Francisco Baralle - Related publications

University of Oxford, Oxford, United Kingdom 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Joynt AT, Evans TA, Pellicore MJ, Davis-Marcisak EF, Aksit MA, Eastman AC, Patel SU, Paul KC, Osorio DL, Bowling AD, Cotton CU, Raraigh KS, West NE, Merlo CA, Cutting GR, et al. Evaluation of both exonic and intronic variants for effects on RNA splicing allows for accurate assessment of the effectiveness of precision therapies. Plos Genetics. 16: e1009100. PMID 33085659 DOI: 10.1371/journal.pgen.1009100   
2020 Koterniak B, Pilaka PP, Gracida X, Schneider LM, Pritišanac I, Zhang Y, Calarco JA. Global regulatory features of alternative splicing across tissues and within the nervous system of . Genome Research. PMID 33127752 DOI: 10.1101/gr.267328.120   
2020 Hooper JE, Jones KL, Smith FJ, Williams T, Li H. An Alternative Splicing Program for Mouse Craniofacial Development. Frontiers in Physiology. 11: 1099. PMID 33013468 DOI: 10.3389/fphys.2020.01099   
2020 Alvarez MEV, Chivers M, Borovska I, Monger S, Giannoulatou E, Kralovicova J, Vorechovsky I. Transposon clusters as substrates for aberrant splice-site activation. Rna Biology. 1-14. PMID 32965162 DOI: 10.1080/15476286.2020.1805909   
2020 Baeza-Centurion P, Minana B, Valcarcel J, Lehner B. Mutations primarily alter the inclusion of alternatively spliced exons. Elife. 9. PMID 33112234 DOI: 10.7554/eLife.59959   
2020 Hershberger CE, Daniels NJ, Padgett RA. Spliceosomal factor mutations and mis-splicing in MDS. Best Practice & Research. Clinical Haematology. 33: 101199. PMID 33038983 DOI: 10.1016/j.beha.2020.101199   
2020 Petasny M, Bentata M, Pawellek A, Baker M, Kay G, Salton M. Splicing to Keep Cycling: The Importance of Pre-mRNA Splicing during the Cell Cycle. Trends in Genetics : Tig. PMID 32950269 DOI: 10.1016/j.tig.2020.08.013   
2020 Cao S, Zhou DC, Oh C, Jayasinghe RG, Zhao Y, Yoon CJ, Wyczalkowski MA, Bailey MH, Tsou T, Gao Q, Malone A, Reynolds S, Shmulevich I, Wendl MC, Chen F, et al. Discovery of driver non-coding splice-site-creating mutations in cancer. Nature Communications. 11: 5573. PMID 33149122 DOI: 10.1038/s41467-020-19307-6   
2020 Hong EM, Ingemarsdotter CK, Lever AML. Therapeutic applications of trans-splicing. British Medical Bulletin. PMID 33010155 DOI: 10.1093/bmb/ldaa028   
2020 Rodriguez JM, Pozo F, di Domenico T, Vazquez J, Tress ML. An analysis of tissue-specific alternative splicing at the protein level. Plos Computational Biology. 16: e1008287. PMID 33017396 DOI: 10.1371/journal.pcbi.1008287   
2020 Henson HE, Taylor MR. A Zebrafish Mutant Results in Developmental Defects in the Central Nervous System. Cells. 9. PMID 33105605 DOI: 10.3390/cells9112340   
2020 Zeng L, Li Z, Pan L, Li H, Wu J, Yuan X, Li Z, Liang D, Wu L. Novel GZF1 pathogenic variants identified in two Chinese patients with Larsen syndrome. Clinical Genetics. PMID 33009817 DOI: 10.1111/cge.13856   
2020 Mohanta A, Chakrabarti K. Dbr1 functions in mRNA processing, intron turnover and human diseases. Biochimie. PMID 33038423 DOI: 10.1016/j.biochi.2020.10.003   
2020 Sun L, Zhang F, Guo F, Liu F, Kulsuptrakul J, Puschnik A, Gao M, Rijnbrand R, Sofia M, Block T, Zhou T. The dihydroquinolizinone compound RG7834 inhibits the polyadenylase function of PAPD5/7 and accelerates the degradation of matured HBV surface protein mRNA. Antimicrobial Agents and Chemotherapy. PMID 33046485 DOI: 10.1128/AAC.00640-20   
2020 Wu D, Zang YY, Shi YY, Ye C, Cai WM, Tang XH, Zhao L, Liu Y, Gan Z, Chen GQ, Xu Y, Yang JJ, Shi YS. Distant Coupling between RNA Editing and Alternative Splicing of the Osmosensitive Cation Channel Tmem63b. The Journal of Biological Chemistry. PMID 33100268 DOI: 10.1074/jbc.RA120.016049   
2020 Larsen K, Bæk R, Sahin C, Kjær L, Christiansen G, Nielsen J, Farajzadeh L, Otzen DE. Molecular characteristics of porcine alpha-synuclein splicing variants. Biochimie. PMID 33152422 DOI: 10.1016/j.biochi.2020.10.019   
2020 Maji D, Glasser E, Henderson S, Galardi J, Pulvino MJ, Jenkins JL, Kielkopf CL. Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing. The Journal of Biological Chemistry. PMID 33020180 DOI: 10.1074/jbc.RA120.015339   
2020 Li D, Aung-Htut MT, Ham KA, Fletcher S, Wilton SD. A Splice Intervention Therapy for Autosomal Recessive Juvenile Parkinson's Disease Arising from Parkin Mutations. International Journal of Molecular Sciences. 21. PMID 33019779 DOI: 10.3390/ijms21197282   
2020 Elhasnaoui J, Miano V, Ferrero G, Doria E, Leon AE, Fabricio ASC, Annaratone L, Castellano I, Sapino A, De Bortoli M. DSCAM-AS1-Driven Proliferation of Breast Cancer Cells Involves Regulation of Alternative Exon Splicing and 3'-End Usage. Cancers. 12. PMID 32503257 DOI: 10.3390/cancers12061453   
2020 Patsali P, Papasavva P, Christou S, Sitarou M, Antoniou MN, Lederer CW, Kleanthous M. Relative and Absolute Quantification of Aberrant and Normal Splice Variants in β-Thalassemia. International Journal of Molecular Sciences. 21. PMID 32933098 DOI: 10.3390/ijms21186671   
2020 Choi N, Liu Y, Oh J, Ha J, Ghigna C, Zheng X, Shen H. Relative strength of 5' splice-site strength defines functions of SRSF2 and SRSF6 in alternative splicing of Bcl-x pre-mRNA. Bmb Reports. PMID 33050987   
2020 Luo L, Kang H, Li X, Ness SA, Stidley CA. Two-step mixed model approach to analyzing differential alternative RNA splicing. Plos One. 15: e0232646. PMID 33035235 DOI: 10.1371/journal.pone.0232646   
2020 Islam F, Pillai S, Gopalan V, Lam AK. Identification of Novel Mutations and Expressions of in Phaeochromocytomas and Paragangliomas. Genes. 11. PMID 33114456 DOI: 10.3390/genes11111254   
2020 Flach J, Jann JC, Knaflic A, Riabov V, Streuer A, Altrock E, Xu Q, Schmitt N, Obländer J, Nowak V, Danner J, Mehralivand A, Hofmann F, Palme I, Jawhar A, et al. Replication stress signaling is a therapeutic target in myelodysplastic syndromes with splicing factor mutations. Haematologica. PMID 33054116 DOI: 10.3324/haematol.2020.254193   
2020 Li X, He X, Wang J, Wang D, Cong P, Zhu A, Chen W. The Regulation of Exosome-Derived miRNA on Heterogeneity of Macrophages in Atherosclerotic Plaques. Frontiers in Immunology. 11: 2175. PMID 33013913 DOI: 10.3389/fimmu.2020.02175   
2020 Rambout X, Maquat LE. NCBP3: A Multifaceted Adaptive Regulator of Gene Expression. Trends in Biochemical Sciences. PMID 33032857 DOI: 10.1016/j.tibs.2020.09.003   
2020 Ham KA, Aung-Htut MT, Fletcher S, Wilton SD. Nonsequential Splicing Events Alter Antisense-Mediated Exon Skipping Outcome in . International Journal of Molecular Sciences. 21. PMID 33081018 DOI: 10.3390/ijms21207705   
2020 Carrasco J, Rauer M, Hummel B, Grzejda D, Alfonso-Gonzalez C, Lee Y, Wang Q, Puchalska M, Mittler G, Hilgers V. ELAV and FNE Determine Neuronal Transcript Signatures through EXon-Activated Rescue. Molecular Cell. 80: 156-163.e6. PMID 33007255 DOI: 10.1016/j.molcel.2020.09.011   
2020 Carrasco J, Rauer M, Hummel B, Grzejda D, Alfonso-Gonzalez C, Lee Y, Wang Q, Puchalska M, Mittler G, Hilgers V. ELAV and FNE Determine Neuronal Transcript Signatures through EXon-Activated Rescue. Molecular Cell. 80: 156-163.e6. PMID 33007255 DOI: 10.1016/j.molcel.2020.09.011   
2020 Oikonomou P, Salatino R, Tavazoie S. In vivo mRNA display enables large-scale proteomics by next generation sequencing. Proceedings of the National Academy of Sciences of the United States of America. PMID 33037152 DOI: 10.1073/pnas.2002650117   
2020 Miro J, Bougé AL, Murauer E, Beyne E, Da Cunha D, Claustres M, Koenig M, Tuffery-Giraud S. First Identification of RNA-Binding Proteins That Regulate Alternative Exons in the Dystrophin Gene. International Journal of Molecular Sciences. 21. PMID 33096920 DOI: 10.3390/ijms21207803   
2020 Anderson AJ, Culver HR, Prieto TR, Martinez PJ, Sinha J, Bryant SJ, Bowman CN. Messenger RNA enrichment using synthetic oligo(T) click nucleic acids. Chemical Communications (Cambridge, England). PMID 33094748 DOI: 10.1039/d0cc05815g   
2020 Kinkar E, Kinkar A, Saleh M. AU richness within the 5' coding region of the heat-stable enterotoxin b mRNA affects toxin secretion. Heliyon. 6: e05330. PMID 33163652 DOI: 10.1016/j.heliyon.2020.e05330   
2020 Chhatbar K, Cholewa-Waclaw J, Shah R, Bird A, Sanguinetti G. Quantitative analysis questions the role of MeCP2 as a global regulator of alternative splicing. Plos Genetics. 16: e1009087. PMID 33048927 DOI: 10.1371/journal.pgen.1009087   
2020 Palazzo AF, Kang YM. GC-content biases in protein-coding genes act as an "mRNA identity" feature for nuclear export. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e2000197. PMID 33165929 DOI: 10.1002/bies.202000197   
2020 Rao S, Hoskins I, Garcia PD, Tonn T, Ozadam H, Cenik ES, Cenik C. Genes with 5' terminal oligopyrimidine tracts preferentially escape global suppression of translation by the SARS-CoV-2 NSP1 protein. Biorxiv : the Preprint Server For Biology. PMID 32995776 DOI: 10.1101/2020.09.13.295493   
2020 Fahim A, Afrin F, Wen G, Ananvoranich S. Characterization of natural antisense transcripts arisen from the locus encoding Toxoplasma gondii ubiquitin-like protease. Molecular and Biochemical Parasitology. 240: 111334. PMID 33011210 DOI: 10.1016/j.molbiopara.2020.111334   
2020 Zhang C, Han B, Xu T, Li D. The biological function and potential mechanism of long non-coding RNAs in cardiovascular disease. Journal of Cellular and Molecular Medicine. PMID 33052009 DOI: 10.1111/jcmm.15968   
2020 Zhang C, Han B, Xu T, Li D. The biological function and potential mechanism of long non-coding RNAs in cardiovascular disease. Journal of Cellular and Molecular Medicine. PMID 33052009 DOI: 10.1111/jcmm.15968   
2020 Saaoud F, Drummer I V C, Shao Y, Sun Y, Lu Y, Xu K, Ni D, Jiang X, Wang H, Yang X. Circular RNAs are a novel type of non-coding RNAs in ROS regulation, cardiovascular metabolic inflammations and cancers. Pharmacology & Therapeutics. 107715. PMID 33141028 DOI: 10.1016/j.pharmthera.2020.107715   
2020 Guo G, Shi X, Wang H, Ye L, Tong X, Yan K, Ding N, Chen C, Zhang H, Xue X. Epitranscriptomic N4-Acetylcytidine Profiling in CD4 T Cells of Systemic Lupus Erythematosus. Frontiers in Cell and Developmental Biology. 8: 842. PMID 32984334 DOI: 10.3389/fcell.2020.00842   
2020 Ando S, Suzuki S, Okubo S, Ohuchi K, Takahashi K, Nakamura S, Shimazawa M, Fuji K, Hara H. Discovery of a CNS penetrant small molecule SMN2 splicing modulator with improved tolerability for spinal muscular atrophy. Scientific Reports. 10: 17472. PMID 33060681 DOI: 10.1038/s41598-020-74346-9   
2020 Bresson S, Shchepachev V, Spanos C, Turowski TW, Rappsilber J, Tollervey D. Stress-Induced Translation Inhibition through Rapid Displacement of Scanning Initiation Factors. Molecular Cell. PMID 33053322 DOI: 10.1016/j.molcel.2020.09.021   
2020 Liu N, Dong X, Hu C, Zeng J, Wang J, Wang J, Wang HW, Belfort M. Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing. Nucleic Acids Research. PMID 33021674 DOI: 10.1093/nar/gkaa773   
2020 Vargas-Blanco DA, Shell SS. Regulation of mRNA Stability During Bacterial Stress Responses. Frontiers in Microbiology. 11: 2111. PMID 33013770 DOI: 10.3389/fmicb.2020.02111   
2020 Liu Y, Pan C, Kong D, Luo J, Zhang Z. A Survey of Regulatory Interactions Among RNA Binding Proteins and MicroRNAs in Cancer. Frontiers in Genetics. 11: 515094. PMID 33101370 DOI: 10.3389/fgene.2020.515094   
2020 Stepniak-Konieczna E, Konieczny P, Cywoniuk P, Dluzewska J, Sobczak K. AON-induced splice-switching and DMPK pre-mRNA degradation as potential therapeutic approaches for Myotonic Dystrophy type 1. Nucleic Acids Research. 48: 2531-2543. PMID 31965181 DOI: 10.1093/nar/gkaa007   
2020 Loughran G, Zhdanov AV, Mikhaylova MS, Rozov FN, Datskevich PN, Kovalchuk SI, Serebryakova MV, Kiniry SJ, Michel AM, O'Connor PBF, Papkovsky DB, Atkins JF, Baranov PV, Shatsky IN, Andreev DE. Unusually efficient CUG initiation of an overlapping reading frame in mRNA yields novel protein POLGARF. Proceedings of the National Academy of Sciences of the United States of America. 117: 24936-24946. PMID 32958672 DOI: 10.1073/pnas.2001433117   
2020 Li Z, Zhang Y, Bush SJ, Tang C, Chen L, Zhang D, Urrutia AO, Lin JW, Chen L. MeDAS: a Metazoan Developmental Alternative Splicing database. Nucleic Acids Research. PMID 33084905 DOI: 10.1093/nar/gkaa886   
2020 Wangsanuwat C, Heom KA, Liu E, O'Malley MA, Dey SS. Efficient and cost-effective bacterial mRNA sequencing from low input samples through ribosomal RNA depletion. Bmc Genomics. 21: 717. PMID 33066726 DOI: 10.1186/s12864-020-07134-4