Phillip D. Zamore, Ph.D. - Publications

University of Massachusetts Medical School, Worcester, MA, United States 
RNA interference, RNAi, microRNAs, piRNAs, transposons

148 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Yu T, Fan K, Özata DM, Zhang G, Fu Y, Theurkauf WE, Zamore PD, Weng Z. Long first exons and epigenetic marks distinguish conserved pachytene piRNA clusters from other mammalian genes. Nature Communications. 12: 73. PMID 33397987 DOI: 10.1038/s41467-020-20345-3  0.32
2020 Wu PH, Fu Y, Cecchini K, Özata DM, Arif A, Yu T, Colpan C, Gainetdinov I, Weng Z, Zamore PD. The evolutionarily conserved piRNA-producing locus pi6 is required for male mouse fertility. Nature Genetics. PMID 32601478 DOI: 10.1038/S41588-020-0657-7  0.36
2020 Özata DM, Yu T, Mou H, Gainetdinov I, Colpan C, Cecchini K, Kaymaz Y, Wu PH, Fan K, Kucukural A, Weng Z, Zamore PD. Evolutionarily conserved pachytene piRNA loci are highly divergent among modern humans. Nature Ecology & Evolution. 4: 156-168. PMID 31900453 DOI: 10.1038/S41559-019-1065-1  0.36
2019 Xie J, Tai PWL, Brown A, Gong S, Zhu S, Wang Y, Li C, Colpan C, Su Q, He R, Ma H, Li J, Ye H, Ko J, Zamore PD, et al. Effective and Accurate Gene Silencing by a Recombinant AAV-Compatible MicroRNA Scaffold. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31843447 DOI: 10.1016/J.Ymthe.2019.11.018  0.36
2019 Ge DT, Wang W, Tipping C, Gainetdinov I, Weng Z, Zamore PD. The RNA-Binding ATPase, Armitage, Couples piRNA Amplification in Nuage to Phased piRNA Production on Mitochondria. Molecular Cell. PMID 31076285 DOI: 10.1016/J.Molcel.2019.04.006  0.32
2019 Li C, Zamore PD. RNA Interference and Small RNA Analysis. Cold Spring Harbor Protocols. 2019: pdb.top097436. PMID 30936388 DOI: 10.1101/pdb.top097436  0.36
2019 Li C, Zamore PD. RNAi in S2 Cells by siRNA Duplex or dsRNA Transfection. Cold Spring Harbor Protocols. 2019: pdb.prot097485. PMID 30936384 DOI: 10.1101/pdb.prot097485  0.36
2019 Li C, Zamore PD. RNAi in Mammalian Cells by siRNA Duplex Transfection. Cold Spring Harbor Protocols. 2019: pdb.prot097451. PMID 30936383 DOI: 10.1101/pdb.prot097451  0.36
2019 Li C, Zamore PD. Preparation of siRNA Duplexes. Cold Spring Harbor Protocols. 2019: pdb.prot097444. PMID 30936382 DOI: 10.1101/pdb.prot097444  0.36
2019 Li C, Zamore PD. RNAi in S2 Cells by dsRNA Soaking. Cold Spring Harbor Protocols. 2019: pdb.prot097477. PMID 30824620 DOI: 10.1101/pdb.prot097477  0.36
2019 Li C, Zamore PD. Preparation of dsRNAs for RNAi by In Vitro Transcription. Cold Spring Harbor Protocols. 2019: pdb.prot097469. PMID 30824619 DOI: 10.1101/pdb.prot097469  0.36
2018 Chang TH, Mattei E, Gainetdinov I, Colpan C, Weng Z, Zamore PD. Maelstrom Represses Canonical Polymerase II Transcription within Bi-directional piRNA Clusters in Drosophila melanogaster. Molecular Cell. PMID 30527661 DOI: 10.1016/J.Molcel.2018.10.038  0.36
2018 Gainetdinov I, Colpan C, Arif A, Cecchini K, Zamore PD. A Single Mechanism of Biogenesis, Initiated and Directed by PIWI Proteins, Explains piRNA Production in Most Animals. Molecular Cell. 71: 775-790.e5. PMID 30193099 DOI: 10.1016/j.molcel.2018.08.007  0.36
2018 Li C, Zamore PD. Analysis of Small RNAs by Northern Hybridization. Cold Spring Harbor Protocols. 2018: pdb.prot097493. PMID 30068587 DOI: 10.1101/pdb.prot097493  0.36
2018 Fu Y, Wu PH, Beane T, Zamore PD, Weng Z. Elimination of PCR duplicates in RNA-seq and small RNA-seq using unique molecular identifiers. Bmc Genomics. 19: 531. PMID 30001700 DOI: 10.1186/S12864-018-4933-1  0.32
2018 Li C, Zamore PD. Inhibiting miRNA Function by Antisense Oligonucleotides in Drosophila S2 Cells. Cold Spring Harbor Protocols. 2018: pdb.prot097543. PMID 29438062 DOI: 10.1101/pdb.prot097543  0.36
2018 Li C, Zamore PD. Inhibiting miRNA Function by Antisense Oligonucleotides in Cultured Mammalian Cells. Cold Spring Harbor Protocols. 2018: pdb.prot097535. PMID 29438061 DOI: 10.1101/pdb.prot097535  0.36
2018 Li C, Zamore PD. Preparation of Antisense Oligonucleotides to Inhibit miRNA Function. Cold Spring Harbor Protocols. 2018: pdb.prot097527. PMID 29438060 DOI: 10.1101/pdb.prot097527  0.36
2018 Fu Y, Yang Y, Zhang H, Farley G, Wang J, Quarles KA, Weng Z, Zamore PD. The genome of the Hi5 germ cell line from Trichoplusia ni, an agricultural pest and novel model for small RNA biology. Elife. 7. PMID 29376823 DOI: 10.7554/Elife.31628  0.32
2017 Fu Y, Yang Y, Zhang H, Farley G, Wang J, Quarles KA, Weng Z, Zamore PD. Author response: The genome of the Hi5 germ cell line from Trichoplusia ni, an agricultural pest and novel model for small RNA biology Elife. DOI: 10.7554/Elife.31628.041  0.32
2015 Wang W, Han BW, Tipping C, Ge DT, Zhang Z, Weng Z, Zamore PD. Slicing and Binding by Ago3 or Aub Trigger Piwi-Bound piRNA Production by Distinct Mechanisms. Molecular Cell. 59: 819-30. PMID 26340424 DOI: 10.1016/J.Molcel.2015.08.007  1
2015 Chou MT, Han BW, Hsiao CP, Zamore PD, Weng Z, Hung JH. Tailor: a computational framework for detecting non-templated tailing of small silencing RNAs. Nucleic Acids Research. PMID 26007652 DOI: 10.1093/Nar/Gkv537  0.36
2015 Han BW, Wang W, Li C, Weng Z, Zamore PD. Noncoding RNA. piRNA-guided transposon cleavage initiates Zucchini-dependent, phased piRNA production. Science (New York, N.Y.). 348: 817-21. PMID 25977554 DOI: 10.1126/Science.Aaa1264  1
2015 Marinov GK, Wang J, Handler D, Wold BJ, Weng Z, Hannon GJ, Aravin AA, Zamore PD, Brennecke J, Toth KF. Pitfalls of mapping high-throughput sequencing data to repetitive sequences: Piwi's genomic targets still not identified. Developmental Cell. 32: 765-71. PMID 25805138 DOI: 10.1016/J.Devcel.2015.01.013  1
2015 Han BW, Wang W, Zamore PD, Weng Z. piPipes: a set of pipelines for piRNA and transposon analysis via small RNA-seq, RNA-seq, degradome- and CAGE-seq, ChIP-seq and genomic DNA sequencing. Bioinformatics (Oxford, England). 31: 593-5. PMID 25342065 DOI: 10.1093/Bioinformatics/Btu647  1
2015 Salomon WE, Jolly SM, Moore MJ, Zamore PD, Serebrov V. Single-Molecule Imaging Reveals that Argonaute Reshapes the Binding Properties of Its Nucleic Acid Guides Cell. 162: 84-95. DOI: 10.1016/j.cell.2015.06.029  1
2014 Wang W, Yoshikawa M, Han BW, Izumi N, Tomari Y, Weng Z, Zamore PD. The initial uridine of primary piRNAs does not create the tenth adenine that Is the hallmark of secondary piRNAs. Molecular Cell. 56: 708-16. PMID 25453759 DOI: 10.1016/J.Molcel.2014.10.016  1
2014 Han BW, Zamore PD. piRNAs. Current Biology : Cb. 24: R730-3. PMID 25137579 DOI: 10.1016/j.cub.2014.07.037  1
2014 Babcock GJ, Iyer S, Smith HL, Wang Y, Rowley K, Ambrosino DM, Zamore PD, Pierce BG, Molrine DC, Weng Z. High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody. Plos One. 9: e100325. PMID 24956119 DOI: 10.1371/Journal.Pone.0100325  1
2014 Zhang Z, Wang J, Schultz N, Zhang F, Parhad SS, Tu S, Vreven T, Zamore PD, Weng Z, Theurkauf WE. The HP1 homolog rhino anchors a nuclear complex that suppresses piRNA precursor splicing. Cell. 157: 1353-63. PMID 24906152 DOI: 10.1016/J.Cell.2014.04.030  1
2014 Broderick JA, Zamore PD. Competitive endogenous RNAs cannot alter microRNA function in vivo. Molecular Cell. 54: 711-3. PMID 24905003 DOI: 10.1016/j.molcel.2014.05.023  1
2014 Fukunaga R, Zamore PD. A universal small molecule, inorganic phosphate, restricts the substrate specificity of Dicer-2 in small RNA biogenesis. Cell Cycle (Georgetown, Tex.). 13: 1671-6. PMID 24787225 DOI: 10.4161/Cc.29066  1
2014 Zhang Z, Koppetsch BS, Wang J, Tipping C, Weng Z, Theurkauf WE, Zamore PD. Antisense piRNA amplification, but not piRNA production or nuage assembly, requires the Tudor-domain protein Qin. The Embo Journal. 33: 536-9. PMID 24652836 DOI: 10.1002/Embj.201384895  1
2014 Moran Y, Fredman D, Praher D, Li XZ, Wee LM, Rentzsch F, Zamore PD, Technau U, Seitz H. Cnidarian microRNAs frequently regulate targets by cleavage. Genome Research. 24: 651-63. PMID 24642861 DOI: 10.1101/Gr.162503.113  1
2014 Fukunaga R, Colpan C, Han BW, Zamore PD. Inorganic phosphate blocks binding of pre-miRNA to Dicer-2 via its PAZ domain. The Embo Journal. 33: 371-84. PMID 24488111 DOI: 10.1002/Embj.201387176  1
2014 Babcock GJ, Iyer S, Smith HL, Wang Y, Rowley K, Ambrosino DM, Zamore PD, Pierce BG, Molrine DC, Weng Z. Changes in viral loads and epitope sequence distributions in placebo subjects. Plos One. DOI: 10.1371/Journal.Pone.0100325.G002  0.32
2013 Liu W, Chaurette J, Pfister EL, Kennington LA, Chase KO, Bullock J, Vonsattel JP, Faull RL, Macdonald D, DiFiglia M, Zamore PD, Aronin N. Increased Steady-State Mutant Huntingtin mRNA in Huntington's Disease Brain. Journal of Huntington's Disease. 2: 491-500. PMID 25062733 DOI: 10.3233/Jhd-130079  1
2013 Ameres SL, Zamore PD. Diversifying microRNA sequence and function. Nature Reviews. Molecular Cell Biology. 14: 475-88. PMID 23800994 DOI: 10.1038/nrm3611  1
2013 Ge DT, Zamore PD. Small RNA-directed silencing: the fly finds its inner fission yeast? Current Biology : Cb. 23: R318-20. PMID 23618667 DOI: 10.1016/j.cub.2013.03.033  1
2013 Li XZ, Roy CK, Dong X, Bolcun-Filas E, Wang J, Han BW, Xu J, Moore MJ, Schimenti JC, Weng Z, Zamore PD. An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes. Molecular Cell. 50: 67-81. PMID 23523368 DOI: 10.1016/J.Molcel.2013.02.016  0.36
2013 Chung RT, Gordon FD, Curry MP, Schiano TD, Emre S, Corey K, Markmann JF, Hertl M, Pomposelli JJ, Pomfret EA, Florman S, Schilsky M, Broering TJ, Finberg RW, Szabo G, ... Zamore PD, et al. Human monoclonal antibody MBL-HCV1 delays HCV viral rebound following liver transplantation: a randomized controlled study. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 13: 1047-54. PMID 23356386 DOI: 10.1111/Ajt.12083  1
2013 Flores-Jasso CF, Salomon WE, Zamore PD. Rapid and specific purification of Argonaute-small RNA complexes from crude cell lysates. Rna (New York, N.Y.). 19: 271-9. PMID 23249751 DOI: 10.1261/rna.036921.112  1
2012 Fukunaga R, Han BW, Hung JH, Xu J, Weng Z, Zamore PD. Dicer Partner Proteins Tune the Length of Mature miRNAs in Flies and Mammals. Cell. 151: 912. PMID 30360291 DOI: 10.1016/J.Cell.2012.10.029  1
2012 Zhang Z, Theurkauf WE, Weng Z, Zamore PD. Strand-specific libraries for high throughput RNA sequencing (RNA-Seq) prepared without poly(A) selection. Silence. 3: 9. PMID 23273270 DOI: 10.1186/1758-907X-3-9  1
2012 Wee LM, Flores-Jasso CF, Salomon WE, Zamore PD. Argonaute divides its RNA guide into domains with distinct functions and RNA-binding properties. Cell. 151: 1055-67. PMID 23178124 DOI: 10.1016/j.cell.2012.10.036  1
2012 Zhang F, Wang J, Xu J, Zhang Z, Koppetsch BS, Schultz N, Vreven T, Meignin C, Davis I, Zamore PD, Weng Z, Theurkauf WE. UAP56 couples piRNA clusters to the perinuclear transposon silencing machinery. Cell. 151: 871-84. PMID 23141543 DOI: 10.1016/J.Cell.2012.09.040  1
2012 Fukunaga R, Han BW, Hung JH, Xu J, Weng Z, Zamore PD. Dicer partner proteins tune the length of mature miRNAs in flies and mammals. Cell. 151: 533-46. PMID 23063653 DOI: 10.1016/J.Cell.2012.09.027  1
2012 Zamore PD. RNA: methods and protocols - a new series. Silence. 3: 7. PMID 22676652 DOI: 10.1186/1758-907X-3-7  1
2012 Xie J, Ameres SL, Friedline R, Hung JH, Zhang Y, Xie Q, Zhong L, Su Q, He R, Li M, Li H, Mu X, Zhang H, Broderick JA, Kim JK, ... ... Zamore PD, et al. Long-term, efficient inhibition of microRNA function in mice using rAAV vectors. Nature Methods. 9: 403-9. PMID 22388288 DOI: 10.1038/Nmeth.1903  1
2012 Mueller C, Tang Q, Gruntman A, Blomenkamp K, Teckman J, Song L, Zamore PD, Flotte TR. Sustained miRNA-mediated knockdown of mutant AAT with simultaneous augmentation of wild-type AAT has minimal effect on global liver miRNA profiles. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 590-600. PMID 22252449 DOI: 10.1038/mt.2011.292  1
2012 Fukunaga R, Zamore PD. Loquacious, a Dicer Partner Protein, Functions in Both the MicroRNA and siRNA Pathways Enzymes. 32: 37-68. DOI: 10.1016/B978-0-12-404741-9.00002-7  1
2011 Khurana JS, Wang J, Xu J, Koppetsch BS, Thomson TC, Nowosielska A, Li C, Zamore PD, Weng Z, Theurkauf WE. Adaptation to P element transposon invasion in Drosophila melanogaster. Cell. 147: 1551-63. PMID 22196730 DOI: 10.1016/J.Cell.2011.11.042  1
2011 Zhang Z, Xu J, Koppetsch BS, Wang J, Tipping C, Ma S, Weng Z, Theurkauf WE, Zamore PD. Heterotypic piRNA Ping-Pong requires qin, a protein with both E3 ligase and Tudor domains. Molecular Cell. 44: 572-84. PMID 22099305 DOI: 10.1016/J.Molcel.2011.10.011  1
2011 Han BW, Hung JH, Weng Z, Zamore PD, Ameres SL. The 3'-to-5' exoribonuclease Nibbler shapes the 3' ends of microRNAs bound to Drosophila Argonaute1. Current Biology : Cb. 21: 1878-87. PMID 22055293 DOI: 10.1016/J.Cub.2011.09.034  1
2011 Broderick JA, Salomon WE, Ryder SP, Aronin N, Zamore PD. Argonaute protein identity and pairing geometry determine cooperativity in mammalian RNA silencing. Rna (New York, N.Y.). 17: 1858-69. PMID 21878547 DOI: 10.1261/Rna.2778911  1
2011 Cenik ES, Zamore PD. Argonaute proteins. Current Biology : Cb. 21: R446-9. PMID 21683893 DOI: 10.1016/j.cub.2011.05.020  1
2011 Seitz H, Tushir JS, Zamore PD. A 5'-uridine amplifies miRNA/miRNA* asymmetry in Drosophila by promoting RNA-induced silencing complex formation. Silence. 2: 4. PMID 21649885 DOI: 10.1186/1758-907X-2-4  1
2011 Zamore PD, Ma S. Isolation of Drosophila melanogaster testes. Journal of Visualized Experiments : Jove. PMID 21610676 DOI: 10.3791/2641  1
2011 Broderick JA, Zamore PD. MicroRNA therapeutics. Gene Therapy. 18: 1104-10. PMID 21525952 DOI: 10.1038/gt.2011.50  1
2011 Cenik ES, Fukunaga R, Lu G, Dutcher R, Wang Y, Tanaka Hall TM, Zamore PD. Phosphate and R2D2 restrict the substrate specificity of Dicer-2, an ATP-driven ribonuclease. Molecular Cell. 42: 172-84. PMID 21419681 DOI: 10.1016/J.Molcel.2011.03.002  1
2011 Xie J, Xie Q, Zhang H, Ameres SL, Hung JH, Su Q, He R, Mu X, Seher Ahmed S, Park S, Kato H, Li C, Mueller C, Mello CC, Weng Z, ... ... Zamore PD, et al. MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 526-35. PMID 21179009 DOI: 10.1038/Mt.2010.279  1
2011 Berezikov E, Robine N, Samsonova A, Westholm JO, Naqvi A, Hung JH, Okamura K, Dai Q, Bortolamiol-Becet D, Martin R, Zhao Y, Zamore PD, Hannon GJ, Marra MA, Weng Z, et al. Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence. Genome Research. 21: 203-15. PMID 21177969 DOI: 10.1101/Gr.116657.110  1
2011 Ameres SL, Hung JH, Xu J, Weng Z, Zamore PD. Target RNA-directed tailing and trimming purifies the sorting of endo-siRNAs between the two Drosophila Argonaute proteins. Rna (New York, N.Y.). 17: 54-63. PMID 21106652 DOI: 10.1261/Rna.2498411  1
2010 Carone BR, Fauquier L, Habib N, Shea JM, Hart CE, Li R, Bock C, Li C, Gu H, Zamore PD, Meissner A, Weng Z, Hofmann HA, Friedman N, Rando OJ. Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals. Cell. 143: 1084-96. PMID 21183072 DOI: 10.1016/J.Cell.2010.12.008  1
2010 Zamore PD. Somatic piRNA biogenesis. The Embo Journal. 29: 3219-21. PMID 20924396 DOI: 10.1038/emboj.2010.232  1
2010 Ameres SL, Horwich MD, Hung JH, Xu J, Ghildiyal M, Weng Z, Zamore PD. Target RNA-directed trimming and tailing of small silencing RNAs. Science (New York, N.Y.). 328: 1534-9. PMID 20558712 DOI: 10.1126/Science.1187058  1
2010 Baulcombe DC, Zamore PD. Welcome to silence. Silence. 1: 1. PMID 20226068 DOI: 10.1186/1758-907X-1-1  1
2010 Ghildiyal M, Xu J, Seitz H, Weng Z, Zamore PD. Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway. Rna (New York, N.Y.). 16: 43-56. PMID 19917635 DOI: 10.1261/Rna.1972910  1
2009 Tushir JS, Zamore PD, Zhang Z. SnapShot: mouse piRNAs, PIWI proteins, and the ping-pong cycle. Cell. 139: 830-830.e1. PMID 19914174 DOI: 10.1016/j.cell.2009.10.042  1
2009 Tushir JS, Zamore PD, Zhang Z. SnapShot: Fly piRNAs, PIWI proteins, and the ping-pong cycle. Cell. 139: 634, 634.e1. PMID 19879848 DOI: 10.1016/j.cell.2009.10.021  1
2009 Pfister EL, Zamore PD. Huntington's disease: silencing a brutal killer. Experimental Neurology. 220: 226-9. PMID 19786020 DOI: 10.1016/j.expneurol.2009.09.017  1
2009 Klattenhoff C, Xi H, Li C, Lee S, Xu J, Khurana JS, Zhang F, Schultz N, Koppetsch BS, Nowosielska A, Seitz H, Zamore PD, Weng Z, Theurkauf WE. The Drosophila HP1 homolog Rhino is required for transposon silencing and piRNA production by dual-strand clusters. Cell. 138: 1137-49. PMID 19732946 DOI: 10.1016/J.Cell.2009.07.014  1
2009 Kadener S, Menet JS, Sugino K, Horwich MD, Weissbein U, Nawathean P, Vagin VV, Zamore PD, Nelson SB, Rosbash M. A role for microRNAs in the Drosophila circadian clock. Genes & Development. 23: 2179-91. PMID 19696147 DOI: 10.1101/Gad.1819509  1
2009 Izaurralde E, Zamore PD. Nucleus and gene expression. Current Opinion in Cell Biology. 21: 331-4. PMID 19447016 DOI: 10.1016/J.Ceb.2009.04.013  1
2009 Barringhaus KG, Zamore PD. MicroRNAs: regulating a change of heart. Circulation. 119: 2217-24. PMID 19398677 DOI: 10.1161/CIRCULATIONAHA.107.715839  1
2009 Li C, Vagin VV, Lee S, Xu J, Ma S, Xi H, Seitz H, Horwich MD, Syrzycka M, Honda BM, Kittler EL, Zapp ML, Klattenhoff C, Schulz N, Theurkauf WE, ... ... Zamore PD, et al. Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies. Cell. 137: 509-21. PMID 19395009 DOI: 10.1016/J.Cell.2009.04.027  1
2009 Pfister EL, Kennington L, Straubhaar J, Wagh S, Liu W, DiFiglia M, Landwehrmeyer B, Vonsattel JP, Zamore PD, Aronin N. Five siRNAs targeting three SNPs may provide therapy for three-quarters of Huntington's disease patients. Current Biology : Cb. 19: 774-8. PMID 19361997 DOI: 10.1016/J.Cub.2009.03.030  1
2009 Ghildiyal M, Zamore PD. Small silencing RNAs: an expanding universe. Nature Reviews. Genetics. 10: 94-108. PMID 19148191 DOI: 10.1038/nrg2504  1
2008 Liu W, Kennington LA, Rosas HD, Hersch S, Cha JH, Zamore PD, Aronin N. Linking SNPs to CAG repeat length in Huntington's disease patients. Nature Methods. 5: 951-3. PMID 18931668 DOI: 10.1038/Nmeth.1261  1
2008 Horwich MD, Zamore PD. Design and delivery of antisense oligonucleotides to block microRNA function in cultured Drosophila and human cells. Nature Protocols. 3: 1537-49. PMID 18802435 DOI: 10.1038/nprot.2008.145  1
2008 Rossi J, Zamore P, Kay MA. Wandering eye for RNAi. Nature Medicine. 14: 611. PMID 18535575 DOI: 10.1038/Nm0608-611  1
2008 Ghildiyal M, Seitz H, Horwich MD, Li C, Du T, Lee S, Xu J, Kittler EL, Zapp ML, Weng Z, Zamore PD. Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells. Science (New York, N.Y.). 320: 1077-81. PMID 18403677 DOI: 10.1126/Science.1157396  1
2008 Seitz H, Ghildiyal M, Zamore PD. Argonaute loading improves the 5' precision of both MicroRNAs and their miRNA* strands in flies. Current Biology : Cb. 18: 147-51. PMID 18207740 DOI: 10.1016/J.Cub.2007.12.049  1
2007 DiFiglia M, Sena-Esteves M, Chase K, Sapp E, Pfister E, Sass M, Yoder J, Reeves P, Pandey RK, Rajeev KG, Manoharan M, Sah DW, Zamore PD, Aronin N. Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits. Proceedings of the National Academy of Sciences of the United States of America. 104: 17204-9. PMID 17940007 DOI: 10.1073/Pnas.0708285104  1
2007 Matranga C, Zamore PD. Small silencing RNAs. Current Biology : Cb. 17: R789-93. PMID 17878043 DOI: 10.1016/j.cub.2007.07.014  1
2007 Du T, Zamore PD. Beginning to understand microRNA function. Cell Research. 17: 661-3. PMID 17694094 DOI: 10.1038/cr.2007.67  1
2007 Tomari Y, Du T, Zamore PD. Sorting of Drosophila small silencing RNAs. Cell. 130: 299-308. PMID 17662944 DOI: 10.1016/J.Cell.2007.05.057  1
2007 Förstemann K, Horwich MD, Wee L, Tomari Y, Zamore PD. Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1. Cell. 130: 287-97. PMID 17662943 DOI: 10.1016/J.Cell.2007.05.056  1
2007 Horwich MD, Li C, Matranga C, Vagin V, Farley G, Wang P, Zamore PD. The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC. Current Biology : Cb. 17: 1265-72. PMID 17604629 DOI: 10.1016/J.Cub.2007.06.030  1
2007 Zamore PD. RNA silencing: genomic defence with a slice of pi. Nature. 446: 864-5. PMID 17443172 DOI: 10.1038/446864a  1
2006 Sigova A, Vagin V, Zamore PD. Measuring the rates of transcriptional elongation in the female Drosophila melanogaster germ line by nuclear run-on. Cold Spring Harbor Symposia On Quantitative Biology. 71: 335-41. PMID 17381314 DOI: 10.1101/sqb.2006.71.031  1
2006 Zamore PD. RNA interference: big applause for silencing in Stockholm. Cell. 127: 1083-6. PMID 17174883 DOI: 10.1016/j.cell.2006.12.001  1
2006 Schwarz DS, Ding H, Kennington L, Moore JT, Schelter J, Burchard J, Linsley PS, Aronin N, Xu Z, Zamore PD. Designing siRNA that distinguish between genes that differ by a single nucleotide. Plos Genetics. 2: e140. PMID 16965178 DOI: 10.1371/journal.pgen.0020140  1
2006 Vagin VV, Sigova A, Li C, Seitz H, Gvozdev V, Zamore PD. A distinct small RNA pathway silences selfish genetic elements in the germline. Science (New York, N.Y.). 313: 320-4. PMID 16809489 DOI: 10.1126/Science.1129333  1
2006 Seitz H, Zamore PD. Rethinking the microprocessor. Cell. 125: 827-9. PMID 16751089 DOI: 10.1016/J.Cell.2006.05.018  1
2005 Matranga C, Tomari Y, Shin C, Bartel DP, Zamore PD. Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell. 123: 607-20. PMID 16271386 DOI: 10.1016/J.Cell.2005.08.044  1
2005 Du T, Zamore PD. microPrimer: the biogenesis and function of microRNA. Development (Cambridge, England). 132: 4645-52. PMID 16224044 DOI: 10.1242/dev.02070  1
2005 Zamore PD, Haley B. Ribo-gnome: the big world of small RNAs. Science (New York, N.Y.). 309: 1519-24. PMID 16141061 DOI: 10.1126/science.1111444  1
2005 Förstemann K, Tomari Y, Du T, Vagin VV, Denli AM, Bratu DP, Klattenhoff C, Theurkauf WE, Zamore PD. Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. Plos Biology. 3: e236. PMID 15918770 DOI: 10.1371/Journal.Pbio.0030236  1
2005 Tomari Y, Zamore PD. Perspective: machines for RNAi. Genes & Development. 19: 517-29. PMID 15741316 DOI: 10.1101/Gad.1284105  1
2005 Tomari Y, Zamore PD. MicroRNA biogenesis: drosha can't cut it without a partner. Current Biology : Cb. 15: R61-4. PMID 15668159 DOI: 10.1016/J.Cub.2004.12.057  1
2004 Matranga C, Zamore PD. Plant RNA interference in vitro. Cold Spring Harbor Symposia On Quantitative Biology. 69: 403-8. PMID 16117674 DOI: 10.1101/sqb.2004.69.403  1
2004 Tomari Y, Matranga C, Haley B, Martinez N, Zamore PD. A protein sensor for siRNA asymmetry. Science (New York, N.Y.). 306: 1377-80. PMID 15550672 DOI: 10.1126/Science.1102755  1
2004 Sigova A, Rhind N, Zamore PD. A single Argonaute protein mediates both transcriptional and posttranscriptional silencing in Schizosaccharomyces pombe. Genes & Development. 18: 2359-67. PMID 15371329 DOI: 10.1101/gad.1218004  1
2004 Mallory AC, Reinhart BJ, Jones-Rhoades MW, Tang G, Zamore PD, Barton MK, Bartel DP. MicroRNA control of PHABULOSA in leaf development: importance of pairing to the microRNA 5' region. The Embo Journal. 23: 3356-64. PMID 15282547 DOI: 10.1038/Sj.Emboj.7600340  1
2004 Haley B, Zamore PD. Kinetic analysis of the RNAi enzyme complex. Nature Structural & Molecular Biology. 11: 599-606. PMID 15170178 DOI: 10.1038/nsmb780  1
2004 Schwarz DS, Tomari Y, Zamore PD. The RNA-induced silencing complex is a Mg2+-dependent endonuclease. Current Biology : Cb. 14: 787-91. PMID 15120070 DOI: 10.1016/J.Cub.2004.03.008  1
2004 Tomari Y, Du T, Haley B, Schwarz DS, Bennett R, Cook HA, Koppetsch BS, Theurkauf WE, Zamore PD. RISC assembly defects in the Drosophila RNAi mutant armitage. Cell. 116: 831-41. PMID 15035985 DOI: 10.1016/S0092-8674(04)00218-1  1
2004 Zamore PD. Plant RNAi: How a viral silencing suppressor inactivates siRNA. Current Biology : Cb. 14: R198-200. PMID 15028237 DOI: 10.1016/j.cub.2004.02.021  1
2004 Hutvágner G, Simard MJ, Mello CC, Zamore PD. Sequence-specific inhibition of small RNA function. Plos Biology. 2: E98. PMID 15024405 DOI: 10.1371/journal.pbio.0020098  1
2004 Tang G, Zamore PD. Biochemical dissection of RNA silencing in plants. Methods in Molecular Biology (Clifton, N.J.). 257: 223-44. PMID 14770009 DOI: 10.1385/1-59259-750-5:223  1
2003 Schwarz DS, Hutvágner G, Du T, Xu Z, Aronin N, Zamore PD. Asymmetry in the assembly of the RNAi enzyme complex. Cell. 115: 199-208. PMID 14567917 DOI: 10.1016/S0092-8674(03)00759-1  1
2003 Ding H, Schwarz DS, Keene A, Affar el B, Fenton L, Xia X, Shi Y, Zamore PD, Xu Z. Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis. Aging Cell. 2: 209-17. PMID 12934714 DOI: 10.1046/J.1474-9728.2003.00054.X  1
2003 Haley B, Tang G, Zamore PD. In vitro analysis of RNA interference in Drosophila melanogaster. Methods (San Diego, Calif.). 30: 330-6. PMID 12828947 DOI: 10.1016/S1046-2023(03)00052-5  1
2003 Zamore PD, Aronin N. siRNAs knock down hepatitis. Nature Medicine. 9: 266-7. PMID 12612573 DOI: 10.1038/nm0303-266  1
2003 Tang G, Reinhart BJ, Bartel DP, Zamore PD. A biochemical framework for RNA silencing in plants. Genes & Development. 17: 49-63. PMID 12514099 DOI: 10.1101/Gad.1048103  1
2002 Schwarz DS, Hutvágner G, Haley B, Zamore PD. Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways. Molecular Cell. 10: 537-48. PMID 12408822 DOI: 10.1016/S1097-2765(02)00651-2  1
2002 Wang X, McLachlan J, Zamore PD, Hall TM. Modular recognition of RNA by a human pumilio-homology domain. Cell. 110: 501-12. PMID 12202039 DOI: 10.1016/S0092-8674(02)00873-5  1
2002 Hutvágner G, Zamore PD. A microRNA in a multiple-turnover RNAi enzyme complex. Science (New York, N.Y.). 297: 2056-60. PMID 12154197 DOI: 10.1126/science.1073827  1
2002 Zamore PD. Ancient pathways programmed by small RNAs. Science (New York, N.Y.). 296: 1265-9. PMID 12016303 DOI: 10.1126/science.1072457  1
2002 Schwarz DS, Zamore PD. Why do miRNAs live in the miRNP? Genes & Development. 16: 1025-31. PMID 12000786 DOI: 10.1101/gad.992502  1
2002 Feldbrügge M, Arizti P, Sullivan ML, Zamore PD, Belasco JG, Green PJ. Comparative analysis of the plant mRNA-destabilizing element, DST, in mammalian and tobacco cells. Plant Molecular Biology. 49: 215-23. PMID 11999376 DOI: 10.1023/A:1014936824187  1
2002 Hutvágner G, Zamore PD. RNAi: nature abhors a double-strand. Current Opinion in Genetics & Development. 12: 225-32. PMID 11893497 DOI: 10.1016/S0959-437X(02)00290-3  1
2002 Hutvágner G, Zamore PD. RNA interference: Horrified nature of double strands | ARNi: La nature a horreur des doubles brins Biofutur. 52-57.  1
2001 Zamore PD. Thirty-three years later, a glimpse at the ribonuclease III active site. Molecular Cell. 8: 1158-60. PMID 11885596 DOI: 10.1016/S1097-2765(01)00418-X  1
2001 Nykänen A, Haley B, Zamore PD. ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell. 107: 309-21. PMID 11701122 DOI: 10.1016/S0092-8674(01)00547-5  1
2001 Zamore PD. RNA interference: listening to the sound of silence. Nature Structural Biology. 8: 746-50. PMID 11524674 DOI: 10.1038/nsb0901-746  1
2001 Hutvágner G, McLachlan J, Pasquinelli AE, Bálint E, Tuschl T, Zamore PD. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science (New York, N.Y.). 293: 834-8. PMID 11452083 DOI: 10.1126/Science.1062961  1
2001 Wang X, Zamore PD, Hall TM. Crystal structure of a Pumilio homology domain. Molecular Cell. 7: 855-65. PMID 11336708 DOI: 10.1016/S1097-2765(01)00229-5  1
2000 Zamore PD, Tuschl T, Sharp PA, Bartel DP. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell. 101: 25-33. PMID 10778853 DOI: 10.1016/S0092-8674(00)80620-0  1
2000 Sharp PA, Zamore PD. Molecular biology. RNA interference. Science (New York, N.Y.). 287: 2431-3. PMID 10766620 DOI: 10.1126/science.287.5462.2431  1
1999 Tuschl T, Zamore PD, Lehmann R, Bartel DP, Sharp PA. Targeted mRNA degradation by double-stranded RNA in vitro. Genes & Development. 13: 3191-7. PMID 10617568 DOI: 10.1101/Gad.13.24.3191  1
1999 Zamore PD, Bartel DP, Lehmann R, Williamson JR. The PUMILIO-RNA interaction: a single RNA-binding domain monomer recognizes a bipartite target sequence. Biochemistry. 38: 596-604. PMID 9888799 DOI: 10.1021/Bi982264S  1
1997 Zamore PD, Williamson JR, Lehmann R. The Pumilio protein binds RNA through a conserved domain that defines a new class of RNA-binding proteins. Rna (New York, N.Y.). 3: 1421-33. PMID 9404893  1
1997 Curtis D, Treiber DK, Tao F, Zamore PD, Williamson JR, Lehmann R. A CCHC metal-binding domain in Nanos is essential for translational regulation. The Embo Journal. 16: 834-43. PMID 9049312 DOI: 10.1093/Emboj/16.4.834  1
1996 Zamore PD, Lehmann R. Drosophila development: homeodomains and translational control. Current Biology : Cb. 6: 773-5. PMID 8805294 DOI: 10.1016/S0960-9822(02)00591-2  1
1995 Curtis D, Lehmann R, Zamore PD. Translational regulation in development. Cell. 81: 171-8. PMID 7736569 DOI: 10.1016/0092-8674(95)90325-9  1
1993 Lee CG, Zamore PD, Green MR, Hurwitz J. RNA annealing activity is intrinsically associated with U2AF. The Journal of Biological Chemistry. 268: 13472-8. PMID 7685763  1
1993 Valcárcel J, Singh R, Zamore PD, Green MR. The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA. Nature. 362: 171-5. PMID 7680770 DOI: 10.1038/362171A0  0.92
1992 Zamore PD, Patton JG, Green MR. Cloning and domain structure of the mammalian splicing factor U2AF. Nature. 355: 609-14. PMID 1538748 DOI: 10.1038/355609A0  1
1992 Zhang M, Zamore PD, Carmo-Fonseca M, Lamond AI, Green MR. Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit. Proceedings of the National Academy of Sciences of the United States of America. 89: 8769-73. PMID 1388271 DOI: 10.1073/Pnas.89.18.8769  1
1991 Zamore PD, Green MR. Biochemical characterization of U2 snRNP auxiliary factor: an essential pre-mRNA splicing factor with a novel intranuclear distribution. The Embo Journal. 10: 207-14. PMID 1824937 DOI: 10.1002/J.1460-2075.1991.Tb07937.X  1
1991 Carmo-Fonseca M, Tollervey D, Pepperkok R, Barabino SM, Merdes A, Brunner C, Zamore PD, Green MR, Hurt E, Lamond AI. Mammalian nuclei contain foci which are highly enriched in components of the pre-mRNA splicing machinery. The Embo Journal. 10: 195-206. PMID 1824936 DOI: 10.1002/J.1460-2075.1991.Tb07936.X  1
1990 Zamore PD, Zapp ML, Green MR. Gene expression. RNA binding: beta s and basics. Nature. 348: 485-6. PMID 1701031 DOI: 10.1038/348485A0  1
1989 Zamore PD, Green MR. Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor. Proceedings of the National Academy of Sciences of the United States of America. 86: 9243-7. PMID 2531895 DOI: 10.1073/Pnas.86.23.9243  1
1988 Blacklow SC, Raines RT, Lim WA, Zamore PD, Knowles JR. Triosephosphate isomerase catalysis is diffusion controlled. Appendix: Analysis of triose phosphate equilibria in aqueous solution by 31P NMR. Biochemistry. 27: 1158-67. PMID 3365378 DOI: 10.1021/Bi00404A013  1
1988 Ruskin B, Zamore PD, Green MR. A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly. Cell. 52: 207-19. PMID 2963698 DOI: 10.1016/0092-8674(88)90509-0  1
1987 Ruskin B, Bindereif A, Nelson K, Pikielny C, Zamore P, Green MR. Biochemical mechanisms of mammalian pre-mRNA splicing Molecular Biology Reports. 12: 201. DOI: 10.1007/Bf00356900  1
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