MD, Gfesser GA, McGaraughty S, Chu KL, Zhu C, Yu H, Kohlhaas K, Alexander KM, Wismer CT, et al. Adenosine kinase inhibitors: polar 7-substitutent of pyridopyrimidine derivatives improving their locomotor selectivity. Bioorganic & Medicinal Chemistry Letters. 13: 3041-4. PMID 12941329 DOI: 10.1016/S0960-894X(03)00642-5 |
0.596 |
|
| 2003 |
McGaraughty S, Chu KL, Bitner RS, Martino B, El Kouhen R, Han P, Nikkel AL, Burgard EC, Faltynek CR, Jarvis MF. Capsaicin infused into the PAG affects rat tail flick responses to noxious heat and alters neuronal firing in the RVM. Journal of Neurophysiology. 90: 2702-10. PMID 12815018 DOI: 10.1152/Jn.00433.2003 |
0.669 |
|
| 2002 |
Jarvis MF, Burgard EC, McGaraughty S, Honore P, Lynch K, Brennan TJ, Subieta A, Van Biesen T, Cartmell J, Bianchi B, Niforatos W, Kage K, Yu H, Mikusa J, Wismer CT, ... ... Chu K, et al. A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat. Proceedings of the National Academy of Sciences of the United States of America. 99: 17179-84. PMID 12482951 DOI: 10.1073/Pnas.252537299 |
0.716 |
|
| 2002 |
Jarvis MF, Mikusa J, Chu KL, Wismer CT, Honore P, Kowaluk EA, McGaraughty S. Comparison of the ability of adenosine kinase inhibitors and adenosine receptor agonists to attenuate thermal hyperalgesia and reduce motor performance in rats. Pharmacology, Biochemistry, and Behavior. 73: 573-81. PMID 12151032 DOI: 10.1016/S0091-3057(02)00840-7 |
0.641 |
|
| 2002 |
Jarvis MF, Yu H, McGaraughty S, Wismer CT, Mikusa J, Zhu C, Chu K, Kohlhaas K, Cowart M, Lee CH, Stewart AO, Cox BF, Polakowski J, Kowaluk EA. Analgesic and anti-inflammatory effects of A-286501, a novel orally active adenosine kinase inhibitor. Pain. 96: 107-18. PMID 11932067 DOI: 10.1016/S0304-3959(01)00435-3 |
0.679 |
|
| 2001 |
Zheng GZ, Lee C, Pratt JK, Perner RJ, Jiang MQ, Gomtsyan A, Matulenko MA, Mao Y, Koenig JR, Kim KH, Muchmore S, Yu H, Kohlhaas K, Alexander KM, McGaraughty S, ... Chu KL, et al. Pyridopyrimidine analogues as novel adenosine kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 11: 2071-4. PMID 11514141 DOI: 10.1016/S0960-894X(01)00375-4 |
0.562 |
|
| 2001 |
Zhu CZ, Mikusa J, Chu KL, Cowart M, Kowaluk EA, Jarvis MF, McGaraughty S. A-134974: a novel adenosine kinase inhibitor, relieves tactile allodynia via spinal sites of action in peripheral nerve injured rats. Brain Research. 905: 104-10. PMID 11423084 DOI: 10.1016/S0006-8993(01)02512-4 |
0.697 |
|
| 2001 |
McGaraughty S, Chu KL, Wismer CT, Mikusa J, Zhu CZ, Cowart M, Kowaluk EA, Jarvis MF. Effects of A-134974, a novel adenosine kinase inhibitor, on carrageenan-induced inflammatory hyperalgesia and locomotor activity in rats: evaluation of the sites of action. The Journal of Pharmacology and Experimental Therapeutics. 296: 501-9. PMID 11160637 |
0.639 |
|
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