| Year |
Citation |
Score |
| 2023 |
Hartung HP, Cree BAC, Barnett M, Meuth SG, Bar-Or A, Steinman L. Bioavailable central nervous system disease-modifying therapies for multiple sclerosis. Frontiers in Immunology. 14: 1290666. PMID 38162670 DOI: 10.3389/fimmu.2023.1290666 |
0.301 |
|
| 2023 |
Hashemi E, Srivastava IN, Aguirre A, Yoseph ET, Kaushal E, Awani A, Ryu JK, Akassoglou K, Talebian S, Chu P, Pisani L, Musolino P, Steinman L, Doyle K, Robinson WH, et al. A novel mouse model of cerebral adrenoleukodystrophy highlights NLRP3 activity in lesion pathogenesis. Biorxiv : the Preprint Server For Biology. PMID 37986739 DOI: 10.1101/2023.11.07.564025 |
0.612 |
|
| 2023 |
Mader MM, Napole A, Wu D, Shibuya Y, Scavetti A, Foltz A, Atkins M, Hahn O, Yoo Y, Danziger R, Tan C, Wyss-Coray T, Steinman L, Wernig M. Augmentation of a neuroprotective myeloid state by hematopoietic cell transplantation. Biorxiv : the Preprint Server For Biology. PMID 36945385 DOI: 10.1101/2023.03.10.532123 |
0.338 |
|
| 2022 |
Chen BY, Salas JR, Trias AO, Perez Rodriguez A, Tsang JE, Guemes M, Le TM, Galic Z, Shepard HM, Steinman L, Nathanson DA, Czernin J, Witte ON, Radu CG, Schultz KA, et al. Targeting deoxycytidine kinase improves symptoms in mouse models of multiple sclerosis. Immunology. PMID 35986643 DOI: 10.1111/imm.13569 |
0.339 |
|
| 2020 |
Kuerten S, Lanz TV, Lingampalli N, Lahey LJ, Kleinschnitz C, Mäurer M, Schroeter M, Braune S, Ziemssen T, Ho PP, Robinson WH, Steinman L. Autoantibodies against central nervous system antigens in a subset of B cell-dominant multiple sclerosis patients. Proceedings of the National Academy of Sciences of the United States of America. PMID 32817492 DOI: 10.1073/Pnas.2011249117 |
0.421 |
|
| 2020 |
Steinman L. A sugar-coated strategy to treat a rare neurologic disease provides a blueprint for a decoy glycan therapeutic and a potential vaccine for CoViD-19: An Editorial Highlight for "Selective inhibition of anti-MAG IgM autoantibody binding to myelin by an antigen specific glycopolymer"on https://doi.org/10.1111/jnc.15021. Journal of Neurochemistry. PMID 32574379 DOI: 10.1111/Jnc.15098 |
0.337 |
|
| 2020 |
Frohman EM, Villemarette-Pittman NR, Melamed E, Cruz RA, Longmuir R, Varkey TC, Steinman L, Zamvil SS, Frohman TC. Part I. SARS-CoV-2 triggered 'PANIC' attack in severe COVID-19. Journal of the Neurological Sciences. 116936. PMID 32532449 DOI: 10.1016/J.Jns.2020.116936 |
0.318 |
|
| 2020 |
Villoslada P, Steinman L. New targets and therapeutics for neuroprotection, remyelination and repair in multiple sclerosis. Expert Opinion On Investigational Drugs. 1-17. PMID 32299268 DOI: 10.1080/13543784.2020.1757647 |
0.352 |
|
| 2019 |
Bar-Or A, Pender MP, Khanna R, Steinman L, Hartung HP, Maniar T, Croze E, Aftab BT, Giovannoni G, Joshi MJ. Epstein-Barr Virus in Multiple Sclerosis: Theory and Emerging Immunotherapies. Trends in Molecular Medicine. PMID 31862243 DOI: 10.1016/J.Molmed.2019.11.003 |
0.386 |
|
| 2019 |
Steinman L, Ho PP, Robinson WH, Utz PJ, Villoslada P. Antigen-specific tolerance to self-antigens in protein replacement therapy, gene therapy and autoimmunity. Current Opinion in Immunology. 61: 46-53. PMID 31476445 DOI: 10.1016/J.Coi.2019.07.011 |
0.337 |
|
| 2019 |
Costanza M, Poliani PL, Portararo P, Cappetti B, Musio S, Pagani F, Steinman L, Colombo MP, Pedotti R, Sangaletti S. DNA threads released by activated CD4 T lymphocytes provide autocrine costimulation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30988194 DOI: 10.1073/Pnas.1822013116 |
0.391 |
|
| 2019 |
Zubizarreta I, Flórez-Grau G, Vila G, Cabezón R, España C, Andorra M, Saiz A, Llufriu S, Sepulveda M, Sola-Valls N, Martinez-Lapiscina EH, Pulido-Valdeolivas I, Casanova B, Martinez Gines M, Tellez N, ... ... Steinman L, et al. Immune tolerance in multiple sclerosis and neuromyelitis optica with peptide-loaded tolerogenic dendritic cells in a phase 1b trial. Proceedings of the National Academy of Sciences of the United States of America. PMID 30962374 DOI: 10.1073/Pnas.1820039116 |
0.406 |
|
| 2019 |
Villoslada P, Vila G, Colafrancesco V, Moreno B, Fernandez-Diez B, Vazquez R, Pertsovskaya I, Zubizarreta I, Pulido-Valdeolivas I, Messeguer J, Vendrell-Navarro G, Frade JM, López-Sánchez N, Teixido M, Giralt E, ... ... Steinman L, et al. Axonal and Myelin Neuroprotection by the Peptoid BN201 in Brain Inflammation. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 30815844 DOI: 10.1007/S13311-019-00717-4 |
0.319 |
|
| 2018 |
Rothbard JB, Kurnellas MP, Ousman SS, Brownell S, Rothbard JJ, Steinman L. Small Heat Shock Proteins, Amyloid Fibrils, and Nicotine Stimulate a Common Immune Suppressive Pathway with Implications for Future Therapies. Cold Spring Harbor Perspectives in Medicine. PMID 30249602 DOI: 10.1101/Cshperspect.A034223 |
0.394 |
|
| 2018 |
Rothbard JB, Rothbard JJ, Soares L, Fathman CG, Steinman L. Identification of a common immune regulatory pathway induced by small heat shock proteins, amyloid fibrils, and nicotine. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915045 DOI: 10.1073/Pnas.1804599115 |
0.309 |
|
| 2018 |
Moreno MA, Or-Geva N, Aftab BT, Khanna R, Croze E, Steinman L, Han MH. Molecular signature of Epstein-Barr virus infection in MS brain lesions. Neurology(R) Neuroimmunology & Neuroinflammation. 5: e466. PMID 29892607 DOI: 10.1212/Nxi.0000000000000466 |
0.649 |
|
| 2018 |
Kaneko K, Sato DK, Nakashima I, Ogawa R, Akaishi T, Takai Y, Nishiyama S, Takahashi T, Misu T, Kuroda H, Tanaka S, Nomura K, Hashimoto Y, Callegaro D, Steinman L, et al. CSF cytokine profile in MOG-IgG+ neurological disease is similar to AQP4-IgG+ NMOSD but distinct from MS: a cross-sectional study and potential therapeutic implications. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 29875186 DOI: 10.1136/Jnnp-2018-317969 |
0.365 |
|
| 2018 |
Ajami B, Samusik N, Wieghofer P, Ho PP, Crotti A, Bjornson Z, Prinz M, Fantl WJ, Nolan GP, Steinman L. Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models. Nature Neuroscience. PMID 29507414 DOI: 10.1038/S41593-018-0100-X |
0.346 |
|
| 2018 |
Ajami B, Steinman L. Nonclassical monocytes: are they the next therapeutic targets in multiple sclerosis? Immunology and Cell Biology. PMID 29352485 DOI: 10.1111/Imcb.12004 |
0.334 |
|
| 2017 |
Bruinsma IB, van Dijk M, Bridel C, van de Lisdonk T, Haverkort SQ, Runia TF, Steinman L, Hintzen RQ, Killestein J, Verbeek MM, Teunissen CE, de Jong BA. Regulator of oligodendrocyte maturation, miR-219, a potential biomarker for MS. Journal of Neuroinflammation. 14: 235. PMID 29202778 DOI: 10.1186/S12974-017-1006-3 |
0.351 |
|
| 2017 |
Bhat R, Mahapatra S, Axtell RC, Steinman L. Amelioration of ongoing experimental autoimmune encephalomyelitis with fluoxetine. Journal of Neuroimmunology. 313: 77-81. PMID 29153612 DOI: 10.1016/J.Jneuroim.2017.10.012 |
0.454 |
|
| 2017 |
DeFalco J, Harbell M, Manning-Bog A, Baia G, Scholz A, Millare B, Sumi M, Zhang D, Chu F, Dowd C, Zuno-Mitchell P, Kim D, Leung Y, Jiang S, Tang X, ... ... Steinman L, et al. Non-progressing cancer patients have persistent B cell responses expressing shared antibody paratopes that target public tumor antigens. Clinical Immunology (Orlando, Fla.). PMID 29031828 DOI: 10.1016/J.Clim.2017.10.002 |
0.309 |
|
| 2017 |
Sagan SA, Cruz-Herranz A, Spencer CM, Ho PP, Steinman L, Green AJ, Sobel RA, Zamvil SS. Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4. Journal of Visualized Experiments : Jove. PMID 28872108 DOI: 10.3791/56185 |
0.411 |
|
| 2017 |
Lepka K, Volbracht K, Bill E, Schneider R, Rios N, Hildebrandt T, Ingwersen J, Prozorovski T, Lillig CH, van Horssen J, Steinman L, Hartung HP, Radi R, Holmgren A, Aktas O, et al. Iron-sulfur glutaredoxin 2 protects oligodendrocytes against damage induced by nitric oxide release from activated microglia. Glia. PMID 28618115 DOI: 10.1002/Glia.23178 |
0.335 |
|
| 2017 |
Musio S, Costanza M, Poliani PL, Fontana E, Cominelli M, Abolafio G, Steinman L, Pedotti R. Treatment with anti-FcεRIα antibody exacerbates EAE and T-cell immunity against myelin. Neurology(R) Neuroimmunology & Neuroinflammation. 4: e342. PMID 28616446 DOI: 10.1212/Nxi.0000000000000342 |
0.453 |
|
| 2017 |
Steinman L. Induction of New Autoimmune Diseases After Alemtuzumab Therapy for Multiple Sclerosis: Learning from Adversity. Jama Neurology. PMID 28604941 DOI: 10.1001/Jamaneurol.2017.0325 |
0.325 |
|
| 2017 |
Berkovich R, Bakshi R, Amezcua L, Axtell RC, Cen SY, Tauhid S, Neema M, Steinman L. Adrenocorticotropic hormone versus methylprednisolone added to interferon β in patients with multiple sclerosis experiencing breakthrough disease: a randomized, rater-blinded trial. Therapeutic Advances in Neurological Disorders. 10: 3-17. PMID 28450891 DOI: 10.1177/1756285616670060 |
0.31 |
|
| 2017 |
Hohlfeld R, Steinman L. T Cell-Transfer Experimental Autoimmune Encephalomyelitis: Pillar of Multiple Sclerosis and Autoimmunity. Journal of Immunology (Baltimore, Md. : 1950). 198: 3381-3383. PMID 28416715 DOI: 10.4049/Jimmunol.1700346 |
0.41 |
|
| 2017 |
Endriz J, Ho PP, Steinman L. Time correlation between mononucleosis and initial symptoms of MS. Neurology(R) Neuroimmunology & Neuroinflammation. 4: e308. PMID 28271078 DOI: 10.1212/Nxi.0000000000000308 |
0.305 |
|
| 2017 |
Kuipers HF, Yoon J, van Horssen J, Han MH, Bollyky PL, Palmer TD, Steinman L. Phosphorylation of αB-crystallin supports reactive astrogliosis in demyelination. Proceedings of the National Academy of Sciences of the United States of America. PMID 28196893 DOI: 10.1073/Pnas.1621314114 |
0.677 |
|
| 2017 |
Elfeky M, Kamimura D, Arima Y, Murakami M, Steinman L. Targeting molecules involved in immune cell trafficking to the central nervous system for therapy in multiple sclerosis Clinical and Experimental Neuroimmunology. 8: 183-191. DOI: 10.1111/Cen3.12399 |
0.429 |
|
| 2016 |
Sagan SA, Winger RC, Cruz-Herranz A, Nelson PA, Hagberg S, Miller CN, Spencer CM, Ho PP, Bennett JL, Levy M, Levin MH, Verkman AS, Steinman L, Green AJ, Anderson MS, et al. Tolerance checkpoint bypass permits emergence of pathogenic T cells to neuromyelitis optica autoantigen aquaporin-4. Proceedings of the National Academy of Sciences of the United States of America. PMID 27940915 DOI: 10.1073/Pnas.1617859114 |
0.413 |
|
| 2016 |
Inoue M, Chen PH, Siecinski S, Li QJ, Liu C, Steinman L, Gregory SG, Benner E, Shinohara ML. An interferon-β-resistant and NLRP3 inflammasome-independent subtype of EAE with neuronal damage. Nature Neuroscience. PMID 27820602 DOI: 10.1038/Nn.4421 |
0.382 |
|
| 2016 |
Bar-Or A, Steinman L, Behne JM, Benitez-Ribas D, Chin PS, Clare-Salzler M, Healey D, Kim JI, Kranz DM, Lutterotti A, Martin R, Schippling S, Villoslada P, Wei CH, Weiner HL, et al. Restoring immune tolerance in neuromyelitis optica: Part II. Neurology(R) Neuroimmunology & Neuroinflammation. 3: e277. PMID 27648464 DOI: 10.1212/Nxi.0000000000000277 |
0.381 |
|
| 2016 |
Rovituso DM, Scheffler L, Wunsch M, Kleinschnitz C, Dörck S, Ulzheimer J, Bayas A, Steinman L, Ergün S, Kuerten S. CEACAM1 mediates B cell aggregation in central nervous system autoimmunity. Scientific Reports. 6: 29847. PMID 27435215 DOI: 10.1038/Srep29847 |
0.424 |
|
| 2016 |
Schulze-Topphoff U, Varrin-Doyer M, Pekarek K, Spencer CM, Shetty A, Sagan SA, Cree BA, Sobel RA, Wipke BT, Steinman L, Scannevin RH, Zamvil SS. Dimethyl fumarate treatment induces adaptive and innate immune modulation independent of Nrf2. Proceedings of the National Academy of Sciences of the United States of America. PMID 27078105 DOI: 10.1073/Pnas.1603907113 |
0.438 |
|
| 2016 |
Yu C, Burns JC, Robinson WH, Utz PJ, Ho PP, Steinman L, Frey AB. Identification of Candidate Tolerogenic CD8(+) T Cell Epitopes for Therapy of Type 1 Diabetes in the NOD Mouse Model. Journal of Diabetes Research. 2016: 9083103. PMID 27069933 DOI: 10.1155/2016/9083103 |
0.366 |
|
| 2016 |
Steinman L, Zamvil SS. Beginning of the end of two-stage theory purporting that inflammation then degeneration explains pathogenesis of progressive multiple sclerosis. Current Opinion in Neurology. PMID 27027554 DOI: 10.1097/Wco.0000000000000317 |
0.307 |
|
| 2016 |
Hegen H, Adrianto I, Lessard CJ, Millonig A, Bertolotto A, Comabella M, Giovannoni G, Guger M, Hoelzl M, Khalil M, Fazekas F, Killestein J, Lindberg RL, Malucchi S, Mehling M, ... ... Steinman L, et al. Cytokine profiles show heterogeneity of interferon-β response in multiple sclerosis patients. Neurology® Neuroimmunology & Neuroinflammation. 3: e202. PMID 26894205 DOI: 10.1212/Nxi.0000000000000202 |
0.33 |
|
| 2016 |
Sajda T, Hazelton J, Patel M, Seiffert-Sinha K, Steinman L, Robinson W, Haab BB, Sinha AA. Multiplexed autoantigen microarrays identify HLA as a key driver of anti-desmoglein and -non-desmoglein reactivities in pemphigus. Proceedings of the National Academy of Sciences of the United States of America. PMID 26831096 DOI: 10.1073/Pnas.1525448113 |
0.34 |
|
| 2016 |
Ho PP, Steinman L. Obeticholic acid, a synthetic bile acid agonist of the farnesoid X receptor, attenuates experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. PMID 26811456 DOI: 10.1073/Pnas.1524890113 |
0.382 |
|
| 2016 |
Kuipers HF, Rieck M, Gurevich I, Nagy N, Butte MJ, Negrin RS, Wight TN, Steinman L, Bollyky PL. Hyaluronan synthesis is necessary for autoreactive T-cell trafficking, activation, and Th1 polarization. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787861 DOI: 10.1073/Pnas.1525086113 |
0.452 |
|
| 2016 |
Yiu G, Rasmussen TK, Ajami B, Haddon DJ, Chu AD, Tangsombatvisit S, Haynes WA, Diep V, Steinman L, Faix J, Utz PJ. Development of Th17-Associated Interstitial Kidney Inflammation in Lupus-Prone Mice Lacking the Gene Encoding STAT-1. Arthritis & Rheumatology (Hoboken, N.J.). 68: 1233-44. PMID 26636548 DOI: 10.1002/Art.39535 |
0.302 |
|
| 2015 |
Sotirchos ES, Bhargava P, Eckstein C, Van Haren K, Baynes M, Ntranos A, Gocke A, Steinman L, Mowry EM, Calabresi PA. Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis. Neurology. PMID 26718578 DOI: 10.1212/Wnl.0000000000002316 |
0.306 |
|
| 2015 |
Kurnellas MP, Ghosn EE, Schartner JM, Baker J, Rothbard JJ, Negrin RS, Herzenberg LA, Fathman CG, Steinman L, Rothbard JB. Amyloid fibrils activate B-1a lymphocytes to ameliorate inflammatory brain disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 26621719 DOI: 10.1073/Pnas.1521206112 |
0.349 |
|
| 2015 |
Schaffert SA, Loh C, Wang S, Arnold CP, Axtell RC, Newell EW, Nolan G, Ansel KM, Davis MM, Steinman L, Chen CZ. mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function. Journal of Immunology (Baltimore, Md. : 1950). PMID 26163591 DOI: 10.4049/Jimmunol.1401587 |
0.313 |
|
| 2015 |
van Strien ME, de Vries HE, Chrobok NL, Bol JG, Breve JJ, van der Pol SM, Kooij G, van Buul JD, Karpuj M, Steinman L, Wilhelmus MM, Sestito C, Drukarch B, Van Dam AM. Tissue Transglutaminase contributes to experimental multiple sclerosis pathogenesis and clinical outcome by promoting macrophage migration. Brain, Behavior, and Immunity. PMID 26133787 DOI: 10.1016/J.Bbi.2015.06.023 |
0.407 |
|
| 2015 |
Blaho VA, Galvani S, Engelbrecht E, Liu C, Swendeman SL, Kono M, Proia RL, Steinman L, Han MH, Hla T. HDL-bound sphingosine-1-phosphate restrains lymphopoiesis and neuroinflammation. Nature. 523: 342-6. PMID 26053123 DOI: 10.1038/Nature14462 |
0.631 |
|
| 2015 |
Berkovich R, Togasaki DM, Cen SY, Steinman L. CD4 cell response to interval therapy with natalizumab. Annals of Clinical and Translational Neurology. 2: 570-4. PMID 26000328 DOI: 10.1002/Acn3.190 |
0.338 |
|
| 2015 |
Kurnellas MP, Rothbard JB, Steinman L. Self-Assembling Peptides Form Immune Suppressive Amyloid Fibrils Effective in Autoimmune Encephalomyelitis. Current Topics in Behavioral Neurosciences. 26: 221-32. PMID 25981913 DOI: 10.1007/7854_2015_377 |
0.389 |
|
| 2015 |
Steinman L. The re-emergence of antigen-specific tolerance as a potential therapy for MS. Multiple Sclerosis (Houndmills, Basingstoke, England). 21: 1223-38. PMID 25921045 DOI: 10.1177/1352458515581441 |
0.407 |
|
| 2015 |
Abou-Hamdan M, Costanza M, Fontana E, Di Dario M, Musio S, Congiu C, Onnis V, Lattanzi R, Radaelli M, Martinelli V, Salvadori S, Negri L, Poliani PL, Farina C, Balboni G, ... Steinman L, et al. Critical role for prokineticin 2 in CNS autoimmunity. Neurology® Neuroimmunology & Neuroinflammation. 2: e95. PMID 25884014 DOI: 10.1212/Nxi.0000000000000095 |
0.461 |
|
| 2015 |
Steinman L. No quiet surrender: molecular guardians in multiple sclerosis brain. The Journal of Clinical Investigation. 125: 1371-8. PMID 25831441 DOI: 10.1172/Jci74255 |
0.402 |
|
| 2015 |
Schubert RD, Hu Y, Kumar G, Szeto S, Abraham P, Winderl J, Guthridge JM, Pardo G, Dunn J, Steinman L, Axtell RC. IFN-β treatment requires B cells for efficacy in neuroautoimmunity. Journal of Immunology (Baltimore, Md. : 1950). 194: 2110-6. PMID 25646307 DOI: 10.4049/Jimmunol.1402029 |
0.333 |
|
| 2015 |
Steinman L. Role reversal: infiltrating T cells protect the brain. The Journal of Clinical Investigation. 125: 493-4. PMID 25607835 DOI: 10.1172/Jci80279 |
0.361 |
|
| 2015 |
Costanza M, Binart N, Steinman L, Pedotti R. Prolactin: a versatile regulator of inflammation and autoimmune pathology. Autoimmunity Reviews. 14: 223-30. PMID 25462579 DOI: 10.1016/J.Autrev.2014.11.005 |
0.377 |
|
| 2014 |
Steinman L. Conflicting consequences of immunity to cancer versus autoimmunity to neurons: insights from paraneoplastic disease. European Journal of Immunology. 44: 3201-5. PMID 25319369 DOI: 10.1002/Eji.201445191 |
0.353 |
|
| 2014 |
Steinman L, Shoenfeld Y. From defining antigens to new therapies in multiple sclerosis: honoring the contributions of Ruth Arnon and Michael Sela. Journal of Autoimmunity. 54: 1-7. PMID 25308417 DOI: 10.1016/J.Jaut.2014.08.001 |
0.381 |
|
| 2014 |
Costanza M, Di Dario M, Steinman L, Farina C, Pedotti R. Gene expression analysis of histamine receptors in peripheral blood mononuclear cells from individuals with clinically-isolated syndrome and different stages of multiple sclerosis. Journal of Neuroimmunology. 277: 186-8. PMID 25293806 DOI: 10.1016/J.Jneuroim.2014.09.018 |
0.363 |
|
| 2014 |
Steinman L. Why are prions and amyloid structures immune suppressive and other intriguing questions facing neuroimmunologists in the future. Revue Neurologique. 170: 602-607. PMID 25193013 DOI: 10.1016/J.Neurol.2014.07.011 |
0.387 |
|
| 2014 |
Meyer zu Horste G, Mausberg AK, Cordes S, El-Haddad H, Partke HJ, Leussink VI, Roden M, Martin S, Steinman L, Hartung HP, Kieseier BC. Thymic epithelium determines a spontaneous chronic neuritis in Icam1(tm1Jcgr)NOD mice. Journal of Immunology (Baltimore, Md. : 1950). 193: 2678-90. PMID 25108020 DOI: 10.4049/Jimmunol.1400367 |
0.378 |
|
| 2014 |
Kurnellas MP, Schartner JM, Fathman CG, Jagger A, Steinman L, Rothbard JB. Mechanisms of action of therapeutic amyloidogenic hexapeptides in amelioration of inflammatory brain disease. The Journal of Experimental Medicine. 211: 1847-56. PMID 25073790 DOI: 10.1084/Jem.20140107 |
0.362 |
|
| 2014 |
Steinman L. Development of therapies for autoimmune disease at Stanford: a tale of multiple shots and one goal. Immunologic Research. 58: 307-14. PMID 24771483 DOI: 10.1007/S12026-014-8509-0 |
0.418 |
|
| 2014 |
Steinman L, Rothbard JB, Kurnellas MP. Janus faces of amyloid proteins in neuroinflammation. Journal of Clinical Immunology. 34: S61-3. PMID 24711007 DOI: 10.1007/S10875-014-0034-3 |
0.325 |
|
| 2014 |
Wang D, Bhat R, Sobel RA, Huang W, Wang LX, Olsson T, Steinman L. Uncovering cryptic glycan markers in multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE). Drug Development Research. 75: 172-88. PMID 24648292 DOI: 10.1002/Ddr.21169 |
0.425 |
|
| 2014 |
Weber MS, Prod'homme T, Youssef S, Dunn SE, Steinman L, Zamvil SS. Neither T-helper type 2 nor Foxp3+ regulatory T cells are necessary for therapeutic benefit of atorvastatin in treatment of central nervous system autoimmunity. Journal of Neuroinflammation. 11: 29. PMID 24498870 DOI: 10.1186/1742-2094-11-29 |
0.439 |
|
| 2014 |
Ding Z, Mathur V, Ho PP, James ML, Lucin KM, Hoehne A, Alabsi H, Gambhir SS, Steinman L, Luo J, Wyss-Coray T. Antiviral drug ganciclovir is a potent inhibitor of microglial proliferation and neuroinflammation. The Journal of Experimental Medicine. 211: 189-98. PMID 24493798 DOI: 10.1084/Jem.20120696 |
0.443 |
|
| 2014 |
Steinman L. Immunology of relapse and remission in multiple sclerosis. Annual Review of Immunology. 32: 257-81. PMID 24438352 DOI: 10.1146/Annurev-Immunol-032713-120227 |
0.374 |
|
| 2014 |
Bruinsma I, Eijsink V, Kooi EJ, Baranzini S, Ji XH, Axtell R, Han M, Kuipers H, Sobel R, Polman C, Geurts J, Martens GJM, Poelmans G, Steinman L, Jong BD. Genome-wide RNA expression profiling in human grey and white matter tissue reveals a role for PSA-NCAM dysregulation in MS pathogenesis Journal of Neuroimmunology. 275: 180-181. DOI: 10.1016/J.Jneuroim.2014.08.485 |
0.63 |
|
| 2014 |
Kuipers HF, Yoon J, Winderl J, Horssen JV, Han MH, Palmer TD, Steinman L. Differential phosphorylation of alpha B-crystallin in astrocytes and oligodendrocytes suggests a diversity in its biological function Journal of Neuroimmunology. 275: 157-158. DOI: 10.1016/J.Jneuroim.2014.08.423 |
0.598 |
|
| 2014 |
Costanza M, Dario MD, Steinman L, Farina C, Pedotti R. Gene expression analysis of histamine receptors in peripheral blood mononuclear cells from clinically-isolated syndrome and multiple sclerosis patients Journal of Neuroimmunology. 275: 146. DOI: 10.1016/J.Jneuroim.2014.08.390 |
0.383 |
|
| 2014 |
Abou-hamdan M, Costanza M, Fontana E, Musio S, Dario MD, Congiu C, Onnis V, Lattanzi R, Negri L, Poliani PL, Farina C, Balboni G, Steinman L, Pedotti R. An important role for prokineticin 2 in autoimmune CNS demyelination Journal of Neuroimmunology. 275: 131-131. DOI: 10.1016/J.Jneuroim.2014.08.352 |
0.347 |
|
| 2014 |
Kuipers HF, Rieck M, Steinman L, Bollyky PL. The role of hyaluronan and 4-methylumbelliferone treatment in multiple sclerosis Journal of Neuroimmunology. 275: 64-65. DOI: 10.1016/J.Jneuroim.2014.08.170 |
0.327 |
|
| 2013 |
Gottlieb P, Utz PJ, Robinson W, Steinman L. Clinical optimization of antigen specific modulation of type 1 diabetes with the plasmid DNA platform. Clinical Immunology (Orlando, Fla.). 149: 297-306. PMID 24094739 DOI: 10.1016/J.Clim.2013.08.010 |
0.319 |
|
| 2013 |
Garris CS, Wu L, Acharya S, Arac A, Blaho VA, Huang Y, Moon BS, Axtell RC, Ho PP, Steinberg GK, Lewis DB, Sobel RA, Han DK, Steinman L, Snyder MP, et al. Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation. Nature Immunology. 14: 1166-72. PMID 24076635 DOI: 10.1038/Ni.2730 |
0.67 |
|
| 2013 |
Steinman L. Pathogenic T helper 1 cells reach the brain before T helper 17 cells, and T regulatory cells suppress them albeit incompletely. Acta Neuropathologica. 126: 517-8. PMID 24045898 DOI: 10.1007/S00401-013-1180-Z |
0.341 |
|
| 2013 |
Naves R, Singh SP, Cashman KS, Rowse AL, Axtell RC, Steinman L, Mountz JD, Steele C, De Sarno P, Raman C. The interdependent, overlapping, and differential roles of type I and II IFNs in the pathogenesis of experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 191: 2967-77. PMID 23960239 DOI: 10.4049/Jimmunol.1300419 |
0.346 |
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| 2013 |
Steinman L. The road not taken: antigen-specific therapy and neuroinflammatory disease. Jama Neurology. 70: 1100-1. PMID 23817885 DOI: 10.1001/Jamaneurol.2013.3553 |
0.309 |
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| 2013 |
Roep BO, Solvason N, Gottlieb PA, Abreu JR, Harrison LC, Eisenbarth GS, Yu L, Leviten M, Hagopian WA, Buse JB, von Herrath M, Quan J, King RS, Robinson WH, Utz PJ, ... ... Steinman L, et al. Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8⺠T cells in type 1 diabetes. Science Translational Medicine. 5: 191ra82. PMID 23803704 DOI: 10.1089/Dia.2014.1510 |
0.375 |
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| 2013 |
Davidson MG, Alonso MN, Yuan R, Axtell RC, Kenkel JA, Suhoski MM, González JC, Steinman L, Engleman EG. Th17 cells induce Th1-polarizing monocyte-derived dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 191: 1175-87. PMID 23794631 DOI: 10.4049/Jimmunol.1203201 |
0.35 |
|
| 2013 |
Quach QL, Metz LM, Thomas JC, Rothbard JB, Steinman L, Ousman SS. CRYAB modulates the activation of CD4+ T cells from relapsing-remitting multiple sclerosis patients. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 1867-77. PMID 23736536 DOI: 10.1177/1352458513489853 |
0.422 |
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| 2013 |
Marabelle A, Kohrt H, Sagiv-Barfi I, Ajami B, Axtell RC, Zhou G, Rajapaksa R, Green MR, Torchia J, Brody J, Luong R, Rosenblum MD, Steinman L, Levitsky HI, Tse V, et al. Depleting tumor-specific Tregs at a single site eradicates disseminated tumors. The Journal of Clinical Investigation. 123: 2447-63. PMID 23728179 DOI: 10.1172/Jci73340 |
0.308 |
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| 2013 |
Rafalski VA, Ho PP, Brett JO, Ucar D, Dugas JC, Pollina EA, Chow LM, Ibrahim A, Baker SJ, Barres BA, Steinman L, Brunet A. Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain. Nature Cell Biology. 15: 614-24. PMID 23644469 DOI: 10.1038/Ncb2735 |
0.335 |
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| 2013 |
Van Haren K, Tomooka BH, Kidd BA, Banwell B, Bar-Or A, Chitnis T, Tenembaum SN, Pohl D, Rostasy K, Dale RC, O'Connor KC, Hafler DA, Steinman L, Robinson WH. Serum autoantibodies to myelin peptides distinguish acute disseminated encephalomyelitis from relapsing-remitting multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 1726-33. PMID 23612879 DOI: 10.1177/1352458513485653 |
0.393 |
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| 2013 |
Kurnellas MP, Adams CM, Sobel RA, Steinman L, Rothbard JB. Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation. Science Translational Medicine. 5: 179ra42. PMID 23552370 DOI: 10.1126/Scitranslmed.3005681 |
0.322 |
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| 2013 |
Gnanapavan S, Ho P, Heywood W, Jackson S, Grant D, Rantell K, Keir G, Mills K, Steinman L, Giovannoni G. Progression in multiple sclerosis is associated with low endogenous NCAM. Journal of Neurochemistry. 125: 766-73. PMID 23495921 DOI: 10.1111/Jnc.12236 |
0.403 |
|
| 2013 |
Steinman L. A Tip leads cytotoxic T cells to the crime scene in neuroinflammation. Nature Immunology. 14: 196-7. PMID 23416668 DOI: 10.1038/Ni.2551 |
0.375 |
|
| 2013 |
Sarikonda G, Sachithanantham S, Manenkova Y, Kupfer T, Posgai A, Wasserfall C, Bernstein P, Straub L, Pagni PP, Schneider D, Calvo TR, Coulombe M, Herold K, Gill RG, Atkinson M, ... ... Steinman L, et al. Transient B-cell depletion with anti-CD20 in combination with proinsulin DNA vaccine or oral insulin: immunologic effects and efficacy in NOD mice. Plos One. 8: e54712. PMID 23405091 DOI: 10.1371/Journal.Pone.0054712 |
0.31 |
|
| 2013 |
Steinman L. Weighing in on autoimmune disease: 'Hub-and-spoke' T cell traffic in autoimmunity. Nature Medicine. 19: 139-41. PMID 23389609 DOI: 10.1038/Nm.3088 |
0.385 |
|
| 2013 |
Steinman L. Inflammatory cytokines at the summits of pathological signal cascades in brain diseases. Science Signaling. 6: pe3. PMID 23322904 DOI: 10.1126/Scisignal.2003898 |
0.311 |
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| 2013 |
Steinman L, Axtell RC, Barbieri D, Bhat R, Brownell SE, de Jong BA, Dunn SE, Grant JL, Han MH, Ho PP, Kuipers HF, Kurnellas MP, Ousman SS, Rothbard JB. Piet Mondrian's trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 5-14. PMID 23303879 DOI: 10.1177/1352458512470730 |
0.668 |
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| 2013 |
Axtell RC, Raman C, Steinman L. Type I interferons: beneficial in Th1 and detrimental in Th17 autoimmunity. Clinical Reviews in Allergy & Immunology. 44: 114-20. PMID 22231516 DOI: 10.1007/S12016-011-8296-5 |
0.404 |
|
| 2012 |
Steinman L. The discovery of natalizumab, a potent therapeutic for multiple sclerosis. The Journal of Cell Biology. 199: 413-6. PMID 23109666 DOI: 10.1083/Jcb.201207175 |
0.426 |
|
| 2012 |
Grant JL, Ghosn EE, Axtell RC, Herges K, Kuipers HF, Woodling NS, Andreasson K, Herzenberg LA, Herzenberg LA, Steinman L. Reversal of paralysis and reduced inflammation from peripheral administration of β-amyloid in TH1 and TH17 versions of experimental autoimmune encephalomyelitis. Science Translational Medicine. 4: 145ra105. PMID 22855462 DOI: 10.1126/Scitranslmed.3004145 |
0.352 |
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| 2012 |
Arellano B, Hussain R, Zacharias T, Yoon J, David C, Zein S, Steinman L, Forsthuber T, Greenberg BM, Lambracht-Washington D, Ritchie AM, Bennett JL, Stüve O. Human aquaporin 4 281-300 is the immunodominant linear determinant in the context of HLA-DRB1*03:01: Relevance for diagnosing and monitoring patients with neuromyelitis optica Archives of Neurology. 69: 1125-1131. PMID 22751865 DOI: 10.1001/Archneurol.2012.1300 |
0.378 |
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| 2012 |
Han MH, Lundgren DH, Jaiswal S, Chao M, Graham KL, Garris CS, Axtell RC, Ho PP, Lock CB, Woodard JI, Brownell SE, Zoudilova M, Hunt JF, Baranzini SE, Butcher EC, ... ... Steinman L, et al. Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice. The Journal of Experimental Medicine. 209: 1325-34. PMID 22734047 DOI: 10.1084/Jem.20101974 |
0.675 |
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| 2012 |
Ho PP, Kanter JL, Johnson AM, Srinagesh HK, Chang EJ, Purdy TM, van Haren K, Wikoff WR, Kind T, Khademi M, Matloff LY, Narayana S, Hur EM, Lindstrom TM, He Z, ... ... Steinman L, et al. Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation. Science Translational Medicine. 4: 137ra73. PMID 22674551 DOI: 10.1126/Scitranslmed.3003831 |
0.791 |
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| 2012 |
Zhang MA, Rego D, Moshkova M, Kebir H, Chruscinski A, Nguyen H, Akkermann R, Stanczyk FZ, Prat A, Steinman L, Dunn SE. Peroxisome proliferator-activated receptor (PPAR)α and -γ regulate IFNγ and IL-17A production by human T cells in a sex-specific way. Proceedings of the National Academy of Sciences of the United States of America. 109: 9505-10. PMID 22647601 DOI: 10.1073/Pnas.1118458109 |
0.349 |
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| 2012 |
Steinman L. Platelets provide a bounty of potential targets for therapy in multiple sclerosis. Circulation Research. 110: 1157-8. PMID 22539752 DOI: 10.1161/Circresaha.112.269050 |
0.39 |
|
| 2012 |
Herges K, de Jong BA, Kolkowitz I, Dunn C, Mandelbaum G, Ko RM, Maini A, Han MH, Killestein J, Polman C, Goodyear AL, Dunn J, Steinman L, Axtell RC. Protective effect of an elastase inhibitor in a neuromyelitis optica-like disease driven by a peptide of myelin oligodendroglial glycoprotein. Multiple Sclerosis (Houndmills, Basingstoke, England). 18: 398-408. PMID 22343184 DOI: 10.1177/1352458512440060 |
0.673 |
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| 2012 |
Steinman L, Merrill JT, McInnes IB, Peakman M. Optimization of current and future therapy for autoimmune diseases. Nature Medicine. 18: 59-65. PMID 22227674 DOI: 10.1038/Nm.2625 |
0.34 |
|
| 2012 |
Papadopoulou A, von Felten S, Traud S, Rahman A, Quan J, King R, Garren H, Steinman L, Cutter G, Kappos L, Radue EW. Evolution of MS lesions to black holes under DNA vaccine treatment. Journal of Neurology. 259: 1375-82. PMID 22222856 DOI: 10.1007/S00415-011-6361-X |
0.345 |
|
| 2011 |
Zhuang X, Xiang X, Grizzle W, Sun D, Zhang S, Axtell RC, Ju S, Mu J, Zhang L, Steinman L, Miller D, Zhang HG. Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1769-79. PMID 21915101 DOI: 10.1038/Mt.2011.164 |
0.328 |
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| 2011 |
Itoh S, Kimura N, Axtell RC, Velotta JB, Gong Y, Wang X, Kajiwara N, Nambu A, Shimura E, Adachi H, Iwakura Y, Saito H, Okumura K, Sudo K, Steinman L, et al. Interleukin-17 accelerates allograft rejection by suppressing regulatory T cell expansion. Circulation. 124: S187-96. PMID 21911812 DOI: 10.1161/Circulationaha.110.014852 |
0.313 |
|
| 2011 |
Noorbakhsh F, Ellestad KK, Maingat F, Warren KG, Han MH, Steinman L, Baker GB, Power C. Impaired neurosteroid synthesis in multiple sclerosis. Brain : a Journal of Neurology. 134: 2703-21. PMID 21908875 DOI: 10.1093/Brain/Awr200 |
0.653 |
|
| 2011 |
Crespo O, Kang SC, Daneman R, Lindstrom TM, Ho PP, Sobel RA, Steinman L, Robinson WH. Tyrosine kinase inhibitors ameliorate autoimmune encephalomyelitis in a mouse model of multiple sclerosis. Journal of Clinical Immunology. 31: 1010-20. PMID 21847523 DOI: 10.1007/S10875-011-9579-6 |
0.424 |
|
| 2011 |
Joshi S, Pantalena LC, Liu XK, Gaffen SL, Liu H, Rohowsky-Kochan C, Ichiyama K, Yoshimura A, Steinman L, Christakos S, Youssef S. 1,25-dihydroxyvitamin D(3) ameliorates Th17 autoimmunity via transcriptional modulation of interleukin-17A. Molecular and Cellular Biology. 31: 3653-69. PMID 21746882 DOI: 10.1128/Mcb.05020-11 |
0.346 |
|
| 2011 |
Zamvil SS, Steinman L. Combining statins with interferon β in multiple sclerosis: think twice, it might not be all right. The Lancet. Neurology. 10: 672-3. PMID 21742557 DOI: 10.1016/S1474-4422(11)70153-3 |
0.39 |
|
| 2011 |
Axtell RC, Raman C, Steinman L. Interferon-β exacerbates Th17-mediated inflammatory disease. Trends in Immunology. 32: 272-7. PMID 21530402 DOI: 10.1016/J.It.2011.03.008 |
0.349 |
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| 2011 |
Rothbard JB, Zhao X, Sharpe O, Strohman MJ, Kurnellas M, Mellins ED, Robinson WH, Steinman L. Chaperone activity of α B-crystallin is responsible for its incorrect assignment as an autoantigen in multiple sclerosis. Journal of Immunology (Baltimore, Md. : 1950). 186: 4263-8. PMID 21357544 DOI: 10.4049/Jimmunol.1003934 |
0.353 |
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| 2011 |
Kornum BR, Kawashima M, Faraco J, Lin L, Rico TJ, Hesselson S, Axtell RC, Kuipers H, Weiner K, Hamacher A, Kassack MU, Han F, Knudsen S, Li J, Dong X, ... ... Steinman L, et al. Common variants in P2RY11 are associated with narcolepsy. Nature Genetics. 43: 66-71. PMID 21170044 DOI: 10.1038/Ng.734 |
0.347 |
|
| 2011 |
Lapilla M, Gallo B, Martinello M, Procaccini C, Costanza M, Musio S, Rossi B, Angiari S, Farina C, Steinman L, Matarese G, Constantin G, Pedotti R. Histamine regulates autoreactive T cell activation and adhesiveness in inflamed brain microcirculation. Journal of Leukocyte Biology. 89: 259-67. PMID 21071626 DOI: 10.1189/Jlb.0910486 |
0.405 |
|
| 2011 |
Berkovich R, Subhani D, Steinman L. Autoimmune Comorbid Conditions in Multiple Sclerosis Us Neurology. 7: 132. DOI: 10.17925/Usn.2011.07.02.132 |
0.347 |
|
| 2010 |
Steinman L, Zamvil SS. Delivery of myelin peptides through the first line of defense, skin, to counter autoimmunity in multiple sclerosis. Annals of Neurology. 68: 567-9. PMID 21031570 DOI: 10.1002/Ana.22255 |
0.316 |
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| 2010 |
Lanz TV, Ding Z, Ho PP, Luo J, Agrawal AN, Srinagesh H, Axtell R, Zhang H, Platten M, Wyss-Coray T, Steinman L. Angiotensin II sustains brain inflammation in mice via TGF-beta. The Journal of Clinical Investigation. 120: 2782-94. PMID 20628203 DOI: 10.1172/Jci41709 |
0.34 |
|
| 2010 |
Dunn SE, Bhat R, Straus DS, Sobel RA, Axtell R, Johnson A, Nguyen K, Mukundan L, Moshkova M, Dugas JC, Chawla A, Steinman L. Peroxisome proliferator-activated receptor delta limits the expansion of pathogenic Th cells during central nervous system autoimmunity. The Journal of Experimental Medicine. 207: 1599-608. PMID 20624891 DOI: 10.1084/Jem.20091663 |
0.386 |
|
| 2010 |
van Noort JM, Bsibsi M, Gerritsen WH, van der Valk P, Bajramovic JJ, Steinman L, Amor S. Alphab-crystallin is a target for adaptive immune responses and a trigger of innate responses in preactive multiple sclerosis lesions. Journal of Neuropathology and Experimental Neurology. 69: 694-703. PMID 20535035 DOI: 10.1097/Nen.0B013E3181E4939C |
0.391 |
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| 2010 |
Steinman L. Inverse vaccination, the opposite of Jenner’s concept, for therapy of autoimmunity Journal of Internal Medicine. 267: 441-451. PMID 20433574 DOI: 10.1111/J.1365-2796.2010.02224.X |
0.343 |
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| 2010 |
Kleiter I, Song J, Lukas D, Hasan M, Neumann B, Croxford AL, Pedré X, Hövelmeyer N, Yogev N, Mildner A, Prinz M, Wiese E, Reifenberg K, Bittner S, Wiendl H, ... Steinman L, et al. Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis. Brain : a Journal of Neurology. 133: 1067-81. PMID 20354004 DOI: 10.1093/Brain/Awq039 |
0.389 |
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| 2010 |
Axtell RC, de Jong BA, Boniface K, van der Voort LF, Bhat R, De Sarno P, Naves R, Han M, Zhong F, Castellanos JG, Mair R, Christakos A, Kolkowitz I, Katz L, Killestein J, ... ... Steinman L, et al. T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis. Nature Medicine. 16: 406-12. PMID 20348925 DOI: 10.1038/Nm.2110 |
0.652 |
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| 2010 |
Langer-Gould A, Gupta R, Huang S, Hagan A, Atkuri K, Leimpeter AD, Albers KB, Greenwood E, Van Den Eeden SK, Steinman L, Nelson LM. Interferon-gamma-producing T cells, pregnancy, and postpartum relapses of multiple sclerosis. Archives of Neurology. 67: 51-7. PMID 20065129 DOI: 10.1001/Archneurol.2009.304 |
0.347 |
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| 2010 |
Steinman L. Mixed results with modulation of TH-17 cells in human autoimmune diseases Nature Immunology. 11: 41-44. PMID 20016509 DOI: 10.1038/Ni.1803 |
0.367 |
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| 2010 |
Ho PP, Lee LY, Zhao X, Tomooka BH, Paniagua RT, Sharpe O, BenBarak MJ, Chandra PE, Hueber W, Steinman L, Robinson WH. Autoimmunity against fibrinogen mediates inflammatory arthritis in mice. Journal of Immunology (Baltimore, Md. : 1950). 184: 379-90. PMID 19949094 DOI: 10.4049/Jimmunol.0901639 |
0.365 |
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| 2010 |
Lanz TV, Opitz CA, Ho PP, Agrawal A, Lutz C, Weller M, Mellor AL, Steinman L, Wick W, Platten M. Mouse mesenchymal stem cells suppress antigen-specific TH cell immunity independent of indoleamine 2,3-dioxygenase 1 (IDO1). Stem Cells and Development. 19: 657-68. PMID 19886804 DOI: 10.1089/Scd.2009.0385 |
0.448 |
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| 2010 |
Graham KL, Lee LY, Higgins JP, Steinman L, Utz PJ, Ho PP. Treatment with a toll-like receptor inhibitory GpG oligonucleotide delays and attenuates lupus nephritis in NZB/W mice. Autoimmunity. 43: 140-55. PMID 19845477 DOI: 10.3109/08916930903229239 |
0.348 |
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| 2010 |
Naves R, Singh S, De Sarno P, Cashman K, Axtell R, Steinman L, Raman C. Distinctive and Cooperative Role of Type I and Type II Interferons in the Pathogenesis of TH1 and TH17 Cells in Autoimmune Neuroinflammation Clinical Immunology. 135: S29-S30. DOI: 10.1016/J.Clim.2010.03.092 |
0.316 |
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| 2009 |
Bhat R, Steinman L. Innate and Adaptive Autoimmunity Directed to the Central Nervous System Neuron. 64: 123-132. PMID 19840554 DOI: 10.1016/J.Neuron.2009.09.015 |
0.395 |
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| 2009 |
Platten M, Youssef S, Hur EM, Ho PP, Han MH, Lanz TV, Phillips LK, Goldstein MJ, Bhat R, Raine CS, Sobel RA, Steinman L. Blocking angiotensin-converting enzyme induces potent regulatory T cells and modulates TH1- and TH17-mediated autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 106: 14948-53. PMID 19706421 DOI: 10.1073/Pnas.0903958106 |
0.807 |
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| 2009 |
Steinman L. Shifting therapeutic attention in MS to osteopontin, type 1 and type 2 IFN European Journal of Immunology. 39: 2358-2360. PMID 19681057 DOI: 10.1002/Eji.200939814 |
0.376 |
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| 2009 |
Schulze-Topphoff U, Prat A, Prozorovski T, Siffrin V, Paterka M, Herz J, Bendix I, Ifergan I, Schadock I, Mori MA, Van Horssen J, Schröter F, Smorodchenko A, Han MH, Bader M, ... Steinman L, et al. Activation of kinin receptor B1 limits encephalitogenic T lymphocyte recruitment to the central nervous system. Nature Medicine. 15: 788-93. PMID 19561616 DOI: 10.1038/Nm.1980 |
0.71 |
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| 2009 |
Steinman L. The gray aspects of white matter disease in multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. 106: 8083-8084. PMID 19451620 DOI: 10.1073/Pnas.0903377106 |
0.394 |
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| 2009 |
Steinman L. A molecular trio in relapse and remission in multiple sclerosis Nature Reviews Immunology. 9: 440-447. PMID 19444308 DOI: 10.1038/Nri2548 |
0.377 |
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| 2009 |
Han MH, Steinman L. Systems biology for identification of molecular networks in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 15: 529-30. PMID 19389747 DOI: 10.1177/1352458509103318 |
0.613 |
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| 2009 |
Axtell RC, Steinman L. Gaining entry to an uninflamed brain. Nature Immunology. 10: 453-5. PMID 19381137 DOI: 10.1038/Ni0509-453 |
0.386 |
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| 2009 |
Newsom-Davis TE, Wang D, Steinman L, Chen PF, Wang LX, Simon AK, Screaton GR. Enhanced immune recognition of cryptic glycan markers in human tumors. Cancer Research. 69: 2018-25. PMID 19223535 DOI: 10.1158/0008-5472.Can-08-3589 |
0.325 |
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| 2009 |
Zeiser R, Maas K, Youssef S, Dürr C, Steinman L, Negrin RS. Regulation of different inflammatory diseases by impacting the mevalonate pathway. Immunology. 127: 18-25. PMID 19191903 DOI: 10.1111/J.1365-2567.2008.03011.X |
0.38 |
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| 2009 |
Musio S, Pedotti P, Mantegazza R, Ohtsu H, Boon L, Steinman L, Galli SJ, Pedotti R. Anaphylaxis to a self-peptide in the absence of mast cells or histamine. Laboratory Investigation; a Journal of Technical Methods and Pathology. 89: 398-405. PMID 19188909 DOI: 10.1038/Labinvest.2009.4 |
0.343 |
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| 2009 |
Brownell S, Rothbard J, Steinman L. T.130. Small Heat Shock Proteins as Novel Therapeutic Treatments for Autoimmune Diseases Clinical Immunology. 131. DOI: 10.1016/J.Clim.2009.03.263 |
0.321 |
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| 2009 |
Crespo O, Kang S, Daneman R, Sobel R, Ho P, Steinman L, Robinson W. T.77. Tyrosine Kinases in Autoimmune Demyelination Clinical Immunology. 131: S73. DOI: 10.1016/J.Clim.2009.03.212 |
0.311 |
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| 2008 |
Solvason N, Lou YP, Peters W, Evans E, Martinez J, Ramirez U, Ocampo A, Yun R, Ahmad S, Liu E, Yu L, Eisenbarth G, Leviten M, Steinman L, Garren H. Improved efficacy of a tolerizing DNA vaccine for reversal of hyperglycemia through enhancement of gene expression and localization to intracellular sites. Journal of Immunology (Baltimore, Md. : 1950). 181: 8298-307. PMID 19050246 DOI: 10.4049/Jimmunol.181.12.8298 |
0.317 |
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| 2008 |
Steinman L. Nuanced roles of cytokines in three major human brain disorders Journal of Clinical Investigation. 118: 3557-3563. PMID 18982162 DOI: 10.1172/Jci36532 |
0.385 |
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| 2008 |
Kidd BA, Ho PP, Sharpe O, Zhao X, Tomooka BH, Kanter JL, Steinman L, Robinson WH. Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination. Arthritis Research & Therapy. 10: R119. PMID 18826638 DOI: 10.1186/Ar2523 |
0.321 |
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| 2008 |
Steinman L. New targets for treatment of multiple sclerosis. Journal of the Neurological Sciences. 274: 1-4. PMID 18768188 DOI: 10.1016/J.Jns.2008.06.040 |
0.335 |
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| 2008 |
Steinman L. A rush to judgment on Th17 Journal of Experimental Medicine. 205: 1517-1522. PMID 18591407 DOI: 10.1084/Jem.20072066 |
0.376 |
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| 2008 |
Jensen KD, Su X, Shin S, Li L, Youssef S, Yamasaki S, Steinman L, Saito T, Locksley RM, Davis MM, Baumgarth N, Chien YH. Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma. Immunity. 29: 90-100. PMID 18585064 DOI: 10.1016/J.Immuni.2008.04.022 |
0.384 |
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| 2008 |
Graham KL, Lee LY, Higgins JP, Steinman L, Utz PJ, Ho PP. Failure of oral atorvastatin to modulate a murine model of systemic lupus erythematosus. Arthritis and Rheumatism. 58: 2098-104. PMID 18576356 DOI: 10.1002/Art.23605 |
0.308 |
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| 2008 |
Axtell RC, Steinman L. Type 1 interferons cool the inflamed brain. Immunity. 28: 600-2. PMID 18482563 DOI: 10.1016/J.Immuni.2008.04.006 |
0.306 |
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| 2008 |
Garren H, Robinson WH, Krasulová E, Havrdová E, Nadj C, Selmaj K, Losy J, Nadj I, Radue EW, Kidd BA, Gianettoni J, Tersini K, Utz PJ, Valone F, Steinman L, et al. Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis. Annals of Neurology. 63: 611-20. PMID 18481290 DOI: 10.1002/Ana.21370 |
0.361 |
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| 2008 |
Scabeni S, Lapilla M, Musio S, Gallo B, Ciusani E, Steinman L, Mantegazza R, Pedotti R. CD4+CD25+ regulatory T cells specific for a thymus-expressed antigen prevent the development of anaphylaxis to self. Journal of Immunology. 180: 4433-4440. PMID 18354164 DOI: 10.4049/Jimmunol.180.7.4433 |
0.315 |
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| 2008 |
Han MH, Hwang SI, Roy DB, Lundgren DH, Price JV, Ousman SS, Fernald GH, Gerlitz B, Robinson WH, Baranzini SE, Grinnell BW, Raine CS, Sobel RA, Han DK, Steinman L. Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets. Nature. 451: 1076-81. PMID 18278032 DOI: 10.1038/Nature06559 |
0.684 |
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| 2008 |
Luo J, Ho P, Steinman L, Wyss-Coray T. Bioluminescence in vivo imaging of autoimmune encephalomyelitis predicts disease. Journal of Neuroinflammation. 5: 6. PMID 18237444 DOI: 10.1186/1742-2094-5-6 |
0.342 |
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| 2008 |
Ho P, Kanter J, Johnson A, Steinman L, Robinson W. OR.58. Lipids as Autoantigens and Therapeutic Immune Modulators in Autoimmune Demyelination Clinical Immunology. 127: S24-S25. DOI: 10.1016/J.Clim.2008.03.064 |
0.336 |
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| 2007 |
Luo J, Ho PP, Buckwalter MS, Hsu T, Lee LY, Zhang H, Kim DK, Kim SJ, Gambhir SS, Steinman L, Wyss-Coray T. Glia-dependent TGF-beta signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis. The Journal of Clinical Investigation. 117: 3306-15. PMID 17965773 DOI: 10.1172/Jci31763 |
0.357 |
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| 2007 |
Weber MS, Steinman L, Zamvil SS. Statins—Treatment option for central nervous system autoimmune disease? Neurotherapeutics. 4: 693-700. PMID 17920550 DOI: 10.1016/J.Nurt.2007.08.004 |
0.37 |
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| 2007 |
Steinman L. Antigen-specific therapy of multiple sclerosis: The long-sought magic bullet Neurotherapeutics. 4: 661-665. PMID 17920547 DOI: 10.1016/J.Nurt.2007.07.007 |
0.423 |
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| 2007 |
Kaper T, Looger LL, Takanaga H, Platten M, Steinman L, Frommer WB. Nanosensor detection of an immunoregulatory tryptophan influx/kynurenine efflux cycle. Plos Biology. 5: e257. PMID 17896864 DOI: 10.1371/Journal.Pbio.0050257 |
0.303 |
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| 2007 |
Zeiser R, Youssef S, Baker J, Kambham N, Steinman L, Negrin RS. Preemptive HMG-CoA reductase inhibition provides graft-versus-host disease protection by Th-2 polarization while sparing graft-versus-leukemia activity. Blood. 110: 4588-4598. PMID 17827390 DOI: 10.1182/Blood-2007-08-106005 |
0.352 |
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| 2007 |
Bar-Or A, Vollmer T, Antel J, Arnold DL, Bodner CA, Campagnolo D, Gianettoni J, Jalili F, Kachuck N, Lapierre Y, Niino M, Oger J, Price M, Rhodes S, Robinson WH, ... ... Steinman L, et al. Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial. Archives of Neurology. 64: 1407-15. PMID 17698695 DOI: 10.1001/Archneur.64.10.Nct70002 |
0.394 |
|
| 2007 |
Weber MS, Prod'homme T, Youssef S, Dunn SE, Rundle CD, Lee L, Patarroyo JC, Stüve O, Sobel RA, Steinman L, Zamvil SS. Type II monocytes modulate T cell-mediated central nervous system autoimmune disease. Nature Medicine. 13: 935-43. PMID 17676050 DOI: 10.1038/Nm1620 |
0.419 |
|
| 2007 |
Opitz CA, Wick W, Steinman L, Platten M. Tryptophan degradation in autoimmune diseases. Cellular and Molecular Life Sciences : Cmls. 64: 2542-63. PMID 17611712 DOI: 10.1007/S00018-007-7140-9 |
0.337 |
|
| 2007 |
Ousman SS, Tomooka BH, van Noort JM, Wawrousek EF, O'Connor KC, Hafler DA, Sobel RA, Robinson WH, Steinman L. Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination. Nature. 448: 474-9. PMID 17568699 DOI: 10.1038/Nature05935 |
0.468 |
|
| 2007 |
Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nature Medicine. 13: 139-145. PMID 17290272 DOI: 10.1038/Nm1551 |
0.369 |
|
| 2007 |
Dunn SE, Ousman SS, Sobel RA, Zuniga L, Baranzini SE, Youssef S, Crowell A, Loh J, Oksenberg J, Steinman L. Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. The Journal of Experimental Medicine. 204: 321-30. PMID 17261635 DOI: 10.1084/Jem.20061839 |
0.39 |
|
| 2007 |
Chora AA, Fontoura P, Cunha A, Pais TF, Cardoso S, Ho PP, Lee LY, Sobel RA, Steinman L, Soares MP. Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation. The Journal of Clinical Investigation. 117: 438-47. PMID 17256058 DOI: 10.1172/Jci28844 |
0.392 |
|
| 2007 |
O'Connor KC, McLaughlin KA, De Jager PL, Chitnis T, Bettelli E, Xu C, Robinson WH, Cherry SV, Bar-Or A, Banwell B, Fukaura H, Fukazawa T, Tenembaum S, Wong SJ, Tavakoli NP, ... ... Steinman L, et al. Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein. Nature Medicine. 13: 211-7. PMID 17237795 DOI: 10.1038/Nm1488 |
0.383 |
|
| 2007 |
Hur EM, Youssef S, Haws ME, Zhang SY, Sobel RA, Steinman L. Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. Nature Immunology. 8: 74-83. PMID 17143274 DOI: 10.1038/Ni1415 |
0.778 |
|
| 2007 |
Fontoura P, Steinman L, Miller A. Emerging therapeutic targets in multiple sclerosis. Current Opinion in Neurology. 19: 260-6. PMID 16702832 DOI: 10.1097/01.Wco.0000227035.93199.E0 |
0.341 |
|
| 2007 |
Dunn S, Ousman S, Sobel R, Baranzini S, Zuniga L, Youssef S, Oksenberg J, Steinman L. Peroxisome Poliferator-activated Receptor-α (PPARα) Expression in T Cells Mediates Gender Differences in Development of T Cell-mediated Autoimmunity Clinical Immunology. 123: S74. DOI: 10.1016/J.Clim.2007.03.390 |
0.345 |
|
| 2007 |
Han MH, Hwang S, Roy D, Raine C, Robinson WH, Sobel RA, Han D, Steinman L. Proteomic Profiling of Multiple Sclerosis Lesions Identify Potential Targets for Therapy Clinical Immunology. 123: S153. DOI: 10.1016/J.Clim.2007.03.075 |
0.631 |
|
| 2006 |
Ho PP, Higgins JP, Kidd BA, Tomooka B, Digennaro C, Lee LY, de Vegvar HE, Steinman L, Robinson WH. Tolerizing DNA vaccines for autoimmune arthritis. Autoimmunity. 39: 675-82. PMID 17178564 DOI: 10.1080/08916930601061603 |
0.317 |
|
| 2006 |
Steinman L. The coming of age for antigen-specific therapy of multiple sclerosis. European Journal of Neurology. 13: 793-4. PMID 16879287 DOI: 10.1111/J.1468-1331.2006.01532.X |
0.318 |
|
| 2006 |
Weber MS, Youssef S, Dunn SE, Prod'homme T, Neuhaus O, Stuve O, Greenwood J, Steinman L, Zamvil SS. Statins in the treatment of central nervous system autoimmune disease. Journal of Neuroimmunology. 178: 140-8. PMID 16860400 DOI: 10.1016/J.Jneuroim.2006.06.006 |
0.4 |
|
| 2006 |
Steinman L, Zamvil SS. How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis. Annals of Neurology. 60: 12-21. PMID 16802293 DOI: 10.1002/Ana.20913 |
0.368 |
|
| 2006 |
Fontoura P, Steinman L. Nogo in multiple sclerosis: growing roles of a growth inhibitor. Journal of the Neurological Sciences. 245: 201-10. PMID 16682057 DOI: 10.1016/J.Jns.2005.07.020 |
0.412 |
|
| 2006 |
Greenwood J, Steinman L, Zamvil SS. Statin therapy and autoimmune disease: from protein prenylation to immunomodulation Nature Reviews Immunology. 6: 358-370. PMID 16639429 DOI: 10.1038/Nri1839 |
0.339 |
|
| 2006 |
Langer-Gould A, Steinman L. Progressive multifocal leukoencephalopathy and multiple sclerosis: lessons from natalizumab. Current Neurology and Neuroscience Reports. 6: 253-8. PMID 16635435 DOI: 10.1007/S11910-006-0013-Z |
0.321 |
|
| 2006 |
Frohman EM, Havrdova E, Lublin F, Barkhof F, Achiron A, Sharief MK, Stuve O, Racke MK, Steinman L, Weiner H, Olek M, Zivadinov R, Corboy J, Raine C, Cutter G, et al. Most patients with multiple sclerosis or a clinically isolated demyelinating syndrome should be treated at the time of diagnosis. Archives of Neurology. 63: 614-9. PMID 16606781 DOI: 10.1001/Archneur.63.4.614 |
0.339 |
|
| 2006 |
Stüve O, Youssef S, Weber MS, Nessler S, von Büdingen HC, Hemmer B, Prod'homme T, Sobel RA, Steinman L, Zamvil SS. Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity. The Journal of Clinical Investigation. 116: 1037-44. PMID 16543951 DOI: 10.1172/Jci25805 |
0.395 |
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| 2006 |
Prod'homme T, Weber MS, Steinman L, Zamvil SS. A neuropeptide in immune-mediated inflammation, Y? Trends in Immunology. 27: 164-167. PMID 16530483 DOI: 10.1016/J.It.2006.02.003 |
0.384 |
|
| 2006 |
Dunn SE, Youssef S, Goldstein MJ, Prod'homme T, Weber MS, Zamvil SS, Steinman L. Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin. The Journal of Experimental Medicine. 203: 401-12. PMID 16476765 DOI: 10.1084/Jem.20051129 |
0.41 |
|
| 2006 |
Steinman L. Controlling autoimmunity in sporadic inclusion-body myositis Neurology. 66. PMID 16432146 DOI: 10.1212/01.Wnl.0000192110.22621.09 |
0.31 |
|
| 2006 |
Musio S, Gallo B, Scabeni S, Lapilla M, Poliani PL, Matarese G, Ohtsu H, Galli SJ, Mantegazza R, Steinman L, Pedotti R. A key regulatory role for histamine in experimental autoimmune encephalomyelitis: disease exacerbation in histidine decarboxylase-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 176: 17-26. PMID 16365391 DOI: 10.4049/Jimmunol.176.1.17 |
0.396 |
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| 2006 |
Kanter JL, Narayana S, Ho PP, Catz I, Warren KG, Sobel RA, Steinman L, Robinson WH. Lipid microarrays identify key mediators of autoimmune brain inflammation. Nature Medicine. 12: 138-43. PMID 16341241 DOI: 10.1038/Nm1344 |
0.4 |
|
| 2006 |
Fontoura P, Garren H, Steinman L. Antigen-specific therapies in multiple sclerosis: going beyond proteins and peptides. International Reviews of Immunology. 24: 415-46. PMID 16318989 DOI: 10.1080/08830180500379655 |
0.432 |
|
| 2006 |
Zeiser R, Youssef S, Baker J, Steinman L, Negrin R. Type II HMG-CoA Reductase Inhibitors (Statins) Provide Acute-Graft-Versus-Host Disease Protection by Th-2 Cytokine Induction While Sparing Graft-Versus-Leukemia Activity. Blood. 108: 189-189. DOI: 10.1182/Blood.V108.11.189.189 |
0.389 |
|
| 2006 |
Platten M, Ho PP, Steinman L. Anti-inflammatory strategies for the treatment of multiple sclerosis - tryptophan catabolites may hold the key Drug Discovery Today: Therapeutic Strategies. 3: 401-408. DOI: 10.1016/J.Ddstr.2006.09.005 |
0.405 |
|
| 2006 |
Dunn S, Ousman S, Sobel R, Zuniga L, Baranzini S, Crowell A, Loh J, Oksenberg J, Steinman L. Sa.18. PPARα Mediates the Sexual Dimorphism in the Development of Th1-Mediated CNS Autoimmune Disease Clinical Immunology. 119: S111. DOI: 10.1016/J.Clim.2006.04.250 |
0.318 |
|
| 2006 |
Platten M, Youssef S, Hur EM, Ho P, Ousman S, Sobel R, Steinman L. Sa.12. Blocking Angiotensin II Suppresses IL-12 Signaling in Autoreactive Th Cells and Treats Autoimmune Neuroinflammation Clinical Immunology. 119: S109. DOI: 10.1016/J.Clim.2006.04.244 |
0.731 |
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| 2006 |
Kanter J, Johnson A, Ho P, Hur EM, Narayana S, Steinman L, Robinson W. OR.67. Microarray Identified Lipids Modulate Autoimmune Demyelinating Disease Clinical Immunology. 119: S29. DOI: 10.1016/J.Clim.2006.04.223 |
0.741 |
|
| 2005 |
Weber MS, Prod'homme T, Steinman L, Zamvil SS. Drug Insight: using statins to treat neuroinflammatory disease. Nature Reviews Neurology. 1: 106-112. PMID 16932506 DOI: 10.1038/Ncpneuro0047 |
0.339 |
|
| 2005 |
Steinman L, Utz PJ, Robinson WH. Suppression of Autoimmunity via Microbial Mimics of Altered Peptide Ligands Current Topics in Microbiology and Immunology. 296: 55-63. PMID 16323420 DOI: 10.1007/3-540-30791-5_4 |
0.336 |
|
| 2005 |
Platten M, Ho PP, Youssef S, Fontoura P, Garren H, Hur EM, Gupta R, Lee LY, Kidd BA, Robinson WH, Sobel RA, Selley ML, Steinman L. Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite. Science (New York, N.Y.). 310: 850-5. PMID 16272121 DOI: 10.1126/Science.1117634 |
0.781 |
|
| 2005 |
Ho PP, Fontoura P, Platten M, Sobel RA, DeVoss JJ, Lee LY, Kidd BA, Tomooka BH, Capers J, Agrawal A, Gupta R, Zernik J, Yee MK, Lee BJ, Garren H, ... ... Steinman L, et al. A suppressive oligodeoxynucleotide enhances the efficacy of myelin cocktail/IL-4-tolerizing DNA vaccination and treats autoimmune disease. Journal of Immunology (Baltimore, Md. : 1950). 175: 6226-34. PMID 16237121 DOI: 10.4049/Jimmunol.175.9.6226 |
0.675 |
|
| 2005 |
Frohman EM, Stüve O, Havrdova E, Corboy J, Achiron A, Zivadinov R, Sorensen PS, Phillips JT, Weinshenker B, Hawker K, Hartung HP, Steinman L, Zamvil S, Cree BA, Hauser S, et al. Therapeutic considerations for disease progression in multiple sclerosis: evidence, experience, and future expectations. Archives of Neurology. 62: 1519-30. PMID 16216934 DOI: 10.1001/Archneur.62.10.1519 |
0.312 |
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| 2005 |
Frohman EM, Filippi M, Stuve O, Waxman SG, Corboy J, Phillips JT, Lucchinetti C, Wilken J, Karandikar N, Hemmer B, Monson N, De Keyser J, Hartung H, Steinman L, Oksenberg JR, et al. Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directions. Archives of Neurology. 62: 1345-56. PMID 16157741 DOI: 10.1001/Archneur.62.9.1345 |
0.387 |
|
| 2005 |
Steinman L, Zamvil SS. Virtues and pitfalls of EAE for the development of therapies for multiple sclerosis Trends in Immunology. 26: 565-571. PMID 16153891 DOI: 10.1016/J.It.2005.08.014 |
0.379 |
|
| 2005 |
Steinman L. Blocking adhesion molecules as therapy for multiple sclerosis: natalizumab Nature Reviews Drug Discovery. 4: 510-518. PMID 15931259 DOI: 10.1038/Nrd1752 |
0.337 |
|
| 2005 |
Feldmann M, Steinman L. Design of effective immunotherapy for human autoimmunity Nature. 435: 612-619. PMID 15931214 DOI: 10.1038/Nature03727 |
0.361 |
|
| 2005 |
Platten M, Steinman L. Multiple sclerosis: trapped in deadly glue. Nature Medicine. 11: 252-3. PMID 15746934 DOI: 10.1038/Nm0305-252 |
0.368 |
|
| 2005 |
Stüve O, Prod'homme T, Slavin A, Youssef S, Dunn S, Steinman L, Zamvil SS. Statins and their potential targets in multiple sclerosis therapy. Expert Opinion On Therapeutic Targets. 7: 613-22. PMID 14498824 DOI: 10.1517/14728222.7.5.613 |
0.322 |
|
| 2005 |
Pedotti R, Steinman L. Histamine in Immune Regulation: Possible Roles in Autoimmune Demyelinating Disease of the Central Nervous System Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents. 4: 637-643. DOI: 10.2174/156801405774933151 |
0.38 |
|
| 2004 |
Fontoura P, Ho PP, DeVoss J, Zheng B, Lee BJ, Kidd BA, Garren H, Sobel RA, Robinson WH, Tessier-Lavigne M, Steinman L. Immunity to the extracellular domain of Nogo-A modulates experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 173: 6981-92. PMID 15557195 DOI: 10.4049/Jimmunol.173.11.6981 |
0.695 |
|
| 2004 |
Graham KL, Robinson WH, Steinman L, Utz PJ. High-throughput methods for measuring autoantibodies in systemic lupus erythematosus and other autoimmune diseases. Autoimmunity. 37: 269-72. PMID 15518040 DOI: 10.1080/08916930410001710686 |
0.325 |
|
| 2004 |
Karpuj M, Steinman L. The multifaceted role of transglutaminase in neurodegeneration: review article. Amino Acids. 26: 373-379. PMID 15290343 DOI: 10.1007/S00726-004-0082-8 |
0.304 |
|
| 2004 |
Steinman L. Immune therapy for autoimmune diseases. Science. 305: 212-216. PMID 15247472 DOI: 10.1126/Science.1099896 |
0.413 |
|
| 2004 |
Steinman L. Elaborate interactions between the immune and nervous systems. Nature Immunology. 5: 575-581. PMID 15164017 DOI: 10.1038/Ni1078 |
0.324 |
|
| 2004 |
Stüve O, Prod'homme T, Youssef S, Dunn S, Neuhaus O, Weber M, Hartung HP, Steinman L, Zamvil SS. Statins as potential therapeutic agents in multiple sclerosis. Current Neurology and Neuroscience Reports. 4: 237-244. PMID 15102350 DOI: 10.1007/S11910-004-0044-2 |
0.312 |
|
| 2003 |
Robinson WH, Utz PJ, Steinman L. Genomic and proteomic analysis of multiple sclerosis. Opinion. Current Opinion in Immunology. 15: 660-7. PMID 14630200 DOI: 10.1016/J.Coi.2003.09.015 |
0.382 |
|
| 2003 |
Stüve O, Youssef S, Dunn S, Slavin AJ, Steinman L, Zamvil SS. The potential therapeutic role of statins in central nervous system autoimmune disorders Cellular and Molecular Life Sciences. 60: 2483-2491. PMID 14625690 DOI: 10.1007/S00018-003-3146-0 |
0.329 |
|
| 2003 |
Robinson WH, Steinman L, Utz PJ. Protein arrays for autoantibody profiling and fine-specificity mapping. Proteomics. 3: 2077-84. PMID 14595805 DOI: 10.1002/Pmic.200300583 |
0.305 |
|
| 2003 |
Ho PP, Fontoura P, Ruiz PJ, Steinman L, Garren H. An immunomodulatory GpG oligonucleotide for the treatment of autoimmunity via the innate and adaptive immune systems. Journal of Immunology (Baltimore, Md. : 1950). 171: 4920-6. PMID 14568974 DOI: 10.4049/Jimmunol.171.9.4920 |
0.42 |
|
| 2003 |
Pedotti R, De Voss JJ, Steinman L, Galli SJ. Involvement of both 'allergic' and 'autoimmune' mechanisms in EAE, MS and other autoimmune diseases. Trends in Immunology. 24: 479-84. PMID 12967671 DOI: 10.1016/S1471-4906(03)00233-3 |
0.428 |
|
| 2003 |
Robinson WH, Fontoura P, Lee BJ, de Vegvar HE, Tom J, Pedotti R, DiGennaro CD, Mitchell DJ, Fong D, Ho PP, Ruiz PJ, Maverakis E, Stevens DB, Bernard CC, Martin R, ... ... Steinman L, et al. Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis. Nature Biotechnology. 21: 1033-9. PMID 12910246 DOI: 10.1038/Nbt859 |
0.378 |
|
| 2003 |
Zamvil SS, Steinman L. Diverse Targets for Intervention during Inflammatory and Neurodegenerative Phases of Multiple Sclerosis Neuron. 38: 685-688. PMID 12797954 DOI: 10.1016/S0896-6273(03)00326-X |
0.401 |
|
| 2003 |
Steinman L, Zamvil S. Transcriptional analysis of targets in multiple sclerosis. Nature Reviews Immunology. 3: 483-492. PMID 12776208 DOI: 10.1038/Nri1108 |
0.339 |
|
| 2003 |
Caillier S, Barcellos LF, Baranzini SE, Swerdlin A, Lincoln RR, Steinman L, Martin E, Haines JL, Pericak-Vance M, Hauser SL, Oksenberg JR. Osteopontin polymorphisms and disease course in multiple sclerosis. Genes and Immunity. 4: 312-5. PMID 12761568 DOI: 10.1038/Sj.Gene.6363952 |
0.374 |
|
| 2003 |
Pedotti R, Sanna M, Tsai M, DeVoss J, Steinman L, McDevitt H, Galli SJ. Severe anaphylactic reactions to glutamic acid decarboxylase (GAD) self peptides in NOD mice that spontaneously develop autoimmune type 1 diabetes mellitus Bmc Immunology [Electronic Resource]. 4: 2. PMID 12597780 DOI: 10.1186/1471-2172-4-2 |
0.679 |
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| 2003 |
Pedotti R, DeVoss JJ, Youssef S, Mitchell D, Wedemeyer J, Madanat R, Garren H, Fontoura P, Tsai M, Galli SJ, Sobel RA, Steinman L. Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination. Proceedings of the National Academy of Sciences of the United States of America. 100: 1867-72. PMID 12576552 DOI: 10.1073/Pnas.252777399 |
0.7 |
|
| 2003 |
Stüve O, Prod'homme T, Slavin A, Youssef S, Dunn S, Steinman L, Zamvil SS. Statins and their potential targets in multiple sclerosis therapy. Expert Opinion On Therapeutic Targets. 7: 613-622. DOI: 10.1517/Eott.7.5.613.22523 |
0.446 |
|
| 2003 |
Steinman L. Response to Comment on "The Influence of the Proinflammatory Cytokine, Osteopontin, on Autoimmune Demyelinating Disease" Science. 299: 1845b-1845. DOI: 10.1126/Science.1080223 |
0.306 |
|
| 2003 |
Stüve O, Youssef S, Steinman L, Zamvil SS. Statins as potential therapeutic agents in neuroinflammatory disorders Current Opinion in Neurology. 16: 393-401. DOI: 10.1097/00019052-200306000-00021 |
0.416 |
|
| 2002 |
Stüve O, Cree BC, von Büdingen HC, Yousef S, Bowen JD, Genain CP, Hauser SL, Steinman L, Zamvil SS. Approved and future pharmacotherapy for multiple sclerosis. The Neurologist. 8: 290-301. PMID 12803676 DOI: 10.1097/00127893-200209000-00002 |
0.358 |
|
| 2002 |
Youssef S, Stüve O, Patarroyo JC, Ruiz PJ, Radosevich JL, Hur EM, Bravo M, Mitchell DJ, Sobel RA, Steinman L, Zamvil SS. The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease. Nature. 420: 78-84. PMID 12422218 DOI: 10.1038/Nature01158 |
0.775 |
|
| 2002 |
Zamvil SS, Steinman L. Cholesterol-lowering statins possess anti-inflammatory activity that might be useful for treatment of MS Neurology. 59: 970-971. PMID 12370448 DOI: 10.1212/Wnl.59.7.970 |
0.371 |
|
| 2002 |
Hueber W, Utz PJ, Steinman L, Robinson WH. Autoantibody profiling for the study and treatment of autoimmune disease. Arthritis Research. 4: 290-5. PMID 12223102 DOI: 10.1186/Ar426 |
0.369 |
|
| 2002 |
Langer-Gould A, Garren H, Slansky A, Ruiz PJ, Steinman L. Late pregnancy suppresses relapses in experimental autoimmune encephalomyelitis: evidence for a suppressive pregnancy-related serum factor. Journal of Immunology (Baltimore, Md. : 1950). 169: 1084-91. PMID 12097417 DOI: 10.4049/Jimmunol.169.2.1084 |
0.355 |
|
| 2002 |
Conlon P, Steinman L. Altered peptide ligands and MS treatment. Science. 296: 1801-1802. PMID 12053936 DOI: 10.1126/Science.296.5574.1801C |
0.34 |
|
| 2002 |
Steinman L, Martin R, Bernard C, Conlon P, Oksenberg JR. Multiple sclerosis: deeper understanding of its pathogenesis reveals new targets for therapy. Annual Review of Neuroscience. 25: 491-505. PMID 12052918 DOI: 10.1146/Annurev.Neuro.25.112701.142913 |
0.323 |
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| 2002 |
Robinson WH, Garren H, Utz PJ, Steinman L. Millennium Award. Proteomics for the development of DNA tolerizing vaccines to treat autoimmune disease. Clinical Immunology (Orlando, Fla.). 103: 7-12. PMID 11987980 DOI: 10.1006/Clim.2002.5185 |
0.381 |
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| 2002 |
Lock C, Hermans G, Pedotti R, Brendolan A, Schadt E, Garren H, Langer-Gould A, Strober S, Cannella B, Allard J, Klonowski P, Austin A, Lad N, Kaminski N, Galli SJ, ... ... Steinman L, et al. Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nature Medicine. 8: 500-8. PMID 11984595 DOI: 10.1038/Nm0502-500 |
0.364 |
|
| 2002 |
Robinson WH, Steinman L, Utz PJ. Proteomics technologies for the study of autoimmune disease. Arthritis and Rheumatism. 46: 885-93. PMID 11953963 DOI: 10.1002/Art.10129 |
0.341 |
|
| 2002 |
Robinson WH, DiGennaro C, Hueber W, Haab BB, Kamachi M, Dean EJ, Fournel S, Fong D, Genovese MC, de Vegvar HE, Skriner K, Hirschberg DL, Morris RI, Muller S, Pruijn GJ, ... ... Steinman L, et al. Autoantigen microarrays for multiplex characterization of autoantibody responses. Nature Medicine. 8: 295-301. PMID 11875502 DOI: 10.1038/Nm0302-295 |
0.33 |
|
| 2002 |
Karpuj MV, Becher MW, Springer JE, Chabas D, Youssef S, Pedotti R, Mitchell D, Steinman L. Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine. Nature Medicine. 8: 143-9. PMID 11821898 DOI: 10.1038/Nm0202-143 |
0.31 |
|
| 2002 |
Karpuj MV, Becher MW, Steinman L. Evidence for a role for transglutaminase in Huntington's disease and the potential therapeutic implications. Neurochemistry International. 40: 31-6. PMID 11738470 DOI: 10.1016/S0197-0186(01)00060-2 |
0.311 |
|
| 2002 |
Robinson WH, Steinman L, Utz PJ. Protein and Peptide Array Analysis of Autoimmune Disease Biotechniques. 33: S66-S69. DOI: 10.2144/Dec02-Robinson |
0.301 |
|
| 2002 |
Robinson W, Huber W, Venrooij Wv, Muller S, Panayi G, Verweij C, Smolen J, Steinman L, Utz P. Protein microarray characterization of autoantibody responses in rheumatoid arthritis and systemic lupus erythematosus Arthritis Research & Therapy. 4: 76-76. DOI: 10.1186/Ar521 |
0.322 |
|
| 2001 |
Steinman L. Blockade of gamma interferon might be beneficial in MS. Multiple Sclerosis Journal. 7: 275-276. PMID 11724441 DOI: 10.1177/135245850100700501 |
0.33 |
|
| 2001 |
Chabas D, Baranzini SE, Mitchell D, Bernard CC, Rittling SR, Denhardt DT, Sobel RA, Lock C, Karpuj M, Pedotti R, Heller R, Oksenberg JR, Steinman L. The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science (New York, N.Y.). 294: 1731-5. PMID 11721059 DOI: 10.1126/Science.1062960 |
0.447 |
|
| 2001 |
Steinman L. Immunotherapy of multiple sclerosis: the end of the beginning. Current Opinion in Immunology. 13: 597-600. PMID 11544011 DOI: 10.1016/S0952-7915(00)00266-1 |
0.351 |
|
| 2001 |
Steinman L. Myelin-specific CD8 T cells in the pathogenesis of experimental allergic encephalitis and multiple sclerosis Journal of Experimental Medicine. 194. PMID 11535639 DOI: 10.1084/Jem.194.5.F27 |
0.416 |
|
| 2001 |
Steinman L. Multiple sclerosis: a two-stage disease Nature Immunology. 2: 762-764. PMID 11526378 DOI: 10.1038/Ni0901-762 |
0.339 |
|
| 2001 |
Hauben E, Agranov E, Gothilf A, Nevo U, Cohen A, Smirnov I, Steinman L, Schwartz M. Posttraumatic therapeutic vaccination with modified myelin self-antigen prevents complete paralysis while avoiding autoimmune disease. The Journal of Clinical Investigation. 108: 591-9. PMID 11518733 DOI: 10.1172/Jci12837 |
0.335 |
|
| 2001 |
Ruiz PJ, DeVoss JJ, Nguyen LV, Fontoura PP, Hirschberg DL, Mitchell DJ, Garcia KC, Steinman L. Immunomodulation of experimental autoimmune encephalomyelitis with ordered peptides based on MHC-TCR binding motifs. Journal of Immunology (Baltimore, Md. : 1950). 167: 2688-93. PMID 11509612 DOI: 10.4049/Jimmunol.167.5.2688 |
0.704 |
|
| 2001 |
Steinman L. Multiple sclerosis and gene expression profiling. Advances in Experimental Medicine and Biology. 490: 109-112. PMID 11505968 DOI: 10.1007/978-1-4615-1243-1_11 |
0.335 |
|
| 2001 |
Garren H, Ruiz PJ, Watkins TA, Fontoura P, Nguyen LT, Estline ER, Hirschberg DL, Steinman L. Combination of gene delivery and DNA vaccination to protect from and reverse Th1 autoimmune disease via deviation to the Th2 pathway. Immunity. 15: 15-22. PMID 11485734 DOI: 10.1016/S1074-7613(01)00171-6 |
0.323 |
|
| 2001 |
Urbanek-Ruiz I, Ruiz PJ, Paragas V, Garren H, Steinman L, Fathman CG. Immunization with DNA encoding an immunodominant peptide of insulin prevents diabetes in NOD mice. Clinical Immunology (Orlando, Fla.). 100: 164-71. PMID 11465945 DOI: 10.1006/Clim.2001.5055 |
0.318 |
|
| 2001 |
Steinman L, Conlon P. Antigen Specific Immunotherapy of Multiple Sclerosis Journal of Clinical Immunology. 21: 93-98. PMID 11332658 DOI: 10.1023/A:1011020225433 |
0.421 |
|
| 2001 |
Pedotti R, Mitchell D, Wedemeyer J, Karpuj M, Chabas D, Hattab EM, Tsai M, Galli SJ, Steinman L. An unexpected version of horror autotoxicus: anaphylactic shock to a self-peptide. Nature Immunology. 2: 216-22. PMID 11224520 DOI: 10.1038/85266 |
0.334 |
|
| 2001 |
Robinson W, DiGennaro C, Hueber W, Fong D, Haab B, Hirshberg D, Muller S, Pruijn G, Venrooij Wv, Smolen J, Brown P, Steinman L, Utz PJ. Protein microarray characterization of the autoantibody response in systemic lupus erythematosus and related diseases Arthritis Research & Therapy. 3: 1-1. DOI: 10.1186/Ar152 |
0.347 |
|
| 2000 |
Kappos L, Comi G, Panitch H, Oger J, Antel J, Conlon P, Steinman L. Induction of a non-encephalitogenic type 2 T helper-cell autoimmune response in multiple sclerosis after administration of an altered peptide ligand in a placebo-controlled, randomized phase II trial. The Altered Peptide Ligand in Relapsing MS Study Group. Nature Medicine. 6: 1176-82. PMID 11017151 DOI: 10.1038/80525 |
0.342 |
|
| 2000 |
Steinman L. Despite epitope spreading in the pathogenesis of autoimmune disease, highly restricted approaches to immune therapy may still succeed [with a hedge on this bet]. Journal of Autoimmunity. 14: 278-282. PMID 10882053 DOI: 10.1006/Jaut.2000.0379 |
0.352 |
|
| 2000 |
Karpuj MV, Steinman L, Oksenberg JR. Multiple sclerosis: a polygenic disease involving epistatic interactions, germline rearrangements and environmental effects. Neurogenetics. 1: 21-8. PMID 10735270 DOI: 10.1007/S100480050003 |
0.373 |
|
| 2000 |
Steinman L. Multiple approaches to multiple sclerosis. Nature Medicine. 6: 15-16. PMID 10613811 DOI: 10.1038/71466 |
0.356 |
|
| 2000 |
Lock C, Oksenberg J, Steinman L. The role of TNFalpha and lymphotoxin in demyelinating disease. Annals of the Rheumatic Diseases. I121-8. PMID 10577988 DOI: 10.1136/Ard.58.2008.I121 |
0.404 |
|
| 1999 |
Steinman L. Assessment of animal models for MS and demyelinating disease in the design of rational therapy. Neuron. 24: 511-514. PMID 10595504 DOI: 10.1016/S0896-6273(00)81107-1 |
0.343 |
|
| 1999 |
Panzara MA, Gussoni E, Begovich AB, Murray RS, Zang YQ, Appel SH, Steinman L, Zhang J. T cell receptor BV gene rearrangements in the spinal cords and cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Neurobiology of Disease. 6: 392-405. PMID 10527806 DOI: 10.1006/Nbdi.1999.0252 |
0.35 |
|
| 1999 |
Conlon P, Oksenberg JR, Zhang J, Steinman L. The immunobiology of multiple sclerosis: an autoimmune disease of the central nervous system. Neurobiology of Disease. 6: 149-166. PMID 10408805 DOI: 10.1006/Nbdi.1999.0239 |
0.399 |
|
| 1999 |
Brocke S, Piercy C, Steinman L, Weissman IL, Veromaa T. Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment. Proceedings of the National Academy of Sciences of the United States of America. 96: 6896-901. PMID 10359810 DOI: 10.1073/Pnas.96.12.6896 |
0.385 |
|
| 1999 |
Ruiz PJ, Garren H, Hirschberg DL, Langer-Gould AM, Levite M, Karpuj MV, Southwood S, Sette A, Conlon P, Steinman L. Microbial epitopes act as altered peptide ligands to prevent experimental autoimmune encephalomyelitis Journal of Experimental Medicine. 189: 1275-1283. PMID 10209044 DOI: 10.1084/Jem.189.8.1275 |
0.337 |
|
| 1999 |
Steinman L. Absence of "original antigenic sin" in autoimmunity provides an unforeseen platform for immune therapy. Journal of Experimental Medicine. 189: 1021-1024. PMID 10190892 DOI: 10.1084/Jem.189.7.1021 |
0.414 |
|
| 1999 |
Falta MT, Magin GK, Allegretta M, Steinman L, Atkinson MA, Brostoff SW, Albertini RJ. Selection of hprt mutant T cells as surrogates for dividing cells reveals a restricted T cell receptor BV repertoire in insulin-dependent diabetes mellitus Clinical Immunology. 90: 340-351. PMID 10075863 DOI: 10.1006/Clim.1998.4664 |
0.323 |
|
| 1999 |
Boccaccio GL, Mor F, Steinman L. Non-coding plasmid DNA induces IFN-gamma in vivo and suppresses autoimmune encephalomyelitis. International Immunology. 11: 289-96. PMID 10069427 DOI: 10.1093/Intimm/11.2.289 |
0.331 |
|
| 1999 |
Dal Canto RA, Shaw MK, Nolan GP, Steinman L, Fathman CG. Local delivery of TNF by retrovirus-transduced T lymphocytes exacerbates experimental autoimmune encephalomyelitis. Clinical Immunology (Orlando, Fla.). 90: 10-4. PMID 9884347 DOI: 10.1006/Clim.1998.4653 |
0.428 |
|
| 1998 |
Garren H, Steinman L, Lock C. The specificity of the antibody response in multiple sclerosis. Annals of Neurology. 43: 4-6. PMID 9450762 DOI: 10.1002/Ana.410430105 |
0.332 |
|
| 1997 |
Hvas J, McLEAN C, Justesen J, Kannourakis G, Steinman L, Oksenberg JR, Bernard CCA. Perivascular T Cells Express the Pro-Inflammatory Chemokine RANTES mRNA in Multiple Sclerosis Lesions Scandinavian Journal of Immunology. 46: 195-203. PMID 9584001 DOI: 10.1046/J.1365-3083.1997.D01-100.X |
0.357 |
|
| 1997 |
O'Garra A, Steinman L, Gijbels K. CD4+ T-cell subsets in autoimmunity. Current Opinion in Immunology. 9: 872-883. PMID 9492992 DOI: 10.1016/S0952-7915(97)80192-6 |
0.4 |
|
| 1997 |
Steinman L, Oldstone MB. More mayhem from molecular mimics. Nature Medicine. 3: 1321-2. PMID 9396597 DOI: 10.1038/Nm1297-1321 |
0.337 |
|
| 1997 |
Steinman L, Conlon P. Viral damage and the breakdown of self-tolerance. Nature Medicine. 3: 1085-1087. PMID 9334717 DOI: 10.1038/Nm1097-1085 |
0.342 |
|
| 1997 |
Wucherpfennig KW, Catz I, Hausmann S, Strominger JL, Steinman L, Warren KG. Recognition of the immunodominant myelin basic protein peptide by autoantibodies and HLA-DR2-restricted T cell clones from multiple sclerosis patients. Identity of key contact residues in the B-cell and T-cell epitopes. The Journal of Clinical Investigation. 100: 1114-22. PMID 9276728 DOI: 10.1172/Jci119622 |
0.403 |
|
| 1997 |
Steinman L. Some Misconceptions about Understanding Autoimmunity through Experiments with Knockouts Journal of Experimental Medicine. 185: 2039-2041. PMID 9221283 DOI: 10.1084/Jem.185.12.2039 |
0.396 |
|
| 1997 |
Liblau R, Steinman L, Brocke S. Experimental autoimmune encephalomyelitis in IL-4-deficient mice. International Immunology. 9: 799-803. PMID 9184926 DOI: 10.1093/Intimm/9.5.799 |
0.355 |
|
| 1997 |
Shaw MK, Lorens JB, Dhawan A, DalCanto R, Tse HY, Tran AB, Bonpane C, Eswaran SL, Brocke S, Sarvetnick N, Steinman L, Nolan GP, Fathman CG. Local delivery of interleukin 4 by retrovirus-transduced T lymphocytes ameliorates experimental autoimmune encephalomyelitis. The Journal of Experimental Medicine. 185: 1711-4. PMID 9151908 DOI: 10.1084/Jem.185.9.1711 |
0.457 |
|
| 1997 |
Gaur A, Boehme SA, Chalmers D, Crowe PD, Pahuja A, Ling N, Brocke S, Steinman L, Conlon PJ. Amelioration of relapsing experimental autoimmune encephalomyelitis with altered myelin basic protein peptides involves different cellular mechanisms. Journal of Neuroimmunology. 74: 149-58. PMID 9119968 DOI: 10.1016/S0165-5728(96)00220-2 |
0.394 |
|
| 1997 |
Brocke S, Piercy C, Steinman L. Superantigens in demyelinating disease. Springer Seminars in Immunopathology. 18: 51-6. PMID 8984679 DOI: 10.1007/Bf00792608 |
0.411 |
|
| 1997 |
Hafler DA, Saadeh MG, Kuchroo VK, Milford E, Steinman L. TCR usage in human and experimental demyelinating disease. Immunology Today. 17: 152-9. PMID 8871344 DOI: 10.1016/0167-5699(96)80611-6 |
0.406 |
|
| 1996 |
Vergelli M, Hemmer B, Utz U, Vogt A, Kalbus M, Tranquill L, Conlon P, Ling N, Steinman L, McFarland HF, Martin R. Differential activation of human autoreactive T cell clones by altered peptide ligands derived from myelin basic protein peptide (87-99) European Journal of Immunology. 26: 2624-2634. PMID 8921948 DOI: 10.1002/Eji.1830261113 |
0.409 |
|
| 1996 |
Boccaccio GL, Steinman L. Multiple sclerosis: from a myelin point of view. Journal of Neuroscience Research. 45: 647-54. PMID 8892076 DOI: 10.1002/(Sici)1097-4547(19960915)45:6<647::Aid-Jnr1>3.0.Co;2-8 |
0.416 |
|
| 1996 |
Shanafelt MC, Yssel H, Soderberg C, Steinman L, Adelman DC, Peltz G, Lahesmaa R. CD45 isoforms on human CD4+ T-cell subsets. The Journal of Allergy and Clinical Immunology. 98: 433-40. PMID 8757221 DOI: 10.1016/S0091-6749(96)70168-9 |
0.345 |
|
| 1996 |
Waisman A, Ruiz PJ, Hirschberg DL, Gelman A, Oksenberg JR, Brocke S, Mor F, Cohen IR, Steinman L. Suppressive vaccination with DNA encoding a variable region gene of the T-cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity. Nature Medicine. 2: 899-905. PMID 8705860 DOI: 10.1038/Nm0896-899 |
0.42 |
|
| 1996 |
Oro AS, Guarino TJ, Driver R, Steinman L, Umetsu DT. Regulation of disease susceptibility: Decreased prevalence of IgE-mediated allergic disease in patients with multiple sclerosis The Journal of Allergy and Clinical Immunology. 97: 1402-1408. PMID 8648038 DOI: 10.1016/S0091-6749(96)70210-5 |
0.438 |
|
| 1996 |
Steinman L. A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: a tale of smart bombs and the infantry Proceedings of the National Academy of Sciences of the United States of America. 93: 2253-2256. PMID 8637858 DOI: 10.1073/Pnas.93.6.2253 |
0.384 |
|
| 1996 |
Brocke S, Quigley L, McFarland HF, Steinman L. Isolation and characterization of autoreactive T cells in experimental autoimmune encephalomyelitis of the mouse Methods: a Companion to Methods in Enzymology. 9: 458-462. DOI: 10.1006/Meth.1996.0053 |
0.385 |
|
| 1995 |
Steinman L, Waisman A, Altmann D. Major T-cell responses in multiple sclerosis. Molecular Medicine Today. 1: 79-83. PMID 17607899 DOI: 10.1016/S1357-4310(95)92366-7 |
0.439 |
|
| 1995 |
Steinman L. Escape from “horror autotoxicus”: Pathogenesis and treatment of autoimmune disease Cell. 80: 7-10. PMID 7813019 DOI: 10.1016/0092-8674(95)90443-3 |
0.317 |
|
| 1995 |
Szafer F, Price VH, Oksenberg JR, Steinman L. T-cell receptor repertoire Vβ in alopecia areata Journal of Investigative Dermatology. 104. PMID 7738379 DOI: 10.1038/Jid.1995.43 |
0.315 |
|
| 1995 |
Lahesmaa R, Soderberg C, Bliska J, Allsup A, Luukkainen R, Steinman L, Uchiyama T, Peltz G. Pathogen antigen- and superantigen-reactive synovial fluid t cells in reactive arthritis Journal of Infectious Diseases. 172: 1290-1297. PMID 7594666 DOI: 10.1093/Infdis/172.5.1290 |
0.391 |
|
| 1995 |
Allegretta M, Steinman L. Unique T-cell receptor junctional sequences found in multiple sclerosis and T-cells mediating experimental allergic encephalomyelitis. Annals of the New York Academy of Sciences. 756: 265-82. PMID 7544077 DOI: 10.1111/J.1749-6632.1995.Tb44524.X |
0.425 |
|
| 1995 |
Steinman L. Multiple sclerosis. Presenting an odd autoantigen. Nature. 375: 739-40. PMID 7541112 DOI: 10.1038/375739B0 |
0.359 |
|
| 1995 |
Lindsey JW, Pappolla M, Steinman L. Reinduction of Experimental Autoimmune Encephalomyelitis in Mice Cellular Immunology. 162: 235-240. PMID 7538049 DOI: 10.1006/Cimm.1995.1074 |
0.323 |
|
| 1995 |
Warren KG, Catz I, Steinman L. Fine specificity of the antibody response to myelin basic protein in the central nervous system in multiple sclerosis: the minimal B-cell epitope and a model of its features. Proceedings of the National Academy of Sciences of the United States of America. 92: 11061-5. PMID 7479937 DOI: 10.1073/Pnas.92.24.11061 |
0.37 |
|
| 1995 |
Vollmer TL, Gaiser C, Dell'oca RL, Porteus M, Steinman L, Stevens DA. Coccidioidal antigen reactive CD4+ T-lymphocytes in the cerebrospinal fluid in Coccidioides immitis meningitis Medical Mycology. 33: 43-48. DOI: 10.1080/02681219580000091 |
0.349 |
|
| 1994 |
Steinman L, Miller A, Bernard CCA, Oksenberg JR. The Epigenetics of Multiple Sclerosis: Clues to Etiology and a Rationale for Immune Therapy Annual Review of Neuroscience. 17: 247-265. PMID 8210175 DOI: 10.1146/Annurev.Ne.17.030194.001335 |
0.448 |
|
| 1994 |
Brocke S, Veromaa T, Weissman IL, Gijbels K, Steinman L. Infection and multiple sclerosis: a possible role for superantigens? Trends in Microbiology. 2: 250-4. PMID 8081652 DOI: 10.1016/0966-842X(94)90630-0 |
0.409 |
|
| 1994 |
Lindsey JW, Hodgkinson S, Mehta R, Mitchell D, Enzmann D, Steinman L. Repeated treatment with chimeric anti-CD4 antibody in multiple sclerosis. Annals of Neurology. 36: 183-9. PMID 8053654 DOI: 10.1002/Ana.410360210 |
0.322 |
|
| 1994 |
Allegretta M, Albertini RJ, Howell MD, Smith LR, Martin R, McFarland HF, Sriram S, Brostoff S, Steinman L. Homologies between T cell receptor junctional sequences unique to multiple sclerosis and T cells mediating experimental allergic encephalomyelitis Journal of Clinical Investigation. 94: 105-109. PMID 8040252 DOI: 10.1172/Jci117295 |
0.425 |
|
| 1994 |
Gijbels K, Galardy RE, Steinman L. Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases. Journal of Clinical Investigation. 94: 2177-2182. PMID 7989572 DOI: 10.1172/Jci117578 |
0.342 |
|
| 1994 |
Lahesmaa R, Shanafelt M, Steinman L, Peltz G. Immunopathogenesis of human inflammatory arthritis: lessons from Lyme and reactive arthritis. The Journal of Infectious Diseases. 170: 978-985. PMID 7930744 DOI: 10.1093/Infdis/170.4.978 |
0.327 |
|
| 1994 |
Cunha-Neto E, Moliterno R, Coelho V, Guilherme L, Bocchi E, Higuchi Mde L, Stolf N, Pileggi F, Steinman L, Kalil J. Restricted heterogeneity of T cell receptor variable alpha chain transcripts in hearts of Chagas' disease cardiomyopathy patients. Parasite Immunology. 16: 171-9. PMID 7914690 DOI: 10.1111/J.1365-3024.1994.Tb00337.X |
0.303 |
|
| 1994 |
Yang XD, Michie SA, Tisch R, Karin N, Steinman L, McDevitt HO. Cell Adhesion Molecules: A Selective Therapeutic Target for Alleviation of IDDM Journal of Autoimmunity. 7: 859-864. PMID 7534080 DOI: 10.1006/Jaut.1994.1069 |
0.317 |
|
| 1994 |
Lodge PA, Allegretta M, Steinman L, Sriram S. Myelin basic protein peptide specificity and T-cell receptor gene usage of HPRT mutant T-cell clones in patients with multiple sclerosis. Annals of Neurology. 36: 734-40. PMID 7526775 DOI: 10.1002/Ana.410360508 |
0.393 |
|
| 1994 |
Karin N, Mitchell DJ, Brocke S, Ling N, Steinman L. Reversal of experimental autoimmune encephalomyelitis by a soluble peptide variant of a myelin basic protein epitope: T cell receptor antagonism and reduction of interferon gamma and tumor necrosis factor alpha production. The Journal of Experimental Medicine. 180: 2227-37. PMID 7525850 DOI: 10.1084/Jem.180.6.2227 |
0.381 |
|
| 1994 |
Zamvil SS, al-Sabbagh A, Nelson PA, Kaul D, Charles MS, Mitchell DJ, Steinman L, Weiner HL, Kuchroo VK. 'Lupus-prone' mice are susceptible to organ-specific autoimmune disease, experimental allergic encephalomyelitis. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 62: 113-9. PMID 7524528 DOI: 10.1159/000163887 |
0.4 |
|
| 1994 |
Gautam AM, Lock CB, Smilek DE, Pearson CI, Steinman L, McDevitt HO. Minimum structural requirements for peptide presentation by major histocompatibility complex class II molecules: implications in induction of autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 91: 767-71. PMID 7507253 DOI: 10.1073/Pnas.91.2.767 |
0.384 |
|
| 1993 |
Kan-Mitchell J, Huang XQ, Steinman L, Oksenberg JR, Harel W, Parker JW, Goedegebuure PS, Darrow TL, Mitchell MS. Clonal analysis of in vivo activated CD8+ cytotoxic T lymphocytes from a melanoma patient responsive to active specific immunotherapy. Cancer Immunology, Immunotherapy : Cii. 37: 15-25. PMID 8513449 DOI: 10.1007/Bf01516937 |
0.353 |
|
| 1993 |
Hvas J, Oksenberg JR, Fernando R, Steinman L, Bernard CCA. γδ T cell receptor repertoire in brain lesions of patients with multiple sclerosis Journal of Neuroimmunology. 46: 225-234. PMID 8395544 DOI: 10.1016/0165-5728(93)90253-U |
0.422 |
|
| 1993 |
Steinman L. Connections between the immune system and the nervous system Proceedings of the National Academy of Sciences of the United States of America. 90: 7912-7914. PMID 8367442 DOI: 10.1073/Pnas.90.17.7912 |
0.387 |
|
| 1993 |
Steinman L. Therapeutic peptides that block interaction of T cells with MHC in experimental allergic encephalomyelitis. Annals of the New York Academy of Sciences. 685: 521-524. PMID 8363260 DOI: 10.1111/J.1749-6632.1993.Tb35914.X |
0.336 |
|
| 1993 |
Melms A, Oksenberg JR, Malcherek G, Schoepfer R, Müller CA, Lindstrom J, Steinman L. T-cell receptor gene usage of acetylcholine receptor-specific T-helper cells. Annals of the New York Academy of Sciences. 681: 313-4. PMID 8357179 DOI: 10.1111/J.1749-6632.1993.Tb22904.X |
0.318 |
|
| 1993 |
Oksenberg JR, Panzara MA, Steinman L. Multiple sclerosis: From immunogenetics to immunotherapy Journal of the Neurological Sciences. 115. PMID 8340790 DOI: 10.1016/0022-510X(93)90206-E |
0.378 |
|
| 1993 |
Struyk L, Kurnick JT, Hawes GE, Laar JMv, Schipper R, Oksenberg JR, Steinman L, Vries RPd, Breedveld FC, Elsen Pvd. T-cell receptor V-gene usage in synovial fluid lymphocytes of patients with chronic arthritis. Human Immunology. 37: 237-251. PMID 8300409 DOI: 10.1016/0198-8859(93)90507-W |
0.3 |
|
| 1993 |
Brocke S, Gaur A, Piercy C, Gautam A, Gijbels K, Fathman CG, Steinman L. Induction of relapsing paralysis in experimental autoimmune encephalomyelitis by bacterial superantigen Nature. 365: 642-644. PMID 7692305 DOI: 10.1038/365642A0 |
0.449 |
|
| 1993 |
Wilson DB, Steinman L, Gold DP. The V-region disease hypothesis: new evidence suggests it is probably wrong. Immunology Today. 14: 376-80; discussion 3. PMID 7691066 DOI: 10.1016/0167-5699(93)90136-9 |
0.365 |
|
| 1992 |
Oksenberg JR, Steinman L. New approaches to the therapy of demyelinating disease. Current Opinion in Neurobiology. 1: 436-40. PMID 1821688 DOI: 10.1016/0959-4388(91)90066-G |
0.372 |
|
| 1992 |
Panzara MA, Oksenberg JR, Steinman L. The polymerase chain reaction for detection of T-cell antigen receptor expression. Current Opinion in Immunology. 4: 205-10. PMID 1605910 DOI: 10.1016/0952-7915(92)90015-7 |
0.343 |
|
| 1992 |
Yednock TA, Cannon C, Fritz LC, Sanchez-Madrid F, Steinman L, Karin N. Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. Nature. 356: 63-66. PMID 1538783 DOI: 10.1038/356063A0 |
0.375 |
|
| 1992 |
Rao NA, Atalla L, Fong S, Chen F, Linker-Israeli M, Steinman L. Antigen-Specific Suppressor Cells in Experimental Autoimmune Uveitis Ophthalmic Research. 24: 92-98. PMID 1535119 DOI: 10.1159/000267152 |
0.332 |
|
| 1992 |
Steinman L, Oksenberg JR, Bernard CCA. Association of susceptibility to multiple sclerosis with TCR genes. Immunology Today. 13: 49-51. PMID 1533525 DOI: 10.1016/0167-5699(92)90133-R |
0.407 |
|
| 1992 |
Bucht A, Oksenberg JR, Lindblad S, Grönberg A, Steinman L, Klareskog L. Characterization of T‐Cell Receptor αβ Repertoire in Synovial Tissue from Different Temporal Phases of Rheumatoid Arthritis Scandinavian Journal of Immunology. 35: 159-165. PMID 1531390 DOI: 10.1111/J.1365-3083.1992.Tb02846.X |
0.309 |
|
| 1992 |
Steinman L. Multiple sclerosis and its animal models: the role of the major histocompatibility complex and the T cell receptor repertoire. Springer Seminars in Immunopathology. 14: 79-93. PMID 1440199 DOI: 10.1007/Bf00197133 |
0.375 |
|
| 1992 |
Lindsey JW, Albers GW, Steinman L. Recurrent transverse myelitis, myasthenia gravis, and autoantibodies. Annals of Neurology. 32: 407-9. PMID 1416813 DOI: 10.1002/Ana.410320319 |
0.314 |
|
| 1992 |
Gautam AM, Pearson CI, Smilek DE, Steinman L, McDevitt HO. A polyalanine peptide with only five native myelin basic protein residues induces autoimmune encephalomyelitis. The Journal of Experimental Medicine. 176: 605-9. PMID 1380066 DOI: 10.1084/Jem.176.2.605 |
0.342 |
|
| 1992 |
Steinman L, Oksenberg JR, Bernard CA. Polymorphism in MS. Neurology. 42: 466-7. PMID 1346550 DOI: 10.1212/Wnl.42.2.466-B |
0.303 |
|
| 1992 |
De Magistris MT, Di Tommaso A, Domenighini M, Censini S, Tagliabue A, Oksenberg JR, Steinman L, Judd AK, O'Sullivan D, Rappuoli R. Interaction of the pertussis toxin peptide containing residues 30-42 with DR1 and the T-cell receptors of 12 human T-cell clones. Proceedings of the National Academy of Sciences of the United States of America. 89: 2990-4. PMID 1313575 DOI: 10.1073/Pnas.89.7.2990 |
0.338 |
|
| 1992 |
Smilek DE, Gautam AM, Pearson C, Steinman L, McDevitt HO. EAE: a model for immune intervention with synthetic peptides. International Reviews of Immunology. 9: 223-30. PMID 1285062 DOI: 10.3109/08830189209061792 |
0.336 |
|
| 1992 |
Panzara MA, Oksenberg JR, Steinman L. The polymerase chain reaction for detection of T-cell antigen receptor expression Current Biology. 2: 250. DOI: 10.1016/0960-9822(92)90365-H |
0.301 |
|
| 1991 |
Oksenberg JR, Mantegazza R, Sakai K, Bernard CC, Steinman L. HTLV-I sequences are not detected in peripheral blood genomic DNA or in brain cDNA of multiple sclerosis patients. Annals of Neurology. 28: 574-7. PMID 2252368 DOI: 10.1002/Ana.410280416 |
0.355 |
|
| 1991 |
Mantegazza R, Hughes SM, Mitchell D, Travis M, Blau HM, Steinman L. Modulation of MHC class II antigen expression in human myoblasts after treatment with IFN-gamma. Neurology. 41: 1128-32. PMID 1906147 DOI: 10.1212/Wnl.41.7.1128 |
0.309 |
|
| 1991 |
Kan-Mitchell J, Liggett PE, Harel W, Steinman L, Nitta T, Oksenberg JR, Posner MR, Mitchell MS. Lymphocytes cytotoxic to uveal and skin melanoma cells from peripheral blood of ocular melanoma patients. Cancer Immunology, Immunotherapy : Cii. 33: 333-40. PMID 1831067 DOI: 10.1007/Bf01756599 |
0.351 |
|
| 1991 |
Steinman L. Prospects for Immunotherapy Directed to the T Cell Receptor in Human Autoimmune Diseasea Annals of the New York Academy of Sciences. 636: 147-153. PMID 1724361 DOI: 10.1111/J.1749-6632.1991.Tb33445.X |
0.341 |
|
| 1991 |
Smilek DE, Wraith DC, Hodgkinson S, Dwivedy S, Steinman L, McDevitt HO. A single amino acid change in a myelin basic protein peptide confers the capacity to prevent rather than induce experimental autoimmune encephalomyelitis. Proceedings of the National Academy of Sciences of the United States of America. 88: 9633-7. PMID 1719536 DOI: 10.1073/Pnas.88.21.9633 |
0.377 |
|
| 1991 |
Steinman L. The development of rational strategies for selective immunotherapy against autoimmune demyelinating disease. Advances in Immunology. 49: 357-379. PMID 1713016 DOI: 10.1016/S0065-2776(08)60779-8 |
0.424 |
|
| 1991 |
Melms A, Oksenberg J, Malcherek G, Lindstrom J, Müller CA, Steinman L. T cell receptor variability in myasthenia gravis Journal of Neuroimmunology. 35: 105. DOI: 10.1016/0165-5728(91)91033-9 |
0.305 |
|
| 1991 |
Panzara MA, Oksenberg JR, Begovich A, Erlich H, Murray R, Appel SH, Steinman L. Restricted T-cell receptor usage in spinal cord and brain of patients with amyotrophic lateral sclerosis Journal of Neuroimmunology. 35: 79. DOI: 10.1016/0165-5728(91)90984-F |
0.316 |
|
| 1990 |
Oksenberg JR, Steinman L. The role of the MHC and T-cell receptor in susceptibility to multiple sclerosis. Current Opinion in Immunology. 2: 619-21. PMID 2700905 DOI: 10.1016/0952-7915(90)90021-8 |
0.304 |
|
| 1990 |
Nitta T, Oksenberg JR, Rao NA, Steinman L. Predominant expression of T cell receptor V alpha 7 in tumor-infiltrating lymphocytes of uveal melanoma. Science (New York, N.Y.). 249: 672-4. PMID 2382141 DOI: 10.1126/Science.2382141 |
0.312 |
|
| 1990 |
Steinman L. Immunogenetic mechanisms in myasthenia gravis. Progress in Brain Research. 84: 117-124. PMID 2267289 DOI: 10.1016/S0079-6123(08)60895-X |
0.389 |
|
| 1990 |
Steinman L, Mantegazza R. Prospects for specific immunotherapy in myasthenia gravis. The Faseb Journal. 4: 2726-2731. PMID 2197152 DOI: 10.1096/Fasebj.4.10.2197152 |
0.38 |
|
| 1990 |
Steinman L. The use of monoclonal antibodies for treatment of autoimmune disease. Journal of Clinical Immunology. 10. PMID 2081787 DOI: 10.1007/Bf00918689 |
0.4 |
|
| 1990 |
Oksenberg JR, Stuart S, Begovich AB, Bell RB, Erlich HA, Steinman L, Bernard CCA. Limited heterogeneity of rearranged T-cell receptor Vα transcripts in brains of multiple sclerosis patients Nature. 345: 344-346. PMID 1971424 DOI: 10.1038/345344A0 |
0.391 |
|
| 1990 |
Wraith DC, Smilek DE, Mitchell DJ, Steinman L, McDevitt HO. T cell recognition in experimental autoimmune encephalomyelitis: prospects for immune intervention with synthetic peptides. International Reviews of Immunology. 6: 37-47. PMID 1715375 DOI: 10.3109/08830189009056616 |
0.375 |
|
| 1990 |
Powell MB, Mitchell D, Lederman J, Buckmeier J, Zamvil SS, Graham M, Ruddle NH, Steinman L. Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity. International Immunology. 2: 539-44. PMID 1707660 DOI: 10.1093/Intimm/2.6.539 |
0.326 |
|
| 1990 |
Brocke S, Dayan M, Steinman L, Rothbard J, Mozes E. Inhibition of T cell proliferation specific for acetylcholine receptor epitopes related to myasthenia gravis with antibody to T cell receptor or with competitive synthetic polymers. International Immunology. 2: 735-42. PMID 1707306 DOI: 10.1093/Intimm/2.8.735 |
0.322 |
|
| 1989 |
Wraith DC, McDevitt HO, Steinman L, Acha-Orbea H. T cell recognition as the target for immune intervention in autoimmune disease. Cell. 57: 709-15. PMID 2655929 DOI: 10.1016/0092-8674(89)90786-1 |
0.369 |
|
| 1989 |
Acha-Orbea H, Steinman L, McDevitt HO. T cell receptors in murine autoimmune diseases. Annual Review of Immunology. 7: 371-405. PMID 2653372 DOI: 10.1146/Annurev.Iy.07.040189.002103 |
0.327 |
|
| 1989 |
Acha-Orbea H, Steinman L, McDevitt HO. T cell receptors in autoimmune disease as targets for immune intervention. Genome. 31: 656-61. PMID 2483695 DOI: 10.1139/G89-120 |
0.4 |
|
| 1989 |
Sakai K, Zamvil SS, Mitchell DJ, Hodgkinson S, Rothbard JB, Steinman L. Prevention of experimental encephalomyelitis with peptides that block interaction of T cells with major histocompatibility complex proteins. Proceedings of the National Academy of Sciences of the United States of America. 86: 9470-4. PMID 2480602 DOI: 10.1073/Pnas.86.23.9470 |
0.371 |
|
| 1989 |
Wraith DC, Smilek DE, Mitchell DJ, Steinman L, McDevitt HO. Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy. Cell. 59: 247-55. PMID 2478291 DOI: 10.1016/0092-8674(89)90287-0 |
0.376 |
|
| 1989 |
Brocke S, Brautbar C, Steinman L, Abramsky O, Rothbard J, Neumann D, Fuchs S, Mozes E. In vitro proliferative responses and antibody titers specific to human acetylcholine receptor synthetic peptides in patients with myasthenia gravis and relation to HLA class II genes. The Journal of Clinical Investigation. 82: 1894-900. PMID 2461962 DOI: 10.1172/Jci113807 |
0.309 |
|
| 1989 |
Steinman L. Immunogenetics of autoimmune disease Journal of Autoimmunity. 2: 951-952. DOI: 10.1016/0896-8411(89)90099-1 |
0.32 |
|
| 1988 |
Todd JA, Acha-Orbea H, Bell JI, Chao N, Fronek Z, Jacob CO, McDermott M, Sinha AA, Timmerman L, Steinman L. A molecular basis for MHC class II--associated autoimmunity. Science (New York, N.Y.). 240: 1003-9. PMID 3368786 DOI: 10.1126/Science.3368786 |
0.338 |
|
| 1988 |
Jonker M, van Lambalgen R, Mitchell DJ, Durham SK, Steinman L. Successful treatment of EAE in rhesus monkeys with MHC class II specific monoclonal antibodies. Journal of Autoimmunity. 1: 399-414. PMID 3254183 DOI: 10.1016/0896-8411(88)90064-9 |
0.318 |
|
| 1988 |
Waldor MK, O'Hearn M, Sriram S, Steinman L. Treatment of experimental autoimmune myasthenia gravis with monoclonal antibodies to immune response gene products. Annals of the New York Academy of Sciences. 505: 655-68. PMID 2961299 DOI: 10.1111/J.1749-6632.1987.Tb51334.X |
0.306 |
|
| 1988 |
Sinha AA, Brautbar C, Szafer F, Friedmann A, Tzfoni E, Todd JA, Steinman L, McDevitt HO. A newly characterized HLA DQ beta allele associated with pemphigus vulgaris. Science (New York, N.Y.). 239: 1026-9. PMID 2894075 DOI: 10.1126/Science.2894075 |
0.306 |
|
| 1988 |
Sakai K, Sinha AA, Mitchell DJ, Zamvil SS, Rothbard JB, McDevitt HO, Steinman L. Involvement of distinct murine T-cell receptors in the autoimmune encephalitogenic response to nested epitopes of myelin basic protein. Proceedings of the National Academy of Sciences of the United States of America. 85: 8608-12. PMID 2460872 DOI: 10.1073/Pnas.85.22.8608 |
0.39 |
|
| 1988 |
Oksenberg JR, Judd AK, Ko C, Lim M, Fernandez R, Schoolnik GK, Steinman L. MHC-restricted recognition of immunogenic T cell epitopes of pertussis toxin reveals determinants in man distinct from the ADP-ribosylase active site. Journal of Experimental Medicine. 168: 1855-1864. PMID 2460578 DOI: 10.1084/Jem.168.5.1855 |
0.311 |
|
| 1988 |
Zamvil SS, Mitchell DJ, Powell MB, Sakai K, Rothbard JB, Steinman L. Multiple discrete encephalitogenic epitopes of the autoantigen myelin basic protein include a determinant for I-E class II-restricted T cells. The Journal of Experimental Medicine. 168: 1181-6. PMID 2459291 DOI: 10.1084/Jem.168.3.1181 |
0.401 |
|
| 1988 |
Acha-Orbea H, Mitchell DJ, Timmermann L, Wraith DC, Tausch GS, Waldor MK, Zamvil SS, McDevitt HO, Steinman L. Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention. Cell. 54: 263-73. PMID 2455603 DOI: 10.1016/0092-8674(88)90558-2 |
0.403 |
|
| 1987 |
Vladutiu AO, Steinman L. Inhibition of experimental autoimmune thyroiditis in mice by anti-I-A antibodies. Cellular Immunology. 109: 169-80. PMID 3498540 DOI: 10.1016/0008-8749(87)90302-9 |
0.318 |
|
| 1987 |
Friedmann A, Frankel G, Lorch Y, Steinman L. Monoclonal anti-I-A antibody reverses chronic paralysis and demyelination in Theiler's virus-infected mice: critical importance of timing of treatment. Journal of Virology. 61: 898-903. PMID 3492612 DOI: 10.1128/Jvi.61.3.898-903.1987 |
0.301 |
|
| 1987 |
Gaiser CN, Johnson MJ, de Lange G, Rassenti L, Cavalli-Sforza LL, Steinman L. Susceptibility to multiple sclerosis associated with an immunoglobulin gamma 3 restriction fragment length polymorphism. The Journal of Clinical Investigation. 79: 309-13. PMID 2878940 DOI: 10.1172/Jci112801 |
0.345 |
|
| 1986 |
Steinman L, Waldor MK, Zamvil SS, Lim M, Herzenberg L, Herzenberg L, McDevitt HO, Mitchell D, Sriram S. Therapy of autoimmune diseases with antibody to immune response gene products or to T-cell surface markers. Annals of the New York Academy of Sciences. 475: 274-84. PMID 3098154 DOI: 10.1111/J.1749-6632.1986.Tb20876.X |
0.374 |
|
| 1986 |
Zamvil SS, Mitchell DJ, Moore AC, Kitamura K, Steinman L, Rothbard JB. T-cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis. Nature. 324: 258-60. PMID 2431317 DOI: 10.1038/324258A0 |
0.41 |
|
| 1985 |
Waldor MK, Sriram S, Hardy R, Herzenberg LA, Herzenberg LA, Lanier L, Lim M, Steinman L. Reversal of experimental allergic encephalomyelitis with monoclonal antibody to a T-cell subset marker. Science (New York, N.Y.). 227: 415-7. PMID 3155574 DOI: 10.1126/Science.3155574 |
0.374 |
|
| 1985 |
Zamvil SS, Nelson PA, Mitchell DJ, Knobler RL, Fritz RB, Steinman L. Encephalitogenic T cell clones specific for myelin basic protein. An unusual bias in antigen recognition. The Journal of Experimental Medicine. 162: 2107-24. PMID 2415664 DOI: 10.1084/Jem.162.6.2107 |
0.367 |
|
| 1985 |
Zamvil S, Nelson P, Trotter J, Mitchell D, Knobler R, Fritz R, Steinman L. T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination Nature. 317: 355-358. PMID 2413363 DOI: 10.1038/317355A0 |
0.406 |
|
| 1984 |
Waldor MK, Hardy RR, Hayakawa K, Steinman L, Herzenberg LA, Herzenberg LA. Disappearance and reappearance of B cells after in vivo treatment with monoclonal anti-I-A antibodies. Proceedings of the National Academy of Sciences of the United States of America. 81: 2855-8. PMID 6609367 DOI: 10.1073/Pnas.81.9.2855 |
0.324 |
|
| 1984 |
Steinman L, Sriram S, Waldor MK. Therapy of autoimmune diseases with antibodies to immune response gene products Clinical Immunology Newsletter. 5: 43-45. DOI: 10.1016/S0197-1859(84)80058-8 |
0.33 |
|
| 1983 |
Steinman L, Solomon D, Lim M, Zamvil S, Sriram S. Prevention of experimental allergic encephalitis with in vivo administration of anti I-A antibody. Decreased accumulation of radiolabelled lymph node cells in the central nervous system. Journal of Neuroimmunology. 5: 91-97. PMID 6603474 DOI: 10.1016/0165-5728(83)90029-2 |
0.322 |
|
| 1983 |
Waldor MK, Sriram S, McDevitt HO, Steinman L. In vivo therapy with monoclonal anti-I-A antibody suppresses immune responses to acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America. 80: 2713-7. PMID 6405386 DOI: 10.1073/Pnas.80.9.2713 |
0.331 |
|
| 1983 |
Sriram S, Schwartz G, Steinman L. Administration of myelin basic protein-coupled spleen cells prevents experimental allergic encephalitis. Cellular Immunology. 75: 378-82. PMID 6187481 DOI: 10.1016/0008-8749(83)90335-0 |
0.352 |
|
| 1982 |
Steinman L, Rosenbaum JT, Sriram S, McDevitt HO. In vivo effects of antibodies to immune response gene products: prevention of experimental allergic encephalitis. Proceedings of the National Academy of Sciences of the United States of America. 78: 7111-4. PMID 6947275 DOI: 10.1073/Pnas.78.11.7111 |
0.314 |
|
| 1981 |
Lonai P, Steinman L, Friedman V, Drizlikh G, Puri J. Specificity of antigen binding by T cells; competition between soluble and Ia-associated antigen. European Journal of Immunology. 11: 382-7. PMID 6167448 DOI: 10.1002/Eji.1830110507 |
0.319 |
|
| 1980 |
Steinman L, Cohen I, Teitelbaum D. Natural occurrence of thymocytes that react with myelin basic protein Neurology. 30: 755-755. PMID 6156429 DOI: 10.1212/Wnl.30.7.755 |
0.316 |
|
| 1979 |
Lonai P, Puri J, Zeicher M, Steinman L. Regulation of antigen binding to T cells: the role of products of adherent cells, and the H-2 restriction of the antigen bound. Advances in Experimental Medicine and Biology. 121: 451-8. PMID 121201 DOI: 10.1007/978-1-4684-3593-1_40 |
0.349 |
|
| 1978 |
Lonai P, Ben-Neriah Y, Steinman L, Givol D. Selective participation of immunoglobulin V region and major histocompatibility complex products in antigen binding by T cells. European Journal of Immunology. 8: 827-32. PMID 103727 DOI: 10.1002/Eji.1830081202 |
0.335 |
|
| 1978 |
Steinman L, Tzehoval E, Cohen IR, Segal S, Glickman E. Sequential interaction of macrophages, initiator T lymphocytes and recruited T lymphocytes in a cell-mediated immune response to soluble antigen European Journal of Immunology. 8: 29-34. PMID 76565 DOI: 10.1002/Eji.1830080107 |
0.341 |
|
| 1977 |
Lonai P, Steinman L. Physiological regulation of antigen binding to T cells: role of a soluble macrophage factor and of interferon. Proceedings of the National Academy of Sciences of the United States of America. 74: 5662-5666. PMID 414224 DOI: 10.1073/Pnas.74.12.5662 |
0.345 |
|
| 1977 |
Steinman L, Cohen IR, Teitelbaum D, Glickman E, Arnon R. Regulation Of Autoimmunity By The Mode Of Presentation Of Autoantigen To Lymphocytes Regulatory Mechanisms in Lymphocyte Activation. 728-729. DOI: 10.1016/B978-0-12-458050-3.50143-0 |
0.316 |
|
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