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Christina Curtis, Ph.D. - Publications

Affiliations: 
2007 Biochemistry and Molecular Biology University of Southern California, Los Angeles, CA, United States 
 2014- Stanford University School of Medicine, Palo Alto, CA, United States 
Area:
Molecular Biology, Bioinformatics Biology
Website:
https://med.stanford.edu/curtislab/team.html
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78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sockell A, Wong W, Longwell S, Vu T, Karlsson K, Mokhtari D, Schaepe J, Lo YH, Cornelius V, Kuo C, Van Valen D, Curtis C, Fordyce PM. A microwell platform for high-throughput longitudinal phenotyping and selective retrieval of organoids. Cell Systems. 14: 764-776.e6. PMID 37734323 DOI: 10.1016/j.cels.2023.08.002  0.739
2023 Karlsson K, Przybilla MJ, Kotler E, Khan A, Xu H, Karagyozova K, Sockell A, Wong WH, Liu K, Mah A, Lo YH, Lu B, Houlahan KE, Ma Z, Suarez CJ, ... ... Curtis C, et al. Deterministic evolution and stringent selection during preneoplasia. Nature. 618: 383-393. PMID 37258665 DOI: 10.1038/s41586-023-06102-8  0.74
2021 Lo YH, Kolahi KS, Du Y, Chang CY, Krokhotin A, Nair A, Sobba WD, Karlsson K, Jones SJ, Longacre TA, Mah AT, Tercan B, Sockell A, Xu H, Seoane JA, ... ... Curtis C, et al. A CRISPR/Cas9-engineered ARID1A-deficient human gastric cancer organoid model reveals essential and non-essential modes of oncogenic transformation. Cancer Discovery. PMID 33451982 DOI: 10.1158/2159-8290.CD-20-1109  0.741
2020 Xiao Y, Thakkar KN, Zhao H, Broughton J, Li Y, Seoane JA, Diep AN, Metzner TJ, von Eyben R, Dill DL, Brooks JD, Curtis C, Leppert JT, Ye J, Peehl DM, et al. The mA RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America. PMID 32817424 DOI: 10.1073/Pnas.2000516117  0.358
2020 Zahir N, Sun R, Gallahan D, Gatenby RA, Curtis C. Characterizing the ecological and evolutionary dynamics of cancer. Nature Genetics. PMID 32719518 DOI: 10.1038/S41588-020-0668-4  0.394
2020 Hu Z, Li Z, Ma Z, Curtis C. Multi-cancer analysis of clonality and the timing of systemic spread in paired primary tumors and metastases. Nature Genetics. PMID 32424352 DOI: 10.1038/S41588-020-0628-Z  0.339
2020 Baslan T, Kendall J, Volyanskyy K, McNamara K, Cox H, D'Italia S, Ambrosio F, Riggs M, Rodgers L, Leotta A, Song J, Mao Y, Wu J, Shah R, Gularte-Mérida R, ... ... Curtis C, et al. Novel insights into breast cancer copy number genetic heterogeneity revealed by single-cell genome sequencing. Elife. 9. PMID 32401198 DOI: 10.7554/Elife.51480  0.375
2020 Han K, Pierce SE, Li A, Spees K, Anderson GR, Seoane JA, Lo YH, Dubreuil M, Olivas M, Kamber RA, Wainberg M, Kostyrko K, Kelly MR, Yousefi M, Simpkins SW, ... ... Curtis C, et al. CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities. Nature. 580: 136-141. PMID 32238925 DOI: 10.1038/S41586-020-2099-X  0.318
2020 Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, Zhou Y, Liu L, Vanharanta S, Graves EE, Rankin EB, Curtis C, Massague J, Rabinowitz JD, Thompson CB, et al. Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Molecular Cancer Research : McR. PMID 31941752 DOI: 10.1158/1541-7786.Mcr-19-0606  0.361
2020 Baslan T, Kendall J, Volyanskyy K, McNamara K, Cox H, D'Italia S, Ambrosio F, Riggs M, Rodgers L, Leotta A, Song J, Mao Y, Wu J, Shah R, Gularte-Mérida R, ... ... Curtis C, et al. Author response: Novel insights into breast cancer copy number genetic heterogeneity revealed by single-cell genome sequencing Elife. DOI: 10.7554/Elife.51480.Sa2  0.341
2020 Caswell-Jin JL, McNamara KL, Dering J, Chen H, Dichmann R, Perez A, Patel R, Kotler E, Zoeller JJ, Brugge JS, Press MF, Slamon DJ, Curtis C, Hurvitz SA. Abstract P4-07-01: Tumor expression and microenvironment in HER2-positive breast cancer before and on HER2-targeted therapy: Analysis of microarray expression data from the TRIO-US B07 trial Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P4-07-01  0.367
2020 Flowers B, Xu H, Hanson K, Curtis C, Vogel H, Wood L, Attardi LD. Abstract IA14: Deconstructing the origins of PDAC development Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-Ia14  0.391
2020 Li AM, Ducker GS, Li Y, Seoane JA, Xiao Y, Melemenidis S, Zhou Y, Liu L, Vanharanta S, Graves EE, Rankin EB, Curtis C, Massague J, Rabinowitz JD, Thompson CB, et al. Abstract 5713: Reprogramming of serine metabolism during breast cancer progression Cancer Research. 80: 5713-5713. DOI: 10.1158/1538-7445.Am2020-5713  0.376
2020 Liu M, Oxnard G, Klein E, Swanton C, Seiden M, Cummings SR, Absalan F, Alexander G, Allen B, Amini H, Aravanis AM, Bagaria S, Bazargan L, Beausang JF, Berman J, ... ... Curtis C, et al. Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNA Annals of Oncology. 31: 745-759. DOI: 10.1016/J.Annonc.2020.02.011  0.32
2019 Seoane JA, Kirkland JG, Caswell-Jin JL, Crabtree GR, Curtis C. Chromatin regulators mediate anthracycline sensitivity in breast cancer. Nature Medicine. PMID 31700186 DOI: 10.1038/S41591-019-0638-5  0.349
2019 Hu Z, Ding J, Ma Z, Sun R, Seoane JA, Scott Shaffer J, Suarez CJ, Berghoff AS, Cremolini C, Falcone A, Loupakis F, Birner P, Preusser M, Lenz HJ, Curtis C. Quantitative evidence for early metastatic seeding in colorectal cancer. Nature Genetics. PMID 31209394 DOI: 10.1038/S41588-019-0423-X  0.378
2019 Rueda OM, Sammut SJ, Seoane JA, Chin SF, Caswell-Jin JL, Callari M, Batra R, Pereira B, Bruna A, Ali HR, Provenzano E, Liu B, Parisien M, Gillett C, McKinney S, ... ... Curtis C, et al. Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups. Nature. PMID 30867590 DOI: 10.1038/S41586-019-1007-8  0.356
2019 Caswell-Jin JL, McNamara K, Reiter JG, Sun R, Hu Z, Ma Z, Ding J, Suarez CJ, Tilk S, Raghavendra A, Forte V, Chin SF, Bardwell H, Provenzano E, Caldas C, ... ... Curtis C, et al. Clonal replacement and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy. Nature Communications. 10: 657. PMID 30737380 DOI: 10.1038/S41467-019-08593-4  0.32
2019 Caswell-Jin J, McNamara K, Reiter J, Sun R, Hu Z, Ma Z, Suarez C, Tilk S, Raghavendra A, Forte V, Chin S, Bardwell H, Provenzano E, Caldas C, Lang J, ... ... Curtis C, et al. Abstract P3-06-01: Clonal evolution and heterogeneity in breast tumors treated with neoadjuvant HER2-targeted therapy Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P3-06-01  0.345
2019 Curtis C, Rueda O, Sammut S, Chin S, Caswell-Jin J, Seoane J, Callari M, Batra R, Pereira B, Bruna A, Ali H, Provenzano E, Liu B, Parisien M, Gillett C, et al. Abstract GS3-06: Dynamics of breast cancer relapse reveal molecularly defined late recurring ER-positive subgroups: Results from the METABRIC study Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Gs3-06  0.346
2019 Seoane JA, Kirkland JG, Caswell-Jin JL, Crabtree GR, Curtis C. Abstract 2108: Chromatin state as a mechanism of anthracycline response in breast cancer Cancer Research. 79: 2108-2108. DOI: 10.1158/1538-7445.Sabcs18-2108  0.372
2019 Flowers B, Xu H, Hanson K, Curtis C, Vogel H, Wood LD, Attardi LD. Abstract I15: Deciphering the origins of PDAC development Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-I15  0.394
2019 Flowers BM, Xu H, Hanson K, Curtis C, Vogel H, Wood LD, Attardi LD. Abstract A15: Elucidating the role of p53 in the cellular origins of pancreatic cancer development Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-A15  0.373
2018 Press MF, Seoane JA, Curtis C, Quinaux E, Guzman R, Sauter G, Eiermann W, Mackey JR, Robert N, Pienkowski T, Crown J, Martin M, Valero V, Bee V, Ma Y, et al. Assessment of ERBB2/HER2 Status in HER2-Equivocal Breast Cancers by FISH and 2013/2014 ASCO-CAP Guidelines. Jama Oncology. PMID 30520947 DOI: 10.1001/Jamaoncol.2018.6012  0.34
2018 Corces MR, Granja JM, Shams S, Louie BH, Seoane JA, Zhou W, Silva TC, Groeneveld C, Wong CK, Cho SW, Satpathy AT, Mumbach MR, Hoadley KA, Robertson AG, Sheffield NC, ... ... Curtis C, et al. The chromatin accessibility landscape of primary human cancers. Science (New York, N.Y.). 362. PMID 30361341 DOI: 10.1126/Science.Aav1898  0.379
2018 Probert C, Curtis C. A role for chromatin regulatory dynamics in breast cancer evolution. Nature Medicine. PMID 30177822 DOI: 10.1038/S41591-018-0182-8  0.33
2018 Pogrebniak KL, Curtis CN. Harnessing Tumor Evolution to Circumvent Resistance. Trends in Genetics : Tig. PMID 29903534 DOI: 10.1016/J.Tig.2018.05.007  0.314
2018 Williams MJ, Werner B, Heide T, Curtis C, Barnes CP, Sottoriva A, Graham TA. Quantification of subclonal selection in cancer from bulk sequencing data. Nature Genetics. PMID 29808029 DOI: 10.1038/S41588-018-0128-6  0.39
2018 Cho SW, Xu J, Sun R, Mumbach MR, Carter AC, Chen YG, Yost KE, Kim J, He J, Nevins SA, Chin SF, Caldas C, Liu SJ, Horlbeck MA, Lim DA, ... ... Curtis C, et al. Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. Cell. PMID 29731168 DOI: 10.1016/J.Cell.2018.03.068  0.389
2018 Kuo CJ, Curtis C. Organoids reveal cancer dynamics. Nature. 556: 441-442. PMID 29686366 DOI: 10.1038/D41586-018-03841-X  0.301
2018 Rogers ZN, McFarland CD, Winters IP, Seoane JA, Brady JJ, Yoon S, Curtis C, Petrov DA, Winslow MM. Mapping the in vivo fitness landscape of lung adenocarcinoma tumor suppression in mice. Nature Genetics. PMID 29610476 DOI: 10.1038/S41588-018-0083-2  0.311
2018 Shukla N, Salahudeen AA, de la O S, Hart DJ, Taylor G, Zhu J, Yuki K, Seoane J, Ma Z, Ding J, Han K, Morgens D, Bassik M, Curtis C, Kuo CJ. Identification and validation of a novel drug target in an organoid model of esophageal cancer. Journal of Clinical Oncology. 36: 46-46. DOI: 10.1200/Jco.2018.36.4_Suppl.46  0.332
2018 Liu MC, Maddala T, Aravanis A, Hubbell E, Beausang JF, Filippova D, Gross S, Jamshidi A, Kurtzman K, Shen L, Valouev A, Venn O, Zhang N, Smith DA, Couch F, ... Curtis C, et al. Breast cancer cell-free DNA (cfDNA) profiles reflect underlying tumor biology: The Circulating Cell-Free Genome Atlas (CCGA) study. Journal of Clinical Oncology. 36: 536-536. DOI: 10.1200/Jco.2018.36.15_Suppl.536  0.347
2018 Aravanis AA, Oxnard GR, Maddala T, Hubbell E, Venn O, Jamshidi A, Shen L, Amini H, Beausang JA, Betts C, Civello D, Davydov K, Fazullina S, Filippova D, Gnerre S, ... ... Curtis C, et al. Abstract LB-343: Development of plasma cell-free DNA (cfDNA) assays for early cancer detection: first insights from the Circulating Cell-Free Genome Atlas Study (CCGA) Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-343  0.379
2017 Mello SS, Valente LJ, Raj N, Seoane JA, Flowers BM, McClendon J, Bieging-Rolett KT, Lee J, Ivanochko D, Kozak MM, Chang DT, Longacre TA, Koong AC, Arrowsmith CH, Kim SK, ... ... Curtis C, et al. A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer. Cancer Cell. 32: 460-473.e6. PMID 29017057 DOI: 10.1016/J.Ccell.2017.09.007  0.354
2017 Sun R, Hu Z, Curtis C. Big Bang Tumor Growth and Clonal Evolution. Cold Spring Harbor Perspectives in Medicine. PMID 28710260 DOI: 10.1101/Cshperspect.A028381  0.337
2017 Sun R, Hu Z, Sottoriva A, Graham TA, Harpak A, Ma Z, Fischer JM, Shibata D, Curtis C. Between-region genetic divergence reflects the mode and tempo of tumor evolution. Nature Genetics. PMID 28581503 DOI: 10.1038/Ng.3891  0.316
2017 Hu Z, Sun R, Curtis C. A population genetics perspective on the determinants of intra-tumor heterogeneity. Biochimica Et Biophysica Acta. PMID 28274726 DOI: 10.1016/J.Bbcan.2017.03.001  0.363
2017 Zhao J, Salomon MP, Shibata D, Curtis C, Siegmund K, Marjoram P. Early mutation bursts in colorectal tumors. Plos One. 12: e0172516. PMID 28257429 DOI: 10.1371/Journal.Pone.0172516  0.347
2017 Gendelman R, Xing H, Mirzoeva OK, Sarde P, Curtis C, Feiler H, McDonagh P, Gray JW, Khalil I, Korn WM. Bayesian network inference modeling identifies TRIB1 as a novel regulator of cell cycle progression and survival in cancer cells. Cancer Research. PMID 28087598 DOI: 10.1158/0008-5472.Can-16-0512  0.352
2016 Hu Z, Mao JH, Curtis C, Huang G, Gu S, Heiser L, Lenburg ME, Korkola JE, Bayani N, Samarajiwa S, Seoane JA, A Dane M, Esch A, Feiler HS, Wang NJ, et al. Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer. Breast Cancer Research : Bcr. 18: 70. PMID 27368372 DOI: 10.1186/S13058-016-0728-Y  0.343
2016 Curtis C, Landis GN, Folk D, Wehr NB, Hoe N, Waskar M, Abdueva D, Skvortsov D, Ford D, Luu A, Badrinath A, Levine RL, Bradley TJ, Tavaré S, Tower J. Erratum to: Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes. Genome Biology. 17: 93. PMID 27154433 DOI: 10.1186/s13059-016-0959-3  0.721
2016 Afghahi A, Rigdon J, Purington N, Desai M, Pierson E, Mathur M, Thompson CA, Curtis C, West RB, Horst KC, Gomez SL, Ford JM, Sledge GW, Kurian AW. Higher peripheral lymphocyte count to predict survival in triple-negative breast cancer (TNBC). Journal of Clinical Oncology. 34: 1010-1010. DOI: 10.1200/Jco.2016.34.15_Suppl.1010  0.313
2015 Sottoriva A, Kang H, Ma Z, Graham TA, Salomon MP, Zhao J, Marjoram P, Siegmund K, Press MF, Shibata D, Curtis C. A Big Bang model of human colorectal tumor growth. Nature Genetics. 47: 209-16. PMID 25665006 DOI: 10.1038/Ng.3214  0.341
2015 Curtis C. Genomic profiling of breast cancers. Current Opinion in Obstetrics & Gynecology. 27: 34-9. PMID 25502431 DOI: 10.1097/Gco.0000000000000145  0.316
2015 Piccirillo SG, Spiteri I, Sottoriva A, Touloumis A, Ber S, Price SJ, Heywood R, Francis NJ, Howarth KD, Collins VP, Venkitaraman AR, Curtis C, Marioni JC, Tavaré S, Watts C. Contributions to drug resistance in glioblastoma derived from malignant cells in the sub-ependymal zone. Cancer Research. 75: 194-202. PMID 25406193 DOI: 10.1158/0008-5472.Can-13-3131  0.311
2015 Vollan HK, Rueda OM, Chin SF, Curtis C, Turashvili G, Shah S, Lingjærde OC, Yuan Y, Ng CK, Dunning MJ, Dicks E, Provenzano E, Sammut S, McKinney S, Ellis IO, et al. A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer. Molecular Oncology. 9: 115-27. PMID 25169931 DOI: 10.1016/J.Molonc.2014.07.019  0.342
2015 Sottoriva A, Kang H, Ma Z, Graham TA, Salomon M, Zhao J, Marjoram P, Siegmund K, Press MF, Shibata D, Curtis C. Abstract B2-23: A Big Bang model of human colorectal tumor growth Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-B2-23  0.348
2014 Ali HR, Rueda OM, Chin SF, Curtis C, Dunning MJ, Aparicio SA, Caldas C. Genome-driven integrated classification of breast cancer validated in over 7,500 samples. Genome Biology. 15: 431. PMID 25164602 DOI: 10.1186/S13059-014-0431-1  0.344
2014 Viré E, Curtis C, Davalos V, Git A, Robson S, Villanueva A, Vidal A, Barbieri I, Aparicio S, Esteller M, Caldas C, Kouzarides T. The breast cancer oncogene EMSY represses transcription of antimetastatic microRNA miR-31. Molecular Cell. 53: 806-18. PMID 24582497 DOI: 10.1016/J.Molcel.2014.01.029  0.306
2014 Piccirillo SGM, Spiteri I, Sottoriva A, Touloumis A, Curtis C, Marioni J, Tavaer S, Watts C. O11 * TRANSCRIPTIONAL PROFILING OF DISTINCT COMPARTMENTS IN HUMAN GLIOBLASTOMA REVEALS KEY DYSREGULATED PATHWAYS Neuro-Oncology. 16: vi14-vi15. DOI: 10.1093/Neuonc/Nou250.11  0.322
2014 Watts C, Piccirillo S, Spiteri I, Sottoriva A, Touloumis A, Marioni J, Curtis C, Tavare S. COMPLEX EVOLUTIONARY DYNAMICS GENERATES GENETIC DIVERSITY AND INTRA-TUMOR HETEROGENEITY IN INDIVIDUAL PATIENTS WITH GLIOBLASTOMA Neuro-Oncology. 16: iii7-iii7. DOI: 10.1093/Neuonc/Nou206.23  0.562
2014 Piccirillo SGM, Spiteri I, Sottoriva A, Touloumis A, Collins P, Curtis C, Marioni J, Tavare' S, Watts C. O4.05 * GENETIC DIVERSITY AND INTRA-TUMOR HETEROGENEITY IN HUMAN GLIOBLASTOMA Neuro-Oncology. 16: ii8-ii8. DOI: 10.1093/Neuonc/Nou174.26  0.356
2013 Chen GK, Chang X, Curtis C, Wang K. Precise inference of copy number alterations in tumor samples from SNP arrays. Bioinformatics (Oxford, England). 29: 2964-70. PMID 24021380 DOI: 10.1093/Bioinformatics/Btt521  0.307
2013 Bilal E, Dutkowski J, Guinney J, Jang IS, Logsdon BA, Pandey G, Sauerwine BA, Shimoni Y, Moen Vollan HK, Mecham BH, Rueda OM, Tost J, Curtis C, Alvarez MJ, Kristensen VN, et al. Improving breast cancer survival analysis through competition-based multidimensional modeling. Plos Computational Biology. 9: e1003047. PMID 23671412 DOI: 10.1371/Journal.Pcbi.1003047  0.347
2013 Margolin AA, Bilal E, Huang E, Norman TC, Ottestad L, Mecham BH, Sauerwine B, Kellen MR, Mangravite LM, Furia MD, Vollan HK, Rueda OM, Guinney J, Deflaux NA, Hoff B, ... ... Curtis C, et al. Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer. Science Translational Medicine. 5: 181re1. PMID 23596205 DOI: 10.1126/Scitranslmed.3006112  0.349
2013 Sottoriva A, Spiteri I, Piccirillo SG, Touloumis A, Collins VP, Marioni JC, Curtis C, Watts C, Tavaré S. Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. Proceedings of the National Academy of Sciences of the United States of America. 110: 4009-14. PMID 23412337 DOI: 10.1073/Pnas.1219747110  0.38
2013 Sottoriva A, Spiteri I, Shibata D, Curtis C, Tavaré S. Single-molecule genomic data delineate patient-specific tumor profiles and cancer stem cell organization. Cancer Research. 73: 41-9. PMID 23090114 DOI: 10.1158/0008-5472.Can-12-2273  0.584
2013 Rueda OM, Ali RH, Curtis C, Chin S, Bruna A, Russell R, Pereira B, Aparicio S, Caldas C. Abstract B020: A copy number and expression based classifier for breast cancer tumors Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-B020  0.374
2013 Sottoriva A, Ma Z, Kang H, Curtis C. Abstract SY36-01: Exploiting intra-tumor heterogeneity through agent-based models of tumor growth to infer properties of human malignancies. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Sy36-01  0.373
2013 Piccirillo SGM, Spiteri I, Sottoriva A, Touloumis A, Ber S, Price SJ, Heywood R, Francis N, Collins VP, Venkitaraman AR, Curtis C, Marioni JC, Tavare S, Watts C. Abstract 5016: The human sub-ependymal zone harbors glioblastoma precursors and represents a distinct therapeutic target. Cancer Research. 73: 5016-5016. DOI: 10.1158/1538-7445.Am2013-5016  0.582
2013 Adachi K, Sasaki H, Nagahisa S, Yoshida K, Hattori N, Nishiyama Y, Kawase T, Hasegawa M, Abe M, Hirose Y, Alentorn A, Marie Y, Poggioli S, Alshehhi H, Boisselier B, ... ... Curtis C, et al. OMICS AND PROGNSTIC MARKERS Neuro-Oncology. 15: iii136-iii155. DOI: 10.1093/Neuonc/Not183  0.485
2012 Yuan Y, Failmezger H, Rueda OM, Ali HR, Gräf S, Chin SF, Schwarz RF, Curtis C, Dunning MJ, Bardwell H, Johnson N, Doyle S, Turashvili G, Provenzano E, Aparicio S, et al. Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling. Science Translational Medicine. 4: 157ra143. PMID 23100629 DOI: 10.1126/Scitranslmed.3004330  0.386
2012 Lynch AG, Chin SF, Dunning MJ, Caldas C, Tavaré S, Curtis C. Calling sample mix-ups in cancer population studies. Plos One. 7: e41815. PMID 22912679 DOI: 10.1371/Journal.Pone.0041815  0.307
2012 Curtis C, Shah SP, Chin SF, Turashvili G, Rueda OM, Dunning MJ, Speed D, Lynch AG, Samarajiwa S, Yuan Y, Gräf S, Ha G, Haffari G, Bashashati A, Russell R, et al. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature. 486: 346-52. PMID 22522925 DOI: 10.1038/Nature10983  0.382
2012 Shah SP, Roth A, Goya R, Oloumi A, Ha G, Zhao Y, Turashvili G, Ding J, Tse K, Haffari G, Bashashati A, Prentice LM, Khattra J, Burleigh A, Yap D, ... ... Curtis C, et al. The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature. 486: 395-9. PMID 22495314 DOI: 10.1038/Nature10933  0.351
2012 Yuan Y, Curtis C, Caldas C, Markowetz F. A sparse regulatory network of copy-number driven gene expression reveals putative breast cancer oncogenes. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 9: 947-54. PMID 21788678 DOI: 10.1109/Tcbb.2011.105  0.406
2011 Yuan Y, Rueda OM, Curtis C, Markowetz F. Penalized regression elucidates aberration hotspots mediating subtype-specific transcriptional responses in breast cancer. Bioinformatics (Oxford, England). 27: 2679-85. PMID 21804112 DOI: 10.1093/Bioinformatics/Btr450  0.422
2011 Holland DG, Burleigh A, Git A, Goldgraben MA, Perez-Mancera PA, Chin SF, Hurtado A, Bruna A, Ali HR, Greenwood W, Dunning MJ, Samarajiwa S, Menon S, Rueda OM, Lynch AG, ... ... Curtis C, et al. ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium. Embo Molecular Medicine. 3: 167-80. PMID 21337521 DOI: 10.1002/Emmm.201100122  0.351
2010 Dunning MJ, Curtis C, Barbosa-Morais NL, Caldas C, Tavaré S, Lynch AG. The importance of platform annotation in interpreting microarray data. The Lancet. Oncology. 11: 717. PMID 20688273 DOI: 10.1016/S1470-2045(10)70115-7  0.514
2010 Curtis C, Chin S, Shah S, Tavaré S, Aparicio S, Caldas C. 825 Towards a systems-level view of breast cancer through the joint analysis of multi-dimensional data European Journal of Cancer Supplements. 8: 208. DOI: 10.1016/S1359-6349(10)71621-9  0.478
2009 Waskar M, Landis GN, Shen J, Curtis C, Tozer K, Abdueva D, Skvortsov D, Tavaré S, Tower J. Drosophila melanogaster p53 has developmental stage-specific and sex-specific effects on adult life span indicative of sexual antagonistic pleiotropy. Aging. 1: 903-36. PMID 20157574  0.712
2009 Shen J, Curtis C, Tavaré S, Tower J. A screen of apoptosis and senescence regulatory genes for life span effects when over-expressed in Drosophila. Aging. 1: 191-211. PMID 20157509  0.502
2009 Curtis C, Lynch AG, Dunning MJ, Spiteri I, Marioni JC, Hadfield J, Chin SF, Brenton JD, Tavaré S, Caldas C. The pitfalls of platform comparison: DNA copy number array technologies assessed. Bmc Genomics. 10: 588. PMID 19995423 DOI: 10.1186/1471-2164-10-588  0.319
2009 Tiemann-Boege I, Curtis C, Shinde DN, Goodman DB, Tavaré S, Arnheim N. Product length, dye choice, and detection chemistry in the bead-emulsion amplification of millions of single DNA molecules in parallel. Analytical Chemistry. 81: 5770-6. PMID 19601653 DOI: 10.1021/Ac900633Y  0.613
2008 Tiemann-Boege I, Curtis C, Shibata D, Tavaré S. High-throughput analysis of methylation patterns to track cell divisions Gbm Annual Spring Meeting Mosbach 2008. 2008. DOI: 10.1240/sav_gbm_2008_m_002227  0.45
2007 Curtis C, Landis GN, Folk D, Wehr NB, Hoe N, Waskar M, Abdueva D, Skvortsov D, Ford D, Luu A, Badrinath A, Levine RL, Bradley TJ, Tavaré S, Tower J. Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes. Genome Biology. 8: R262. PMID 18067683 DOI: 10.1186/Gb-2007-8-12-R262  0.732
2007 Skvortsov D, Abdueva D, Curtis C, Schaub B, Tavaré S. Explaining differences in saturation levels for Affymetrix GeneChip arrays. Nucleic Acids Research. 35: 4154-63. PMID 17567617 DOI: 10.1093/Nar/Gkm348  0.717
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