Ernst Hafen - Publications

ETH Zürich, Zürich, ZH, Switzerland 
growth control

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Edmunds LD, Gluderer S, Ovseiko PV, Kamerling R, Ton J, Vis L, Jenni M, Tutton G, Lawton-Smith H, Nadabán MV, Rab M, Rees J, Anson J, Rushforth AD, Allen M, ... ... Hafen E, et al. New indicators and indexes for benchmarking university-industry-government innovation in medical and life science clusters: results from the European FP7 Regions of Knowledge HealthTIES project. Health Research Policy and Systems. 17: 10. PMID 30691504 DOI: 10.1186/S12961-019-0414-5  1
2016 Lujan E, Bornemann DJ, Rottig C, Bayless BA, Stocker H, Hafen E, Arora K, Warrior R. Analysis of novel alleles of brother of tout-velu, the Drosophila ortholog of human EXTL3 using a newly developed FRT42D ovo(D) chromosome. Genesis (New York, N.Y. : 2000). PMID 27636555 DOI: 10.1002/Dvg.22981  1
2016 Okada H, Ebhardt HA, Vonesch SC, Aebersold R, Hafen E. Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster. Nature Communications. 7: 12649. PMID 27582081 DOI: 10.1038/Ncomms12649  1
2016 Vonesch SC, Lamparter D, Mackay TF, Bergmann S, Hafen E. Genome-Wide Analysis Reveals Novel Regulators of Growth in Drosophila melanogaster. Plos Genetics. 12: e1005616. PMID 26751788 DOI: 10.1371/Journal.Pgen.1005616  1
2015 Jevtov I, Zacharogianni M, van Oorschot MM, van Zadelhoff G, Aguilera-Gomez A, Vuillez I, Braakman I, Hafen E, Stocker H, Rabouille C. TORC2 mediates the heat stress response in Drosophila by promoting the formation of stress granules. Journal of Cell Science. 128: 2497-508. PMID 26054799 DOI: 10.1242/Jcs.168724  1
2014 Ozdemir V, Endrenyi L, Aynacıoğlu S, Bragazzi NL, Dandara C, Dove ES, Ferguson LR, Geraci CJ, Hafen E, Kesim BE, Kolker E, Lee EJ, Llerena A, Nacak M, Shimoda K, et al. Bernard Lerer: recipient of the 2014 inaugural Werner Kalow Responsible Innovation Prize in Global Omics and Personalized Medicine (Pacific Rim Association for Clinical Pharmacogenetics). Omics : a Journal of Integrative Biology. 18: 211-21. PMID 24649998 DOI: 10.1089/omi.2014.0029  1
2014 Hafen E, Kossmann D, Brand A. Health data cooperatives - citizen empowerment. Methods of Information in Medicine. 53: 82-6. PMID 24514946 DOI: 10.3414/Me13-02-0051  1
2013 Baumgartner R, Stocker H, Hafen E. The RNA-binding proteins FMR1, rasputin and caprin act together with the UBA protein lingerer to restrict tissue growth in Drosophila melanogaster. Plos Genetics. 9: e1003598. PMID 23874212 DOI: 10.1371/Journal.Pgen.1003598  1
2013 Nowak K, Seisenbacher G, Hafen E, Stocker H. Nutrient restriction enhances the proliferative potential of cells lacking the tumor suppressor PTEN in mitotic tissues. Elife. 2: e00380. PMID 23853709 DOI: 10.7554/Elife.00380  1
2013 Handke B, Poernbacher I, Goetze S, Ahrens CH, Omasits U, Marty F, Simigdala N, Meyer I, Wollscheid B, Brunner E, Hafen E, Lehner CF. The hemolymph proteome of fed and starved Drosophila larvae. Plos One. 8: e67208. PMID 23840627 DOI: 10.1371/Journal.Pone.0067208  1
2013 Sarraf-Zadeh L, Christen S, Sauer U, Cognigni P, Miguel-Aliaga I, Stocker H, Köhler K, Hafen E. Local requirement of the Drosophila insulin binding protein imp-L2 in coordinating developmental progression with nutritional conditions. Developmental Biology. 381: 97-106. PMID 23773803 DOI: 10.1016/J.Ydbio.2013.06.008  1
2013 Bader R, Sarraf-Zadeh L, Peters M, Moderau N, Stocker H, Köhler K, Pankratz MJ, Hafen E. The IGFBP7 homolog Imp-L2 promotes insulin signaling in distinct neurons of the Drosophila brain. Journal of Cell Science. 126: 2571-6. PMID 23591813 DOI: 10.1242/Dev.100065  1
2013 Almudi I, Poernbacher I, Hafen E, Stocker H. The Lnk/SH2B adaptor provides a fail-safe mechanism to establish the Insulin receptor-Chico interaction. Cell Communication and Signaling : Ccs. 11: 26. PMID 23590848 DOI: 10.1186/1478-811X-11-26  1
2012 Vayena E, Gourna E, Streuli J, Hafen E, Prainsack B. Experiences of early users of direct-to-consumer genomics in Switzerland: an exploratory study. Public Health Genomics. 15: 352-62. PMID 23154382 DOI: 10.1159/000343792  1
2011 Glatter T, Schittenhelm RB, Rinner O, Roguska K, Wepf A, Jünger MA, Köhler K, Jevtov I, Choi H, Schmidt A, Nesvizhskii AI, Stocker H, Hafen E, Aebersold R, Gstaiger M. Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome. Molecular Systems Biology. 7: 547. PMID 22068330 DOI: 10.1038/Msb.2011.79  1
2011 Seisenbacher G, Hafen E, Stocker H. MK2-dependent p38b signalling protects Drosophila hindgut enterocytes against JNK-induced apoptosis under chronic stress. Plos Genetics. 7: e1002168. PMID 21829386 DOI: 10.1371/Journal.Pgen.1002168  1
2011 Kim Y, Paroush Z, Nairz K, Hafen E, Jiménez G, Shvartsman SY. Substrate-dependent control of MAPK phosphorylation in vivo. Molecular Systems Biology. 7: 467. PMID 21283143 DOI: 10.1038/Msb.2010.121  1
2011 Barth JM, Szabad J, Hafen E, Köhler K. Autophagy in Drosophila ovaries is induced by starvation and is required for oogenesis. Cell Death and Differentiation. 18: 915-24. PMID 21151027 DOI: 10.1038/Cdd.2010.157  1
2010 Montagne J, Lecerf C, Parvy JP, Bennion JM, Radimerski T, Ruhf ML, Zilbermann F, Vouilloz N, Stocker H, Hafen E, Kozma SC, Thomas G. The nuclear receptor DHR3 modulates dS6 kinase-dependent growth in Drosophila. Plos Genetics. 6: e1000937. PMID 20463884 DOI: 10.1371/Journal.Pgen.1000937  1
2010 Slack C, Werz C, Wieser D, Alic N, Foley A, Stocker H, Withers DJ, Thornton JM, Hafen E, Partridge L. Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. Plos Genetics. 6: e1000881. PMID 20333234 DOI: 10.1371/Journal.Pgen.1000881  1
2010 Baumgartner R, Poernbacher I, Buser N, Hafen E, Stocker H. The WW domain protein Kibra acts upstream of Hippo in Drosophila. Developmental Cell. 18: 309-16. PMID 20159600 DOI: 10.1016/J.Devcel.2009.12.013  1
2010 Gluderer S, Brunner E, Germann M, Jovaisaite V, Li C, Rentsch CA, Hafen E, Stocker H. Madm (Mlf1 adapter molecule) cooperates with Bunched A to promote growth in Drosophila. Journal of Biology. 9: 9. PMID 20149264 DOI: 10.1186/Jbiol216  1
2010 Aegerter-Wilmsen T, Smith AC, Christen AJ, Aegerter CM, Hafen E, Basler K. Exploring the effects of mechanical feedback on epithelial topology. Development (Cambridge, England). 137: 499-506. PMID 20081194 DOI: 10.1242/Dev.041731  1
2009 Goetze S, Qeli E, Mosimann C, Staes A, Gerrits B, Roschitzki B, Mohanty S, Niederer EM, Laczko E, Timmerman E, Lange V, Hafen E, Aebersold R, Vandekerckhove J, Basler K, et al. Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster. Plos Biology. 7: e1000236. PMID 19885390 DOI: 10.1371/Journal.Pbio.1000236  1
2009 Werz C, Köhler K, Hafen E, Stocker H. The Drosophila SH2B family adaptor Lnk acts in parallel to chico in the insulin signaling pathway. Plos Genetics. 5: e1000596. PMID 19680438 DOI: 10.1371/Journal.Pgen.1000596  1
2009 Köhler K, Brunner E, Guan XL, Boucke K, Greber UF, Mohanty S, Barth JM, Wenk MR, Hafen E. A combined proteomic and genetic analysis identifies a role for the lipid desaturase Desat1 in starvation-induced autophagy in Drosophila. Autophagy. 5: 980-90. PMID 19587536 DOI: 10.4161/Auto.5.7.9325  1
2009 Loevenich SN, Brunner E, King NL, Deutsch EW, Stein SE, Aebersold R, Hafen E. The Drosophila melanogaster PeptideAtlas facilitates the use of peptide data for improved fly proteomics and genome annotation. Bmc Bioinformatics. 10: 59. PMID 19210778 DOI: 10.1186/1471-2105-10-59  1
2009 Almudi I, Stocker H, Hafen E, Corominas M, Serras F. SOCS36E specifically interferes with Sevenless signaling during Drosophila eye development. Developmental Biology. 326: 212-23. PMID 19083999 DOI: 10.1016/J.Ydbio.2008.11.014  1
2008 Honegger B, Galic M, Köhler K, Wittwer F, Brogiolo W, Hafen E, Stocker H. Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance. Journal of Biology. 7: 10. PMID 18412985 DOI: 10.1186/Jbiol72  1
2008 Wu X, Yamada-Mabuchi M, Morris EJ, Tanwar PS, Dobens L, Gluderer S, Khan S, Cao J, Stocker H, Hafen E, Dyson NJ, Raftery LA. The Drosophila homolog of human tumor suppressor TSC-22 promotes cellular growth, proliferation, and survival. Proceedings of the National Academy of Sciences of the United States of America. 105: 5414-9. PMID 18375761 DOI: 10.1073/Pnas.0800945105  1
2008 Gluderer S, Oldham S, Rintelen F, Sulzer A, Schütt C, Wu X, Raftery LA, Hafen E, Stocker H. Bunched, the Drosophila homolog of the mammalian tumor suppressor TSC-22, promotes cellular growth. Bmc Developmental Biology. 8: 10. PMID 18226226 DOI: 10.1186/1471-213X-8-10  1
2008 Wang Y, Werz C, Xu D, Chen Z, Li Y, Hafen E, Bergmann A. Drosophila cbl is essential for control of cell death and cell differentiation during eye development. Plos One. 3: e1447. PMID 18197257 DOI: 10.1371/Journal.Pone.0001447  1
2007 Ahrens CH, Brunner E, Hafen E, Aebersold R, Basler K. A proteome catalog of Drosophila melanogaster: an essential resource for targeted quantitative proteomics. Fly. 1: 182-6. PMID 18820430 DOI: 10.4161/Fly.4532  1
2007 Ryder E, Ashburner M, Bautista-Llacer R, Drummond J, Webster J, Johnson G, Morley T, Chan YS, Blows F, Coulson D, Reuter G, Baisch H, Apelt C, Kauk A, Rudolph T, ... ... Hafen E, et al. The DrosDel deletion collection: a Drosophila genomewide chromosomal deficiency resource. Genetics. 177: 615-29. PMID 17720900 DOI: 10.1534/Genetics.107.076216  1
2007 Brunner E, Ahrens CH, Mohanty S, Baetschmann H, Loevenich S, Potthast F, Deutsch EW, Panse C, de Lichtenberg U, Rinner O, Lee H, Pedrioli PG, Malmstrom J, Koehler K, Schrimpf S, ... ... Hafen E, et al. A high-quality catalog of the Drosophila melanogaster proteome. Nature Biotechnology. 25: 576-83. PMID 17450130 DOI: 10.1038/Nbt1300  1
2007 Aegerter-Wilmsen T, Aegerter CM, Hafen E, Basler K. Model for the regulation of size in the wing imaginal disc of Drosophila. Mechanisms of Development. 124: 318-26. PMID 17293093 DOI: 10.1016/J.Mod.2006.12.005  1
2006 Sesé M, Corominas M, Stocker H, Heino TI, Hafen E, Serras F. The Cdi/TESK1 kinase is required for Sevenless signaling and epithelial organization in the Drosophila eye. Journal of Cell Science. 119: 5047-56. PMID 17118962 DOI: 10.1242/Jcs.03294  1
2006 O'Reilly AM, Ballew AC, Miyazawa B, Stocker H, Hafen E, Simon MA. Csk differentially regulates Src64 during distinct morphological events in Drosophila germ cells. Development (Cambridge, England). 133: 2627-38. PMID 16775001 DOI: 10.1242/Dev.02423  1
2006 Nairz K, Rottig C, Rintelen F, Zdobnov E, Moser M, Hafen E. Overgrowth caused by misexpression of a microRNA with dispensable wild-type function. Developmental Biology. 291: 314-24. PMID 16443211 DOI: 10.1016/J.Ydbio.2005.11.047  1
2005 Gingras AC, Caballero M, Zarske M, Sanchez A, Hazbun TR, Fields S, Sonenberg N, Hafen E, Raught B, Aebersold R. A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity. Molecular & Cellular Proteomics : McP. 4: 1725-40. PMID 16085932 DOI: 10.1074/Mcp.M500231-Mcp200  1
2005 Wittwer F, Jaquenoud M, Brogiolo W, Zarske M, Wüstemann P, Fernandez R, Stocker H, Wymann MP, Hafen E. Susi, a negative regulator of Drosophila PI3-kinase. Developmental Cell. 8: 817-27. PMID 15935772 DOI: 10.1016/J.Devcel.2005.04.002  1
2005 Zipperlen P, Nairz K, Rimann I, Basler K, Hafen E, Hengartner M, Hajnal A. A universal method for automated gene mapping. Genome Biology. 6: R19. PMID 15693948 DOI: 10.1186/Gb-2005-6-2-R19  1
2005 Reiling JH, Doepfner KT, Hafen E, Stocker H. Diet-dependent effects of the Drosophila Mnk1/Mnk2 homolog Lk6 on growth via eIF4E. Current Biology : Cb. 15: 24-30. PMID 15649360 DOI: 10.1016/J.Cub.2004.12.034  1
2005 Desiere F, Deutsch EW, Nesvizhskii AI, Mallick P, King NL, Eng JK, Aderem A, Boyle R, Brunner E, Donohoe S, Fausto N, Hafen E, Hood L, Katze MG, Kennedy KA, et al. Integration with the human genome of peptide sequences obtained by high-throughput mass spectrometry. Genome Biology. 6: R9. PMID 15642101 DOI: 10.1186/Gb-2004-6-1-R9  1
2004 Hafen E. Cancer, type 2 diabetes, and ageing: news from flies and worms. Swiss Medical Weekly. 134: 711-9. PMID 15635489  1
2004 Nairz K, Zipperlen P, Dearolf C, Basler K, Hafen E. A reverse genetic screen in Drosophila using a deletion-inducing mutagen. Genome Biology. 5: R83. PMID 15461801 DOI: 10.1186/Gb-2004-5-10-R83  1
2004 Ryder E, Blows F, Ashburner M, Bautista-Llacer R, Coulson D, Drummond J, Webster J, Gubb D, Gunton N, Johnson G, O'Kane CJ, Huen D, Sharma P, Asztalos Z, Baisch H, ... ... Hafen E, et al. The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster. Genetics. 167: 797-813. PMID 15238529 DOI: 10.1534/Genetics.104.026658  1
2004 Hafen E. Interplay between growth factor and nutrient signaling: lessons from Drosophila TOR. Current Topics in Microbiology and Immunology. 279: 153-67. PMID 14560957  1
2003 Hafen E, Stocker H. How are the sizes of cells, organs, and bodies controlled? Plos Biology. 1: E86. PMID 14691557 DOI: 10.1371/Journal.Pbio.0000086  1
2003 Jünger MA, Rintelen F, Stocker H, Wasserman JD, Végh M, Radimerski T, Greenberg ME, Hafen E. The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. Journal of Biology. 2: 20. PMID 12908874 DOI: 10.1186/1475-4924-2-20  1
2003 Garami A, Zwartkruis FJ, Nobukuni T, Joaquin M, Roccio M, Stocker H, Kozma SC, Hafen E, Bos JL, Thomas G. Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2. Molecular Cell. 11: 1457-66. PMID 12820960 DOI: 10.1016/S1097-2765(03)00220-X  1
2003 Rintelen F, Hafen E, Nairz K. The Drosophila dual-specificity ERK phosphatase DMKP3 cooperates with the ERK tyrosine phosphatase PTP-ER. Development (Cambridge, England). 130: 3479-90. PMID 12810595 DOI: 10.1242/Dev.00568  1
2003 Stocker H, Radimerski T, Schindelholz B, Wittwer F, Belawat P, Daram P, Breuer S, Thomas G, Hafen E. Rheb is an essential regulator of S6K in controlling cell growth in Drosophila. Nature Cell Biology. 5: 559-65. PMID 12766775 DOI: 10.1038/Ncb995  1
2003 Oldham S, Hafen E. Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control. Trends in Cell Biology. 13: 79-85. PMID 12559758  1
2002 Ikeya T, Galic M, Belawat P, Nairz K, Hafen E. Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila. Current Biology : Cb. 12: 1293-300. PMID 12176357 DOI: 10.1016/S0960-9822(02)01043-6  1
2002 Oldham S, Stocker H, Laffargue M, Wittwer F, Wymann M, Hafen E. The Drosophila insulin/IGF receptor controls growth and size by modulating PtdInsP(3) levels. Development (Cambridge, England). 129: 4103-9. PMID 12163412 DOI: 10.5167/Uzh-623  1
2002 Nairz K, Stocker H, Schindelholz B, Hafen E. High-resolution SNP mapping by denaturing HPLC. Proceedings of the National Academy of Sciences of the United States of America. 99: 10575-80. PMID 12149455 DOI: 10.1073/Pnas.162136299  1
2002 Bartke A, Wright JC, Mattison JA, Ingram DK, Miller RA, Roth GS. Dietary restriction and life-span. Science (New York, N.Y.). 296: 2141-2; author reply. PMID 12094784 DOI: 10.1126/science.296.5576.2141  1
2002 Bellotto M, Bopp D, Senti KA, Burke R, Deak P, Maroy P, Dickson B, Basler K, Hafen E. Maternal-effect loci involved in Drosophila oogenesis and embryogenesis: P element-induced mutations on the third chromosome. The International Journal of Developmental Biology. 46: 149-57. PMID 11902676 DOI: 10.1387/Ijdb.11902676  1
2002 Stocker H, Andjelkovic M, Oldham S, Laffargue M, Wymann MP, Hemmings BA, Hafen E. Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB. Science (New York, N.Y.). 295: 2088-91. PMID 11872800 DOI: 10.1126/Science.1068094  1
2002 Radimerski T, Montagne J, Rintelen F, Stocker H, van der Kaay J, Downes CP, Hafen E, Thomas G. dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1. Nature Cell Biology. 4: 251-5. PMID 11862217 DOI: 10.1038/Ncb763  1
2002 Hafen E, Bopp D, Duboule D. The International Journal of Developmental Biology: Preface International Journal of Developmental Biology. 46: 3-4.  1
2001 Morey M, Serras F, Baguñà J, Hafen E, Corominas M. Modulation of the Ras/MAPK signalling pathway by the redox function of selenoproteins in Drosophila melanogaster. Developmental Biology. 238: 145-56. PMID 11784000 DOI: 10.1006/Dbio.2001.0389  1
2001 Rintelen F, Stocker H, Thomas G, Hafen E. PDK1 regulates growth through Akt and S6K in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 98: 15020-5. PMID 11752451 DOI: 10.1073/Pnas.011318098  1
2001 Clancy DJ, Gems D, Harshman LG, Oldham S, Stocker H, Hafen E, Leevers SJ, Partridge L. Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science (New York, N.Y.). 292: 104-6. PMID 11292874 DOI: 10.1126/Science.1057991  1
2001 Halfar K, Rommel C, Stocker H, Hafen E. Ras controls growth, survival and differentiation in the Drosophila eye by different thresholds of MAP kinase activity. Development (Cambridge, England). 128: 1687-96. PMID 11290305 DOI: 10.5167/Uzh-625  1
2001 Brogiolo W, Stocker H, Ikeya T, Rintelen F, Fernandez R, Hafen E. An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control. Current Biology : Cb. 11: 213-21. PMID 11250149 DOI: 10.1016/S0960-9822(01)00068-9  1
2001 Wittwer F, van der Straten A, Keleman K, Dickson BJ, Hafen E. Lilliputian: an AF4/FMR2-related protein that controls cell identity and cell growth. Development (Cambridge, England). 128: 791-800. PMID 11171403 DOI: 10.5167/Uzh-651  1
2000 Oldham S, Böhni R, Stocker H, Brogiolo W, Hafen E. Genetic control of size in Drosophila. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 355: 945-52. PMID 11128988 DOI: 10.1098/Rstb.2000.0630  1
2000 Oldham S, Montagne J, Radimerski T, Thomas G, Hafen E. Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin. Genes & Development. 14: 2689-94. PMID 11069885 DOI: 10.1101/Gad.845700  1
2000 Stocker H, Hafen E. Genetic control of cell size. Current Opinion in Genetics & Development. 10: 529-35. PMID 10980431 DOI: 10.1016/S0959-437X(00)00123-4  1
2000 Jenni M, Basler K, Hafen E, Aguet M. A newly founded Swiss biotech company Chimia. 54: 236-238.  1
1999 Burke R, Nellen D, Bellotto M, Hafen E, Senti KA, Dickson BJ, Basler K. Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells. Cell. 99: 803-15. PMID 10619433 DOI: 10.1016/S0092-8674(00)81677-3  1
1999 Huang H, Potter CJ, Tao W, Li DM, Brogiolo W, Hafen E, Sun H, Xu T. PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development. Development (Cambridge, England). 126: 5365-72. PMID 10556061  1
1999 Montagne J, Stewart MJ, Stocker H, Hafen E, Kozma SC, Thomas G. Drosophila S6 kinase: a regulator of cell size. Science (New York, N.Y.). 285: 2126-9. PMID 10497130 DOI: 10.1126/Science.285.5436.2126  1
1999 Böhni R, Riesgo-Escovar J, Oldham S, Brogiolo W, Stocker H, Andruss BF, Beckingham K, Hafen E. Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4. Cell. 97: 865-75. PMID 10399915 DOI: 10.1016/S0092-8674(00)80799-0  1
1999 Feldmann P, Eicher EN, Leevers SJ, Hafen E, Hughes DA. Control of growth and differentiation by Drosophila RasGAP, a homolog of p120 Ras-GTPase-activating protein. Molecular and Cellular Biology. 19: 1928-37. PMID 10022880 DOI: 10.1128/Mcb.19.3.1928  1
1999 Brunner E, Brunner D, Fu W, Hafen E, Basler K. The dominant mutation Glazed is a gain-of-function allele of wingless that, similar to loss of APC, interferes with normal eye development. Developmental Biology. 206: 178-88. PMID 9986731 DOI: 10.1006/Dbio.1998.9136  1
1998 Eberle KK, Zinsmaier KE, Buchner S, Gruhn M, Jenni M, Arnold C, Leibold C, Reisch D, Walter N, Hafen E, Hofbauer A, Pflugfelder GO, Buchner E. Wide distribution of the cysteine string proteins in Drosophila tissues revealed by targeted mutagenesis. Cell and Tissue Research. 294: 203-17. PMID 9799436 DOI: 10.1007/S004410051170  1
1998 Rommel C, Hafen E. Ras--a versatile cellular switch. Current Opinion in Genetics & Development. 8: 412-8. PMID 9729716 DOI: 10.1016/S0959-437X(98)80111-1  1
1998 Hafen E. Kinases and phosphatases--a marriage is consummated. Science (New York, N.Y.). 280: 1212-3. PMID 9634402 DOI: 10.1126/Science.280.5367.1212  1
1997 Riesgo-Escovar JR, Hafen E, Hou XS, Goldstein ES, Perrimon N, Glise B, Noselli S, Kockel L, Zeitlinger J, Staszewski LM, Mlodzik M, Bohmann D. Connecting up the pathways in Drosophila development. Trends in Cell Biology. 7: 421-2. PMID 17708993 DOI: 10.1016/S0962-8924(97)88135-4  1
1997 Domínguez M, Hafen E. Hedgehog directly controls initiation and propagation of retinal differentiation in the Drosophila eye. Genes & Development. 11: 3254-64. PMID 9389656 DOI: 10.1101/Gad.11.23.3254  1
1997 Riesgo-Escovar JR, Hafen E. Common and distinct roles of DFos and DJun during Drosophila development. Science (New York, N.Y.). 278: 669-72. PMID 9381174 DOI: 10.1126/Science.278.5338.669  1
1997 Rommel C, Radziwill G, Moelling K, Hafen E. Negative regulation of Raf activity by binding of 14-3-3 to the amino terminus of Raf in vivo. Mechanisms of Development. 64: 95-104. PMID 9232600 DOI: 10.1016/S0925-4773(97)00052-X  1
1997 Riesgo-Escovar JR, Hafen E. Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure. Genes & Development. 11: 1717-27. PMID 9224720 DOI: 10.1101/Gad.11.13.1717  1
1997 van der Straten A, Rommel C, Dickson B, Hafen E. The heat shock protein 83 (Hsp83) is required for Raf-mediated signalling in Drosophila. The Embo Journal. 16: 1961-9. PMID 9155022 DOI: 10.1093/Emboj/16.8.1961  1
1996 Leevers SJ, Weinkove D, MacDougall LK, Hafen E, Waterfield MD. The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth. The Embo Journal. 15: 6584-94. PMID 8978685  1
1996 Oellers N, Hafen E. Biochemical characterization of rolledSem, an activated form of Drosophila mitogen-activated protein kinase. The Journal of Biological Chemistry. 271: 24939-44. PMID 8798773 DOI: 10.1074/Jbc.271.40.24939  1
1996 Dickson BJ, van der Straten A, Dominguez M, Hafen E. Mutations Modulating Raf signaling in Drosophila eye development. Genetics. 142: 163-71. PMID 8770593 DOI: 10.5167/Uzh-656  1
1996 Raabe T, Riesgo-Escovar J, Liu X, Bausenwein BS, Deak P, Maröy P, Hafen E. DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Ras1 in Drosophila. Cell. 85: 911-20. PMID 8681385 DOI: 10.1016/S0092-8674(00)81274-X  1
1996 Domínguez M, Brunner M, Hafen E, Basler K. Sending and receiving the hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus. Science (New York, N.Y.). 272: 1621-5. PMID 8658135 DOI: 10.1126/Science.272.5268.1621  1
1996 Guillemin K, Groppe J, Ducker K, Treisman R, Hafen E, Affolter M, Krasnow MA. The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system. Development (Cambridge, England). 122: 1353-62. PMID 8625824 DOI: 10.5167/Uzh-664  1
1996 Domínguez M, Hafen E. Genetic dissection of cell fate specification in the developing eye of Drosophila Seminars in Cell and Developmental Biology. 7: 219-226. DOI: 10.1006/Scdb.1996.0029  1
1995 Dickson BJ, Domínguez M, van der Straten A, Hafen E. Control of Drosophila photoreceptor cell fates by phyllopod, a novel nuclear protein acting downstream of the Raf kinase. Cell. 80: 453-62. PMID 7859287 DOI: 10.1016/0092-8674(95)90496-4  1
1995 Raabe T, Olivier JP, Dickson B, Liu X, Gish GD, Pawson T, Hafen E. Biochemical and genetic analysis of the Drk SH2/SH3 adaptor protein of Drosophila. The Embo Journal. 14: 2509-18. PMID 7781603 DOI: 10.1002/J.1460-2075.1995.Tb07248.X  1
1994 Dickson B, Hafen E. Genetics of signal transduction in invertebrates. Current Opinion in Genetics & Development. 4: 64-70. PMID 8193542 DOI: 10.1016/0959-437X(94)90092-2  1
1994 Biggs WH, Zavitz KH, Dickson B, van der Straten A, Brunner D, Hafen E, Zipursky SL. The Drosophila rolled locus encodes a MAP kinase required in the sevenless signal transduction pathway. The Embo Journal. 13: 1628-35. PMID 8157002 DOI: 10.1002/J.1460-2075.1994.Tb06426.X  1
1994 Reichman-Fried M, Dickson B, Hafen E, Shilo BZ. Elucidation of the role of breathless, a Drosophila FGF receptor homolog, in tracheal cell migration. Genes & Development. 8: 428-39. PMID 8125257 DOI: 10.1101/Gad.8.4.428  1
1994 Brunner D, Oellers N, Szabad J, Biggs WH, Zipursky SL, Hafen E. A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways. Cell. 76: 875-88. PMID 8124723 DOI: 10.1016/0092-8674(94)90362-X  1
1994 Brunner D, Dücker K, Oellers N, Hafen E, Scholz H, Klämbt C. The ETS domain protein pointed-P2 is a target of MAP kinase in the sevenless signal transduction pathway. Nature. 370: 386-9. PMID 8047146 DOI: 10.1038/370386a0  1
1994 Hafen E, Dickson B, Brunner D, Raabe T. Genetic dissection of signal transduction mediated by the sevenless receptor tyrosine kinase in Drosophila. Progress in Neurobiology. 42: 287-92. PMID 8008827 DOI: 10.1016/0301-0082(94)90067-1  1
1993 Hafen E, Dickson B, Raabe T, Brunner D, Oellers N, van der Straten A. Genetic analysis of the sevenless signal transduction pathway of Drosophila. Development (Cambridge, England). 119: 41-6. PMID 27002030  1
1993 Olivier JP, Raabe T, Henkemeyer M, Dickson B, Mbamalu G, Margolis B, Schlessinger J, Hafen E, Pawson T. A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos. Cell. 73: 179-91. PMID 8462098 DOI: 10.1016/0092-8674(93)90170-U  1
1993 Hafen E, Dickson B, Brunner T, Raabe T. Genetic dissection of signal transduction mediated by the sevenless receptor tyrosine kinase in Drosophila. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 340: 273-8. PMID 8103929 DOI: 10.1098/Rstb.1993.0068  1
1993 Hafen E, Dickson B, Raabe T, Brunner D, Oellers N, van der Straten A. Genetic analysis of the sevenless signal transduction pathway of Drosophila. Development (Cambridge, England). Supplement. 41-6. PMID 8049486  1
1992 Dickson B, Sprenger F, Morrison D, Hafen E. Raf functions downstream of Ras1 in the Sevenless signal transduction pathway. Nature. 360: 600-3. PMID 1461284 DOI: 10.1038/360600A0  1
1992 Dambly-Chaudière C, Jamet E, Burri M, Bopp D, Basler K, Hafen E, Dumont N, Spielmann P, Ghysen A, Noll M. The paired box gene pox neuro: a determinant of poly-innervated sense organs in Drosophila. Cell. 69: 159-72. PMID 1348214 DOI: 10.1016/0092-8674(92)90127-X  1
1992 Dickson B, Sprenger F, Hafen E. Prepattern in the developing Drosophila eye revealed by an activated torso--sevenless chimeric receptor. Genes & Development. 6: 2327-39. PMID 1334023 DOI: 10.1101/Gad.6.12A.2327  1
1991 Basler K, Christen B, Hafen E. Ligand-independent activation of the sevenless receptor tyrosine kinase changes the fate of cells in the developing Drosophila eye. Cell. 64: 1069-81. PMID 2004416 DOI: 10.1016/0092-8674(91)90262-W  1
1991 Basler K, Hafen E. Specification of cell fate in the developing eye of Drosophila. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 13: 621-31. PMID 1789779 DOI: 10.1002/Bies.950131202  1
1991 Hafen E, Basler K. Specification of cell fate in the developing eye of Drosophila. Development (Cambridge, England). Supplement. 1: 123-30. PMID 1742497  1
1990 Hafen E, Basler K. Role of receptor tyrosine kinases during Drosophila development. Ciba Foundation Symposium. 150: 191-204; discussion . PMID 2164907  1
1990 Hafen E, Basler K. Mechanisms of positional signalling in the developing eye of Drosophila studied by ectopic expression of sevenless and rough. Journal of Cell Science. Supplement. 13: 157-68. PMID 1982113 DOI: 10.1242/Jcs.1990.Supplement_13.15  1
1990 Basler K, Yen D, Tomlinson A, Hafen E. Reprogramming cell fate in the developing Drosophila retina: transformation of R7 cells by ectopic expression of rough. Genes & Development. 4: 728-39. PMID 1974229 DOI: 10.1101/Gad.4.5.728  1
1990 Basler K, Hafen E. Receptor tyrosine kinases mediate cell-cell interactions during Drosophila development. Progress in Growth Factor Research. 2: 15-27. PMID 1966557 DOI: 10.1016/0955-2235(90)90007-7  1
1989 Basler K, Siegrist P, Hafen E. The spatial and temporal expression pattern of sevenless is exclusively controlled by gene-internal elements. The Embo Journal. 8: 2381-6. PMID 2792089 DOI: 10.1002/J.1460-2075.1989.Tb08367.X  1
1989 Basler K, Hafen E. Dynamics of Drosophila eye development and temporal requirements of sevenless expression. Development (Cambridge, England). 107: 723-31. PMID 2632232  1
1989 Basler K, Hafen E. Ubiquitous expression of sevenless: position-dependent specification of cell fate. Science (New York, N.Y.). 243: 931-4. PMID 2493159 DOI: 10.1126/Science.2493159  1
1988 Basler K, Hafen E. Sevenless and Drosophila eye development: a tyrosine kinase controls cell fate. Trends in Genetics : Tig. 4: 74-9. PMID 3076295 DOI: 10.1016/0168-9525(88)90044-3  1
1988 Basler K, Hafen E. Control of photoreceptor cell fate by the sevenless protein requires a functional tyrosine kinase domain. Cell. 54: 299-311. PMID 2840202  1
1987 Tomlinson A, Bowtell DD, Hafen E, Rubin GM. Localization of the sevenless protein, a putative receptor for positional information, in the eye imaginal disc of Drosophila. Cell. 51: 143-50. PMID 3115593 DOI: 10.1016/0092-8674(87)90019-5  1
1987 Hafen E, Basler K, Edstroem JE, Rubin GM. Sevenless, a cell-specific homeotic gene of Drosophila, encodes a putative transmembrane receptor with a tyrosine kinase domain. Science (New York, N.Y.). 236: 55-63. PMID 2882603 DOI: 10.1126/Science.2882603  1
1985 Montell C, Jones K, Hafen E, Rubin G. Rescue of the Drosophila phototransduction mutation trp by germline transformation. Science (New York, N.Y.). 230: 1040-3. PMID 3933112 DOI: 10.1126/Science.3933112  1
1984 Hafen E, Kuroiwa A, Gehring WJ. Spatial distribution of transcripts from the segmentation gene fushi tarazu during Drosophila embryonic development. Cell. 37: 833-41. PMID 6430568 DOI: 10.1016/0092-8674(84)90418-5  1
1984 Kuroiwa A, Hafen E, Gehring WJ. Cloning and transcriptional analysis of the segmentation gene fushi tarazu of Drosophila. Cell. 37: 825-31. PMID 6430567 DOI: 10.1016/0092-8674(84)90417-3  1
1984 Hafen E, Levine M, Gehring WJ. Regulation of Antennapedia transcript distribution by the bithorax complex in Drosophila. Nature. 307: 287-9. PMID 6420705 DOI: 10.1038/307287a0  1
1984 McGinnis W, Levine MS, Hafen E, Kuroiwa A, Gehring WJ. A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes. Nature. 308: 428-33. PMID 6323992 DOI: 10.1038/308428A0  1
1983 Levine M, Hafen E, Garber RL, Gehring WJ. Spatial distribution of Antennapedia transcripts during Drosophila development. The Embo Journal. 2: 2037-46. PMID 6416828  1
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