Barbara Graves - Publications

Affiliations: 
University of Utah, Salt Lake City, UT 

68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Perez-Borrajero C, Lin CS, Okon M, Scheu K, Graves BJ, Murphy MEP, McIntosh LP. The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor. Journal of Molecular Biology. PMID 30597162 DOI: 10.1016/j.jmb.2018.12.011  0.48
2017 Currie SL, Doane JJ, Evans KS, Bhachech N, Madison BJ, Lau DKW, McIntosh LP, Skalicky JJ, Clark KA, Graves BJ. ETV4 and AP1 transcription factors form multivalent interactions with three sites on the MED25 activator-interacting domain. Journal of Molecular Biology. PMID 28728983 DOI: 10.1016/j.jmb.2017.06.024  0.48
2017 Currie SL, Lau DK, Doane JJ, Whitby FG, Okon M, McIntosh LP, Graves BJ. Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5. Nucleic Acids Research. PMID 28161714 DOI: 10.1093/nar/gkx068  0.48
2016 Kikani CK, Wu X, Paul L, Sabic H, Shen Z, Shakya A, Keefe A, Villanueva C, Kardon G, Graves B, Tantin D, Rutter J. Pask integrates hormonal signaling with histone modification via Wdr5 phosphorylation to drive myogenesis. Elife. 5. PMID 27661449 DOI: 10.7554/eLife.17985  1
2016 Desjardins G, Okon M, Graves BJ, McIntosh LP. Conformational dynamics and the binding of specific and non-specific DNA by the autoinhibited transcription factor Ets-1. Biochemistry. PMID 27362745 DOI: 10.1021/acs.biochem.6b00460  0.48
2016 De S, Okon M, Graves BJ, McIntosh LP. Autoinhibition of ETV6 DNA-binding is established by the stability of its inhibitory helix. Journal of Molecular Biology. PMID 26920109 DOI: 10.1016/j.jmb.2016.02.020  1
2015 Huang F, Ramakrishnan S, Pokhrel S, Pflueger C, Parnell TJ, Kasten MM, Currie SL, Bhachech N, Horikoshi M, Graves BJ, Cairns BR, Bhaskara S, Chandrasekharan MB. Interaction of the Jhd2 H3K4 demethylase with chromatin is controlled by histone H2A surfaces and restricted by H2B ubiquitination. The Journal of Biological Chemistry. PMID 26451043 DOI: 10.1074/jbc.M115.693085  1
2014 Desjardins G, Meeker CA, Bhachech N, Currie SL, Okon M, Graves BJ, McIntosh LP. Synergy of aromatic residues and phosphoserines within the intrinsically disordered DNA-binding inhibitory elements of the Ets-1 transcription factor. Proceedings of the National Academy of Sciences of the United States of America. 111: 11019-24. PMID 25024220 DOI: 10.1073/pnas.1401891111  1
2014 Clark KA, Graves BJ. Dual views of SRF: a genomic exposure. Genes & Development. 28: 926-8. PMID 24788515 DOI: 10.1101/gad.242420.114  1
2014 De S, Chan AC, Coyne HJ, Bhachech N, Hermsdorf U, Okon M, Murphy ME, Graves BJ, McIntosh LP. Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6. Journal of Molecular Biology. 426: 1390-406. PMID 24333486 DOI: 10.1016/j.jmb.2013.11.031  1
2012 Ramirez K, Chandler KJ, Spaulding C, Zandi S, Sigvardsson M, Graves BJ, Kee BL. Gene deregulation and chronic activation in natural killer cells deficient in the transcription factor ETS1. Immunity. 36: 921-32. PMID 22608498 DOI: 10.1016/j.immuni.2012.04.006  1
2012 Coyne HJ, De S, Okon M, Green SM, Bhachech N, Graves BJ, McIntosh LP. Autoinhibition of ETV6 (TEL) DNA binding: appended helices sterically block the ETS domain. Journal of Molecular Biology. 421: 67-84. PMID 22584210 DOI: 10.1016/j.jmb.2012.05.010  1
2011 Hollenhorst PC, Ferris MW, Hull MA, Chae H, Kim S, Graves BJ. Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells. Genes & Development. 25: 2147-57. PMID 22012618 DOI: 10.1101/gad.17546311  1
2011 Hollenhorst PC, McIntosh LP, Graves BJ. Genomic and biochemical insights into the specificity of ETS transcription factors. Annual Review of Biochemistry. 80: 437-71. PMID 21548782 DOI: 10.1146/annurev.biochem.79.081507.103945  1
2011 Hollenhorst PC, Paul L, Ferris MW, Graves BJ. The ETS gene ETV4 is required for anchorage-independent growth and a cell proliferation gene expression program in PC3 prostate cells. Genes & Cancer. 1: 1044-1052. PMID 21373373 DOI: 10.1177/1947601910395578  1
2010 Thyagarajan B, Blaszczak AG, Chandler KJ, Watts JL, Johnson WE, Graves BJ. ETS-4 is a transcriptional regulator of life span in Caenorhabditis elegans. Plos Genetics. 6: e1001125. PMID 20862312 DOI: 10.1371/journal.pgen.1001125  1
2010 Nelson ML, Kang HS, Lee GM, Blaszczak AG, Lau DK, McIntosh LP, Graves BJ. Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBP. Proceedings of the National Academy of Sciences of the United States of America. 107: 10026-31. PMID 20534573 DOI: 10.1073/pnas.0915137107  1
2010 Oler AJ, Alla RK, Roberts DN, Wong A, Hollenhorst PC, Chandler KJ, Cassiday PA, Nelson CA, Hagedorn CH, Graves BJ, Cairns BR. Human RNA polymerase III transcriptomes and relationships to Pol II promoter chromatin and enhancer-binding factors. Nature Structural & Molecular Biology. 17: 620-8. PMID 20418882 DOI: 10.1038/nsmb.1801  1
2010 Green SM, Coyne HJ, McIntosh LP, Graves BJ. DNA binding by the ETS protein TEL (ETV6) is regulated by autoinhibition and self-association. The Journal of Biological Chemistry. 285: 18496-504. PMID 20400516 DOI: 10.1074/jbc.M109.096958  1
2010 Clement NL, Snell Q, Clement MJ, Hollenhorst PC, Purwar J, Graves BJ, Cairns BR, Johnson WE. The GNUMAP algorithm: unbiased probabilistic mapping of oligonucleotides from next-generation sequencing. Bioinformatics (Oxford, England). 26: 38-45. PMID 19861355 DOI: 10.1093/bioinformatics/btp614  1
2009 Hollenhorst PC, Chandler KJ, Poulsen RL, Johnson WE, Speck NA, Graves BJ. DNA specificity determinants associate with distinct transcription factor functions. Plos Genetics. 5: e1000778. PMID 20019798 DOI: 10.1371/journal.pgen.1000778  1
2009 McIntosh LP, Kang HS, Okon M, Nelson ML, Graves BJ, Brutscher B. Detection and assignment of phosphoserine and phosphothreonine residues by (13)C- (31)P spin-echo difference NMR spectroscopy. Journal of Biomolecular Nmr. 43: 31-7. PMID 19002654 DOI: 10.1007/s10858-008-9287-6  1
2008 Lee GM, Pufall MA, Meeker CA, Kang HS, Graves BJ, McIntosh LP. The affinity of Ets-1 for DNA is modulated by phosphorylation through transient interactions of an unstructured region. Journal of Molecular Biology. 382: 1014-30. PMID 18692067 DOI: 10.1016/j.jmb.2008.07.064  1
2008 Gangwal K, Sankar S, Hollenhorst PC, Kinsey M, Haroldsen SC, Shah AA, Boucher KM, Watkins WS, Jorde LB, Graves BJ, Lessnick SL. Microsatellites as EWS/FLI response elements in Ewing's sarcoma. Proceedings of the National Academy of Sciences of the United States of America. 105: 10149-54. PMID 18626011 DOI: 10.1073/pnas.0801073105  1
2008 Grenningloh R, Miaw SC, Moisan J, Graves BJ, Ho IC. Role of Ets-1 phosphorylation in the effector function of Th cells. European Journal of Immunology. 38: 1700-5. PMID 18465773 DOI: 10.1002/eji.200738112  1
2008 Kang HS, Nelson ML, Mackereth CD, Schärpf M, Graves BJ, McIntosh LP. Identification and structural characterization of a CBP/p300-binding domain from the ETS family transcription factor GABP alpha. Journal of Molecular Biology. 377: 636-46. PMID 18295234 DOI: 10.1016/j.jmb.2008.01.054  1
2007 Hollenhorst PC, Shah AA, Hopkins C, Graves BJ. Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family. Genes & Development. 21: 1882-94. PMID 17652178 DOI: 10.1101/gad.1561707  1
2006 Graves BJ, Tamkun JW. Transcription saga tells developmental stories. Development (Cambridge, England). 133: 4393-7. PMID 17075006 DOI: 10.1242/dev.02639  1
2006 Macauley MS, Errington WJ, Schärpf M, Mackereth CD, Blaszczak AG, Graves BJ, McIntosh LP. Beads-on-a-string, characterization of ETS-1 sumoylated within its flexible N-terminal sequence. The Journal of Biological Chemistry. 281: 4164-72. PMID 16319071 DOI: 10.1074/jbc.M510488200  1
2005 Pufall MA, Lee GM, Nelson ML, Kang HS, Velyvis A, Kay LE, McIntosh LP, Graves BJ. Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured region. Science (New York, N.Y.). 309: 142-5. PMID 15994560 DOI: 10.1126/science.1111915  1
2005 Lee GM, Donaldson LW, Pufall MA, Kang HS, Pot I, Graves BJ, McIntosh LP. The structural and dynamic basis of Ets-1 DNA binding autoinhibition. The Journal of Biological Chemistry. 280: 7088-99. PMID 15591056 DOI: 10.1074/jbc.M410722200  1
2004 Foulds CE, Nelson ML, Blaszczak AG, Graves BJ. Ras/mitogen-activated protein kinase signaling activates Ets-1 and Ets-2 by CBP/p300 recruitment. Molecular and Cellular Biology. 24: 10954-64. PMID 15572696 DOI: 10.1128/MCB.24.24.10954-10964.2004  1
2004 Hollenhorst PC, Jones DA, Graves BJ. Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors. Nucleic Acids Research. 32: 5693-702. PMID 15498926 DOI: 10.1093/nar/gkh906  1
2002 Garvie CW, Pufall MA, Graves BJ, Wolberger C. Structural analysis of the autoinhibition of Ets-1 and its role in protein partnerships. The Journal of Biological Chemistry. 277: 45529-36. PMID 12221090 DOI: 10.1074/jbc.M206327200  1
2002 Pufall MA, Graves BJ. Autoinhibitory domains: modular effectors of cellular regulation. Annual Review of Cell and Developmental Biology. 18: 421-62. PMID 12142282 DOI: 10.1146/annurev.cellbio.18.031502.133614  1
2002 Pufall MA, Graves BJ. Ets-1 flips for new partner Pax-5. Structure (London, England : 1993). 10: 11-4. PMID 11796106 DOI: 10.1016/S0969-2126(01)00701-8  1
2002 Seidel JJ, Graves BJ. An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors. Genes & Development. 16: 127-37. PMID 11782450 DOI: 10.1101/gad.950902  1
2002 Wang H, McIntosh LP, Graves BJ. Inhibitory module of Ets-1 allosterically regulates DNA binding through a dipole-facilitated phosphate contact. The Journal of Biological Chemistry. 277: 2225-33. PMID 11689571 DOI: 10.1074/jbc.M109430200  1
2000 Cowley DO, Graves BJ. Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition Genes and Development. 14: 366-376. PMID 10673508  1
2000 Gu TL, Goetz TL, Graves BJ, Speck NA. Auto-inhibition and partner proteins, core-binding factor beta (CBFbeta) and Ets-1, modulate DNA binding by CBFalpha2 (AML1). Molecular and Cellular Biology. 20: 91-103. PMID 10594012  1
2000 Goetz TL, Gu TL, Speck NA, Graves BJ. Auto-inhibition of Ets-1 is counteracted by DNA binding cooperativity with core-binding factor alpha2. Molecular and Cellular Biology. 20: 81-90. PMID 10594011  1
1999 Dickinson LA, Trauger JW, Baird EE, Dervan PB, Graves BJ, Gottesfeld JM. Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-kappaB, and DNA by a designed DNA-binding ligand. The Journal of Biological Chemistry. 274: 12765-73. PMID 10212261 DOI: 10.1074/jbc.274.18.12765  1
1998 Graves BJ, Cowley DO, Goetz TL, Petersen JM, Jonsen MD, Gillespie ME. Autoinhibition as a transcriptional regulatory mechanism. Cold Spring Harbor Symposia On Quantitative Biology. 63: 621-9. PMID 10384327  1
1998 Myszka DG, Jonsen MD, Graves BJ. Equilibrium analysis of high affinity interactions using BIACORE Analytical Biochemistry. 265: 326-330. PMID 9882410 DOI: 10.1006/abio.1998.2937  1
1998 Slupsky CM, Gentile LN, Donaldson LW, Mackereth CD, Seidel JJ, Graves BJ, Mcintosh LP. Structure of the Ets-1 pointed domain and mitogen-activated protein kinase phosphorylation site Proceedings of the National Academy of Sciences of the United States of America. 95: 12129-12134. PMID 9770451 DOI: 10.1073/pnas.95.21.12129  1
1998 Graves BJ, Petersen JM. Specificity within the ets family of transcription factors Advances in Cancer Research. 75: 1-55. PMID 9709806  1
1998 Graves BJ. Inner workings of a transcription factor partnership Science. 279: 1000-1002. PMID 9490475 DOI: 10.1126/science.279.5353.1000  1
1996 Graves BJ, Gillespie ME, McIntosh LP. DNA binding by the ETS domain Nature. 384: 322. PMID 8934514 DOI: 10.1038/384322a0  1
1996 Skalicky JJ, Donaldson LW, Petersen JM, Graves BJ, McIntosh LP. Structural coupling of the inhibitory regions flanking the ETS domain of murine Ets-1 Protein Science. 5: 296-309. PMID 8745408  1
1996 Jonsen MD, Petersen JM, Xu QP, Graves BJ. Characterization of the cooperative function of inhibitory sequences in Ets-1 Molecular and Cellular Biology. 16: 2065-2073. PMID 8628272  1
1996 Donaldson LW, Petersen JM, Graves BJ, McIntosh LP. Solution structure of the ETS domain from murine Ets-1: A winged helix-turn-helix DNA binding motif Embo Journal. 15: 125-134. PMID 8598195  1
1995 Wawrzynow A, Wojtkowiak D, Marszalek J, Banecki B, Jonsen M, Graves B, Georgopoulos C, Zylicz M. The ClpX heat-shock protein of Escherichia coli, the ATP-dependent substrate specificity component of the ClpP-ClpX protease, is a novel molecular chaperone Embo Journal. 14: 1867-1877. PMID 7743994  1
1995 Sun W, Graves BJ, Speck NA. Transactivation of the Moloney murine leukemia virus and T-cell receptor β-chain enhancers by cbf and ets requires intact binding sites for both proteins Journal of Virology. 69: 4941-4949. PMID 7609063  1
1994 Donaldson LW, Petersen JM, Graves BJ, McIntosh LP. Secondary structure of the ETS domain places murine Ets-1 in the superfamily of winged helix-turn-helix DNA-binding proteins Biochemistry. 33: 13509-13516. PMID 7947760  1
1994 Gunther CV, Graves BJ. Identification of ETS domain proteins in murine T lymphocytes that interact with the Moloney murine leukemia virus enhancer Molecular and Cellular Biology. 14: 7569-7580. PMID 7935472  1
1993 Nelsen B, Tian G, Erman B, Gregoire J, Maki R, Graves B, Sen R. Regulation of lymphoid-specific immunoglobulin mu heavy chain gene enhancer by ETS-domain proteins. Science (New York, N.Y.). 261: 82-6. PMID 8316859  1
1992 Nye JA, Petersen JM, Gunther CV, Jonsen MD, Graves BJ. Interaction of murine ets-1 with GGA-binding sites establishes the ETS domain as a new DNA-binding motif. Genes & Development. 6: 975-90. PMID 1592264  1
1990 Karim FD, Urness LD, Thummel CS, Klemsz MJ, McKercher SR, Celada A, Van Beveren C, Maki RA, Gunther CV, Nye JA. The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequence. Genes & Development. 4: 1451-3. PMID 2253872  1
1990 Gunther CV, Nye JA, Bryner RS, Graves BJ. Sequence-specific DNA binding of the proto-oncoprotein ets-1 defines a transcriptional activator sequence within the long terminal repeat of the Moloney murine sarcoma virus. Genes & Development. 4: 667-79. PMID 2163347  1
1990 Nye JA, Graves BJ. Alkylation interference identifies essential DNA contacts for sequence-specific binding of the eukaryotic transcription factor C/EBP. Proceedings of the National Academy of Sciences of the United States of America. 87: 3992-6. PMID 2160081  1
1988 Landschulz WH, Johnson PF, Adashi EY, Graves BJ, McKnight SL. Isolation of a recombinant copy of the gene encoding C/EBP. Genes & Development. 2: 786-800. PMID 2850264  1
1987 Johnson PF, Landschulz WH, Graves BJ, McKnight SL. Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses. Genes & Development. 1: 133-46. PMID 2824279  1
1986 Graves BJ, Johnson PF, McKnight SL. Homologous recognition of a promoter domain common to the MSV LTR and the HSV tk gene. Cell. 44: 565-76. PMID 3004739 DOI: 10.1016/0092-8674(86)90266-7  1
1985 Graves BJ, Eisenberg SP, Coen DM, McKnight SL. Alternate utilization of two regulatory domains within the Moloney murine sarcoma virus long terminal repeat. Molecular and Cellular Biology. 5: 1959-68. PMID 3018540  1
1985 Graves BJ, Eisenman RN, McKnight SL. Delineation of transcriptional control signals within the Moloney murine sarcoma virus long terminal repeat. Molecular and Cellular Biology. 5: 1948-58. PMID 3018539  1
1982 Graves BJ, Schubiger G. Cell cycle changes during growth and differentiation of imaginal leg discs in Drosophila melanogaster. Developmental Biology. 93: 104-10. PMID 6813162 DOI: 10.1016/0012-1606(82)90243-3  1
1981 Graves B, Schubiger G. Regional differences in the developing foreleg of Drosophila melanogaster. Developmental Biology. 85: 334-43. PMID 6790317 DOI: 10.1016/0012-1606(81)90265-7  1
1981 Riddiford LM, Chen AC, Graves BJ, Curtis AT. RNA and protein synthesis during the change to pupal commitment of Manduca sexta epidermis Insect Biochemistry. 11: 121-127. DOI: 10.1016/0020-1790(81)90050-0  1
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