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Rachael W. Sirianni, Ph.D. - Publications

Affiliations: 
2008 Yale University, New Haven, CT 
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bell L, Fuentes AE, Healey DR, Chao R, Bakkar N, Sirianni RW, Medina DX, Bowser RP, Ladha SS, Semmineh NB, Stokes AM, Quarles CC. Longitudinal evaluation of myofiber microstructural changes in a preclinical ALS model using the transverse relaxivity at tracer equilibrium (TRATE): A preliminary study. Magnetic Resonance Imaging. PMID 34715291 DOI: 10.1016/j.mri.2021.10.036  0.655
2021 Chaudhuri S, Fowler MJ, Baker C, Stopka SA, Regan MS, Sablatura L, Broughton CW, Knight BE, Stabenfeldt SE, Agar NYR, Sirianni RW. β-Cyclodextrin-poly (β-Amino Ester) Nanoparticles Are a Generalizable Strategy for High Loading and Sustained Release of HDAC Inhibitors. Acs Applied Materials & Interfaces. PMID 33905245 DOI: 10.1021/acsami.0c22587  0.38
2020 Prakapenka AV, Quihuis AM, Carson CG, Patel S, Bimonte-Nelson HA, Sirianni RW. Poly(lactic-co-glycolic Acid) Nanoparticle Encapsulated 17β-Estradiol Improves Spatial Memory and Increases Uterine Stimulation in Middle-Aged Ovariectomized Rats. Frontiers in Behavioral Neuroscience. 14: 597690. PMID 33424559 DOI: 10.3389/fnbeh.2020.597690  0.781
2020 Prakapenka AV, Peña VL, Strouse I, Northup-Smith S, Schrier A, Ahmed K, Bimonte-Nelson HA, Sirianni RW. Intranasal 17β-Estradiol Modulates Spatial Learning and Memory in a Rat Model of Surgical Menopause. Pharmaceutics. 12. PMID 33348722 DOI: 10.3390/pharmaceutics12121225  0.756
2020 Medina DX, Chung EP, Teague CD, Bowser R, Sirianni RW. Intravenously Administered, Retinoid Activating Nanoparticles Increase Lifespan and Reduce Neurodegeneration in the SOD1 Mouse Model of ALS. Frontiers in Bioengineering and Biotechnology. 8: 224. PMID 32292776 DOI: 10.3389/Fbioe.2020.00224  0.73
2020 Fowler MJ, Cotter JD, Knight BE, Sevick-Muraca EM, Sandberg DI, Sirianni RW. Intrathecal drug delivery in the era of nanomedicine. Advanced Drug Delivery Reviews. PMID 32142739 DOI: 10.1016/J.Addr.2020.02.006  0.44
2020 Chung EP, Cotter JD, Prakapenka AV, Cook RL, DiPerna DM, Sirianni RW. Targeting Small Molecule Delivery to the Brain and Spinal Cord via Intranasal Administration of Rabies Virus Glycoprotein (RVG29)-Modified PLGA Nanoparticles. Pharmaceutics. 12. PMID 31991664 DOI: 10.3390/Pharmaceutics12020093  0.787
2019 Householder KT, Dharmaraj S, Sandberg DI, Wechsler-Reya RJ, Sirianni RW. Fate of nanoparticles in the central nervous system after intrathecal injection in healthy mice. Scientific Reports. 9: 12587. PMID 31467368 DOI: 10.1038/S41598-019-49028-W  0.404
2019 Medina DX, Chung EP, Bowser R, Sirianni RW. Lipid and polymer blended polyester nanoparticles loaded with adapalene for activation of retinoid signaling in the CNS following intravenous administration Journal of Drug Delivery Science and Technology. 52: 927-933. DOI: 10.1016/J.Jddst.2019.04.013  0.757
2018 DiPerna DM, Prakapenka AV, Chung EP, Sirianni RW. Non-Enzymatic Tissue Homogenization for Biodistribution Analysis. Methods in Molecular Biology (Clifton, N.J.). 1831: 191-199. PMID 30051433 DOI: 10.1007/978-1-4939-8661-3_14  0.755
2018 Householder KT, DiPerna DM, Chung EP, Luning AR, Nguyen DT, Stabenfeldt SE, Mehta S, Sirianni RW. pH driven precipitation of quisinostat onto PLA-PEG nanoparticles enables treatment of intracranial glioblastoma. Colloids and Surfaces. B, Biointerfaces. 166: 37-44. PMID 29533842 DOI: 10.1016/J.Colsurfb.2018.02.048  0.385
2017 Prakapenka AV, Hiroi R, Quihuis AM, Carson C, Patel S, Berns-Leone C, Fox C, Sirianni RW, Bimonte-Nelson HA. Contrasting effects of individual versus combined estrogen and progestogen regimens as working memory load increases in middle-aged ovariectomized rats: one plus one does not equal two. Neurobiology of Aging. 64: 1-14. PMID 29316527 DOI: 10.1016/J.Neurobiolaging.2017.11.015  0.735
2017 Prakapenka AV, Bimonte-Nelson HA, Sirianni RW. Engineering poly(lactic-co-glycolic acid) (PLGA) micro- and nano-carriers for Controlled Delivery of 17β-Estradiol. Annals of Biomedical Engineering. PMID 28634732 DOI: 10.1007/S10439-017-1859-8  0.759
2017 Medina DX, Householder KT, Ceton R, Kovalik T, Heffernan JM, Shankar RV, Bowser RP, Wechsler-Reya RJ, Sirianni RW. Optical barcoding of PLGA for multispectral analysis of nanoparticle fate in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28263836 DOI: 10.1016/J.Jconrel.2017.02.033  0.749
2017 Prakapenka AV, Quihuis AM, Hiroi R, Carson CG, Patel S, Chung E, DiPerna DM, Bimonte-Nelson HA, Sirianni RW. Delivery of 17β-estradiol using poly(lactic-co-glycolic acid) nanoparticles for cognitive therapy in a model of surgical menopause Experimental Gerontology. 94: 112. DOI: 10.1016/J.Exger.2017.02.022  0.666
2016 Kobes JE, Daryaei I, Howison CM, Bontrager JG, Sirianni RW, Meuillet EJ, Pagel MD. Improved Treatment of Pancreatic Cancer With Drug Delivery Nanoparticles Loaded With a Novel AKT/PDK1 Inhibitor. Pancreas. PMID 26918875 DOI: 10.1097/Mpa.0000000000000607  0.434
2016 Householder KT, DiPerna D, Ghaffari L, Sirianni R. Abstract 1314: Evaluating payload delivery to the CNS from surface-modified nanoparticles Cancer Research. 76: 1314-1314. DOI: 10.1158/1538-7445.Am2016-1314  0.492
2016 Householder KT, Chung EP, Enns J, Sirianni R. EXTH-61. NANOPARTICLE DELIVERY TO THE SPINAL CORD VIA DIRECT ADMINISTRATION TO CEREBROSPINAL FLUID Neuro-Oncology. 18: vi72-vi72. DOI: 10.1093/Neuonc/Now212.303  0.371
2015 Cook RL, Householder KT, Chung EP, Prakapenka AV, DiPerna DM, Sirianni RW. A critical evaluation of drug delivery from ligand modified nanoparticles: Confounding small molecule distribution and efficacy in the central nervous system. Journal of Controlled Release : Official Journal of the Controlled Release Society. 220: 89-97. PMID 26471392 DOI: 10.1016/J.Jconrel.2015.10.013  0.79
2015 Householder KT, DiPerna DM, Chung EP, Wohlleb GM, Dhruv HD, Berens ME, Sirianni RW. Intravenous delivery of camptothecin-loaded PLGA nanoparticles for the treatment of intracranial glioma. International Journal of Pharmaceutics. 479: 374-80. PMID 25562639 DOI: 10.1016/J.Ijpharm.2015.01.002  0.446
2015 Householder KT, DiPerna DM, Yamaguchi JT, Sanai N, Mehta S, Sirianni RW. Abstract B21: Use of polymeric nanoparticles for the delivery of YM155 to glioma cells in vitro and in vivo Brain. 75. DOI: 10.1158/1538-7445.Brain15-B21  0.434
2014 McCall RL, Cacaccio J, Wrabel E, Schwartz ME, Coleman TP, Sirianni RW. Pathogen-inspired drug delivery to the central nervous system. Tissue Barriers. 2: e944449. PMID 25610755 DOI: 10.4161/21688362.2014.944449  0.345
2014 Sirianni RW, Zheng MQ, Patel TR, Shafbauer T, Zhou J, Saltzman WM, Carson RE, Huang Y. Radiolabeling of poly(lactic-co-glycolic acid) (PLGA) nanoparticles with biotinylated F-18 prosthetic groups and imaging of their delivery to the brain with positron emission tomography. Bioconjugate Chemistry. 25: 2157-65. PMID 25322194 DOI: 10.1021/Bc500315J  0.586
2014 McCall RL, Householder KT, Chung EP, Sirianni RW. Abstract 4579: Pathogen-derived targets for the delivery of chemotherapeutics to the brain Cancer Research. 74: 4579-4579. DOI: 10.1158/1538-7445.Am2014-4579  0.474
2013 McCall RL, Sirianni RW. PLGA nanoparticles formed by single- or double-emulsion with vitamin E-TPGS. Journal of Visualized Experiments : Jove. 51015. PMID 24429733 DOI: 10.3791/51015  0.455
2013 Zhou J, Patel TR, Sirianni RW, Strohbehn G, Zheng MQ, Duong N, Schafbauer T, Huttner AJ, Huang Y, Carson RE, Zhang Y, Sullivan DJ, Piepmeier JM, Saltzman WM. Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 110: 11751-6. PMID 23818631 DOI: 10.1073/Pnas.1304504110  0.603
2013 Sirianni RW, Zheng MQ, Saltzman WM, Huang Y, Carson RE. Direct, quantitative, and noninvasive imaging of the transport of active agents through intact brain with positron emission tomography. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 15: 596-605. PMID 23624949 DOI: 10.1007/S11307-013-0636-9  0.528
2013 Aaberg-Jessen C, Fogh L, Halle B, Jensen V, Brunner N, Kristensen BW, Abe T, Momii Y, Watanabe J, Morisaki I, Natsume A, Wakabayashi T, Fujiki M, Aldaz B, Fabius AWM, ... ... Sirianni RW, et al. EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY Neuro-Oncology. 15: iii37-iii61. DOI: 10.1093/Neuonc/Not176  0.386
2010 Sirianni RW, Olausson P, Chiu AS, Taylor JR, Saltzman WM. The behavioral and biochemical effects of BDNF containing polymers implanted in the hippocampus of rats. Brain Research. 1321: 40-50. PMID 20096671 DOI: 10.1016/J.Brainres.2010.01.041  0.499
2010 Sirianni RW, Jang EH, Miller KM, Saltzman WM. Parameter estimation methodology in a model of hydrophobic drug release from a polymer coating. Journal of Controlled Release : Official Journal of the Controlled Release Society. 142: 474-82. PMID 19958804 DOI: 10.1016/J.Jconrel.2009.11.021  0.498
2008 Sirianni RW, Kremer J, Guler I, Chen YL, Keeley FW, Saltzman WM. Effect of extracellular matrix elements on the transport of paclitaxel through an arterial wall tissue mimic. Biomacromolecules. 9: 2792-8. PMID 18785771 DOI: 10.1021/Bm800571S  0.478
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