Jan B. Egan, Ph.D. - Publications

Affiliations: 
2009 Cancer Biology University of Arizona, Tucson, AZ 
Area:
Molecular Biology, Genetics, Epidemiology

5/125 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Hibler EA, Jurutka PW, Egan JB, Hu C, LeRoy EC, Martinez ME, Thompson PA, Jacobs ET. Association between polymorphic variation in VDR and RXRA and circulating levels of vitamin D metabolites. The Journal of Steroid Biochemistry and Molecular Biology. 121: 438-41. PMID 20307661 DOI: 10.1016/J.Jsbmb.2010.03.052  0.509
2010 Haussler MR, Haussler CA, Whitfield GK, Hsieh JC, Thompson PD, Barthel TK, Bartik L, Egan JB, Wu Y, Kubicek JL, Lowmiller CL, Moffet EW, Forster RE, Jurutka PW. The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging. The Journal of Steroid Biochemistry and Molecular Biology. 121: 88-97. PMID 20227497 DOI: 10.1016/J.Jsbmb.2010.03.019  0.318
2010 Egan JB, Thompson PA, Ashbeck EL, Conti DV, Duggan D, Hibler E, Jurutka PW, Leroy EC, Martínez ME, Mount D, Jacobs ET. Genetic polymorphisms in vitamin D receptor VDR/RXRA influence the likelihood of colon adenoma recurrence. Cancer Research. 70: 1496-504. PMID 20145122 DOI: 10.1158/0008-5472.Can-09-3264  0.536
2010 Egan JB, Thompson PA, Vitanov MV, Bartik L, Jacobs ET, Haussler MR, Gerner EW, Jurutka PW. Vitamin D receptor ligands, adenomatous polyposis coli, and the vitamin D receptor FokI polymorphism collectively modulate beta-catenin activity in colon cancer cells. Molecular Carcinogenesis. 49: 337-52. PMID 20043299 DOI: 10.1002/Mc.20603  0.473
2008 Egan JB, Jacobs ET, Martínez ME, Gerner EW, Jurutka PW, Thompson PA. Presence of a TA haplotype in the APC gene containing the common 1822 polymorphism and colorectal adenoma. Cancer Research. 68: 6006-13. PMID 18632657 DOI: 10.1158/0008-5472.Can-08-1084  0.494
Low-probability matches (unlikely to be authored by this person)
1993 Lamont I, Richardson H, Carter DR, Egan JB. Genes for the establishment and maintenance of lysogeny by the temperate coliphage 186 Journal of Bacteriology. 175: 5286-5288. PMID 8349570  0.235
1986 Kalionis B, Dodd IB, Egan JB. Control of gene expression in the P2-related template coliphages. III. DNA sequence of the major control region of phage 186 Journal of Molecular Biology. 191: 199-209. PMID 3806670 DOI: 10.1016/0022-2836(86)90257-3  0.235
1995 Xue Q, Egan JB. Tail sheath and tail tube genes of the temperate coliphage 186 Virology. 212: 218-221. PMID 7676633 DOI: 10.1006/viro.1995.1471  0.233
1982 Hocking SM, Egan JB. Genetic studies of coliphage 186. I. Genes associated with phage morphogenesis Journal of Virology. 44: 1056-1067. PMID 6757460  0.233
2005 Dodd IB, Shearwin KE, Egan JB. Revisited gene regulation in bacteriophage λ Current Opinion in Genetics and Development. 15: 145-152. PMID 15797197 DOI: 10.1016/J.Gde.2005.02.001  0.224
1998 Portelli R, Dodd IB, Xue Q, Egan JB. The late-expressed region of the temperature coliphage 186 genome Virology. 248: 117-130. PMID 9705261 DOI: 10.1006/viro.1998.9263  0.224
2020 Chandrashekar P, Ahmadinejad N, Wang J, Sekulic A, Egan JB, Asmann YW, Kumar S, Maley C, Liu L. Somatic selection distinguishes oncogenes and tumor suppressor genes. Bioinformatics (Oxford, England). 36: 1712-1717. PMID 32176769 DOI: 10.1093/Bioinformatics/Btz851  0.223
1986 Kalionis B, Pritchard M, Egan JB. Control of gene expression in the P2-related temperate coliphages. IV. Concerning the late control gene and control of its transcription Journal of Molecular Biology. 191: 211-220. PMID 3806671 DOI: 10.1016/0022-2836(86)90258-5  0.223
1982 Hocking SM, Egan JB. Genetic map of coliphage 186 from a novel use of marker rescue frequencies Mgg Molecular & General Genetics. 187: 87-95. PMID 6962313 DOI: 10.1007/BF00384388  0.22
1990 Sivaprasad AV, Jarvinen R, Puspurs A, Egan JB. DNA replication studies with coliphage 186. III. A single phage gene is required for phage 186 replication Journal of Molecular Biology. 213: 449-463. PMID 2352277 DOI: 10.1016/S0022-2836(05)80207-4  0.216
2015 Kortüm KM, Langer C, Monge J, Bruins L, Zhu YX, Shi CX, Jedlowski P, Egan JB, Ojha J, Bullinger L, Kull M, Ahmann G, Rasche L, Knop S, Fonseca R, et al. Longitudinal analysis of 25 sequential sample-pairs using a custom multiple myeloma mutation sequencing panel (M(3)P). Annals of Hematology. 94: 1205-11. PMID 25743686 DOI: 10.1007/s00277-015-2344-9  0.216
1968 Morse ML, Hill KL, Egan JB, Hengstenberg W. Metabolism of lactose by Staphylococcus aureus and its genetic basis. Journal of Bacteriology. 95: 2270-4. PMID 5669899  0.213
1975 Kretschmer PJ, Egan JB. Genetic map of the staphylococcal bacteriophage phi11 Journal of Virology. 16: 642-651. PMID 125802  0.208
2020 Zong N, Sharma DK, Yu Y, Egan JB, Davila JI, Wang C, Jiang G. Developing a FHIR-based Framework for Phenome Wide Association Studies: A Case Study with A Pan-Cancer Cohort. Amia Joint Summits On Translational Science Proceedings. Amia Joint Summits On Translational Science. 2020: 750-759. PMID 32477698  0.2
2023 Budhraja KK, McDonald BR, Stephens MD, Contente-Cuomo T, Markus H, Farooq M, Favaro PF, Connor S, Byron SA, Egan JB, Ernst B, McDaniel TK, Sekulic A, Tran NL, Prados MD, et al. Genome-wide analysis of aberrant position and sequence of plasma DNA fragment ends in patients with cancer. Science Translational Medicine. 15: eabm6863. PMID 36630480 DOI: 10.1126/scitranslmed.abm6863  0.195
1989 Richardson H, Puspurs A, Egan JB. Control of gene expression in the P2-related temperate coliphage 186. VI. Sequence analysis of the early lytic region Journal of Molecular Biology. 206: 251-255. PMID 2704042 DOI: 10.1016/0022-2836(89)90539-1  0.195
1998 Shearwin KE, Brumby AM, Egan JB. The tum protein of coliphage 186 is an antirepressor Journal of Biological Chemistry. 273: 5708-5715. PMID 9488703 DOI: 10.1074/jbc.273.10.5708  0.194
1984 Raftery LA, Egan JB, Cline SW, Yarus M. Defined set of cloned termination suppressors: in vivo activity of isogenetic UAG, UAA, and UGA suppressor tRNAs. Journal of Bacteriology. 158: 849-59. PMID 6327642 DOI: 10.1128/Jb.158.3.849-859.1984  0.187
2014 Bryce AH, Borad MJ, Condjella RM, Egan JB, Champion MD, Hunt KS, McWilliams RR, McCullough AE, Kurdoglu A, Aldrich J, Izatt T, Nasser S, Christoforides A, Phillips L, Liang WS, et al. A study of real-time CLIA-enabled whole genome tumor sequencing: Results for testicular cancer and sarcomatoid RCC. Journal of Clinical Oncology. 32: 463-463. DOI: 10.1200/Jco.2014.32.4_Suppl.463  0.187
2014 Egan JB, Bryce AH, Champion MD, Liang WS, Fonseca R, McCullough AE, Barrett MT, Hunt K, Condjella RM, McWilliams RR, Mastrian SD, LoBello J, Hoff DV, Craig DW, Stewart AK, et al. Abstract 4694: Indices of actionability and clinical utility in a CLIA-enabled study of whole genome/exome/RNA sequencing in 33 cancer patients: Actionable vs. utility Cancer Research. 74: 4694-4694. DOI: 10.1158/1538-7445.Am2014-4694  0.186
1992 Dibbens JA, Gregory SL, Egan JB. Control of gene expression in the temperate coliphage 186. X. The cl repressor directly represses transcription of the late control gene B Molecular Microbiology. 6: 2643-2650. PMID 1447973  0.181
2012 Braggio E, O'Neill BP, Egan J, Valdez R, McPhail E, Lopes M, Schiff D, Tibes R, Stewart K, Fonseca R. Genome-Wide Analysis Uncovers Recurrent Alterations in Primary Central Nervous System Lymphomas Blood. 120: 420-420. DOI: 10.1182/BLOOD.V120.21.420.420  0.176
2002 Dodd IB, Egan JB. Action at a distance in CI repressor regulation of the bacteriophage 186 genetic switch Molecular Microbiology. 45: 697-710. PMID 12139616 DOI: 10.1046/j.1365-2958.2002.03038.x  0.175
1990 Dodd IB, Kalionis B, Egan JB. Control of gene expression in the temperate coliphage 186. VIII. Control of lysis and lysogeny by a transcriptional switch involving face-to-face promoters Journal of Molecular Biology. 214: 27-37. PMID 2370665 DOI: 10.1016/0022-2836(90)90144-B  0.174
2014 Egan JB, Barrett MT, Champion MD, Middha S, Lenkiewicz E, Evers L, Francis P, Schmidt J, Shi CX, Van Wier S, Badar S, Ahmann G, Kortuem KM, Boczek NJ, Fonseca R, et al. Whole genome analyses of a well-differentiated liposarcoma reveals novel SYT1 and DDR2 rearrangements. Plos One. 9: e87113. PMID 24505276 DOI: 10.1371/Journal.Pone.0087113  0.174
2004 Dodd IB, Shearwin KE, Perkins AJ, Burr T, Hochschild A, Egan JB. Cooperativity in long-range gene regulation by the λ CI repressor Genes and Development. 18: 344-354. PMID 14871931 DOI: 10.1101/Gad.1167904  0.174
2009 Egan J, Keats JJ, Bergsagel PL, Tiedemann RE, Carpten J, Stewart AK. Comparative Genomic Hybridization, Gene Expression Profiling and Whole Genome Sequencing Analysis of Disease Progression in Myeloma Reveals Vigorous Clonal Evolution in Patients with High Baseline Genetic Risk. Blood. 114: 2810-2810. DOI: 10.1182/BLOOD.V114.22.2810.2810  0.173
2014 Borad MJ, Champion MD, Egan JB, Liang WS, Fonseca R, Bryce AH, McCullough AE, Barrett MT, Hunt K, Patel MD, Young SW, Collins JM, Silva AC, Condjella RM, Block M, et al. Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma. Plos Genetics. 10: e1004135. PMID 24550739 DOI: 10.1371/Journal.Pgen.1004135  0.172
2007 Schubert RA, Dodd IB, Egan JB, Shearwin KE. Cro's role in the CI Cro bistable switch is critical for {lambda}'s transition from lysogeny to lytic development. Genes & Development. 21: 2461-72. PMID 17908932 DOI: 10.1101/Gad.1584907  0.172
1996 Brumby AM, Lamont I, Dodd IB, Egan JB. Defining the SOS operon of coliphage 186 Virology. 219: 105-114. PMID 8623519 DOI: 10.1006/viro.1996.0227  0.171
1989 Richardson H, Egan JB. DNA replication studies with coliphage 186. II. Depression of host replication by a 186 gene Journal of Molecular Biology. 206: 59-68. PMID 2704043 DOI: 10.1016/0022-2836(89)90523-8  0.161
2013 Braggio E, O'Neill BP, Van Wier S, Ojha J, ayres-Silva J, Valdez R, Egan J, McPhail E, Lopes MB, Schiff D, Tibes R, Stewart K, Fonseca R. The Genomic Landscape Of Primary Central Nervous System Lymphomas Blood. 122: 504-504. DOI: 10.1182/BLOOD.V122.21.504.504  0.161
1985 Pritchard M, Egan JB. Control of gene expression in P2-related coliphages: the in vitro transcription pattern of coliphage 186. The Embo Journal. 4: 3599-3604. PMID 3912173  0.16
2012 Egan J, Kortuem KM, Shi C, Schmidt J, Craig D, Carpten J, Stewart K. The Myeloma Genome in Drug Refractory Extra-Medullary Disease Identifies Mutations in Proteasome, Cereblon and Glucocorticoid Pathways Blood. 120: 3968-3968. DOI: 10.1182/blood.v120.21.3968.3968  0.159
1992 Dibbens JA, Egan JB. Control of gene expression in the temperate coliphage 186. IX. B is the sole phage function needed to activate transcription of the phage late genes Molecular Microbiology. 6: 2629-2642. PMID 1447972  0.157
1981 Finnegan J, Egan JB. In vivo transcription studies of coliphage 186 Journal of Virology. 38: 987-995. PMID 6165842  0.156
2018 Farooq M, Egan JB, McDonald B, Markus H, Contente-Cuomo T, Fernandez-Zapico M, Vasmatzis G, Braggio E, Borad MJ, Murtaza M. Detection of copy number aberrations in cholangiocarcinoma using shallow whole genome sequencing of plasma DNA. Journal of Clinical Oncology. 36: 293-293. DOI: 10.1200/Jco.2018.36.4_Suppl.293  0.155
1982 Hocking SM, Egan JB. Genetic studies of coliphage 186. II. Genes associated with phage replication and host cell lysis Journal of Virology. 44: 1068-1071. PMID 6757461  0.155
1988 Lamont I, Kalionis B, Egan JB. Control of gene expression in the P2-related temperate coliphages. V. The use of sequence analysis of 186 vir mutants to indicate presumptive repressor binding sites Journal of Molecular Biology. 199: 379-382. PMID 3351929 DOI: 10.1016/0022-2836(88)90321-X  0.154
2001 Neufing PJ, Shearwin KE, Egan JB. Establishing lysogenic transcription in the temperate coliphage 186 Journal of Bacteriology. 183: 2376-2379. PMID 11244081 DOI: 10.1128/JB.183.7.2376-2379.2001  0.15
2015 Braggio E, Van Wier S, Ojha J, McPhail E, Asmann YW, Egan J, da Silva JA, Schiff D, Lopes MB, Decker PA, Valdez R, Tibes R, Eckloff B, Witzig TE, Stewart AK, et al. Genome-Wide Analysis Uncovers Novel Recurrent Alterations in Primary Central Nervous System Lymphomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 3986-94. PMID 25991819 DOI: 10.1158/1078-0432.Ccr-14-2116  0.149
1972 Woods WH, Egan JB. Integration stie of noninducible coliphage 186. Journal of Bacteriology. 111: 303-7. PMID 4559723  0.148
2013 Schmidt J, Braggio E, Kortuem KM, Egan JB, Zhu YX, Xin CS, Tiedemann RE, Palmer SE, Garbitt VM, McCauley D, Kauffman M, Shacham S, Chesi M, Bergsagel PL, Stewart AK. Genome-wide studies in multiple myeloma identify XPO1/CRM1 as a critical target validated using the selective nuclear export inhibitor KPT-276. Leukemia. 27: 2357-65. PMID 23752175 DOI: 10.1038/leu.2013.172  0.148
1996 Neufing PJ, Shearwin KE, Camerotto J, Egan JB. The CII protein of bacteriophage 186 establishes lysogeny by activating a promoter upstream of the lysogenic promoter Molecular Microbiology. 21: 751-761. PMID 8878038 DOI: 10.1046/J.1365-2958.1996.351394.X  0.146
1966 Hogness DS, Doerfler W, Egan JB, Black LW. The position and orientation of genes in lambda and lambda dg DNA. Cold Spring Harbor Symposia On Quantitative Biology. 31: 129-38. PMID 4866370 DOI: 10.1101/Sqb.1966.031.01.020  0.145
2013 Borad MJ, Egan J, Champion M, Hunt K, McWilliams R, McCullough A, Aldrich J, Nasser S, Liang W, Barrett M, Craig D, Ramanathan R, Carpten J, Stewart AK, Bryce A. Abstract CT112: Implementation of CLIA enabled integrated whole genome (WGS)/exome (WES)/transcriptome (RNAseq) next-gen sequencing to identify therapeutically relevant targets in advanced cancer patients Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C66  0.143
2009 Palmer AC, Ahlgren-Berg A, Egan JB, Dodd IB, Shearwin KE. Potent transcriptional interference by pausing of RNA polymerases over a downstream promoter. Molecular Cell. 34: 545-55. PMID 19524535 DOI: 10.1016/J.Molcel.2009.04.018  0.141
2012 Liang WS, Craig DW, Carpten J, Borad MJ, Demeure MJ, Weiss GJ, Izatt T, Sinari S, Christoforides A, Aldrich J, Kurdoglu A, Barrett M, Phillips L, Benson H, Tembe W, ... ... Egan JB, et al. Genome-wide characterization of pancreatic adenocarcinoma patients using next generation sequencing. Plos One. 7: e43192. PMID 23071490 DOI: 10.1371/Journal.Pone.0043192  0.141
2015 Kortüm KM, Langer C, Monge J, Bruins L, Egan JB, Zhu YX, Shi CX, Jedlowski P, Schmidt J, Ojha J, Bullinger L, Liebisch P, Kull M, Champion MD, Van Wier S, et al. Targeted sequencing using a 47 gene multiple myeloma mutation panel (M(3) P) in -17p high risk disease. British Journal of Haematology. 168: 507-10. PMID 25302557 DOI: 10.1111/bjh.13171  0.139
2016 Borad MJ, Egan JB, Condjella RM, Liang WS, Fonseca R, Ritacca NR, McCullough AE, Barrett MT, Hunt KS, Champion MD, Patel MD, Young SW, Silva AC, Ho TH, Halfdanarson TR, et al. Clinical Implementation of Integrated Genomic Profiling in Patients with Advanced Cancers. Scientific Reports. 6: 25. PMID 28003660 DOI: 10.1038/S41598-016-0021-4  0.139
1994 Williams SG, Egan JB. DNA replication studies with coliphage 186: The involvement of the Escherichia coli DnaA protein in 186 replication is indirect Journal of Bacteriology. 176: 6039-6044. PMID 7928964  0.139
2014 Patrick O'Neill B, Braggio E, O'Neill BP, Van Wier S, Ojha J, McPhail E, Asmann Y, Egan J, Ayres da Silva J, Schiff D, Lopes MB, Valdez R, Tibes R, Eckloff B, Stewart AK, et al. GENOME-WIDE ANALYSIS UNCOVERS RECURRENT ALTERATIONS IN PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMAS (PCNSL) Neuro-Oncology. 16: iii43-iii43. DOI: 10.1093/Neuonc/Nou209.7  0.137
1993 Dodd IB, Reed MR, Egan JB. The Cro-like Apl repressor of coliphage 186 is required for prophage excision and binds near the phage attachment site Molecular Microbiology. 10: 1139-1150. PMID 7934863  0.137
2021 Velez MG, Kosiorek HE, Egan JB, McNatty AL, Riaz IB, Hwang SR, Stewart GA, Ho TH, Moore CN, Singh P, Sharpsten RK, Costello BA, Bryce AH. Differential impact of tumor suppressor gene (TP53, PTEN, RB1) alterations and treatment outcomes in metastatic, hormone-sensitive prostate cancer. Prostate Cancer and Prostatic Diseases. PMID 34294873 DOI: 10.1038/s41391-021-00430-4  0.136
2013 Braggio E, Egan JB, Fonseca R, Stewart AK. Lessons from next-generation sequencing analysis in hematological malignancies. Blood Cancer Journal. 3: e127. PMID 23872706 DOI: 10.1038/bcj.2013.26  0.136
2012 Schmidt J, Braggio E, Chesi M, Egan J, Zhu YX, Shi C, Palmer S, Garbitt V, McCauley D, Shacham S, Kauffman M, Bergsagel L, Stewart K. Genome Wide Studies in Multiple Myeloma Identify XPO1/CRM-1 As a Critical Target Validated Using the Selective Inhibitor of Nuclear Export (SINE) KPT-276 Blood. 120: 573-573. DOI: 10.1182/BLOOD.V120.21.573.573  0.135
1995 Xue Q, Egan JB. DNA sequence of tail fiber genes of coliphage 186 and evidence for a common ancestor shared by dsDNA phage fiber genes Virology. 212: 128-133. PMID 7676622 DOI: 10.1006/viro.1995.1461  0.135
2019 Velez MGG, Kosiorek H, Egan J, Bryce A. Prognostic value of tumour suppression genes (TP53, PTEN, Rb) in metastatic hormone sensitive prostate cancer Annals of Oncology. 30: v344-v345. DOI: 10.1093/annonc/mdz248.035  0.134
2017 Bennani NN, Ansell SM, Witzig TE, Feldman AL, McAllister TM, Lazaridis KN, Egan JB, Stewart AK, Nowakowski GS. Clinical utility of molecular testing to select therapy in relapsed/refractory non-Hodgkin lymphoma: Mayo Clinic Center for Individualized Medicine experience. Journal of Clinical Oncology. 35: 11571-11571. DOI: 10.1200/JCO.2017.35.15_SUPPL.11571  0.132
2012 Egan JB, Shi CX, Tembe W, Christoforides A, Kurdoglu A, Sinari S, Middha S, Asmann Y, Schmidt J, Braggio E, Keats JJ, Fonseca R, Bergsagel PL, Craig DW, Carpten JD, et al. Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides. Blood. 120: 1060-6. PMID 22529291 DOI: 10.1182/Blood-2012-01-405977  0.13
2017 Yokoda R, Nagalo BM, Arora M, Egan JB, Bogenberger JM, DeLeon TT, Zhou Y, Ahn DH, Borad MJ. Oncolytic virotherapy in upper gastrointestinal tract cancers. Oncolytic Virotherapy. 7: 13-24. PMID 29616200 DOI: 10.2147/OV.S161397  0.129
2015 Hart SN, Moore RM, Zimmermann MT, Oliver GR, Egan JB, Bryce AH, Kocher JP. PANDA: pathway and annotation explorer for visualizing and interpreting gene-centric data. Peerj. 3: e970. PMID 26038725 DOI: 10.7717/Peerj.970  0.129
2019 Bryce AH, Egan JB, Smadbeck JB, Johnson SH, Murphy SJ, Harris FR, Halling GC, Terra SBSP, Cheville J, Pagliaro L, Leibovich B, Costello BA, Vasmatzis G. Shared and unique genomic structural variants of different histological components within testicular germ cell tumours identified with mate pair sequencing. Scientific Reports. 9: 3586. PMID 30837548 DOI: 10.1038/S41598-019-39956-Y  0.127
1972 Pilarski LM, Egan JB. Topology of DNA and N gene expression in coliphage lambda. Nature: New Biology. 237: 102-4 passim. PMID 4503845 DOI: 10.1038/NEWBIO237102A0  0.126
2005 Shearwin KE, Callen BP, Egan JB. Transcriptional interference - A crash course Trends in Genetics. 21: 339-345. PMID 15922833 DOI: 10.1016/J.Tig.2005.04.009  0.125
1989 Lamont I, Brumby AM, Egan JB. UV induction of coliphage 186: Prophage induction as an SOS function Proceedings of the National Academy of Sciences of the United States of America. 86: 5492-5496. PMID 2664785  0.124
1997 Reed MR, Shearwin KE, Pell LM, Egan JB. The dual role of Apl in prophage induction of coliphage 186 Molecular Microbiology. 23: 669-681. PMID 9157239 DOI: 10.1046/J.1365-2958.1997.2521620.X  0.124
2021 Oliver GR, Marcano-Bonilla S, Quist J, Tolosa EJ, Iguchi E, Swanson AA, Hoppman NL, Schwab T, Sigafoos A, Prodduturi N, Voss JS, Knight SM, Zhang J, Fadra N, Urrutia R, ... ... Egan JB, et al. LPCAT1-TERT fusions are uniquely recurrent in epithelioid trophoblastic tumors and positively regulate cell growth. Plos One. 16: e0250518. PMID 34033669 DOI: 10.1371/journal.pone.0250518  0.122
1975 Younghusband HB, Egan JB, Inman RB. Characterization of the DNA from bacteriophage P2-186 hybrids and physical mapping of the 186 chromosome Mgg Molecular & General Genetics. 140: 101-110. PMID 1105151 DOI: 10.1007/BF00329778  0.122
2015 Hart SN, Moore RM, Zimmermann MT, Oliver GR, Egan JB, Bryce AH, Kocher JPA. PANDA: Pathway and annotation explorer for visualizing and interpreting gene-centric data Peerj. 2015. DOI: 10.7717/peerj.970  0.122
2005 Sneppen K, Dodd IB, Shearwin KE, Palmer AC, Schubert RA, Callen BP, Egan JB. A mathematical model for transcriptional interference by RNA polymerase traffic in Escherichia coli Journal of Molecular Biology. 346: 399-409. PMID 15670592 DOI: 10.1016/J.Jmb.2004.11.075  0.121
2001 Dodd IB, Perkins AJ, Tsemitsidis D, Egan JB. Octamerization of λ CI repressor is needed for effective repression of PRM and efficient switching from lysogeny Genes and Development. 15: 3013-3022. PMID 11711436 DOI: 10.1101/gad.937301  0.119
1997 Pountney DL, Tiwari RP, Egan JB. Metal- and DNA-binding properties and mutational analysis of the transcription activating factor, B, of coliphage 186: A prokaryotic C4 zinc- finger protein Protein Science. 6: 892-902. PMID 9098899  0.118
2017 Egan JB, Marks DL, Hogenson TL, Vrabel AM, Sigafoos AN, Tolosa EJ, Carr RM, Safgren SL, Hesles EE, Almada LL, Romecin-Duran PA, Iguchi E, Ala'Aldeen A, Kocher JA, Oliver GR, et al. Molecular Modeling and Functional Analysis of Exome Sequencing-Derived Variants of Unknown Significance Identify a Novel, Constitutively Active FGFR2 Mutant in Cholangiocarcinoma. Jco Precision Oncology. 2017. PMID 30761385 DOI: 10.1200/PO.17.00018  0.117
2004 Callen BP, Shearwin KE, Egan JB. Transcriptional interference between convergent promoters caused by elongation over the promoter Molecular Cell. 14: 647-656. PMID 15175159 DOI: 10.1016/J.Molcel.2004.05.010  0.114
2017 Bryce AH, Egan JB, Borad MJ, Stewart AK, Nowakowski GS, Chanan-Khan A, Patnaik MM, Ansell SM, Banck MS, Robinson SI, Mansfield AS, Klee EW, Oliver GR, McCormick JB, Huneke NE, et al. Experience with precision genomics and tumor board, indicates frequent target identification, but barriers to delivery. Oncotarget. 27145-27154. PMID 28423702 DOI: 10.18632/Oncotarget.16057  0.114
2006 Pinkett HW, Shearwin KE, Stayrook S, Dodd IB, Burr T, Hochschild A, Egan JB, Lewis M. The structural basis of cooperative regulation at an alternate genetic switch Molecular Cell. 21: 605-615. PMID 16507359 DOI: 10.1016/J.Molcel.2006.01.019  0.112
1979 Finnegan J, Egan JB. Physical map of the coliphage 186 chromosome - I. Gene content of the BamHI, PstI and other restriction fragments Mgg Molecular & General Genetics. 172: 287-293. PMID 45612 DOI: 10.1007/BF00271728  0.109
2000 Shearwin KE, Egan JB. Establishment of lysogeny in bacteriophage 186. DNA binding and transcriptional activation by the CII protein Journal of Biological Chemistry. 275: 29113-29122. PMID 10871623 DOI: 10.1074/Jbc.M004574200  0.107
1996 Dodd IB, Egan JB. The Escherichia coli retrons Ec67 and Ec86 replace DNA between the cos site and a transcription terminator of a 186-related prophage Virology. 219: 115-124. PMID 8623520 DOI: 10.1006/viro.1996.0228  0.106
2012 Keats JJ, Chesi M, Egan JB, Garbitt VM, Palmer SE, Braggio E, Van Wier S, Blackburn PR, Baker AS, Dispenzieri A, Kumar S, Rajkumar SV, Carpten JD, Barrett M, Fonseca R, et al. Clonal competition with alternating dominance in multiple myeloma. Blood. 120: 1067-76. PMID 22498740 DOI: 10.1182/Blood-2012-01-405985  0.106
2018 Lamberti D, Cristinziano G, Porru M, Leonetti C, Egan JB, Shi CX, Buglioni S, Amoreo CA, Castellani L, Borad MJ, Alemà S, Anastasi S, Segatto O. HSP90 inhibition drives degradation of FGFR2 fusion proteins: implications for treatment of cholangiocarcinoma. Hepatology (Baltimore, Md.). PMID 30067876 DOI: 10.1002/hep.30127  0.101
2021 Ledet EM, Burgess EF, Sokolova AO, Jaeger EB, Hatton W, Moses M, Miller P, Cotogno P, Layton J, Barata P, Lewis BE, Nakazawa M, Zhu J, Dellinger B, Elrefai S, ... ... Egan JB, et al. Comparison of germline mutations in African American and Caucasian men with metastatic prostate cancer. The Prostate. PMID 33792945 DOI: 10.1002/pros.24123  0.1
1991 Gille H, Egan JB, Roth A, Messer W. The FIS protein binds and bends the origin of chromosomal DNA replication, oriC, of Escherichia coli Nucleic Acids Research. 19: 4167-4172. PMID 1870971 DOI: 10.1093/Nar/19.15.4167  0.098
2020 Arora M, Bogenberger JM, Abdelrahman A, Leiting JL, Chen X, Egan JB, Kasimsetty A, Lenkiewicz E, Malasi S, Uson PLS, Nagalo BM, Zhou Y, Salomao MA, Kosiorek HE, Braggio E, et al. Evaluation of NUC-1031: a first-in-class ProTide in biliary tract cancer. Cancer Chemotherapy and Pharmacology. PMID 32440762 DOI: 10.1007/s00280-020-04079-z  0.098
2021 Arora M, Bogenberger JM, Abdelrahman AM, Yonkus J, Alva-Ruiz R, Leiting JL, Chen X, Serrano Uson Junior PL, Dumbauld CR, Baker AT, Gamb SI, Egan JB, Zhou Y, Nagalo BM, Meurice N, et al. Synergistic Combination of Cytotoxic Chemotherapy and Cyclin Dependent Kinase 4/6 Inhibitors in Biliary Tract Cancers. Hepatology (Baltimore, Md.). PMID 34407567 DOI: 10.1002/hep.32102  0.096
1986 Argos P, Landy A, Abremski K, Egan JB, Haggard-Ljungquist E, Hoess RH, Kahn ML, Kalionis B, Narayana SV, Pierson LS. The integrase family of site-specific recombinases: regional similarities and global diversity. The Embo Journal. 5: 433-440. PMID 3011407 DOI: 10.1002/J.1460-2075.1986.Tb04229.X  0.096
2021 Farooq M, Markus H, McDonald B, Egan JB, Contente-Cuomo T, Odenheimer A, Fernandez-Zapico M, Borad MJ, Murtaza M. Detection of FGFR fusions in intrahepatic cholangiocarcinoma using targeted RNA sequencing. Journal of Clinical Oncology. 39: e16185-e16185. DOI: 10.1200/JCO.2021.39.15_SUPPL.E16185  0.092
1987 Dodd IB, Egan JB. Systematic method for the detection of potential λ Cro-like DNA-binding regions in proteins Journal of Molecular Biology. 194: 557-564. PMID 3625774 DOI: 10.1016/0022-2836(87)90681-4  0.088
2013 Egan JB, Kortuem KM, Kurdoglu A, Izatt T, Aldrich J, Reiman R, Phillips L, Baker A, Shi CX, Schmidt J, Liang WS, Craig DW, Carpten JD, Stewart AK. Extramedullary myeloma whole genome sequencing reveals novel mutations in Cereblon, proteasome subunit G2 and the glucocorticoid receptor in multi drug resistant disease. British Journal of Haematology. 161: 748-51. PMID 23480694 DOI: 10.1111/bjh.12291  0.088
1972 Egan JB, Hogness DS. The topography of lambda DNA: isolation of ordered fragments and the physical mapping of point mutations. Journal of Molecular Biology. 71: 363-81. PMID 4635989 DOI: 10.1016/0022-2836(72)90357-9  0.088
1979 Saint RB, Egan JB. Restriction cleavage maps of coliphages 186 and P2. Molecular & General Genetics : Mgg. 171: 79-89. PMID 286152 DOI: 10.1007/BF00274018  0.083
1982 Hocking SM, Egan JB. Genetic characterization of twelve P2-186 hybrid bacteriophages Mgg Molecular & General Genetics. 187: 174-176. PMID 6962312 DOI: 10.1007/BF00384403  0.083
1998 Coates NJ, Dibbens JA, Moffat KG, Egan JB. The use of oriC-dependent phage infection to characterize the ultra violet (UV)-induced inhibition of initiation of DNA replication in Escherichia coli Mutation Research - Dna Repair. 408: 147-157. PMID 9739817 DOI: 10.1016/S0921-8777(98)00027-5  0.082
1974 Woods WH, Egan JB. Prophage induction of noninducible coliphage 186 Journal of Virology. 14: 1349-1356. PMID 4610182  0.08
1982 Wangel AG, Milton A, Egan JB. Spontaneous plaque forming cells in the peripheral blood of patients with systemic lupus erythematosus. Clinical and Experimental Immunology. 49: 41-9. PMID 6751633  0.078
1989 Verma M, Moffat KG, Egan JB. UV irradiation inhibits initiation of DNA replication from oriC in Escherichia coli Mgg Molecular & General Genetics. 216: 446-454. PMID 2526290 DOI: 10.1007/BF00334389  0.078
1990 Dodd IB, Egan JB. Improved detection of helix-turn-helix DNA-binding motifs in protein sequences Nucleic Acids Research. 18: 5019-5026. PMID 2402433 DOI: 10.1093/nar/18.17.5019  0.077
2017 Yokoda R, Nagalo BM, Vernon B, Oklu R, Albadawi H, DeLeon TT, Zhou Y, Egan JB, Duda DG, Borad MJ. Oncolytic virus delivery: from nano-pharmacodynamics to enhanced oncolytic effect. Oncolytic Virotherapy. 6: 39-49. PMID 29184854 DOI: 10.2147/OV.S145262  0.076
1975 Bradley C, Ling OP, Egan JB. Isolation of phage P2-186 intervarietal hybrids and 186 insertion mutants Mgg Molecular & General Genetics. 140: 123-135. PMID 1105153 DOI: 10.1007/BF00329780  0.076
2016 Bryce AH, Borad MJ, Egan JB, Condjella RM, Liang WS, Fonseca R, McCullough AE, Hunt KS, Ritacca NR, Barrett MT, Patel MD, Young SW, Silva AC, Ho TH, Halfdanarson TR, et al. Comprehensive Genomic Analysis of Metastatic Mucinous Urethral Adenocarcinoma Guides Precision Oncology Treatment: Targetable EGFR Amplification Leading to Successful Treatment With Erlotinib. Clinical Genitourinary Cancer. PMID 28057415 DOI: 10.1016/J.Clgc.2016.11.001  0.074
2014 Liang WS, Aldrich J, Nasser S, Kurdoglu A, Phillips L, Reiman R, McDonald J, Izatt T, Christoforides A, Baker A, Craig C, Egan JB, Chase DM, Farley JH, Bryce AH, et al. Simultaneous characterization of somatic events and HPV-18 integration in a metastatic cervical carcinoma patient using DNA and RNA sequencing. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 24: 329-38. PMID 24418928 DOI: 10.1097/Igc.0000000000000049  0.072
1973 Pilarksi LM, Egan JB. Role of DNA topology in transcription of coliphage lambda in vivo. II. DNA topology protects the template from exonuclease attack. Journal of Molecular Biology. 76: 257-66. PMID 4579547 DOI: 10.1016/0022-2836(73)90389-6  0.067
1973 Kretschmer PJ, Egan JB. Isolation of a suppressor host bacterium in Staphylococcus aureus Journal of Bacteriology. 116: 84-87. PMID 4270444  0.057
1961 EGAN JB, HOLLOWAY BW. Genetic studies on lysogeny in Pseudomonas aeruginosa. The Australian Journal of Experimental Biology and Medical Science. 39: 9-17. PMID 13725887  0.056
2017 Myers CE, Hoelzinger DB, Truong TN, Chew LA, Myles A, Chaudhuri L, Egan JB, Liu J, Gendler SJ, Cohen PA. Chemotherapy can induce weight normalization of morbidly obese mice despite undiminished ingestion of high fat diet. Oncotarget. PMID 28076839 DOI: 10.18632/Oncotarget.14576  0.054
1965 EGAN JB, MORSE ML. CARBOHYDRATE TRANSPORT IN STAPHYLOCOCCUS AUREUS I. GENETIC AND BIOCHEMICAL ANALYSIS OF A PLEIOTROPIC TRANSPORT MUTANT. Biochimica Et Biophysica Acta. 97: 310-9. PMID 14292840  0.054
1985 Verma M, Egan JB. Phenotypic variations in strain AB1157 cultivars of Escherichia coli from different sources Journal of Bacteriology. 164: 1381-1382. PMID 3905771  0.053
1981 Hooper I, Egan JB. Coliphage 186 infection requires host initiation functions dnaA and dnaC Journal of Virology. 40: 599-601. PMID 7033562  0.044
1967 Hengstenberg W, Egan JB, Morse ML. Carbohydrate transport in Staphylococcus aureus. V. The accumulation of phosphorylated carbohydrate derivatives, and evidence for a new enzyme-splitting lactose phosphate. Proceedings of the National Academy of Sciences of the United States of America. 58: 274-9. PMID 4292101  0.031
2005 Trusina A, Sneppen K, Dodd IB, Shearwin KE, Egan JB. Functional alignment of regulatory networks: a study of temperate phages. Plos Computational Biology. 1: e74. PMID 16477325 DOI: 10.1371/Journal.Pcbi.0010074  0.028
2019 Arora M, Bogenberger JM, Nagalo MB, Zhou Y, Kannan L, Egan J, Yokoda RT, Ahn DH, Bekaii-Saab T, Borad M. 413 – Synergy of Cyclin Dependent Kinase 4/6 (CDK4/6) Inhibitors with Cytotoxic Chemotherapy in Cholangiocarcinoma Gastroenterology. 156: S-1198. DOI: 10.1016/S0016-5085(19)39973-1  0.027
1968 Hengstenberg W, Egan JB, Morse ML. Carbohydrate transport in Staphylococcus aureus. VI. The nature of the derivatives accumulated. The Journal of Biological Chemistry. 243: 1881-5. PMID 4869132  0.026
1966 Egan JB, Morse ML. Carbohydrate transport in Staphylococcus aureus. 3. Studies of the transport process. Biochimica Et Biophysica Acta. 112: 63-73. PMID 5947899  0.023
1979 Buckley TF, Egan JB. Studies on chocolate agar. Part II. The importance of the method of preparation of chocolate agar plates and the effects of this on the isolation rate of Pneumococci and Haemophilus from sputum Journal of the Academy of Medical Laboratory Science. 1: 27-30.  0.022
1979 Buckley TF, Egan JB. Studies on chocolate agar. Part I. The importance of the basal media used in chocolate agar plates and the effects of this on the efficiency of sputum culture for Haemophilus and Pneumococci Journal of the Academy of Medical Laboratory Science. 1: 21-25.  0.021
1973 Button DK, Egan JB, Hengstenberg W, Morse ML. Carbohydrate transport in staphylococcus aureus IV. Maltose accumulation and metabolism Biochemical and Biophysical Research Communications. 52: 850-855. PMID 4710567 DOI: 10.1016/0006-291X(73)91015-2  0.017
1969 Lawson JS, Brand IA, Lane A, Keane WM, Yeatman JS, Egan JB. Graduate training. The availability of hospital experience for recent medical graduates in Victoria. The Medical Journal of Australia. 2: 1018-21. PMID 5373219  0.01
1960 HOLLOWAY BW, EGAN JB, MONK M. Lysogeny in Pseudomonas aeruginosa. The Australian Journal of Experimental Biology and Medical Science. 38: 321-9. PMID 13715401  0.01
1958 RUBBO SD, ROUCH LC, EGAN JB, WADDINGTON AL, TELLESSON WG. Chemotherapy of tuberculosis. III. Verazide in the treatment of pulmonary tuberculosis. American Review of Tuberculosis. 78: 251-8. PMID 13559656  0.01
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