Year |
Citation |
Score |
2016 |
Foster SA, Whalen DM, Özen A, Wongchenko MJ, Yin J, Yen I, Schaefer G, Mayfield JD, Chmielecki J, Stephens PJ, Albacker LA, Yan Y, Song K, Hatzivassiliou G, Eigenbrot C, ... ... Manning G, et al. Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2. Cancer Cell. PMID 26996308 DOI: 10.1016/j.ccell.2016.02.010 |
1 |
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2015 |
Babbitt PC, Bagos PG, Bairoch A, Bateman A, Chatonnet A, Chen MJ, Craik DJ, Finn RD, Gloriam D, Haft DH, Henrissat B, Holliday GL, Isberg V, Kaas Q, Landsman D, ... ... Manning G, et al. Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat. Database : the Journal of Biological Databases and Curation. 2015: bav063. PMID 26284514 DOI: 10.1093/database/bav063 |
1 |
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2015 |
Rudolph J, Aliagas I, Crawford JJ, Mathieu S, Lee W, Chao Q, Dong P, Rouge L, Wang W, Heise C, Murray LJ, La H, Liu Y, Manning G, Diederich F, et al. Leveraging the Pre-DFG Residue Thr-406 To Obtain High Kinase Selectivity in an Aminopyrazole-Type PAK1 Inhibitor Series. Acs Medicinal Chemistry Letters. 6: 711-5. PMID 26101579 DOI: 10.1021/acsmedchemlett.5b00151 |
1 |
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2015 |
Holliday GL, Bairoch A, Bagos PG, Chatonnet A, Craik DJ, Finn RD, Henrissat B, Landsman D, Manning G, Nagano N, O'Donovan C, Pruitt KD, Rawlings ND, Saier M, Sowdhamini R, et al. Key challenges for the creation and maintenance of specialist protein resources. Proteins. 83: 1005-13. PMID 25820941 DOI: 10.1002/prot.24803 |
1 |
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2015 |
Klijn C, Durinck S, Stawiski EW, Haverty PM, Jiang Z, Liu H, Degenhardt J, Mayba O, Gnad F, Liu J, Pau G, Reeder J, Cao Y, Mukhyala K, Selvaraj SK, ... ... Manning G, et al. A comprehensive transcriptional portrait of human cancer cell lines. Nature Biotechnology. 33: 306-12. PMID 25485619 DOI: 10.1038/nbt.3080 |
1 |
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2015 |
Daemen A, Peterson D, Sahu N, McCord R, Du X, Liu B, Kowanetz K, Hong R, Moffat J, Gao M, Boudreau A, Mroue R, Corson L, O'Brien T, Qing J, ... ... Manning G, et al. Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors Proceedings of the National Academy of Sciences of the United States of America. 112: E4410-E4417. DOI: 10.1073/pnas.1501605112 |
1 |
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2015 |
Hunter T, Manning G. The eukaryotic protein kinase superfamily and the emergence of receptor tyrosine kinases Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease. 1-15. DOI: 10.1007/978-1-4939-2053-2_1 |
1 |
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2014 |
Chipman AD, Ferrier DE, Brena C, Qu J, Hughes DS, Schröder R, Torres-Oliva M, Znassi N, Jiang H, Almeida FC, Alonso CR, Apostolou Z, Aqrawi P, Arthur W, Barna JC, ... ... Manning G, et al. The first myriapod genome sequence reveals conservative arthropod gene content and genome organisation in the centipede Strigamia maritima. Plos Biology. 12: e1002005. PMID 25423365 DOI: 10.1371/journal.pbio.1002005 |
1 |
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2014 |
Baird NA, Douglas PM, Simic MS, Grant AR, Moresco JJ, Wolff SC, Yates JR, Manning G, Dillin A. HSF-1-mediated cytoskeletal integrity determines thermotolerance and life span. Science (New York, N.Y.). 346: 360-3. PMID 25324391 DOI: 10.1126/science.1253168 |
1 |
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2014 |
Murphy JM, Zhang Q, Young SN, Reese ML, Bailey FP, Eyers PA, Ungureanu D, Hammaren H, Silvennoinen O, Varghese LN, Chen K, Tripaydonis A, Jura N, Fukuda K, Qin J, ... ... Manning G, et al. A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties. The Biochemical Journal. 457: 323-34. PMID 24107129 DOI: 10.1042/BJ20131174 |
1 |
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2013 |
Dellas N, Thomas ST, Manning G, Noel JP. Discovery of a metabolic alternative to the classical mevalonate pathway. Elife. 2: e00672. PMID 24327557 DOI: 10.7554/eLife.00672 |
1 |
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2013 |
Pottekat A, Becker S, Spencer KR, Yates JR, Manning G, Itkin-Ansari P, Balch WE. Insulin biosynthetic interaction network component, TMEM24, facilitates insulin reserve pool release. Cell Reports. 4: 921-30. PMID 24012759 DOI: 10.1016/j.celrep.2013.07.050 |
1 |
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2013 |
Suga H, Chen Z, de Mendoza A, Sebé-Pedrós A, Brown MW, Kramer E, Carr M, Kerner P, Vervoort M, Sánchez-Pons N, Torruella G, Derelle R, Manning G, Lang BF, Russ C, et al. The Capsaspora genome reveals a complex unicellular prehistory of animals. Nature Communications. 4: 2325. PMID 23942320 DOI: 10.1038/ncomms3325 |
1 |
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2013 |
Gnad F, Baucom A, Mukhyala K, Manning G, Zhang Z. Assessment of computational methods for predicting the effects of missense mutations in human cancers. Bmc Genomics. 14: S7. PMID 23819521 DOI: 10.1186/1471-2164-14-S3-S7 |
1 |
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2013 |
Fairclough SR, Chen Z, Kramer E, Zeng Q, Young S, Robertson HM, Begovic E, Richter DJ, Russ C, Westbrook MJ, Manning G, Lang BF, Haas B, Nusbaum C, King N. Premetazoan genome evolution and the regulation of cell differentiation in the choanoflagellate Salpingoeca rosetta. Genome Biology. 14: R15. PMID 23419129 DOI: 10.1186/gb-2013-14-2-r15 |
1 |
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2013 |
Teh PG, Chen MJ, Engel JL, Worby CA, Manning G, Dixon JE, Zhang J. Identification of a mammalian-type phosphatidylglycerophosphate phosphatase in the Eubacterium Rhodopirellula baltica. The Journal of Biological Chemistry. 288: 5176-85. PMID 23293031 DOI: 10.1074/jbc.M112.413617 |
1 |
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2012 |
Vilchez D, Morantte I, Liu Z, Douglas PM, Merkwirth C, Rodrigues AP, Manning G, Dillin A. RPN-6 determines C. elegans longevity under proteotoxic stress conditions. Nature. 489: 263-8. PMID 22922647 DOI: 10.1038/nature11315 |
1 |
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2012 |
Ishikawa HO, Xu A, Ogura E, Manning G, Irvine KD. The Raine syndrome protein FAM20C is a Golgi kinase that phosphorylates bio-mineralization proteins. Plos One. 7: e42988. PMID 22900076 DOI: 10.1371/journal.pone.0042988 |
1 |
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2012 |
Ngaki MN, Louie GV, Philippe RN, Manning G, Pojer F, Bowman ME, Li L, Larsen E, Wurtele ES, Noel JP. Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis. Nature. 485: 530-3. PMID 22622584 DOI: 10.1038/nature11009 |
1 |
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2012 |
Suga H, Dacre M, de Mendoza A, Shalchian-Tabrizi K, Manning G, Ruiz-Trillo I. Genomic survey of premetazoans shows deep conservation of cytoplasmic tyrosine kinases and multiple radiations of receptor tyrosine kinases. Science Signaling. 5: ra35. PMID 22550341 DOI: 10.1126/scisignal.2002733 |
1 |
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2011 |
Mattoo S, Durrant E, Chen MJ, Xiao J, Lazar CS, Manning G, Dixon JE, Worby CA. Comparative analysis of Histophilus somni immunoglobulin-binding protein A (IbpA) with other fic domain-containing enzymes reveals differences in substrate and nucleotide specificities. The Journal of Biological Chemistry. 286: 32834-42. PMID 21795713 DOI: 10.1074/jbc.M111.227603 |
1 |
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2011 |
Manning G, Reiner DS, Lauwaet T, Dacre M, Smith A, Zhai Y, Svard S, Gillin FD. The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology. Genome Biology. 12: R66. PMID 21787419 DOI: 10.1186/gb-2011-12-7-r66 |
1 |
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2011 |
Xiao J, Engel JL, Zhang J, Chen MJ, Manning G, Dixon JE. Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis. Proceedings of the National Academy of Sciences of the United States of America. 108: 11860-5. PMID 21730175 DOI: 10.1073/pnas.1109290108 |
1 |
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2011 |
de Cárcer G, Manning G, Malumbres M. From Plk1 to Plk5: functional evolution of polo-like kinases. Cell Cycle (Georgetown, Tex.). 10: 2255-62. PMID 21654194 DOI: 10.4161/cc.10.14.16494 |
1 |
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2011 |
Banks JA, Nishiyama T, Hasebe M, Bowman JL, Gribskov M, dePamphilis C, Albert VA, Aono N, Aoyama T, Ambrose BA, Ashton NW, Axtell MJ, Barker E, Barker MS, Bennetzen JL, ... ... Manning G, et al. The Selaginella genome identifies genetic changes associated with the evolution of vascular plants. Science (New York, N.Y.). 332: 960-3. PMID 21551031 DOI: 10.1126/science.1203810 |
1 |
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2011 |
Mair W, Morantte I, Rodrigues AP, Manning G, Montminy M, Shaw RJ, Dillin A. Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB. Nature. 470: 404-8. PMID 21331044 DOI: 10.1038/nature09706 |
1 |
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2011 |
de Cárcer G, Escobar B, Higuero AM, GarcÃa L, Ansón A, Pérez G, Mollejo M, Manning G, Meléndez B, Abad-RodrÃguez J, Malumbres M. Plk5, a polo box domain-only protein with specific roles in neuron differentiation and glioblastoma suppression. Molecular and Cellular Biology. 31: 1225-39. PMID 21245385 DOI: 10.1128/MCB.00607-10 |
1 |
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2010 |
Manning G, Scheeff E. How the vertebrates were made: selective pruning of a double-duplicated genome. Bmc Biology. 8: 144. PMID 21144066 DOI: 10.1186/1741-7007-8-144 |
1 |
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2010 |
Srivastava M, Simakov O, Chapman J, Fahey B, Gauthier ME, Mitros T, Richards GS, Conaco C, Dacre M, Hellsten U, Larroux C, Putnam NH, Stanke M, Adamska M, Darling A, ... ... Manning G, et al. The Amphimedon queenslandica genome and the evolution of animal complexity. Nature. 466: 720-6. PMID 20686567 DOI: 10.1038/nature09201 |
1 |
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2010 |
Stajich JE, Wilke SK, Ahrén D, Au CH, Birren BW, Borodovsky M, Burns C, Canbäck B, Casselton LA, Cheng CK, Deng J, Dietrich FS, Fargo DC, Farman ML, Gathman AC, ... ... Manning G, et al. Insights into evolution of multicellular fungi from the assembled chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus). Proceedings of the National Academy of Sciences of the United States of America. 107: 11889-94. PMID 20547848 DOI: 10.1073/pnas.1003391107 |
1 |
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2010 |
Walker CB, de la Torre JR, Klotz MG, Urakawa H, Pinel N, Arp DJ, Brochier-Armanet C, Chain PS, Chan PP, Gollabgir A, Hemp J, Hügler M, Karr EA, Könneke M, Shin M, ... ... Manning G, et al. Nitrosopumilus maritimus genome reveals unique mechanisms for nitrification and autotrophy in globally distributed marine crenarchaea. Proceedings of the National Academy of Sciences of the United States of America. 107: 8818-23. PMID 20421470 DOI: 10.1073/pnas.0913533107 |
1 |
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2010 |
Scheeff ED, Axelrod HL, Miller MD, Chiu HJ, Deacon AM, Wilson IA, Manning G. Genomics, evolution, and crystal structure of a new family of bacterial spore kinases. Proteins. 78: 1470-82. PMID 20077512 DOI: 10.1002/prot.22663 |
1 |
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2010 |
Hutt DM, Herman D, Rodrigues AP, Noel S, Pilewski JM, Matteson J, Hoch B, Kellner W, Kelly JW, Schmidt A, Thomas PJ, Matsumura Y, Skach WR, Gentzsch M, Riordan JR, ... ... Manning G, et al. Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis. Nature Chemical Biology. 6: 25-33. PMID 19966789 DOI: 10.1038/nchembio.275 |
1 |
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2010 |
Manning G, Hunter T. Eukaryotic kinomes. genomics and evolution of protein kinases Handbook of Cell Signaling, 2/E. 2: 393-397. DOI: 10.1016/B978-0-12-374145-5.00056-5 |
1 |
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2009 |
Nathanson JL, Jappelli R, Scheeff ED, Manning G, Obata K, Brenner S, Callaway EM. Short Promoters in Viral Vectors Drive Selective Expression in Mammalian Inhibitory Neurons, but do not Restrict Activity to Specific Inhibitory Cell-Types. Frontiers in Neural Circuits. 3: 19. PMID 19949461 DOI: 10.3389/neuro.04.019.2009 |
1 |
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2009 |
Malumbres M, Harlow E, Hunt T, Hunter T, Lahti JM, Manning G, Morgan DO, Tsai LH, Wolgemuth DJ. Cyclin-dependent kinases: a family portrait. Nature Cell Biology. 11: 1275-6. PMID 19884882 DOI: 10.1038/ncb1109-1275 |
1 |
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2009 |
Zhang YW, Brognard J, Coughlin C, You Z, Dolled-Filhart M, Aslanian A, Manning G, Abraham RT, Hunter T. The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress. Molecular Cell. 35: 442-53. PMID 19716789 DOI: 10.1016/j.molcel.2009.06.030 |
1 |
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2009 |
Bomati EK, Manning G, Deheyn DD. Amphioxus encodes the largest known family of green fluorescent proteins, which have diversified into distinct functional classes. Bmc Evolutionary Biology. 9: 77. PMID 19379521 DOI: 10.1186/1471-2148-9-77 |
1 |
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2009 |
Copp J, Manning G, Hunter T. TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2. Cancer Research. 69: 1821-7. PMID 19244117 DOI: 10.1158/0008-5472.CAN-08-3014 |
1 |
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2009 |
Scheeff ED, Eswaran J, Bunkoczi G, Knapp S, Manning G. Structure of the pseudokinase VRK3 reveals a degraded catalytic site, a highly conserved kinase fold, and a putative regulatory binding site. Structure (London, England : 1993). 17: 128-38. PMID 19141289 DOI: 10.1016/j.str.2008.10.018 |
1 |
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2008 |
O'Maille PE, Malone A, Dellas N, Andes Hess B, Smentek L, Sheehan I, Greenhagen BT, Chappell J, Manning G, Noel JP. Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases. Nature Chemical Biology. 4: 617-23. PMID 18776889 DOI: 10.1038/nchembio.113 |
1 |
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2008 |
Manning G, Young SL, Miller WT, Zhai Y. The protist, Monosiga brevicollis, has a tyrosine kinase signaling network more elaborate and diverse than found in any known metazoan. Proceedings of the National Academy of Sciences of the United States of America. 105: 9674-9. PMID 18621719 DOI: 10.1073/pnas.0801314105 |
1 |
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2008 |
Vilar M, Chou HT, Lührs T, Maji SK, Riek-Loher D, Verel R, Manning G, Stahlberg H, Riek R. The fold of alpha-synuclein fibrils. Proceedings of the National Academy of Sciences of the United States of America. 105: 8637-42. PMID 18550842 DOI: 10.1073/pnas.0712179105 |
1 |
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2008 |
King N, Westbrook MJ, Young SL, Kuo A, Abedin M, Chapman J, Fairclough S, Hellsten U, Isogai Y, Letunic I, Marr M, Pincus D, Putnam N, Rokas A, Wright KJ, ... ... Manning G, et al. The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans. Nature. 451: 783-8. PMID 18273011 DOI: 10.1038/nature06617 |
1 |
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2007 |
Perrin MH, Grace CR, Digruccio MR, Fischer WH, Maji SK, Cantle JP, Smith S, Manning G, Vale WW, Riek R. Distinct structural and functional roles of conserved residues in the first extracellular domain of receptors for corticotropin-releasing factor and related G-protein-coupled receptors. The Journal of Biological Chemistry. 282: 37529-36. PMID 17940290 DOI: 10.1074/jbc.M703748200 |
1 |
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2007 |
Morrison HG, McArthur AG, Gillin FD, Aley SB, Adam RD, Olsen GJ, Best AA, Cande WZ, Chen F, Cipriano MJ, Davids BJ, Dawson SC, Elmendorf HG, Hehl AB, Holder ME, ... ... Manning G, et al. Genomic minimalism in the early diverging intestinal parasite Giardia lamblia. Science (New York, N.Y.). 317: 1921-6. PMID 17901334 DOI: 10.1126/science.1143837 |
1 |
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2007 |
Kannan N, Taylor SS, Zhai Y, Venter JC, Manning G. Structural and functional diversity of the microbial kinome. Plos Biology. 5: e17. PMID 17355172 DOI: 10.1371/journal.pbio.0050017 |
1 |
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2007 |
Yooseph S, Sutton G, Rusch DB, Halpern AL, Williamson SJ, Remington K, Eisen JA, Heidelberg KB, Manning G, Li W, Jaroszewski L, Cieplak P, Miller CS, Li H, Mashiyama ST, et al. The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families. Plos Biology. 5: e16. PMID 17355171 DOI: 10.1371/journal.pbio.0050016 |
1 |
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2006 |
Bradham CA, Foltz KR, Beane WS, Arnone MI, Rizzo F, Coffman JA, Mushegian A, Goel M, Morales J, Geneviere AM, Lapraz F, Robertson AJ, Kelkar H, Loza-Coll M, Townley IK, ... ... Manning G, et al. The sea urchin kinome: a first look. Developmental Biology. 300: 180-93. PMID 17027740 DOI: 10.1016/j.ydbio.2006.08.074 |
1 |
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2006 |
Eisen JA, Coyne RS, Wu M, Wu D, Thiagarajan M, Wortman JR, Badger JH, Ren Q, Amedeo P, Jones KM, Tallon LJ, Delcher AL, Salzberg SL, Silva JC, Haas BJ, ... ... Manning G, et al. Macronuclear genome sequence of the ciliate Tetrahymena thermophila, a model eukaryote. Plos Biology. 4: e286. PMID 16933976 DOI: 10.1371/journal.pbio.0040286 |
1 |
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2006 |
Wloga D, Camba A, Rogowski K, Manning G, Jerka-Dziadosz M, Gaertig J. Members of the NIMA-related kinase family promote disassembly of cilia by multiple mechanisms. Molecular Biology of the Cell. 17: 2799-810. PMID 16611747 DOI: 10.1091/mbc.E05-05-0450 |
1 |
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2006 |
Goldberg JM, Manning G, Liu A, Fey P, Pilcher KE, Xu Y, Smith JL. The dictyostelium kinome--analysis of the protein kinases from a simple model organism. Plos Genetics. 2: e38. PMID 16596165 DOI: 10.1371/journal.pgen.0020038 |
1 |
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2005 |
Manning G. Genomic overview of protein kinases. Wormbook : the Online Review of C. Elegans Biology. 1-19. PMID 18050405 DOI: 10.1895/wormbook.1.60.1 |
1 |
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2004 |
Caenepeel S, Charydczak G, Sudarsanam S, Hunter T, Manning G. The mouse kinome: discovery and comparative genomics of all mouse protein kinases. Proceedings of the National Academy of Sciences of the United States of America. 101: 11707-12. PMID 15289607 DOI: 10.1073/pnas.0306880101 |
1 |
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2003 |
Wright JH, Wang X, Manning G, LaMere BJ, Le P, Zhu S, Khatry D, Flanagan PM, Buckley SD, Whyte DB, Howlett AR, Bischoff JR, Lipson KE, Jallal B. The STE20 kinase HGK is broadly expressed in human tumor cells and can modulate cellular transformation, invasion, and adhesion. Molecular and Cellular Biology. 23: 2068-82. PMID 12612079 DOI: 10.1128/MCB.23.6.2068-2082.2003 |
1 |
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2003 |
Hunter T, Manning G. Eukaryotic Kinomes: Genomic Cataloguing of Protein Kinases and Their Evolution Handbook of Cell Signaling. 1: 373-377. DOI: 10.1016/B978-012124546-7/50427-7 |
1 |
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2002 |
Manning G, Plowman GD, Hunter T, Sudarsanam S. Evolution of protein kinase signaling from yeast to man. Trends in Biochemical Sciences. 27: 514-20. PMID 12368087 DOI: 10.1016/S0968-0004(02)02179-5 |
1 |
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1996 |
Samakovlis C, Manning G, Steneberg P, Hacohen N, Cantera R, Krasnow MA. Genetic control of epithelial tube fusion during Drosophila tracheal development. Development (Cambridge, England). 122: 3531-6. PMID 8951068 |
0.4 |
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1996 |
Samakovlis C, Hacohen N, Manning G, Sutherland DC, Guillemin K, Krasnow MA. Development of the Drosophila tracheal system occurs by a series of morphologically distinct but genetically coupled branching events. Development (Cambridge, England). 122: 1395-407. PMID 8625828 |
0.4 |
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1991 |
Krasnow MA, Cumberledge S, Manning G, Herzenberg LA, Nolan GP. Whole animal cell sorting of Drosophila embryos. Science (New York, N.Y.). 251: 81-5. PMID 1898782 DOI: 10.1126/science.1898782 |
0.4 |
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