| Year |
Citation |
Score |
| 2023 |
Albarnaz JD, Kite J, Oliveira M, Li H, Di Y, Christensen MH, Paulo JA, Antrobus R, Gygi SP, Schmidt FI, Huttlin EL, Smith GL, Weekes MP. Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection. Nature Communications. 14: 8134. PMID 38065956 DOI: 10.1038/s41467-023-43299-8 |
0.422 |
|
| 2023 |
Bohmer MJ, Wang J, Istvan ES, Luth MR, Collins JE, Huttlin EL, Wang L, Mittal N, Hao M, Kwiatkowski NP, Gygi SP, Chakrabarti R, Deng X, Goldberg DE, Winzeler EA, et al. Human Polo-like Kinase Inhibitors as Antiplasmodials. Acs Infectious Diseases. PMID 36919909 DOI: 10.1021/acsinfecdis.3c00025 |
0.383 |
|
| 2023 |
Yu Q, Liu X, Keller MP, Navarrete-Perea J, Zhang T, Fu S, Vaites LP, Shuken SR, Schmid E, Keele GR, Li J, Huttlin EL, Rashan EH, Simcox J, Churchill GA, et al. Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression. Nature Communications. 14: 555. PMID 36732331 DOI: 10.1038/s41467-023-36269-7 |
0.734 |
|
| 2023 |
Mitchell DC, Kuljanin M, Li J, Van Vranken JG, Bulloch N, Schweppe DK, Huttlin EL, Gygi SP. A proteome-wide atlas of drug mechanism of action. Nature Biotechnology. PMID 36593396 DOI: 10.1038/s41587-022-01539-0 |
0.698 |
|
| 2022 |
Xiao H, Bozi LHM, Sun Y, Riley CL, Philip VM, Chen M, Li J, Zhang T, Mills EL, Emont MP, Sun W, Reddy A, Garrity R, Long J, Becher T, ... ... Huttlin EL, et al. Architecture of the outbred brown fat proteome defines regulators of metabolic physiology. Cell. PMID 36334589 DOI: 10.1016/j.cell.2022.10.003 |
0.464 |
|
| 2022 |
Gassaway BM, Li J, Rad R, Mintseris J, Mohler K, Levy T, Aguiar M, Beausoleil SA, Paulo JA, Rinehart J, Huttlin EL, Gygi SP. A multi-purpose, regenerable, proteome-scale, human phosphoserine resource for phosphoproteomics. Nature Methods. PMID 36280721 DOI: 10.1038/s41592-022-01638-5 |
0.779 |
|
| 2022 |
Chick JM, Munger SC, Simecek P, Huttlin EL, Choi K, Gatti DM, Raghupathy N, Svenson KL, Churchill GA, Gygi SP. Author Correction: Defining the consequences of genetic variation on a proteome-wide scale. Nature. 606: E16. PMID 35672473 DOI: 10.1038/s41586-022-04920-w |
0.354 |
|
| 2021 |
Qin Y, Huttlin EL, Winsnes CF, Gosztyla ML, Wacheul L, Kelly MR, Blue SM, Zheng F, Chen M, Schaffer LV, Licon K, Bäckström A, Vaites LP, Lee JJ, Ouyang W, et al. A multi-scale map of cell structure fusing protein images and interactions. Nature. PMID 34819669 DOI: 10.1038/s41586-021-04115-9 |
0.427 |
|
| 2021 |
Li J, Cai Z, Vaites LP, Shen N, Mitchell DC, Huttlin EL, Paulo JA, Harry BL, Gygi SP. Proteome-wide mapping of short-lived proteins in human cells. Molecular Cell. PMID 34626566 DOI: 10.1016/j.molcel.2021.09.015 |
0.473 |
|
| 2021 |
Huttlin EL, Bruckner RJ, Navarrete-Perea J, Cannon JR, Baltier K, Gebreab F, Gygi MP, Thornock A, Zarraga G, Tam S, Szpyt J, Gassaway BM, Panov A, Parzen H, Fu S, et al. Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. Cell. PMID 33961781 DOI: 10.1016/j.cell.2021.04.011 |
0.785 |
|
| 2020 |
Li J, Van Vranken JG, Paulo JA, Huttlin EL, Gygi SP. Selection of Heating Temperatures Improves the Sensitivity of Proteome Integral Solubility Alteration (PISA) Assay. Journal of Proteome Research. PMID 32243163 DOI: 10.1021/Acs.Jproteome.0C00063 |
0.478 |
|
| 2020 |
Li J, Van Vranken JG, Pontano Vaites L, Schweppe DK, Huttlin EL, Etienne C, Nandhikonda P, Viner R, Robitaille AM, Thompson AH, Kuhn K, Pike I, Bomgarden RD, Rogers JC, Gygi SP, et al. TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples. Nature Methods. PMID 32203386 DOI: 10.1038/S41592-020-0781-4 |
0.755 |
|
| 2020 |
Schweppe DK, Eng JK, Yu Q, Bailey D, Rad R, Navarrete-Perea J, Huttlin EL, Erickson BK, Paulo JA, Gygi SP. Full-featured, real-time database searching platform enables fast and accurate multiplexed quantitative proteomics. Journal of Proteome Research. PMID 32126768 DOI: 10.1021/Acs.Jproteome.9B00860 |
0.732 |
|
| 2020 |
Xiao H, Jedrychowski MP, Schweppe DK, Huttlin EL, Yu Q, Heppner DE, Li J, Long J, Mills EL, Szpyt J, He Z, Du G, Garrity R, Reddy A, Vaites LP, et al. A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging. Cell. PMID 32109415 DOI: 10.1016/J.Cell.2020.02.012 |
0.725 |
|
| 2019 |
Nobre LV, Nightingale K, Ravenhill BJ, Antrobus R, Soday L, Nichols J, Davies JA, Seirafian S, Wang EC, Davison AJ, Wilkinson GW, Stanton RJ, Huttlin EL, Weekes MP. Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions. Elife. 8. PMID 31873071 DOI: 10.7554/Elife.49894 |
0.385 |
|
| 2019 |
Li J, Paulo JA, Nusinow DP, Huttlin EL, Gygi SP. Investigation of Proteomic and Phosphoproteomic Responses to Signaling Network Perturbations Reveals Functional Pathway Organizations in Yeast. Cell Reports. 29: 2092-2104.e4. PMID 31722220 DOI: 10.1016/J.Celrep.2019.10.034 |
0.795 |
|
| 2019 |
Nobre LV, Nightingale K, Ravenhill BJ, Antrobus R, Soday L, Nichols J, Davies JA, Seirafian S, Wang EC, Davison AJ, Wilkinson GW, Stanton RJ, Huttlin EL, Weekes MP. Author response: Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions Elife. DOI: 10.7554/Elife.49894.Sa2 |
0.326 |
|
| 2018 |
Nightingale K, Lin KM, Ravenhill BJ, Davies C, Nobre L, Fielding CA, Ruckova E, Fletcher-Etherington A, Soday L, Nichols H, Sugrue D, Wang ECY, Moreno P, Umrania Y, Huttlin EL, et al. High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms. Cell Host & Microbe. PMID 30122656 DOI: 10.1016/J.Chom.2018.07.011 |
0.366 |
|
| 2018 |
Pease BN, Huttlin EL, Jedrychowski MP, Dorin-Semblat D, Sebastiani D, Segarra DT, Roberts BF, Chakrabarti R, Doerig C, Gygi SP, Chakrabarti D. Characterization of Plasmodium falciparum Atypical Kinase PfPK7-Dependent Phosphoproteome. Journal of Proteome Research. PMID 29678115 DOI: 10.1021/Acs.Jproteome.8B00062 |
0.527 |
|
| 2017 |
O'Brien JJ, O'Connell JD, Paulo JA, Thakurta S, Rose CM, Weekes MP, Huttlin EL, Gygi SP. Compositional Proteomics: Effects of Spatial Constraints on Protein Quantification Utilizing Isobaric Tags. Journal of Proteome Research. PMID 29195270 DOI: 10.1021/Acs.Jproteome.7B00699 |
0.562 |
|
| 2017 |
Schweppe DK, Huttlin EL, Harper JW, Gygi SP. BioPlex Display: An interactive suite for large-scale, AP-MS protein-protein interaction data. Journal of Proteome Research. PMID 29054129 DOI: 10.1021/Acs.Jproteome.7B00572 |
0.744 |
|
| 2017 |
Pontano Vaites L, Paulo JA, Huttlin EL, Harper JW. Systematic analysis of human cells lacking ATG8 proteins uncovers roles for GABARAPs and the CCZ1/MON1 regulator C18orf8/RMC1 in macro and selective autophagic flux. Molecular and Cellular Biology. PMID 29038162 DOI: 10.1128/Mcb.00392-17 |
0.382 |
|
| 2017 |
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, et al. Architecture of the human interactome defines protein communities and disease networks. Nature. PMID 28514442 DOI: 10.1038/Nature22366 |
0.757 |
|
| 2016 |
Everley RA, Huttlin EL, Erickson AR, Beausoleil SA, Gygi SP. Neutral Loss is a Very Common Occurrence in Phosphotyrosine-containing Peptides Labeled with Isobaric Tags. Journal of Proteome Research. PMID 27978624 DOI: 10.1021/Acs.Jproteome.6B00487 |
0.731 |
|
| 2016 |
Chick JM, Munger SC, Simecek P, Huttlin EL, Choi K, Gatti DM, Raghupathy N, Svenson KL, Churchill GA, Gygi SP. Defining the consequences of genetic variation on a proteome-wide scale. Nature. PMID 27309819 DOI: 10.1038/Nature18270 |
0.538 |
|
| 2015 |
Raman M, Sergeev M, Garnaas M, Lydeard JR, Huttlin EL, Goessling W, Shah JV, Harper JW. Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis. Nature Cell Biology. PMID 26389662 DOI: 10.1038/Ncb3238 |
0.399 |
|
| 2015 |
Chick JM, Kolippakkam D, Nusinow DP, Zhai B, Rad R, Huttlin EL, Gygi SP. Erratum: A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified peptides. Nature Biotechnology. 33: 882. PMID 26252148 DOI: 10.1038/nbt0815-882d |
0.777 |
|
| 2015 |
Huttlin EL, Ting L, Bruckner RJ, Gebreab F, Gygi MP, Szpyt J, Tam S, Zarraga G, Colby G, Baltier K, Dong R, Guarani V, Vaites LP, Ordureau A, Rad R, et al. The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 162: 425-40. PMID 26186194 DOI: 10.1016/J.Cell.2015.06.043 |
0.791 |
|
| 2015 |
Chick JM, Kolippakkam D, Nusinow DP, Zhai B, Rad R, Huttlin EL, Gygi SP. A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified peptides. Nature Biotechnology. 33: 743-9. PMID 26076430 DOI: 10.1038/Nbt.3267 |
0.784 |
|
| 2015 |
Elia AE, Boardman AP, Wang DC, Huttlin EL, Everley RA, Dephoure N, Zhou C, Koren I, Gygi SP, Elledge SJ. Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response. Molecular Cell. PMID 26051181 DOI: 10.1016/J.Molcel.2015.05.006 |
0.463 |
|
| 2015 |
Guarani V, McNeill EM, Paulo JA, Huttlin EL, Fröhlich F, Gygi SP, Van Vactor D, Harper JW. QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology. Elife. 4. PMID 25997101 DOI: 10.7554/Elife.06265 |
0.459 |
|
| 2015 |
Guarani V, McNeill EM, Paulo JA, Huttlin EL, Fröhlich F, Gygi SP, Vactor DV, Harper JW. Author response: QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology Elife. DOI: 10.7554/Elife.06265.015 |
0.449 |
|
| 2015 |
Huttlin EL, Ting L, Bruckner RJ, Gebreab F, Gygi MP, Szpyt J, Tam S, Zarraga G, Colby G, Baltier K, Dong R, Guarani V, Vaites LP, Ordureau A, Rad R, et al. The BioPlex Network: A Systematic Exploration of the Human Interactome Cell. 162: 425-440. DOI: 10.1016/j.cell.2015.06.043 |
0.752 |
|
| 2014 |
McAlister GC, Nusinow DP, Jedrychowski MP, Wühr M, Huttlin EL, Erickson BK, Rad R, Haas W, Gygi SP. MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes. Analytical Chemistry. 86: 7150-8. PMID 24927332 DOI: 10.1021/Ac502040V |
0.763 |
|
| 2014 |
Weekes MP, Tomasec P, Huttlin EL, Fielding CA, Nusinow D, Stanton RJ, Wang EC, Aicheler R, Murrell I, Wilkinson GW, Lehner PJ, Gygi SP. Quantitative temporal viromics: an approach to investigate host-pathogen interaction. Cell. 157: 1460-72. PMID 24906157 DOI: 10.1016/J.Cell.2014.04.028 |
0.783 |
|
| 2014 |
Tcherkezian J, Cargnello M, Romeo Y, Huttlin EL, Lavoie G, Gygi SP, Roux PP. Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation. Genes & Development. 28: 357-71. PMID 24532714 DOI: 10.1101/Gad.231407.113 |
0.497 |
|
| 2014 |
Guarani V, Paulo J, Zhai B, Huttlin EL, Gygi SP, Harper JW. TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial complex I assembly factor through association with the MCIA complex. Molecular and Cellular Biology. 34: 847-61. PMID 24344204 DOI: 10.1128/Mcb.01551-13 |
0.438 |
|
| 2013 |
Ivancic MM, Huttlin EL, Chen X, Pleiman JK, Irving AA, Hegeman AD, Dove WF, Sussman MR. Candidate serum biomarkers for early intestinal cancer using 15N metabolic labeling and quantitative proteomics in the ApcMin/+ mouse. Journal of Proteome Research. 12: 4152-66. PMID 23924158 DOI: 10.1021/Pr400467C |
0.724 |
|
| 2013 |
Pease BN, Huttlin EL, Jedrychowski MP, Talevich E, Harmon J, Dillman T, Kannan N, Doerig C, Chakrabarti R, Gygi SP, Chakrabarti D. Global analysis of protein expression and phosphorylation of three stages of Plasmodium falciparum intraerythrocytic development. Journal of Proteome Research. 12: 4028-45. PMID 23914800 DOI: 10.1021/Pr400394G |
0.521 |
|
| 2013 |
McAllister FE, Niepel M, Haas W, Huttlin E, Sorger PK, Gygi SP. Mass spectrometry based method to increase throughput for kinome analyses using ATP probes. Analytical Chemistry. 85: 4666-74. PMID 23607489 DOI: 10.1021/Ac303478G |
0.498 |
|
| 2013 |
Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Nature. 496: 372-6. PMID 23503661 DOI: 10.1038/Nature12043 |
0.482 |
|
| 2013 |
Zhang X, Lavoie G, Fort L, Huttlin EL, Tcherkezian J, Galan JA, Gu H, Gygi SP, Carreno S, Roux PP. Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility. Molecular and Cellular Biology. 33: 1657-70. PMID 23401857 DOI: 10.1128/Mcb.01353-12 |
0.495 |
|
| 2013 |
Zhang X, Lavoie G, Fort L, Huttlin EL, Tcherkezian J, Galan JA, Gu H, Gygi SP, Carreno S, Roux PP. Abstract 5191: Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility. Cancer Research. 73: 5191-5191. DOI: 10.1158/1538-7445.Am2013-5191 |
0.486 |
|
| 2012 |
Cargnello M, Tcherkezian J, Dorn JF, Huttlin EL, Maddox PS, Gygi SP, Roux PP. Phosphorylation of the eukaryotic translation initiation factor 4E-transporter (4E-T) by c-Jun N-terminal kinase promotes stress-dependent P-body assembly. Molecular and Cellular Biology. 32: 4572-84. PMID 22966201 DOI: 10.1128/Mcb.00544-12 |
0.442 |
|
| 2012 |
McAlister GC, Huttlin EL, Haas W, Ting L, Jedrychowski MP, Rogers JC, Kuhn K, Pike I, Grothe RA, Blethrow JD, Gygi SP. Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses. Analytical Chemistry. 84: 7469-78. PMID 22880955 DOI: 10.1021/Ac301572T |
0.469 |
|
| 2012 |
Gygi SP, Huttlin EL, Wu R, Haas W, Dephoure N, Sowa M, Zhai B. Reply to Phosphorylation sites of higher stoichiometry are more conserved Nature Methods. 9: 318. DOI: 10.1038/Nmeth.1942 |
0.434 |
|
| 2011 |
Jedrychowski MP, Huttlin EL, Haas W, Sowa ME, Rad R, Gygi SP. Evaluation of HCD- and CID-type fragmentation within their respective detection platforms for murine phosphoproteomics. Molecular & Cellular Proteomics : McP. 10: M111.009910. PMID 21917720 DOI: 10.1074/Mcp.M111.009910 |
0.529 |
|
| 2011 |
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Systematic and quantitative assessment of the ubiquitin-modified proteome. Molecular Cell. 44: 325-40. PMID 21906983 DOI: 10.1016/J.Molcel.2011.08.025 |
0.534 |
|
| 2011 |
Wu R, Haas W, Dephoure N, Huttlin EL, Zhai B, Sowa ME, Gygi SP. A large-scale method to measure absolute protein phosphorylation stoichiometries. Nature Methods. 8: 677-83. PMID 21725298 DOI: 10.1038/Nmeth.1636 |
0.704 |
|
| 2011 |
Wu R, Dephoure N, Haas W, Huttlin EL, Zhai B, Sowa ME, Gygi SP. Correct interpretation of comprehensive phosphorylation dynamics requires normalization by protein expression changes. Molecular & Cellular Proteomics : McP. 10: M111.009654. PMID 21551504 DOI: 10.1074/Mcp.M111.009654 |
0.722 |
|
| 2010 |
Huttlin EL, Jedrychowski MP, Elias JE, Goswami T, Rad R, Beausoleil SA, Villén J, Haas W, Sowa ME, Gygi SP. A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 143: 1174-89. PMID 21183079 DOI: 10.1016/J.Cell.2010.12.001 |
0.797 |
|
| 2009 |
Huttlin EL, Chen X, Barrett-Wilt GA, Hegeman AD, Halberg RB, Harms AC, Newton MA, Dove WF, Sussman MR. Discovery and validation of colonic tumor-associated proteins via metabolic labeling and stable isotopic dilution. Proceedings of the National Academy of Sciences of the United States of America. 106: 17235-40. PMID 19805096 DOI: 10.1073/Pnas.0909282106 |
0.74 |
|
| 2009 |
Sussman MR, Huttlin EL, Wohlbach DJ. Democratization and integration of genomic profiling tools. Methods in Molecular Biology (Clifton, N.J.). 553: 373-93. PMID 19588117 DOI: 10.1007/978-1-60327-563-7_20 |
0.757 |
|
| 2008 |
McIlwain S, Page D, Huttlin EL, Sussman MR. Matching isotopic distributions from metabolically labeled samples. Bioinformatics (Oxford, England). 24: i339-47. PMID 18586733 DOI: 10.1093/bioinformatics/btn190 |
0.524 |
|
| 2008 |
Mock T, Samanta MP, Iverson V, Berthiaume C, Robison M, Holtermann K, Durkin C, Bondurant SS, Richmond K, Rodesch M, Kallas T, Huttlin EL, Cerrina F, Sussman MR, Armbrust EV. Whole-genome expression profiling of the marine diatom Thalassiosira pseudonana identifies genes involved in silicon bioprocesses. Proceedings of the National Academy of Sciences of the United States of America. 105: 1579-84. PMID 18212125 DOI: 10.1073/Pnas.0707946105 |
0.729 |
|
| 2008 |
Huttlin EL, Hegeman AD, Sussman MR. Chapter 20 Metabolic Labeling Approaches for the Relative Quantification of Proteins Comprehensive Analytical Chemistry. 52: 479-513,529-530. DOI: 10.1016/S0166-526X(08)00220-1 |
0.719 |
|
| 2007 |
Hegeman AD, Schulte CF, Cui Q, Lewis IA, Huttlin EL, Eghbalnia H, Harms AC, Ulrich EL, Markley JL, Sussman MR. Stable isotope assisted assignment of elemental compositions for metabolomics. Analytical Chemistry. 79: 6912-21. PMID 17708672 DOI: 10.1021/Ac070346T |
0.707 |
|
| 2007 |
McIlwain S, Page D, Huttlin EL, Sussman MR. Using dynamic programming to create isotopic distribution maps from mass spectra. Bioinformatics (Oxford, England). 23: i328-36. PMID 17646314 DOI: 10.1093/bioinformatics/btm198 |
0.487 |
|
| 2007 |
Nelson CJ, Huttlin EL, Hegeman AD, Harms AC, Sussman MR. Implications of 15N-metabolic labeling for automated peptide identification in Arabidopsis thaliana. Proteomics. 7: 1279-92. PMID 17443642 DOI: 10.1002/Pmic.200600832 |
0.776 |
|
| 2007 |
Huttlin EL, Hegeman AD, Harms AC, Sussman MR. Comparison of full versus partial metabolic labeling for quantitative proteomics analysis in Arabidopsis thaliana. Molecular & Cellular Proteomics : McP. 6: 860-81. PMID 17293592 DOI: 10.1074/Mcp.M600347-Mcp200 |
0.732 |
|
| 2007 |
Huttlin EL, Hegeman AD, Harms AC, Sussman MR. Prediction of error associated with false-positive rate determination for peptide identification in large-scale proteomics experiments using a combined reverse and forward peptide sequence database strategy. Journal of Proteome Research. 6: 392-8. PMID 17203984 DOI: 10.1021/Pr0603194 |
0.72 |
|
| 2006 |
Pischke MS, Huttlin EL, Hegeman AD, Sussman MR. A transcriptome-based characterization of habituation in plant tissue culture. Plant Physiology. 140: 1255-78. PMID 16489130 DOI: 10.1104/Pp.105.076059 |
0.734 |
|
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