Michael H. Malim - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Microbiology Biology

149 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Betancor G, Bangham M, Jeon JK, Shah K, Lynham S, Jimenez-Guardeño JM, Malim MH. MX2 Viral Substrate Breadth and Inhibitory Activity Are Regulated by Protein Phosphorylation. Mbio. e0171422. PMID 35880880 DOI: 10.1128/mbio.01714-22  0.518
2021 Khan H, Winstone H, Jimenez-Guardeño JM, Graham C, Doores KJ, Goujon C, Matthews DA, Davidson AD, Rihn SJ, Palmarini M, Neil SJD, Malim MH. TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction. Plos Pathogens. 17: e1009820. PMID 34807954 DOI: 10.1371/journal.ppat.1009820  0.342
2021 Sertkaya H, Hidalgo L, Ficarelli M, Kmiec D, Signell AW, Ali S, Parker H, Wilson H, Neil SJD, Malim MH, Vink CA, Swanson CM. Minimal impact of ZAP on lentiviral vector production and transduction efficiency. Molecular Therapy. Methods & Clinical Development. 23: 147-157. PMID 34703838 DOI: 10.1016/j.omtm.2021.08.008  0.378
2021 Betancor G, Jimenez-Guardeño JM, Lynham S, Antrobus R, Khan H, Sobala A, Dicks MDJ, Malim MH. Author Correction: MX2-mediated innate immunity against HIV-1 is regulated by serine phosphorylation. Nature Microbiology. 6: 1211. PMID 34389816 DOI: 10.1038/s41564-021-00960-6  0.324
2021 Betancor G, Jimenez-Guardeño JM, Lynham S, Antrobus R, Khan H, Sobala A, Dicks MDJ, Malim MH. MX2-mediated innate immunity against HIV-1 is regulated by serine phosphorylation. Nature Microbiology. PMID 34282309 DOI: 10.1038/s41564-021-00937-5  0.41
2021 Bauby H, Ward CC, Hugh-White R, Swanson CM, Schulz R, Goujon C, Malim MH. HIV-1 Vpr Induces Widespread Transcriptomic Changes in CD4 T Cells Early Postinfection. Mbio. e0136921. PMID 34154423 DOI: 10.1128/mBio.01369-21  0.484
2019 Betancor G, Dicks MDJ, Jimenez-Guardeño JM, Ali NH, Apolonia L, Malim MH. The GTPase Domain of MX2 Interacts with the HIV-1 Capsid, Enabling Its Short Isoform to Moderate Antiviral Restriction. Cell Reports. 29: 1923-1933.e3. PMID 31722207 DOI: 10.1016/J.Celrep.2019.10.009  0.532
2019 Jimenez-Guardeño JM, Apolonia L, Betancor G, Malim MH. Immunoproteasome activation enables human TRIM5α restriction of HIV-1. Nature Microbiology. PMID 30886358 DOI: 10.1038/S41564-019-0402-0  0.623
2019 Skelton JK, Ortega-Prieto AM, Kaye S, Jimenez-Guardeño JM, Turner J, Malim MH, Towers GJ, Dorner M. Kinetics of early innate immune activation during HIV-1 infection of humanized mice. Journal of Virology. PMID 30867315 DOI: 10.1128/Jvi.02123-18  0.565
2019 Pollpeter D, Sobala A, Malim MH. Determining 3'-Termini and Sequences of Nascent Single-Stranded Viral DNA Molecules during HIV-1 Reverse Transcription in Infected Cells. Journal of Visualized Experiments : Jove. PMID 30774124 DOI: 10.3791/58715  0.498
2019 Ng JCF, Quist J, Grigoriadis A, Malim MH, Fraternali F. Pan-cancer transcriptomic analysis dissects immune and proliferative functions of APOBEC3 cytidine deaminases. Nucleic Acids Research. PMID 30624727 DOI: 10.1093/Nar/Gky1316  0.366
2019 Malim MH, Pollpeter D. APOBEC restriction goes nuclear. Nature Microbiology. 4: 6-7. PMID 30546096 DOI: 10.1038/S41564-018-0323-3  0.471
2018 Dicks MDJ, Betancor G, Jimenez-Guardeño JM, Pessel-Vivares L, Apolonia L, Goujon C, Malim MH. Multiple components of the nuclear pore complex interact with the amino-terminus of MX2 to facilitate HIV-1 restriction. Plos Pathogens. 14: e1007408. PMID 30496303 DOI: 10.1371/Journal.Ppat.1007408  0.604
2018 Doyle T, Moncorgé O, Bonaventure B, Pollpeter D, Lussignol M, Tauziet M, Apolonia L, Catanese MT, Goujon C, Malim MH. The interferon-inducible isoform of NCOA7 inhibits endosome-mediated viral entry. Nature Microbiology. 3: 1369-1376. PMID 30478388 DOI: 10.1038/S41564-018-0273-9  0.492
2018 Vantourout P, Laing A, Woodward MJ, Zlatareva I, Apolonia L, Jones AW, Snijders AP, Malim MH, Hayday AC. Heteromeric interactions regulate butyrophilin (BTN) and BTN-like molecules governing γδ T cell biology. Proceedings of the National Academy of Sciences of the United States of America. PMID 29339503 DOI: 10.1073/Pnas.1701237115  0.338
2017 Pollpeter D, Parsons M, Sobala AE, Coxhead S, Lang RD, Bruns AM, Papaioannou S, McDonnell JM, Apolonia L, Chowdhury JA, Horvath CM, Malim MH. Deep sequencing of HIV-1 reverse transcripts reveals the multifaceted antiviral functions of APOBEC3G. Nature Microbiology. PMID 29158605 DOI: 10.1038/S41564-017-0063-9  0.611
2017 Schaller T, Bulli L, Pollpeter D, Betancor G, Kutzner J, Apolonia L, Herold N, Burk R, Malim MH. Effects of the inner nuclear membrane proteins SUN1/UNC-84A and SUN2/UNC-84B on the early steps of HIV-1 infection. Journal of Virology. PMID 28747499 DOI: 10.1128/Jvi.00463-17  0.612
2016 Bulli L, Apolonia L, Kutzner J, Pollpeter D, Goujon C, Herold N, Schwarz SM, Giernat Y, Keppler OT, Malim MH, Schaller T. Complex interplay between HIV-1 Capsid and MX2-independent IFNα-induced antiviral factors. Journal of Virology. PMID 27279606 DOI: 10.1128/Jvi.00458-16  0.613
2016 Lorenzo-Redondo R, Fryer HR, Bedford T, Kim EY, Archer J, Kosakovsky Pond SL, Chung YS, Penugonda S, Chipman JG, Fletcher CV, Schacker TW, Malim MH, Rambaut A, Haase AT, McLean AR, et al. Persistent HIV-1 replication maintains the tissue reservoir during therapy. Nature. PMID 26814962 DOI: 10.1038/Nature16933  0.568
2015 Dicks MD, Goujon C, Pollpeter D, Betancor G, Apolonia L, Bergeron JR, Malim MH. Oligomerization requirements for MX2 mediated suppression of HIV-1 infection. Journal of Virology. PMID 26446602 DOI: 10.1128/Jvi.02247-15  0.653
2015 Doyle T, Goujon C, Malim MH. HIV-1 and interferons: who's interfering with whom? Nature Reviews. Microbiology. 13: 403-13. PMID 25915633 DOI: 10.1038/Nrmicro3449  0.557
2015 Mlcochova P, Apolonia L, Kluge SF, Sridharan A, Kirchhoff F, Malim MH, Sauter D, Gupta RK. Immune evasion activities of accessory proteins Vpu, Nef and Vif are conserved in acute and chronic HIV-1 infection. Virology. 482: 72-8. PMID 25827531 DOI: 10.1016/J.Virol.2015.03.015  0.532
2015 Goujon C, Greenbury RA, Papaioannou S, Doyle T, Malim MH. A triple-arginine motif in the amino-terminal domain and oligomerization are required for HIV-1 inhibition by human MX2. Journal of Virology. 89: 4676-80. PMID 25673704 DOI: 10.1128/Jvi.00169-15  0.446
2015 Apolonia L, Schulz R, Curk T, Rocha P, Swanson CM, Schaller T, Ule J, Malim MH. Promiscuous RNA binding ensures effective encapsidation of APOBEC3 proteins by HIV-1. Plos Pathogens. 11: e1004609. PMID 25590131 DOI: 10.1371/Journal.Ppat.1004609  0.513
2015 Malim M. ID: 11 Cytokine. 76: 59. DOI: 10.1016/J.Cyto.2015.08.016  0.614
2014 Aligeti M, Behrens RT, Pocock GM, Schindelin J, Dietz C, Eliceiri KW, Swanson CM, Malim MH, Ahlquist P, Sherer NM. Cooperativity among Rev-associated nuclear export signals regulates HIV-1 gene expression and is a determinant of virus species tropism. Journal of Virology. 88: 14207-21. PMID 25275125 DOI: 10.1128/Jvi.01897-14  0.787
2014 Kim EY, Lorenzo-Redondo R, Little SJ, Chung YS, Phalora PK, Maljkovic Berry I, Archer J, Penugonda S, Fischer W, Richman DD, Bhattacharya T, Malim MH, Wolinsky SM. Human APOBEC3 induced mutation of human immunodeficiency virus type-1 contributes to adaptation and evolution in natural infection. Plos Pathogens. 10: e1004281. PMID 25080100 DOI: 10.1371/Journal.Ppat.1004281  0.588
2014 Goujon C, Moncorgé O, Bauby H, Doyle T, Barclay WS, Malim MH. Transfer of the amino-terminal nuclear envelope targeting domain of human MX2 converts MX1 into an HIV-1 resistance factor. Journal of Virology. 88: 9017-26. PMID 24899177 DOI: 10.1128/Jvi.01269-14  0.628
2014 Schaller T, Bauby H, Hué S, Malim MH, Goujon C. New insights into an X-traordinary viral protein. Frontiers in Microbiology. 5: 126. PMID 24782834 DOI: 10.3389/Fmicb.2014.00126  0.502
2014 Schaller T, Pollpeter D, Apolonia L, Goujon C, Malim MH. Nuclear import of SAMHD1 is mediated by a classical karyopherin α/β1 dependent pathway and confers sensitivity to VpxMAC induced ubiquitination and proteasomal degradation. Retrovirology. 11: 29. PMID 24712655 DOI: 10.1186/1742-4690-11-29  0.511
2014 Malim MH. HIV: Ringside views. Nature. 505: 167-8. PMID 24402277 DOI: 10.1038/505167A  0.506
2013 Lu Z, Bergeron JR, Atkinson RA, Schaller T, Veselkov DA, Oregioni A, Yang Y, Matthews SJ, Malim MH, Sanderson MR. Insight into the HIV-1 Vif SOCS-box-ElonginBC interaction. Open Biology. 3: 130100. PMID 24225024 DOI: 10.1098/Rsob.130100  0.528
2013 Goujon C, Moncorgé O, Bauby H, Doyle T, Ward CC, Schaller T, Hué S, Barclay WS, Schulz R, Malim MH. Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection. Nature. 502: 559-62. PMID 24048477 DOI: 10.1038/Nature12542  0.656
2013 Goujon C, Schaller T, Galão RP, Amie SM, Kim B, Olivieri K, Neil SJ, Malim MH. Evidence for IFNα-induced, SAMHD1-independent inhibitors of early HIV-1 infection. Retrovirology. 10: 23. PMID 23442224 DOI: 10.1186/1742-4690-10-23  0.578
2013 Gillick K, Pollpeter D, Phalora P, Kim EY, Wolinsky SM, Malim MH. Suppression of HIV-1 infection by APOBEC3 proteins in primary human CD4(+) T cells is associated with inhibition of processive reverse transcription as well as excessive cytidine deamination. Journal of Virology. 87: 1508-17. PMID 23152537 DOI: 10.1128/Jvi.02587-12  0.608
2013 Phalora P, Mahiet C, Malim M, Swanson C. Post-transcriptional control of HIV-1 Gag expression Retrovirology. 10. DOI: 10.1186/1742-4690-10-S1-P87  0.539
2012 Phalora PK, Sherer NM, Wolinsky SM, Swanson CM, Malim MH. HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies. Journal of Virology. 86: 11712-24. PMID 22915799 DOI: 10.1128/Jvi.00595-12  0.774
2012 Arjan-Odedra S, Swanson CM, Sherer NM, Wolinsky SM, Malim MH. Endogenous MOV10 inhibits the retrotransposition of endogenous retroelements but not the replication of exogenous retroviruses. Retrovirology. 9: 53. PMID 22727223 DOI: 10.1186/1742-4690-9-53  0.714
2012 Malim MH, Bieniasz PD. HIV Restriction Factors and Mechanisms of Evasion. Cold Spring Harbor Perspectives in Medicine. 2: a006940. PMID 22553496 DOI: 10.1101/Cshperspect.A006940  0.553
2012 Schaller T, Goujon C, Malim MH. AIDS/HIV. HIV interplay with SAMHD1. Science (New York, N.Y.). 335: 1313-4. PMID 22422971 DOI: 10.1126/Science.1221057  0.615
2012 Fehrholz M, Kendl S, Prifert C, Weissbrich B, Lemon K, Rennick L, Duprex PW, Rima BK, Koning FA, Holmes RK, Malim MH, Schneider-Schaulies J. The innate antiviral factor APOBEC3G targets replication of measles, mumps and respiratory syncytial viruses. The Journal of General Virology. 93: 565-76. PMID 22170635 DOI: 10.1099/Vir.0.038919-0  0.468
2011 Sherer NM, Swanson CM, Hué S, Roberts RG, Bergeron JR, Malim MH. Evolution of a species-specific determinant within human CRM1 that regulates the post-transcriptional phases of HIV-1 replication. Plos Pathogens. 7: e1002395. PMID 22114565 DOI: 10.1371/Journal.Ppat.1002395  0.79
2011 Koning FA, Goujon C, Bauby H, Malim MH. Target cell-mediated editing of HIV-1 cDNA by APOBEC3 proteins in human macrophages. Journal of Virology. 85: 13448-52. PMID 21957290 DOI: 10.1128/Jvi.00775-11  0.594
2011 Goujon C, Bauby H, Koning FA, Malim MH. Characterization of the barrier conferred by type I interferon on the early steps of HIV-1 infection in primary cells Retrovirology. 8. DOI: 10.1186/1742-4690-8-S2-P26  0.584
2011 Arjan S, Swanson C, Sherer N, Malim M. Mov10, an APOBEC3G-interacting RNA-binding protein, inhibits HIV-1 infection Retrovirology. 8. DOI: 10.1186/1742-4690-8-S2-P2  0.772
2011 Malim M. Exploiting replication deficiencies to illuminate HIV: host interactions Retrovirology. 8. DOI: 10.1186/1742-4690-8-S2-O6  0.424
2010 Kim EY, Bhattacharya T, Kunstman K, Swantek P, Koning FA, Malim MH, Wolinsky SM. Human APOBEC3G-mediated editing can promote HIV-1 sequence diversification and accelerate adaptation to selective pressure. Journal of Virology. 84: 10402-5. PMID 20660203 DOI: 10.1128/Jvi.01223-10  0.559
2010 Autore F, Bergeron JR, Malim MH, Fraternali F, Huthoff H. Rationalisation of the differences between APOBEC3G structures from crystallography and NMR studies by molecular dynamics simulations. Plos One. 5: e11515. PMID 20635000 DOI: 10.1371/Journal.Pone.0011515  0.328
2010 Goujon C, Malim MH. Characterization of the alpha interferon-induced postentry block to HIV-1 infection in primary human macrophages and T cells. Journal of Virology. 84: 9254-66. PMID 20610724 DOI: 10.1128/Jvi.00854-10  0.415
2010 Bergeron JR, Huthoff H, Veselkov DA, Beavil RL, Simpson PJ, Matthews SJ, Malim MH, Sanderson MR. The SOCS-box of HIV-1 Vif interacts with ElonginBC by induced-folding to recruit its Cul5-containing ubiquitin ligase complex. Plos Pathogens. 6: e1000925. PMID 20532212 DOI: 10.1371/Journal.Ppat.1000925  0.517
2010 Swanson CM, Sherer NM, Malim MH. SRp40 and SRp55 promote the translation of unspliced human immunodeficiency virus type 1 RNA. Journal of Virology. 84: 6748-59. PMID 20427542 DOI: 10.1128/Jvi.02526-09  0.753
2009 Koning FA, Newman EN, Kim EY, Kunstman KJ, Wolinsky SM, Malim MH. Defining APOBEC3 expression patterns in human tissues and hematopoietic cell subsets. Journal of Virology. 83: 9474-85. PMID 19587057 DOI: 10.1128/Jvi.01089-09  0.474
2009 Sherer NM, Swanson CM, Papaioannou S, Malim MH. Matrix mediates the functional link between human immunodeficiency virus type 1 RNA nuclear export elements and the assembly competency of Gag in murine cells. Journal of Virology. 83: 8525-35. PMID 19535446 DOI: 10.1128/Jvi.00699-09  0.769
2009 Huthoff H, Autore F, Gallois-Montbrun S, Fraternali F, Malim MH. RNA-dependent oligomerization of APOBEC3G is required for restriction of HIV-1. Plos Pathogens. 5: e1000330. PMID 19266078 DOI: 10.1371/Journal.Ppat.1000330  0.471
2009 Abbadessa G, Accolla R, Aiuti F, Albini A, Aldovini A, Alfano M, Antonelli G, Bartholomew C, Bentwich Z, Bertazzoni U, Berzofsky JA, Biberfeld P, Boeri E, Buonaguro L, Buonaguro FM, ... ... Malim M, et al. Unsung hero Robert C. Gallo. Science (New York, N.Y.). 323: 206-7. PMID 19131607 DOI: 10.1126/Science.323.5911.206  0.501
2009 Malim MH. APOBEC proteins and intrinsic resistance to HIV-1 infection. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 364: 675-87. PMID 19038776 DOI: 10.1098/Rstb.2008.0185  0.58
2008 Bishop KN, Verma M, Kim EY, Wolinsky SM, Malim MH. APOBEC3G inhibits elongation of HIV-1 reverse transcripts. Plos Pathogens. 4: e1000231. PMID 19057663 DOI: 10.1371/Journal.Ppat.1000231  0.573
2008 Lee YN, Malim MH, Bieniasz PD. Hypermutation of an ancient human retrovirus by APOBEC3G. Journal of Virology. 82: 8762-70. PMID 18562521 DOI: 10.1128/Jvi.00751-08  0.387
2008 Malim MH, Emerman M. HIV-1 accessory proteins--ensuring viral survival in a hostile environment. Cell Host & Microbe. 3: 388-98. PMID 18541215 DOI: 10.1016/J.Chom.2008.04.008  0.613
2008 Swanson CM, Malim MH. SnapShot: HIV-1 proteins. Cell. 133: 742, 742.e1. PMID 18485880 DOI: 10.1016/J.Cell.2008.05.005  0.461
2008 Gallois-Montbrun S, Holmes RK, Swanson CM, Fernández-Ocaña M, Byers HL, Ward MA, Malim MH. Comparison of cellular ribonucleoprotein complexes associated with the APOBEC3F and APOBEC3G antiviral proteins. Journal of Virology. 82: 5636-42. PMID 18367521 DOI: 10.1128/Jvi.00287-08  0.389
2007 Baumert TF, Rösler C, Malim MH, von Weizsäcker F. Hepatitis B virus DNA is subject to extensive editing by the human deaminase APOBEC3C. Hepatology (Baltimore, Md.). 46: 682-9. PMID 17625792 DOI: 10.1002/Hep.21733  0.372
2007 Holmes RK, Malim MH, Bishop KN. APOBEC-mediated viral restriction: not simply editing? Trends in Biochemical Sciences. 32: 118-28. PMID 17303427 DOI: 10.1016/J.Tibs.2007.01.004  0.414
2007 Huthoff H, Malim MH. Identification of amino acid residues in APOBEC3G required for regulation by human immunodeficiency virus type 1 Vif and Virion encapsidation. Journal of Virology. 81: 3807-15. PMID 17267497 DOI: 10.1128/Jvi.02795-06  0.476
2007 Gallois-Montbrun S, Kramer B, Swanson CM, Byers H, Lynham S, Ward M, Malim MH. Antiviral protein APOBEC3G localizes to ribonucleoprotein complexes found in P bodies and stress granules. Journal of Virology. 81: 2165-78. PMID 17166910 DOI: 10.1128/Jvi.02287-06  0.384
2007 Holmes RK, Koning FA, Bishop KN, Malim MH. APOBEC3F can inhibit the accumulation of HIV-1 reverse transcription products in the absence of hypermutation. Comparisons with APOBEC3G. The Journal of Biological Chemistry. 282: 2587-95. PMID 17121840 DOI: 10.1074/Jbc.M607298200  0.545
2006 Malim MH. Natural resistance to HIV infection: The Vif-APOBEC interaction. Comptes Rendus Biologies. 329: 871-5. PMID 17067930 DOI: 10.1016/J.Crvi.2006.01.012  0.588
2006 Swanson CM, Malim MH. Retrovirus RNA trafficking: from chromatin to invasive genomes. Traffic (Copenhagen, Denmark). 7: 1440-50. PMID 16984406 DOI: 10.1111/J.1600-0854.2006.00488.X  0.454
2006 Bishop KN, Holmes RK, Malim MH. Antiviral potency of APOBEC proteins does not correlate with cytidine deamination. Journal of Virology. 80: 8450-8. PMID 16912295 DOI: 10.1128/Jvi.00839-06  0.594
2005 Rösler C, Köck J, Kann M, Malim MH, Blum HE, Baumert TF, von Weizsäcker F. APOBEC-mediated interference with hepadnavirus production. Hepatology (Baltimore, Md.). 42: 301-9. PMID 16025511 DOI: 10.1002/Hep.20801  0.551
2005 Huthoff H, Malim MH. Cytidine deamination and resistance to retroviral infection: towards a structural understanding of the APOBEC proteins. Virology. 334: 147-53. PMID 15780864 DOI: 10.1016/J.Virol.2005.01.038  0.471
2005 Newman EN, Holmes RK, Craig HM, Klein KC, Lingappa JR, Malim MH, Sheehy AM. Antiviral function of APOBEC3G can be dissociated from cytidine deaminase activity. Current Biology : Cb. 15: 166-70. PMID 15668174 DOI: 10.1016/J.Cub.2004.12.068  0.467
2004 Gaddis NC, Sheehy AM, Ahmad KM, Swanson CM, Bishop KN, Beer BE, Marx PA, Gao F, Bibollet-Ruche F, Hahn BH, Malim MH. Further investigation of simian immunodeficiency virus Vif function in human cells. Journal of Virology. 78: 12041-6. PMID 15479843 DOI: 10.1128/Jvi.78.21.12041-12046.2004  0.772
2004 Rösler C, Köck J, Malim MH, Blum HE, von Weizsäcker F. Comment on "Inhibition of hepatitis B virus replication by APOBEC3G". Science (New York, N.Y.). 305: 1403; author reply 1. PMID 15353783 DOI: 10.1126/Science.1100464  0.444
2004 Bishop KN, Holmes RK, Sheehy AM, Davidson NO, Cho SJ, Malim MH. Cytidine deamination of retroviral DNA by diverse APOBEC proteins. Current Biology : Cb. 14: 1392-6. PMID 15296758 DOI: 10.1016/J.Cub.2004.06.057  0.618
2004 Bishop KN, Holmes RK, Sheehy AM, Malim MH. APOBEC-mediated editing of viral RNA. Science (New York, N.Y.). 305: 645. PMID 15286366 DOI: 10.1126/Science.1100658  0.521
2004 Swanson CM, Puffer BA, Ahmad KM, Doms RW, Malim MH. Retroviral mRNA nuclear export elements regulate protein function and virion assembly. The Embo Journal. 23: 2632-40. PMID 15201866 DOI: 10.1038/Sj.Emboj.7600270  0.558
2004 Swiggard WJ, O'Doherty U, McGain D, Jeyakumar D, Malim MH. Long HIV type 1 reverse transcripts can accumulate stably within resting CD4+ T cells while short ones are degraded. Aids Research and Human Retroviruses. 20: 285-95. PMID 15117452 DOI: 10.1089/088922204322996527  0.488
2004 Harris RS, Bishop KN, Sheehy AM, Craig HM, Petersen-Mahrt SK, Watt IN, Neuberger MS, Malim MH. Erratum: DNA Deamination Mediates Innate Immunity to Retroviral Infection (Cell (June 13, 2003) 113 (803-809)) Cell. 116. DOI: 10.1016/S0092-8674(04)00163-1  0.331
2003 Sheehy AM, Gaddis NC, Malim MH. The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif. Nature Medicine. 9: 1404-7. PMID 14528300 DOI: 10.1038/Nm945  0.814
2003 Dvorin JD, Malim MH. Intracellular trafficking of HIV-1 cores: journey to the center of the cell. Current Topics in Microbiology and Immunology. 281: 179-208. PMID 12932078 DOI: 10.1007/978-3-642-19012-4_5  0.795
2003 Harris RS, Bishop KN, Sheehy AM, Craig HM, Petersen-Mahrt SK, Watt IN, Neuberger MS, Malim MH. DNA deamination mediates innate immunity to retroviral infection. Cell. 113: 803-9. PMID 12809610 DOI: 10.1016/S0092-8674(03)00423-9  0.607
2003 Gaddis NC, Chertova E, Sheehy AM, Henderson LE, Malim MH. Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions. Journal of Virology. 77: 5810-20. PMID 12719574 DOI: 10.1128/Jvi.77.10.5810-5820.2003  0.813
2002 Dvorin JD, Bell P, Maul GG, Yamashita M, Emerman M, Malim MH. Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import. Journal of Virology. 76: 12087-96. PMID 12414950 DOI: 10.1128/Jvi.76.23.12087-12096.2002  0.81
2002 O'Doherty U, Swiggard WJ, Jeyakumar D, McGain D, Malim MH. A sensitive, quantitative assay for human immunodeficiency virus type 1 integration. Journal of Virology. 76: 10942-50. PMID 12368337 DOI: 10.1128/Jvi.76.21.10942-10950.2002  0.564
2002 Sheehy AM, Gaddis NC, Choi JD, Malim MH. Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature. 418: 646-50. PMID 12167863 DOI: 10.1038/Nature00939  0.818
2002 Schang LM, Bantly A, Knockaert M, Shaheen F, Meijer L, Malim MH, Gray NS, Schaffer PA. Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 by targeting cellular, not viral, proteins. Journal of Virology. 76: 7874-82. PMID 12097601 DOI: 10.1128/Jvi.76.15.7874-7882.2002  0.569
2001 Lee B, Leslie G, Soilleux E, O'Doherty U, Baik S, Levroney E, Flummerfelt K, Swiggard W, Coleman N, Malim M, Doms RW. cis expression of DC-SIGN allows for more efficient entry of human and simian immunodeficiency viruses via CD4 and a coreceptor Journal of Virology. 75: 12028-12038. PMID 11711593 DOI: 10.1128/Jvi.75.24.12028-12038.2001  0.479
2001 Jenkins Y, Pornillos O, Rich RL, Myszka DG, Sundquist WI, Malim MH. Biochemical analyses of the interactions between human immunodeficiency virus type 1 Vpr and p6(Gag). Journal of Virology. 75: 10537-42. PMID 11581428 DOI: 10.1128/Jvi.75.21.10537-10542.2001  0.451
2001 Jenkins Y, Sanchez PV, Meyer BE, Malim MH. Nuclear export of human immunodeficiency virus type 1 Vpr is not required for virion packaging. Journal of Virology. 75: 8348-52. PMID 11483780 DOI: 10.1128/Jvi.75.17.8348-8352.2001  0.752
2001 Bouyac-Bertoia M, Dvorin JD, Fouchier RA, Jenkins Y, Meyer BE, Wu LI, Emerman M, Malim MH. HIV-1 infection requires a functional integrase NLS. Molecular Cell. 7: 1025-35. PMID 11389849 DOI: 10.1016/S1097-2765(01)00240-4  0.799
2001 Means RE, Matthews T, Hoxie JA, Malim MH, Kodama T, Desrosiers RC. Ability of the V3 loop of simian immunodeficiency virus to serve as a target for antibody-mediated neutralization: correlation of neutralization sensitivity, growth in macrophages, and decreased dependence on CD4. Journal of Virology. 75: 3903-15. PMID 11264379 DOI: 10.1128/Jvi.75.8.3903-3915.2001  0.375
2001 Malim MH, Emerman M. HIV-1 sequence variation: drift, shift, and attenuation. Cell. 104: 469-72. PMID 11239404 DOI: 10.1016/S0092-8674(01)00234-3  0.511
2001 Fultz PN, Vance PJ, Endres MJ, Tao B, Dvorin JD, Davis IC, Lifson JD, Montefiori DC, Marsh M, Malim MH, Hoxie JA. In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail. Journal of Virology. 75: 278-91. PMID 11119598 DOI: 10.1128/Jvi.75.1.278-291.2001  0.742
2000 O'Doherty U, Swiggard WJ, Malim MH. Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding Journal of Virology. 74: 10074-10080. PMID 11024136 DOI: 10.1128/Jvi.74.21.10074-10080.2000  0.581
2000 Alexander L, Weiskopf E, Greenough TC, Gaddis NC, Auerbach MR, Malim MH, O'Brien SJ, Walker BD, Sullivan JL, Desrosiers RC. Unusual polymorphisms in human immunodeficiency virus type 1 associated with nonprogressive infection. Journal of Virology. 74: 4361-76. PMID 10756051 DOI: 10.1128/Jvi.74.9.4361-4376.2000  0.78
2000 Shieh JTC, Martín J, Baltuch G, Malim MH, González-Scarano F. Determinants of syncytium formation in microglia by human immunodeficiency virus type 1: Role of the V1/V2 domains Journal of Virology. 74: 693-701. PMID 10623731 DOI: 10.1128/Jvi.74.2.693-701.2000  0.557
1999 Fischer U, Pollard VW, Lührmann R, Teufel M, Michael MW, Dreyfuss G, Malim MH. Rev-mediated nuclear export of RNA is dominant over nuclear retention and is coupled to the Ran-GTPase cycle. Nucleic Acids Research. 27: 4128-34. PMID 10518602 DOI: 10.1093/Nar/27.21.4128  0.425
1999 Fouchier RA, Malim MH. Nuclear import of human immunodeficiency virus type-1 preintegration complexes Advances in Virus Research. 52: 275-299. PMID 10384238 DOI: 10.1016/S0065-3527(08)60302-4  0.576
1999 Simon JHM, Sheehy AM, Carpenter EA, Fouchier RAM, Malim MH. Mutational analysis of the human immunodeficiency virus type 1 Vif protein Journal of Virology. 73: 2675-2681. PMID 10074113 DOI: 10.1128/Jvi.73.4.2675-2681.1999  0.565
1999 Simon JHM, Carpenter EA, Fouchier RAM, Malim MH. Vif and the p55(Gag) polyprotein of human immunodeficiency virus type 1 are present in colocalizing membrane-free cytoplasmic complexes Journal of Virology. 73: 2667-2674. PMID 10074112 DOI: 10.1128/Jvi.73.4.2667-2674.1999  0.558
1999 Pollard VW, Malim MH. The HIV-1 Rev protein. Annual Review of Microbiology. 52: 491-532. PMID 9891806 DOI: 10.1146/Annurev.Micro.52.1.491  0.54
1999 Palmeri D, Malim MH. Importin β can mediate the nuclear import of an arginine-rich nuclear localization signal in the absence of importin α Molecular and Cellular Biology. 19: 1218-1225. PMID 9891056 DOI: 10.1128/Mcb.19.2.1218  0.323
1998 Simon JH, Gaddis NC, Fouchier RA, Malim MH. Evidence for a newly discovered cellular anti-HIV-1 phenotype. Nature Medicine. 4: 1397-400. PMID 9846577 DOI: 10.1038/3987  0.819
1998 Simon JHM, Miller DL, Fouchier RAM, Malim MH. Virion incorporation of human immunodeficiency virus type-1 Vif is determined by intracellular expression level and may not be necessary for function Virology. 248: 182-187. PMID 9721227 DOI: 10.1006/Viro.1998.9296  0.596
1998 Elder JH, Dean GA, Hoover EA, Hoxie JA, Malim MH, Mathes L, Neil JC, North TW, Sparger E, Tompkins MB, Tompkins WA, Yamamoto J, Yuhki N, Pedersen NC, Miller RH. Lessons from the cat: feline immunodeficiency virus as a tool to develop intervention strategies against human immunodeficiency virus type 1. Aids Research and Human Retroviruses. 14: 797-801. PMID 9643379 DOI: 10.1089/Aid.1998.14.797  0.34
1998 Emerman M, Malim MH. HIV-1 regulatory/accessory genes: keys to unraveling viral and host cell biology. Science (New York, N.Y.). 280: 1880-4. PMID 9632380 DOI: 10.1126/Science.280.5371.1880  0.627
1998 Fouchier RA, Meyer BE, Simon JH, Fischer U, Albright AV, González-Scarano F, Malim MH. Interaction of the human immunodeficiency virus type 1 Vpr protein with the nuclear pore complex. Journal of Virology. 72: 6004-13. PMID 9621063 DOI: 10.1128/Jvi.72.7.6004-6013.1998  0.551
1998 Simon JHM, Miller DL, Fouchier RAM, Soares MA, Peden KWC, Malim MH. The regulation of primate immunodeficiency virus infectivity by Vif is cell species restricted: A role for Vif in determining virus host range and cross-species transmission Embo Journal. 17: 1259-1267. PMID 9482723 DOI: 10.1093/Emboj/17.5.1259  0.647
1997 Fouchier RAM, Meyer BE, Simon JHM, Fischer U, Malim MH. HIV-1 infection of non-dividing cells: Evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import Embo Journal. 16: 4531-4539. PMID 9303297 DOI: 10.1093/Emboj/16.15.4531  0.62
1997 Simon JHM, Fouchier RAM, Southerling TE, Guerra CB, Grant CK, Malim MH. The Vif and Gag proteins of human immunodeficiency virus type 1 colocalize in infected human T cells Journal of Virology. 71: 5259-5267. PMID 9188594 DOI: 10.1128/Jvi.71.7.5259-5267.1997  0.611
1996 Fouchier RAM, Simon JHM, Jaffe AB, Malim MH. Human immunodeficiency virus type 1 Vif does not influence expression or virion incorporation of gag-, pol-, and env-encoded proteins Journal of Virology. 70: 8263-8269. PMID 8970945 DOI: 10.1128/Jvi.70.12.8263-8269.1996  0.545
1996 Simon JHM, Malim MH. The human immunodeficiency virus type 1 vif protein modulates the postpenetration stability of viral nucleoprotein complexes Journal of Virology. 70: 5297-5305. PMID 8764040 DOI: 10.1128/Jvi.70.8.5297-5305.1996  0.532
1996 Palmeri D, Malim MH. The human T-cell leukemia virus type 1 posttranscriptional trans- activator Rex contains a nuclear export signal Journal of Virology. 70: 6442-6445. PMID 8709278 DOI: 10.1128/Jvi.70.9.6442-6445.1996  0.497
1996 Meyer BE, Meinkoth JL, Malim MH. Nuclear transport of human immunodeficiency virus type 1, visna virus, and equine infectious anemia virus Rev proteins: Identification of a family of transferable nuclear export signals Journal of Virology. 70: 2350-2359. PMID 8642662 DOI: 10.1128/Jvi.70.4.2350-2359.1996  0.493
1996 Fridell RA, Fischer U, Lührmann R, Meyer BE, Meinkoth JL, Malim MH, Cullen BR. Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 rev Proceedings of the National Academy of Sciences of the United States of America. 93: 2936-2940. PMID 8610146 DOI: 10.1073/Pnas.93.7.2936  0.585
1995 Simon JHM, Southerling TE, Peterson JC, Meyer BE, Malim MH. Complementation of vif-defective human immunodeficiency virus type 1 by primate, but not nonprimate, lentivirus vif genes Journal of Virology. 69: 4166-4172. PMID 7769676 DOI: 10.1128/Jvi.69.7.4166-4172.1995  0.511
1994 Meyer BE, Malim MH. The HIV-1 Rev trans-activator shuttles between the nucleus and the cytoplasm Genes and Development. 8: 1538-1547. PMID 7958838 DOI: 10.1101/Gad.8.13.1538  0.549
1994 Hammerschmid M, Palmeri D, Ruhl M, Jaksche H, Weichselbraun I, Böhnlein E, Malim MH, Hauber J. Scanning mutagenesis of the arginine-rich region of the human immunodeficiency virus type 1 Rev trans activator Journal of Virology. 68: 7329-7335. PMID 7523698 DOI: 10.1128/Jvi.68.11.7329-7335.1994  0.495
1994 Madore SJ, Tiley LS, Malim MH, Cullen BR. Sequence Requirements for Rev Multimerization in Vivo Virology. 202: 186-194. PMID 7516596 DOI: 10.1006/Viro.1994.1334  0.503
1993 Malim MH, Cullen BR. Rev and the fate of pre-mRNA in the nucleus: Implications for the regulation of RNA processing in eukaryotes Molecular and Cellular Biology. 13: 6180-6189. PMID 8105371 DOI: 10.1128/Mcb.13.10.6180  0.5
1992 Tiley LS, Malim MH, Tewary HK, Stockley PG, Cullen BR. Identification of a high-affinity RNA-binding site for the human immunodeficiency virus type 1 Rev protein. Proceedings of the National Academy of Sciences of the United States of America. 89: 758-62. PMID 1731351 DOI: 10.1073/Pnas.89.2.758  0.4
1992 Chen H, Boyle TJ, Malim MH, Cullen BR, Lyerly HK. Derivation of a biologically contained replication system for human immunodeficiency virus type 1 Proceedings of the National Academy of Sciences of the United States of America. 89: 7678-7682. PMID 1502183 DOI: 10.1073/Pnas.89.16.7678  0.641
1992 Tiley LS, Madore SJ, Malim MH, Cullen BR. The VP16 transcription activation domain is functional when targeted to a promoter-proximal RNA sequence Genes and Development. 6: 2077-2087. PMID 1427073 DOI: 10.1101/Gad.6.11.2077  0.569
1992 Malim MH, Freimuth WW, Liu J, Boyle TJ, Lyerly HK, Cullen BR, Nabel GJ. Stable expression of transdominant rev protein in human T cells inhibits human immunodeficiency virus replication Journal of Experimental Medicine. 176: 1197-1201. PMID 1402661 DOI: 10.1084/Jem.176.4.1197  0.622
1991 Malim MH, McCarn DF, Tiley LS, Cullen BR. Mutational definition of the human immunodeficiency virus type 1 Rev activation domain Journal of Virology. 65: 4248-4254. PMID 2072452 DOI: 10.1128/Jvi.65.8.4248-4254.1991  0.512
1991 Malim MH, Cullen BR. HIV-1 structural gene expression requires the binding of multiple Rev monomers to the viral RRE: Implications for HIV-1 latency Cell. 65: 241-248. PMID 2015625 DOI: 10.1016/0092-8674(91)90158-U  0.564
1991 Cullen BR, Malim MH. The HIV-1 Rev protein: prototype of a novel class of eukaryotic post-transcriptional regulators Trends in Biochemical Sciences. 16: 346-350. PMID 1949157 DOI: 10.1016/0968-0004(91)90141-H  0.629
1991 Weinberg JB, Matthews TJ, Cullen BR, Malim MH. Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes Journal of Experimental Medicine. 174: 1477-1482. PMID 1720811 DOI: 10.1084/Jem.174.6.1477  0.579
1991 Tiley LS, Malim MH, Cullen BR. Conserved functional organization of the human immunodeficiency virus type 1 and visna virus Rev proteins Journal of Virology. 65: 3877-3881. PMID 1645796 DOI: 10.1128/Jvi.65.7.3877-3881.1991  0.503
1990 Malim MH, Tiley LS, McCarn DF, Rusche JR, Hauber J, Cullen BR. HIV-1 structural gene expression requires binding of the rev trans-activator to its RNA target sequence Cell. 60: 675-683. PMID 2406030 DOI: 10.1016/0092-8674(90)90670-A  0.51
1990 Le SY, Malim MH, Cullen BR, Maizel JV. A highly conserved RNA folding region coincident with the Rev response element of primate immunodeficiency viruses Nucleic Acids Research. 18: 1613-1623. PMID 2326200 DOI: 10.1093/Nar/18.6.1613  0.565
1990 Ahmed YF, Hanly SM, Malim MH, Cullen BR, Greene WC. Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: Insights into the mechanism of Rex and Rev action Genes and Development. 4: 1014-1022. PMID 2116986 DOI: 10.1101/Gad.4.6.1014  0.543
1989 Malim MH, Hauber J, Le SY, Maizel JV, Cullen BR. The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA Nature. 338: 254-257. PMID 2784194 DOI: 10.1038/338254A0  0.608
1989 Malim MH, Böhnlein S, Hauber J, Cullen BR. Functional dissection of the HIV-1 Rev trans-activator-Derivation of a trans-dominant repressor of Rev function Cell. 58: 205-214. PMID 2752419 DOI: 10.1016/0092-8674(89)90416-9  0.623
1989 Hammes SR, Dixon EP, Malim MH, Cullen BR, Greene WC. Nef protein of human immunodeficiency virus type 1: Evidence against its role as a transcriptional inhibitor Proceedings of the National Academy of Sciences of the United States of America. 86: 9549-9553. PMID 2687884 DOI: 10.1073/Pnas.86.23.9549  0.637
1989 Malim MH, Bohnlein S, Fenrick R, Le SY, Maizel JV, Cullen BR. Functional comparison of the Rev trans-activators encoded by different primate immunodeficiency virus species Proceedings of the National Academy of Sciences of the United States of America. 86: 8222-8226. PMID 2682638 DOI: 10.1073/Pnas.86.21.8222  0.632
1989 Fenrick R, Malim MH, Hauber J, Le SY, Maizel J, Cullen BR. Functional analysis of the Tat trans activator of human immunodeficiency virus type 2 Journal of Virology. 63: 5006-5012. PMID 2555537 DOI: 10.1128/Jvi.63.12.5006-5012.1989  0.593
1989 Malim MH, Fenrick R, Ballard DW, Hauber J, Bohnlein E, Cullen BR. Functional characterization of a complex protein-DNA-binding domain located within the human immunodeficiency virus type 1 long terminal repeat leader region Journal of Virology. 63: 3213-3219. PMID 2545899 DOI: 10.1128/Jvi.63.8.3213-3219.1989  0.542
1989 Hauber J, Malim MH, Cullen BR. Mutational analysis of the conserved basic domain of human immunodeficiency virus tat protein Journal of Virology. 63: 1181-1187. PMID 2536828 DOI: 10.1128/Jvi.63.3.1181-1187.1989  0.515
1989 Hanly SM, Rimsky LT, Malim MH, Kim JH, Hauber J, Duc Dodon M, Le SY, Maizel JV, Cullen BR, Greene WC. Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements Genes &Amp; Development. 3: 1534-1544. PMID 2482226 DOI: 10.1101/Gad.3.10.1534  0.566
1988 Malim MH, Hauber J, Fenrick R, Cullen BR. Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes Nature. 335: 181-183. PMID 3412474 DOI: 10.1038/335181A0  0.611
1988 Rimsky L, Hauber J, Dukovich M, Malim MH, Langlois A, Cullen BR, Greene WC. Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein Nature. 335: 738-740. PMID 3262832 DOI: 10.1038/335738A0  0.635
1988 Adams SE, Rathjen PD, Stanway CA, Fulton SM, Malim MH, Wilson W, Ogden J, King L, Kingsman SM, Kingsman AJ. Complete nucleotide sequence of a mouse VL30 retro-element. Molecular and Cellular Biology. 8: 2989-98. PMID 2850474 DOI: 10.1128/Mcb.8.8.2989  0.372
1988 Hauber J, Bouvier M, Malim MH, Cullen BR. Phosphorylation of the rev gene product of human immunodeficiency virus type 1 Journal of Virology. 62: 4801-4804. PMID 2846891 DOI: 10.1128/Jvi.62.12.4801-4804.1988  0.475
1987 Kingsman AJ, Mellor J, Adams S, Rathjen PD, Malim MH, Fulton SM, Wilson W, Kingsman SM. The genetic organization of the yeast Ty element. Journal of Cell Science. Supplement. 7: 155-67. PMID 2846592 DOI: 10.1242/Jcs.1987.Supplement_7.12  0.41
1987 Malim MH, Adams SE, Gull K, Kingsman AJ, Kingsman SM. The productton of hybrid ty: IFN virus-like particles in yeast Nucleic Acids Research. 15: 7571-7580. PMID 2821510 DOI: 10.1093/Nar/15.18.7571  0.404
1986 Wilson W, Malim MH, Mellor J, Kingsman AJ, Kingsman SM. Expression strategies of the yeast retrotransposon ty: A short sequence directs ribosomal frameshifting Nucleic Acids Research. 14: 7001-7016. PMID 3020502 DOI: 10.1093/Nar/14.17.7001  0.383
1985 Mellor J, Malim MH, Gull K, Tuite MF, McCready S, Dibbayawan T, Kingsman SM, Kingsman AJ. Reverse transcriptase activity and Ty RNA are associated with virus-like particles in yeast Nature. 318: 583-586. PMID 2415827 DOI: 10.1038/318583A0  0.459
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