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Jeffrey A. Engelman, Ph.D. - Publications

Affiliations: 
2000 Yeshiva University, New York, NY, United States 
Area:
Molecular Biology, Pharmacology

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Crowe MS, Zavorotinskaya T, Voliva CF, Shirley MD, Wang Y, Ruddy DA, Rakiec DP, Engelman JA, Stuart DD, Freeman AK. RAF-mutant melanomas differentially depend on ERK2 over ERK1 to support aberrant MAPK pathway activation and cell proliferation. Molecular Cancer Research : McR. PMID 33707308 DOI: 10.1158/1541-7786.MCR-20-1022  0.329
2010 Chakrabarty A, Rexer BN, Wang SE, Cook RS, Engelman JA, Arteaga CL. H1047R phosphatidylinositol 3-kinase mutant enhances HER2-mediated transformation by heregulin production and activation of HER3 Oncogene. 29: 5193-5203. PMID 20581867 DOI: 10.1038/Onc.2010.257  0.3
2002 Razani B, Wang XB, Engelman JA, Battista M, Lagaud G, Zhang XL, Kneitz B, Hou H, Christ GJ, Edelmann W, Lisanti MP. Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae. Molecular and Cellular Biology. 22: 2329-44. PMID 11884617 DOI: 10.1128/Mcb.22.7.2329-2344.2002  0.652
2001 Razani B, Engelman JA, Wang XB, Schubert W, Zhang XL, Marks CB, Macaluso F, Russell RG, Li M, Pestell RG, Di Vizio D, Hou H, Kneitz B, Lagaud G, Christ GJ, et al. Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities. The Journal of Biological Chemistry. 276: 38121-38. PMID 11457855 DOI: 10.1074/Jbc.M105408200  0.731
2001 Lee H, Woodman SE, Engelman JA, Volonté D, Galbiati F, Kaufman HL, Lublin DM, Lisanti MP. Palmitoylation of caveolin-1 at a single site (Cys-156) controls its coupling to the c-Src tyrosine kinase: targeting of dually acylated molecules (GPI-linked, transmembrane, or cytoplasmic) to caveolae effectively uncouples c-Src and caveolin-1 (TYR-14). The Journal of Biological Chemistry. 276: 35150-8. PMID 11451957 DOI: 10.1074/Jbc.M104530200  0.675
2001 Galbiati F, Engelman JA, Volonte D, Zhang XL, Minetti C, Li M, Hou H, Kneitz B, Edelmann W, Lisanti MP. Caveolin-3 null mice show a loss of caveolae, changes in the microdomain distribution of the dystrophin-glycoprotein complex, and t-tubule abnormalities. The Journal of Biological Chemistry. 276: 21425-33. PMID 11259414 DOI: 10.1074/Jbc.M100828200  0.555
2000 Engelman JA, Berg AH, Lewis RY, Lisanti MP, Scherer PE. Tumor necrosis factor alpha-mediated insulin resistance, but not dedifferentiation, is abrogated by MEK1/2 inhibitors in 3T3-L1 adipocytes. Molecular Endocrinology (Baltimore, Md.). 14: 1557-69. PMID 11043572 DOI: 10.1210/Mend.14.10.0542  0.492
1999 Engelman JA, Berg AH, Lewis RY, Lin A, Lisanti MP, Scherer PE. Constitutively active mitogen-activated protein kinase kinase 6 (MKK6) or salicylate induces spontaneous 3T3-L1 adipogenesis. The Journal of Biological Chemistry. 274: 35630-8. PMID 10585441 DOI: 10.1074/Jbc.274.50.35630  0.494
1999 Engelman JA, Zhang XL, Razani B, Pestell RG, Lisanti MP. p42/44 MAP kinase-dependent and -independent signaling pathways regulate caveolin-1 gene expression. Activation of Ras-MAP kinase and protein kinase a signaling cascades transcriptionally down-regulates caveolin-1 promoter activity. The Journal of Biological Chemistry. 274: 32333-41. PMID 10542274 DOI: 10.1074/Jbc.274.45.32333  0.679
1999 Smart EJ, Graf GA, McNiven MA, Sessa WC, Engelman JA, Scherer PE, Okamoto T, Lisanti MP. Caveolins, liquid-ordered domains, and signal transduction. Molecular and Cellular Biology. 19: 7289-304. PMID 10523618 DOI: 10.1128/Mcb.19.11.7289  0.516
1999 Galbiati F, Volonte D, Engelman JA, Scherer PE, Lisanti MP. Targeted down-regulation of caveolin-3 is sufficient to inhibit myotube formation in differentiating C2C12 myoblasts. Transient activation of p38 mitogen-activated protein kinase is required for induction of caveolin-3 expression and subsequent myotube formation. The Journal of Biological Chemistry. 274: 30315-21. PMID 10514527 DOI: 10.1074/Jbc.274.42.30315  0.55
1999 Parolini I, Sargiacomo M, Galbiati F, Rizzo G, Grignani F, Engelman JA, Okamoto T, Ikezu T, Scherer PE, Mora R, Rodriguez-Boulan E, Peschle C, Lisanti MP. Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane. Retention of caveolin-2 at the level of the golgi complex. The Journal of Biological Chemistry. 274: 25718-25. PMID 10464309 DOI: 10.1074/Jbc.274.36.25718  0.666
1999 Engelman JA, Zhang XL, Lisanti MP. Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5' promoter region of the caveolin-1 gene in human breast cancer cell lines. Febs Letters. 448: 221-30. PMID 10218480 DOI: 10.1016/S0014-5793(99)00365-8  0.501
1999 O'Hagan R, Schreiber-Agus N, Engelman JA, Schwab R, Alland L, Thompson C, Ronning DR, Sacchettini JC, Meltzer P, DePinho RA. Identification of differentially regulated gene targets in the Myc and Mad family proteins Nature Genetics. 23: 66-66. DOI: 10.1038/14378  0.319
1998 Engelman JA, Zhang X, Galbiati F, Volonte D, Sotgia F, Pestell RG, Minetti C, Scherer PE, Okamoto T, Lisanti MP. Molecular genetics of the caveolin gene family: implications for human cancers, diabetes, Alzheimer disease, and muscular dystrophy. American Journal of Human Genetics. 63: 1578-87. PMID 9837809 DOI: 10.1086/302172  0.424
1998 Engelman JA, Lisanti MP, Scherer PE. Specific inhibitors of p38 mitogen-activated protein kinase block 3T3-L1 adipogenesis. The Journal of Biological Chemistry. 273: 32111-20. PMID 9822687 DOI: 10.1074/Jbc.273.48.32111  0.538
1998 Galbiati F, Volonte D, Engelman JA, Watanabe G, Burk R, Pestell RG, Lisanti MP. Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade. The Embo Journal. 17: 6633-48. PMID 9822607 DOI: 10.1093/Emboj/17.22.6633  0.612
1998 Engelman JA, Zhang XL, Lisanti MP. Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers. Febs Letters. 436: 403-10. PMID 9801158 DOI: 10.1016/S0014-5793(98)01134-X  0.462
1998 Schlegel A, Volonte D, Engelman JA, Galbiati F, Mehta P, Zhang XL, Scherer PE, Lisanti MP. Crowded little caves: structure and function of caveolae. Cellular Signalling. 10: 457-63. PMID 9754713 DOI: 10.1016/S0898-6568(98)00007-2  0.62
1998 Li S, Galbiati F, Volonte D, Sargiacomo M, Engelman JA, Das K, Scherer PE, Lisanti MP. Mutational analysis of caveolin-induced vesicle formation. Expression of caveolin-1 recruits caveolin-2 to caveolae membranes. Febs Letters. 434: 127-34. PMID 9738464 DOI: 10.1016/S0014-5793(98)00945-4  0.672
1998 Galbiati F, Volonte D, Gil O, Zanazzi G, Salzer JL, Sargiacomo M, Scherer PE, Engelman JA, Schlegel A, Parenti M, Okamoto T, Lisanti MP. Expression of caveolin-1 and -2 in differentiating PC12 cells and dorsal root ganglion neurons: caveolin-2 is up-regulated in response to cell injury. Proceedings of the National Academy of Sciences of the United States of America. 95: 10257-62. PMID 9707634 DOI: 10.1073/Pnas.95.17.10257  0.642
1998 Engelman JA, Lee RJ, Karnezis A, Bearss DJ, Webster M, Siegel P, Muller WJ, Windle JJ, Pestell RG, Lisanti MP. Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer. The Journal of Biological Chemistry. 273: 20448-55. PMID 9685399 DOI: 10.1074/Jbc.273.32.20448  0.613
1998 Engelman JA, Zhang XL, Galbiati F, Lisanti MP. Chromosomal localization, genomic organization, and developmental expression of the murine caveolin gene family (Cav-1, -2, and -3). Cav-1 and Cav-2 genes map to a known tumor suppressor locus (6-A2/7q31). Febs Letters. 429: 330-6. PMID 9662443 DOI: 10.1016/S0014-5793(98)00619-X  0.533
1998 Engelman JA, Chu C, Lin A, Jo H, Ikezu T, Okamoto T, Kohtz DS, Lisanti MP. Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain. Febs Letters. 428: 205-11. PMID 9654135 DOI: 10.1016/S0014-5793(98)00470-0  0.568
1997 Scherer PE, Lewis RY, Volonte D, Engelman JA, Galbiati F, Couet J, Kohtz DS, van Donselaar E, Peters P, Lisanti MP. Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo. The Journal of Biological Chemistry. 272: 29337-46. PMID 9361015 DOI: 10.1074/Jbc.272.46.29337  0.608
1997 Engelman JA, Wykoff CC, Yasuhara S, Song KS, Okamoto T, Lisanti MP. Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth. The Journal of Biological Chemistry. 272: 16374-81. PMID 9195944 DOI: 10.1074/Jbc.272.26.16374  0.591
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