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Richard H. Lathrop - Publications

Affiliations: 
Biomedical Engineering - Ph.D. University of California, Irvine, Irvine, CA 
Area:
Biomedical Engineering, Bioinformatics Biology, Artificial Intelligence
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Durairaj G, Demir Ö, Lim B, Baronio R, Tifrea D, Hall LV, DeForest JC, Lauinger L, Jebril Fallatah MM, Yu C, Bae H, Lin DW, Kim JK, Salehi F, Jang C, ... ... Lathrop RH, et al. Discovery of compounds that reactivate p53 mutants in vitro and in vivo. Cell Chemical Biology. PMID 35948006 DOI: 10.1016/j.chembiol.2022.07.003  0.327
2015 Que RA, Chan SW, Jabaiah AM, Lathrop RH, Da Silva NA, Wang SW. Tuning cellular response by modular design of bioactive domains in collagen. Biomaterials. 53: 309-17. PMID 25890729 DOI: 10.1016/J.Biomaterials.2015.02.074  0.303
2015 Salehi F, Baronio R, Idrogo-Lam R, Vu H, Hall LV, Kaiser P, Lathrop RH. CHOPER filters enable rare mutation detection in complex mutagenesis populations by next-generation sequencing. Plos One. 10: e0116877. PMID 25692681 DOI: 10.1371/Journal.Pone.0116877  0.322
2013 Qi X, Vargas E, Larsen L, Knapp W, Hatfield GW, Lathrop R, Sandmeyer S. Directed DNA shuffling of retrovirus and retrotransposon integrase protein domains. Plos One. 8: e63957. PMID 23691126 DOI: 10.1371/Journal.Pone.0063957  0.385
2013 Wassman CD, Baronio R, Demir Ö, Wallentine BD, Chen CK, Hall LV, Salehi F, Lin DW, Chung BP, Hatfield GW, Richard Chamberlin A, Luecke H, Lathrop RH, Kaiser P, Amaro RE. Computational identification of a transiently open L1/S3 pocket for reactivation of mutant p53. Nature Communications. 4: 1407. PMID 23360998 DOI: 10.1038/Ncomms2361  0.733
2011 Demir Ö, Baronio R, Salehi F, Wassman CD, Hall L, Hatfield GW, Chamberlin R, Kaiser P, Lathrop RH, Amaro RE. Ensemble-based computational approach discriminates functional activity of p53 cancer and rescue mutants. Plos Computational Biology. 7: e1002238. PMID 22028641 DOI: 10.1371/Journal.Pcbi.1002238  0.746
2011 Akers JC, HoDac H, Lathrop RH, Tan M. Identification and functional analysis of CT069 as a novel transcriptional regulator in Chlamydia. Journal of Bacteriology. 193: 6123-31. PMID 21908669 DOI: 10.1128/Jb.05976-11  0.322
2010 Baronio R, Danziger SA, Hall LV, Salmon K, Hatfield GW, Lathrop RH, Kaiser P. All-codon scanning identifies p53 cancer rescue mutations. Nucleic Acids Research. 38: 7079-88. PMID 20581117 DOI: 10.1093/Nar/Gkq571  0.746
2010 Chan SW, Hung SP, Raman SK, Hatfield GW, Lathrop RH, Da Silva NA, Wang SW. Recombinant human collagen and biomimetic variants using a de novo gene optimized for modular assembly. Biomacromolecules. 11: 1460-9. PMID 20481478 DOI: 10.1021/Bm100052Y  0.324
2010 Ringpis GE, Aphasizheva I, Wang X, Huang L, Lathrop RH, Hatfield GW, Aphasizhev R. Mechanism of U insertion RNA editing in trypanosome mitochondria: the bimodal TUTase activity of the core complex. Journal of Molecular Biology. 399: 680-95. PMID 20362585 DOI: 10.1016/J.Jmb.2010.03.050  0.309
2009 Danziger SA, Baronio R, Ho L, Hall L, Salmon K, Hatfield GW, Kaiser P, Lathrop RH. Predicting positive p53 cancer rescue regions using Most Informative Positive (MIP) active learning. Plos Computational Biology. 5: e1000498. PMID 19756158 DOI: 10.1371/Journal.Pcbi.1000498  0.734
2008 Larsen LS, Wassman CD, Hatfield GW, Lathrop RH. Computationally Optimised DNA Assembly of synthetic genes. International Journal of Bioinformatics Research and Applications. 4: 324-36. PMID 18640907 DOI: 10.1504/Ijbra.2008.019578  0.723
2008 Zeng J, Yan J, Wang T, Mosbrook-Davis D, Dolan KT, Christensen R, Stormo GD, Haussler D, Lathrop RH, Brachmann RK, Burgess SM. Genome wide screens in yeast to identify potential binding sites and target genes of DNA-binding proteins. Nucleic Acids Research. 36: e8. PMID 18086703 DOI: 10.1093/Nar/Gkm1117  0.437
2007 Danziger SA, Zeng J, Wang Y, Brachmann RK, Lathrop RH. Choosing where to look next in a mutation sequence space: Active Learning of informative p53 cancer rescue mutants. Bioinformatics (Oxford, England). 23: i104-14. PMID 17646286 DOI: 10.1093/bioinformatics/btm166  0.705
2007 Aeling KA, Steffen NR, Johnson M, Hatfield GW, Lathrop RH, Senear DF. DNA deformation energy as an indirect recognition mechanism in protein-DNA interactions. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 4: 117-25. PMID 17277419 DOI: 10.1109/Tcbb.2007.1000  0.771
2006 Bichutskiy VY, Colman R, Brachmann RK, Lathrop RH. Heterogeneous biomedical database integration using a hybrid strategy: a p53 cancer research database. Cancer Informatics. 2: 277-87. PMID 19458771 DOI: 10.4137/Cin.S0  0.338
2006 Danziger SA, Swamidass SJ, Zeng J, Dearth LR, Lu Q, Chen JH, Cheng J, Hoang VP, Saigo H, Luo R, Baldi P, Brachmann RK, Lathrop RH. Functional census of mutation sequence spaces: the example of p53 cancer rescue mutants. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 3: 114-25. PMID 17048398 DOI: 10.1109/Tcbb.2006.22  0.732
2006 Aeling KA, Opel ML, Steffen NR, Tretyachenko-Ladokhina V, Hatfield GW, Lathrop RH, Senear DF. Indirect recognition in sequence-specific DNA binding by Escherichia coli integration host factor: the role of DNA deformation energy. The Journal of Biological Chemistry. 281: 39236-48. PMID 17035240 DOI: 10.1074/Jbc.M606363200  0.773
2006 Tagwerker C, Zhang H, Wang X, Larsen LS, Lathrop RH, Hatfield GW, Auer B, Huang L, Kaiser P. HB tag modules for PCR-based gene tagging and tandem affinity purification in Saccharomyces cerevisiae. Yeast (Chichester, England). 23: 623-32. PMID 16823883 DOI: 10.1002/Yea.1380  0.392
2004 Wassman CD, Tam PY, Lathrop RH, Weiss GA. Predicting oligonucleotide-directed mutagenesis failures in protein engineering. Nucleic Acids Research. 32: 6407-13. PMID 15585664 DOI: 10.1093/Nar/Gkh977  0.735
2002 Steffen NR, Murphy SD, Lathrop RH, Opel ML, Tolleri L, Hatfield GW. The role of DNA deformation energy at individual base steps for the identification of DNA-protein binding sites. Genome Informatics. International Conference On Genome Informatics. 13: 153-62. PMID 14571384 DOI: 10.11234/Gi1990.13.153  0.773
2002 Steffen NR, Murphy SD, Tolleri L, Hatfield GW, Lathrop RH. DNA sequence and structure: direct and indirect recognition in protein-DNA binding. Bioinformatics (Oxford, England). 18: S22-30. PMID 12169527  0.776
2001 Lathrop RH, Sazhin A, Sun Y, Steffin N, Irani SS. A multi-queue branch-and-bound algorithm for anytime optimal search with biological applications Genome Informatics. International Conference On Genome Informatics. 12: 73-82. PMID 11791226 DOI: 10.11234/Gi1990.12.73  0.334
1999 Lathrop RH. An anytime local-to-global optimization algorithm for protein threading in O(m2n2) space Journal of Computational Biology. 6: 405-418. PMID 10582575 DOI: 10.1089/106652799318355  0.319
1999 Lathrop RH, Steffen NR, Raphael MP, Deeds-Rubin S, Pazzani MJ, Cimoch PJ, See DM, Tilles JG. Knowledge-based avoidance of drug-resistant HIV mutants Ai Magazine. 20: 13-24. DOI: 10.1609/Aimag.V20I1.1437  0.719
1998 Lathrop RH, Rogers RG, Smith TF, White JV. A Bayes-optimal Sequence-structure Theory that Unifies Protein Sequence-structure Recognition and Alignment Bulletin of Mathematical Biology. 60: 1039-1071. DOI: 10.1016/S0092-8240(98)90002-7  0.321
1997 Stultz CM, Nambudripad R, Lathrop RH, White JV. Predicting Protein Structure With Probabilistic Models Advances in Molecular and Cell Biology. 22: 447-506. DOI: 10.1016/S1569-2558(08)60483-X  0.355
1996 Lathrop RH, Smith TF. Global optimum protein threading with gapped alignment and empirical pair score functions Journal of Molecular Biology. 255: 641-665. PMID 8568903 DOI: 10.1006/Jmbi.1996.0053  0.364
1994 Lathrop RH. The protein threading problem with sequence amino acid interaction preferences is np-complete Protein Engineering, Design and Selection. 7: 1059-1068. PMID 7831276 DOI: 10.1093/Protein/7.9.1059  0.345
1994 Jain AN, Dietterich TG, Lathrop RH, Chapman D, Critchlow RE, Bauer BE, Webster TA, Lozano-Perez T. Compass: A shape-based machine learning tool for drug design Journal of Computer-Aided Molecular Design. 8: 635-652. PMID 7738601 DOI: 10.1007/Bf00124012  0.312
1990 Zhu Q, Smith TF, Lathrop RH, Figge J. Acid helix-turn activator motif Proteins: Structure, Function and Genetics. 8: 156-163. PMID 2172962 DOI: 10.1002/Prot.340080205  0.356
1989 Webster TA, Patarca R, Lathrop RH, Smith TF. Potential structural motifs for reverse transcriptases Molecular Biology and Evolution. 6: 317-320. PMID 2482917 DOI: 10.1093/Oxfordjournals.Molbev.A040543  0.38
1988 Webster TA, Lathrop RH, Smith TF. Pattern descriptors and the unidentified reading frame 6 human mtDNA dinucleotide-binding site Proteins: Structure, Function and Genetics. 3: 97-101. PMID 3165195 DOI: 10.1002/Prot.340030204  0.356
1987 Webster TA, Lathrop RH, Smith TF. Prediction of a common structural domain in aminoacyl-tRNA synthetases through use of a new pattern-directed inference system Biochemistry. 26: 6950-6957. PMID 3322392 DOI: 10.1021/Bi00396A014  0.384
1987 Bradley MK, Smith TF, Lathrop RH, Livingston DM, Webster TA. Consensus topography in the ATP binding site of the simian virus 40 and polyomavirus large tumor antigens Proceedings of the National Academy of Sciences of the United States of America. 84: 4026-4030. PMID 3035562 DOI: 10.1073/Pnas.84.12.4026  0.36
1987 Lathrop RH, Webster TA, Smith TF. ARIADNE: pattern-directed inference and hierarchical abstraction in protein structure recognition Communications of the Acm. 30: 909-921. DOI: 10.1145/32206.32207  0.323
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